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EUROIMMUN Medizinische Labordiagnostika AG Product Catalogue Diagnostics for the Determination of Autoantibodies, for Infectious Serology and Allergology Indirect Immunofluorescence — ELISA — RIA — Westernblot EUROASSAY — EUROLINE — EUROPLUS 2008

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Page 1: Product Catalogue - EUROIMMUNtypo3.euroimmun.de/fileadmin/template/images/pdf/Cat2008...development is shaped by continuous growth. Although the diagnostic market in Germany stagnated

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

Product Catalogue

Diagnostics for the Determination of Autoantibodies,

for Infectious Serology and Allergology

Indirect Immunofluorescence — ELISA — RIA — Westernblot

EUROASSAY — EUROLINE — EUROPLUS

2008

g

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

Table of Contents

EUROIMMUN – Company Profile .................................................................................................................................................. 4

Techniques for the Serological Investigation of Antibodies ........................................................................................................ 5Indirect Immunofluorescence: An Easy and Modern Method ................................................................................................................................ 6BIOCHIP Mosaics™ ..................................................................................................................................................................................................... 9The Indirect Immunofluorescence Test, Performed Using the TITERPLANE™ Technique ............................................................................... 10Recommended Serum Dilutions for Indirect Immunofluorescence .................................................................................................................... 12Diagnostically Relevant Systemic Autoantibodies ................................................................................................................................................ 16Organ-/Tissue-Specific Autoantibodies ................................................................................................................................................................... 17Antibodies for Infectious Serology .......................................................................................................................................................................... 18Antibodies for Allergology ....................................................................................................................................................................................... 19EUROIMMUN Microplate ELISA .............................................................................................................................................................................. 18ELISA Automation using the EUROIMMUN Analyzer I ......................................................................................................................................... 22Incubating the Microplate ELISA ............................................................................................................................................................................. 23EUROASSAY: A New Technique for the Determination of Antibody Profiles .................................................................................................... 24Incubating the EUROASSAY (TITERPLANE™Technique) ..................................................................................................................................... 25The EUROLINE: A New Technique for Extensive Antibody Profiles .................................................................................................................... 26Incubating the EUROLINE ......................................................................................................................................................................................... 27Westernblots/EUROLINE-WB: Reliable Differentiation of Antibodies Present .................................................................................................... 28Incubating the Westernblot/EUROLINE-WB ............................................................................................................................................................ 29EUROIMMUN Radioimmunoassays (RIA/IRMA) .................................................................................................................................................... 30

EUROIMMUN Products for the Determination of Autoantibodies ............................................................................................. 31Autoantibodies against Cell Nuclei (ANA) .............................................................................................................................................................. 32Autoantibodies against Double-Stranded DNA (dsDNA) ...................................................................................................................................... 35Autoantibodies against Cyclic Citrullinated Peptide (CCP) ................................................................................................................................... 36Autoantibodies against Mitochondria (AMA) ......................................................................................................................................................... 37Autoantibodies against Liver Antigens ................................................................................................................................................................... 38Autoantibodies against Thyroid Gland Antigens / Antigen Detections ............................................................................................................... 40Autoantibodies against Neuronal Antigens ............................................................................................................................................................ 41Autoantibodies against Islet Cell Antigens ............................................................................................................................................................. 42Autoantibodies against Parietal Cells (PCA) ........................................................................................................................................................... 43Autoantibodies against Granulocyte Cytoplasm (cANCA/pANCA) ...................................................................................................................... 44Antibodies against Endomysium and Gliadin ........................................................................................................................................................ 46

EUROIMMUN Products for Infectious Serology ......................................................................................................................... 47Antibodies against Borrelia/TBE Virus .................................................................................................................................................................... 48Antibodies against Epstein-Barr Virus (EBV) .......................................................................................................................................................... 50Antibodies against Helicobacter Pylori ................................................................................................................................................................... 52Antibodies against Herpes Simplex Virus (HSV) ................................................................................................................................................... 53BIOCHIP Mosaics™ for Infectious Serology ........................................................................................................................................................... 54IgG Absorption in Preparation for the Determination of Specific IgM Class Antibodies .................................................................................. 56

EUROIMMUN Products for Allergology ...................................................................................................................................... 57

Order Information and Product Data .......................................................................................................................................... 60Fluorescence-Labelled Antibodies: Fluorescein (FITC) for EUROIMMUN IIFT ................................................................................................... 61Controls for EUROIMMUN IIFT: Organ-Specific Autoantibodies ......................................................................................................................... 62Controls for EUROIMMUN IIFT: Systemic Autoantibodies ................................................................................................................................... 64Controls for EUROIMMUN IIFT: Infectious Serology ............................................................................................................................................. 66Controls for EUROIMMUN IIFT: Determination of Further Antibodies ................................................................................................................ 72Controls for EUROIMMUN Westernblots/EUROLINE-WB ..................................................................................................................................... 73EUROASSAY for the Determination of Autoantibodies (Test Systems) ............................................................................................................. 75EUROASSAY for Allergology (Test Systems) ........................................................................................................................................................ 76EUROLINE for the Determination of Autoantibodies (Test Systems) .................................................................................................................. 76EUROLINE for Infectious Serology (Test Systems) ............................................................................................................................................... 77EUROLINE for Allergology (Test Systems) ............................................................................................................................................................. 77Westernblot/EUROLINE-WB for the Determination of Autoantibodies (Test Systems) ..................................................................................... 78Westernblot/EUROLINE-WB for Infectious Serology (Test Systems) .................................................................................................................. 79Microplate ELISA for the Determination of Autoantibodies (Test Systems) ...................................................................................................... 81Radioimmunoassay (RIA) for the Determination of Autoantibodies / Autoantigens / Hormone Determination (Test Systems) ................. 84Microplate ELISA for Infectious Serology (Test Systems) .................................................................................................................................... 85Microplate ELISA for the Determination of Antibodies against Other Antigens (Test Systems) ..................................................................... 89Allercoat™ 6 System ................................................................................................................................................................................................. 90Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies .............................................................................................. 120Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies ........................................................................................................ 129Diagnostics for Indirect Immunofluorescence: Infectious Serology .................................................................................................................. 137Diagnostics for Indirect Immunofluorescence: Other Antigens ......................................................................................................................... 154Further Reagents for EUROIMMUN IIFT ............................................................................................................................................................... 155Other Items for EUROIMMUN IIFT ........................................................................................................................................................................ 155General Delivery Conditions .................................................................................................................................................................................. 156

Index ......................................................................................................................................................................................... 157

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

EUROIMMUN – COMPANY PROFILE

EUROIMMUN was founded in September 1987 and today has its headquarters in Lübeck, Germany. Branchesare situated in Groß Grönau near Lübeck, in Rennersdorf (Upper Lusatia, Saxony) and in Pegnitz (UpperFranconia, Bavaria). Further EUROIMMUN subsidiaries can be found in Canada (Mississauga), China(Beijing, Hangzhou), Great Britain (Pontypool in Wales), Italy (Padua), Lebanon (Beirut), Poland(Wroclaw), Switzerland (Lucerne), Singapore, South Africa (Capetown), Turkey (Istanbul), the USA(New Jersey) and the United Arab Emirates (Dubai). At present EUROIMMUN has 500 employees inGermany, 630 worldwide. The company is ISO-certified (EN ISO 9001:2000, EN ISO 13485:2003, ISO 13485/CMDCAS).

EUROIMMUN produces reagents for medical laboratory diagnostics. In the foreground are test systemsfor the determination of various antibodies in patient serum in the diagnosis of autoimmune diseases,infectious diseases and allergies.

The test methods employed are predominantly indirect immunofluorescence, microplate ELISA, variousblot techniques (Westernblot, EUROASSAY, EUROLINE, EUROLINE-WB) and all molecular biologytechniques. The company is based on worldwide-patented state-of-the-art production methods andmicroanalysis techniques and is one of the world’s leading manufacturers of medical laboratory diagnostics.

The BIOCHIPs are one of EUROIMMUN’s many inventions: paper-thin sheets of glass are coated with cells ortissue sections and then cut automatically into millimetre-sized fragments which are subsequently glued ontoslides using a fully automated device. This BIOCHIP technology allows extreme miniaturization andstandardization of immunbiochemical analyses. With BIOCHIP Mosaics™made from 30 or more differentorgan sections, cell substrates or defined antigens (EUROPLUS™) only minimum incubation efforts arenecessary to obtain a detailed antibody profile.

In EUROIMMUN enzyme immunoassays (ELISA) defined antigens, purified using state-of-the-artbiotechnological processes, are employed as the antigen substrate. Some of these antigens are synthesized inthe company’s molecular biology laboratories. EUROIMMUN ELISA are characterized by their excellent stability,simple handling and short incubation times, and they are ideal for automated use. All reagents are deliveredready-to-use and are exchangeable between different lots. EUROIMMUN offers the largest and mostdifferentiated arsenal of enzyme immunoassays worldwide for the diagnosis of autoimmune and infectiousdiseases.

The innovative procedures EUROASSAY and EUROLINE developed by EUROIMMUN follow the same testprinciple as the ELISA methods, with the use of the BIOCHIP technology. At EUROIMMUN purified antigens areprinted in parallel lines at defined positions on membrane strips. Following incubation, users can evaluateresults visually without additional equipment. These reagents allow in particular the differentiation of antibodiesthat are not clearly defined microscopically by indirect immunofluorescence. EUROASSAY and EUROLINE arealso employed in laboratories where no sophisticated laboratory instruments are available.

Company site Groß Grönau Company headquarters Lübeck Company branch Rennersdorf

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EUROIMMUN produces an extensive range of Westernblot strip test systems and corresponding reagents forconfirmation of positive fluorescence and ELISA results as well as clarification of difficult-to-interpret results inautoimmune diagnostics, infectious serology and allergology. Refined electrophoretical processes have beendeveloped to allow the precise separation of diagnostically relevant proteins from one another. Lot-specificevaluation templates are produced for the evaluation of band patterns. The program ”EUROLineScan“ enablescomputer-based evaluation and simplifies the archiving of results with large sample series.

One of the company’s main strengths is its technical expertise. This encompasses not just the manufacture andsale of medical laboratory diagnostics, but also the diagnostic application of the products in a referencelaboratory which provides highly differential diagnostics. This reference laboratory has set standards inGermany, and worldwide is unequalled in the whole field of autoimmune diagnostics. The diagnostic spectrumof the laboratory also covers the areas of infectious serology and serological allergy diagnostics. The referencelaboratory receives hundreds of serum samples daily from all over Germany as well as from many othercountries. It helps EUROIMMUN customers to secure their results: a large proportion of serum samples sent toEUROIMMUN for evaluation are analysed free of charge in order to maintain high standards in the laboratoriesof EUROIMMUN customers.

Customers can obtain further technical information from experienced scientists in the company, with whomthey can also discuss serological problem cases. The “Institute for Quality Assurance”, an institution newlyfounded by EUROIMMUN, organises unbiased quality assessments and provides advice in the area of qualitymanagement. Moreover EUROIMMUN has established the “Institute for experimental Immunology”, which isengaged in basic research.

In October 2007, the EUROIMMUN workforce included 92 university and college graduates, amongthese biologists, biochemists, chemists, engineers and medical doctors (26 of them holding a doctor’s degree).Medical technicians are particularly strongly represented with 95 people, corresponding to EUROIMMUN’sactivities, as well as biology/chemistry laboratory technicians (44). At present the company is training 37 youngpeople as biology laboratory assistants, industrial clerks, IT specialists, electronic system technicians, electronictechnicians for devices and systems and industrial mechanics.

At EUROIMMUN great value is placed on advising customers and prospective customers in a factual,technical and commercially restrained manner and fully supporting them in the use of our diagnosticallydemanding products. EUROIMMUN products are backed by an energetic and competent sales force, qualifiedinformation material, didactic test instructions and scientifically based, but nevertheless understandableadvertisements in technical journals. Advertising material is produced in-house using the latest desktoppublishing methods, right up until the fully digitalised ready-for-exposure documents. The most importantpublications and posters are translated into many languages. EUROIMMUN has set up an informative homepageon the internet (www.euroimmun.com) which is visited extensively internationally.

Over 3,000 laboratories worldwide use EUROIMMUN diagnostics: 400 of these are in Germany and therest are found in countries including, among others, Algeria, Australia, Austria, Bangladesh, Belgium, Bosnia-Herzegovina, Brazil, Bulgaria, Canada, China, Croatia, Cyprus, the Czech Republic, Denmark, Egypt, Estonia,Finland, France, Great Britain, Greece, Hongkong, Hungary, India, Indonesia, Iran, Iraq, Ireland, Israel, Italy,Japan, Jordan, Kuwait, Latvia, Lebanon, Lithuania, Luxembourg, Malaysia, Malta, Mexico, Morocco, theNetherlands, New Zealand, Norway, Peru, Poland, Portugal, Qatar, Russia, Saudi-Arabia, Serbia and Montenegro,Singapore, Slovakia, Slovenia, Spain, South Africa, South Korea, Sri Lanka, Sweden, Switzerland, Syria, Taiwan,Thailand, Tunisia, Turkey, the Ukraina, the United Arab Emirates, USA, Venezuela, Yemen. The company’sdevelopment is shaped by continuous growth. Although the diagnostic market in Germany stagnated and hasbecome particularly strongly competitive, EUROIMMUN has been able to continue its strong expansion. Thecompany is achieving an ever increasing independence from the German market, since more and more productsare sold abroad. With their quality and standardization, EUROIMMUN products are capturing the leadingposition in the world.

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TECHNIQUES FOR THE SEROLOGICAL INVESTIGATION OF ANTIBODIES

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FITC

FITC

cell withantigen

specific humanantibody

FITC-labelled anti-human antibody

Principle of the Test

• For the determination of autoantibodies or antibodies against infectious agents,cells, tissue sections or purified, biochemically characterized substances are usedas antigen substrates.

• If the sample is positive, specific antibodies in the diluted serum sample attach tothe antigens coupled to a solid phase.

• In a second step, the attached antibodies are stained with fluorescein-labelledanti-human antibodies and visualized with the fluorescence microscope.

• Positive samples can be titrated in steps. The most suitable titration interval isprovided by the dilution factor 3.162 (square root of 10). In this way, every secondstep represents in its denominator an integral power of 10 (1 : 10, 1 : 32, 1 : 100,1 : 320, 1 : 1000, 1 : 3200, 1 : 10000 etc.).

Indirect Immunofluorescence: A Standardized Technique for theDetermination of Autoantibodies and Antibodies against InfectiousAgents

• High specificity: positive and negative samples produce a large difference insignal strength. Each bound antibody shows a typical fluorescence patterndepending on the location of the individual antigens.

• The entire antigen spectrum of the original subtrate is available, thus allowingthe detection of a large number of antibodies and achieving a higher detectionrate.

• Immunofluorescence enables simultaneous detection of antibodies againstseveral biochemically different antigens on one single biological substrate.

• The indirect immunofluorescence test is the analytical method of choice when itwould be too difficult or too complicated to prepare the test antigens individuallyfor enzyme immunoassays.

Pattern homog. Anti-dsDNA? Anti-Histones?

EUROIMMUN’s Innovations for the Standardization and Modern-ization of Indirect Immunofluorescence

• Activation technique: physically or chemically activated cover glasses are coatedwith cultured cells or tissue sections. Frozen tissue sections are fixed to the glasssurface by covalent bonding, increasing adhesion more than 100 times and thuspreventing the substrates from being detached.

• BIOCHIP Technology: cover glasses coated with biological substrates are cut intomillimetre-sized fragments (BIOCHIPs) on a machine. This makes it possible toobtain ten or more first-class preparations of homogeneous quality per tissuesection, in the case of cultured cell substrates even several thousands.

• BIOCHIP Mosaics™: using several BIOCHIPs coated with different substrates sideby side on one and the same reaction field, antibodies against various organs orinfectious agents can be investigated simultaneously. Detailed antibody profilescan thus be established with comparatively little effort, allowing the reciprocaldetermination of the results on different substrates.

• TITERPLANE™ Technique: samples or reagents are applied to the reaction fieldsof a reagent tray. The BIOCHIP Slides are then placed into the recesses of thereagent tray, where all BIOCHIPs come into contact with the fluids, and theindividual reactions commence simultaneously. As the fluids are confined in aclosed space, there is no need for the use of a conventional „humidity chamber“.

Pattern fine-granular.Anti-SS-A? Anti-SS-B?

Pattern nucleolar. Anti-PM-Scl?

Pattern cytoplasmic.AMA M2?

Differentiation of antibodies using HEp-2 cells.

Indirect Immunofluorescence: An Easy and Modern Method

BIOCHIP Technology and Mosaics.

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Indirect Immunofluorescence: An Easy and Modern Method

Chemically Activated Slides for Histochemistry

• For diagnostics of organ-specific or tissue-specific autoantibodies frozen tissuesections of various organs are used. However, formerly, the morphology oftissues suffered during incubation in aqueous medium, tissue parts occasionallybecame detached from slides, and the interpretation of results was difficult.

• Using the activation technique for the first time in histology, we have appliedsolid phase techniques. Firstly, the surface of cover glasses is coated withspontaneously reactive aldehyde groups. In a second step, the tissue sectionsare applied to the chemically activated cover glasses (Stöcker, W: EuropeanPatent No. 0 117 262; U.S. Patent No. 4,647,543). Free amino groups of the tissuesections, especially of the hydroxylysine contained in the collagen, bind to thecarrier material by covalent bonding.

• This results in an increased adhesion of frozen tissue sections more than ahundredfold and prevents them from being detached during incubation.Furthermore, in some cases the activation technique results in a significantlybetter conservation of tissue structures, especially in organs which previouslyexhibited a generally low level of adhesion. Therefore, the tests can be evaluatedwith considerably greater confidence.

Fixation of frozen tissue sections to glass surfacesby covalent bonding.

Determination of Low-Avidity Antibodies

• An alternative principle for the serological diagnosis of fresh infections has beenestablished by investigating the antibody avidity.

• The first reaction of the immune system following an infection is the formation oflow-avidity antibodies. As the infection proceeds, increasingly antigen-adaptedIgG is formed, and avidity grows. As long as high-avidity IgG is not yet detectedin the serum, it can be assumed that the infection is still in an early stage.

• To identify low-avidity antibodies in a patient’s serum, two immunofluorescencetests are performed in parallel: one test is carried out in the conventional way,the other one includes urea treatment between incubations with patient’s serumand peroxidase-labelled anti-human IgG, resulting in the detachment of low-avidity antibodies from the antigens.

• Low-avidity antibodies are present if the fluorescence intensity is significantlyreduced (two intensity levels ore more) by urea treatment.

• The following test kits for avidity determination are available: Toxoplasma gondii,Rubella virus, West-Nile virus, EBV-EA, EBV-CA.

high-avide Ab against EBV-CA

low-avide Ab against EBV-CA

without urea with urea

Si

(CH2)3

NH

(CH2)2

N

(CH2)3

HC

HC

N

frozen tissue section

O

OSi

(CH2)3

NH

(CH2)2

N

(CH2)3

HC

HC O

NH2

frozen tissue section

O

OSi

(CH2)3

NH

(CH2)2

NH2

(CH2)3

HC O

HC O

glutardialdehyde

O

O

Si

(CH2)3

NH

(CH2)2

NH2

OCH3

OCH3

H3CO

glass

Aminoethyl-

aminoproyl-

trimethoxysilane

OH

- H2O- 3 CH3OH - H2O

EUROPLUS™ System: Combination of conventional immuno-fluorescence substrates and monospecific tests

• In EUROPLUS™ immunofluorescence tests antibody detection is performedusing both tissue sections/cell substrates and monospecifically reacting antigendots.

• Antibodies detected in IFT screening tests can therefore be differentiated orconfirmed with one and the same reaction field. In some cases, the antigen dotshelp to extend the antigen spectrum, offering a wider range for screening.

• BIOCHIPs coated with purified or recombinant antigens in droplet form are usedas monospecific substrates.

• A positive result shows green circular areas of antigen dots in front of a darkbackground under the microscope.

• In some EUROPLUS™ test systems several different antigens are coated on oneBIOCHIP in separate antigen rows. In this manner, several monospecific analysescan be performed using a single BIOCHIP.

• Many different BIOCHIP combinations for various diagnostic investigations areavailable.

EUROPLUS™: BIOCHIP combination of tissuesections/cell substrates (left) and antigen dots(right).

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Indirect Immunofluorescence: An Easy and Modern Method

New: Hydrophobic Slides

• EUROIMMUN has developed a specific slide surface with hydrophobic properties.

• This prevents the droplets from spreading on the slide surface. The slides arenow suitable for manual incubation using TITERPLANE Technique and non-manual incubation on automated systems.

• The reaction fields must not be marked with a Cytomation Pen anymore.

• Price and order number are the same as for conventional EUROIMMUN slides(please add "hydrophobic" when ordering)

• Hydrophobic slides are available on request for many products.

AP16/22 by DAS: Automated Solution for all EUROIMMUNImmunofluorescence Tests

• Various validated parameters. Slide definitions and test files are provided on CD.

• CE conformity for device/test system combination.

• Capacity: 16 slides, 80 samples, 200 dilutions.

• Programmable for 8 methods per run.

• 10 dilution series freely programmable.

• Automated sample dilution, sample and reagent dispension, incubation andwashing of slides.

• Laboratory software interface.

• The incubation protocol for result documentation is automatically created fromthe worklist.

• Barcode reader available on request.

Fluorescence Microscope EUROStar II

• The EUROStar II is specifically tailored to the requirements of indirect immuno-fluorescence. Unnecessary and partly expensive components have been de-liberately left out of the design and the conventional complex illumination fittingshave been replaced by the stunningly simple EUROStar Bluelight system.

• With the EUROStar Bluelight, engineers at EUROIMMUN AG have introducedblue light-emitting diodes to fluorescence microscopy. Almost all the emittedlight is suitable for the excitation of fluorescein. Only requiring a tenth of theelectrical power (low heat formation) the EUROStar Bluelight dispenses the sameamount of utilisable exciting light as a 50 watt HBO mercury lamp.

• The EUROStar Bluelight does not emit any ultraviolet radiation and is explosionproof. The large ballast and (interference-prone) inverter have been left out.

• The EUROStar Bluelight is immediately ready for operation after being switchedoff and offers instant full output after being switched on again. The LED shinesfor 15,000 hours – which is 150 times longer than a mercury vapour lamp. Thus,the microscope requires almost no maintenance.

• Light flux electronically maintained at a constant level over the whole life span.

• A white LED light source for transmitted-light microscopy is available on request.

Above: conventional slideBelow: hydrophobic slide.

AP22 by DAS.

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BIOCHIP Mosaics™

For indirect immunofluorescence products, slides can be coated with individual substrates orBIOCHIP Mosaics™ consisting of up to 45 different substrates, depending on customers’individual requirements and specifications. Thyroid gland, parathyroid gland, pancreas, adrenal gland,ovary, placenta*, testis, spermatozoa, pituitary gland, hypothalamus*, cerebrum, cerebellum, pons*, lobustemporalis, substantia nigra*, peripheral nerve, spinal cord, eye, granulocytes (fixed with ethanol orformaldehyde), lymphocytes, monocytes*, thrombocytes, kidney, lung*, liver, mouth mucosa*, stomach (corpus,antrum*), jejunum, colon, umbilical cord, mamma*, lacrimal gland*, parotid gland, prostate*, vesiculaseminalis*, skeletal muscle, heart muscle, thymus*, lipocytes*, cartilage*, epidermis, oesophagus, tongue, lip*,melanocytes*, HEp-2 cells, HEp-20-10 cells, HUVEC, rat kidney, mouse kidney, rat stomach, mouse stomach,rat liver, mouse liver, rat oesophagus, Crithidia luciliae etc. Adenovirus, Afipia felis*, Bartonella henselae,Bartonella quintana, Bordetella parapertussis, Bordetella pertussis, Borrelia afzelii, Borrelia burgdorferi(strains CH, USA), Borrelia garinii, Campylobacter coli*, Campylobacter jejuni*, Candida albicans, Candidaglabrata*, Candida krusei*, Candida parapsilosis*, Candida tropicalis*, Chlamydia pneumoniae, Chlamydiatrachomatis, Chlamydia psittaci*, CMV, Coxsackievirus (A7, A9, A16, A24, B1 to B6), EBV-CA, EBNA, EBV-EA,Echinococcus granulosus, ECHO virus, Haemophilus influenzae*, Helicobacter pylori, HIV-1*, HIV-2*, HHV-6,HSV-1, HSV-2, Influenza A (strains Shangdong, Singapore and Beijing), Influenza B (strain Panama), Klebsiellapneumoniae*, Legionella bozemanii*, Legionella dumoffii*, Legionella gormanii*, Legionella jordanis*,Legionella longbeachae, Legionella micdadei*, Legionella pneumophila (serotypes 1 to 14), Leishmaniadonovani, Listeria monocytogenes (1/2a and 4b)*, measles virus, mumps virus, Mycoplasma hominis,Mycoplasma pneumoniae, Parainfluenza 1 to 4, rubella virus, RSV, Saccharomyces cerevisiae, SARS-CoV, TBEvirus, Toxoplasma gondii, Treponema pallidum, Treponema phagedenis, Ureaplasma urealyticum, VZV, West-Nile-Virus, Yersinia enterocolitica (O:3, O:4, O:6 and O:9)*. EUROPLUS™: thyroid gland plus thyroglobulin,granulocytes (ANCA) plus MPO / PR3, HEp-2 cells (ANA) plus SS-A / SS-B / RNP/Sm / Sm / Scl-70 / Jo-1 / rib. P-prot., rat kidney plus AMA M2 / Sp100, primate stomach (parietal cells) plus intrinsic factor, small intestine(endomysium) plus gliadin, Borrelia plus VlsE/OspC. *) Currently not available as IVD in the EU.

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(Reaction fields 5 x 5 mm)

The TITERPLANE™ Technique was developed by EUROIMMUN in order to standardize immunologicalanalyses: Samples or labelled antibodies are applied to the reaction fields of a reagent tray. The BIOCHIPSlides are then placed into the recesses of the reagent tray, where all BIOCHIPs of the slide come into contactwith the fluids, and the individual reactions commence simultaneously. Position and height of the droplets areexactly defined by the geometry of the system. As the fluids are confined in a closed space, there is no need forthe use of a conventional ”humidity chamber”. It is possible to incubate any number of samples next to eachother and simultaneously under identical conditions.

Prepare: Check the reagent tray: Are the reaction fields hydrophiIic and the surrounding coating hydrophobic?If not, rub with a wet paper towel, using normal household detergent or Extran MA 01 (Merck) if necessary, andrinse thoroughly with water. For occasional disinfection, immerse for 1 h in 3% Sekusept Extra (Henkel) in water.Open the individual packets containing the BIOCHIP Slides only after they have reached room temperature. Donot touch the BIOCHIPs. Mark BIOCHIP Slides as required with a felt pen.

Dilute: Dilute serum samples according to the user’s test protocol. Include positive and negative controls withevery test procedure. Mix control sera before use.

Pipette: Apply 25 µl of diluted serum to each reaction field of the reagent tray, avoiding air bubbles. Transfer allsamples to be tested before starting the incubation (up to 200 droplets). Use a polystyrene pipetting template.

Incubate: Start reactions by fitting the BIOCHIP Slides into the corresponding recesses of the reagent tray.Ensure that each sample makes contact with its BIOCHIP and that the individual samples do not come intocontact with each other. Incubate for 30 min at room temperature.

Wash: Rinse the BIOCHIP Slides with a flush of PBS-Tween using a beaker, and immerse them immediatelyafterwards in a cuvette containing PBS-Tween for at least 5 min.

Pipette: Apply 20 µl of fluorescein-labelled anti–human immunoglobulin (conjugate) onto each reaction field ofa clean reagent tray. Add all drops (reagent for a maximum of 50 slides) before continuing incubation. Use astepper pipette. The labelled anti-human serum should be mixed with a pipette before use. To save time,conjugate can be pipetted onto separate reagent trays during incubation with the diluted serum.

Incubate: Remove one BIOCHIP Slide from the PBS-Tween and within five seconds blot only the back and thelong edges with a paper towel and immediately put the BIOCHIP Slide into the recesses of the reagent tray. Donot dry the areas between the reaction fields. Check for correct contact between the BIOCHIPs and liquids. Thencontinue with the next BIOCHIP Slide. From now on, protect the slides from direct sunlight. Incubate for 30 minat room temperature.

Wash: Rinse the BIOCHIP Slides with a flush of PBS-Tween using a beaker and put them in a cuvette containingPBS-Tween for at least 5 min. 10 drops of Evans Blue (150 µl) for each 150 ml phosphate buffer can be added forcounterstaining.

Embed: Place glycerol/PBS onto a cover glass – drops of 10 µl per reaction field. Use a polystyrene embeddingtemplate. Remove one BIOCHIP Slide from the PBS-Tween and dry the back and all four edges as well as the surfacearound, but not between, the reaction fields with a paper towel. Put the BIOCHIP Slide, with the BIOCHIPs facingdownwards, onto the prepared cover glass. Check immediately that the cover glass is properly fitted into therecesses of the slide. Correct the position if necessary. Now proceed in the same way with the next BIOCHIP Slide.

Evaluate: Read the fluorescence under the microscope.

The Indirect Immunofluorescence Test, Performed Using the

TITERPLANE™ Technique

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20xNEOFLUAR

The Indirect Immunofluorescence Test, Performed Using the

TITERPLANE™ Technique

Pipette:10 µl per field (3 x 3 mm)25 µl per field (5 x 5 mm)70 µl per field (7 x 9 mm)

Pipette:10 µl per field (3 x 3 mm)20 µl per field (5 x 5 mm)60 µl per field (7 x 9 mm)

Embed:10 µl per field (3 x 3 mm)10 µl per field (5 x 5 mm)20 µl per field (7 x 9 mm)

Incubate: 30 min

Incubate: 30 min

Evaluate: fluorescence microscopy

Wash: 1 s flush5 min cuvette

Wash: 1 s flush5 min cuvette

slide

reagent trayBIOCHIPs

diluted samples

PBS-Tween

labelled antibody

PBS-Tween

glycerol/PBS

cover glass

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Recommended Serum Dilutions for Indirect Immunofluorescence

– Autoimmunity –

Antibodies against Substrate IgA IgG IgM IgAGM

*) In addition to the preferential analysis or as a plausibility check.**) Hepatitis Mosaic: liver, monkey / heart, monkey / HEp-2 cells / liver, rat / kidney, rat / stomach, rat.

acetylcholine receptor *skeletal muscle, monkey / heart, monkey 100actin Hepatitis Mosaic** 10 10 100ADH-producing cells nucl. supraopticus & paraventricularis, monkey 10 10adrenal cortex adrenal gland, monkey 10alveolar basement membrane lung, monkey / kidney, monkey 10

asialoglycoprotein receptors *Hepatitis Mosaic** 100basic myelin protein (BMP) cerebellum, monkey / nerves, monkey / intestinal tissue, fetal monkey 10 + 100bile canaliculi Hepatitis Mosaic** 100 100bile duct epithelium Hepatitis Mosaic** 10 + 100brain: grey matter cerebellum, monkey / intestinal tissue, fetal monkey 10 + 100 10

brain: white matter cerebellum, monkey / intestinal tissue, fetal monkey 10 + 100 10cANCA granulocytes (EOH), human / liver, monkey 10 10 + 100 1cartilage trachea, fetal monkey 10 10cell nuclei (ANA) HEp-2 cells / liver, monkey 100 + 1000 + 10000 100CENP-F *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100

centromere HEp-2 cells / liver, monkey 100 + 1000 + 10000 100cerebrum gyrus precentralis, monkey 10 + 100 10chondroitin sulfate trachea / cartilage, monkey 10 10 10collagen type VII oesophagus, monkey or tongue, monkey 10 10collagenous connective tissue pancreas, monkey 10 10

colon (epithelial cells) intestinal tissue, fetal monkey 10 10cornea eye, monkey 10 10cyclin I (PCNA) HEp-2 cells / liver, monkey 100 + 1000 + 10000 100cyclin II (mitosin) HEp-2 cells / liver, monkey 100 + 1000 + 10000 100cytoskeleton HEp-2 cells / liver, monkey 100 100 + 1000 + 10000 100

desmosomes oesophagus, monkey or tongue, monkey 10dsDNA *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100dsDNA Crithidia luciliae 10 10elastin stomach, rat / kidney, rat 10endocardium endocardium, monkey / intestinal tissue, fetal monkey 10

endomysium liver, monkey 10 10endoplasmatic reticulum HEp-2 cells / liver, monkey 100 + 1000 + 10000 100endothelial cells lung, monkey 10 10endplates *skeletal muscle, monkey / heart, monkey 100enterocytes intestinal tissue, fetal monkey 10 10

eosinophilic granulocytes granulocytes (EOH) / liver, monkey 10 10 + 100 1epidermal basement membrane oesophagus, monkey or tongue, monkey 10 10eye muscle eye, monkey 10fibrillarin (U3-nRNP) HEp-2 cells / liver, monkey 100 + 1000 + 10000 100filaggrin oesophagus, rat 10 10

ganglion cells ganglion stellatum, monkey / intestinal tissue, fetal monkey 10 10gastric mucosa stomach, monkey 10gastrin-producing cells stomach (antrum), monkey / stomach (corpus), monkey 10 10glandula suprarenalis adrenal gland, monkey 10gliadin *intestinal tissue, fetal monkey / gliadin dots 10 10

glomerular basement membrane (GBM) kidney, monkey 10 10glutamic acid decarboxylase (GAD) cerebellum, monkey / pancreas, monkey 10 + 100 10goblet cells goblet cells (culture) 10 10Golgi apparatus HEp-2 cells / liver, monkey 100 + 1000 + 10000 100hair follicle epidermis, monkey 10 10

heart muscle skeletal muscle, monkey / heart, monkey 100 100heart valves mitral valve, monkey 10 10histones *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100Hu cerebellum, monkey / nerves, monkey / intestinal tissue, fetal monkey 10 + 100 10 + 100hypothalamus nucl. supraopticus & paraventricularis, monkey 10 10

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inner ear inner ear, rat or guinea pig 10 10intercalated discs heart, monkey 100 100intestinal epithelial tissue intestinal tissue, fetal monkey 10 10intrinsic factor *stomach, monkey / intrinsic factor 10 10Jo-1 *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100

keratin oesophagus, monkey or tongue, monkey 10 10keratin, RA-associated (filaggrin) oesophagus, rat 10 10Ku *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100labyrinth inner ear, rat or guinea pig 10 10lacrimal gland (excretory ducts and acini) lacrimal gland, monkey 10 10

laminin epidermis, monkey / lung, monkey / kidney, monkey 10 10lamins HEp-2 cells / liver, monkey 100 + 1000 + 10000 100lipocytes fat tissue, monkey 10 10liver membrane (LMA) Hepatitis Mosaic** 100liver-kidney microsomes (LKM) Hepatitis Mosaic** 100

liver-pancreas antigen (LP) Hepatitis Mosaic** / pancreas, monkey 100liver-specific protein (LSP) Hepatitis Mosaic** 100lymphocytes Lymphocytes 10 + 100 10 + 100lysosomes HEp-2 cells / liver, monkey 100 + 1000 + 10000 100M2 *Hepatitis Mosaic** 100 + 1000 + 10000 100

M3 *Hepatitis Mosaic** 100 + 1000 + 10000 100M4 *Hepatitis Mosaic** 100 + 1000 + 10000 100M5 *Hepatitis Mosaic** 100 + 1000 + 10000 100M6 *Hepatitis Mosaic** 100 + 1000 + 10000 100M7 *Hepatitis Mosaic** 100 + 1000 + 10000 100

M8 *Hepatitis Mosaic** 100 + 1000 + 10000 100M9 *Hepatitis Mosaic** 100 + 1000 + 10000 100medullated nerves cerebellum, monkey / nerves, monkey 10 + 100melanocytes retina, monkey 10 10Mi-1 HEp-2 cells / liver, monkey 100 + 1000 + 10000 100

Mi-2 HEp-2 cells / liver, monkey 100 + 1000 + 10000 100mitochondria (AMA) kidney, rat / stomach, rat / M2 dots / HEp-2 cells 100 + 1000 + 10000 100mouth mucosa mouth mucosa 10 10 10myelin cerebellum, monkey / nerves, monkey 10 + 100myelin-associated glycoprotein (MAG) cerebellum, monkey / nerves, monkey 10 + 100

myeloperoxidase (MPO) granulocytes (EOH), human / liver, monkey 10 10 + 100 1myocardium skeletal muscle, monkey / heart, monkey 100 100myolemma skeletal muscle, monkey / heart, monkey 10 + 100 10 + 100myosin skeletal muscle, monkey / heart, monkey 100 100native collagen pancreas, monkey 10

nerves cerebellum, monkey / nerves, monkey / intestinal tissue, fetal monkey 10 + 100 10 + 100neuroendothelium cerebellum, monkey / nerves, monkey / intestinal tissue, fetal monkey 10 + 100 10 + 100neurofilaments cerebellum, monkey / nerves, monkey / intestinal tissue, fetal monkey 10 + 100 10 + 100NOR HEp-2 cells / liver, monkey 100 + 1000 + 10000 100nRNP HEp-2 cells / liver, monkey 100 + 1000 + 10000 100

ovary ovary, monkey 10 10pANCA granulocytes (EOH), human / liver, monkey 10 10 + 100 1pancreas acini (Crohn’s disease autoantigen) pancreas, monkey 10 10pancreas islets pancreas, monkey (1st step: 18 hours) 10 10pancreas, excretory duct epithelium pancreas, monkey 10 10 10

parathyroid gland parathyroid gland, monkey 10 10parietal cells stomach (corpus), monkey 10 10 10 + 100parotid gland parotid gland, monkey 10 10peripheral nerves cerebellum, monkey / nerves, monkey / intestinal tissue, fetal monkey 10 + 100 10 + 100pituitary gland, anterior lobe pituitary gland, monkey 10 10

Recommended Serum Dilutions for Indirect Immunofluorescence

– Autoimmunity –

Antibodies against Substrate IgA IgG IgM IgAGM

*) In addition to the preferential analysis or as a plausibility check.**) Hepatitis Mosaic: liver, monkey / heart, monkey / HEp-2 cells / liver, rat / kidney, rat / stomach, rat.

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placenta placenta, human 10PM-1 HEp-2 cells / liver, monkey 100 + 1000 + 10000 100proinsulin *pancreas, monkey 10 10prostate prostate, monkey 10proteinase 3 (PR3) granulocytes (EOH), human / liver, monkey 10 10 + 100 1

Purkinje cell cytoplasm (Yo) cerebellum, monkey 10 + 100 10 + 100RANA Raji cells / HEp-2 cells 10 10reticulin intestinal tissue, fetal monkey 10 10 10reticulocytes bone marrow, monkey 10 10retina retina, monkey 10 10

Ri cerebellum, monkey / nerves, monkey / intestinal tissue, fetal monkey 10 + 100 10 + 100ribosomal P-proteins HEp-2 cells / liver, monkey 100 + 1000 + 10000 100ribosomes HEp-2 cells / liver, monkey 100 + 1000 + 10000 100RNA polymerase HEp-2 cells / liver, monkey 100 + 1000 + 10000 100RNA HEp-2 cells / liver, monkey 100 + 1000 + 10000 100

salivary glands (acini and excretory ducts) parotid gland, monkey 10 10sarcolemma skeletal muscle, monkey / heart, monkey 10 + 100 10 + 100Scl-70 HEp-2 cells / liver, monkey 100 + 1000 + 10000 100signal recognition particle (SRP) HEp-2 cells / liver, monkey 100 + 1000 + 10000 100skeletal muscle skeletal muscle, monkey / heart, monkey 100 100

Sm HEp-2 cells / liver, monkey 100 + 1000 + 10000 100smooth muscles (ASMA) stomach, rat / kidney, rat 100 100spermatozoa spermatozoa smear, human 10 10 10spindle fibers HEp-2 cells / liver, monkey 100 + 1000 + 10000 100spleen spleen, monkey 10 + 100

SS-A (Ro) *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100SS-B (La) *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100ssDNA *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100striated muscles skeletal muscle, monkey / heart, monkey 100 100substantia nigra substantia nigra, monkey 10 10 + 100

synovialis joint cartilage, monkey 10 10testis testis, monkey 10 10thrombocytes (bound antibodies) thrombocyte smear – – –thrombocytes (free antibodies) thrombocytes, human 10 10 10thymus thymus, monkey 10 10

thyroglobulin thyroid gland, monkey or struma, human/TG 10 + 100 10thyroid colloid type II thyroid gland, monkey or struma, human 10 10thyroid microsomes thyroid gland, monkey or struma, human 10 + 100 10trachea trachea, monkey 10 10tubular basement membrane kidney, monkey 10 10

U1-nRNP *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100vasopressin-producing cells nucl. supraopticus & paraventricularis, monkey 10 10vestibular organ inner ear, rat or guinea pig 10 10vimentin *HEp-2 cells / liver, monkey 100 + 1000 + 10000 100”xANCA” granulocytes (EOH, acetone, HCHO) / liver, monkey 10 10 + 100 1

Recommended Serum Dilutions for Indirect Immunofluorescence

– Autoimmunity –

Antibodies against Substrate IgA IgG IgM IgAGM

*) In addition to the preferential analysis or as a plausibility check.**) Hepatitis Mosaic: liver, monkey / heart, monkey / HEp-2 cells / liver, rat / kidney, rat / stomach, rat.

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Adenovirus (type 3) 10 + 100 10 + 100 10Afipia felis 100 100 + 1000 10Bartonella henselae 100 + 1000 100Bartonella quintana 100 + 1000 100Bordetella parapertussis 10 + 100 100 + 1000 100 + 1000

Bordetella pertussis 10 + 100 100 + 1000 100 + 1000Borrelia afzelii 100 + 320 + 1000 10Borrelia burgdorferi sensu stricto (strains CH and USA) 100 + 320 + 1000 10Borrelia garinii 100 + 320 + 1000 10Borrelia OspC 10

Borrelia VlsE 100Campylobacter coli 100 100 + 1000 10Campylobacter jejuni 100 100 + 1000 10Candida albicans 100 + 1000 1000 + 10000 100Candida glabrata 100 + 1000 1000 + 10000 100

Candida krusei 100 + 1000 1000 + 10000 100Candida parapsilosis 100 + 1000 1000 + 10000 100Candida tropicalis 100 + 1000 1000 + 10000 100Chlamydia pneumoniae 100 100 + 1000 10Chlamydia trachomatis 100 100 + 320 + 1000 10

CMV 100 100 + 1000 100Coxsackie virus types A7, A9, A16, A24, B1 to B6 10 + 100 100 + 1000 10Dengue virus 10 100 + 1000 10 + 100EBV-CA, EBV-EA 10 + 100 10 + 100 + 1000 10 + 100EBNA 10 + 100

Echinococcus granulosus 100 100 + 320 + 1000 100Echo virus (type 7, 19) 10 + 100 100 + 1000 10Haemophilus influenzae 100 1000 + 10000 10Helicobacter pylori 100 100 + 1000 10HIV-1 10 + 100

HIV-2 10 + 100HHV-6 10 + 100 10HSV-1 10 100 + 1000 + 10000 10HSV-2 10 100 + 1000 + 10000 10Influenza virus type A 10 10 + 100 10

Influenza virus type B 10 10 + 100 10Klebsiella pneumoniae 100 100 100Legionella pneumophila (all serotypes) 100 + 320 + 1000Leishmania 100 320 100Listeria monocytogenes (types 1/2a, 4b) 100 100 + 1000 100

measles virus 10 10 + 100 10mumps virus 10 10 + 100 10Mycoplasma hominis 10 10 + 100 10Mycoplasma pneumoniae 10 10 + 100 10Parainfluenza virus types 1 - 4 10 + 100 10 + 100 + 1000 10

rubella virus 10 + 100 10 + 100 10 + 100RSV 10 10 + 100 + 1000 10Saccharomyces cerevisiae 100 1000 100TBE virus 10 10 + 100 + 1000 10 + 100Toxoplasma gondii 16+64+256 16+64+256+1028... 16+64+256

Treponema pallidum 10 10 + 100 10Ureaplasma urealyticum 10 10 + 100 10VZV 10 10 + 100 10West-Nile virus 10 10 + 100 + 1000 10 + 100Yersinia enterocolitica O:3; O:4; O:6; O:9 10 + 100 100 10 + 100

Antibodies against IgA IgG IgM

Recommended Serum Dilutions for Indirect Immunofluorescence

– Infectious Serology –

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Diagnostically Relevant Systemic Autoantibodies

Ig- AGM A G M SLE: CHRONIC COLLAGENOSIS151 cell nuclei (ANA: IF global testing)156 histones (global testing)1560 histone profile1572 dsDNS-NcX ELISA1572 dsDNA (dsDNA): IF (SLE specific)1574 nucleosomes (SLE specific)1576 single-stranded DNA (ssDNA)1582 U3-nRNP (fibrillarin)1583 RNA polymerase I1584 PM-Scl (PM-1)1585 7-2-RNP (To)1586 4-6-S-RNA1587 nucleolus organizer region (NOR)159 ENA Pool ELISA1591 U1-nRNP1593 Sm (SLE specific)1595 SS-A (Ro)159s SS-A 52 kDa: recombinant159t SS-A 60 kDa: recombinant1597 SS-B (La)1599 Scl-70 (DNA topoisomerase I)1601 cyclin I (PCNA)1603 Sp100 (nuclear dots: PBC)1611 centromeres1611 centromere B protein (recombinant)1621 cardiolipin (AMA M1)162a phosphatidylserine1632 ß-2-glycoprotein 11631 lupus anticoagulant (plasma)**1640 ribosomal P proteins

(SLE specific)194 collagen (global testing)1947 collagen type VII195 elastin196 endothelial cells

Ig- AGM A G M SHARP SYNDROME (MCTD)151 cell nuclei (ANA: IF global testing)1576 single-stranded DNA (ssDNA)1591 U1-nRNP

CIRCULATING IMMUNE COMPLEXES1818 C1q binding test**, ***

Ig- AGM A G M BASIC SPECTRUM151 cell nuclei (ANA: IF global testing)152 ANA profile (differentiation)1572 dsDNS-NcX ELISA1572 dsDNA (dsDNA): IF (SLE specific)1590 ENA ProfilePlus ELISA 1 (nRNP/Sm,

Sm, SS-A, SS-B, Scl-70, Jo-1)1590 ENA ProfilePlus ELISA 2 (rib. P protein,

nRNP/Sm, Sm, SS-A, SS-B, Scl-70, Jo-1, CENP B)1590 SLE Profile ELISA (dsDNA, histones,

rib. P prot., nRNP/Sm, Sm, SS-A, SS-B, Scl-70)162 mitochondria (AMA)171 smooth muscle (ASMA)120 granulocytes: cANCA (M. Wegener)*121 granulocytes: pANCA*1010 autoantibody profile (10 IF substrates)1030 autoantibody profile (30 IF substrates)

Ig- AGM A G M POLYMYOSITIS, DERMATOMYOSITIS151 cell nuclei (ANA: IF global testing)1530 EUROLINE Myositis Profile (Mi-2, Ku,

PM-Scl, Jo-1, PL-7, PL-12, Ro-52)1576 single-stranded DNA (ssDNA)1584 PM-Scl (PM-1)1605 Ku1606 Mi-11607 Mi-21616 signal recognition particle (SRP)1661 Jo-11662 PL-71663 PL-121664 OJ1665 EJ

Ig- AGM A G M OTHER AUTOANTIBODIES1612 centrioles1613 spindle fibres (MSA-1)1614 midbody (MSA-2)1615 chromosome-associated

antigen (MSA-3)1617 centromere F protein (CENP-F)1641 ribosomes1642 Golgi apparatus1643 lysosomes165 cytoskeleton1651 actin1652 vimentin1653 cytokeratin1654 tropomyosin1655 vinculin1656 desmin1659 laminin (basement membranes)

Ig- AGM A G M PROGRESSIVE SYSTEMIC SCLEROSIS151 cell nuclei (ANA: IF global testing)1599 Scl-70 (DNA topoisomerase I)1611 centromeres1611 centromere B protein (recombinant)1582 U3-nRNP (fibrillarin)1583 RNA polymerase I1584 PM-Scl (PM-1)1585 7-2-RNP (To)1586 4-6-S-RNA1587 nucleolus organizer region (NOR)

Ig- AGM A G M (RHEUMATOID) ARTHRITIS151 cell nuclei (ANA: IF global testing)156 histones (global testing)1576 single-stranded DNA (ssDNA)1589 Sa1591 U1-nRNP1604 RANA (rheumathoid arthritis

nuclear antigen)1814 human IgG (rheumatoid factor)194 collagen (global testing)1947 collagen type VII121 granulocytes: pANCA*1219 granulocyte nuclei (GS ANA)148 cartilage1505 cyclic citrullinated peptide

(CCP)1508 filaggrin (RA keratin)1635 serotonin1636 polymyalgia rheumatica factor (PMR)

IMMUNOGLOBULINS:Ig- AGM A G M ANTI-1811 human IgA1813 human IgE1814 human IgG

(rheumatoid factor)1815 human IgM

Ig- AGM A G M WESTERNBLOT ANA TEST1520 ANA differentiation (PM-Scl,

CENP A/B/C, Ku 86 and 72 kDa,M2 74 kDa, RNP 70 kDa, RNP A/C,Sm B/B’/D, SS-A 60 and 52 kDa,SS-B 52, 47, 44 and 43 kDa, ribosomalP protein P0/P1/P2, Scl-70, Jo-1)

FURTHER RHEUMATOID RELEVANTIg- AGM A G M ANALYSES2011 anti-streptolysin2012 anti-streptokinase2013 anti-streptodornase2014 anti-DPNase (anti-NADase)2031 anti-staphylolysin2034 anti-hyaluronidase213 Borrelia burgdorferi2171 Yersinia enterocolitica O:32191 Chlamydia trachomatis6311 CRP

Grey boxes: standard analysis * ANCA diagnostics in acute cases within one hour, at any hour ** Use special procedure for taking sample(s) *** Send frozen sample(s)

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Organ-/Tissue-Specific Autoantibodies

Ig- AGM A G M AUTOANTIBODY PROFILE1030 30 IF substrates (BIOCHIPs)

Ig- AGM A G M THYROID GLAND1011 thyroid microsomes (MAb)1012 thyroid peroxidase1013 thyroglobulin (TAb)1014 thyroid colloid type II1015 TSH receptors (TRAb)1016 T3 (antibodies against T3)1017 T4 (antibodies against T4)

Ig- AGM A G M DIABETES MELLITUS1021 pancreas islets1022 glutamic acid decarboxylase1023 tyrosine phosphatase (IA-2)1024 insulin: human1025 insulin receptors

Ig- AGM A G M (POLY)ENDOCRINOPATHY1011 thyroid microsomes (MAb)1021 pancreas islets104 parathyroid gland1051 adrenal cortex1052 adrenal medulla1053 21-Hydroxylase1061 ovary: theca cells1062 ovary: corpus luteum107 placenta1081 testis: Leydig cells1091 pituitary gland: anterior lobe1092 pituitary gland: posterior lobe110 hypothalamus VPC1361 stomach: parietal cells1361 parietal cells (H+/K+-ATPase; ELISA)

Ig- AGM A G M INFERTILITY1060 ovary: theca cells, corpus luteum,

zona pellucida107 placenta1081 testis:

Leydig cells1086 spermatozoa1091 pituitary gland: anterior lobe1401 prostate1621 cardiolipin (AMA M1)

Ig- AGM A G M NERVOUS SYSTEM1111 brain: grey matter (stiff-man synd.)1022 glutamic acid decarboxylase GAD1027 amphiphysin1111 neuronal antigens EUROLINE

(amphiphysin, CV2, PNMA2 (Ma-2),Ri, Yo, Hu)

1113 Yo (Purkinje cell cytoplasm; PuCA-1)1114 Tr (Purkinje cell cytoplasm; PuCA-2)1115 Ri (neurone nuclei)1116 Hu (neurone nuclei)1117 Ma (neurone nucleoli)1119 CV2 (oligodendrocytes)1121 myelin1122 basic myelin protein (MBP)1123 myelin-assoc. glycoprotein (MAG)1124 myelin of peripheral nerves1153 NMO-IgG (neuromyelitis optica)1154 aquaporin-41155 neurofascin1156 myelin-oligodendrocytes

glycoprotein (MOG)1126 neuroendothelium1127 neurofilaments1128 glial fibrillary acidic protein (GFAP)1129 non-medullated nerves1130 ganglioside profile

(GM1, GM2, GM3, GD1a, GD1b, GT1b, GQ1b)1621 cardiolipin (AMA M1)162a phosphatidylserine1142 phosphatidylcholine1143 phosphatidylethanolamine1144 phosphatidylinositol1145 phosphatidylglycerine1361 stomach: parietal cells151 cell nuclei (ANA: global testing)1572 dsDNA (nDNA): IF (SLE specific)213 Borrelia burgd.: serum CSF

Ig- AGM A G M M. WEGENER, VASCULITIS*120 ANCA Profile ELISA (Proteinase 3,

Myeloperoxidase, elastase,cathepsin G, BPI, lactoferrin)

120 granulocytes: cANCA (M. Wegener)*1201 cANCA: proteinase 3

(PR3-hn-hr)1202 BPI (CAP 57)121 granulocytes: pANCA*1211 pANCA: myeloperoxidase (MPO)1212 pANCA: elastase1213 pANCA: cathepsin G1215 pANCA: lactoferrin151 cell nuclei

(ANA: global testing)195 elastin196 endothelial cells

Ig- AGM A G M EYE1171 cornea1172 retina1173 lens oculi1174 corpus ciliare1175 eye muscles1176 retro bulbar connective tissue1177 tunica choroidea (chronic

chorioretinitis)1011 thyroid microsomes (MAb)1119 CV2 (oligodendrocytes)120 granulocytes: cANCA*151 cell nuclei (ANA: IF global testing)

Ig- AGM A G M IMMUNOHEMATOLOGY1209 granulocyte membrane1221 lymphocytes1226 monocytes1231 thrombocytes: indirect test (free Ab)1232 thrombocytes: direct test (bound Ab)**124 erythrocytes: global testing1361 stomach: parietal cells1361 parietal cells (H+/K+-ATPase; ELISA)1362 intrinsic factor

Ig- AGM A G M SKELETAL MUSCLE, THYMUS,HEART

143 skeletal muscle1431 titin1432 sarcolemma1434 MuSK1435 acetylcholine receptors1436 myosin1437 calcium channel (type N)1438 calcium channel (type PQ)144 thymus146 heart muscle1461 heart: striation1462 heart: intercalated discs1463 heart: myolemma1627 AMA M7 (myocardium specific)

Ig- AGM A G M LIPODYSTROPHY147 lipocytes

Ig- AGM A G M EPIDERMIS1501 epidermis: desmosomes1502 epidermis: basement membrane1502 epidermis: BP180-4X1503 urinary bladder: basement membrane1504 melanocytes1505 herpes gestationis factor1509 epidermal keratin1572 dsDNA (dsDNA): IF (SLE specific)191 endomysium (GSE, M. Duhring)3011 gliadin (GSE, M. Duhring)

Ig- AGM A G M LIVER130 liver (IF global testing, 6 BIOCHIPs)130 EUROLINE Profile autoimmune liver

diseases (AMA M2, 3E (BPO), Sp100,PML, gp210, LC-1, LKM-1,SLA/LP, Ro-52)

1301 liver specific protein (LSP)1302 soluble liver antigen (SLA/LP)1303 asialoglycoprotein receptors1304 liver cell membrane antigen (LMA)1305 bile ducts1306 bile canniculi1307 liver cytosol (LC-1)132 liver kidney microsomes (LKM)1321 LKM 1 ELISA121 granulocytes: pANCA151 cell nuclei (ANA:

IF global testing)1603 Sp100 (nuclear dots: PBC)1608 nuclear membrane (lamin; GP210)1609 few nuclear dots (Coilin; P80)162 mitochondria (AMA)1620 mitochondria (AMA: types M1 to M9)1621 AMA M1 (cardiolipin)1622 AMA M2-3E (PDH + BPO)1624 AMA M4 (sulfite oxidase)1627 AMA M7 (myocardium specific)1629 AMA M9 (glycogen phosphorylase)1651 F-actin1653 cytokeratin 8/18171 smooth muscles (ASMA)

Ig- AGM A G M STOMACH, INTESTINE1361 stomach: parietal cells1361 parietal cells (H+/K+-ATPase; ELISA)1362 intrinsic factor1366 stomach: gastrin (G) cells135 mouth mucosa (M. Crohn, Behçet)1391 pancreas acini (M. Crohn)1392 pancreas secretion (M. Crohn)2841 Saccharomyces cerevisiae (M. Crohn)121 granulocytes: pANCA (UC)138 intestinal mucosa1381 intestinal goblet cells (UC)1382 enterocytes (M. Crohn, UC)191 endomysium (GSE, M. Duhring)191 tissue transglutaminase (GSE, M. D.)192 reticulin3011 gliadin GAF-3X (GSE, M. Duhring)

PANCREATITIS, SJÖGREN’SIg- AGM A G M SYNDROME, EXOCRINE GLANDS139 exocrine pankreas1391 pancreas acini1393 pancreas excretory ducts1401 prostate1406 mamma141 lacrimal gland142 parotid gland1421 parotid gland acini1423 parotid gland excretory ducts151 cell nuclei (ANA: IF global testing)1576 single-stranded DNA (ssDNA)1595 SS-A (Ro)1597 SS-B (La)1604 RANA (rheum. arthritis nuclear antigen)

Ig- AGM A G M ANTIBODIES AGAINST ANIMAL IgG3811 human anti-mouse IgG (HAMA)

IMMUNOHISTOLOGY**,***4125 kidney 4143 skeletal muscle4126 urinary bladder mucosa 4144 myocardium4127 lung 4150 epidermis4131 liver 4199 other ...............4136 stomach ...........................4138 intestinal mucosa

Ig- AGM A G M KIDNEY, LUNG125 kidney (IF global testing)1251 glomerular basement

membrane (GBM)1252 tubular basement membrane (TBM)1271 alveolar basement membrane120 granulocytes: cANCA*121 granulocytes: pANCA*151 cell nuclei (ANA: IF global testing)1572 dsDNA (dsDNA): IF (SLE specific)

ANTIGEN- ANDHORMONE DETERMINATIONS1013 thyroglobulin (TG)1016 free triiodthyronin (FT3)1017 free thyroxin (FT4)1018 thyrotropin (TSH)1019 calcitonin

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Antibodies for Infectious Serology

Ig- AGM A G M BACTERIA A-Z219a Afipia felis*219b Bartonella henselae219d Bartonella quintana2055 Bordetella parapertussis2050 Bordetella pertussis2131 Borrelia afzelii2132 Borrelia burgdorferi

sensu stricto (CH)2133 Borrelia burgdorferi

sensu stricto (USA)2134 Borrelia garinii2092 Campylobacter coli*2091 Campylobacter jejuni*2192 Chlamydia pneumoniae2193 Chlamydia psittaci*2191 Chlamydia trachomatis2070 Haemophilus influenzae*2080 Helicobacter pylori2101 Klebsiella pneumoniae*216a Legionella bozemanii*2167 Legionella dumoffii*2166 Legionella gormanii*2165 Legionella jordanis*2168 Legionella longbeachae2169 Legionella micdadei*2150 Legionella pneumophila

Serotypes 1-14: ..................2140 Listeria monocytogenes*

1/2a 4b2201 Mycoplasma hominis2202 Mycoplasma

pneumoniae2111 Treponema pallidum2205 Ureaplasma urealyticum2170 Yersinia enterocolitica*

O:3 O:4O:6 O:9

Ig- AGM A G M PARASITES A-Z2320 Echinococcus granulosus2231 Leishmania donovani2410 Toxoplasma gondii

Avidity determination

Ig- AGM A G M VIRUSES A-Z2680 Adenovirus type 3293a Chikungunya virus2730 Coxsackievirus type:

B1 B2 B3 B4B5 B6 A7 A9A16 A24

2570 CytomegalovirusAvidity determination

266 Dengue virus type1 2 3 4

275a Echovirus type 72791 EBV capsid Ag (EBV-CA)

Avidity determination2795 EBV early Ag (EBV-EA)2793 EBV nuclear Ag (EBNA)278 Hantavirus type

Hantaan Puumala SeoulSin Nombre Dobrava Saaremaa

2531 Herpes simplex 1 (HSV-1)2532 Herpes simplex 2 (HSV-2)2536 Hum. herpes 6 virus (HHV-6)2691 Influenza virus type A

H1N1 H3N22692 Influenza virus type B2610 Measles virus2630 Mumps virus2720 Parainfluenza virus type:

1 2 3 42670 Resp. syncytial virus (RSV)2590 Rubella virus

Avidity determination2661 TBE virus2650 Varicella-zoster virus

Avidity determination2662 West-Nile virus

Avidity determination2665 Yellow fever virus

Ig- AGM A G M FUNGI A-Z286 Candida

albicans glabrata* krusei*parapsilosis* tropicalis*

2841 Saccharomyces cerevisiae

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Grey: standard analyses *) Currently not available as IVD in the EC

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Antibodies for Allergology

Grey: standard analyses

GLOBAL TEST3840 Determination of total IgE

INHALATION3110 Inhalation Profile 1 (gx, t3, w6, d1, e1, e2, m2)3110 Inhalation Profile 2 (g1, g3, g6, g12, t2, t3, t4, t7,

w1, w6, w9, d1, d2, e1, e2, e3, m1, m2, m3, m6)3111 Pediatrics (g6, g12, t2, t3, t4, w6, w8, w9, d1, d2,

e1, e2, e3, e6, e82, e84, m1, m2, m3, m6)3120 gx Grass mix (g6/g12)3121 g1 Sweet vernal grass3123 g3 Cocksfoot3126 g6 Timothy grass3132 g12 Cultivated rye3152 t2 Alder3153 t3 Birch3154 t4 Hazelnut3157 t7 Oak3201 w1 Common ragweed3206 w6 Mugwort3208 w8 Dandelion3209 w9 Plantain3241 d1 House dust mite 1

(Dermatophagoides pteronyssinus)3242 d2 House dust mite 1

(Dermatophagoides farinae)3261 e1 Cat3262 e2 Dog3263 e3 Horse3266 e6 Guinea pig3282 e82 Rabbit3284 e84 Hamster3321 m1 Penicillium notatum3322 m2 Cladosporium herbarum3323 m3 Aspergillus fumigatus3326 m6 Alternaria alternata

FOOD3410 Food Profile 1 (f1, f2, f3, f4, f13, f14, f17)3410 Food Profile 2 (f1, f75, f2, f45, f4, f5, f9, f14, f13,

f17, f20, f49, f237, f84, f85, f31, f25, f35, f3, f23)3421 f1 Egg white3425 f75 Egg yolk3442 f2 Milk3531 f45 Yeast3522 f4 Wheat flour3523 f5 Rye flour3527 f9 Rice3544 f14 Soja bean3543 f13 Peanut3547 f17 Hazelnut3550 f20 Almond3569 f49 Apple3596 f237 Apricot3573 f84 Kiwi3574 f85 Celery3563 f31 Carrot3562 f25 Tomato3565 f35 Potato3461 f3 Codfish3462 f23 Crab

ATOPY3710 Atopy Profile (g6, g12, t3, w6, e1, e2, e3, d1, m2,

m6, f1, f2, f3, f4, f9, f14, f17, f31, f35, f49)3126 g6 Timothy grass3132 g12 Cultivated rye3153 t3 Birch3206 w6 Mugwort3261 e1 Cat3262 e2 Dog3263 e3 Horse3241 d1 House dust mite 1 (Derm. pteronyssinus)3322 m2 Cladosporium herbarum3326 m6 Alternaria alternata3421 f1 Egg white3442 f2 Milk3461 f3 Codfish3522 f4 Wheat flour3527 f9 Rice3544 f14 Soja bean3547 f17 Hazelnut3563 f31 Carrot3565 f35 Potato3569 f49 Apple

INSECT VENOMS3731 i1 Honey bee venom3733 i3 Wasp venom

LATEX AND LATEX-ASSOCIATEDALLERGIES

3760 Latex Plus (k82, k81, f92, f96, f35, f84)3774 k82 Latex3773 k81 Ficus spp.3579 f92 Banana3582 f96 Avocado3565 f35 Potato3573 f84 Kiwi

POLLEN-ASSOCIATED FOOD ALLERGIES3711 Profile Pollen-Food Cross Reactions

(gx, t3, w6, f4, f5, f13, f17, f20, f48, f89, f271, f275,f44, f49, f348, f237, f328, f31, f35, f85)

3120 gx Grass mix (g6/g12)3153 t3 Birch3206 w6 Mugwort3522 f4 Wheat3523 f5 Rye3543 f13 Peanut3547 f17 Hazelnut3550 f20 Almond3568 f48 Onion3672 f89 Mustard3652 f271 Anise3656 f275 Lovage3566 f44 Strawberry3569 f49 Apple3629 f348 Lychee3596 f237 Apricot3624 f328 Fig3563 f31 Carrot3565 f35 Potato3574 f85 Celery

DOMESTIC ANIMALS3260 Dom. Animal Profile (e1, e2, e3, e6, e82, e84, e71)3261 e1 Cat3262 e2 Dog3263 e3 Horse3266 e6 Guinea pig3282 e82 Rabbit3284 e84 Hamster3271 e71 Mouse epithelium

Allercoat™ 6 System: Antibodies of class IgE against 600 differentallergens of the areas animal allergens, environmental allergens,food, grasses, herbal and flower pollen, house dust, insects, mites,moulds, parasites, pharmaceutical drugs, trees.

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EUROIMMUN Microplate ELISA

Principle of the Test

• Polystyrene microplate strips coated with purified, biochemically characterizedantigens are used as solid phase containing bound antigens.

• If the sample is positive, specific antibodies in the diluted serum sample attach tothe antigens coupled to the solid phase.

• In a second step, the attached antibodies are detected with peroxidase-labelledanti-human antibodies.

• In a third step, the bound antibodies are made visible using a chromogen/substrate solution which is capable of promoting a color reaction. The intensityof the color produced is proportional to the concentration of antibodies in theserum sample.

• Monospecific ELISA (enzyme immunoassays with a single antigen) provide aquantitative in vitro assay for the detection of antibodies.

• “Profile ELISA” provide a semiquantitative in vitro assay for the detection ofdifferent antibodies on a single microplate strip.

• The solid phase of “Pool ELISA” is coated with an antigen mixture for the semi-quantitative detection of antibodies whose specificity must be subsequentlyinvestigated by monospecific assays.

Reliable and Economical Calibration/Evaluation

• In the case of a quantitative ELISA, calibration is performed using three cali-bration sera.

Calibration serum 1: upper limit of the measurement range

Calibration serum 2: upper limit of the normal range (cut-off value)

Calibration serum 3: negative

• Only three wells are required for calibration, followed by serum samples. Thereis no need to incubate blank values or duplicate determinations.

• Semiquantitative ELISA are performed using only one calibrator.

• The calibration is performed in relative units per milliliter (RU/ml) or, if aninternational reference serum exists, in international units per milliliter (IU/ml).

• Each test can be optionally performed using a positive or negative control serumincluded in the test kit. Kit-specific reference ranges are provided for eachcalibrator and control serum.

• All calibrations can be easily performed with the usual ELISA software.

Easy, Quick and Economical Handling

• Microplate strips containing break-off wells (except Profile ELISA), each markedwith an antigen abbreviation to avoid confusion of wells.

• Reagents ready for use (wash buffer: concentrate). Reagents are color-coded toensure positive identification.

dark red: calibration serum 1 orange: anti-human IgA POD-conj.

red: calibration serum 2 green: anti-human IgG POD-conj.

light red: calibration serum 3 red: anti-human IgM POD-conj.

dark blue: pos. control serum turquoise: anti-human IgGM POD-conj.

green: neg. control serum yellow: anti-human IgAGM POD-conj.

light blue: sample buffer

• The sample buffer for infectious serology ELISA (detection of antibodies of classIgM) already contains an IgG/RF absorbent.

• Several tests can be combined on one and the same microplate, since the incu-bation times (30 min; 30 min; 15 min) are identical for all ELISA. Incubation atroom temperature.

• Compatible with all commercial washer and reader systems.

antigen-coatedmicroplate well

specific humanantibody

POD-labelledanti-human antibody

PODsubstrate

stain

chromogen

POD

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0 25 50 75 100

Determination of Low-Avidity Antibodies

• An alternative principle for the serological diagnosis of fresh infections has beenestablished by investigating the antibody avidity.

• The first reaction of the immune system following an infection is the formation oflow-avidity antibodies. As the infection proceeds, increasingly antigen-adaptedIgG is formed, and avidity grows. As long as high-avidity IgG is not yet detectedin the serum, it can be assumed that the infection is still in an early stage.

• To identify low-avidity antibodies in a patient’s serum, two microplate ELISA areperformed in parallel: one test is carried out in the conventional way, the otherone includes urea treatment between incubations with patient’s serum and per-oxidase-labelled anti-human IgG, resulting in the detachment of low-avidityantibodies from the antigens.

• Low-avidity antibodies are present if the ELISA extinction is significantly reducedby urea treatment. For an objective interpretation, the relative avidity index (RAI)can be calculated out of the measured values with and without urea incubation.

• Serum dilution 1 : 100, conjugate class anti-human IgG, POD-labelled.

• 3-point calibration, quantitative (IgG).

• The following test kits for avidity determination are available: Toxoplasma gondii,CMV, rubella virus, VZV, West-Nile virus, EBV-CA.

Avidity of antibodies against EBV-CA (IgG)

Relative Avidity Index (RAI) in %

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Primary Infection

Previous Infection

EUROIMMUN Microplate ELISA

Antibody Determination in CSF

• Indication: local infections of the brain.

• CSF dilution 1 : 2, serum dilution 1 : 401. Conjugate classes anti-human IgG orIgM, POD-labelled.

• Easy to conduct: ready-for-use reagents.

• 4-point calibration, quantitative. Identical incubation conditions and times (roomtemperature; 60 min / 60 min / 15 min): all EUROIMMUN ELISA for CSF dia-gnostics can be combined without difficulty on one and the same microplate.

• The antibody concentration in the patient’s serum is determined in parallel to theantibody concentration in CSF on one and the same microplate. The CSF/serumquotient CSQpath.-spec. is calculated from both measured values.

• An intrathecal synthesis of specific antibodies is present if the CSF/serumquotient of the specific antibodies CSQpath.-spec. is significantly higher than theCSF/serum quotient of the whole IgG (CSQtotal) or if necessary the CSQlim.. Therelation of both values indicates the relative CSF/serum quotient CSQrel.(synonym: antibody specificity index, ASI).

• Interpretation of results (according to the recommendations of Prof. Reiber):

CSQrel. < 1,3: standard range

CSQrel. 1,3 – 1,5: borderline range

CSQrel. > 1,5: Indication of pathogen-specific antibody production in the CNS

• For the automatic calculation of the CSQrel. EUROIMMUN provides a specificExcel table free of charge.

• Highest sensitivity, specificity and reproducibility. Antibody concentrations in theserum and CSF are determined within the linear range of the test.

• The following test kits for CSF diagnostics are available: Borrelia burgdorferi,Toxoplasma gondii, HSV-1, HSV-2, HSV-1/2 Pool, CMV, rubella virus, measlesvirus, mumps virus, VZV, TBE, EBV-CA.

• All test systems for CSF diagnostics can also be used only for serology.

• Perfectly adapted for the automated incubation in incubation devices.Reference range ofnormal values, intactblood-CSF barrier

Dysfunction of theblood-CSF barrier, noIg production in theCNS

Dysfunction of theblood-CSF barrier,additional Igproduction in the CNS

Intact blood-CSFbarrier, Ig productionin the CNS

Mistakes duringpreparation of thesera or the analyticalsteps

0.001

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CFS/serum quotient diagram according to Reiberand Lange (1991)

ELISA incubation scheme

Table-based evaluation of the CSQrel.

CSF calibrators CSF serumC SD-AC

1 2 3 4 5 6

AAC 3C

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BBC 3S

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H2S 6S

104:1 104:1

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ELISA Automation Using the EUROIMMUN Analyzer I

EUROIMMUN Analyzer I: The New Automated ELISA System forMicrotiter Plates

• Automation of all EUROIMMUN ELISA, including the allergy system Allercoat™6.

• Over 900 validated parameters available (60 autoantibody, 100 infection and650 allergy parameters).

• Up to 7 microtiter plates can be loaded.

• Unusually short loading time.

• Reloading function for patient samples, microtiter plates, reagents and disposabletips.

• "Walk-away function" – fully automated from the start to the end of processingfollowing loading.

• Own processor, independent of external system, minimises risk of systemcrashes.

• Bidirectional online connection to laboratory computer system.

Modular System: A Highly Sophisticated Solution

• High convenience through barcode identification of samples and reagents:automatic scanning when racks are inserted, quality control certificate via 2Dhand barcode scanner.

• Dilution area: 288 dilution positions (Deepwell, 2 ml).

• Liquid level detection (capacitive), multi-shot (dispensing) mode, automatic tipdetection, clot detection.

• Pipetting possible during plate transport due to separation of transport andpipetting unit.

• 4 incubators with heating and shaking function, 4 incubators at roomtemperature.

• Standard Windows 2000 software available in several languages: open system,all relevant statistical functions included.

• Memory function for tips and dilution plates: allows full use of the dilution plates,no reloading of tips required.

A Convincing and Reliable Package: EUROIMMUN Analyzer I,EUROIMMUN ELISA, EUROIMMUN Service

• Comprehensive test system validation for the EUROIMMUN Analyzer I: all para-meters validated in accordance with the 98/79/EC directive and based onEN ISO 13485:2003.

• All ELISA test systems are manufactured according to the European QualityStandards (IVD).

• National and international conformity (standardisation): CE, IVD, FDA andCMD/CAS.

• Programming and setup of automated system, including introduction into thesystem and customer training, performed by qualified personnel.

• Reliable and fast delivery of disposable materials.

• Connection to in-house computer system via communication protocol ASTM.

• Maintenance contract with EUROIMMUN if desired.

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Incubate: 30 min

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microplate wells coatedwith antigens

dilutedsamples

enzymeconjugate

chromogen/substrate solution

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Pipette: 100 µl per well

Incubate: 30 min

Evaluate: photometric measurement ata wavelength of 450 nm

Wash: 300 µl wash bufferper well

Pipette: 100 µl per well

Incubate: 15 min

Pipette: 100 µl per well

stopsolution

Incubating the Microplate ELISA

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AP

membrane coatedwith antigen

specific humanantibody

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antibody

EUROASSAY: A New Technique for the Determination of Antibody Profiles

Principle of the Test

• Membrane strips coated with thin parallel lines of several purified, biochemicallycharacterized antigens are used as solid phase. The membrane strips are fixed asBIOCHIPs in the fields of microscope slides.

• If the sample is positive, specific antibodies in the diluted serum sample attach tothe antigens coupled to the solid phase.

• In a second incubation step, the attached antibodies react with AP-labelled anti-human antibodies.

• In a third step, the bound antibodies are stained with a chromogen/substratesolution which is capable of promoting a color reaction. An intense dark band atthe line of the corresponding antigen appears if the serum sample containsspecific antibodies.

• The microscope slides are incubated using the TITERPLANE™ Technique:samples and reagents are applied to the reaction areas of a reagent tray. Theslides are then placed into the recesses of the reagent tray, where all test stripsof one slide come into contact with the liquids, and the individual reactions beginsimultaneously.

• Depending on the spectrum of antigens used, it is possible to analyze severalantibodies next to each other and simultaneously under identical conditions.

Easy Handling

• Several serum samples can be analyzed simultaneously on one and the sameslide.

• Total time for performing the EUROASSAY test is about 100 minutes. During thewashing procedure, reagents for the next incubation step can be applied toreagent trays.

• All incubation steps proceed at room temperature. Shaking the slides togetherwith the reagent tray on a circulatory shaker ensures the best possible sensitivity.

• Low reagent consumption. Only 50 µl each of diluted serum and reagent areneeded per test field.

• Reagents ready for use (wash buffer: concentrate).

Reliable and Simple Evaluation

• Since results are evaluated visually, there is no investment required forphotometers, etc.

• The antigen bands are located at exactly defined positions, which means thatevaluation of the test is much simpler than for Westernblots.

• Correct completion of the individual incubation steps in each test field isindicated by staining of the control band.

• Positive and negative results can be easily and reliably differentiated from eachother. The intensity of the antigen bands correlates with the antibody titer.

• The antigens used are highly pure, mostly isolated by affinity chromatography.The membrane strips do not contain any superfluous proteins which might causeunspecific positive results.

• The incubated microscope slides can be stored for long periods. Results can beeasily documented.

EUROASSAY Anti-ENA ProfilePlus: detection ofantibodies against SS-A and SS-B in a case ofSjögren’s syndrome.

Controlband

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Wash: 5 s flush15 min cuvette

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reagent traymembrane strips

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washbuffer

enzyme conjugate

chromogen/substratesolution

washbuffer

Pipette: 50 µl per field

Pipette: 50 µl per field

Incubate: 30 min shaking on acirculatory shaker(300 rpm)

Wash: 5 s flush15 min cuvette

Pipette: 50 µl per field

Incubate: 10 min shaking on acirculatory shaker(300 rpm)

Wash: flush with deionizedor distilled water,air dry

Evaluate: visual assessmentof color intensity

Incubating the EUROASSAY (TITERPLANE™ Technique)

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Principle of the Test

• Membrane strips coated with thin parallel lines of several purified, biochemicallycharacterized antigens are used as solid phase. The membranes are fixed asBIOCHIPs onto synthetic foil.

• If the sample is positive, specific antibodies in the diluted serum sample attachto the antigens coupled to the solid phase.

• In a second incubation step, the attached antibodies react with alkaline-phosphatase-labelled anti-human antibodies.

• In a third step, the bound antibodies are stained with a chromogen/substratesolution which is capable of promoting a color reaction. An intense dark band atthe line of the corresponding antigen appears if the serum sample containsspecific antibodies.

• Depending on the spectrum of antigens used, it is possible to analyze severalantibodies next to each other and simultaneously under identical conditions.

Easy Handling, Reliable and Simple Evaluation

• A separate membrane strip is incubated for each serum sample.

• Total time for performing the analysis is about 105 minutes.

• The incubation can be automated.

• All incubation steps proceed at room temperature on a rocking platform. Therequired incubation tray is supplied in each test kit.

• Prior to first incubation step, the EUROLINE test strips are treated for 5 minuteswith sample buffer*.

• The results are evaluated visually: no investment for photometers or otherequipment is necessary.

• The antigen bands are located at exactly defined positions, which means that theevaluation of the test is much simpler than for Westernblots.

• Correct completion of the individual incubation steps is indicated by staining ofthe control band on each EUROLINE test strip.

• Positive and negative results can be easily and reliable differentiated from eachother. The intensity of the antigen bands correlates with the antibody titer.

• The antigens used are highly pure, mostly isolated by affinity chomatography.The membrane strips do not contain any superfluous proteins which might causeunspecific positive results.

• The incubated EUROLINE test strips can be stored for long periods. Results canbe easily documented.

• The program EUROLineScan from EUROIMMUN has been developed to enablequantitative evaluation of EUROLINE test strips, to facilitate management of data,and to provide detailed documentation of results. First, the incubated EUROLINEtest strips are scanned using a flatbed scanner. EUROLineScan recognizes theposition of the strips, even if they have been placed inexactly, identifies thebands, and measures their intensity. The results are then saved together with theimage data. A separate results sheet can be produced for each patient.

*) only applicable for some EUROLINE test kits

stain

APsubstrate chromogen

AP

membrane coatedwith antigen

specific humanantibody

AP-labelledanti-human

antibody

The EUROLINE: A New Technique for Extensive Antibody Profiles

nRNP/Sm

Sm

SS-A/Ro-52

SS-B

Scl-70

PM-Scl

Jo-1

CENP B

PCNA

dsDNA/nucleos.

histones

rib. P proteins

AMA M2

Incubated EUROLINE ANA-Profile 3 test strips.

control

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

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wash buffer

enzyme conjugate

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Pipette: 1.5 ml per channel

Wash: 1.5 ml buffer,5 min incubation,aspirate off

incubation channel

sample buffer

Incubate: 30 min shaking on arocking platform

Pipette: 1.5 ml per channel

Incubate: 30 min shaking on arocking platform

Incubate: 10 min shaking on arocking platform

Wash: 1.5 ml buffer,5 min incubation,aspirate off

Pipette: 1.5 ml per channel

Wash: rinse with distilledwater, aspirate off

Evaluate: visual assessment of bands

wash buffer

Incubating the EUROLINE

*) only applicable for some EUROLINE test kits

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EUROBlotCamera EUROBlotScanner

Westernblot/EUROLINE-WB: Reliable Differentiation of Antibodies Present

Principle of the Test

• Membrane strips containing electrophoretically separated antigen extracts areused as solid phase. The position of the proteins depends on their respectivemolecular weights.

• If the sample is positive, specific antibodies in the diluted serum sample attach tothe antigens coupled to the membrane.

• In a second incubation step, the attached antibodies react with AP-labelled anti-human antibodies.

• In a third step, the bound antibodies are stained with a chromogen/substratesolution which is capable of promoting a color reaction. An intense dark band atthe line of the corresponding antigen appears if the serum sample containsspecific antibodies.

• Evaluating the band patterns on the incubated membrane strips involvesdifferentiating non-specific from specific antibodies. The number and intensity ofthe specific bands is decisive for the result “positive/negative“.

• Antibodies against all antigens contained in the membrane strip can be analyzedsimultaneously in one single test procedure.

stain

AP

substratechromogen

AP

membrane coatedwith antigen

specific humanantibody

AP-labelledanti-human

antibody

Reliable Evaluation and High Diagnostic Significance

• A separate membrane strip is incubated for each serum sample.

• Total time for performing the Westernblot test is about 115 minutes.

• The bands are assigned according to a lot-specific evaluation matrix provided. Aseparate lot is issued for each electrophoresis gel, helping to avoid errors in theassignment of the bands.

• Every test kit contains a membrane strip of the same lot incubated with a positivereference serum. Therefore, there is no need to incubate a positive control serum.

• The membrane strips are pre-numbered to prevent confusion. Laborious labellingis not necessary.

• Correct completion of the individual incubation steps for each membrane strip isindicated by staining of the control band at the bottom of the strip.

• EUROLINE-WB is a combination of westernblot and line blot techniques. Proteinsfrom a whole antigen extract are electrophoretically separated according tomolecular mass and transferred onto a nitrocellulose membrane. Highly purifiednative or recombinant antigens are then printed as lines onto the westernblotstrips (EUROLINE membrane chip).

VlsE antigen on EURO-LINE membrane chip

Alignment bar

Control band

Automatic evaluation of results using EUROLineScan

• For all EUROIMMUN blot systems: EUROLINE, EUROLINE-WB, Westernblot.

• For all areas: autoimmune diagnostics, infectious serology and allergy.

• EUROBlotCamera: digitalisation of strips while in the incubation tray.

• EUROBlotScanner: digitalisation of strips using flatbed scanner.

• Fully automated identification, quantitation and assignment of bands.

• Option to modify results (changes are automatically documented).

• Complete results obtained just a few minutes after finishing the incubation.

• Fully automated administration and documentation of extensive individual data.

• Electronic archiving of all images and data (avoids the need to store potentiallyinfectious blot strips).

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diluted samples

universal buffer

enzyme conjugate

chromogen/substrate solution

Pipette: 1.5 ml per channel

Pipette: 1.5 ml per channel

Wash: 1.5 ml buffer,5 min incubation,aspirate off

incubation channel

universal buffer

Incubate: 30 min shaking on arocking platform

Pipette: 1.5 ml per channel

Incubate: 30 min shaking on arocking platform

Incubate: 10 min shaking on arocking platform

Wash: 1.5 ml buffer,5 min incubation,aspirate off

Pipette: 1.5 ml per channel

Wash: rinse with distilledwater, aspirate off

Evaluate: visual assessment

universal buffer

Incubating the Westernblot/EUROLINE-WB

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125I125I

125I

EUROIMMUN Radioimmunoassays (RIA/IRMA)

Test principle RIA (precipitation techniques)

• In the first incubation step patient sera are incubated with 125I-labelled antigen inpolystyrene tubes. Any specific antibodies in the sera bind to the antigen.

• In the second incubation step the antigen-antibody complexes are precipitatedusing a precipitation agent.

• The precipitate is washed with buffer. After centrifugation and decanting of thesupernatant, the radioactivity in the precipitate is counted using a gammacounter. The intensity of the radioactivity is proportional to the concentration ofspecific antibody in the patient serum.

• The antibody concentration is evaluated quantitatively using a calibration curve.

Test principle RIA (coated tubes)

• RIA tests (coated tubes) are competitive ligand assays for antibody and antigendeterminations.

• The intensity of radioactive radiation is inversely proportional to theconcentration of specific antibodies or antigens in the sample.

• The quantitative evaluation of the antigen/antibody concentration is carried outusing a calibration curve.

Test principle IRMA (antigen determination)

• With this test principle, monoclonal antibodies which are bound directly orindirectly to the inner wall of polystyrene tubes are used.

• During the first incubation step, the patient sera to be investigated are incubatedwith the monoclonal 125I-labelled antibodies in the coated tubes.

• The antigen in the sample is bound by the immobilised antibodies and by the 125I-labelled antibodies. This results in a solid-phase bound sandwich complex.

• The unbound 125I-labelled antibodies are removed by washing and subsequentlydecanting. The intensity of radioactive radiation is proportional to the concen-tration of antigens in the patient serum.

• The quantitative evaluation of the antigen concentration is carried out using acalibration curve.

Simple and economical handling, reliable analysis

• Simple test procedure.

• Synchronous processing of samples, including different tests in parallel.

• Ready-to-use reagents (possible exceptions: tracer, precipitation reagents).

• Different test formats for small and large sample series.

• Because of the large measurement range of EUROIMMUN RIA, furthermeasurements with other sample dilutions are generally not necessary.

• Simple evaluation of test results.

• Each test can be optionally evaluated with controls which are supplied in the testkit. Test kit-specific reference ranges are given for all controls.

• EUROIMMUN radioimmunoassays show the following analytical characteristics:

– High analytical specificity.

– High detection sensitivity.

– High clinical sensitivity and specificity.

– Good reproducibility.

precipitationagent

specific human antibodyradioactively

labelledantigen

(“tracer”)

radioactivelylabelledantibody

analyte

antibody

solid phase(tube surface)

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EUROIMMUN PRODUCTS FOR THE DETERMINATION OF AUTOANTIBODIES

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Autoantibodies against Cell Nuclei (ANA)

Indirect Immunofluorescence Test: EUROPLUS™ ANA Mosaic 20

• Screening test for the detection of antibodies against cell nuclei (ANA).

• Indications: rheumatic diseases.

• Initial dilution 1 : 100; conjugate class anti-human IgG, FITC-labelled.

• Using HEp-2 cells many antibodies against cell nuclei can be analyzed, e.g. anti-bodies against DNA, histones, RNA, nRNP, Sm, SS-A, SS-B, nuclear dots, centro-meres, nuclear membrane, nucleoli (PM-Scl, fibrillarin, RNA polymerase I, NOR),Scl-70, cyclin I and II, spindle fibers, midbody, centrioles.

• In addition, cytoplasmic autoantibodies are identified with HEp-2 cells: antibodiesagainst ribosomes, Jo-1, mitochondria, Golgi apparatus, actin etc.

• The primate liver permits the verification of results between both substrates, makesthe pre-differentiation of a large number of ANA possible, and helps to establishtiter levels. Moreover, the primate liver often contains additional antigens, allowingthe identification of further autoantibodies: antibodies against LMA, LSP, endo-mysium, bile ducts and endothelium cells, as well as cANCA und pANCA.

• The EUROPLUS™ system is a monospecific test that can be used to confirm thepresence of autoantibodies against cell nuclei and cytoplasm with one and thesame test kit. The following antigens are currently available as EUROPLUS™BIOCHIPs: SS-A, SS-B, nRNP/Sm, Sm, Scl-70, Jo-1, ribosomal P-proteins.

Order No. FormatsFA 1510-####-20 G page 129

Order No. FormatsFA 1522-#### G page 130

Order No. FormatsDA 1590-####-1 G page 75

EUROASSAY: Anti-ENA ProfilePlus

• Differentiation of anti-nuclear antibodies (ANA).

• Indications: rheumatic diseases.

• Serum dilution 1 : 100; conjugate class anti-human IgG, AP-labelled.

• 6 relevant anti-nuclear antibodies against “extractable nuclear antigens“ (ENA)can be detected simultaneously and monospecifically: antibodies againstnRNP/Sm, Sm, SS-A, SS-B, Scl-70, Jo-1.

• Native antigens, purified by affinity chromatography.

• On request EUROASSAY can be produced with special antigen combinations, forexample, with dsDNA, histones, nucleosomes, PM-Scl, nRNP/Sm, Sm, SS-A,Ro-52, SS-B, Scl-70, Jo-1, ribosomal P proteins, centromere protein B, M2, M4,M9, SLA/LP, LC-1, LKM-1.

HEp-2010: antibodies against spindle fibers.

Incubated EUROASSAY Anti-ENA ProfilePlus.

Indirect Immunfluorescence Test: New Cell Line from EURO-IMMUN, HEp-20-10

• Screening test for detection of antibodies against cell nuclei.

• Indications: rheumatic diseases.

• Initial dilution 1 : 100; conjugate class anti-human IgG, FITC-labelled.

• Compared to standard HEp-2 cells, HEp-20-10 cells demonstrate 10-fold moremitotic cells. Antibodies against mitotic-specific structures (centromeres, spindlefibers, midbody, centrioles, NOR) can be more easily identified than with con-ventional preparations.

• At the same time, the cell line HEp-20-10 offers the full antigen spectrum for cellnuclei antibody diagnostics.

• The BIOCHIP with HEp-20-10 can be supplemented with additional substrates, forexample, primate liver (ANA; Order No. FA 1512-####-1 G) as well as rat kidneyand rat stomach (Order No. FA 1802-####-3 G).

EUROPLUS™ ANA Mosaic 20 (HEp-2 cells, pri-mate liver, SS-A+SS-B BIOCHIPs, rib. P-prot.+Jo-1BIOCHIPs: antibodies against SS-A/SS-B.

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snRNP/SmSm

SS-BScl-70

Jo-1

Sm B/B’

Rib.-P

RNP A

RNP 70Ku

CENP B

Ro-52

SS-A

PM-Scl

SS-A

CENP B

AMA M2

Ro-52

PCNA

Mi-2

Ku

Jo-1

PL-12

PL-7

Ro-52

PM-Scl

Incubated EUROLINE ANA Profile 3.

EUROLINE: ANA Profile 3

• Differentiation of antibodies against cell nuclei (ANA).

• Indications: Sharp syndrome (MCTD), systemic lupus erythematosus, Sjögren’ssyndrome, progressive systemic sclerosis, poly/dermatomyositis, PBC.

• Serum dilution 1 : 100; conjugate class anti-human IgG, AP-labelled.

• With the EUROLINE ANA-Profile 3, fifteen autoantibodies can be determined: anti-bodies against nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Scl-70, PM-Scl, Jo-1, centro-mere protein B, PCNA, dsDNA, nucleosomes, histones, ribosomal P-proteins,AMA M2.

• Antibodies against SS-A are characteristic markers for SLE and Sjögren’ssyndrome. In contrast, antibodies against Ro-52 also occur in patients with otherautoimmune diseases.

• Native antigens, purified by affinity chromatography (exception: centromereprotein B, PM-Scl, Ro-52, PCNA).

• Further antigen combinations: page 76.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

EUROLINE-WB: HEp-2 Cell Antigens plus SS-A, Ro-52 and CENP B

• Differentiation of antibodies against cell-nuclear and cytoplasmic antigens.

• Indications: Sharp syndrome (MCTD), systemic lupus erythematosus, Sjögren’ssyndrome, progressive systemic sclerosis, poly/dermatomyositis, PBC.

• EUROLINE-WB is a combination of westernblot and line blot techniques. Proteinsfrom a whole antigen extract of HEp-2 cells are electrophoretically separatedaccording to molecular mass and transferred onto a nitrocellulose membrane. Amembrane chip coated with highly purified native SS-A, recombinant Ro-52 andrecombinant CENP B is then added to the westernblot strips.

• Antibodies against SS-A are characteristic markers for SLE and Sjögren’ssyndrome. In contrast, antibodies against Ro-52 also occur in patients with otherautoimmune diseases. EUROLINE-WB contains both antigens next to each otherat defined positions, in addition to the complete HEp-2 antigen spectrum of theWesternblot. The use of native SS-A increases the sensitivity, since 37% of anti-bodies against SS-A do not show any reaction with the denatured antigen fromthe Westernblot

• Serum dilution 1 : 50, conjugate class anti-human IgG, AP-labelled.

• Antigens: SDS extract from HEp-2 cells (whole antigen), highly purified nativeSS-A from calf thymus, recombinant Ro-52 and CENP B.

Order No. FormatsDL 1590-1601-3 G page 76

Order No. FormatsDW 1520-1601-3 G page 78

Incubated EUROLINE-WB HEp-2 Cell Antigens plusSS-A, Ro-52 and CENP B.

Autoantibodies against Cell Nuclei (ANA)

histones

dsDNAnucleos.

rib. P-prot.

control

native SS-Arec. Ro-52

rec. CENP B

EUROLINE: Myositis Profile

• Differentiation of myositis-associated antibodies against cell-nuclear andcytoplasmic antigens.

• Indications: poly/dermatomyositis.

• Serum dilution 1 : 100, conjugate class anti-human IgG, AP-labelled.

• With the EUROLINE Myositis Profile, seven autoantibodies can be determined:antibodies against Mi-2, Ku, PM-Scl, Jo-1, PL-7, PL-12 and Ro-52.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

Order No. FormatsDL 1530-1601 G page 76

Incubated EUROLINE Myositis Profile.

control

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Autoantibodies against Cell Nuclei (ANA)

Microplate ELISA: ANA Screen, Anti-ENA PoolPlus

• Screening test for predifferentiation of antibodies against cell nuclei (ANA) andcytoplasm components.

• Indications: Sharp syndrome (MCTD), systemic lupus erythematosus, Sjögren’ssyndrome, progressive systemic sclerosis, polymyositis/dermatomyositis.

• Serum dilution 1 : 200, conjugate class anti-human IgG, POD-labelled.

• One microplate well incubated per patient.

• 1-point calibration, semiquantitative.

• Native antigens (exception: centromere, recombinant).

• The ANA Screen ELISA supplements the gold standard immunofluorescence. Itis based on a mixture of 10 highly purified antigens, which provide highersensitivity and specificity than the undefined cell extracts used by othermanufacturers.

• Two ELISAs with different antigen combinations, adapted to particular indicationsor for follow-up of immunofluorescence patterns, are available.

Order No. FormatsEA 1590-9601-8 G page 82

Order No. FormatsEA 1590-1208-2 G page 82

Order No. FormatsEA ####-9601 G page 82

Microplate ELISA: SLE Profile 1/2, Anti-ENA ProfilePlus 1/2

• Differentiation of antibodies against cell nuclei (ANA) and cytoplasm com-ponents.

• Indications: Sharp syndrome (MCTD), systemic lupus erythematosus, Sjögren’ssyndrome, progressive systemic sclerosis, polymyositis/dermatomyositis.

• Serum dilution 1 : 200; conjugate class anti-human IgG, POD-labelled.

• 8 or 6 relevant antibodies can be detected simultaneously.

• 1-point calibration, semiquantitive. Calibrator pool and negative controls each ona separate microplate strip (SLE Profiles and Anti-ENA ProfilePlus 2) or on thesame microplate strip as the patient serum.

• Native antigens (exception: Ro-52, centromere and PM-Scl, recombinant).

• In total 4 different ELISAs with different antigen combinations, adapted toparticular indications or for follow-up of immunofluorescence patterns, areavailable.

Microplate ELISA: ANA Single-Antigen ELISAs

• Differentiation of antibodies against cell nuclei (ANA) and cytoplasm com-ponents.

• Indications: rheumatic diseases.

• Serum dilution 1 : 200; conjugate class anti-human IgG, POD-labelled.

• Antibodies against cell nuclei components can be determined quantitatively inRU/ml.

• 3-point calibration, quantitative.

• Identical incubation conditions and times: all single-antigen tests can be com-bined with each other on one microplate.

• Native antigens (exceptions: centromere and PM-Scl, recombinant).

• Single-antigen ELISAs available for detection of antibodies against cell nucleiand cytoplasm antigens: ssDNA, nucleosomes, dsDNA, histones, ribosomal Pproteins, PM-Scl, nRNP/Sm, Sm, SS-A, SS-B, Scl-70, Jo-1, centromere.

• ANA VarioProfile: ELISA test kits (total 12 strips, maximum 4 different microplatestrips) can be individually put together from 14 different antigen-coated micro-plate strips: ssDNA, nucleosomes, dsDNA, histones, ribosomal P-proteins, PM-Scl, nRNP/Sm, Sm, SS-A, SS-B, Scl-70, Jo-1, centromere, AMA M2.

Incubated ELISA ANA Screen (antigen mixture ofdsDNA, histones, nRNP/Sm, Sm, SS-A, SS-B, Scl-70, Jo-1, ribosomal P-proteins, centromere).

Incubated ELISA Anti-ENA ProfilePlus 2 (antigens:ribosomal P-proteins, nRNP/Sm, Sm, SS-A, SS-B,Scl-70, Jo-1, centromere).

Incubated ELISA Anti-SS-A, Anti-SS-B.

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Crithidia luciliae: antibodies against dsDNA.

Incubated ELISA Anti-dsDNA-NcX.

RIA Anti-dsDNA.

Order No. FormatsFA 1572-#### page 131

Order No. FormatsEA 1572-9601 G page 81

Order No. FormatsRA 1571-0001 page 84

Indirect Immunofluorescence Test: Crithidia luciliae

• Detection of antibodies against dsDNA.

• Indication: lupus erythematosus disseminatus.

• Initial dilution: 1:10, conjugate class anti-human IgG, FITC-labelled.

• Animal pathogenic haemoflagellates of Crithidia luciliae are used for the de-tection of autoantibodies against double-stranded, native DNA (dsDNA, nDNA)with indirect immunofluorescence. These protozoa possess a giant mitochon-drion containing dsDNA (kinetoplast) that, in general, does not show any of theother antigens present in the cell nuclei. Antibodies reacting with the kinetoplastare therefore only directed against dsDNA.

• For the detection of antibodies against dsDNA, the sensitivity is much higherwhen using Crithidia luciliae than with HEp-2 cells or tissue sections. This is dueto the different antigen density in the substrate and, when using Crithidia luciliae,the sera is diluted 10 times higher than in the ANA standard test. ELISA or RIAsystems are generally more sensitive than the Crithidia luciliae IFT, but theimmunofluorescence has a higher specificity for SLE. A titer of 1:10 or morecombined with SLE symptoms is indicative of the disease.

Microplate ELISA: Anti-dsDNA-NcX

• Monospecific detection of antibodies against dsDNA.

• Indication: lupus erythematosus disseminatus.

• Serum dilution 1: 200, conjugate class anti-human IgG, POD-labelled.

• Antibodies against dsDNA can be determined quantitatively in IU/ml.

• 3-point calibration, quantitative.

• Antigen: double-stranded DNA, complexed with nucleosomes (NcX).

• Due to good sensitivity and specificity, the Anti-dsDNA-NcX ELISA stands out byhigh diagnostic efficiency. High concentrations of autoantibodies against dsDNAin the ELISA are considered to be a reliable marker for the diagnosis or prognosisof SLE. Individual changes in the dsDNA antibody concentration correlate withthe activity of the disease and can be used for monitoring the development of thedisease in SLE patients. In cases of immunosuppressive therapy or clinicalremission dsDNA antibodies cannot be detected with the ELISA anymore.

Anti-dsDNA RIA by Farr

• Monospecific detection of antibodies against dsDNA.

• ndication: lupus erythematosus disseminatus.

• Use of undiluted samples.

• Antigen: 125I-labelled dsDNA from plasmid DNA.

• The Farr radioimmunoassay has always been of great importance. On the whole,it has the same specificity as the immunofluorescence test and the samesensitivity as the ELISA. Apparently, its well-known high diagnostic efficiency isbased on the fact that only the fraction of the anti-dsDNA antibodies which isable to form bigger precipitating immune complexes with circulating DNA inliquid phase contributes to the measuring signal. The principle of the Farr testreflects, so to speak, the significant step in the pathomechanism of SLE: theformation of appropriate immune complexes, deposits of which build up in thejoints, kidneys, liver and other organs.

Autoantibodies against Double-Stranded DNA (dsDNA)

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Order No. FormatsEA 1505-9601 G page 81

Antibodies against cyclic citrullinated peptides (CCP):An ELISA for specific diagnosis of rheumatoid arthritis

The amino acid citrulline Principle of the anti-CCP ELISA

colourlesschromogen

POD

stain

POD

human antibodyagainst CCP

peroxidase-labelled anti-human antibody

synthetic CCP

Rheumatoid arthritis (RA) is one of themost common autoimmune diseases, affect-ing around 1% of the world population. It ischaracterised by inflammation of the synovialmembrane, which spreads symmetricallyfrom the small to the large joints. Initialsymptoms include painful swelling of fingerjoints with morning stiffness in the joints.Early diagnosis and immediate commence-ment of suitable therapy is necessary to keepthe disease under control.

The most commonly performed serologicaltest in suspected RA cases was until now thedetermination of rheumatoid factors (RF).These are antibodies (predominantly of classIgM) which react with gamma globulins andoccur in 60-80% of RA patients. RF are asensitive but not very specific marker for RA,since they also occur in healthy individualsand in patients with various infections orother autoimmune diseases (systemic lupuserythematosus, Sjögren’s syndrome, sclero-derma and others).

40-60% of RA patients also exhibit autoanti-bodies against epidermal filaggrin1 (RA

keratin, anti-perinuclear factor) in theirserum. Filaggrin is a protein of the epi-dermis, which links keratin filaments to oneanother. Autoantibodies against filaggrin aredetected by indirect immunofluorescence:the antigen substrate rat oesophagus showsstaining of the stratum corneum (RA keratin)on the luminal side; anti-perinuclear factors(APF) are apparent in the cytoplasmicinclusion bodies of human epithelial cells ofthe oral mucosa.

In recent years it has been shown that therare amino acid citrulline, which is presentin filaggrin, is a substantial component of theantigenic epitope. Enzyme immunoassayswhich use synthetic citrullinated peptide asthe target antigen offer a useful alternativeto indirect immunofluorescence2. A directcomparison study demonstrated that thesensitivity can be increased from 49% to 68%by using cyclic citrullinated peptide insteadof linear citrullinated peptide as an ELISAsubstrate3. Antibodies against cyclic citrulli-

nated peptides (CCP) are a new and highlyspecific marker for RA.

Antibodies against CCP are predominantly ofclass IgG and have a specificity of 98% forRA. They are observed very early in thedisease course and have a high predictivevalue: patients with anti-CCP antibodiesdevelop significantly more radiologicallydetectable joint damage than anti-CCP-negative patients4. Antibodies against CCPpossess a much higher specificity than RF(anti-CCP: 97%, RF: 62%) with the same

sensitivity (anti-CCP: 79%, RF: 78%)5. Theycan be detected in early stages of the diseasein 79% of patients.

EUROIMMUN offers an innovative micro-

plate ELISA for quantitative determinationof autoantibodies against CCP. Diluted patientsera are incubated in wells coated withsynthetic cyclic citrullinated peptides (secondgeneration). Specific antibodies in the serumbind to the immobilised antigen and cause aphotometric colour reaction by means of anenzyme-coupled secondary antibody. Five

Anti-CCP ELISA

NH

O NH2

O

N

H

NH

H2N+ NH2

O

N

H

Peptidylarginine-

deiminase (PAD)

Ca2+

L-arginine L-citrulline

calibration sera ensure reliable measure-ment of antibody concentrations. The EURO-IMMUN Anti-CCP ELISA is a highly specificand sensitive serological test system for thediagnosis of RA.

lenaP n evitisopPCC-itnA

ARrofytivitisneS 914 )%5.87(923

citamotpmysAsronoddoolb

004 )%5.0(2

citairosPsitirhtra

82 0

rehtOseditirhtra

53 )%6.8(3

supul.metsySsusotamehtyre

801 )%8.2(3

s'nergöjSemordnys

601 )%9.1(2

amredorelcS 89 )%1.3(3

enummiotuAsitidioryht

951 )%5.2(4

s'renegeWsisotamolunarg

52 )%0.4(1

surivovrap-itnAevitisop-91B

621 )%4.2(3

sedititapehlariV 45 0

evitisopVIH-itnA 5 0

ARrofyticificepS 4411 )%2.89(12

1) Nogueira et al., Ann. Rheum. Dis. 60: 882 (2001)2) Schellekens et al., J. Clin. Invest. 101: 273-281 (1998)3) Schellekens et al., Arthritis Rheum. 43: 155-163 (2000)4) Kroot et al., Arthritis Rheum. 43: 1831-1835 (2000)5) Vasishta, Am. Clin. Lab. 21: 34-36 (2002)

Autoantibodies against Cyclic Citrullinated Peptide (CCP)

Microplate ELISA: Anti-CCP

• Screening test for the specific determination of autoantibodies against cycliccitrullinated peptide (CCP).

• Indication: rheumatoid arthritis (RA).

• Serum dilution 1 : 100; conjugate class anti-human IgG, POD-labelled.

• Antibodies against CCP can be determined quantitatively in RU/ml. Optionalreference control for the determination of ratio values.

• Antigen: synthetic cyclic citrullinated peptides (CCP, second generation).

Incubated ELISA Anti-CCP.

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Autoantibodies against Mitochondria (AMA)

Indirect Immunofluorescence Test: EUROPLUS™ Rat Kidney andM2 BIOCHIPs

• Screening test for the detection of antibodies against mitochondria (AMA) in-cluding simultaneous confirmation of the subtype AMA M2.

• Indication: primary biliary cirrhosis (PBC).

• Initial dilution 1 : 100; polyvalent conjugate anti-human IgAGM, FITC-labelled.

• Rat kidney is the standard substrate for detecting anti-mitochondrial antibodies.Nine AMA types (M1 to M9) can be differentiated.

• The BIOCHIP coated with M2 permits monospecific confirmation of antibodiesagainst the mitochondrial antigen M2 (pyruvate dehydrogenase complex) in onesingle test procedure, thus a PBC can be diagnosed serologically with confidence.

• This BIOCHIP Mosaic™ can be supplemented as required using additionalsubstrates, e.g. HEp-2 cells (ANA, nuclear dots), rat liver (liver-kidney micro-somes, LKM) or rat stomach (ASMA).

Rat kidney and M2 BIOCHIP: antibodies againstmitochondria (AMA).

EUROASSAY: AMA Profile M2, M4, M9

• Differentiation of mitochondrial antibodies (AMA).

• Indication: primary biliary cirrhosis (PBC).

• Serum dilution 1 : 100; conjugate class anti-human IgGM, AP-labelled.

• 3 relevant mitochondrial antibodies can be detected simultaneously and mono-specifically: antibodies against M2, M4, M9.

• Native antigens: pyruvate dehydrogenase complex (M2), sulfite oxidase (M4),glycogen phosphorylase (M9).

Anti- Associated diseases

M2 Primary biliary cirrhosis (high titers), other chronic liver diseases

M4 Primary biliary cirrhosis

M9 Early phase of primary biliary cirrhosis Incubated EUROASSAY AMA Profile M2, M4, M9.

Microplate ELISA: Anti-M2-3E

• Differentiation of mitochondrial antibodies (AMA).

• Indication: primary biliary cirrhosis (PBC).

• Serum dilution 1 : 200; conjugate class anti-human IgG, POD-labelled.

• Antibodies against M2 can be determined quantitatively in RU/ml.

• Antigen: native pyruvate dehydrogenase complex plus recombinant M2 fusionprotein (BPO) containing the immunogenic domains of the E2 subunits of PDH,BCOADH and OGDH.

Incubated ELISA anti-M2-3E.

Order No. FormatsFA 1620-####-3 page 131

Order No. FormatsDA 1620-####-1 O page 75

Order No. FormatsEA 1622-9601 G page 83

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Indirect Immunofluorescence Test: Liver Mosaic 8

• Screening and differentiation test for the detection of liver-specific antibodies,antibodies against mitochondria (AMA), antibodies against cell nuclei (ANA),antibodies against smooth muscles (ASMA), F-actin and other autoantibodies.

• Indications: autoimmune hepatitis, primary biliary cirrhosis, rheumatic diseases.

• Initial dilution 1 : 100; polyvalent conjugate anti-human IgAGM, FITC-labelled.

• The BIOCHIP Mosaic™ consists of 6 substrates: human epithelial cells (HEp-2),primate liver, rat kidney, rat liver, rat stomach, VSM47. Thus, a broad spectrumof antigens is present, allowing not only targeted serological diagnoses, but alsofrequently yielding additional results with clinical relevance.

• Antibodies against cell nuclei (ANA) can be particularly well demonstrated usingHEp-2 cells and primate liver, and are identified according to their fluorescencepatterns. However, they also stain the cell nuclei of the other tissues more or lessintensely. Clinical significance: rheumatic diseases, primary biliary cirrhosis(antibodies against nuclear dots).

• With primate liver, several liver-specific autoantibodies can be investigated e.g.antibodies against liver cell membrane (anti-LMA) and liver-specific protein (anti-LSP). Clinical significance: autoimmune hepatitis.

• Antibodies against mitochondria (AMA) show a granular cytoplasmic fluo-rescence on all 6 substrates. With the standard substrate rat kidney, the proximaland distal tubule cells fluoresce equally. Clinical significance: primary biliarycirrhosis.

• Autoantibodies against liver-kidney microsomes (anti-LKM) react with rat liverand rat kidney (see below). The other substrates are essentially negative.

• In the case of autoantibodies against smooth muscles (ASMA), the tunicamuscularis, the lamina muscularis mucosa as well as the interglandular con-tractile fibrils in the tunica mucosa fluoresce on the rat stomach. ASMA directedagainst the target antigen F-actin furthermore react with the cytoskeleton of HEp-2 cells and the bile canaliculi of primate liver. The substrate VSM47 reacts veryspecifically, showing a filamentous, needle-like fluorescence. Clinical signifi-cance: autoimmune (lupoid) chronic active hepatitis.

• The BIOCHIP Mosaic™ can be supplemented as required with additional sub-strates, e.g. Crithidia luciliae (antibodies against dsDNA), musculus iliopsoas(antibodies against skeletal muscles), heart (antibodies against striated muscles,antibodies against intercalated disks, AMA M7), different EUROPLUS™ sub-strates (AMA M2, Sp100, SLA/LP, LC-1).

HEp-2 cells: anti-nuclear dots. Primate liver: anti-LSP. Rat kidney: AMA. Rat liver: ANA. Ratstomach: ASMA. VSM47: Anti-actin.

Indirect Immunofluorescence Test: BIOCHIP Mosaic™ Rat Liver/RatKidney (Liver Mosaic 1)

• Specific detection of antibodies against liver-kidney microsomes (anti-LKM).

• Indications: autoimmune hepatitis, often associated with extrahepatic syndromessuch as arthralgias, glomerulonephritis, vitiligo and chronic inflammatory boweldiseases.

• Initial dilution 1 : 100; polyvalent conjugate anti-human IgAGM, FITC-labelled.

• Autoantibodies against liver-kidney microsomes react with rat liver and generatea smooth staining in the cytoplasm of the hepatocytes.

• In rat kidney, particularly in the cortex area, a fine granular fluorescence of theproximal tubules – recognizable by the luminal brush border – is visible. Thedistal tubules are negative. The fluorescence intensity of the liver cells isnormally stronger than that of the proximal renal tubules.

• The differentiation between autoimmune hepatitis and virus-induced hepatitiscan additionally be accomplished by investigating the appropriate viralparameters.

Rat liver and rat kidney: antibodies against liver-kidney microsomes (anti-LKM).

Order No. FormatsFA 1300-####-1 page 125

Order No. FormatsFA 1300-####-8 page 125

Autoantibodies against Liver Antigens

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3E (BPO)

Sp100

PML

LKM-1

gp210

LC-1

SLA/LP

Ro-52

EUROLINE: Profile Autoimmune Liver Diseases

• Differentiation of antibodies in autoimmune liver diseases.

• Indications: autoimmune hepatitis, primary biliary cirrhosis, overlap syndromes.

• Serum dilution 1 : 100, conjugate class anti-human IgG, AP-labelled.

• With the EUROLINE Profile Autoimmune Liver Diseases, nine autoantibodies canbe determined: antibodies against AMA M2, M2-3E (BPO), Sp100, PML, gp210,LKM-1, LC-1, SLA/LP and Ro-52.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

• Further antigen combinations on page 77.

Anti- Associated Diseases

M2, Sp100, PML, gp210 Primary biliary cirrhosis

LKM-1, SLA/LP, LC-1 Autoimmune hepatitis

Ro-52 Autoimmune hepatitis, rheumatic diseases

Incubated EUROLINE Profile Autoimmune LiverDiseases.

EUROASSAY: Liver Profile(Anti-M2, -LKM-1, LC-1, -SLA/LP)

• Determination of mitochondrial antibodies AMA M2, antibodies against liver-kidney microsomes type 1 (LKM-1), antibodies against liver cytosolic antigentype 1 (LC-1), as well as of antibodies against soluble liver antigen/liver-pancreasantigen (SLA/LP).

• Indication: autoimmune liver diseases.

• Serum dilution 1 : 100, conjugate class anti-human IgG, AP-labelled.

• Antibodies against M2, LKM-1, LC-1 and SLA/LP can be detected simultaneouslyand monospecifically.

• Antigens: pyruvate dehydrogenase complex (M2, native), cytochrome P450 IID6(LKM-1, recombinant), formiminotransferase-cyclodeaminase (LC-1, recombi-nant) and soluble liver antigen/liver-pancreas antigen (SLA/LP, recombinant). Incubated EUROASSAY M2, LKM-1, LC-1, SLA/LP.

Microplate ELISA: Anti-SLA/LP, Anti-LC-1, Anti-LKM-1

• Monospecific determination of antibodies against soluble liver antigen/liver-pancreas antigen (SLA/LP), cytosolic liver antigen type 1 (LC-1) and liver-kidneymicrosomes type 1 (LKM-1).

• Indication: autoimmune hepatitis.

• Serum dilution 1 : 100, conjugate class anti-human IgG, POD-labelled.

• 3-point calibration, quantitative (exception: Anti-LC-1, semi-quantitative).

• Identical incubation conditions and times: all tests can be combined withoutdifficulty on one and the same microplate.

• Recombinant antigens: soluble liver antigen/liver-pancreas antigen (SLA/LP),formiminotransferase-cyclodeaminase (LC-1) and cytochrome P450 IID6 (LKM-1).The corresponding human cDNA was expressed in E. coli (SLA/LP) or insect cells(LC-1, LKM-1). Incubated ELISA Anti-SLA/LP, Anti-LC-1, Anti-LKM-1.

Order No. FormatsDL 1300-1601-4 G page 76

Order No. FormatsDA 1300-1003-3 G page 75

Order No. (anti-SLA/LP) FormatsEA 1302-9601 G page 81

Autoantibodies against Liver Antigens

AMA M2

control

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Autoantibodies against Thyroid Gland Antigens / Antigen Detections

Indirect Immunofluorescence Test: EUROPLUS™ Thyroid Gland(unfixed) and Thyroglobulin

• Detection of antibodies against thyroid gland antigens.

• Indications: autoimmune thyroid diseases (Basedow’s disease, Hashimoto auto-immune thyroiditis).

• Initial dilution 1 : 10; conjugate class anti-human IgG, FITC-labelled.

• Using unfixed thyroid tissue, two important thyroid-specific antibodies can befound: Autoantibodies against thyroid microsomes (MAb) give a granularstaining in the cytoplasm of the follicle epithelium (target antigen: thyroidperoxidase, TPO). Autoantibodies against thyroglobulin (TAb) react with thecolloid of all follicles of the thyroid tissue and cause a reticular fluorescencepattern.

• With the thyroglobulin-coated BIOCHIP, autoantibodies against thyroglobulin (TG)can be confirmed monospecifically in one and the same test procedure.

• This BIOCHIP Mosaic™ can be supplemented as required with further substrates,e.g. rat kidney, to achieve a differentiation of antibodies against thyroid microso-mes from mitochondrial antibodies (AMA). For a serological diagnosis of auto-immune polyendocrinopathies, BIOC

Thyroid gland, unfixed and thyroglobulinBIOCHIP: antibodies against thyroid microsomesand thyroglobulin.

Radioimmunoassays (RIA/IRMA): Thyroid Specific Autoantibodies,Antigens and Hormones

• Monospecific detection of autoantibodies against thyroglobulin (TG), thyroidperoxidase (TPO) and thyrotropin receptor (TSH-R).

• Specific detection of the thyroid antigen thyrotropin and the hormones freetriiodothyronine (FT3), free thyroxine (FT4), thyrotropin (TSH), calcitonin.

• Indications: autoimmune hyperthyrose s (Graves' disease, Hashimoto'sthyroiditis), medullary thyroid carcinoma, thyroidal C-cell hyperplasia, therapycontrols in hyper- and hypothyrosis.

• Serum dilutions: 1:50 for anti-TG and anti-TPO (magnetic), 1:20 for anti-TG andanti-TPO (precipitation), undiluted for all remaining test kits.

• 5-point to 8-point calibration (quantitative).

Analyte Order No. Analyte Order No.

Anti-TPO RA 1012-####-# FT3 RD 1016-10001

Anti-TG RA 1013-10001-# FT4 RD 1017-10001

TRAb RA 1015-10001 TSH RD 1018-10001

Thyrotropin RD 1013-10001 Calcitonin RD 1019-10001

RIA for thyroid diagnostics.

Microplate ELISA: Anti-Thyroglobulin, Anti-Thyroid Peroxidase,Anti-TSH receptor

• Monospecific determination of antibodies against thyroglobulin (TG), thyroidperoxidase (TPO), and thyrotropin receptor (TSH-R).

• Indications: autoimmune thyroid diseases (Grave’s disease, Hashimoto autoim-mune thyroiditis).

• Serum dilution 1 : 200 (exception: anti-TSH-R undiluted); conjugate class anti-human IgG, POD-labelled (anti-TSH-R: avidin-labelled).

• 3-point calibration (exception: anti-TSH-R, 5-point calibration or semi-quantitative).

• The quantification is carried out according to international reference preparations(anti-TG: NIBSC 65/93; anti-TPO: NIBSC 66/387; anti-TSH-R: NIBSC 90/672).

• Thyroglobulin/TSH-R: native antigen; thyroid peroxidase: recombinant antigen.

Antigen Order No.

Thyroid peroxidase EA 1012-9601 G

Thyroglobulin EA 1013-9601 G

TSH receptor EA 1015-9601 G

Incubated ELISA Anti-Thyroid antigens.

Order No. FormatsFA 1010-####-3 page 120

Order No. (anti-TPO) FormatsRA 1012-####-# page 84

Order No. (Anti-TPO) FormatsEA 1012-9601 G page 81

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CV2/CRMP5

PNMA2 (Ma2/Ta)

Ri

Yo

Hu

Autoantibodies against Neuronal Antigens

Indirect Immunofluorescence Test: BIOCHIP Mosaic™ Cerebellum/Peripheral Nerves/Intestinal Tissue

• Screening test for the detection of antibodies against neuronal antigens.

• Indications: neurological diseases.

• Initial dilution 1 : 10; conjugate class anti-human IgAGM, FITC-labelled.

• Primate cerebellum and primate nerves are the standard substrates for thedetermination of various neuronal antibodies. The parallel use of primateintestine permits the reliable differentiation from other autoantibodies (e.g. ANA)and makes it possible to distinguish between anti-Ri and anti-Hu.

• Antibodies against grey matter react intensively with the stratum granulosumand in a weaker form with the stratum moleculare of the cerebellum. Targetantigen: glutamic acid decarboxylase (GAD). Clinical significance: stiff mansyndrome, diabetes mellitus type I.

• Antibodies against Yo stain exclusively the cytoplasm of the Purkinje cells in thecerebellum. Clinical significance: paraneoplastic cerebellum syndrome, indicationof a malignoma.

• In the case of antibodies against Hu and Ri all neurone nuclei in the grey mattershow a granular fluorescence. Hu antibodies react in the intestine with cell nucleiof the plexus myentericus, whereas Ri antibodies do not. Clinical significance:paraneoplastic cerebellum syndrome, indication of a malignoma.

• Antibodies against neurofilaments appear as a fibrillar structure particularly inthe stratum granulosum. Clinical significance: dysglobulinemias with progressiveaxonal polyneuropathy.

• The white matter of the cerebellum is stained by antibodies against myelin, whichappear as hyaline cylinders on tissue sections of peripheral nerves. Clinicalsignificance: multiple sclerosis (controversial).

• However, antibodies against myelin-associated glycoprotein (MAG) cause arather streaked fluorescence pattern. They can be found in patients with Guillain-Barré syndrome.

• Antibodies against non-medullated nerves react in various organs with segmentsof autonomous nerves. In the intestine, antigens against plexus myentericus andplexus submucosus are targeted. They can be detected in chronic-inflammatorybowel diseases.

• The BIOCHIP Mosaic™ can be supplemented as required with further substrates,e.g. cerebrum (antibodies against astrocytes), primate liver (ANA), Crithidialuciliae (anti-dsDNA), primate stomach (parietal cell antibodies), Borrelia(neuroborreliosis-associated).

Cerebellum: antibodies against GAD and Yo (top),against Hu and Ri (middle). Peripheral nerves:antibodies against myelin and MAG (bottom).

EUROLINE: Neuronal Antigens Profile

• Differentiation of antibodies against neuronal antigens.

• Indication: paraneoplastic neurologic syndromes (PNS).

• Serum dilution 1 : 100; conjugate class anti-human IgG, AP-labelled.

• With the EUROLINE Profile Neuronal Antigens, six autoantibodies can bedetermined: antibodies against amphiphysin, CV2/CRMP5, PNMA2 (Ma2/Ta), Ri,Yo and Hu.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

• Additionally, EUROIMMUN offers a Westernblot for the detection of antibodiesagainst neuronal antigens: DW 1111-1601 G.

Incubated EUROLINE Neuronal Antigens Profile.

Order No. FormatsFA 1111-####-1 page 121

Order No. FormatsDL 1111-1601 G page 76

amphiphysin

control

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Autoantibodies against Islet Cell Antigens

Indirect Immunofluorescence Test: Primate Pancreas

• Detection of antibodies against islet cells.

• Indications: Differentiation between a late manifestation of diabetes type 1 (latentautoimmune diabetes in adulthood, LADA) and diabetes type 2.

• Initial dilution 1 : 10; conjugate class anti-human IgG, FITC-labelled.

• For a reliable determination of antibodies against islet cells an extendedincubation time of 18 hours for the patient serum must be observed. Theincubation time may be reduced to 2 hours but this will lead to a decrease in thesensitivity of the antibody detection test.

• The comparison with a simultaneously tested control serum (order no: CA 1021-0101-1) allows the determination of the antibody concentration in JDF units.

• With indirect immunofluorescence autoantibodies against pancreas islets (ICA)can be detected in 80% of patients with new-onset diabetes type 1. Two targetantigens of ICA have been identified so far: the enzymes glutamic aciddecarboxylase (GAD) and tyrosine phosphatase (IA2).

• This BIOCHIP may be supplemented with further substrates, e. g. primatecerebellum for the detection of antibodies against GAD.

Primate pancreas: antibodies against islet cells.

Microplate ELISA: Anti-GAD, Anti-IA2, Anti-GAD/IA2 Pool

• Monospecific detection of antibodies against glutamic acid decarboxylase (GAD),tyrosine phosphatase (IA2) or bispecific detection of both antibodies in a singlereagent well.

• Indications: early diagnosis of diabetes mellitus type 1, risk prediction in firstgrade relatives, prognosis of the clinical progression of diabetes type 1 forprediction of insulin dependence, differential diagnosis in gestational diabetes,differentiation between a late manifestation of diabetes type 1 (latentautoimmune diabetes in adulthood, LADA) and diabetes type 2.

• Use of undiluted samples. Similar incubation conditions and times. Manual orautomated test performance.

• Multipoint calibration. The quantitation is based on an international referencepreparation (NIBSC 97/550).

• GAD and IA2: human, recombinant antigens.

Antigen Order no.

Glutamic acid decarboxylase (GAD) EA 1022-9601 G

Tyrosinr phosphatase (IA2) EA 1023-9601 G

GAD/IA2 Pool EA 1022-9601-1 G

Incubated ELISA anti-GAD.

RIA: Anti-GAD, Anti-IA2, Anti-Insulin

• Monospecific detection of antibodies against glutamic acid decarboxylase (GAD),tyrosine phosphatase (IA2) and insulin.

• Indications: Early diagnosis of diabetes mellitus type 1, risk prediction in firstgrade relatives, prognosis of the clinical progression of diabetes type 1 forprediction of insulin dependence, differential diagnosis in gestational diabetes,differentiation between a late manifestation of diabetes type 1 (latentautoimmune diabetes in adulthood, LADA) and diabetes type 2.

• Use of undiluted samples. Similar incubation conditions and times. Manual orautomated test performance.

• Test kit formats for 50 or 100 determinations.

• GAD and IA2: human, recombinant, 125I-labelled antigens, insulin: human,synthetic, 125I-labelled antigen.

Antigen Order no.

Glutamat-Decarboxylase (GAD) RA 1022-####

Tyrosin-Phosphatase (IA2) RA 1023-####

Insulin RA 1024-####

RIA Anti-IA2.

Order No. FormatsFA 1020-#### page 120

Order No. (Anti-GAD) FormatsEA 1022-9601 G page 81

Order No. (Anti-IA2) FormatsRA 1023-#### page 84

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sIndirect Immunfluorescence Test: Primate Stomach with UreaPretreatment

• Screening test for detection of antibodies against parietal cells.

• Indications: forms of chronic atrophic gastritis, pernicious anemia, funicularmyelosis, various autoimmune endocrinopathies such as Basedow’s andAddison’s diseases.

• Initial dilution 1 : 10; polyvalent conjugate anti-human IgAGM, FITC-labelled.

• Primate stomach is the standard substrate for detection of parietal cell antibodies.For titration, stomach tissue from rat or mouse is sufficient.

• With positive results the parietal cells show a course granular to clumpyfluorescence, and the surrounding areas are usually dark.

• Parietal cell antibodies (PCA) are often mixed up with antibodies againstmitochondria (AMA) in microscopic analysis. The latter give an even finegranular fluorescence of the parietal cell cytoplasm, with the surrounding regionshowing a (weaker) reaction.

• For reliable differentiation of both types of antibody, a 30-minute pretreatment ofthe tissue sections with urea-glycine buffer (order no. ZF 1140-0101, see page96) is recommended.

• The cytomplasmic fluorescence of parietal cells resulting from PCA occurs withthe same intensity with or without urea pretreatment. The typical pattern ofmitochondrial antibodies is almost completely supressed by urea pretreatment,greatly facilitating PCA diagnostics.

• In some AMA-positive samples it is possible to detect PCA that are obscured bythe AMA pattern in conventional tissue sections.

• The urea-pretreated tissue shows a significantly darker background, enablingspecific fluorescence to be more easily and reliable identified.

• This BIOCHIP can be supplemented with additional substrates, for example,thyroid (thyroid peroxidase, thyroglobulin), pancreas (pancreas islets), adrenalgland (adrenal cortex), ovary (ovary antigens), testis (Leydig cells), and intrinsicfactor.

Primate stomach: antibodies against parietal cells.With urea-pretreatment (top) and without urea-pretreatment (bottom).

Microplate ELISA: Anti-Parietal Cells

• Monospecific detection of antibodies against parietal cells (PCA).

• Indications: forms of chronic atrophic gastritis, pernicious anemia, funicularmyelosis, various autoimmune endocrinopathies such as Basedow’s andAddison’s diseases

• Serum dilution 1 : 200; conjugate class anti-human IgG, POD-labelled.

• 3-point calibration, quantitative.

• Native antigen: H+/K+-ATPase, purified by affinity chromatography.

Incubated ELISA Anti-Parietal Cells.

Order No. FormatsFA 1360-#### G page 126

Order No. FormatsEA 1361-9601 G page 81

Primate stomach: antibodies against mitochon-dria. With urea-pretreatment (top) and withouturea-pretreatment (bottom).

Autoantibodies against Parietal Cells (PCA)

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Autoantibodies against Granulocyte Cytoplasm (cANCA/pANCA)

Indirect Immunofluorescence Test: EUROPLUS™ GranulocyteMosaic 23

• Screening test for the detection of antibodies against granulocyte cytoplasm(ANCA).

• Indications: Wegener’s granulomatosis, various forms of glomerulonephritis,primary sclerosing cholangitis, ulcerative colitis, Crohn’s disease.

• Initial dilution: serum 1 : 10; conjugate class anti-human IgG, FITC-labelled.

• Using ethanol-fixed granulocytes, antibodies against granulocyte cytoplasm canbe detected. In this case, two fluorescence patterns have to be differentiated: agranular fluorescence which is distributed evenly over the entire cytoplasm,leaving the cell nuclei free (cytoplasmic type, cANCA) or a smooth fluorescencewrapped ribbon-like around the cell nuclei (perinuclear type, pANCA).

• Antibodies against all relevant granulocyte antigens as well as against further, asyet unknown antigens are detected simultaneously:

Pattern Target antigen Associated diseases

cANCA Proteinase 3 Wegener’s granulomatosis

pANCA Myeloperoxidase Microscopic arteritis, Churg-Strauss syndrome,polyarteritis nodosa

pANCA Elastase Ulcerative colitis, Crohn’s disease, primary sclero-sing cholangitis, systemic lupus erythematosus

pANCA Cathepsin G Ulcerative colitis, primary sclerosing cholangitis,Crohn’s disease

pANCA Lysozyme Ulcerative colitis, primary sclerosing cholangitis,Crohn’s disease

pANCA Lactoferrin Ulcerative colitis, primary sclerosing cholangitis,Crohn’s disease, systemic lupus erythematosus,rheumatoid arthritis

cANCA BPI Primary sclerosing cholangitis, ulcerative colitis,or pANCA Crohn’s disease

pANCA unknown Ulcerative colitis, Crohn’s disease

• The primate liver enables one to differentiate between pANCA and anti-nuclearantibodies (ANA) which can easily be confused when using ethanol-fixed granu-locytes: In the case of a positive ANA result all nuclei of the hepatocytesfluoresce, whereas in the case of pANCA (as well as cANCA) only thegranulocytes in the sinusoids of primate liver fluoresce.

• The EUROPLUS substrates PR3 and MPO are monospecific tests for the con-firmation of results achieved with conventional granulocyte screening tests. Theyhelp to facilitate the evaluation of problematic fluorescence patterns (e.g.unspecific fluorescence caused by other cytoplasm antibodies).

Microplate ELISA: ANCA Profile

• Differentiation of antibodies against granulocyte cytoplasm (ANCA).

• Indications: Wegener’s granulomatosis, various forms of glomerulonephritis,primary sclerosing cholangitis, ulcerative colitis, Crohn’s disease.

• Serum dilution 1 : 100; conjugate class anti-human IgG, POD-labelled.

• 6 relevant anti-granulocyte antibodies can be detected simultaneously andmonospecifically: autoantibodies against proteinase 3, lactoferrin, myelo-peroxidase, elastase, cathepsin G, BPI.

• 1-point calibration, semi-quantitative. Calibrator pool and serum sample on thesame microplate strip.

• Native antigens, purified by affinity chromatography.

• Available individual ELISA (3-point calibration, quantitative):

Antigen Order No.

Proteinase 3 (classic ELISA) EA 1201-9601 G

Proteinase 3 (Capture ELISA) EA 1201-9601-1 G

Proteinase 3 (PR3-hn-hr: native/recombinant) EA 1201-9601-2 G

Myeloperoxidase EA 1211-9601 G

Incubated ELISA ANCA Profile (antigens: pro-teinase 3, lactoferrin, myeloperoxidase, elastase,cathepsin G, BPI.

Order No. FormatsFA 1201-####-23 page 124

Order No. FormatsEA 1200-1208-1 G page 81

EUROPLUS™ Granulocyte Mosaic 23 (granuloc.(EOH), granuloc. (HCHO), PR3, MPO, HEp-2, pri-mate liver): pattern pANCA, formalin-resistant.

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Screening test indirect immunofluorescence: BIOCHIP quartet granulocytes (EOH),

granulocytes (HCHO), human epithelial cells (HEp-2), and primate liver

AAb againstPR3

(ELISA)

WG 73 %

AAb againstPR3

(capture ELISA)

WG 88 %

AAb againstBPI

WG 5 %

ELISA: anti-PR3 / anti-PR3 capture / ANCA Profile (BPI)

cANCA

Cytoplasmic fluorescenceof granulocytes (A, B, D)

WG 80-90 %MPA 10-15 %CSS 10-20 %PAN < 9 %

pANCA

Perinuclear fluorescence of granulocytes (A, D)

MPA 42-70 %CSS 18-60 %SLE 9-25 %RA 3-25 %

pANCA, formalin-resistant

At B cytoplasmicfluorescence

pANCA, formalin-sensitive

At B no cytoplasmicfluorescence

only ANA

Fluorescence of all cell nuclei(A, C, D)

pANCA, formalin-res. & ANA

Cytoplasmic fluorescenceof granulocytes (B)

pANCA, formalin-sens. & ANA

Nuclei of granuloc. brighter thannuclei of hepatocytes (D), B neg.

pANCA, formalin-sens.? & ANA

ANCA reaction at A,ANA reaction at C & D

Qualified ANA diagnostics: screening test usingHEp-2 cells/primate liver (C, D), differentiation

using ELISA, EUROASSAY, EUROLINE, Westernblot

See EUROIMMUN poster: "Strategy for Determination

of Autoantibodies against Cell Nuclei (ANA)and Cytoplasm Components"

AAb againstMPO

ELISA: anti-MPO

AAb against PR3, MPO,elastase, cathepsin G,

BPI, lactoferrin

WG 5 % (BPI)MPA 53 % (MPO)MPA 3 % (LF)RA, vasculitides 45 % (LF)SLE 6 % (EL)

ELISA: ANCA Profile

ANA and pANCA

Fluorescence of all cell nuclei(A, C, D), granuloc. accent. (D)

MPA 42-70 %

UC 67 %CD 7 %PSC 87 %

MPA 53 %

D

Primateliver

C

HEp-2cells

B

Granulocytes(HCHO-fixed)

A

Granulocytes(EOH-fixed)

AAb against dsDNA, ssDNA, nucleosomes, histones, nuclear membrane, nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Ku, cyclin I (PCNA), mitosin (CENP-F, cyclin II), nuclear dots, centromeres (CENP B), spindle fibres, midbody, centrioles, Scl-70, PM-Scl, fibrillarin, RNA polymerase I, NOR, ribosomal P-proteins, Jo-1, PL-7, PL-12, Mi-2, mitochondria (AMA), lysosomes, Golgi apparatus, vimentin, tropomyosin, actin.

Cost-effective Strategy for the Detection ofAutoantibodies against Granulocyte Cytoplasm (ANCA)

ANA: anti-nuclear antibodies BPI: bactericidal permeability increasing protein cANCA: anti-neutrophil cytoplasmic antibodies, cytoplasmic type CD: Crohn‘s disease CSS: Churg-Strauss syndrome EL: elasta-se EOH: ethanol HCHO: formalin HEp-2: human epithelial cells IFT: immunofluorescence test LF: lactoferrin MPA: microscopic polyangiitis MPO: myeloperoxidase PAN: polyarteritis nodosa pANCA: anti-neutro-phil cytoplasmic antibodies, perinuclear type PR3: proteinase 3 PSC: primary sclerosing cholangitis RA: rheumatoid arthritis SLE: systemic lupus erythematosus UC: ulcerative colitis WG: Wegener‘s granulomatosis

The highest diagnostic sensitivity in the determination of autoantibodies against neutrophil granulocytes (ANCA) is achieved by using indirect immunofluorescence and enzyme immunoassays with defined target antigens (particularly PR3 and MPO) simultaneously at the start. However, under the pressure of cost optimisation, an immunofluorescence test may be performed on its own and then followed up by specific ELISA tests only if the result is positive.

Ethanol-fixed human granulocytes are the standard substrate for indirect immunofluorescence. With this substrate two relevant fluorescence patterns can be differ-entiated: the cytoplasmic type (cANCA) associated with Wegener’s granulomatosis and the perinuclear type (pANCA), which indicates a range of various diseases. The differentiation of pANCA from antibodies against cell nuclei (ANA) is often difficult. Therefore, HEp-2 cells are used as an additional substrate (possibly with sedimented granulocytes). Primate liver is also suitable: the cell nuclei of hepatocytes and granulocytes present in the sinusoids are in the same field of view. If ANA and pANCA occur together, the granulocytes show a much brighter fluorescence than the hepatocyte nuclei.

Thanks to EUROIMMUN BIOCHIPs it is not necessary to incubate human epithelial cells on a second slide in parallel for the exclusion of cell nucleus antibodies, since all substrates are present in one and the same test field. A fourth BIOCHIP with formalin-fixed human granulocytes detects a large proportion of the diagnosti-cally relevant antibodies against myeloperoxidase, whereas other pANCA (which are particularly important in gastroenterology) and almost all antibodies against cell nuclei (whose differentiation is a separate chapter in autoantibody diagnostics) are generally completely suppressed.

With the initial dilution of 1:10 recommended by EUROIMMUN for the indirect immunofluorescence test, some antibodies with a low titre, predominantly against PR3, are not detected. Thus, the prevalence for patients with Wegener’s granulomatosis in IFT is between 80 and 90% (cANCA). With the EUROIMMUN Anti-PR3 Capture ELISA the prevalence can be increased to 92%, detecting Wegener‘s granulomatosis in many individuals in whom the disease had not yet established itself at the time of examination or where it is currently showing a low clinical activity. However, due to the fact that such findings mostly have no therapeutic sig-nificance for these patients, the cost-effective strategy presented in the above scheme is acceptable in general laboratory diagnostics. But when clinical symptoms and laboratory results are contradictory, it is always advisable to use all available methods simultaneously.

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Antibodies against Endomysium and Gliadin

Indirect Immunofluorescence Test: EUROPLUS™ Primate Liver andGliadin BIOCHIPs

• Detection of antibodies against endomysium and gliadin.

• Indications: gluten-sensitive enteropathy (celiac disease, non-tropical sprue),Duhring’s herpetiform dermatitis.

• Initial dilution 1 : 10; conjugate class anti-human IgA, FITC-labelled.

• Autoantibodies against endomysium react with many types of tissue, e.g. primateoesophagus. The most suitable substrate, however, is primate liver: in the caseof a positive sample, filamentous linings of the intralobular sinusoids react.

• With the gliadin-coated BIOCHIP, antibodies against gliadin can be analyzed inone and the same test procedure.

• Both anti-endomysium antibodies and antibodies against gliadin (class IgA) arereliable serological markers for an active gluten-sensitive enteropathy. Therefore,their determination can in many cases replace endoscopy and biopsy.

Primate liver and gliadin BIOCHIP: antibodiesagainst endomysium and gliadin.

Microplate ELISA: Anti-Gliadin (GAF-3X)

• Monospecific detection of antibodies against gliadin.

• Indications: gluten-sensitive enteropathy (celiac disease, non-tropical sprue),Duhring’s herpetiform dermatitis.

• Serum dilution 1 : 200; conjugate class anti-human IgA or IgG, POD-labelled.

• 3-point calibration. Identical incubation conditions and times: the investigation ofIgA and IgG antibodies can be combined without difficulty on one and the samemicroplate.

• Antigen: Gliadin-analogue fusion peptide (GAF-3X).

• The quantitative determination of antibodies against gliadin is very suitable formonitoring the progress of the disease, compliance with a gluten-free diet, or agluten tolerance test.

Incubated ELISA Anti-Gliadin (GAF-3X).

Incubated ELISA Anti-Tissue Transglutaminase(Endomysium).

Microplate ELISA: Anti-Tissue Transglutaminase (Endomysium)

• Monospecific detection of antibodies against tissue transglutaminase.

• Indications: gluten-sensitive enteropathy (celiac disease, non-tropical sprue),Duhring’s herpetiform dermatitis.

• Serum dilution 1 : 200; conjugate class anti-human IgA or IgG, POD-labelled.

• 3-point calibration, quantitative.

• Antigen: recombinant, expression with the baculovirus vector in insect cells.

Order No. FormatsFA 1914-####-1 A page 135

Order No. FormatsEV 3011-9601 A or G page 89

Order No. FormatsEA 1910-9601 A or G page 83

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EUROIMMUN PRODUCTS FOR INFECTIOUS SEROLOGY

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Antibodies against Borrelia/TBE Virus

Indirect Immunofluorescence Test: EUROPLUS™ Anti-Borreliaafzelii, Borrelia burgdorferi, VlsE and OspC Antigen

• Sensitive screening test for the detection of anti-Borrelia antibodies.

• Indications: erythema chronicum migrans, lymphadenosis cutis benigna, lym-phocytic meningoradiculitis, carditis, arthritis, acrodermatitis chronica atro-phicans, neuroborreliosis.

• Initial dilution 1 : 10 (IgM), 1 : 100 (IgG).

• If antibodies against Borrelia afzelii or Borrelia burgdorferi are present, a distinctfluorescence of the bacteria in the smear is obtained.

• With the VlsE or OspC coated BIOCHIPs antibodies against the highly specificand highly sensitive marker antigens VlsE (IgG) or OspC (IgM) can be determinedmonospecifically in one and the same test procedure. If these antigens fluorescethe antibody result is positive even if the bacteria smears show a negativereaction. Thus, the BIOCHIP Mosaic helps to increase specificity and sensitivity inBorrelia diagnostics.

• The BIOCHIP can be supplemented as required using further substrates, e.g.Borrelia burgdorferi sensu stricto (strains CH or USA) and TBE virus infectedcells.

Antibodies against Borrelia afzelii, VlsE (top),Borrelia burgdorferi and OspC (bottom).

Incubated ELISA Anti-Borrelia plus VlsE.

Microplate ELISA: Anti-Borrelia plus VlsE

• Sensitive screening test for the detection of anti-Borrelia antibodies.

• Indications: erythema chronicum migrans, lymphadenosis cutis benigna, lym-phocytic meningoradiculitis, carditis, arthritis, acrodermatitis chronica atro-phicans, neuroborreliosis.

• Serum dilution 1 : 100; conjugate class anti-IgG, anti-IgM or anti-IgAGM (VlsE: -IgGonly), POD-labelled.

• 3-point calibration (IgG and IgM). Identical incubation conditions and times: alltests can be combined without difficulty on one and the same microplate.

• Antigens: extract of Borrelia-burgdorferi sensu stricto, Borrelia garinii andBorrelia afzelii (whole antigen) / recombinant VlsE from Borrelia burgdorferisensu stricto. VlsE (variable major protein-like sequence, expressed) is a newlycharacterized surface protein of Borrelia which is expressed exclusively in vivoand which contains conserved and highly immunogenic epitopes.

• IgM test kit (Anti-Borrelia) includes IgG/RF absorbent in sample buffer for IgGabsorption in preparation for the determination of specific IgM class antibodies.

Microplate ELISA: Anti-TBE Virus

• Sensitive screening test for the detection of anti-TBE virus antibodies.

• Indication: Tick-borne encephalitis (TBE).

• Serum dilution 1 : 100; conjugate class anti-IgG or anti-IgM, POD-labelled.

• 3-point calibration (IgG and IgM). Identical incubation conditions and times: bothtests can be combined without difficulty on one and the same microplate.

• Antigen: native, strain „K23“.

• IgM test kit includes IgG/RF absorbent in sample buffer for IgG absorption inpreparation for the determination of specific IgM class antibodies.

Order No. FormatsFI 2136-####-1 G or M page 139

Order No. FormatsEI 2132-9601 G or M page 85

Order No. FormatsEI 2661-9601 G or M page 87

Incubated ELISA Anti-TBE Virus.

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p 83

p 31, Osp A

p 39, Bmp Ap 41, Flag.

p 34, Osp B

p 18

p 25, Osp Cp 21/22

p 83

p 31, Osp A

p 39, Bmp Ap 41, Flag.

p 25, Osp C

p 30

p 19p 17p 21

VlsE

Automated Evaluation of Incubated Membrane Strips with the System EUROLineScan

• The program EUROLineScan from EUROIM-MUN has been developed to enable quanti-tative evaluation of membrane based testsystems, facilitate management of data, andprovide detailed documentation of results —tasks which have until now required con-siderable time.

• First, the incubated test strips are scannedusing a flatbed scanner or camera system.

• EUROLineScan recognizes the position of thestrips, even if they have been placed inexactly,identifies the bands, and measures their inten-sity. The automated evaluation can be moni-tored, and it is possible to supplement the datamanually.

• The results are then saved together with the image data. It is no longer necessary to archive (potentially infectious) incubated test strips. Aseparate results sheet can be produced for each patient.

Antibodies against Borrelia/TBE Virus

Incubated Westernblot Anti-Borrelia burgdorferi.

Order No. FormatsDY 2132-1601 G or M page 79

Control band

Alignment bar

Westernblot: Anti-Borrelia burgdorferi/B. garinii/B. afzelii

• Specific confirmatory test for the detection of antibodies against the human-pathogen genospecies of Borrelia burgdorferi sensu lato.

• Indications: erythema chronicum migrans, lymphadenosis cutis benigna, lym-phocytic meningoradiculitis, carditis, arthritis, acrodermatitis chronica atro-phicans, neuroborreliosis.

• Serum dilution 1 : 50; conjugate class anti-IgG or anti-IgM, AP-labelled.

• Antigens: SDS extract of a Borrelia burgdorferi strain.

• Bands from all specific antigens are included and clearly separated.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

Incubated EUROLINE-WB Anti-Borrelia.

Order No. FormatsDY 2131-1601-1 G or M page 79

Control band

EUROLINE-WB: Anti-Borrelia (Whole Antigen plus VlsE)

• Specific confirmatory test for the detection of antibodies against Borrelia.

• Indications: erythema chronicum migrans, lymphadenosis cutis benigna, lym-phocytic meningoradiculitis, carditis, arthritis, acrodermatitis chronica atro-phicans, neuroborreliosis.

• Serum dilution 1 : 50; conjugate class anti-IgG or anti-IgM, AP-labelled.

• Antigens: SDS extract of a Borrelia afzelii strain.

• EUROLINE-WB is a combination of westernblot and line blot techniques. An SDSextract of a Borrelia afzelii strain is electrophoretically separated according tomolecular mass and transferred onto a nitrocellulose membrane. A membranechip coated with highly purified recombinant VlsE-Antigen is then added to thewesternblot strips.

• By additionally determining antibodies against VlsE the serological hit rate canbe increased by 20% compared to whole extract Westernblots and by 30%compared to recombinant antigen Westernblots. Of all recombinant antigens,VlsE possesses the highest sensitivity for the detection of a Borrelia infection.Over 85% of IgG-positive sera could be identified at a glance by assessing theVlsE band. VlsE allows detection of antibodies against all Borrelia species, andthe risk of a false negative reaction due to species differences is ten times lower.

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Antibodies against Epstein-Barr Virus (EBV)

Indirect Immunofluorescence Test: BIOCHIP Sequence EBV

• Gold standard for the detection of antibodies against the antigens EBV-CA(Epstein-Barr virus capsid antigen), EBV-EA (Epstein-Barr early antigen) andEBNA (Epstein-Barr nuclear antigen).

• Indications: infectious mononucleosis, Burkitt’s lymphoma, nasopharyngealcarcinoma.

• For each patient (format 1001) 1 slide is incubated according to the following scheme:

• Class IgG antibodies against EBV-CA indicate an EBV infection. An at least two-fold increase in titer and the absence of antibodies against EBNA at the sametime characterize the early stage of an infection. Class IgM antibodies againstEBV-CA as well as antibodies against EBV-EA may also occur in a primaryinfection, but are not obligatory. If antibodies against EBNA are present, the latephase of an EBV infection has usually been reached.

• If a primary EBV infection cannot be differentiated with confidence from a relapseor reinfection, the determination of the antibody avidity using a modifiedimmunofluorescence test as an additional parameter can be beneficial (seeincubation scheme). Therefore, a further incubation with urea solution (ZF 1130-0801) must be carried out. The detection of low-avidity antibodies against EBV-CA proves a primary infection.

• IgG absorbtion in preparation for the determination of IgM antibodies: page 56.

• Further anti-EBV test kits for indirect immunofluorescence:

Substrate Order No. Substrate Order No.

EBV-CA FI 2791-#### G EBV-EA FI 2795-#### G

EBV-CA FI 2791-#### M EBV-CA & EBV-EA FI 2791-####-2 G

EBNA FI 2793-#### G (2 BIOCHIPs per field)

Antibodies against Epstein-Barr virus: anti-EBV-CA (top), anti-EBNA (middle), anti-EBV-EA(bottom).

Microplate ELISA: Anti-EBV-CA, Anti-EBNA-1, Anti-EBV-EA

• Specific confirmatory test for antibodies against EBV-CA, EBNA-1 or EBV-EA.

• Indications: infectious mononucleosis, Burkitt’s lymphoma, nasopharyngealcarcinoma.

• Serum dilution 1 : 100; conjugate class anti-IgA, -IgG or IgM, POD-labelled.

• 1-point calibration, semi-quantitative (IgA, IgM) or 3-point calibration, quantita-tive (IgG). Identical incubation conditions and times: all tests can be combinedwithout difficulty on one and the same microplate.

• EBV-CA: native antigen, purified by affinity chromatography; EBNA-1 and EBV-EA:recombinant antigen.

• IgM test kit includes IgG/RF absorbent in sample buffer for IgG absorption inpreparation for the determination of specific IgM class antibodies.

• Available individual ELISA:

Antigen Order No.

EBV-CA EI 2791-9601 A, G or M

EBNA-1 EI 2793-9601 G

EBV-EA EI 2795-9601 A, G or M

Incubated ELISA Anti-EBNA-1.

Order No. FormatsFI 2799-####-1 X page 152

Order No. (anti-EBNA-1) FormatsEI 2793-9601 G page 89

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-itna-CTIFGgInamuh

-itna-CTIFMgInamuh

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-itna-CTIFc3Cnamuh

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0

2

4

6

8

10

0 25 50 75 100

VCA gp125VCA p19EBNA-1

p22EA-D

VCA 125

VCA 65

VCA 40/41/42

VCA 33

VCA 22

EA REBNA-1

EA D

Antibodies against Epstein-Barr Virus (EBV)

EUROLINE: EBV Profile 2

• Differentiation of antibodies against Epstein-Barr virus antigens.

• Indications: infectious mononucleosis, Burkitt’s lymphoma, nasopharyngealcarcinoma.

• Serum dilution 1 : 100; conjugate class anti-human IgG or IgM, AP-labelled.

• With the EUROLINE EBV Profile 2, five different antibodies can be determined:antibodies against VCA gp125, VCA p19, EBNA-1, p22, EA-D.

• Recombinant antigens (exception: VCA gp125, native, purified by affinity chro-matography).

• EBNA-1 (IgG) negative und VCA (IgG and IgM) positive: acute (fresh) infection.

• EBNA-1 (IgG) and VCA (IgG) positive and VCA (IgM) negative: late phase of infection.

• EBNA-1 (IgG) negative, but band p22 (IgG) and VCA (IgG) positive: late phase ofinfection with loss of anti-EBNA-1.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

Westernblot: Anti-EBV

• Specific confirmatory test for the detection of antibodies against Epstein-Barrvirus antigens, differentiation of antibodies against Epstein-Barr virus antigens.

• Indications: infectious mononucleosis, Burkitt’s lymphoma, nasopharyngealcarcinoma.

• Serum dilution 1 : 50; conjugate class anti-IgG or anti-IgM, AP-labelled.

• Antigens: whole antigen, SDS extract.

• Bands from all specific antigens are included and clearly separated.

• EBNA-1 (IgG) negative und VCA (IgG and IgM) positive: acute (fresh) infection.

• EBNA-1 (IgG) and VCA (IgG) positive and VCA (IgM) negative: late phase of infection.

• EBNA-1 (IgG) negative, but band p22 (IgG) and VCA (IgG) positive: late phase ofinfection with loss of anti-EBNA-1.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

Incubated Westernblot Anti-EBV.

Order No. FormatsEI 2791-9601-1 G page 88

Order No. FormatsDN 2790-1601-2 G or M page 77

Order No. FormatsDY 2790-1501 G or M page 80

Control band

Avidity of antibodies against EBV-CA (IgG)

Relative Avidity Index (RAI) in %

Nu

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RAI =Ewith urea

Ewithout urea

Primary Infection

Previous Infection

Determination of Low-Avidity Antibodies against EBV-CA

• An alternative principle for the serological diagnosis of fresh infections with EBVhas been established by investigating the antibody avidity.

• The first reaction of the immune system following an infection is the formation oflow-avidity antibodies. As the infection proceeds, increasingly antigen-adaptedIgG is formed, and avidity grows. As long as high-avidity IgG is not yet detectedin the serum, it can be assumed that the infection is still in an early stage.

• To identify low-avidity antibodies against EBV-CA in a patient’s serum, two micro-plate ELISA or immunofluorescence tests are performed in parallel: one test iscarried out in the conventional way, the other one includes urea treatmentbetween incubations with patient’s serum and peroxidase-labelled anti-humanIgG, resulting in the detachment of low-avidity antibodies from the antigens.

• Low-avidity antibodies against EBV-CA are present if the ELISA extinction issignificantly reduced by urea treatment. For an objective interpretation, therelative avidity index (RAI) can be calculated out of the measured values with andwithout urea incubation.

• With the immunofluorescence test the presence of low-avidity antibodies hasbeen proved if the test using urea treatment gives a far weaker fluorescence thanthe two-step test.

Control

Incubated EUROLINE EBV Profile 2.

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p 120, CagA

p 33

p 95, VacA

p 30p 29, UreAp 26

p 19, OMPp 17

p 66, UreB

Antibodies against Helicobacter pylori

Indirect Immunofluorescence Test: Anti-Helicobacter pylori

• Sensitive screening test for the detection of antibodies against Helicobacterpylori.

• Indications: gastritis, ulcus ventriculi et duodeni. Late consequences: MALTlymphomas and adenocarcinomas.

• Initial dilution 1 : 10 (IgM), 1 : 100 (IgG), 1 : 32 (IgA).

• If antibodies against Helicobacter pylori are present, a distinct fluorescence of thebacteria in the smear is obtained.

• A positive IgA result correlates well with the activity of a gastritis. An increasedIgG antibody titer is considered to be a marker for chronic infections. A signifi-cant drop in the IgG antibody titer about 6 months after therapy is a sign ofsuccess.

• The BIOCHIP can be supplemented as required with further substrates, e.g. otherinfectious agents or tissue sections of primate stomach.

Antibodies against Helicobacter pylori.

Microplate ELISA: Anti-Helicobacter pylori

• Sensitive screening test for the detection of antibodies against Helicobacterpylori.

• Indications: gastritis, ulcus ventriculi et duodeni. Late consequences: MALTlymphomas and adenocarcinomas.

• Serum dilution 1 : 100; conjugate class anti-IgA or anti-IgG, POD-labelled.

• Antibodies against Helicobacter pylori antigens can be determined quantitativelyin RU/ml.

• 1-point calibration, semi-quantitative (IgA) or 3-point calibration, quantitative(IgG). Identical incubation conditions and times: both tests can be combinedwithout difficulty on one and the same microplate.

• Native antigens.Incubated ELISA Anti-Helicobacter pylori.

Westernblot: Anti-Helicobacter Pylori

• Specific confirmatory test for the detection of antibodies against Helicobacterpylori.

• Indications: gastritis, ulcus ventriculi et duodeni. Late consequences: MALTlymphomas and adenocarcinomas.

• Serum dilution 1 : 50; conjugate class anti-IgA or anti-IgG, AP-labelled.

• Antigens: antigen extract from a particularly suitable Helicobacter pylori strain.

• Bands from all specific antigens are included and clearly separated.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

Incubated Westernblot Anti-Helicobacter pylori.

Order No. FormatsFI 2080-#### A or G page 137

Order No. FormatsEI 2080-9601 A or G page 85

Order No. FormatsDY 2080-1601 A or G page 79

Control band

Alignment bar

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gB 1

gD 1

gC 1

gG 2

Antibodies against Herpes Simplex Virus (HSV)

Indirect Immunofluorescence Test: BIOCHIP Mosaic™ HSV-1/HSV-2

• Sensitive screening test for the detection of antibodies against herpes simplexviruses.

• Indication: herpes simplex.

• Initial dilution 1 : 10 (IgM), 1 : 100 (IgG).

• If antibodies against herpes simplex-2 virus are present in the sample, a typicalfluorescence of the infected cells is obtained – mainly in the outspread cyto-plasm, less in the cell nuclei.

• As HSV-1 and HSV-2 are morphologically and immunologically closely related,cross-reactions can occur. Differentiation may be attempted by testing a serumagainst both antigen substrates and comparing the titers.

• The BIOCHIP Mosaic™ can be supplemented as required with further substrates,e.g. other infectious agents.

• Anti-HSV individual tests for indirect immunofluorescence:

Substrate Order No.

HSV-1 FI 2531-#### G or M

HSV-2 FI 2532-#### G or M

HSV-1 and -2 FI 2531-####-1 G or M

Antibodies against HSV-1 and HSV-2.

Microplate ELISA: Anti-HSV-1, Anti-HSV-2

• Specific confirmatory tests for antibodies against HSV-1 or HSV-2.

• Indication: herpes simplex.

• Serum dilution 1 : 100; conjugate class anti-IgG or anti-IgM, POD-labelled.

• 1-point calibration, semiquantitative (IgM) or 3-point calibration, quantitative(IgG). Identical incubation conditions and times: all tests can be combinedwithout difficulty on one and the same microplate.

• Antigens: type-specific glycoproteins C1 or G2, purified by affinity chromato-graphy. Cross-reactions do not occur.

• IgM test kit includes IgG/RF absorbent in sample buffer for IgG absorption inpreparation for the determination of specific IgM class antibodies.

• Available individual ELISA:

Antigen Order No.

HSV-1 EI 2531-9601-2 G or M

HSV-2 EI 2532-9601-2 G or M

HSV-1/2-Pool EI 2531-9601-1 G or M

Incubated ELISA Anti-HSV-1.

EUROLINE-WB: Anti-HSV

• Specific confirmatory test for the differentiation of antibodies against HSV-1 andHSV-2.

• Indication: herpes simplex.

• Serum dilution 1 : 50; conjugate class anti-IgG or anti-IgM, AP-labelled.

• EUROLINE-WB is a combination of westernblot and line blot techniques. Proteinsfrom an SDS extract of HSV-1 are electrophoretically separated according tomolecular mass and transferred onto a nitrocellulose membrane. A membranechip coated with HSV-2 type-specific glycoprotein G2 (gG 2), purified by affinitychromatography, is then added to the westernblot strips.

• Bands from all specific antigens are included and clearly separated.

• The gG 2 band allows the simple differentiation between HSV-1 and HSV-2infections.

• Test strips can be automatically incubated and evaluated using the systemsEUROBlotMaster und EUROLineScan (see page 28).

Incubated EUROLINE-WB Anti-HSV.

Order No. FormatsFI 2531-####-1 G or M page 145

Order No. (anti-HSV-1) FormatsEI 2531-9601-2 G or M page 86

Order No. FormatsDY 2531-1601-1 G or M page 80

Alignment bar

Control band

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FI 2821-1001-1 G FI 2822-1001-1 G

RESPIRATORY TRACT PROFILE 1 EXANTHEMA PROFILE 1IgG IgM IgG IgM

Field A 1 : 10 1 : 10 Field A 1 : 10 1 : 10

1. RSV 1. HHV-62. Adenovirus type 3 2. Rubella virus*3. Influenza virus type A (H1N1) 3. Measles virus4. Influenza virus type A (H3N2) 4. Mumps virus

Field B 1 : 10 1 : 10 Field B 1 : 10 1 : 10

5. Influenza virus type B 5. VZV6. Parainfluenza virus type 1 6. EBV-CA**7. Parainfluenza virus type 2 7. EBV-EA8. Parainfluenza virus type 3 8. Treponema pallidum

Field C 1 : 10 1 : 10 Field C 1 : 100 1 : 10

9. Parainfluenza virus type 4 9. HSV-110. Bordetella pertussis** 10. HSV-211. Bordetella parapertussis** 11. Coxsackie virus type B112. Mycoplasma pneumoniae 12. Coxsackie virus type A9

Field D 1 : 100 1 : 10 Field D 1 : 100 1 : 10

13. Coxsackie virus type B1 13. Echo virus type 714. Coxsackie virus type A7 14. Borrelia afzelii15. Echo virus type 7 15. Borrelia burgdorferi sensu stricto (CH)16. Chlamydia pneumoniae 16. Borrelia garinii

Field E 1 : 100 1 : 100 Field E 1 : 100 1 : 100

17. Haemophilus influenzae*,** 17. CMV18. Klebsiella pneumoniae* 18. Candida albicans**19. Legionella pneumophila serotype 1*,** 19. Candida krusei*,**20. Legionella pneumophila serotype 12*,** 20. Candida tropicalis*,**

FI 2823-1001-1 G FI 2824-1001-1 G

LYMPHADENITIS PROFILE 1 CENTRAL NERVOUS SYSTEM PROFILE 1IgG IgM IgG IgM

Field A 1 : 10 1 : 10 Field A 1 : 10 1 : 10

1. HIV-1* 1. Rubella virus*2. HIV-2* 2. Measles virus3. HHV-6 3. Mumps virus4. Rubella virus* 4. VZV

Field B 1 : 10 1 : 10 Field B 1 : 10 1 : 10

5. Measles virus 5. Adenovirus type 36. Mumps virus 6. EBV-CA**7. Adenovirus type 3 7. Treponema pallidum8. Parainfluenza virus type 1 8. Toxoplasma gondii**

Field C 1 : 10 1 : 10 Field C 1 : 100 1 : 10

9. EBV-CA** 9. HSV-110. EBV-EA 10. HSV-211. Toxoplasma gondii** 11. Coxsackie virus type B112. Treponema pallidum 12. Coxsackie virus type A7

Field D 1 : 100 1 : 10 Field D 1 : 100 1 : 10

13. HSV-1 13. Echo virus type 714. HSV-2 14. Borrelia afzelii15. CMV** 15. Borrelia burgdorferi sensu stricto (CH)16. Coxsackie virus type B5 16. Borrelia garinii

Field E 1 : 100 1 : 10 Field E 1 : 100 1 : 100

17. Coxsackie virus type A9 17. CMV18. Bartonella henselae** 18. Haemophilus influenzae*,**19. Chlamydia trachomatis** 19. Listeria monocytogenes 1/2a*20. Chlamydia pneumoniae 20. Listeria monocytogenes 4b*

BIOCHIP Mosaics™ for Infectious Serology(For formats see pages 152-153)

* For clinical evaluation the results must be confirmed with a CE approved test.

** For practical reasons the recommended incubation differs from the standard incubation for this substrate.

BIOCHIP Mosaics™ containing fewer substrates can be produced upon request.

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* For clinical evaluation the results must be confirmed with a CE approved test.

** For practical reasons the recommended incubation differs from the standard incubation for this substrate.

BIOCHIP Mosaics™ containing fewer substrates can be produced upon request.

BIOCHIP Mosaics™ for Infectious Serology(For formats see pages 152-153)

FI 2825-1001-1 G FI 2826-1001-1 G

MYOCARDITIS PROFILE 1 INFECTARTHRITIS PROFILE 1IgG IgM IgG IgM

Field A 1 : 10 1 : 10 Field A 1 : 10 1 : 10

1. Mumps virus 1. VZV2. Adenovirus type 3 2. Influenza virus type A (H1N1)3. Influenza virus type A (H1N1) 3. Influenza virus type A (H3N2)4. Influenza virus type A (H3N2) 4. Influenza virus type B

Field B 1 : 10 1 : 10 Field B 1 : 10 1 : 10

5. Influenza virus type B 5. Yersinia enterocolitica O:3*,**6. Parainfluenza virus type 1 6. Yersinia enterocolitica O:6*,**7. Parainfluenza virus type 2 7. Yersinia enterocolitica O:9*,**8. Mycoplasma pneumoniae 8. Toxoplasma gondii**

Field C 1 : 100 1 : 10 Field C 1 : 100 1 : 10

9. CMV** 9. Borrelia afzelii10. Coxsackie virus type B1 10. Borrelia burgdorferi sensu stricto (CH)11. Coxsackie virus type A16 11. Borrelia garinii12. Echo virus type 7 12. Chlamydia trachomatis**

Field D 1 : 100 1 : 10

13. Borrelia afzelii14. Borrelia burgdorferi sensu stricto (CH)15. Borrelia garinii16. Chlamydia pneumoniae

FI 2827-1001-1 G FI 2828-1001-1 G

GASTROINTESTINAL TRACT PROFILE 1 ACCOMPANYING HEPATITIS PROFILE 1IgG IgM IgG IgM

Field A 1 : 10 1 : 10 Field A 1 : 10 1 : 10

1. Adenovirus type 3 1. Adenovirus type 32. Yersinia enterocolitica O:3*,** 2. EBV-CA**3. Yersinia enterocolitica O:6*,** 3. EBV-EA4. Yersinia enterocolitica O:9*,** 4. Toxoplasma gondii**

Field B 1 : 100 1 : 10 Field B 1 : 100 1 : 10

5. Coxsackie virus type B3 5. HSV-16. Coxsackie virus type A7 6. HSV-27. Echo virus type 7 7. CMV**8. Campylobacter jejuni*,** 8. Coxsackie virus type B5

Field C 1 : 100 1 : 100 Field C 1 : 10 1 : 10

9. Campylobacter coli*,** 9. Coxsackie virus type A910. Helicobacter pylori** 10. Echo virus Typ 711. Klebsiella pneumoniae* 11. Echinococcus granulosus**12. Candida albicans**

FI 2829-1001-1 G FI 2831-1001-1 G

OPHTHALMOLOGY PROFILE 1 PREGNANCY PROFILE 1IgG IgM IgG IgM

Field A 1 : 10 1 : 10 Field A 1 : 10 1 : 10

1. Measeles virus 1. Rubella virus*2. VZV 2. Toxoplasma gondii**3. Adenovirus type 3 3. HIV-1*4. Toxoplasma gondii** 4. HIV-2*

Field B 1 : 100 1 : 10 Field B 1 : 100 1 : 10

5. HSV-1 5. Chlamydia trachomatis**6. HSV-2 6. CMV**7. Coxsackie virus type A24 7. HSV-28. Chlamydia trachomatis** 8. VZV**

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IgG Absorption in Preparation for the Determination

of Specific IgM Class Antibodies

Principle

• Before a patient’s serum is tested for specific antibodies of the IgM class, anti-bodies of class IgG must be removed by ultracentrifugation, chromatography orimmunoabsorption.

• Specifically bound IgG would displace IgM from the antigen leading to false IgMnegative test results.

• Moreover, the absorption prevents any IgM class rheumatoid factors presentfrom reacting with specifically bound IgG and thus leading to false IgM positivetest results.

• Indication: an IgG absorption of serum samples should always be performed forall IgM antibody determinations in infectious serology before incubating the sera.

EUROSORB IgG/RF Absorbent for Indirect Immunofluorescence

• Functional principle: the EUROSORB reagent contains an anti-human IgG anti-body preparation from goat. Immunoglobulin G of a serum or plasma sample isbound with high specificity by these antibodies and precipitated. If the samplealso contains rheumatoid factors, these will be absorbed by the anti-human IgG/IgG complex.

• Incubation time of the sample with the reagent is 15 minutes. A centrifugationstep for a subsequent investigation by immunofluorescence is recommended.

• All IgG subclasses are bound and precipitated by the anti-human IgG antibodies.

• Human serum IgG in concentrations of up to 15 mg/ml and rheumatoid factorsare completely removed by the absorbent (average serum IgG concentration inadults: 12 mg/ml).

• The recovery rate of the IgM fraction is almost 100%.

• One unit contains 4.5 ml absorbent, sufficient for the absorption of 100 serumsamples.

EUROSORB IgG/RF Absorbent.

rheumatoid factor

IgG

absorbent

Order No. FormatsZF 1270-0145 page 157

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EUROIMMUN PRODUCTS FOR ALLERGOLOGY

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EUROLINE: Specific IgE

• Determination of specific IgE in serum.

• Indication: Clarification of allergic reactions to inhalation allergens, food allergensand cross-reactive allergens (pollen-associated food allergies).

• Serum dilution: undiluted (or 1 : 10); conjugate class anti-IgE (monoclonal), AP-labelled.

• Calibration: 3 indicator bands on each strip for semiquantitative evaluation.

• Antibodies against up to 20 allergens per strip can be simultaneously mono-specifically detected.

• EUROLINE profiles with different allergen compositions are available for varioustest requirements: atopy, inhalation, food and cross reactions.

• The program EUROLineScan from EUROIMMUN has been developed to enablequantitative evaluation of EUROLINE analyses, facilitate management of data,and provide detailed documentation of results.

• The incubated EUROLINE test strips are scanned using a flatbed scanner.EUROLineScan recognizes the position of the strips, even if they have beenplaced inexactly, identifies the bands, and measures their intensity.

Incubated EUROLINE Allergy Profile Inhalation.

EUROIMMUN Microplate ELISA: Total IgE

• Determination of the total IgE concentration in serum.

• Indications: Differentiation between allergic and intrinsic asthma, betweenallergic and vasomotor rhinitis, and between atopic and seborrhoic dermatitis.

• Serum dilution 1 : 10; conjugate class anti-IgE (monoclonal), POD-labelled.

• One microplate well incubated per patient.

• 4-point calibration, quantitative.

• Coating: anti-human IgE, polyclonal.

• The Total IgE ELISA serves as a screening test for allergy diagnostics andprovides an indication for the presence of an allergic reaction.

Incubated ELISA Total IgE.

EUROASSAY: Specific IgE

• Determination of specific IgE in serum.

• Indication: Clarification of allergic reactions to inhalation allergens, foodallergens, insect venoms and latex and latex-related allergens.

• Serum dilution: undiluted; conjugate class anti-IgE (monoclonal), AP-labelled.

• Antibodies against up to 7 allergens per field and 35 allergens per slide can besimultaneously monospecifically detected.

• EUROASSAY profiles with different allergen compositions are available forvarious test requirements: inhalation, food, domestic animals, insect venoms,latex, latex plus.

Incubated EUROASSAY Allergy Profile Inhalation.

grasses

animal hair

trees

mould spores

weeds

indicators

mites

Antibodies of Class IgE against Allergens

Order No. (Inhalation) Formate and PriceDE 3110-#### E Page 76

Order No. (Inhalation) Format and PriceDP 3110-1601 E Page 77

Order No. Format and PriceEV 3840-9601 E Page 89

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

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Antibodies of Class IgE against Allergens

Order No. Format and PriceEP ####-0110 E Page 90-119

AllercoatTM 6 ELISA.

Allercoat™ 6 Microplate ELISA: specific IgE

• Determination of allergen-specific IgE concentrations in serum.

• Indication: identification of allergic reactions to more than 600 different allergensand allergen mixtures.

• Serum dilution: undiluted, conjugate class anti-human IgE, AP-labelled.

• One microplate well per allergen/allergen mixture is incubated for each patient.

• Calibration: 6-point calibration, quantitative; using reference preparation 2 IRP 75/502 from the WHO.

• The allergens are coupled to paper rings and can be flexibly configured for eachsample according to the analysis.

• Customized pre-assembled microplates with individual allergy parameters areavailable on request (Order no.: EP 9901-0101). Orders can be made online withthe provided software. Please contact us!

• A light table and special evaluation software are available to supplement thesimple manual Allercoat™ 6 ELISA procedure.

• Allercoat™ 6 ELISA are automatable.

Fitting of allergen rings intomicroplate wells

Incubate: 60 min, 37 °C

Wash: 300 µl wash bufferper well

allergen rings

undilutedsamples

enzymeconjugate

chromogen-/substrate sol.

Pipette: 50 µl per well

Pipette: 50 µl per well

Incubate: 60 min, 37 °C

Evaluate: photometric measurementat a wavelength of 405 nm

Wash: 300 µl wash bufferper well

Pipette: 100 µl per well

Incubate: 30 min, 37 °C

Pipette: 100 µl per well

stopsolution

Individual equipmentwith allergen rings

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

ORDER INFORMATION AND PRODUCT DATA

Product Classification— AF: Fluorescence-labelled antibodies for EUROIMMUN IIFT— CA: Control for EUROIMMUN IIFT (autoimmunity)— CI: Control for EUROIMMUN IIFT (infectious serology)— CV: Control for EUROIMMUN IIFT (determination of further antibodies)— CW: Control for EUROIMMUN Westernblot/EUROLINE-WB— DA: EUROASSAY test system (autoimmunity)— DE: EUROASSAY test system (allergology)— DL: EUROLINE test system (autoimmunity)— DN: EUROLINE test system (infectious serology)— DP: EUROLINE test system (allergology)— DW: Westernblot/EUROLINE-WB test system (autoimmunity)— DY: Westernblot/EUROLINE-WB test system (infectious serology)— EA: Microplate ELISA test system (autoimmunity)— EI: Microplate ELISA test system (infectious serology)— EP: Microplate ELISA test system (allergology)— EQ: Microplate ELISA test system (serum proteins and tumour markers)— EV: Microplate ELISA test system (determination of further antibodies)— FA: Test system for indirect immunofluorescence (autoimmunity)— FB: Single slides for indirect immunofluorescence (autoimmunity)— FI: Test system for indirect immunofluorescence (infectious serology)— FK: Single slides for indirect immunofluorescence (infectious serology)— FV: Test system for indirect immunofluorescence (determination of further antibodies)— FX: Single slides for indirect immunofluorescence (determination of further antibodies)— RA: Radioimmunoassay (autoimmunity)— RD: Radioimmunoassay (direct detection of autoantigens, hormone determination)— ZF: Further reagents for EUROIMMUN IIFT— ZZ: Other items for EUROIMMUN IIFT

Product Code

Format— 1601: 16 single test strips— 1208: 12 microplate strips with 8 wells each— 9601: 96 individual break-apart wells (12 microplate strips with 8 wells each)— 5001: 50 individual tubes— 0001: 100 individual tubes— 1003: 10 slides with 3 fields each— 1005: 10 slides with 5 fields each— 2005: 20 slides with 5 fields each— 1010: 10 slides with 10 fields each— 1050: 10 slides with 50 fields each— 1096: 10 slides with 96 fields each— 1001: 10 slides to be incubated with 1 patient serum each— 1002: 10 slides to be incubated with 2 patient sera each

FI 2531 - 1005 -1 G Immunoglobulin Class— A: IgA— E: IgE— G: IgG— M: IgM— O: IgGM— P: Polyvalent (IgAGM)— X: low-avide antibodies of class IgG— H: high-avide antibodies of class IgG

When placing an order, please indicate quantity, order number and designation of the required product. Examples:

2 x FA 1300-1010 liver, monkey (2 test systems with 10 slides each, 10 fields per slide)

1 x FA 1620-2005-1 kidney, rat / stomach, rat (1 test system with 20 slides, 5 fields per slide)

2 x FI 2610-1003 G Measles virus (2 IgG class test systems with 10 slides each, 3 fields per slide)

Test systems comprise all reagents needed to perform the serological investigation, for diagnostics in indirect immunofluorescence, e.g.slides, FITC-labelled antibodies against human immunoglobulin, positive and negative control sera (not available for some products) as wellas embedding medium, cover glasses, sachets of PBS and Tween 20. EUROSORB for the determination of IgM class antibodies is notincluded in the immunofluorescence test systems. Single slides are supplied with cover glasses only.

Substrates consisting of cell cultures and tissues which do not appear in this catalogue can be made to specification. In addition, BIOCHIPMosaics™ can be produced according to individual requirements. Apart from the customary package sizes and slide formats, special sizesare available as well. Quotations can be provided upon request.

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Price (€)Antiserum FormatOrder No.

Fluorescence-Labelled Antibodies: Fluorescein (FITC) for EUROIMMUN IIFT

AF 101-0115 FITC-labelled anti-human IgA 1.5 ml (ready for use) 15.50AF 101-0160 (goat) 6.0 ml (ready for use) 50.00

AF 102-0115 FITC-labelled anti-human IgG 1.5 ml (ready for use) 15.50AF 102-0160 (goat) 6.0 ml (ready for use) 50.00

AF 103-0115 FITC-labelled anti-human IgM 1.5 ml (ready for use) 15.50AF 103-0160 (goat) 6.0 ml (ready for use) 50.00

AF 106-0115 FITC-labelled anti-human IgAGM 1.5 ml (ready for use) 15.50AF 106-0160 (IgA + IgG + IgM goat) 6.0 ml (ready for use) 50.00

AF 107-0115 FITC-labelled anti-human IgAG 1.5 ml (ready for use) 15.50AF 107-0160 (IgA + IgG goat) 6.0 ml (ready for use) 50.00

AF 112-0115 FITC-labelled anti-human C3c 1.5 ml (ready for use) 15.50AF 112-0160 (goat) 6.0 ml (ready for use) 50.00

AF 302-0115 FITC-labelled anti-human IgG 1.5 ml (ready for use) 31.00AF 302-0160 (goat) 6.0 ml (ready for use) 70.00

primate absorbed

AF 601-0115 FITC-labelled anti-human IgA 1.5 ml (ready for use) 15.50AF 601-0160 (goat) 6.0 ml (ready for use) 50.00

with Evans Blue

AF 602-0115 FITC-labelled anti-human IgG 1.5 ml (ready for use) 15.50AF 602-0160 (goat) 6.0 ml (ready for use) 50.00

with Evans Blue

AF 603-0115 FITC-labelled anti-human IgM 1.5 ml (ready for use) 15.50AF 603-0160 (goat) 6.0 ml (ready for use) 50.00

with Evans Blue

AF 606-0115 FITC-labelled anti-human IgAGM 1.5 ml (ready for use) 15.50AF 606-0160 (IgA + IgG + IgM goat) 6.0 ml (ready for use) 50.00

with Evans Blue

AF 607-0115 FITC-labelled anti-human IgAG 1.5 ml (ready for use) 15.50AF 607-0160 (IgA + IgG goat) 6.0 ml (ready for use) 50.00

with Evans Blue

AF 612-0115 FITC-labelled anti-human C3c 1.5 ml (ready for use) 15.50AF 612-0160 (goat) 6.0 ml (ready for use) 50.00

with Evans Blue

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*) Currently not available as IVD in the European Union.

Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Organ-Specific Autoantibodies

Ig Class

CA 1000-0101 autoantibody-free control IgG 0.1 ml 5.00(aab negative)

CA 1010-0101 antibodies against thyroid microsomes IgG 0.1 ml 5.00and thyroglobulin (MAb+TAb control)

CA 1011-0101 antibodies against thyroid microsomes IgG 0.1 ml 5.00(MAb control)

CA 1013-0101 antibodies against thyroglobulin IgG 0.1 ml 5.00(TAb control)

CA 1021-0101 antibodies against pancreas islets IgG 0.1 ml 5.00(islet cell ab control)

CA 1021-0101-1 antibodies against pancreas islets IgG 0.1 ml 5.00control with indication of titer in JDF units

CA 1022-0101 antibodies against glutamic acid decarboxylase IgG 0.1 ml 5.00(GAD ab control)

CA 1051-0101 antibodies against adrenal cortex IgG 0.1 ml 5.00(adrenal cortex ab control)

CA 1061-0101 antibodies against ovary: theca cells IgG 0.1 ml 5.00(ovary ab control)

CA 1063-0101 antibodies against ovary: zona pellucida IgG 0.1 ml 5.00(zona pellucida ab control)

CA 1071-0101 * antibodies against placenta: IgG 0.1 ml 5.00syncytiotrophoblast (placenta ab control)

CA 1081-0101 antibodies against testis: Leydig cells IgG 0.1 ml 5.00(testis ab control)

CA 1086-0101 antibodies against spermatozoa IgG 0.1 ml 5.00(spermatozoa ab control)

CA 1111-0101 antibodies against brain: grey matter IgG 0.1 ml 5.00(stiff man syndrome; SMS control)

CA 1113-0101 antibodies against Purkinje cell cytoplasm IgG 0.1 ml 5.00(Yo ab control)

CA 1115-0101 antibodies against neurone nuclei: Ri antigen IgG 0.1 ml 5.00(Ri ab control)

CA 1116-0101 antibodies against neurone nuclei: Hu antigen IgG 0.1 ml 5.00(Hu ab control)

CA 1121-0101 antibodies against myelin IgG 0.1 ml 5.00(myelin ab control)

CA 1123-0101 antibodies against myelin-associated IgG 0.1 ml 5.00glycoprotein (MAG ab control)

CA 1125-0101 antibodies against medullated nerves IgG 0.1 ml 5.00(myelin sheath ab control)

CA 1126-0101 antibodies against neuroendothelium IgG 0.1 ml 5.00(neuroendothelium ab control)

CA 1127-0101 antibodies against neurofilaments IgG 0.1 ml 5.00(neurofilament ab control)

CA 1129-0101 antibodies against non-medullated nerves IgG 0.1 ml 5.00(non-medullated nerves ab control)

CA 1200-0101 antibodies against granulocyte cytoplasm, IgG 0.1 ml 5.00cytoplasmic pattern (cANCA control, Wegener’s granulomatosis)

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Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Organ-Specific Autoantibodies

Ig Class

CA 1200-1060-1 antibodies against granulocyte cytoplasm, IgG 10 x 60 µl, ready for use 50.00CA 1200-8060-1 aliquots from positive control for ANCA diagnostics 80 x 60 µl, ready for use 350.00

(10 different fluorescence patterns)

CA 1210-0101 antibodies against granulocyte cytoplasm, IgG 0.1 ml 5.00perinuclear pattern (pANCA control)

CA 1211-0101 antibodies against myeloperoxidase IgG 0.1 ml 5.00(MPO ab control)

CA 1218-0101 antibodies against granulocyte cytoplasm, IgG 0.1 ml 5.00perinuclear pattern (xANCA control)

CA 1230-0101 antibodies against thrombocytes IgG 0.1 ml 5.00(thrombocyte ab control)

CA 1251-0101 antibodies against renal glomeruli IgG 0.1 ml 5.00(Goodpasture syndrome; GBM ab control)

CA 1252-0101 antibodies against renal tubuli IgG 0.1 ml 5.00(TBM ab control)

CA 1301-0101 antibodies against liver-specific protein IgG 0.1 ml 5.00(LSP ab control)

CA 1304-0101 antibodies against liver membrane IgG 0.1 ml 5.00(LMA control)

CA 1306-0101 antibodies against bile canaliculi IgG 0.1 ml 5.00(bile canaliculi ab control)

CA 1320-0101 antibodies against liver-kidney microsomes IgG 0.1 ml 5.00(LKM ab control)

CA 1361-0101 antibodies against parietal cells IgG 0.1 ml 5.00(PCA control)

CA 1362-0101 antibodies against intrinsic factor IgG 0.1 ml 5.00(intrinsic factor ab control)

CA 1363-0101 antibodies against parietal cells + intrinsic factor IgG 0.1 ml 5.00(PCA + intrinsic factor ab control)

CA 1381-0101 A antibodies against intestinal goblet cells IgA 0.1 ml 5.00(ulcerative colitis; UC IgA control)

CA 1381-0101 G antibodies against intestinal goblet cells IgG 0.1 ml 5.00(ulcerative colitis; UC IgG control)

CA 1391-0101 antibodies against pancreas acini IgG 0.1 ml 5.00(Crohn’s disease 1 control)

CA 1392-0101 antibodies against pancreas secretion IgG 0.1 ml 5.00(Crohn’s disease 2 control)

CA 1421-0101 antibodies against parotid excretory ducts IgG 0.1 ml 5.00(parotid gland ab control)

CA 1431-0101 antibodies against striated muscles IgG 0.1 ml 5.00(myasthenia gravis control)

CA 1461-0101 antibodies against striation IgG 0.1 ml 5.00(heart 1 ab control)

CA 1462-0101 antibodies against intercalated discs IgG 0.1 ml 5.00(heart 2 ab control)

CA 1501-0101 antibodies against epidermis: desmosomes IgG 0.1 ml 5.00(pemphigus vulgaris control)

CA 1502-0101 antibodies against epidermis: basement membrane IgG 0.1 ml 5.00(bullous pemphigoid control)

CA 1508-0101 antibodies against keratin IgG 0.1 ml 5.00(filaggrin ab control)

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CA 1570-0101 antibodies against cell nuclei IgG 0.1 ml 5.00(ANA control), homogeneous pattern

CA 1570-0850-1 antibodies against cell nuclei (ANA control), IgG 8 aliquots concentrate 50 µl each 20.00CA 1570-9650-1 homogeneous pattern 96 aliquots concentrate 50 µl each200.00

control serum with indication of titer

CA 1570-2060-2 antibodies against cell nuclei, IgG 20 x 60 µl, ready for use 100.00CA 1570-8060-2 aliquots from positive control for ANA diagnostics 80 x 60 µl, ready for use 350.00

(20 different fluorescence patterns)

CA 1572-0101 antibodies against dsDNA IgG 0.1 ml 5.00(dsDNA ab control)

CA 1580-0101 antibodies against cell nuclei IgG 0.1 ml 5.00(ANA control), nucleolar pattern

CA 1581-0101 antibodies against RNA IgG 0.1 ml 5.00(RNA ab control)

CA 1590-0101 antibodies against cell nuclei IgG 0.1 ml 5.00(ANA control), granular pattern

CA 1591-0101 antibodies against U1-nRNP IgG 0.1 ml 5.00

CA 1593-0101 antibodies against Sm IgG 0.1 ml 5.00

CA 1595-0101 antibodies against SS-A (Ro) IgG 0.1 ml 5.00

CA 1597-0101 antibodies against SS-B (La) IgG 0.1 ml 5.00

CA 1599-0101 antibodies against Scl-70 IgG 0.1 ml 5.00

CA 1601-0101 antibodies against PCNA (cyclin I) IgG 0.1 ml 5.00

CA 1602-0101 antibodies against mitosin (cyclin II) IgG 0.1 ml 5.00

CA 1603-0101 antibodies against Sp100 (nuclear granula, IgG 0.1 ml 5.00nuclear dots; PBC-associated)

CA 1605-0101 antibodies against Ku IgG 0.1 ml 5.00(Ku ab control)

CA 1608-0101 antibodies against nuclear membrane IgG 0.1 ml 5.00(lamin ab control)

CA 1611-0101 antibodies against cell nuclei IgG 0.1 ml 5.00(ANA control), centromere pattern

CA 1613-0101 antibodies against spindle fibers (MSA-1) IgG 0.1 ml 5.00

CA 1620-0101 antibodies against mitochondria IgG 0.1 ml 5.00(AMA control)

CA 1622-0101 antibodies against mitochondria IgG 0.1 ml 5.00(AMA M2 control; PBC-associated)

CA 1629-0101 antibodies against mitochondria IgG 0.1 ml 5.00(AMA M9 control)

CA 1641-0101 antibodies against ribosomes IgG 0.1 ml 5.00

CA 1642-0101 antibodies against Golgi apparatus IgG 0.1 ml 5.00

CA 1651-0101 antibodies against F-actin IgG 0.1 ml 5.00(F-actin control)

CA 1652-0101 antibodies against vimentin IgG 0.1 ml 5.00

CA 1661-0101 antibodies against histidyl-tRNA synthetase IgG 0.1 ml 5.00(Jo-1 ab control)

CA 1710-0101 antibodies against smooth muscles IgG 0.1 ml 5.00(ASMA control)

CA 1711-0101 antibodies against actin IgG 0.1 ml 5.00

Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Systemic Autoantibodies

Ig Class

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Further control sera for the determination of autoantibodies available upon request.

Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Systemic Autoantibodies

Ig Class

CA 1910-0101 A antibodies against endomysium IgA 0.1 ml 5.00(endomysium IgA control)

CA 1913-0101 A antibodies against endomysium plus gliadin IgA 0.1 ml 5.00(endomysium plus gliadin IgA control)

CA 1950-0101 G antibodies against elastin IgG 0.1 ml 5.00(elastin ab control)

CA 1960-0101 G antibodies against vascular endothelium IgG 0.1 ml 5.00(vascular endothelium ab control)

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*) Currently not available as IVD in the European Union.

Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Infectious Serology

Ig Class

CI 2050-0101 A antibodies against Bordetella pertussis IgA 0.1 ml 5.00IgA positive control

CI 2050-0101 G antibodies against Bordetella pertussis IgG 0.1 ml 5.00IgG positive control

CI 2050-0101 M antibodies against Bordetella pertussis IgM 0.1 ml 5.00IgM positive control

CI 2050-0101 Z Bordetella pertussis/parapertussis IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2055-0101 A antibodies against Bordetella parapertussis IgA 0.1 ml 5.00IgA positive control

CI 2055-0101 G antibodies against Bordetella parapertussis IgG 0.1 ml 5.00IgG positive control

CI 2055-0101 M antibodies against Bordetella parapertussis IgM 0.1 ml 5.00IgM positive control

CI 2070-0101 G * antibodies against Haemophilus influenzae IgG 0.1 ml 5.00IgG positive control

CI 2070-0101 Z * Haemophilus influenzae IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2080-0101 A antibodies against Helicobacter pylori IgA 0.1 ml 5.00IgA positive control

CI 2080-0101 G antibodies against Helicobacter pylori IgG 0.1 ml 5.00IgG positive control

CI 2080-0101 M antibodies against Helicobacter pylori IgM 0.1 ml 5.00IgM positive control

CI 2080-0101 Z Helicobacter pylori IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2091-0101 G * antibodies against Campylobacter jejuni IgG 0.1 ml 5.00IgG positive control

CI 2091-0101 Z * Campylobacter jejuni/coli IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2092-0101 G * antibodies against Campylobacter coli IgG 0.1 ml 5.00IgG positive control

CI 2101-0101 G * antibodies against Klebsiella pneumoniae IgG 0.1 ml 5.00IgG positive control

CI 2101-0101 Z * Klebsiella pneumoniae IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2111-0101 G antibodies against Treponema pallidum IgG 0.1 ml 5.00FTA IgG positive control

CI 2111-0101 M antibodies against Treponema pallidum IgM 0.1 ml 5.00FTA IgM positive control

CI 2111-0101 Z Treponema pallidum IgA, IgG, IgM 0.1 ml 5.00FTA negative control

CI 2111-0150-1 G antibodies against Treponema pallidum IgG 50 µl serum concentrate 5.00IgG positive control for FTA absorption

CI 2121-0101 G antibodies against Reiter spirochetes IgG 0.1 ml 5.00unspecific FTA IgG positive control

CI 2131-0101 G antibodies against Borrelia afzelii/B. burgdorferi/B. garinii IgG 0.1 ml 5.00IgG positive control

CI 2131-0101 M antibodies against Borrelia afzelii/B. burgdorferi/B. garinii IgM 0.1 ml 5.00IgM positive control

CI 2131-0101 Z Borrelia afzelii/B. burgdorferi/B. garinii IgA, IgG, IgM 0.1 ml 5.00negative control

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*) Currently not available as IVD in the European Union.

Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Infectious Serology

Ig Class

CI 213a-0101 M antibodies against Borrelia (OspC antigen) IgM 0.1 ml 5.00IgM positive control

CI 213b-0101 G antibodies against Borrelia (VlsE antigen) IgG 0.1 ml 5.00IgG positive control

CI 2140-0101 Z * Listeria monocytogenes IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2141-0101 G * antibodies against Listeria monocytogenes 1/2a IgG 0.1 ml 5.00IgG positive control

CI 2144-0101 G * antibodies against Listeria monocytogenes 4b IgG 0.1 ml 5.00IgG positive control

CI 2150-0101 P antibodies against Legionella pneumophila serotypes 1 or 4 IgAGM 0.1 ml 5.00positive control

CI 2151-0101 G * antibodies against Legionella pneumophila serotype 1 IgG 0.1 ml 5.00IgG positive control

CI 2151-0101 Z Legionella pneumophila/non-pneumophila IgA, IgG, IgM 0.1 ml 5.00negative control

CI 215b-0101 P antibodies against Legionella pneumophila mixture 1-4-6-8 IgAGM 0.1 ml 5.00IgAGM positive control

CI 215d-0101 P antibodies against Legionella pneumophila mixture 2-3-5-7 IgAGM 0.1 ml 5.00IgAGM positive control

CI 215f-0101 P antibodies against Legionella pneumophila mixture 9-11-13 IgAGM 0.1 ml 5.00IgAGM positive control

CI 215h-0101 P antibodies against Legionella pneumophila mixture 10-12-14 IgAGM 0.1 ml 5.00IgAGM positive control

CI 2173-0101 G * antibodies against Yersinia enterocolitica IgG 0.1 ml 5.00IgG positive control

(for diagnosing variousforms of arthritis)

CI 2173-0101 Z * Yersinia enterocolitica IgA, IgG, IgM 0.1 ml 5.00negative control

(for diagnosing variousforms of arthritis)

CI 2191-0101 A antibodies against Chlamydia trachomatis IgA 0.1 ml 5.00IgA positive control

CI 2191-0101 G antibodies against Chlamydia trachomatis IgG 0.1 ml 5.00IgG positive control

CI 2191-0101 M antibodies against Chlamydia trachomatis IgM 0.1 ml 5.00IgM positive control

CI 2191-0101-1 Z Chlamydia IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2192-0101 A antibodies against Chlamydia pneumoniae IgA 0.1 ml 5.00IgA positive control

CI 2192-0101 G antibodies against Chlamydia pneumoniae IgG 0.1 ml 5.00IgG positive control

CI 2192-0101 M antibodies against Chlamydia pneumoniae IgM 0.1 ml 5.00IgM positive control

CI 219a-0101 G * antibodies against Afipia felis IgG 0.1 ml 5.00IgG positive control

CI 219a-0101 Z * Afipia felis IgA, IgG, IgM 0.1 ml 5.00negative control

CI 219b-0101 G antibodies against Bartonella henselae IgG 0.1 ml 5.00IgG positive control

CI 219b-0101 M antibodies against Bartonella henselae IgM 0.1 ml 5.00IgM positive control

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Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Infectious Serology

Ig Class

CI 219b-0101 Z Bartonella henselae/quintana IgA, IgG, IgM 0.1 ml 5.00negative control

CI 219d-0101 G antibodies against Bartonella quintana IgG 0.1 ml 5.00IgG positive control

CI 219d-0101 M antibodies against Bartonella quintana IgM 0.1 ml 5.00IgM positive control

CI 2201-0101 G antibodies against Mycoplasma hominis IgG 0.1 ml 5.00IgG positive control

CI 2201-0101 Z Mycoplasma hominis/pneumoniae and IgA, IgG, IgM 0.1 ml 5.00Ureaplasma urealyticum negative control

CI 2202-0101 G antibodies against Mycoplasma pneumoniae IgG 0.1 ml 5.00IgG positive control

CI 2202-0101 M antibodies against Mycoplasma pneumoniae IgM 0.1 ml 5.00IgM positive control

CI 2205-0101 G antibodies against Ureaplasma urealyticum IgG 0.1 ml 5.00IgG positive control

CI 2231-0101 A antibodies against Leishmania donovani IgA 0.1 ml 5.00IgA positive control

CI 2231-0101 G antibodies against Leishmania donovani IgG 0.1 ml 5.00IgG positive control

CI 2231-0101 M antibodies against Leishmania donovani IgM 0.1 ml 5.00IgM positive control

CI 2231-0101 Z Leishmania donovani IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2260-0101-1 G antibodies against Plasmodia IgG 0.1 ml 5.00IgG positive control

CI 2260-0101-1 Z Plasmodia IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2320-0101 A antibodies against Echinococcus granulosus IgA 0.1 ml 5.00IgA positive control

CI 2320-0101 G antibodies against Echinococcus granulosus IgG 0.1 ml 5.00IgG positive control

CI 2320-0101 Z Echinococcus granulosus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2410-0101 A * antibodies against Toxoplasma gondii IgA 0.1 ml 5.00IgA positive control

CI 2410-0101 G antibodies against Toxoplasma gondii IgG 0.1 ml 5.00IgG positive control

CI 2410-0101 H high-avid antibodies against Toxoplasma gondii IgG 0.1 ml 5.00IgG positive control

CI 2410-0101 M antibodies against Toxoplasma gondii IgM 0.1 ml 5.00IgM positive control

CI 2410-0101 X low-avid antibodies against Toxoplasma gondii IgG 0.1 ml 5.00IgG positive control

CI 2410-0101 Z Toxoplasma gondii IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2511-0101 G * antibodies against HIV-1 IgG 0.1 ml 5.00IgG positive control

CI 2511-0101 Z * HIV-1/2 IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2512-0101 G * antibodies against HIV-2 IgG 0.1 ml 5.00IgG positive control

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Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Infectious Serology

Ig Class

CI 2531-0101 G antibodies against Herpes simplex virus 1 (HSV-1) IgG 0.1 ml 5.00IgG positive control

CI 2531-0101 M antibodies against Herpes simplex virus 1 (HSV-1) IgM 0.1 ml 5.00IgM positive control

CI 2531-0101 Z HSV-1/HSV-2 IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2532-0101 G antibodies against Herpes simplex virus 2 (HSV-2) IgG 0.1 ml 5.00IgG positive control

CI 2532-0101 M antibodies against Herpes simplex virus 2 (HSV-2) IgM 0.1 ml 5.00IgM positive control

CI 2536-0101 G antibodies against human herpes virus 6 (HHV-6) IgG 0.1 ml 5.00IgG positive control

CI 2536-0101 Z human herpes virus 6 (HHV-6) IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2570-0101 A antibodies against Cytomegalovirus (CMV) IgA 0.1 ml 5.00IgA positive control

CI 2570-0101 G antibodies against Cytomegalovirus (CMV) IgG 0.1 ml 5.00IgG positive control

CI 2570-0101 M antibodies against Cytomegalovirus (CMV) IgM 0.1 ml 5.00IgM positive control

CI 2570-0101 Z Cytomegalovirus (CMV) IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2590-0101 G antibodies against Rubella virus IgG 0.1 ml 5.00IgG positive control

CI 2590-0101 H high-avid antibodies against Rubella virus IgG 0.1 ml 5.00IgG positive control

CI 2590-0101 X low-avid antibodies against Rubella virus IgG 0.1 ml 5.00IgG positive control

CI 2590-0101 Z Rubella virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2601-0101 A antibodies against SARS coronavirus IgA 0.1 ml 5.00IgA positive control

CI 2601-0101 G antibodies against SARS coronavirus IgG 0.1 ml 5.00IgG positive control

CI 2601-0101 M antibodies against SARS coronavirus IgM 0.1 ml 5.00IgM positive control

CI 2601-0101 Z SARS coronavirus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2610-0101 G antibodies against Measles virus IgG 0.1 ml 5.00IgG positive control

CI 2610-0101 M antibodies against Measles virus IgM 0.1 ml 5.00IgM positive control

CI 2610-0101 Z Measles virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2630-0101 G antibodies against Mumps virus IgG 0.1 ml 5.00IgG positive control

CI 2630-0101 M antibodies against Mumps virus IgM 0.1 ml 5.00IgM positive control

CI 2630-0101 Z Mumps virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2650-0101 A antibodies against Varicella zoster virus (VZV) IgA 0.1 ml 5.00IgA positive control

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*) Currently not available as IVD in the European Union.

Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Infectious Serology

Ig Class

CI 2650-0101 G antibodies against Varicella zoster virus (VZV) IgG 0.1 ml 5.00IgG positive control

CI 2650-0101 M antibodies against Varicella zoster virus (VZV) IgM 0.1 ml 5.00IgM positive control

CI 2650-0101 Z Varicella zoster virus (VZV) IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2661-0101 A antibodies against TBE virus IgA 0.1 ml 5.00IgA positive control

CI 2661-0101 G antibodies against TBE virus IgG 0.1 ml 5.00IgG positive control

CI 2661-0101 M antibodies against TBE virus IgM 0.1 ml 5.00IgM positive control

CI 2661-0101 Z TBE virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2662-0101 G antibodies against West-Nile virus IgG 0.1 ml 5.00IgG positive control

CI 2662-0101 H high-avid antibodies against West-Nile virus IgG 0.1 ml 5.00IgG positive control

CI 2662-0101 M antibodies against West-Nile virus IgM 0.1 ml 5.00IgM positive control

CI 2662-0101 X low-avid antibodies against West-Nile virus IgG 0.1 ml 5.00IgG positive control

CI 2662-0101 Z West-Nile virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2663-0101 G * antibodies against Japanese encephalitis virus IgG 0.1 ml 5.00IgG positive control

CI 2663-0101 M * antibodies against Japanese encephalitis virus IgM 0.1 ml 5.00IgM positive control

CI 2663-0101 Z * antibodies against Japanese encephalitis virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2665-0101 G antibodies against Yellow fever virus IgG 0.1 ml 5.00IgG positive control

CI 2665-0101 M antibodies against Yellow fever virus IgM 0.1 ml 5.00IgM positive control

CI 2665-0101 Z Yellow fever virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 266a-0101 G antibodies against Dengue virus IgG 0.1 ml 5.00IgG positive control

CI 266a-0101 M antibodies against Dengue virus IgM 0.1 ml 5.00IgM positive control

CI 266a-0101 Z Dengue virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2670-0101 A antibodies against Respiratory syncytial virus (RSV) IgA 0.1 ml 5.00IgA positive control

CI 2670-0101 G antibodies against Respiratory syncytial virus (RSV) IgG 0.1 ml 5.00IgG positive control

CI 2670-0101 M antibodies against Respiratory syncytial virus (RSV) IgM 0.1 ml 5.00IgM positive control

CI 2670-0101 Z Respiratory syncytial virus (RSV) IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2680-0101 A antibodies against Adenovirus IgA 0.1 ml 5.00IgA positive control

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*) Currently not available as IVD in the European Union.

CI 2680-0101 G antibodies against Adenovirus IgG 0.1 ml 5.00IgG positive control

CI 2680-0101 M antibodies against Adenovirus IgM 0.1 ml 5.00IgM positive control

CI 2680-0101 Z Adenovirus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2691-0101 A antibodies against Influenza virus type A IgA 0.1 ml 5.00IgA positive control

CI 2691-0101 G antibodies against Influenza virus type A IgG 0.1 ml 5.00IgG positive control

CI 2691-0101 M antibodies against Influenza virus type A IgM 0.1 ml 5.00IgM positive control

CI 2691-0101 Z Influenza virus type A/B IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2692-0101 A antibodies against Influenza virus type B IgA 0.1 ml 5.00IgA positive control

CI 2692-0101 G antibodies against Influenza virus type B IgG 0.1 ml 5.00IgG positive control

CI 2692-0101 M antibodies against Influenza virus type B IgM 0.1 ml 5.00IgM positive control

CI 2720-0101 A antibodies against Parainfluenza virus types 1 - 4 IgA 0.1 ml 5.00IgA positive control

CI 2720-0101 G antibodies against Parainfluenza virus types 1 - 4 IgG 0.1 ml 5.00IgG positive control

CI 2720-0101 M antibodies against Parainfluenza virus types 1 - 4 IgM 0.1 ml 5.00IgM positive control

CI 2720-0101 Z Parainfluenza virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2730-0101 G antibodies against Coxsackie virus IgG 0.1 ml 5.00IgG positive control

CI 2730-0101 Z Coxsackie virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 275a-0101 G antibodies against Echo virus IgG 0.1 ml 5.00IgG positive control

CI 275a-0101 Z Echo virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 277a-0101-1 G * antibodies against Sandfly fever virus IgG 0.1 ml 5.00IgG positive control

CI 277a-0101-1 Z * Sandfly fever virus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 278h-0101-1 G antibodies against Hantavirus IgG 0.1 ml 5.00IgG positive control

CI 278h-0101-1 M antibodies against Hantavirus IgM 0.1 ml 5.00IgM positive control

CI 278h-0101-1 Z Hantavirus IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2791-0101 A antibodies against Epstein-Barr virus capsid antigen (EBV-CA) IgA 0.1 ml 5.00IgA positive control

CI 2791-0101 G antibodies against Epstein-Barr virus capsid antigen (EBV-CA) IgG 0.1 ml 5.00IgG positive control

CI 2791-0101 H high-avid antibodies against Epstein-Barr virus capsid antigen (EBV-CA) IgG 0.1 ml 5.00IgG positive control

Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Infectious Serology

Ig Class

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Price (€)Control(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Determination of Further Antibodies

Ig Class

CV 2841-0101 A antibodies against Saccharomyces cerevisiae IgA 0.1 ml 5.00IgA positive control

CV 2841-0101 G antibodies against Saccharomyces cerevisiae IgG 0.1 ml 5.00IgG positive control

CV 2841-0101 M antibodies against Saccharomyces cerevisiae IgM 0.1 ml 5.00IgM positive control

CV 2841-0101 Z Saccharomyces cerevisiae IgA, IgG, IgM 0.1 ml 5.00negative control

CV 3011-0101 A antibodies against gliadin IgA 0.1 ml 5.00(gliadin IgA control)

CV 3011-0101 G antibodies against gliadin IgG 0.1 ml 5.00(gliadin IgG control)

Price (€)Control

(Ready for Use)

FormatOrder No.

Controls for EUROIMMUN IIFT: Infectious Serology

Ig Class

CI 2791-0101 M antibodies against Epstein-Barr virus capsid antigen (EBV-CA) IgM 0.1 ml 5.00IgM positive control

CI 2791-0101 X low-avid antibodies against Epstein-Barr virus (EBV-CA) IgG 0.1 ml 5.00IgG positive control

CI 2791-0101 Z Epstein-Barr virus (EBV) IgA, IgG, IgM 0.1 ml 5.00negative control

CI 2793-0101 C antibodies against Epstein-Barr virus nuclear antigen (EBNA) IgG 0.1 ml 5.00complement-binding, positive control

CI 2795-0101 A antibodies against Epstein-Barr virus early antigen (EBV-EA) IgA 0.1 ml 5.00IgA positive control

CI 2795-0101 G antibodies against Epstein-Barr virus early antigen (EBV-EA) IgG 0.1 ml 5.00IgG positive control

CI 2795-0101 H high-avid antibodies against Epstein-Barr virus early antigen (EBV-EA) IgG 0.1 ml 5.00IgG positive control

CI 2795-0101 X low-avid antibodies against Epstein-Barr virus early antigen (EBV-EA) IgG 0.1 ml 5.00IgG positive control

CI 2861-0101 A antibodies against Candida albicans IgA 0.1 ml 5.00IgA positive control

CI 2861-0101 G antibodies against Candida albicans IgG 0.1 ml 5.00IgG positive control

CI 2861-0101 M antibodies against Candida albicans IgM 0.1 ml 5.00IgM positive control

CI 2861-0101 Z Candida albicans IgA, IgG, IgM 0.1 ml 5.00negative control

CI 293a-0101 G antibodies against Chikungunya virus IgG 0.1 ml 5.00IgG positive control

CI 293a-0101 M antibodies against Chikungunya virus IgM 0.1 ml 5.00IgM positive control

CI 293a-0101 Z Chikungunya virus IgA, IgG, IgM 0.1 ml 5.00negative control

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CW 2080-5001 A antibodies against Helicobacter pylori IgA 0.1 ml 8.00IgA positive control

CW 2080-5001 G antibodies against Helicobacter pylori IgG 0.1 ml 8.00IgG positive control

CW 2080-5001 ZA antibodies against Helicobacter pylori IgA 0.1 ml 8.00IgA negative control

CW 2080-5001 ZG antibodies against Helicobacter pylori IgG 0.1 ml 8.00IgG negative control

CW 2111-5001 YM antibodies against Treponema pallidum IgM 0.1 ml 8.00IgM weakly reactive control

CW 2131-5001 G antibodies against Borrelia afzelii IgG 0.1 ml 8.00IgG positive control

(Westernblot/EUROLINE-WB)

CW 2131-5001 M antibodies against Borrelia afzelii IgM 0.1 ml 8.00IgM positive control

(Westernblot/EUROLINE-WB)

CW 2131-5001 YM antibodies against Borrelia afzelii IgM 0.1 ml 8.00IgM weakly reactive control

(Westernblot/EUROLINE-WB)

CW 2131-5001 ZG antibodies against Borrelia afzelii IgG 0.1 ml 8.00IgG negative control

(Westernblot/EUROLINE-WB)

CW 2131-5001 ZM antibodies against Borrelia afzelii IgM 0.1 ml 8.00IgM negative control

(Westernblot/EUROLINE-WB)

CW 2131-5001-2 G antibodies against Borrelia afzelii IgG 0.1 ml 8.00IgG positive control 2

(Westernblot/EUROLINE-WB)

CW 2132-5001 G antibodies against Borrelia burgdorferi IgG 0.1 ml 8.00IgG positive control

CW 2132-5001 M antibodies against Borrelia burgdorferi IgM 0.1 ml 8.00IgM positive control

CW 2132-5001 YM antibodies against Borrelia burgdorferi IgM 0.1 ml 8.00IgM weakly reactive control

CW 2132-5001 ZG antibodies against Borrelia burgdorferi IgG 0.1 ml 8.00IgG negative control

CW 2132-5001 ZM antibodies against Borrelia burgdorferi IgM 0.1 ml 8.00IgM negative control

CW 2134-5001 G antibodies against Borrelia garinii IgG 0.1 ml 8.00IgG positive control

CW 2134-5001 M antibodies against Borrelia garinii IgM 0.1 ml 8.00IgM positive control

CW 2134-5001 YM antibodies against Borrelia garinii IgM 0.1 ml 8.00IgM weakly reactive control

CW 2134-5001 ZG antibodies against Borrelia garinii IgG 0.1 ml 8.00IgG negative control

CW 2134-5001 ZM antibodies against Borrelia garinii IgM 0.1 ml 8.00IgM negative control

CW 2173-5001 A antibodies against Yersinia enterocolitica IgA 0.1 ml 8.00IgA positive control

(for diagnosing various forms of arthritis)

CW 2173-5001 G antibodies against Yersinia enterocolitica IgG 0.1 ml 8.00IgG positive control

(for diagnosing various forms of arthritis)

Price (€)Control

(50-fold concentrate)

FormatOrder No.

Controls for EUROIMMUN Westernblots/EUROLINE-WB

Ig Class

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Price (€)Control

(50-fold concentrate)

FormatOrder No.

Controls for EUROIMMUN Westernblots/EUROLINE-WB

Ig Class

CW 2173-5001 YA antibodies against Yersinia enterocolitica IgA 0.1 ml 8.00IgA weakly reactive control

(for diagnosing various forms of arthritis)

CW 2173-5001 ZA antibodies against Yersinia enterocolitica IgA 0.1 ml 8.00IgA negative control

(for diagnosing various forms of arthritis)

CW 2173-5001 ZG antibodies against Yersinia enterocolitica IgG 0.1 ml 8.00IgG negative control

(for diagnosing various forms of arthritis)

CW 2531-5001 G antibodies against Herpes simplex virus (HSV) IgG 0.1 ml 8.00IgG positive control

CW 2531-5001 ZG antibodies against Herpes simplex virus (HSV) IgG 0.1 ml 8.00IgG negative control

CW 2531-5001 ZM antibodies against Herpes simplex virus (HSV) IgM 0.1 ml 8.00IgM negative control

CW 2790-5001 G antibodies against Epstein-Barr virus (EBV) IgG 0.1 ml 8.00IgG positive control

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If requested the EUROASSAY can be manufactured individually, thus offering special antigen combinations, e.g. dsDNA, histones, nucleosomes, PM-Scl,nRNP/Sm, Sm, SS-A (60 kDa), Ro-52, SS-B, Scl-70, Jo-1, ribosomal P-proteins, centromere protein B, AMA M2, M4, M9, SLA/LP, LC-1, LKM-1. Slides with onlyone field can be delivered as special format.

DA 1010-1003-1 G thyroid peroxidase (TPO) IgG EUROASSAY strip 10 x 03 8.30 249.00DA 1010-1005-1 G thyroglobulin (TG) with antigens 10 x 05 8.00 400.00

DA 1200-1003-2 G myeloperoxidase (MPO) IgG EUROASSAY strip 10 x 03 8.30 249.00DA 1200-1005-2 G proteinase 3 (PR3) with antigens 10 x 05 8.00 400.00

DA 1300-1003 G AMA M2, LKM-1, SLA/LP IgG EUROASSAY strip 10 x 03 9.90 297.00with antigens

DA 1300-1003-2 G LKM-1, LC-1, SLA/LP IgG EUROASSAY strip 10 x 03 9.90 297.00DA 1300-1005-2 G with antigens 10 x 05 9.50 475.00

DA 1300-1003-3 G Liver Profile IgG EUROASSAY strip 10 x 03 11.40 342.00AMA M2, LKM-1, LC-1, SLA/LP with antigens

DA 1590-1003-1 G Anti-ENA ProfilePlus IgG EUROASSAY strip 10 x 03 14.60 438.00DA 1590-1005-1 G (nRNP/Sm, Sm, SS-A, SS-B, Scl-70, with antigens 10 x 05 14.00 700.00

Jo-1 separately)

DA 1590-1003-2 G Anti-ENA ProfilePlus with AMA M2 IgG EUROASSAY strip 10 x 03 16.10 483.00(nRNP/Sm, Sm, SS-A, SS-B, Scl-70, with antigens

Jo-1, AMA M2 separately)

DA 1590-1003-3 G SLE Profile IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-3 G (nRNP/Sm, Sm, SS-A, SS-B, dsDNA, with antigens 10 x 05 15.50 775.00

histones, ribosomal P-proteins separately)

DA 1590-1003-6 G Anti-ENA ProfilePlus with dsDNA IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-6 G (nRNP/Sm, Sm, dsDNA, Jo-1, with antigens 10 x 05 15.50 775.00

SS-A, SS-B, Scl-70 separately)

DA 1590-1003-9 G Anti ENA Profile IgG EUROASSAY strip 10 x 03 11.40 342.00DA 1590-1005-9 G (nRNP/Sm, Sm, SS-A, SS-B separately) with antigens 10 x 05 11.00 550.00

DA 1590-1003-18 G Anti-ENA ProfilePlus with centromere protein B IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-18 G (nRNP/Sm, Sm, SS-A, SS-B, Scl-70, with antigens 10 x 05 15.50 775.00

Jo-1, centromere protein B separately)

DA 1590-1003-20 G Anti-ENA ProfilePlus with histones IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-20 G (nRNP/Sm, Sm, SS-A, SS-B, Scl-70, with antigens 10 x 05 15.50 775.00

Jo-1, histones separately)

DA 1590-1003-25 G Anti-ENA ProfilePlus with PM-Scl IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-25 G (nRNP/Sm, Sm, SS-A, SS-B, Scl-70, with antigens 10 x 05 15.50 775.00

Jo-1, PM-Scl separately)

DA 1590-1003-27 G SLE Profile 2 IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-27 G (nRNP/Sm, Sm, SS-A, SS-B, dsDNA, with antigens 10 x 05 15.50 775.00

histones, nucleosomes separately)

DA 1590-1003-28 G SLE Profile 3 IgG EUROASSAY strip 10 x 03 11.40 342.00DA 1590-1005-28 G (dsDNA, histones, nucleosomes, with antigens 10 x 05 11.00 550.00

ribosomal P-proteins separately)

DA 1590-1003-29 G Anti-ENA ProfilePlus with Ro-52 IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-29 G (nRNP/Sm, Sm, SS-A, SS-B, Scl-70, with antigens 10 x 05 15.50 775.00

Jo-1, Ro-52 separately)

DA 1590-1003-30 G Scl-70, Jo-1, PM-Scl IgG EUROASSAY strip 10 x 03 9.90 297.00DA 1590-1005-30 G with antigens 10 x 05 9.50 475.00

DA 1590-1003-32 G Anti-ENA ProfilePlus with ribosomal P-proteins IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-32 G (nRNP/Sm, Sm, SS-A, SS-B, Scl-70, with antigens 10 x 05 15.50 775.00

Jo-1, ribosomal P-proteins separately)

DA 1590-1003-33 G Anti-ENA ProfilePlus with nucleosomes IgG EUROASSAY strip 10 x 03 16.10 483.00DA 1590-1005-33 G (nRNP/Sm, Sm, nucleosomes, Jo-1, with antigens 10 x 05 15.50 775.00

SS-A, SS-B, Scl-70 separately)

DA 1620-1003-1 O AMA Profile IgGM EUROASSAY strip 10 x 03 9.90 297.00(AMA M2, M4, M9 separately) with antigens

Price (€)

per Kit

Antibodies

against

SubstrateIg Class Format

Slides x Fields

Order No. Price (€)

per Field

EUROASSAY for the Determination of Autoantibodies (Test Systems)

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SubstrateIg Class FormatOrder No. Price (€)per Strip

EUROLINE for the Determination of Autoantibodies (Test Systems)

DL 1111-1601 G Neuronal Antigens Profile IgG membrane strip with antigens 16 x 01 24.00 384.00(amphiphysin, CV2, PNMA2 (Ma-2), (EUROLINE)

Ri, Yo, Hu separately)

DL 1130-1601-1 G Gangliosides Profile 1 IgG membrane strip with antigens 16 x 01 9.50 152.00(GM1, GD1b, GQ1b separately) (EUROLINE)

DL 1130-1601-1 M Gangliosides Profile 1 IgM membrane strip with antigens 16 x 01 9.50 152.00(GM1, GD1b, GQ1b separately) (EUROLINE)

DL 1130-1601-2 G Gangliosides Profile 2 IgG membrane strip with antigens 16 x 01 14.50 232.00(GM1, GM2, GM3, GD1a, GD1b, GT1b, GQ1b separately) (EUROLINE)

DL 1130-1601-2 M Gangliosides Profile 2 IgM membrane strip with antigens 16 x 01 14.50 232.00(GM1, GM2, GM3, GD1a, GD1b, GT1b, GQ1b separately) (EUROLINE)

DL 1200-1601-2 G myeloperoxidase (MPO) IgG membrane strip with antigens 16 x 01 8.00 128.00proteinase 3 (PR3) (EUROLINE)

DL 1200-1601-3 G myeloperoxidase (MPO) IgG membrane strip with antigens 16 x 01 9.50 152.00proteinase 3 (PR3) (EUROLINE)

glomerular basement membrane (GBM)

DL 1300-1601-3 G Liver Profile IgG membrane strip with antigens 16 x 01 11.00 176.00(AMA M2, LKM-1, LC-1, SLA/LP separately) (EUROLINE)

DL 1300-1601-4 G Profile Autoimmune Liver Diseases IgG membrane strip with antigens 16 x 01 18.50 296.00(AMA M2, 3E (BPO), Sp100, PML, gp210, (EUROLINE)LC-1, LKM-1, SLA/LP, Ro-52 separately)

DL 1530-1601 G Myositis Profile IgG membrane strip with antigens 16 x 01 22.00 352.00(Mi-2, Ku, PM-Scl, Jo-1, PL-7, (EUROLINE)

PL-12, Ro-52 separately)

DL 1590-1601-1 G Anti-ENA ProfilePlus 1 IgG membrane strip with antigens 16 x 01 14.00 224.00(nRNP/Sm, Sm, SS-A, Ro-52, SS-B, (EUROLINE)

Scl-70, Jo-1 separately)

DL 1590-1601-3 G ANA Profile 3 IgG membrane strip with antigens 16 x 01 17.50 280.00(nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Scl-70, (EUROLINE)

PM-Scl, Jo-1, centromere protein B, PCNA, dsDNA, nucleosomes,histones, ribosomal P-proteins, AMA M2 separately)

DL 1590-1601-8 G ANA Profile 1 IgG membrane strip with antigens 16 x 01 16.00 256.00(nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Scl-70, (EUROLINE)

Jo-1, centromere protein B, dsDNA, nucleosomes,histones, ribosomal P-proteins separately)

Price (€)

per Kit

Antibodies

against

SubstrateIg Class Format

Slides x Fields

Order No. Price (€)

per Field

EUROASSAY for Allergology (Test Systems)

DE 3110-1003 E * allergy profile inhalation IgE EUROASSAY strip 10 x 03 16.10 483.00DE 3110-1005 E * (gx, t3, w6, d1, e1, e2, m2) with allergens 10 x 05 15.50 775.00

DE 3410-1003 E * allergy profile food IgE EUROASSAY strip 10 x 03 16.10 483.00DE 3410-1005 E * (f1, f2, f3, f4, f13, f14, f17) with allergens 10 x 05 15.50 775.00

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SubstrateIg Class FormatOrder No. Price (€)per Strip

EUROLINE for Allergology (Test Systems)

DP 3110-1601 E allergy profile inhalation IgE membrane strip with allergens 16 x 01 21.00 336.00(g1, g3, g6, g12, t2, t3, t4, t7, w1, w6, w9, (EUROLINE)

d1, d2, e1, e2, e3, m1, m2, m3, m6)

DP 3111-1601 E allergy profile pediatric inhalation IgE membrane strip with allergens 16 x 01 21.00 336.00(g6, g12, t2, t3, t4, w6, w8, w9, d1, d2, (EUROLINE)

e1, e2, e3, e6, e82, e84, m1, m2, m3, m6)

DP 3112-1601 E allergy profile Mediterranean inhalation IgE membrane strip with allergens 16 x 01 21.00 336.00(g2, g6, t3, t4, t9, t11, t23, t210, w1, w6, w9, w19, (EUROLINE)

d1, d2, d70, e1, e2, e3, m2, m6)

DP 3113-1601 E allergy profile inhalation “South East Asia” IgE membrane strip with allergens 16 x 01 21.00 336.00(gs1, ts19, t104, t119, t223, ds1, i6, e1, e2, es172, e6, (EUROLINE)

e71, e82, e84, ms1, ms4, m5, m12, m45, u134)

DP 3114-1601 E * allergy profile inhalation “Korea 1” IgE membrane strip with allergens 16 x 01 21.00 336.00(g2, g3, g6, g12, ts3, ts11, ts14, ts15, t4, t7, t12, t19, t71, (EUROLINE)

w100, f1, f2, f14, f23, f234, f95)

DP 3115-1601 E * allergy profile inhalation “Korea 2” IgE membrane strip with allergens 16 x 01 21.00 336.00(w1, w6, w8, w11, w14, w12, m1, m2, m3, m6, e1, e2, (EUROLINE)

i6, h1, d1, d2, g7, ts4, t1, t16)

DP 3116-1601 E * allergy profile inhalation “China” IgE membrane strip with allergens 16 x 01 21.00 336.00(gs23, ts21, t3, t8, t11, t12, t14, t70, ws18, w1, w6, (EUROLINE)

w9, es1, d1, d2, i6, ms5, m1, u73, u80)

DP 3117-1601 E * allergy profile inhalation “Middle East” IgE membrane strip with allergens 16 x 01 21.00 336.00(g1, g6,g12, t2, t3, t7, t9, w1, w6, w8, d1, d2, i6, e1, (EUROLINE)

e84, m1, m2, m3, m5, m6)

DP 3118-1601 E * allergy profile inhalation “Gulf” IgE membrane strip with allergens 16 x 01 21.00 336.00(g6, g12, t2, t3, t7, t9, w1, w6, d1, d2, i6, (EUROLINE)

e1, e2, e3, e17, m1, m2, m3, m5, m6)

DP 3410-1601 E allergy profile food IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f75, f2, f45, f4, f5, f9, f13, f14, f17, f20, (EUROLINE)

f49, f84, f237, f25, f31, f35, f85, f3, f23)

DP 3411-1601 E allergy profile food “South East Asia 1” IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f75, f2, f4, f9, f10, f14, f13, f17, f63, f64, f83, (EUROLINE)

fs10, fs14, f23, f24, f80, f179, f105, f336)

DP 3411-1601-1 E * allergy profile food “South East Asia 2” IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f75, f2, f4, f9, f10, f14, f13, f17, f63, f340, f83, fs10, (EUROLINE)

fs14, f23, f24, f80, f179, f105, f336)

DP 3412-1601 E * allergy profile food “Korea 1” IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f2, f14, f81, f3, f23, f40, f41, f234, f26, f27, f83, fs15, (EUROLINE)

f95, f4, f6, f9, f292, f47, f48)

Price (€)

per Kit

Antibodies

against

SubstrateIg Class FormatOrder No. Price (€)

per Strip

EUROLINE for Infectious Serology (Test Systems)

DN 2260-1601-1 G Malaria Profile 1 IgG membrane strip with antigens 16 x 01 11.00 176.00(Plasmodium falciparum HRP-2 and MSP-2, (EUROLINE)Plasmodium vivax MSP and CSP separately)

DN 2410-1601-3 G * “TO.R.C.H. Profile” IgG membrane strip with antigens 16 x 01 12.50 200.00(Toxoplasma gondii, Rubella virus, (EUROLINE)

CMV, HSV-1, HSV-2 separately)

DN 2410-1601-3 M * “TO.R.C.H. Profile” IgM membrane strip with antigens 16 x 01 12.50 200.00(Toxoplasma gondii, Rubella virus, (EUROLINE)

CMV, HSV-1, HSV-2 separately)

DN 2790-1601-2 G EBV Profile 2 IgG membrane strip with antigens 16 x 01 12.00 192.00(VCA gp125, VCA p19, (EUROLINE)

EBNA-1, p22, EA-D separately)

DN 2790-1601-2 M EBV Profile 2 IgM membrane strip with antigens 16 x 01 12.00 192.00(VCA gp125, VCA p19, (EUROLINE)

EBNA-1, p22, EA-D separately)

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Antigen andAntigen Source

Ig Class FormatOrder No. Price (€)per Strip

Westernblot/EUROLINE-WB for the Determination of Autoantibodies (Test Systems)

DW 1111-1601-2 G EUROLINE-WB whole antigen, SDS extract IgG 16 x 01 24.00 384.00DW 1111-2401-2 G neuronal antigens (Hu, Yo, Ri) of primate cerebellum 24 x 01 24.00 576.00

plus recombinant Hu, Yo and Ri plus recombinant Hu, Yo and Ri

DW 1520-1601-3 G EUROLINE-WB whole antigen, SDS extract IgG 16 x 01 16.00 256.00DW 1520-3001-3 G HEp-2 cell antigens of HEp-2 cells plus native SS-A 30 x 01 16.00 480.00

(nucleolar, cytoplasmic, mitochondrial) and recombinant CENP B and Ro-52plus CENP B, SS-A and Ro-52

DW 1530-1601-2 G EUROLINE-WB whole antigen, SDS extract of IgG 16 x 01 22.00 352.00Myositis HeLa cells plus recombinant

(Mi-2, Ku plus recombinant PM-Scl, PM-Scl, PL-7, PL-12 and native Jo-1PL-7, PL-12 and native Jo-1)

Price (€)

per Kit

Antibodies

against

SubstrateIg Class FormatOrder No. Price (€)

per Strip

EUROLINE for Allergology (Test Systems)

DP 3413-1601 E * allergy profile food “Korea 2” IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f2, f14, f81, f3, f23, f40, f41, f234, f26, f27, f83, fs15, (EUROLINE)

f95, f4, f6, f9, f292, f47, f48)

DP 3414-1601 E * allergy profile food “China” IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f2, f4, f7, f27, f88, fs35, f13, f14, fs40, f25, f292, (EUROLINE)

fs42, f23, f234, f3, f41, f56, fs41, fs77)

DP 3415-1601 E * allergy profile food “Middle East” IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f75, f2, f78, e204, f4, f14, f45, f13, f17, f20, f33, f49, (EUROLINE)

f29, f25, f31, f85, f48, f89, f88)

DP 3416-1601 E * allergy profile food “Gulf” IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f75, f2, f105, f4, f14, f45, fs36, f13, f29, f33, (EUROLINE)

f44, f93, f25, f31, f48, f83, f88, f3, f23)

DP 3417-1601 E * allergy profile food “Cyprus 1” IgE membrane strip with allergens 16 x 01 21.00 336.00(f1, f2, f75, f76, f77, f78, f81, f4, f45, f5, f14, (EUROLINE)

f7, f79, f9, f10, f13, f144, f17, f20, f49)

DP 3418-1601 E * allergy profile food “Cyprus 2” IgE membrane strip with allergens 16 x 01 21.00 336.00(f177, f23, f234, f24, f258, f3, f37, f40, f41, f80, (EUROLINE)

f48, f108, f132, f212, f25, f292, f31, f35, f47, f96)

DP 3419-1601 E * allergy profile food “Cyprus 3” IgE membrane strip with allergens 16 x 01 21.00 336.00(f26, f63, f83, f88, f237, f29, f32, f328, f33, f44, f49, (EUROLINE)

f72, f84, f95, f281, f86, f89, f90, f105, f93)

DP 3710-1601 E allergy profile atopy IgE membrane strip with allergens 16 x 01 21.00 336.00(g6, g12, t3, w6, d1, e1, e2, e3, m2, m6, f1, f2, (EUROLINE)

f3, f4, f9, f14, f17, f31, f35, f49)

DP 3711-1601 E allergy profile pollen-food cross reactions IgE membrane strip with allergens 16 x 01 21.00 336.00(g6, t3, w6, f4, f5, f13, f17, f20, f48, f89, f271, f275, (EUROLINE)

f44, f49, f348, f237, f328, f31, f35, f85)

DP 3712-1601 E allergy profile pediatrics IgE membrane strip with allergens 16 x 01 21.00 336.00(gx, t3, w6, d1, d2, e1, e2, e3, m2, m3, m6,f1, f2, f3, (EUROLINE)

f4, f9, f13, f14, f17, f31, f35, f49, f75, f76, f77, f78)

DP 3713-1601 E allergy profile atopy “China” IgE membrane strip with allergens 16 x 01 21.00 336.00(ts20, w1, w6, ds1, h1, e1, e2, i6, ms1, u80, f1, f2, f13, (EUROLINE)

f14, f27, f88, fs33, fs34, f23, f234)

DP 3713-1601-2 E allergy profile atopy “China 2” IgE membrane strip with allergens 16 x 01 17.00 272.00(w18, w6, u80, ds1, es1, ms5, f245, (EUROLINE)

fs56, fs43, fs42, fs34)

DP 3713-1601-3 E * allergy profile atopy “China 3” IgE membrane strip with allergens 16 x 01 18.00 288.00(ts22, w6, us1, ds1, es1, h1, ms5, f245, fs9, fs43, (EUROLINE)

fs56, fs34, fs44)

DP 3720-1601 E allergy profile insect venoms IgE membrane strip with allergens 16 x 01 8.00 128.00(i1, i3) (EUROLINE)

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Antigen Source

Ig Class FormatOrder No. Price (€)

per Strip

Westernblot/EUROLINE-WB for Infectious Serology (Test Systems)

DY 2080-1601 A Helicobacter pylori whole antigen, IgA 16 x 01 10.00 160.00DY 2080-3001 A SDS extract 30 x 01 10.00 300.00

DY 2080-1601 G Helicobacter pylori whole antigen, IgG 16 x 01 10.00 160.00DY 2080-3001 G SDS extract 30 x 01 10.00 300.00

DY 2111-1601 G Treponema pallidum 15 kDa, 17 kDa, IgG 16 x 01 10.00 160.00DY 2111-2401 G 45 kDa (tmpA), 47 kDa 24 x 01 10.00 240.00

DY 2111-1601 M Treponema pallidum 15 kDa, 17 kDa, IgM 16 x 01 10.00 160.00DY 2111-2401 M 45 kDa (tmpA), 47 kDa 24 x 01 10.00 240.00

DY 2111-1601-1 G EUROLINE-WB 15 kDa, 17 kDa, 45 kDa (tmpA) 47 kDa, IgG 16 x 01 14.00 224.00DY 2111-2401-1 G Treponema pallidum plus purified cardiolipin 24 x 01 14.00 336.00

plus cardiolipin

DY 2111-1601-1 M EUROLINE-WB 15 kDa, 17 kDa, 45 kDa (tmpA) 47 kDa, IgM 16 x 01 14.00 224.00DY 2111-2401-1 M Treponema pallidum plus purified cardiolipin 24 x 01 14.00 336.00

plus cardiolipin

DY 2131-1601 G Borrelia afzelii whole antigen, SDS extract of IgG 16 x 01 10.00 160.00DY 2131-3001 G Borrelia afzelii 30 x 01 10.00 300.00DY 2131-3201 G 32 x 01 9.38 300.00DY 2131-24001 G 240 x 01 10.00 2,400.00

DY 2131-1601 M Borrelia afzelii whole antigen, SDS extract of IgM 16 x 01 10.00 160.00DY 2131-3001 M Borrelia afzelii 30 x 01 10.00 300.00DY 2131-3201 M 32 x 01 9.38 300.00DY 2131-24001 M 240 x 01 10.00 2,400.00

DY 2131-1601-1 G EUROLINE-WB whole antigen, SDS extract of IgG 16 x 01 14.00 224.00DY 2131-3001-1 G Borrelia Borrelia afzelii plus VlsE 30 x 01 14.00 420.00DY 2131-24001-1 G 240 x 01 14.00 3,360.00

DY 2131-1601-1 M EUROLINE-WB whole antigen, SDS extract of IgM 16 x 01 14.00 224.00DY 2131-3001-1 M Borrelia Borrelia afzelii plus VlsE 30 x 01 14.00 420.00DY 2131-24001-1 M 240 x 01 14.00 3,360.00

DY 2132-1601 G Borrelia burgdorferi whole antigen, SDS extract of IgG 16 x 01 10.00 160.00DY 2132-3001 G Borrelia burgdorferi sensu stricto 30 x 01 10.00 300.00DY 2132-3201 G 32 x 01 9.38 300.00DY 2132-24001 G 240 x 01 10.00 2,400.00

DY 2132-1601 M Borrelia burgdorferi whole antigen, SDS extract of IgM 16 x 01 10.00 160.00DY 2132-3001 M Borrelia burgdorferi sensu stricto 30 x 01 10.00 300.00DY 2132-3201 M 32 x 01 9.38 300.00DY 2132-24001 M 240 x 01 10.00 2,400.00

DY 2134-1601 G Borrelia garinii whole antigen, SDS extract IgG 16 x 01 10.00 160.00DY 2134-3001 G of Borrelia garinii 30 x 01 10.00 300.00DY 2134-3201 G 32 x 01 9.38 300.00DY 2134-24001 G 240 x 01 10.00 2,400.00

DY 2134-1601 M Borrelia garinii whole antigen, SDS extract of IgM 16 x 01 10.00 160.00DY 2134-3001 M Borrelia garinii 30 x 01 10.00 300.00DY 2134-3201 M 32 x 01 9.38 300.00DY 2134-24001 M 240 x 01 10.00 2,400.00

DY 2173-1601 A Yersinia enterocolitica isolated virulence factors IgA 16 x 01 10.00 160.00DY 2173-3001 A Detection of antibodies against virulence factors of the (release proteins, Yop) 30 x 01 10.00 300.00

Yersinia enterocolitica pathogen in human serum of Yersinia enterocolitica(for diagnosing various forms of arthritis).

DY 2173-1601 G Yersinia enterocolitica isolated virulence factors IgG 16 x 01 10.00 160.00DY 2173-3001 G Detection of antibodies against virulence factors of the (release proteins, Yop) 30 x 01 10.00 300.00

Yersinia enterocolitica pathogen in human serum of Yersinia enterocolitica(for diagnosing various forms of arthritis).

DY 2320-1601 G Echinococcus granulosus whole antigen, IgG 16 x 01 10.00 160.00DY 2320-2401 G SDS extract 24 x 01 10.00 240.00

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Antigen Source

Ig Class FormatOrder No. Price (€)

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Westernblot/EUROLINE-WB for Infectious Serology (Test Systems)

DY 2531-1601-1 G EUROLINE-WB whole antigen, SDS extract of the IgG 16 x 01 10.00 160.00DY 2531-2401-1 G Herpes simplex virus 1 (HSV-1) HSV-1 strain “McIntire” plus gG2 24 x 01 10.00 240.00

plus HSV-2 type-specific purified by affinity chromatographyglycoprotein G2

DY 2531-1601-1 M EUROLINE-WB whole antigen, SDS extract of the IgM 16 x 01 10.00 160.00DY 2531-2401-1 M Herpes simplex virus 1 (HSV-1) HSV-1 strain “McIntire” plus gG2 24 x 01 10.00 240.00

plus HSV-2 type-specific purified by affinity chromatographyglycoprotein G2

DY 2570-1601 G * Cytomegalovirus whole antigen, IgG 16 x 01 10.00 160.00DY 2570-2401 G * (CMV) SDS extract 24 x 01 10.00 240.00

DY 2570-1601 M * Cytomegalovirus whole antigen, IgM 16 x 01 10.00 160.00DY 2570-2401 M * (CMV) SDS extract 24 x 01 10.00 240.00

DY 2790-1601 G Epstein-Barr virus whole antigen, IgG 16 x 01 10.00 160.00DY 2790-2401 G (EBV) SDS extract 24 x 01 10.00 240.00

DY 2790-1601 M Epstein-Barr virus whole antigen, IgM 16 x 01 10.00 160.00DY 2790-2401 M (EBV) SDS extract 24 x 01 10.00 240.00

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Antibodies

against

Antigen and

Antigen Source

Ig Class FormatOrder No. Price (€)

per Well

Microplate ELISA for the Determination of Autoantibodies (Test Systems)

Calibration

EA 1012-9601 G thyroid peroxidase recombinant, expression with IgG 10/50/500 IU/ml 96 x 01 2.92 280.00(TPO) Baculovirus vector in insect cells

EA 1013-9601 G thyroglobulin native, human IgG 20/100/1000 IU/ml 96 x 01 2.92 280.00(TG) thyroid gland

EA 1015-9601 G TSH receptor native, IgG 0/1/2/8/40 IU/l 96 x 01 3.96 380.00(thyrotropin receptor) porcine thyrocytes

EA 1015-9601-1 G TSH receptor native, IgG 0.1/1/2/8/40 IE/l 96 x 01 3.96 380.00(thyrotropin receptor) porcine thyrocytes

Fast ELISA

EA 1022-9601 G GAD recombinant IgG 5/15/35/120/ 96 x 01 3.96 380.00glutamic acid decarboxylase 250/2000 IU/ml

EA 1022-9601-1 G GAD/IA2 Pool recombinant IgG 4/10/20/70/ 96 x 01 4.38 420.00glutamic acid decarboxylase/ 145/450 IU/ml

tyrosine phosphatase

EA 1023-9601 G IA2 recombinant IgG 15/60/200/400/ 96 x 01 3.96 380.00tyrosine phosphatase 4000 IU/ml

EA 1200-1208-1 G ANCA Profile (proteinase 3, MPO, elastase, native, human IgG semi-quantitative 12 x 08 3.44 330.00cathepsin G, BPI, lactoferrin separately) neutrophil granulocytes

EA 1201-9601 G cANCA: native, human IgG 2/20/200 RU/ml 96 x 01 2.92 280.00proteinase 3 neutrophil granulocytes

EA 1201-9601-1 G cANCA: native, human IgG 2/20/200 RU/ml 96 x 01 3.33 320.00proteinase 3 neutrophil granulocytes(capture test)

EA 1201-9601-2 G cANCA: native, human IgG 2/20/200 RU/ml 96 x 01 3.33 320.00proteinase 3 neutrophil granulocytes(PR3-hn-hr) recombinant, human c-DNA

expressed in human cell line

EA 1211-9601 G pANCA: native, human IgG 2/20/200 RU/ml 96 x 01 2.92 280.00myeloperoxidase (MPO) neutrophil granulocytes

EA 1251-9601 G glomerular basement membrane alpha-3-chain of type IV collagen, IgG 2/20/200 RU/ml 96 x 01 3.23 310.00(GBM) incl. NC1 domain, from bovine kidney

EA 1302-9601 G soluble liver antigen/ recombinant SLA/LP IgG 2/20/200 RU/ml 96 x 01 3.75 360.00liver-pancreas antigen (SLA/LP) expression in E. coli

EA 1307-9601 G cytosolic recombinant formiminotransferase- IgG semi-quantitative 96 x 01 3.23 310.00liver antigen type 1 cyclodeaminase, expression with

(LC-1) baculovirus vector in insect cells

EA 1321-9601 G liver-kidney microsomes recombinant cytochrome P450 IID6, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00LKM-1 expression with baculovirus vector

in insect cells

EA 1361-9601 G parietal cells native, H+/K+ ATPase, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00(PCA) porcine gastric mucosa

EA 1362-9601 G intrinsic factor native, porcine IgG 2/20/200 RU/ml 96 x 01 2.92 280.00gastric mucosa

EA 1502-4801-2 G BP180-4X recombinant, expression in E. coli, IgG 2/20/200 RU/ml 48 x 01 4.17 200.00tetramer of the NC16A domain

EA 1505-9601 G cyclic citrullinated peptides highly purified synthetic IgG 1/5/20/100/200 RU/ml 96 x 01 4.69 450.00(CCP) CCP (second generation)

EA 1560-9601 G histones native, mixture of individually isolated IgG 2/20/200 RU/ml 96 x 01 2.92 280.00histone types H1/H2a/H2b/H3/H4, bovine

EA 1571-9601 G double-stranded DNA highly purified genomic IgG 10/100/800 IU/ml 96 x 01 2.92 280.00(dsDNA) double-stranded DNA

EA 1572-9601 G dsDNA-NcX highly purified genomic IgG 10/100/800 IU/ml 96 x 01 2.92 280.00double-stranded DNA,

complexed with nucleosomes

EA 1573-9601 G C1q native, IgG 2/20/200 RU/ml 96 x 01 3.75 360.00human C1q

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Price (€)

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Antibodies

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Antigen Source

Ig Class FormatOrder No. Price (€)

per Well

Microplate ELISA for the Determination of Autoantibodies (Test Systems)

Calibration

EA 1574-9601 G nucleosomes native, nucleosomes, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00calf thymus

EA 1576-9601 G single-stranded DNA heat-denatured ssDNA IgG 2/20/200 RU/ml 96 x 01 2.92 280.00(ssDNA)

EA 1584-9601 G PM-Scl recombinant, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00expression in E. coli

EA 1590-1208-1 G Anti-ENA ProfilePlus 1 (nRNP/Sm, see individual ELISA IgG semi-quantitative 12 x 08 3.23 310.00Sm, SS-A, SS-B, Scl-70, Jo-1 separately)

EA 1590-1208-2 G Anti-ENA ProfilePlus 2 (ribosomal see individual ELISA IgG semi-quantitative 12 x 08 3.44 330.00P-proteins, nRNP/Sm, Sm, SS-A, SS-B,Scl-70, Jo-1, centromere, separately)

EA 1590-1208-3 G Anti-ENA SLE Profile 1 (dsDNA, histones, see individual ELISA IgG semi-quantitative 12 x 08 3.44 330.00ribosomal P-proteins, nRNP/Sm, Sm,

SS-A, SS-B, Scl-70 separately)

EA 1590-9601-7 G Anti-ENA PoolPlus (antigen mixture: see individual ELISA IgG semi-quantitative 96 x 01 3.75 360.00nRNP/Sm, Sm, SS-A, SS-B, Scl-70, Jo-1)

EA 1590-9601-8 G ANA screen (antigen mixture: dsDNA, see individual ELISA IgG semi-quantitative 96 x 01 4.79 460.00histones, ribosomal P-proteins, nRNP/Sm,Sm, SS-A, SS-B, Scl-70, Jo-1, centromere)

EA 1590-9601-9 G * Anti-ENA Pool (antigen mixture: see individual ELISA IgG semi-quantitative 96 x 01 3.85 370.00nRNP/Sm, Sm, SS-A, SS-B, Scl-70,

ribosomal P-proteins, Ro-52)

EA 1590-9601-10 G ANA VarioProfile (optionally histones, see individual ELISA IgG semi-quantitative 96 x 01 3.44 330.00dsDNA, nucleosomes, ssDNA, PM-Scl,

nRNP/Sm, Sm, SS-A, SS-B, Scl-70, ribosomalP-proteins, Jo-1, AMA M2, centromere)

maximum 4 different microplate strips

EA 1590-9601-11 G *ANA screen 11 (antigen mixture: PCNA, PM-Scl,see individual ELISA IgG semi-quantitative 96 x 01 4.79 460.00ribosomal P-proteins, nRNP/Sm, Sm,

SS-A, Ro-52, SS-B, Scl-70, Jo-1,centromere)

EA 1590-1208-12 G Anti-ENA SLE Profile 2 (dsDNA, histones, see individual ELISA IgG semi-quantitative 12 x 08 3.44 330.00nucleosomes, nRNP/Sm, Sm,SS-A, SS-B, Scl-70 separately)

EA 1590-9601-14 G *ANA screen 9 (antigen mixture: PCNA, PM-Scl,see individual ELISA IgG semi-quantitative 96 x 01 4.17 400.00ribosomal P-proteins, nRNP/Sm, Sm,

SS-A, SS-B, Scl-70, Jo-1)

EA 1591-9601 G nRNP/Sm native, U1-nRNP, incl. 70K, A, C, B, B’, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00D, E, F, G, calf thymus

EA 1593-9601 G Sm native, U2, U4, U5, U6-nRNP, incl. B, B’, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00D, E, F, G, bovine thymus

EA 1595-9601 G SS-A (Ro) native, SS-A-specific proteins (60 kDa), IgG 2/20/200 RU/ml 96 x 01 2.92 280.00bovine spleen and thymus

EA 1597-9601 G SS-B (La) native, SS-B-specific protein (48 kDa), IgG 2/20/200 RU/ml 96 x 01 2.92 280.00calf and rabbit thymus

EA 1599-9601 G Scl-70 native, DNA topoisomerase I, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00calf thymus

EA 1611-9601 G centromeres recombinant centromere protein B, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00expression with baculovirus vector

in insect cells

EA 1621-9601 A cardiolipin (AMA M1) native, IgA 2/12/120 PL IgA U/ml 96 x 01 2.92 280.00bovine heart

EA 1621-9601 G cardiolipin (AMA M1) native, IgG 2/12/120 PL IgG U/ml 96 x 01 2.92 280.00bovine heart

EA 1621-9601 M cardiolipin (AMA M1) native, IgM 2/12/120 PL IgM U/ml 96 x 01 2.92 280.00bovine heart

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Price (€)

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Antibodies

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Antigen and

Antigen Source

Ig Class FormatOrder No. Price (€)

per Well

Microplate ELISA for the Determination of Autoantibodies (Test Systems)

Calibration

EA 1621-9601 P cardiolipin (AMA M1) native, IgAGM 2/12/120 RU/ml 96 x 01 2.92 280.00bovine heart

EA 162a-9601 A phosphatidylserine native, IgA 2/12/120 RU/ml 96 x 01 2.92 280.00bovine brain

EA 162a-9601 G phosphatidylserine native, IgG 2/12/120 RU/ml 96 x 01 2.92 280.00bovine brain

EA 162a-9601 M phosphatidylserine native, IgM 2/12/120 RU/ml 96 x 01 2.92 280.00bovine brain

EA 162a-9601 P phosphatidylserine native, IgAGM 2/12/120 RU/ml 96 x 01 2.92 280.00bovine brain

EA 1622-9601 G AMA M2-3E native, pyruvate dehydrogenase IgG 2/20/200 RU/ml 96 x 01 2.92 280.00complex, porcine heart plus

recombinant M2 fusion antigen (BPO)

EA 1632-9601 A ß2-glycoprotein 1 native, IgA 2/20/200 RU/ml 96 x 01 2.92 280.00human serum

EA 1632-9601 G ß2-glycoprotein 1 native, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00human serum

EA 1632-9601 M ß2-glycoprotein 1 native, IgM 2/20/200 RU/ml 96 x 01 2.92 280.00human serum

EA 1632-9601 P ß2-glycoprotein 1 native, IgAGM 2/20/200 RU/ml 96 x 01 2.92 280.00human serum

EA 1641-9601 G ribosomal P-proteins native, P0/P1/P2 of the 60S ribosomal IgG 2/20/200 RU/ml 96 x 01 2.92 280.00subunit, bovine and rabbit thymus

EA 1661-9601 G Jo-1 native, histidyl-tRNA synthetase, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00calf thymus

EA 1814-9601 A IgA rheumatoid factor IgG, IgA 2/20/200 RU/ml 96 x 01 2.92 280.00(ab of class IgA against IgG) human

EA 1814-9601 G IgG rheumatoid factor IgG, IgG 2/20/200 RU/ml 96 x 01 2.92 280.00(ab of class IgG against IgG) goat

EA 1814-9601 M IgM rheumatoid factor IgG, IgM 2/20/200 RU/ml 96 x 01 2.92 280.00(ab of class IgM against IgG) human

EA 1818-9601 G circulating immune complexes native, IgG 2/20/200 RU/ml 96 x 01 3.75 360.00(CIC) human C1q

EA 1910-9601 A tissue transglutaminase recombinant, IgA 2/20/200 RU/ml 96 x 01 2.92 280.00(endomysium) expression with baculovirus vector

in insect cells

EA 1910-9601 G tissue transglutaminase recombinant, IgG semi-quantitative 96 x 01 2.92 280.00(endomysium) expression with baculovirus vector

in insect cells

EA 1910-9601 N * tissue transglutaminase recombinant, IgAG 2/20/200 RU/ml 96 x 01 2.92 280.00(endomysium) expression with baculovirus vector

in insect cells

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Price (€)

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Antibodies

against

Antigen and

Antigen Source

FormatOrder No. Price (€)

per Well

Radioimmunoassays (RIA) for the Determination of Autoantibodies (Test Systems)

Calibration

RA 1012-10001-1 thyroid peroxidase (TPO) native thyroid 0/8/40/200/1000/ 100 x 01 2.75 275.00coated tubes (CT) peroxidase, human 7500 U/ml

RA 1012-10001-2 thyroid peroxidase (TPO) native thyroid 12/40/120/400/ 100 x 01 2.75 275.00precipitation peroxidase, human 1200/4000 U/ml

RA 1012-10001-3 thyroid peroxidase (TPO) native thyroid 20/80/400/2000/ 100 x 01 2.30 230.00RA 1012-20001-3 magnetic separation peroxidase, human 8000 U/ml 200 x 01 2.00 400.00

RA 1013-10001-1 thyroglobulin (TG) native thyroglobulin, 0/20/50/200/1000/ 100 x 01 2.75 275.00coated tubes (CT) human 4000 U/ml

RA 1013-10001-2 thyroglobulin (TG) native thyroglobulin, 6/20/60/200/600/ 100 x 01 2.75 275.00precipitation human 2000 U/ml

RA 1013-10001-3 thyroglobulin (TG) native thyroglobulin, 20/80/250/1000/ 100 x 01 2.30 230.00magnetic separation human 4000 U/ml

RA 1015-10001-1 TSH receptor native TSH receptor, 0/1/2/8/40 IU/l 100 x 01 3.75 375.00coated tubes (CT) porcine

RA 1015-10001-2 TSH receptor native TSH receptor, 0/5/15/45/135/405 U/l 100 x 01 3.50 350.00polyethyleneglycol (PEG) separation porcine

RA 1022-5001 GAD recombinant 0/1/3/10/30/300 U/ml 50 x 01 5.60 280.00RA 1022-10001 precipitation glutamic acid decarboxylase 100 x 01 4.00 400.00

RA 1023-5001 IA2 recombinant 0/0.75/2/10/50 U/ml 50 x 01 5.60 280.00RA 1023-10001 precipitation tyrosine phosphatase 100 x 01 4.00 400.00

RA 1024-5001 insulin synthetic product, 0/0.5/1/10/50 U/ml 50 x 01 5.60 280.00RA 1024-10001 precipitation human 100 x 01 4.00 400.00

RA 1435-2501 acetylcholine receptor (ACHR) extract, 0/0.25/0.5/2/ 25 x 01 8.80 220.00RA 1435-10001 precipitation human 4/8 nmol/l 100 x 01 7.10 710.00

RA 1438-1201 * P/Q calcium channels (VGCC) extract, indirect 12 x 01 20.83 250.00precipitation leporine

RA 1571-10001 double-stranded DNA (dsDNA) plasmid DNA variable calibration 100 x 01 4.00 400.00precipitation

Price (€)per Kit

Antigen Analyte FormatOrder No. Price (€)per Well

RIA for Direct Detection of Autoantigens, Hormone Determination (Test Systems)

Calibration

RD 1013-10001 thyroglobulin (TG) native 0.3/1/4/20/100/ 100 x 01 3.10 310.00coated tubes (CT); IRMA thyroglobulin 250 ng/ml

RD 1016-10001 free triiodothyronin (FT3) triiodothyronin, 0/2/5/10/20/ 100 x 01 0.85 85.00coated tubes (CT) human 40 pmol/l

RD 1017-10001 free thyroxin (FT4) thyroxin, 0/6/12/25/50/ 100 x 01 0.85 85.00coated tubes (CT) human 100 pmol/l

RD 1018-10001 thyrotropin (TSH) thyrotropin, 0/0.06/0.15/0.6/2.5/ 100 x 01 1.05 105.00coated tubes (CT); IRMA human 15/50/100 µlU/ml

RD 1019-10001 calcitonin calcitonin, 6 standards, variable 100 x 01 2.90 290.00coated tubes (CT); IRMA human 0-2000 pg/ml

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Antigen and

Antigen Source

Ig Class FormatOrder No. Price (€)

per Well

Microplate ELISA for Infectious Serology (Test Systems)

Calibration

EI 2040-9601 G diphtheria toxoid inactivated IgG 0.01/0.1/1/2 IU/ml 96 x 01 2.92 280.00diphtheria toxin

EI 2060-9601 G tetanus toxoid inactivated IgG 0,01/0,1/1/4/10 IU/ml 96 x 01 2.92 280.00tetanus toxin

EI 2080-9601 A Helicobacter pylori bacterial lysate, IgA semi-quantitative 96 x 01 2.08 200.00strain “ATCC 43504”

EI 2080-9601 G Helicobacter pylori bacterial lysate, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00strain “ATCC 43504”

EI 2081-9601 A Helicobacter pylori recombinant CagA, IgA semi-quantitative 96 x 01 2.08 200.00(CagA) expression in E. coli

EI 2081-9601 G Helicobacter pylori recombinant CagA, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(CagA) expression in E. coli

EI 2111-9601 G Treponema pallidum 15 kDa, 17 kDa, 47 kDa, IgG 2/20/200 RU/ml 96 x 01 2.08 200.0042 kDa (TmpA)

EI 2111-9601 M Treponema pallidum 15 kDa, 17 kDa, 47 kDa, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent 42 kDa (TmpA)

EI 2111-9601 O Treponema pallidum 15 kDa, 17 kDa, 47 kDa, IgGM 2/20/200 RU/ml 96 x 01 2.08 200.00screen ELISA 42 kDa (TmpA)

EI 2111-9601-L G Treponema pallidum 15 kDa, 17 kDa, 47 kDa, IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF 42 kDa (TmpA)

EI 2132-9601 G Borrelia whole antigen, SDS extracts of IgG 2/20/200 RU/ml 96 x 01 2.08 200.00Borrelia burgdorferi sensu stricto,Borrelia garinii and Borrelia afzelii

EI 2132-9601 M Borrelia whole antigen, SDS extracts of IgM 2/20/200 RU/ml 96 x 01 2.29 220.00incl. IgG/RF absorbent Borrelia burgdorferi sensu stricto,

Borrelia garinii and Borrelia afzelii

EI 2132-9601-1 G Borrelia burgdorferi recombinant VlsE from IgG 2/20/200 RU/ml 96 x 01 3.13 300.00VlsE Borrelia burgdorferi sensu stricto

EI 2132-9601-2 G Borrelia whole antigen, SDS extracts of IgG 2/20/200 RU/ml 96 x 01 2.40 230.00PLUS VlsE Borrelia burgdorferi sensu stricto,

Borrelia garinii and Borrelia afzeliiPLUS recombinant VlsE from

Borrelia burgdorferi sensu stricto

EI 2132-9601-L G Borrelia PLUS VlsE whole antigen, SDS extracts of IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF Borrelia burgdorferi sensu stricto,

Borrelia garinii and Borrelia afzeliiPLUS recombinant VlsE from

Borrelia burgdorferi sensu stricto

EI 2132-9601-L M Borrelia whole antigen, SDS extracts of IgM 5/25/50/100 U 96 x 01 2.81 270.00antibody determination in CSF Borrelia burgdorferi sensu stricto,

Borrelia garinii and Borrelia afzelii

EI 2150-9601 A Legionella pneumophila native, lipopolysaccharide (LPS) IgA semi-quantitative 96 x 01 2.08 200.00of the serotypes 1-7

EI 2150-9601 G Legionella pneumophila native, lipopolysaccharide (LPS) IgG 2/20/200 RU/ml 96 x 01 2.08 200.00of the serotypes 1-7

EI 2150-9601 M Legionella pneumophila native, lipopolysaccharide (LPS) IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent of the serotypes 1-7

EI 2173-9601 A Yersinia enterocolitica recombinant Yop D IgA semi-quantitative 96 x 01 2.08 200.00Detection of antibodies against virulence of Yersinia

factors of the Yersinia enterocolitica pathogen enterocoliticain human serum (for diagnosing various

forms of arthritis)

EI 2173-9601 G Yersinia enterocolitica isolated virulence factors IgG 2/20/200 RU/ml 96 x 01 2.08 200.00Detection of antibodies against virulence (release proteins, Yop)

factors of the Yersinia enterocolitica pathogen of Yersiniain human serum (for diagnosing various enterocolitica

forms of arthritis)

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Antibodies

against

Antigen and

Antigen Source

Ig Class FormatOrder No. Price (€)

per Well

Microplate ELISA for Infectious Serology (Test Systems)

Calibration

EI 2189-9601 A Brucella abortus bacterial lysate, IgA semi-quantitative 96 x 01 2.08 200.00Brucella abortus strain “W99”

EI 2189-9601 G Brucella abortus bacterial lysate, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00Brucella abortus strain “W99”

EI 2189-9601 M Brucella abortus bacterial lysate, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent Brucella abortus strain “W99”

EI 2191-9601 A Chlamydia trachomatis native MOMP antigen, IgA semi-quantitative 96 x 01 2.08 200.00infected BGM cells, serotype K

EI 2191-9601 G Chlamydia trachomatis native MOMP antigen, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00infected BGM cells, serotype K

EI 2191-9601 M Chlamydia trachomatis native MOMP antigen, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent infected BGM cells, serotype K

EI 2192-9601 A Chlamydia pneumoniae cell lysate of HL cells, IgA semi-quantitative 96 x 01 2.08 200.00strain “CDC/CWL-029”

EI 2192-9601 G Chlamydia pneumoniae cell lysate of HL cells, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00strain “CDC/CWL-029”

EI 2192-9601 M Chlamydia pneumoniae cell lysate of HL cells, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “CDC/CWL-029”

EI 2202-9601 A Mycoplasma pneumoniae detergent extract of IgA semi-quantitative 96 x 01 2.08 200.00strain “Mac ATCC 15531”

EI 2202-9601 G Mycoplasma pneumoniae detergent extract of IgG 2/20/200 RU/ml 96 x 01 2.08 200.00strain “Mac ATCC 15531”

EI 2202-9601 M Mycoplasma pneumoniae detergent extract of IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “Mac ATCC 15531”

EI 2320-9601 G Echinococcus granulosus cyst extract IgG 2/20/200 RU/ml 96 x 01 2.08 200.00

EI 2410-9601 A * Toxoplasma gondii whole antigen, IgA semi-quantitative 96 x 01 2.08 200.00strain “Deelen”

EI 2410-9601 G Toxoplasma gondii whole antigen, IgG 1/10/200 IU/ml 96 x 01 2.08 200.00strain “Deelen”

EI 2410-9601 M Toxoplasma gondii whole antigen, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “Deelen”

EI 2410-9601-1 G Toxoplasma gondii whole antigen, IgG without calibration 96 x 01 2.60 250.00avidity determination strain “Deelen”

EI 2410-9601-L G Toxoplasma gondii whole antigen, IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF strain “Deelen”

EI 2531-9601-1 A Herpes simplex virus HSV-1: strain “Mac Intyre” (ATCC VR-539) IgA semi-quantitative 96 x 01 2.08 200.00(HSV-1/2 Pool) HSV-2: strain “MS” (ATCC VR-540)

EI 2531-9601-1 G Herpes simplex virus HSV-1: strain “Mac Intyre” (ATCC VR-539) IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(HSV-1/2 Pool) HSV-2: strain “MS” (ATCC VR-540)

EI 2531-9601-1 L G Herpes simplex virus HSV-1: strain “Mac Intyre” (ATCC VR-539) IgG 1/8/40/100 RU/ml 96 x 01 2.60 250.00(HSV-1/2 Pool) HSV-2: strain “MS” (ATCC VR-540)

antibody determination in CSF

EI 2531-9601-1 M Herpes simplex virus HSV-1: strain “Mac Intyre” (ATCC VR-539) IgM semi-quantitative 96 x 01 2.29 220.00(HSV-1/2 Pool) HSV-2: strain “MS” (ATCC VR-540)

incl. IgG/RF absorbent

EI 2531-9601-2 G Herpes simplex virus 1 native, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(HSV-1) glycoprotein C1

EI 2531-9601-2 M Herpes simplex virus 1 (HSV-1) native, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent glycoprotein C1

EI 2531-9601-L G Herpes simplex virus 1 (HSV-1) native, IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF glycoprotein C1

EI 2532-9601-2 G Herpes simplex virus 2 native, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(HSV-2) glycoprotein G2

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Ig Class FormatOrder No. Price (€)

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Microplate ELISA for Infectious Serology (Test Systems)

Calibration

EI 2532-9601-2 M Herpes simplex virus 2 (HSV-2) native, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent glycoprotein G2

EI 2532-9601-L G Herpes simplex virus 2 (HSV-2) native, IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF glycoprotein G2

EI 2570-9601 G Cytomegalovirus cell lysate of MRC-5 cells, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(CMV) strain “AD169”

EI 2570-9601 M Cytomegalovirus (CMV) cell lysate of MRC-5 cells, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “AD169”

EI 2570-9601-1 G Cytomegalovirus (CMV) cell lysate of MRC-5 cells, IgG without calibration 96 x 01 2.60 250.00avidity determination strain “AD169”

EI 2570-9601-L G Cytomegalovirus (CMV) cell lysate of MRC-5 cells, IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF strain “AD169”

EI 2590-9601 G Rubella virus cell lysate of Vero cells, IgG 1/10/200 IU/ml 96 x 01 2.08 200.00strain “HPV-77”

EI 2590-9601 M Rubella virus cell lysate of Vero cells, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “HPV-77”

EI 2590-9601-1 G Rubella virus cell lysate of Vero cells, IgG without calibration 96 x 01 2.60 250.00avidity determination strain “HPV-77”

EI 2590-9601-L G Rubella virus cell lysate of Vero cells, IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF strain “HPV-77”

EI 2601-9601 G SARS coronavirus cell lysate of SARS-CoV IgG semi-quantitative 96 x 01 2.50 240.00infected cells

EI 2610-9601 G Measles virus cell lysate of Vero cells, IgG 50/250/5000 mIU/ml 96 x 01 2.08 200.00strain “Edmonston”

(ATCC VR-24)

EI 2610-9601 M Measles virus cell lysate of Vero cells, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “Edmonston”

(ATCC VR-24)

EI 2610-9601-L G Measles virus cell lysate of Vero cells, IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF strain “Edmonston”

(ATCC VR-24)

EI 2630-9601 G Mumps virus cell lysate of Vero cells, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00strain “Enders”(ATCC VR-106)

EI 2630-9601 M Mumps virus cell lysate of Vero cells, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “Enders”

(ATCC VR-106)

EI 2630-9601-L G Mumps virus cell lysate of Vero cells, IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF strain “Enders”

(ATCC VR-106)

EI 2650-9601 A Varicella zoster virus cell lysate of a human fibroblast IgA semi-quantitative 96 x 01 2.08 200.00(VZV) cell line, VZV wild strain

EI 2650-9601 G Varicella zoster virus cell lysate of a human fibroblast IgG 50/250/5000 mIU/ml 96 x 01 2.08 200.00(VZV) cell line, VZV wild strain

EI 2650-9601 M Varicella zoster virus (VZV) cell lysate of MRC-2 cells, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “VZ-10”

EI 2650-9601-1 G Varicella zoster virus (VZV) cell lysate of a human fibroblast IgG without calibration 96 x 01 2.60 250.00avidity determination cell line, VZV wild strain

EI 2650-9601-L G Varicella zoster virus (VZV) cell lysate of a human fibroblast IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF cell line, VZV wild strain

EI 2661-9601 G TBE virus strain IgG 2/20/200 RU/ml 96 x 01 2.08 200.00“K23”

EI 2661-9601 M TBE virus strain IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent “K23”

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EI 2661-9601-L G TBE virus strain IgG 5/25/50/100 U 96 x 01 2.60 250.00antibody determination in CSF “K23”

EI 2662-9601 G West Nile Virus cell lysate of West Nile Virus IgG semi-quantitative 96 x 01 2.08 200.00infected cells

EI 2662-9601 M West Nile Virus cell lysate of West Nile Virus IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent infected cells

EI 2662-9601-1 G West Nile Virus cell lysate of West Nile Virus IgG without calibration 96 x 01 2.60 250.00avidity determination infected cells

EI 266b-9601 G Dengue virus highly purified preparation from IgG 2/20/200 RU/ml 96 x 01 2.08 200.00Dengue virus particles (type 2)

EI 266b-9601 M Dengue virus highly purified preparation from IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent Dengue virus particles (type 2)

EI 2670-9601 A Respiratory syncytial virus cell lysate of Vero cells, IgA semi-quantitative 96 x 01 2.08 200.00(RSV) strain “RuS”

EI 2670-9601 G Respiratory syncytial virus cell lysate of Vero cells, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(RSV) strain “RuS”

EI 2670-9601 M Respiratory syncytial virus (RSV) cell lysate of Vero cells, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “RuS”

EI 2680-9601 A Adenovirus cell lysate of MRC-5 cells, IgA semi-quantitative 96 x 01 2.08 200.00strain “Adenoid 6”

EI 2680-9601 G Adenovirus cell lysate of MRC-5 cells, IgG 2/20/200 RU/ml 96 x 01 2.08 200.00strain “Adenoid 6”

EI 2680-9601 M Adenovirus cell lysate of MRC-5 cells, IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent strain “Adenoid 6”

EI 2691-9601 A Influenza virus type A strain “Texas” IgA semi-quantitative 96 x 01 2.08 200.00and strain “Singapore”

EI 2691-9601 G Influenza virus type A strain “Texas” IgG 2/20/200 RU/ml 96 x 01 2.08 200.00and strain “Singapore”

EI 2691-9601 M Influenza virus type A strain “Texas” IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent and strain “Singapore”

EI 2691-9601-1 A Influenza virus see individual ELISA IgA semi-quantitative 96 x 01 2.08 200.00types A and B (Pool)

EI 2691-9601-1 G Influenza virus see individual ELISA IgG 2/20/200 RU/ml 96 x 01 2.08 200.00types A and B (Pool)

EI 2692-9601 A Influenza virus type B strain IgA semi-quantitative 96 x 01 2.08 200.00“Hong Kong 5/72”

EI 2692-9601 G Influenza virus type B strain IgG 2/20/200 RU/ml 96 x 01 2.08 200.00“Hong Kong 5/72”

EI 2692-9601 M Influenza virus type B strain IgM semi-quantitative 96 x 01 2.29 220.00incl. IgG/RF absorbent “Hong Kong 5/72”

EI 2721-9601-1 A Parainfluenza virus cell lysate of Vero cells, strains IgA semi-quantitative 96 x 01 2.08 200.00types 1 - 4 (Pool) “VP1”, “Greer”, “C-234” and “M25”

EI 2721-9601-1 G Parainfluenza virus cell lysate of Vero cells, strains IgG 2/20/200 RU/ml 96 x 01 2.08 200.00types 1 - 4 (Pool) “VP1”, “Greer”, “C-234” and “M25”

EI 2721-9601-1 M Parainfluenza virus types 1 - 4 cell lysate of Vero cells, strains IgM semi-quantitative 96 x 01 2.29 220.00(Pool) incl. IgG/RF absorbent “VP1”, “Greer”, “C-234” and “M25”

EI 2791-9601 A Epstein-Barr virus capsid antigen native, mixture of several IgA semi-quantitative 96 x 01 2.08 200.00(EBV-CA) viral capsid antigens

EI 2791-9601 G Epstein-Barr virus capsid antigen native, mixture of several IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(EBV-CA) viral capsid antigens

EI 2791-9601 M Epstein-Barr virus capsid antigen native, gp125 of IgM semi-quantitative 96 x 01 2.29 220.00(EBV-CA) incl. IgG/RF absorbent EBV infected P3HR1 cells

EI 2791-9601-1 G Epstein-Barr virus capsid antigen native, mixture of several IgG without calibration 96 x 01 2.60 250.00(EBV-CA) avidity determination viral capsid antigens

Price (€)

per Kit

Antibodies

against

Antigen and

Antigen Source

Ig Class FormatOrder No. Price (€)

per Well

Microplate ELISA for Infectious Serology (Test Systems)

Calibration

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Antigen andAntigen Source

Ig Class FormatOrder No. Price (€)per Well

Microplate ELISA for the Determination of Antibodies against Other Antigens (Test Systems)

Calibration

EV 2841-9601 A Saccharomyces cerevisiae mannan of IgA 2/20/200 RU/ml 96 x 01 2.92 280.00S. cerevisiae

EV 2841-9601 G Saccharomyces cerevisiae mannan of IgG 2/20/200 RU/ml 96 x 01 2.92 280.00S. cerevisiae

EV 3011-9601 A gliadin gliadin-analogue fusion peptide IgA 2/25/200 RU/ml 96 x 01 3,33 320,00 (GAF-3X) (GAF-3X)

EV 3011-9601 G gliadin gliadin-analogue fusion peptide IgG 2/25/200 RU/ml 96 x 01 3,33 320,00 (GAF-3X) (GAF-3X)

EV 3840-9601 E total IgE anti-human IgE IgE 0/10/100/500 IU/ml 96 x 01 2.92 280.00(sheep)

EI 2791-9601-L G Epstein-Barr virus capsid antigen native, mixture of several IgG 5/25/50/100 U 96 x 01 2.60 250.00(EBV-CA) antibody determination in CSF viral capsid antigens

EI 2793-9601 G Epstein-Barr virus nuclear antigen recombinant, expression IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(EBNA-1) in insect cells

EI 2795-9601 A Epstein-Barr virus early antigen recombinant, EBV-EA-D (diffuse), IgA semi-quantitative 96 x 01 2.08 200.00(EBV-EA) expression in E. coli

EI 2795-9601 G Epstein-Barr virus early antigen recombinant, EBV-EA-D (diffuse), IgG 2/20/200 RU/ml 96 x 01 2.08 200.00(EBV-EA) expression in E. coli

EI 2795-9601 M Epstein-Barr virus early antigen recombinant, EBV-EA-D (diffuse), IgM semi-quantitative 96 x 01 2.29 220.00(EBV-EA) incl. IgG/RF absorbent expression in E. coli

Price (€)

per Kit

Antibodies

against

Antigen and

Antigen Source

Ig Class FormatOrder No. Price (€)

per Well

Microplate ELISA for Infectious Serology (Test Systems)

Calibration

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ZP 3000-0100 22000 conjugate pack for 100 analyses 200.00

ZP 3001-0060 22001 reference set for 5 reference curves in double determination 100.00

ZP 3002-0511 22002 washing solution (concentrate) for 5 x 500 ml 20.00

ZP 3003-0511 22003 substrate buffer 5 x 13.5 ml, ready for use 25.00(incl. 5 substrate tablets)

ZP 3004-0511 22004 stop solution 5 x 11 ml, ready for use 20.00

ZP 3008-0125 22008 positive control serum 2.5 ml, ready for use 30.00(G5)

ZP 3009-0125 22009 negative control serum 2.5 ml, ready for use 20.00(G5)

ZP 3020-9601 microplate 96 microplate wells 0.59(can only be ordered in combination

with further reagents)

Price (€)Reagent FormatOrder No.

Allercoat™ 6 System: Basic Reagents and Accessories

PreviousOrder No.

Price (€)per Package

Antibodiesof Class IgE against

Substrate FormatOrder No. Price (€)per Ring

Allercoat™ 6 System: Allergen Rings (Pharmaceutical Drugs)

PreviousOrder No.

EP C000-0110 22414 HSA paper rings with allergen 01 x 10 3.20 32.00Human serum albumin

EP C001-0110 22250 C1 paper rings with allergen 01 x 10 3.20 32.00Penicilloyl G - HSA

EP C002-0110 22251 C2 paper rings with allergen 01 x 10 3.20 32.00Penicilloyl V - HSA

EP C003-0110 22252 C3 paper rings with allergen 01 x 10 3.20 32.00A.C.T.H.

EP C004-0110 22253 C4 paper rings with allergen 01 x 10 3.20 32.00Chymopapain (Discase)

EP C005-0110 22254 C5 paper rings with allergen 01 x 10 3.20 32.00Chymopapain

EP C006-0110 22255 C6 paper rings with allergen 01 x 10 3.20 32.00Cephalosporin - HSA

EP C007-0110 22256 C7 paper rings with allergen 01 x 10 3.20 32.00Baktrim - HSA

EP C025-0110 22570 C25 paper rings with allergen 01 x 10 3.20 32.00Allopurinol - HSA

EP C049-0110 22575 C49 paper rings with allergen 01 x 10 3.20 32.00Propicillin - HSA

EP C053-0110 22552 C53 paper rings with allergen 01 x 10 3.20 32.00Alcuronium - HSA

EP C054-0110 22576 C54 paper rings with allergen 01 x 10 3.20 32.00Cefalotin - HSA

EP C060-0110 22577 C60 paper rings with allergen 01 x 10 3.20 32.00Gentamycin - HSA

EP C061-0110 22578 C61 paper rings with allergen 01 x 10 3.20 32.00Erythromycin - HSA

EP C062-0110 22579 C62 paper rings with allergen 01 x 10 3.20 32.00Doxycyclin - HSA

EP C064-0110 22580 C64 paper rings with allergen 01 x 10 3.20 32.00Piperacillin - HSA

EP C065-0110 22581 C65 paper rings with allergen 01 x 10 3.20 32.00Phenylbutazone - HSA

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EP C067-0110 22582 C67 paper rings with allergen 01 x 10 3.20 32.00Cloxacillin - HSA

EP C068-0110 22583 C68 paper rings with allergen 01 x 10 3.20 32.00Articain - HSA

EP C070-0110 22268 C70 paper rings with allergen 01 x 10 3.20 32.00Porcine insulin

EP C071-0110 22269 C71 paper rings with allergen 01 x 10 3.20 32.00Bovine insulin

EP C073-0110 22270 C73 paper rings with allergen 01 x 10 3.20 32.00Human insulin

EP C075-0110 22584 C75 paper rings with allergen 01 x 10 3.20 32.00Bromelain - HSA

EP C077-0110 22585 C77 paper rings with allergen 01 x 10 3.20 32.00Piroxicam - HSA

EP C078-0110 22586 C78 paper rings with allergen 01 x 10 3.20 32.00Ibuprofen - HSA

EP C079-0110 22587 C79 paper rings with allergen 01 x 10 3.20 32.00Diclofenac - HSA

EP C080-0110 22588 C80 paper rings with allergen 01 x 10 3.20 32.00Tetanus

EP C081-0110 22589 C81 paper rings with allergen 01 x 10 3.20 32.00Theophylline/Aminophylline - HSA

EP C082-0110 22590 C82 paper rings with allergen 01 x 10 3.20 32.00Lidocaine - HSA

EP C083-0110 22553 C83 paper rings with allergen 01 x 10 3.20 32.00Novocaine - HSA

EP C086-0110 22591 C86 paper rings with allergen 01 x 10 3.20 32.00Benzocaine - HSA

EP C088-0110 22554 C88 paper rings with allergen 01 x 10 3.20 32.00Mepivacaine - HSA

EP C089-0110 22592 C89 paper rings with allergen 01 x 10 3.20 32.00Bupivacaine - HSA

EP C090-0110 22593 C90 paper rings with allergen 01 x 10 3.20 32.00Propyphenazon - HSA

EP C091-0110 22594 C91 paper rings with allergen 01 x 10 3.20 32.00Metamizol - HSA

EP C093-0110 22595 C93 paper rings with allergen 01 x 10 3.20 32.00Indomethacin - HSA

EP C094-0110 22555 C94 paper rings with allergen 01 x 10 3.20 32.00Tobramycin - HSA

EP C095-0110 22556 C95 paper rings with allergen 01 x 10 3.20 32.00Neomycin - HSA

EP C096-0110 22596 C96 paper rings with allergen 01 x 10 3.20 32.00Ambroxol - HSA

EP C097-0110 22597 C97 paper rings with allergen 01 x 10 3.20 32.00Bromhexine - HSA

EP C098-0110 22598 C98 paper rings with allergen 01 x 10 3.20 32.00Codeine - HSA

EP C099-0110 22599 C99 paper rings with allergen 01 x 10 3.20 32.00L-Tyroxin - HSA

EP C100-0110 22559 C100 paper rings with allergen 01 x 10 3.20 32.00Prilocain - HSA

EP C101-0110 22560 C101 paper rings with allergen 01 x 10 3.20 32.00Phenobarbital - HSA

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Pharmaceutical Drugs)

PreviousOrder No.

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EP C102-0110 22549 C102 paper rings with allergen 01 x 10 3.20 32.00Thiopental - HSA

EP C103-0110 22550 C103 paper rings with allergen 01 x 10 3.20 32.00Isoprenaline - HSA

EP C104-0110 22561 C104 paper rings with allergen 01 x 10 3.20 32.00Clindamycin - HSA

EP C106-0110 22562 C106 paper rings with allergen 01 x 10 3.20 32.00Vitamin B1 - HSA

EP C107-0110 22563 C107 paper rings with allergen 01 x 10 3.20 32.00Captopril - HSA

EP C108-0110 22551 C108 paper rings with allergen 01 x 10 3.20 32.00Ciprofloxacin - HSA

EP C109-0110 22564 C109 paper rings with allergen 01 x 10 3.20 32.00Vitamin B6 - HSA

EP C110-0110 22566 C110 paper rings with allergen 01 x 10 3.20 32.00Naproxen - HSA

EP C111-0110 22567 C111 paper rings with allergen 01 x 10 3.20 32.00Phenacetin - HSA

EP C112-0110 22568 C112 paper rings with allergen 01 x 10 3.20 32.00Diphteria toxin

EP C200-0110 22257 C200 paper rings with allergen 01 x 10 3.20 32.00Paracetamol - HSA

EP C201-0110 22258 C201 paper rings with allergen 01 x 10 3.20 32.00Acetylsalicylic acid - HSA

EP C203-0110 22259 C203 paper rings with allergen 01 x 10 3.20 32.00Ampicillin - HSA

EP C204-0110 22260 C204 paper rings with allergen 01 x 10 3.20 32.00Amoxicillin - HSA

EP C205-0110 22261 C205 paper rings with allergen 01 x 10 3.20 32.00Tetracycline - HSA

EP C206-0110 22262 C206 paper rings with allergen 01 x 10 3.20 32.00Streptomycin - HSA

EP C207-0110 22263 C207 paper rings with allergen 01 x 10 3.20 32.00Trimethoprim - HSA

EP C208-0110 22264 C208 paper rings with allergen 01 x 10 3.20 32.00Sulfomethoxazol - HSA

EP C209-0110 22265 C209 paper rings with allergen 01 x 10 3.20 32.00Pyrazolon - HSA

EP C210-0110 22266 C210 paper rings with allergen 01 x 10 3.20 32.00Muscle Relax. - HSA

EP C223-0110 22887 C223 paper rings with allergen 01 x 10 3.20 32.00Benzodiazepine - HSA

EP C300-0110 22267 C300 paper rings with allergen 01 x 10 3.20 32.00Procaine - HSA

EP C320-0110 22572 C320 paper rings with allergen 01 x 10 3.20 32.00Nifurantin - HSA

EP C379-0110 22888 C379 paper rings with allergen 01 x 10 3.20 32.00Butyrophenone/Haloperidol - HSA

EP C424-0110 22573 C424 paper rings with allergen 01 x 10 3.20 32.00Prednisolon - HSA

EP C430-0110 22574 C430 paper rings with allergen 01 x 10 3.20 32.00Pyrimethamine - HSA

EP C431-0110 22565 C431 paper rings with allergen 01 x 10 3.20 32.00Ascorbic acid - HSA

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Pharmaceutical Drugs)

PreviousOrder No.

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EP D001-0125 22050 D1 paper rings with allergen 01 x 25 3.20 80.00Dermatophagoides pteronyssinus

EP D002-0125 22051 D2 paper rings with allergen 01 x 25 3.20 80.00Dermatophagoides farinae

EP D004-0110 22600 D4 paper rings with allergen 01 x 10 3.20 32.00Dermatophagoides microceras

EP D070-0110 22271 D70 paper rings with allergen 01 x 10 3.20 32.00Acarus siro (storage mite)

EP D071-0110 22272 D71 paper rings with allergen 01 x 10 3.20 32.00Glycyphagus destructor

EP D072-0110 22273 D72 paper rings with allergen 01 x 10 3.20 32.00Tyrophagus putrescentiae

EP D073-0110 22274 D73 paper rings with allergen 01 x 10 3.20 32.00Glycyphagus domesticus

EP D074-0110 22275 D74 paper rings with allergen 01 x 10 3.20 32.00Euroglyphus maynei

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Mites)

PreviousOrder No.

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Animal Allergens)

PreviousOrder No.

EP E001-0125 22052 E1 paper rings with allergen 01 x 25 3.20 80.00Cat epithelium

EP E002-0125 22053 E2 paper rings with allergen 01 x 25 3.20 80.00Dog hair + epithelium

EP E003-0125 22054 E3 paper rings with allergen 01 x 25 3.20 80.00Horse epithelium

EP E004-0110 22276 E4 paper rings with allergen 01 x 10 3.20 32.00Cow epithelium

EP E005-0125 22055 E5 paper rings with allergen 01 x 25 3.20 80.00Dog squames

EP E006-0125 22056 E6 paper rings with allergen 01 x 25 3.20 80.00Guinea pig epithelium

EP E007-0110 22277 E7 paper rings with allergen 01 x 10 3.20 32.00Pigeon droppings

EP E008-0110 22557 E8 paper rings with allergen 01 x 10 3.20 32.00Mink fur and epithelium

EP E011-0110 22722 E11 paper rings with allergen 01 x 10 3.20 32.00Pigeon feathers

EP E012-0110 22725 E12 paper rings with allergen 01 x 10 3.20 32.00Pigeon protein

EP E013-0110 22726 E13 paper rings with allergen 01 x 10 3.20 32.00Pigeon serum

EP E014-0110 22603 E14 paper rings with allergen 01 x 10 3.20 32.00Canary serum

EP E015-0110 22727 E15 paper rings with allergen 01 x 10 3.20 32.00Chicken serum

EP E016-0110 22604 E16 paper rings with allergen 01 x 10 3.20 32.00Parrot serum

EP E017-0110 22728 E17 paper rings with allergen 01 x 10 3.20 32.00Camel hair (native) + epithelium

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EP E018-0110 22605 E18 paper rings with allergen 01 x 10 3.20 32.00Canary droppings

EP E019-0110 22729 E19 paper rings with allergen 01 x 10 3.20 32.00Goose droppings

EP E020-0110 22606 E20 paper rings with allergen 01 x 10 3.20 32.00Chicken droppings

EP E030-0110 22730 E30 paper rings with allergen 01 x 10 3.20 32.00Human hair

EP E050-0110 22731 E50 paper rings with allergen 01 x 10 3.20 32.00Finch feathers + droppings

EP E052-0110 22607 E52 paper rings with allergen 01 x 10 3.20 32.00Rabbit/hare epithelium

EP E070-0125 22057 E70 paper rings with allergen 01 x 25 3.20 80.00Goose feathers

EP E071-0110 22280 E71 paper rings with allergen 01 x 10 3.20 32.00Mouse epithelium

EP E072-0110 22281 E72 paper rings with allergen 01 x 10 3.20 32.00Mouse urine proteins

EP E073-0110 22282 E73 paper rings with allergen 01 x 10 3.20 32.00Rat epithelium

EP E074-0110 22283 E74 paper rings with allergen 01 x 10 3.20 32.00Rat urine proteins

EP E075-0110 22284 E75 paper rings with allergen 01 x 10 3.20 32.00Rat serum proteins

EP E076-0110 22285 E76 paper rings with allergen 01 x 10 3.20 32.00Mouse serum proteins

EP E077-0110 22286 E77 paper rings with allergen 01 x 10 3.20 32.00Budgerigar droppings

EP E078-0125 22058 E78 paper rings with allergen 01 x 25 3.20 80.00Budgerigar feathers

EP E079-0110 22287 E79 paper rings with allergen 01 x 10 3.20 32.00Budgerigar serum proteins

EP E080-0110 22288 E80 paper rings with allergen 01 x 10 3.20 32.00Goat epithelium

EP E081-0110 22289 E81 paper rings with allergen 01 x 10 3.20 32.00Sheep epithelium

EP E082-0110 22290 E82 paper rings with allergen 01 x 10 3.20 32.00Rabbit epithelium

EP E083-0110 22291 E83 paper rings with allergen 01 x 10 3.20 32.00Pig epithelium

EP E084-0110 22292 E84 paper rings with allergen 01 x 10 3.20 32.00Hamster epithelium

EP E085-0110 22293 E85 paper rings with allergen 01 x 10 3.20 32.00Chicken feathers

EP E086-0125 22059 E86 paper rings with allergen 01 x 25 3.20 80.00Duck feathers

EP E089-0110 22732 E89 paper rings with allergen 01 x 10 3.20 32.00Mouse droppings

EP E090-0110 22294 E90 paper rings with allergen 01 x 10 3.20 32.00Canary feathers

EP E091-0110 22295 E91 paper rings with allergen 01 x 10 3.20 32.00Parrot feathers

EP E093-0110 22608 E93 paper rings with allergen 01 x 10 3.20 32.00Love bird serum

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Animal Allergens)

PreviousOrder No.

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EP E094-0110 22737 E94 paper rings with allergen 01 x 10 3.20 32.00Ring-necked parakeet droppings

EP E096-0110 22610 E96 paper rings with allergen 01 x 10 3.20 32.00Love bird droppings

EP E097-0110 22609 E97 paper rings with allergen 01 x 10 3.20 32.00Parrot droppings

EP E098-0110 22738 E98 paper rings with allergen 01 x 10 3.20 32.00Chinchilla epithelium + hair

EP E099-0110 22739 E99 paper rings with allergen 01 x 10 3.20 32.00Rabbit droppings

EP E100-0110 22558 E100 paper rings with allergen 01 x 10 3.20 32.00Duck droppings

EP E103-0110 22721 E103 paper rings with allergen 01 x 10 3.20 32.00Wild-pig epithelium + hair

EP E104-0110 22601 E104 paper rings with allergen 01 x 10 3.20 32.00Horse hair

EP E110-0110 22723 E110 paper rings with allergen 01 x 10 3.20 32.00Ring-necked parakeet feathers

EP E111-0110 22602 E111 paper rings with allergen 01 x 10 3.20 32.00Goose down

EP E113-0110 22724 E113 paper rings with allergen 01 x 10 3.20 32.00Zebra finch feathers

EP E120-0110 22733 E120 paper rings with allergen 01 x 10 3.20 32.00Rat Droppings

EP E121-0110 22736 E121 paper rings with allergen 01 x 10 3.20 32.00Turkey feathers

EP E204-0110 22278 E204 paper rings with allergen 01 x 10 3.20 32.00Bovine serum albumin

EP E205-0110 22279 E205 paper rings with allergen 01 x 10 3.20 32.00Horse serum albumin

EP ES11-0125 22150 ES11 paper rings with 01 x 25 3.20 80.00Animals allergen mixture

(E1, E3, E4, E5)

EP ES170-0110 22950 ES170 paper rings with 01 x 10 3.20 32.00Rodents allergen mixture

(E6, E71, E73, E82, E84)

EP ES171-0125 22151 ES171 paper rings with 01 x 25 3.20 80.00Feathers allergen mixture

(E70, E85, E86)

EP ES172-0110 22963 ES172 paper rings with 01 x 10 3.20 32.00Cage birds allergen mixture

(E78, E90, E91, E110, E 113)

EP ES173-0125 22171 ES173 paper rings with 01 x 25 3.20 80.00Bed feathers allergen mixture

(E86, E70)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Animal Allergens)

PreviousOrder No.

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Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

EP F001-0125 22060 F1 paper rings with allergen 01 x 25 3.20 80.00Hen’s egg white

EP F002-0125 22061 F2 paper rings with allergen 01 x 25 3.20 80.00Cows milk protein

EP F003-0125 22062 F3 paper rings with allergen 01 x 25 3.20 80.00Codfish

EP F004-0125 22063 F4 paper rings with allergen 01 x 25 3.20 80.00Wheat flour

EP F005-0125 22064 F5 paper rings with allergen 01 x 25 3.20 80.00Rye flour

EP F006-0110 22296 F6 paper rings with allergen 01 x 10 3.20 32.00Barley flour

EP F007-0110 22297 F7 paper rings with allergen 01 x 10 3.20 32.00Oat flour

EP F008-0110 22300 F8 paper rings with allergen 01 x 10 3.20 32.00Corn flour (Maize flour)

EP F009-0110 22301 F9 paper rings with allergen 01 x 10 3.20 32.00Rice

EP F010-0110 22302 F10 paper rings with allergen 01 x 10 3.20 32.00Sesame seeds, ground

EP F011-0110 22311 F11 paper rings with allergen 01 x 10 3.20 32.00Buckwheat flour

EP F012-0110 22314 F12 paper rings with allergen 01 x 10 3.20 32.00Pea

EP F013-0125 22066 F13 paper rings with allergen 01 x 25 3.20 80.00Peanuts

EP F014-0125 22067 F14 paper rings with allergen 01 x 25 3.20 80.00Soybean

EP F015-0110 22315 F15 paper rings with allergen 01 x 10 3.20 32.00White bean

EP F016-0110 22316 F16 paper rings with allergen 01 x 10 3.20 32.00Walnut

EP F017-0125 22068 F17 paper rings with allergen 01 x 25 3.20 80.00Hazelnut

EP F018-0110 22317 F18 paper rings with allergen 01 x 10 3.20 32.00Brazil nut

EP F019-0110 22318 F19 paper rings with allergen 01 x 10 3.20 32.00Sweet chestnut

EP F020-0110 22319 F20 paper rings with allergen 01 x 10 3.20 32.00Almond

EP F021-0110 22321 F21 paper rings with allergen 01 x 10 3.20 32.00Herring

EP F022-0110 22323 F22 paper rings with allergen 01 x 10 3.20 32.00Trout

EP F023-0110 22324 F23 paper rings with allergen 01 x 10 3.20 32.00Shrimp

EP F024-0110 22330 F24 paper rings with allergen 01 x 10 3.20 32.00Prawn, North Sea

EP F025-0125 22069 F25 paper rings with allergen 01 x 25 3.20 80.00Tomato

EP F026-0125 22070 F26 paper rings with allergen 01 x 25 3.20 80.00Pork, raw

EP F027-0125 22071 F27 paper rings with allergen 01 x 25 3.20 80.00Beef, raw

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EP F029-0110 22350 F29 paper rings with allergen 01 x 10 3.20 32.00Banana

EP F030-0110 22353 F30 paper rings with allergen 01 x 10 3.20 32.00Grapefruit

EP F031-0125 22072 F31 paper rings with allergen 01 x 25 3.20 80.00Carrot

EP F032-0110 22354 F32 paper rings with allergen 01 x 10 3.20 32.00Lemon

EP F033-0125 22073 F33 paper rings with allergen 01 x 25 3.20 80.00Orange

EP F034-0110 22646 F34 paper rings with allergen 01 x 10 3.20 32.00Tangerine

EP F035-0125 22074 F35 paper rings with allergen 01 x 25 3.20 80.00Potato

EP F036-0110 22355 F36 paper rings with allergen 01 x 10 3.20 32.00Coconut

EP F037-0110 22356 F37 paper rings with allergen 01 x 10 3.20 32.00Mussel

EP F038-0110 22647 F38 paper rings with allergen 01 x 10 3.20 32.00Spinach

EP F039-0110 22648 F39 paper rings with allergen 01 x 10 3.20 32.00Cabbage, white

EP F040-0110 22357 F40 paper rings with allergen 01 x 10 3.20 32.00Tuna

EP F041-0110 22358 F41 paper rings with allergen 01 x 10 3.20 32.00Salmon

EP F043-0110 22359 F43 paper rings with allergen 01 x 10 3.20 32.00Brewer’s yeast Saccharomyces carlsbergensis

EP F044-0110 22360 F44 paper rings with allergen 01 x 10 3.20 32.00Strawberry

EP F045-0110 22361 F45 paper rings with allergen 01 x 10 3.20 32.00Baker’s yeast Saccharomyces cerevisiae

EP F046-0110 22649 F46 paper rings with allergen 01 x 10 3.20 32.00Pepper, green

EP F047-0110 22362 F47 paper rings with allergen 01 x 10 3.20 32.00Garlic

EP F049-0110 22363 F49 paper rings with allergen 01 x 10 3.20 32.00Apple

EP F050-0110 22650 F50 paper rings with allergen 01 x 10 3.20 32.00Grape

EP F051-0110 22651 F51 paper rings with allergen 01 x 10 3.20 32.00Soy

EP F055-0110 22364 F55 paper rings with allergen 01 x 10 3.20 32.00Eel

EP F056-0110 22365 F56 paper rings with allergen 01 x 10 3.20 32.00Sea perch

EP F057-0110 22366 F57 paper rings with allergen 01 x 10 3.20 32.00Goose meat

EP F058-0110 22367 F58 paper rings with allergen 01 x 10 3.20 32.00Duck meat

EP F062-0110 22652 F62 paper rings with allergen 01 x 10 3.20 32.00Cauliflower, cooked

EP F063-0110 22653 F63 paper rings with allergen 01 x 10 3.20 32.00Beef, cooked

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP F066-0110 22812 F66 paper rings with allergen 01 x 10 3.20 32.00Leek

EP F068-0110 22654 F68 paper rings with allergen 01 x 10 3.20 32.00Ovomucoid

EP F070-0110 22655 F70 paper rings with allergen 01 x 10 3.20 32.00Swiss cheese

EP F071-0110 22368 F71 paper rings with allergen 01 x 10 3.20 32.00Spiny lobster

EP F072-0110 22369 F72 paper rings with allergen 01 x 10 3.20 32.00Pineapple

EP F073-0110 22370 F73 paper rings with allergen 01 x 10 3.20 32.00Cocoa

EP F074-0110 22371 F74 paper rings with allergen 01 x 10 3.20 32.00Coffee

EP F075-0125 22075 F75 paper rings with allergen 01 x 25 3.20 80.00Hen’s egg yolk

EP F076-0110 22372 F76 paper rings with allergen 01 x 10 3.20 32.00alpha-lactalbumin

EP F077-0110 22373 F77 paper rings with allergen 01 x 10 3.20 32.00beta-lactoglobulin

EP F078-0110 22374 F78 paper rings with allergen 01 x 10 3.20 32.00Casein

EP F079-0110 22375 F79 paper rings with allergen 01 x 10 3.20 32.00Gluten (Gliadin)

EP F080-0110 22376 F80 paper rings with allergen 01 x 10 3.20 32.00Lobster

EP F081-0110 22377 F81 paper rings with allergen 01 x 10 3.20 32.00Cheddar cheese

EP F082-0110 22378 F82 paper rings with allergen 01 x 10 3.20 32.00Blue cheese

EP F083-0110 22379 F83 paper rings with allergen 01 x 10 3.20 32.00Chicken

EP F084-0110 22380 F84 paper rings with allergen 01 x 10 3.20 32.00Kiwi fruit

EP F085-0110 22381 F85 paper rings with allergen 01 x 10 3.20 32.00Celery

EP F086-0110 22382 F86 paper rings with allergen 01 x 10 3.20 32.00Parsley

EP F087-0110 22383 F87 paper rings with allergen 01 x 10 3.20 32.00Melon

EP F088-0110 22384 F88 paper rings with allergen 01 x 10 3.20 32.00Mutton / Lamb

EP F089-0110 22385 F89 paper rings with allergen 01 x 10 3.20 32.00Mustard

EP F090-0110 22386 F90 paper rings with allergen 01 x 10 3.20 32.00Pepper, black

EP F091-0110 22387 F91 paper rings with allergen 01 x 10 3.20 32.00Paprika

EP F092-0110 22388 F92 paper rings with allergen 01 x 10 3.20 32.00Nutmeg

EP F093-0110 22389 F93 paper rings with allergen 01 x 10 3.20 32.00Mango

EP F094-0110 22390 F94 paper rings with allergen 01 x 10 3.20 32.00Pear

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP F095-0110 22391 F95 paper rings with allergen 01 x 10 3.20 32.00Peach

EP F096-0110 22392 F96 paper rings with allergen 01 x 10 3.20 32.00Avocado

EP F097-0110 22393 F97 paper rings with allergen 01 x 10 3.20 32.00Cherry

EP F098-0110 22394 F98 paper rings with allergen 01 x 10 3.20 32.00Millet

EP F099-0110 22395 F99 paper rings with allergen 01 x 10 3.20 32.00Spelt

EP F100-0110 22303 F100 paper rings with allergen 01 x 10 3.20 32.00Lettuce

EP F101-0110 22304 F101 paper rings with allergen 01 x 10 3.20 32.00Amaranth seeds

EP F102-0110 22305 F102 paper rings with allergen 01 x 10 3.20 32.00Malt, made of barley

EP F103-0110 22306 F103 paper rings with allergen 01 x 10 3.20 32.00Pecan nut

EP F104-0110 22307 F104 paper rings with allergen 01 x 10 3.20 32.00Quinoa

EP F105-0125 22065 F105 paper rings with allergen 01 x 25 3.20 80.00Chocolate

EP F106-0110 22308 F106 paper rings with allergen 01 x 10 3.20 32.00Kohlrabi

EP F108-0110 22309 F108 paper rings with allergen 01 x 10 3.20 32.00Onion

EP F109-0110 22310 F109 paper rings with allergen 01 x 10 3.20 32.00Cotton seeds

EP F111-0110 22312 F111 paper rings with allergen 01 x 10 3.20 32.00Peppermint tea

EP F113-0110 22313 F113 paper rings with allergen 01 x 10 3.20 32.00Black tea

EP F122-0110 22742 F122 paper rings with allergen 01 x 10 3.20 32.00Olive, black

EP F126-0110 22611 F126 paper rings with allergen 01 x 10 3.20 32.00Peppermint

EP F128-0110 22743 F128 paper rings with allergen 01 x 10 3.20 32.00Poppy seed

EP F130-0110 22658 F130 paper rings with allergen 01 x 10 3.20 32.00Turkey

EP F132-0110 22744 F132 paper rings with allergen 01 x 10 3.20 32.00Bean, green

EP F142-0110 22745 F142 paper rings with allergen 01 x 10 3.20 32.00Comfrey

EP F144-0110 22746 F144 paper rings with allergen 01 x 10 3.20 32.00Pistachio

EP F145-0110 22747 F145 paper rings with allergen 01 x 10 3.20 32.00Fig

EP F147-0110 22748 F147 paper rings with allergen 01 x 10 3.20 32.00Hibiscus tea

EP F148-0110 22612 F148 paper rings with allergen 01 x 10 3.20 32.00Plum

EP F149-0110 22749 F149 paper rings with allergen 01 x 10 3.20 32.00Papaya

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP F150-0110 22613 F150 paper rings with allergen 01 x 10 3.20 32.00Edam cheese

EP F151-0110 22750 F151 paper rings with allergen 01 x 10 3.20 32.00Courgette (zucchini)

EP F152-0110 22614 F152 paper rings with allergen 01 x 10 3.20 32.00Apricot

EP F153-0110 22615 F153 paper rings with allergen 01 x 10 3.20 32.00Wheat bran

EP F154-0110 22751 F154 paper rings with allergen 01 x 10 3.20 32.00St. John’s bread

EP F156-0110 22616 F156 paper rings with allergen 01 x 10 3.20 32.00Raspberry

EP F158-0110 22617 F158 paper rings with allergen 01 x 10 3.20 32.00Cashew nut

EP F159-0110 22752 F159 paper rings with allergen 01 x 10 3.20 32.00Chickpea

EP F160-0110 22753 F160 paper rings with allergen 01 x 10 3.20 32.00Sardine

EP F162-0110 22618 F162 paper rings with allergen 01 x 10 3.20 32.00Dover sole

EP F163-0110 22619 F163 paper rings with allergen 01 x 10 3.20 32.00Pike

EP F164-0110 22754 F164 paper rings with allergen 01 x 10 3.20 32.00Swordfish

EP F165-0110 22659 F165 paper rings with allergen 01 x 10 3.20 32.00Veal, raw

EP F166-0110 22755 F166 paper rings with allergen 01 x 10 3.20 32.00Chinese cabbage

EP F167-0110 22756 F167 paper rings with allergen 01 x 10 3.20 32.00Rabbit meat, raw

EP F168-0110 22660 F168 paper rings with allergen 01 x 10 3.20 32.00Milk powder

EP F170-0110 22620 F170 paper rings with allergen 01 x 10 3.20 32.00Nectarine

EP F171-0110 22621 F171 paper rings with allergen 01 x 10 3.20 32.00Currant, red

EP F172-0110 22758 F172 paper rings with allergen 01 x 10 3.20 32.00Artichoke

EP F173-0110 22759 F173 paper rings with allergen 01 x 10 3.20 32.00Gurnard

EP F175-0110 22622 F175 paper rings with allergen 01 x 10 3.20 32.00Blackberry

EP F176-0110 22760 F176 paper rings with allergen 01 x 10 3.20 32.00Aubergine (eggplant)

EP F177-0110 22761 F177 paper rings with allergen 01 x 10 3.20 32.00Oyster

EP F178-0110 22623 F178 paper rings with allergen 01 x 10 3.20 32.00Haddock

EP F179-0110 22762 F179 paper rings with allergen 01 x 10 3.20 32.00Rock shrimp

EP F180-0110 22763 F180 paper rings with allergen 01 x 10 3.20 32.00Carp

EP F181-0110 22764 F181 paper rings with allergen 01 x 10 3.20 32.00Shark

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP F182-0110 22765 F182 paper rings with allergen 01 x 10 3.20 32.00Cranberry

EP F185-0110 22766 F185 paper rings with allergen 01 x 10 3.20 32.00Cabbage, red

EP F187-0110 22661 F187 paper rings with allergen 01 x 10 3.20 32.00Sheep’s cheese

EP F188-0110 22624 F188 paper rings with allergen 01 x 10 3.20 32.00Soy flour

EP F189-0110 22625 F189 paper rings with allergen 01 x 10 3.20 32.00Rye bran

EP F190-0110 22626 F190 paper rings with allergen 01 x 10 3.20 32.00Barley bran

EP F191-0110 22767 F191 paper rings with allergen 01 x 10 3.20 32.00Pumpkin

EP F192-0110 22768 F192 paper rings with allergen 01 x 10 3.20 32.00Quail

EP F193-0110 22769 F193 paper rings with allergen 01 x 10 3.20 32.00Spelt, unripe

EP F194-0110 22770 F194 paper rings with allergen 01 x 10 3.20 32.00Pepperoni

EP F195-0110 22627 F195 paper rings with allergen 01 x 10 3.20 32.00Soy milk

EP F196-0110 22662 F196 paper rings with allergen 01 x 10 3.20 32.00Halibut

EP F197-0110 22628 F197 paper rings with allergen 01 x 10 3.20 32.00Pine kernels/ nuts

EP F198-0110 22629 F198 paper rings with allergen 01 x 10 3.20 32.00Gouda cheese

EP F199-0110 22771 F199 paper rings with allergen 01 x 10 3.20 32.00Raisin

EP F201-0110 22772 F201 paper rings with allergen 01 x 10 3.20 32.00Chanterelle, yellow

EP F203-0110 22773 F203 paper rings with allergen 01 x 10 3.20 32.00Pomegranate

EP F205-0110 22630 F205 paper rings with allergen 01 x 10 3.20 32.00Goat’s cheese

EP F206-0110 22320 F206 paper rings with allergen 01 x 10 3.20 32.00Mackerel

EP F209-0110 22775 F209 paper rings with allergen 01 x 10 3.20 32.00Sage tea

EP F210-0110 22631 F210 paper rings with allergen 01 x 10 3.20 32.00Wheat

EP F212-0110 22322 F212 paper rings with allergen 01 x 10 3.20 32.00Mushroom

EP F213-0110 22776 F213 paper rings with allergen 01 x 10 3.20 32.00Rhubarb

EP F214-0110 22777 F214 paper rings with allergen 01 x 10 3.20 32.00Radish

EP F215-0110 22778 F215 paper rings with allergen 01 x 10 3.20 32.00Starch (Maize)

EP F217-0110 22633 F217 paper rings with allergen 01 x 10 3.20 32.00Soy protein

EP F218-0110 22634 F218 paper rings with allergen 01 x 10 3.20 32.00Lecithin

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP F219-0110 22635 F219 paper rings with allergen 01 x 10 3.20 32.00Goat milk

EP F220-0110 22779 F220 paper rings with allergen 01 x 10 3.20 32.00Anchovy

EP F221-0110 22819 F221 paper rings with allergen 01 x 10 3.20 32.00Bamboo shoots

EP F222-0110 22780 F222 paper rings with allergen 01 x 10 3.20 32.00Pumpkin seeds

EP F224-0110 22781 F224 paper rings with allergen 01 x 10 3.20 32.00Beetroot

EP F226-0110 22782 F226 paper rings with allergen 01 x 10 3.20 32.00Duck

EP F227-0110 22783 F227 paper rings with allergen 01 x 10 3.20 32.00Deer

EP F228-0110 22784 F228 paper rings with allergen 01 x 10 3.20 32.00Wild pig

EP F229-0110 22785 F229 paper rings with allergen 01 x 10 3.20 32.00Blueberry

EP F230-0110 22820 F230 paper rings with allergen 01 x 10 3.20 32.00Caviar

EP F231-0110 22325 F231 paper rings with allergen 01 x 10 3.20 32.00Milk, cooked

EP F232-0110 22787 F232 paper rings with allergen 01 x 10 3.20 32.00Monkfish

EP F233-0110 22788 F233 paper rings with allergen 01 x 10 3.20 32.00Green kale

EP F234-0110 22326 F234 paper rings with allergen 01 x 10 3.20 32.00Vanilla pod

EP F235-0110 22327 F235 paper rings with allergen 01 x 10 3.20 32.00Lentil

EP F238-0110 22328 F238 paper rings with allergen 01 x 10 3.20 32.00alpha-Lactalbumin, cooked

EP F239-0110 22329 F239 paper rings with allergen 01 x 10 3.20 32.00beta-Lactoglobulin, cooked

EP F240-0110 22331 F240 paper rings with allergen 01 x 10 3.20 32.00Casein, cooked

EP F244-0110 22332 F244 paper rings with allergen 01 x 10 3.20 32.00Cucumber

EP F247-0110 22299 F247 paper rings with allergen 01 x 10 3.20 32.00Honey

EP F254-0110 22333 F254 paper rings with allergen 01 x 10 3.20 32.00Plaice

EP F258-0110 22334 F258 paper rings with allergen 01 x 10 3.20 32.00Squid (Inkfish)

EP F260-0110 22335 F260 paper rings with allergen 01 x 10 3.20 32.00Broccoli

EP F261-0110 22336 F261 paper rings with allergen 01 x 10 3.20 32.00Asparagus

EP F265-0110 22337 F265 paper rings with allergen 01 x 10 3.20 32.00Caraway

EP F267-0110 22338 F267 paper rings with allergen 01 x 10 3.20 32.00Cardamon

EP F268-0110 22339 F268 paper rings with allergen 01 x 10 3.20 32.00Clove

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP F269-0110 22340 F269 paper rings with allergen 01 x 10 3.20 32.00Basil

EP F270-0110 22341 F270 paper rings with allergen 01 x 10 3.20 32.00Ginger

EP F271-0110 22342 F271 paper rings with allergen 01 x 10 3.20 32.00Anise

EP F272-0110 22343 F272 paper rings with allergen 01 x 10 3.20 32.00Tarragon

EP F273-0110 22344 F273 paper rings with allergen 01 x 10 3.20 32.00Thyme

EP F274-0110 22345 F274 paper rings with allergen 01 x 10 3.20 32.00Marjoram

EP F275-0110 22346 F275 paper rings with allergen 01 x 10 3.20 32.00Lovage

EP F276-0110 22347 F276 paper rings with allergen 01 x 10 3.20 32.00Fennel

EP F281-0110 22348 F281 paper rings with allergen 01 x 10 3.20 32.00Curry

EP F284-0110 22349 F284 paper rings with allergen 01 x 10 3.20 32.00Turkey

EP F290-0125 22092 F290 paper rings with allergen 01 x 25 3.20 80.00Milk

EP F291-0110 22351 F291 paper rings with allergen 01 x 10 3.20 32.00Cauliflower

EP F292-0110 22638 F292 paper rings with allergen 01 x 10 3.20 32.00Maize (Corn)

EP F293-0110 22791 F293 paper rings with allergen 01 x 10 3.20 32.00Iceberg lettuce

EP F294-0110 22352 F294 paper rings with allergen 01 x 10 3.20 32.00Grenadilla (Passion fruit)

EP F296-0110 22794 F296 paper rings with allergen 01 x 10 3.20 32.00Gelatine, bovine

EP F297-0110 22795 F297 paper rings with allergen 01 x 10 3.20 32.00Potato flour

EP F298-0110 22796 F298 paper rings with allergen 01 x 10 3.20 32.00Coconut flakes

EP F299-0110 22797 F299 paper rings with allergen 01 x 10 3.20 32.00Parmesan cheese

EP F300-0110 22798 F300 paper rings with allergen 01 x 10 3.20 32.00Horse

EP F301-0110 22799 F301 paper rings with allergen 01 x 10 3.20 32.00Sorrel

EP F302-0110 22800 F302 paper rings with allergen 01 x 10 3.20 32.00Sauerkraut

EP F303-0110 22801 F303 paper rings with allergen 01 x 10 3.20 32.00Snail

EP F304-0110 22802 F304 paper rings with allergen 01 x 10 3.20 32.00Savoy cabbage

EP F306-0110 22639 F306 paper rings with allergen 01 x 10 3.20 32.00Guar flour

EP F307-0110 22640 F307 paper rings with allergen 01 x 10 3.20 32.00Bay leaf

EP F308-0110 22641 F308 paper rings with allergen 01 x 10 3.20 32.00Cinnamon

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP F309-0110 22642 F309 paper rings with allergen 01 x 10 3.20 32.00Coriander

EP F310-0110 22643 F310 paper rings with allergen 01 x 10 3.20 32.00Oregano

EP F311-0110 22644 F311 paper rings with allergen 01 x 10 3.20 32.00Peppercorn, green

EP F312-0110 22645 F312 paper rings with allergen 01 x 10 3.20 32.00Pepper, white

EP F313-0110 22803 F313 paper rings with allergen 01 x 10 3.20 32.00Chilli

EP F314-0110 22804 F314 paper rings with allergen 01 x 10 3.20 32.00Savory

EP F315-0110 22805 F315 paper rings with allergen 01 x 10 3.20 32.00Dill

EP F316-0110 22806 F316 paper rings with allergen 01 x 10 3.20 32.00Chervil

EP F317-0110 22807 F317 paper rings with allergen 01 x 10 3.20 32.00Balm

EP F318-0110 22808 F318 paper rings with allergen 01 x 10 3.20 32.00Rosemary

EP F319-0110 22809 F319 paper rings with allergen 01 x 10 3.20 32.00Sage

EP F320-0110 22810 F320 paper rings with allergen 01 x 10 3.20 32.00Chive

EP F321-0110 22811 F321 paper rings with allergen 01 x 10 3.20 32.00Juniper berry

EP F322-0110 22656 F322 paper rings with allergen 01 x 10 3.20 32.00Ovalbumin

EP F323-0110 22657 F323 paper rings with allergen 01 x 10 3.20 32.00Camembert

EP F324-0110 22740 F324 paper rings with allergen 01 x 10 3.20 32.00Clam

EP F325-0110 22774 F325 paper rings with allergen 01 x 10 3.20 32.00Bean, red

EP F326-0110 22632 F326 paper rings with allergen 01 x 10 3.20 32.00Currant, black

EP F327-0110 22637 F327 paper rings with allergen 01 x 10 3.20 32.00Wine vinegar

EP F328-0110 22790 F328 paper rings with allergen 01 x 10 3.20 32.00Gooseberry

EP F329-0110 22815 F329 paper rings with allergen 01 x 10 3.20 32.00Chamomile tea

EP F330-0110 22816 F330 paper rings with allergen 01 x 10 3.20 32.00Line seed

EP F331-0110 22741 F331 paper rings with allergen 01 x 10 3.20 32.00Brussels sprouts

EP F332-0110 22786 F332 paper rings with allergen 01 x 10 3.20 32.00Lychee chinensis

EP F333-0110 22789 F333 paper rings with allergen 01 x 10 3.20 32.00Chicory

EP F334-0110 22792 F334 paper rings with allergen 01 x 10 3.20 32.00Endive

EP F335-0110 22814 F335 paper rings with allergen 01 x 10 3.20 32.00Roquefort

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP F336-0110 22886 F336 paper rings with allergen 01 x 10 3.20 32.00Glutamate

EP FS11-0125 22152 FS11 paper rings with 01 x 25 3.20 80.00Nuts allergen mixture

(F13, F17, F18, F20, F36)

EP FS12-0125 22153 FS12 paper rings with 01 x 25 3.20 80.00Seafood allergen mixture

(F3, F24, F37, F40, F41)

EP FS13-0125 22154 FS13 paper rings with 01 x 25 3.20 80.00Mixed cereals allergen mixture

(F4, F7, F8, F10, F11)

EP FS14-0110 22981 FS14 paper rings with 01 x 10 3.20 32.00Fish allergen mixture

(F3, F21, F206, F254)

EP FS15-0125 22155 FS15 paper rings with 01 x 25 3.20 80.00Baby food allergen mixture

(F1, F2, F4, F13, F14)

EP FS16-0110 22951 FS16 paper rings with 01 x 10 3.20 32.00Food I allergen mixture

(F15, F12, F235, F14, F13)

EP FS17-0110 22952 FS17 paper rings with 01 x 10 3.20 32.00Food II allergen mixture

(F4, F5, F6, F99)

EP FS18-0110 22953 FS18 paper rings with 01 x 10 3.20 32.00Food III allergen mixture

(F11, F8, F18, F101, F104)

EP FS19-0110 22954 FS19 paper rings with 01 x 10 3.20 32.00Food IV allergen mixture

(F49, F94, F95, F97)

EP FS20-0110 22955 FS20 paper rings with 01 x 10 3.20 32.00Food V (safflower oil, allergen mixture

U87, F100, F272)

EP FS21-0125 22169 FS21 paper rings with 01 x 25 3.20 80.00Fruit I allergen mixture

(F29, F33, F95, F49)

EP FS22-0125 22170 FS22 paper rings with 01 x 25 3.20 80.00Fruit II allergen mixture

(F32, F44, F 72, F94)

EP FS23-0125 22172 FS23 paper rings with 01 x 25 3.20 80.00Flours I allergen mixture

(F7, F5, F4, F79)

EP FS24-0125 22173 FS24 paper rings with 01 x 25 3.20 80.00Vegetables I allergen mixture

(F12, F15, F31, F35)

EP FS25-0125 22174 FS25 paper rings with 01 x 25 3.20 80.00Vegetables II allergen mixture

(F25, F39, F46, F38)

EP FS26-0110 22964 FS26 paper rings with 01 x 10 3.20 32.00Vegetables III allergen mixture

(F14, F85, F108, F212)

EP FS27-0110 22968 FS27 paper rings with 01 x 10 3.20 32.00Cheese allergen mixture

( F70, F81, F82, F150 )

EP FS28-0110 22970 FS28 paper rings with 01 x 10 3.20 32.00Meat allergen mixture

(F26, F27, F88)

EP FS29-0110 22975 FS29 paper rings with 01 x 10 3.20 32.00Poultry allergen mixture

(F57, F58, F83, F130)

EP FS30-0110 22976 FS30 paper rings with 01 x 10 3.20 32.00Flours II allergen mixture

(F4, F5, F6, F7, F8)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

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EP FS31-0110 22979 FS31 paper rings with 01 x 10 3.20 32.00Food VI allergen mixture

(F3, F8, F17, F23, F25)

EP FS32-0110 22982 FS32 paper rings with 01 x 10 3.20 32.00Citrus fruits allergen mixture

(F30, F32, F33, F34)

EP FS55-0125 22178 FS55 paper rings with 01 x 25 3.20 80.00Multiscreen soy I allergen mixture

(F14, F51, F188, F195, F217)

EP FS70-0110 22956 FS70 paper rings with 01 x 10 3.20 32.00Spices I allergen mixture

(F272, F274, F273, F275)

EP FS71-0125 22156 FS71 paper rings with 01 x 25 3.20 80.00Spices II allergen mixture

(F265, F268, F92, F267)

EP FS72-0110 22957 FS72 paper rings with 01 x 10 3.20 32.00Spices III allergen mixture

(F271, F270, F269, F276)

EP FS73-0110 22958 FS73 paper rings with 01 x 10 3.20 32.00Spices IV allergen mixture

(F275, F265, F276, F271)

EP FS74-0110 22959 FS74 paper rings with 01 x 10 3.20 32.00Spices V allergen mixture

(F274, F273, F269, F111)

EP FS75-0125 22175 FS75 paper rings with 01 x 25 3.20 80.00Spices VI allergen mixture

(F271,F281,F265,F47)

EP FS76-0125 22176 FS76 paper rings with 01 x 25 3.20 80.00Spices VII allergen mixture

(F89, F90, F91, F307)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Food)

PreviousOrder No.

Price (€)per Package

Antibodiesof Class IgE against

Substrate FormatOrder No. Price (€)per Ring

Allercoat™ 6 System: Allergen Rings (Grasses)

PreviousOrder No.

EP G001-0110 22396 G1 paper rings with allergen 01 x 10 3.20 32.00Sweet vernal grass

EP G002-0110 22397 G2 paper rings with allergen 01 x 10 3.20 32.00Bermuda grass

EP G003-0110 22398 G3 paper rings with allergen 01 x 10 3.20 32.00Cocksfoot

EP G004-0110 22399 G4 paper rings with allergen 01 x 10 3.20 32.00Fescue, meadow

EP G005-0125 22076 G5 paper rings with allergen 01 x 25 3.20 80.00Rye grass, perennial

EP G006-0125 22077 G6 paper rings with allergen 01 x 25 3.20 80.00Timothy grass

EP G008-0110 22401 G8 paper rings with allergen 01 x 10 3.20 32.00Kentucky blue (June) grass

EP G009-0110 22402 G9 paper rings with allergen 01 x 10 3.20 32.00Bentgrass

EP G010-0110 22403 G10 paper rings with allergen 01 x 10 3.20 32.00Johnson Grass

EP G011-0110 22406 G11 paper rings with allergen 01 x 10 3.20 32.00Brome, smooth

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EP G012-0125 22078 G12 paper rings with allergen 01 x 25 3.20 80.00Rye, cultivated

EP G013-0110 22407 G13 paper rings with allergen 01 x 10 3.20 32.00Velvet grass

EP G014-0110 22408 G14 paper rings with allergen 01 x 10 3.20 32.00Oats, cultivated

EP G016-0110 22409 G16 paper rings with allergen 01 x 10 3.20 32.00Meadow foxtail

EP G017-0110 22410 G17 paper rings with allergen 01 x 10 3.20 32.00Bahia grass

EP G018-0110 22411 G18 paper rings with allergen 01 x 10 3.20 32.00Barley, cultivated

EP G019-0110 22821 G19 paper rings with allergen 01 x 10 3.20 32.00Dogtail grass, crested

EP G020-0110 22412 G20 paper rings with allergen 01 x 10 3.20 32.00Maize (Corn)

EP G021-0110 22828 G21 paper rings with allergen 01 x 10 3.20 32.00Twich (Couch) grass

EP G070-0110 22413 G70 paper rings with allergen 01 x 10 3.20 32.00Elymus

EP G071-0110 22822 G71 paper rings with allergen 01 x 10 3.20 32.00Oat grass

EP G072-0110 22823 G72 paper rings with allergen 01 x 10 3.20 32.00Knot grass

EP G073-0110 22824 G73 paper rings with allergen 01 x 10 3.20 32.00Elymus triticoides

EP G074-0110 22825 G74 paper rings with allergen 01 x 10 3.20 32.00Phalaris arundinacea

EP G075-0110 22826 G75 paper rings with allergen 01 x 10 3.20 32.00Hordeum leporinum

EP G076-0110 22827 G76 paper rings with allergen 01 x 10 3.20 32.00Wild oat

EP G100-0110 22404 G100 paper rings with allergen 01 x 10 3.20 32.00Russian thistle (Saltwort)

EP G101-0110 22405 G101 paper rings with allergen 01 x 10 3.20 32.00Wheat

EP GIH1-0125 22161 IHS1 paper rings with 01 x 25 3.20 80.00Inhalation I allergen mixture

(G6, W6, W9, W21, T3)

EP GIH2-0125 22162 IHS2 paper rings with 01 x 25 3.20 80.00Inhalation II allergen mixture

(D2, E1, E2, E3, M6)

EP GIH3-0110 22960 IHS3 paper rings with 01 x 10 3.20 32.00Inhalation III allergen mixture

(D1, D2, E1, E2, M5)

EP GIH4-0125 22179 IHS4 paper rings with 01 x 25 3.20 80.00Inhalation IV allergen mixture

(G2, G5, G17, W1, W9, W10)

EP GS01-0125 22158 GS1 paper rings with 01 x 25 3.20 80.00Grass allergen mixture

(G1,G2, G5, G6, G10)

EP GS11-0125 22157 GS11 paper rings with 01 x 25 3.20 80.00Grass, early flowering allergen mixture(G3, G4, G5, G6, G8)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Grasses)

PreviousOrder No.

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EP GS14-0125 22159 GS14 paper rings with 01 x 25 3.20 80.00Grass, late flowering allergen mixture

(G1, G5, G7, G12, G13)

EP GS20-0125 22177 GS20 paper rings with 01 x 25 3.20 80.00Cereal pollen allergen mixture

(G12, G14, G18, G20, G101)

EP GS22-0125 22180 GS22 paper rings with 01 x 25 3.20 80.00Grass Mix Australia allergen mixture

(G2, G5, G6, G8, G10, G17)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Grasses)

PreviousOrder No.

EP H001-0125 22079 H1 paper rings with allergen 01 x 25 3.20 80.00House dust Greer Labs

EP H002-0125 22080 H2 paper rings with allergen 01 x 25 3.20 80.00House dust Hollister-Stier

EP HS12-0125 22160 HS12 paper rings with 01 x 25 3.20 80.00Mites allergen mixture

(H2, D1, D2, I6)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (House Dust)

PreviousOrder No.

Price (€)per Package

Antibodiesof Class IgE against

Substrate FormatOrder No. Price (€)per Ring

Allercoat™ 6 System: Allergen Rings (Insects)

PreviousOrder No.

EP I001-0110 22415 I1 paper rings with allergen 01 x 10 3.20 32.00Honeybee, venom

EP I002-0110 22416 I2 paper rings with allergen 01 x 10 3.20 32.00White faced hornet (Dolichovespula maculata)

EP I003-0110 22417 I3 paper rings with allergen 01 x 10 3.20 32.00Wasp (Yellow jacket), venom

EP I004-0110 22418 I4 paper rings with allergen 01 x 10 3.20 32.00Paper wasp (Polistes apachus)

EP I005-0110 22419 I5 paper rings with allergen 01 x 10 3.20 32.00Yellow hornet (Dolichovespula arenaria)

EP I006-0110 22420 I6 paper rings with allergen 01 x 10 3.20 32.00German cockroach

EP I007-0110 22421 I7 paper rings with allergen 01 x 10 3.20 32.00Bumble bee, venom

EP I010-0110 22829 I10 paper rings with allergen 01 x 10 3.20 32.00Paper wasp, venom

EP I011-0110 22830 I11 paper rings with allergen 01 x 10 3.20 32.00Phospholipase

EP I012-0110 22422 I12 paper rings with allergen 01 x 10 3.20 32.00Black ant

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EP I014-0110 22423 I14 paper rings with allergen 01 x 10 3.20 32.00Horsefly

EP I015-0110 22831 I15 paper rings with allergen 01 x 10 3.20 32.00House fly

EP I070-0110 22424 I70 paper rings with allergen 01 x 10 3.20 32.00Fire ant

EP I071-0110 22425 I71 paper rings with allergen 01 x 10 3.20 32.00Mosquito (Gnat)

EP I073-0110 22427 I73 paper rings with allergen 01 x 10 3.20 32.00Red gnat larvae

EP I074-0110 22832 I74 paper rings with allergen 01 x 10 3.20 32.00Waterflea

EP I075-0110 22428 I75 paper rings with allergen 01 x 10 3.20 32.00Hornet, venom

EP I076-0110 22569 I76 paper rings with allergen 01 x 10 3.20 32.00Trogoderma angustum

EP I077-0110 22429 I77 paper rings with allergen 01 x 10 3.20 32.00Rice flour beetle

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Insects)

PreviousOrder No.

Price (€)per Package

Antibodiesof Class IgE against

Substrate FormatOrder No. Price (€)per Ring

Allercoat™ 6 System: Allergen Rings (Moulds)

PreviousOrder No.

EP M001-0125 22081 M1 paper rings with allergen 01 x 25 3.20 80.00Penicillium notatum

EP M002-0125 22082 M2 paper rings with allergen 01 x 25 3.20 80.00Cladosporium herbarum

EP M003-0125 22083 M3 paper rings with allergen 01 x 25 3.20 80.00Aspergillus fumigatus

EP M004-0110 22430 M4 paper rings with allergen 01 x 10 3.20 32.00Mucor racemosus

EP M005-0125 22084 M5 paper rings with allergen 01 x 25 3.20 80.00Candida albicans

EP M006-0125 22085 M6 paper rings with allergen 01 x 25 3.20 80.00Alternaria tenuis

EP M007-0110 22431 M7 paper rings with allergen 01 x 10 3.20 32.00Botrytis cinerea

EP M008-0110 22432 M8 paper rings with allergen 01 x 10 3.20 32.00Helminthosporium halodes

EP M009-0110 22433 M9 paper rings with allergen 01 x 10 3.20 32.00Fusarium culmorum

EP M010-0110 22434 M10 paper rings with allergen 01 x 10 3.20 32.00Stemphylium botryosum

EP M011-0110 22435 M11 paper rings with allergen 01 x 10 3.20 32.00Rhizopus nigricans

EP M012-0110 22436 M12 paper rings with allergen 01 x 10 3.20 32.00Aureobasidium pullulans

EP M013-0110 22437 M13 paper rings with allergen 01 x 10 3.20 32.00Phoma betae

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EP M014-0110 22438 M14 paper rings with allergen 01 x 10 3.20 32.00Epicoccum purpurascens

EP M015-0110 22439 M15 paper rings with allergen 01 x 10 3.20 32.00Trichoderma viride

EP M016-0110 22440 M16 paper rings with allergen 01 x 10 3.20 32.00Curvularia lunata

EP M017-0110 22441 M17 paper rings with allergen 01 x 10 3.20 32.00Aspergillus amstelodami

EP M018-0110 22442 M18 paper rings with allergen 01 x 10 3.20 32.00Aspergillus terreus

EP M019-0110 22443 M19 paper rings with allergen 01 x 10 3.20 32.00Aspergillus versicolor

EP M020-0110 22444 M20 paper rings with allergen 01 x 10 3.20 32.00Neurospora sitophila

EP M021-0110 22446 M21 paper rings with allergen 01 x 10 3.20 32.00Paecilomyces spec.

EP M023-0110 22448 M23 paper rings with allergen 01 x 10 3.20 32.00Serpula lacrymans

EP M024-0110 22449 M24 paper rings with allergen 01 x 10 3.20 32.00Sporobolomyces roseus

EP M025-0110 22450 M25 paper rings with allergen 01 x 10 3.20 32.00Aspergillus flavus

EP M026-0110 22451 M26 paper rings with allergen 01 x 10 3.20 32.00Ustilago tritici

EP M027-0110 22452 M27 paper rings with allergen 01 x 10 3.20 32.00Micropolyspora faeni

EP M028-0110 22667 M28 paper rings with allergen 01 x 10 3.20 32.00Aspergillus repens

EP M030-0110 22836 M30 paper rings with allergen 01 x 10 3.20 32.00Penicillium roqueforti

EP M031-0110 22837 M31 paper rings with allergen 01 x 10 3.20 32.00Penicillium viridicatum

EP M032-0110 22668 M32 paper rings with allergen 01 x 10 3.20 32.00Cladosporium cladosporioides

EP M037-0110 22838 M37 paper rings with allergen 01 x 10 3.20 32.00Trichophyton mentagrophytes

EP M038-0110 22839 M38 paper rings with allergen 01 x 10 3.20 32.00Trichophyton verrucosum

EP M039-0110 22840 M39 paper rings with allergen 01 x 10 3.20 32.00Trichophyton rubrum

EP M040-0110 22663 M40 paper rings with allergen 01 x 10 3.20 32.00Fusarium moniliforme

EP M041-0110 22664 M41 paper rings with allergen 01 x 10 3.20 32.00Mucor mucedo

EP M042-0110 22665 M42 paper rings with allergen 01 x 10 3.20 32.00Aspergillus clavatus

EP M046-0110 22666 M46 paper rings with allergen 01 x 10 3.20 32.00Mucor spinosus

EP M047-0110 22841 M47 paper rings with allergen 01 x 10 3.20 32.00Cephalosporium acremonium

EP M048-0110 22842 M48 paper rings with allergen 01 x 10 3.20 32.00Aspergillus oryzae

EP M049-0110 22843 M49 paper rings with allergen 01 x 10 3.20 32.00Aspergillus nidulans

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Moulds)

PreviousOrder No.

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EP M053-0110 22671 M53 paper rings with allergen 01 x 10 3.20 32.00Thermopolyspora polyspora

EP M056-0110 22847 M56 paper rings with allergen 01 x 10 3.20 32.00Microsporum canis

EP M058-0110 22833 M58 paper rings with allergen 01 x 10 3.20 32.00Cladosporium fulvum

EP M059-0110 22834 M59 paper rings with allergen 01 x 10 3.20 32.00Penicillium commune

EP M060-0110 22885 M60 paper rings with allergen 01 x 10 3.20 32.00Ulocladium chartarum

EP M061-0110 22835 M61 paper rings with allergen 01 x 10 3.20 32.00Penicillium expansum

EP M062-0110 22670 M62 paper rings with allergen 01 x 10 3.20 32.00Wine yeast

EP M063-0110 22844 M63 paper rings with allergen 01 x 10 3.20 32.00Chaetomium globosum

EP M064-0110 22845 M64 paper rings with allergen 01 x 10 3.20 32.00Penicillium chrysogenum

EP M207-0110 22445 M207 paper rings with allergen 01 x 10 3.20 32.00Aspergillus niger

EP MS01-0125 22163 MS1 paper rings with 01 x 25 3.20 80.00Moulds allergen mixture

(M1, M2, M3, M6)

EP MS02-0110 22966 MS2 paper rings with 01 x 10 3.20 32.00Aspergilli 1 allergen mixture

(M3, M21, M17, M40)

EP MS03-0110 22967 MS3 paper rings with 01 x 10 3.20 32.00Aspergilli 2 allergen mixture

(M19, M28, M207, M18)

EP MS04-0110 22969 MS4 paper rings with 01 x 10 3.20 32.00Penicillia allergen mixture

(M1, M22, M28, M30)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Moulds)

PreviousOrder No.

EP O070-0110 22454 O70 paper rings with allergen 01 x 10 3.20 32.00Seminal fluid

EP O071-0110 22850 O71 paper rings with allergen 01 x 10 3.20 32.00Seminal plasma

EP O072-0110 22851 O72 paper rings with allergen 01 x 10 3.20 32.00Sperm sediment

EP O201-0110 22453 O201 paper rings with allergen 01 x 10 3.20 32.00Tobacco dust

Price (€)per Package

Antibodiesof Class IgE against

Substrate FormatOrder No. Price (€)per Ring

Allercoat™ 6 System: Allergen Rings (Further Allergens)

PreviousOrder No.

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EP P001-0110 22455 P1 paper rings with allergen 01 x 10 3.20 32.00Ascaris

EP P002-0110 22456 P2 paper rings with allergen 01 x 10 3.20 32.00Echinococcus

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Parasites)

PreviousOrder No.

Price (€)per Package

Antibodiesof Class IgE against

Substrate FormatOrder No. Price (€)per Ring

Allercoat™ 6 System: Allergen Rings (Trees)

PreviousOrder No.

EP T001-0110 22458 T1 paper rings with allergen 01 x 10 3.20 32.00Maple

EP T002-0125 22086 T2 paper rings with allergen 01 x 25 3.20 80.00Alder

EP T003-0125 22087 T3 paper rings with allergen 01 x 25 3.20 80.00Birch

EP T004-0125 22088 T4 paper rings with allergen 01 x 25 3.20 80.00Hazel

EP T005-0125 22089 T5 paper rings with allergen 01 x 25 3.20 80.00Beech, European

EP T006-0110 22459 T6 paper rings with allergen 01 x 10 3.20 32.00Cedar, Japanese

EP T007-0110 22460 T7 paper rings with allergen 01 x 10 3.20 32.00Oak

EP T008-0110 22461 T8 paper rings with allergen 01 x 10 3.20 32.00Elm

EP T009-0110 22462 T9 paper rings with allergen 01 x 10 3.20 32.00Olive

EP T010-0110 22463 T10 paper rings with allergen 01 x 10 3.20 32.00Walnut

EP T011-0110 22470 T11 paper rings with allergen 01 x 10 3.20 32.00Planetree

EP T012-0110 22471 T12 paper rings with allergen 01 x 10 3.20 32.00Willow

EP T013-0110 22853 T13 paper rings with allergen 01 x 10 3.20 32.00Mock, orange

EP T014-0110 22472 T14 paper rings with allergen 01 x 10 3.20 32.00Poplar

EP T015-0110 22473 T15 paper rings with allergen 01 x 10 3.20 32.00Ash

EP T016-0110 22474 T16 paper rings with allergen 01 x 10 3.20 32.00Pine

EP T017-0110 22475 T17 paper rings with allergen 01 x 10 3.20 32.00Chestnut, European

EP T018-0110 22476 T18 paper rings with allergen 01 x 10 3.20 32.00Eucalyptus

EP T019-0110 22477 T19 paper rings with allergen 01 x 10 3.20 32.00Mimosa

EP T020-0110 22478 T20 paper rings with allergen 01 x 10 3.20 32.00Privet, common

EP T021-0110 22298 T21 paper rings with allergen 01 x 10 3.20 32.00Lilac, common

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EP T022-0110 22854 T22 paper rings with allergen 01 x 10 3.20 32.00Hawthorn

EP T023-0110 22479 T23 paper rings with allergen 01 x 10 3.20 32.00Cypress

EP T024-0110 22480 T24 paper rings with allergen 01 x 10 3.20 32.00Lime tree

EP T025-0110 22481 T25 paper rings with allergen 01 x 10 3.20 32.00Elder, european

EP T026-0110 22672 T26 paper rings with allergen 01 x 10 3.20 32.00Golden chain

EP T027-0110 22852 T27 paper rings with allergen 01 x 10 3.20 32.00Cedar, mountain

EP T028-0110 22673 T28 paper rings with allergen 01 x 10 3.20 32.00Robinia

EP T029-0110 22855 T29 paper rings with allergen 01 x 10 3.20 32.00Morello cherry

EP T031-0110 22856 T31 paper rings with allergen 01 x 10 3.20 32.00Melaleuca

EP T032-0110 22857 T32 paper rings with allergen 01 x 10 3.20 32.00Orange

EP T033-0110 22858 T33 paper rings with allergen 01 x 10 3.20 32.00Poplar, lombardy

EP T034-0110 22674 T34 paper rings with allergen 01 x 10 3.20 32.00Almond tree

EP T037-0110 22859 T37 paper rings with allergen 01 x 10 3.20 32.00Yew tree

EP T070-0110 22482 T70 paper rings with allergen 01 x 10 3.20 32.00Mulberry, white

EP T100-0110 22464 T100 paper rings with allergen 01 x 10 3.20 32.00Pecan

EP T101-0110 22465 T101 paper rings with allergen 01 x 10 3.20 32.00Walnut, black

EP T102-0110 22466 T102 paper rings with allergen 01 x 10 3.20 32.00Mesquite

EP T103-0110 22467 T103 paper rings with allergen 01 x 10 3.20 32.00Live Oak

EP T104-0110 22468 T104 paper rings with allergen 01 x 10 3.20 32.00Australian pine

EP T107-0110 22469 T107 paper rings with allergen 01 x 10 3.20 32.00Cajeput tree

EP TS01-0110 22961 TS1 paper rings with 01 x 10 3.20 32.00Trees I allergen mixture

(T3, T6, T8, T102, T103)

EP TS02-0110 22962 TS2 paper rings with 01 x 10 3.20 32.00Trees II allergen mixture

(T1,T3,T5,T11,T14,T103)

EP TS15-0125 22164 TS15 paper rings with 01 x 25 3.20 80.00Trees, early flowering allergen mixture(T2, T4, T8, T12, T14)

EP TS16-0125 22165 TS16 paper rings with 01 x 25 3.20 80.00Trees, late flowering allergen mixture(T1, T3, T5, T7, T10)

EP TS17-0110 22971 TS17 paper rings with 01 x 10 3.20 32.00Soft woods allergen mixture

(WD02, WD14, WD06, WD25)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Trees)

PreviousOrder No.

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EP TS18-0110 22972 TS18 paper rings with 01 x 10 3.20 32.00Hard woods allergen mixture

(WD20, WD17, WD12, WD9)

EP TS19-0125 22181 TS19 paper rings with 01 x 25 3.20 80.00Tree Mix Australia allergen mixture

(T104, T12, T18, T19, T107)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Trees)

PreviousOrder No.

Price (€)per Package

Antibodiesof Class IgE against

Substrate FormatOrder No. Price (€)per Ring

Allercoat™ 6 System: Allergen Rings (Environmental Allergens)

PreviousOrder No.

EP U070-0110 22483 U70 paper rings with allergen 01 x 10 3.20 32.00Green coffee bean

EP U071-0110 22484 U71 paper rings with allergen 01 x 10 3.20 32.00Castor bean

EP U072-0110 22485 U72 paper rings with allergen 01 x 10 3.20 32.00Isphagula (Sem. plant. psyll.)

EP U073-0110 22486 U73 paper rings with allergen 01 x 10 3.20 32.00Wild silk

EP U074-0110 22487 U74 paper rings with allergen 01 x 10 3.20 32.00Raw silk, fabric

EP U075-0110 22488 U75 paper rings with allergen 01 x 10 3.20 32.00TDI Isocyanate - HSA

EP U076-0110 22489 U76 paper rings with allergen 01 x 10 3.20 32.00MDI Isocyanate - HSA

EP U077-0110 22490 U77 paper rings with allergen 01 x 10 3.20 32.00HDI Isocyanate - HSA

EP U078-0110 22491 U78 paper rings with allergen 01 x 10 3.20 32.00Ethylene oxide - HSA

EP U079-0110 22492 U79 paper rings with allergen 01 x 10 3.20 32.00Phthalic anhydride - HSA

EP U080-0110 22493 U80 paper rings with allergen 01 x 10 3.20 32.00Hops

EP U081-0110 22494 U81 paper rings with allergen 01 x 10 3.20 32.00Cotton, yarn and fabric

EP U082-0110 22495 U82 paper rings with allergen 01 x 10 3.20 32.00Sheep’s wool

EP U083-0110 22496 U83 paper rings with allergen 01 x 10 3.20 32.00Formaldehyde - HSA

EP U084-0110 22497 U84 paper rings with allergen 01 x 10 3.20 32.00Ficus benjamini

EP U085-0110 22498 U85 paper rings with allergen 01 x 10 3.20 32.00Latex

EP U086-0110 22499 U86 paper rings with allergen 01 x 10 3.20 32.00Trimellitic acid anhydride (TMA - HSA)

EP U087-0110 22500 U87 paper rings with allergen 01 x 10 3.20 32.00Sunflower seeds

EP U088-0110 22501 U88 paper rings with allergen 01 x 10 3.20 32.00Chloramine T - HSA

EP U089-0110 22502 U89 paper rings with allergen 01 x 10 3.20 32.00Alpha-amylase

EP U090-0110 22503 U90 paper rings with allergen 01 x 10 3.20 32.00Lindane - HSA

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EP U091-0110 22504 U91 paper rings with allergen 01 x 10 3.20 32.00PCP - HSA

EP U092-0110 22505 U92 paper rings with allergen 01 x 10 3.20 32.00Pyrethroide - HSA

EP U093-0110 22538 U93 paper rings with allergen 01 x 10 3.20 32.00Maleic anhydride - HSA

EP U094-0110 22506 U94 paper rings with allergen 01 x 10 3.20 32.00Nickel sulphate - HSA

EP U101-0110 22679 U101 paper rings with allergen 01 x 10 3.20 32.00Benzoic acid - HSA

EP U102-0110 22680 U102 paper rings with allergen 01 x 10 3.20 32.00Parabene Propylester - HSA

EP U103-0110 22681 U103 paper rings with allergen 01 x 10 3.20 32.00Sorbic acid - HSA

EP U106-0110 22709 U106 paper rings with allergen 01 x 10 3.20 32.00Benzoicacidester - HSA

EP U107-0110 22683 U107 paper rings with allergen 01 x 10 3.20 32.00Buthylester - HSA

EP U108-0110 22684 U108 paper rings with allergen 01 x 10 3.20 32.00Mercury - HSA

EP U109-0110 22685 U109 paper rings with allergen 01 x 10 3.20 32.00Chromium - HSA

EP U110-0110 22686 U110 paper rings with allergen 01 x 10 3.20 32.00Copper - HSA

EP U111-0110 22687 U111 paper rings with allergen 01 x 10 3.20 32.00Cobalt - HSA

EP U112-0110 22688 U112 paper rings with allergen 01 x 10 3.20 32.00Silver - HSA

EP U113-0110 22689 U113 paper rings with allergen 01 x 10 3.20 32.00Gold - HSA

EP U114-0110 22690 U114 paper rings with allergen 01 x 10 3.20 32.00Platinum - HSA

EP U115-0110 22691 U115 paper rings with allergen 01 x 10 3.20 32.00Tin - HSA

EP U116-0110 22692 U116 paper rings with allergen 01 x 10 3.20 32.00Zinc - HSA

EP U117-0110 22693 U117 paper rings with allergen 01 x 10 3.20 32.00Formic acid - HSA

EP U118-0110 22889 U118 paper rings with allergen 01 x 10 3.20 32.00Chinoline yellow - HSA

EP U119-0110 22890 U119 paper rings with allergen 01 x 10 3.20 32.00Yellow orange - HSA

EP U121-0110 22697 U121 paper rings with allergen 01 x 10 3.20 32.00Parabenemethylester - HSA

EP U122-0110 22698 U122 paper rings with allergen 01 x 10 3.20 32.00Tartrazin - HSA

EP U124-0110 22700 U124 paper rings with allergen 01 x 10 3.20 32.00Palladium - HSA

EP U125-0110 22701 U125 paper rings with allergen 01 x 10 3.20 32.00Lanolin

EP U126-0110 22702 U126 paper rings with allergen 01 x 10 3.20 32.00Straw dust

EP U127-0110 22703 U127 paper rings with allergen 01 x 10 3.20 32.00Rayon

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Environmental Allergens)

PreviousOrder No.

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per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Environmental Allergens)

PreviousOrder No.

EP U128-0110 22704 U128 paper rings with allergen 01 x 10 3.20 32.00Linen

EP U129-0110 22706 U129 paper rings with allergen 01 x 10 3.20 32.00Jute

EP U130-0110 22707 U130 paper rings with allergen 01 x 10 3.20 32.00Amyloglucosidase

EP U131-0110 22864 U131 paper rings with allergen 01 x 10 3.20 32.00Acrilan

EP U132-0110 22865 U132 paper rings with allergen 01 x 10 3.20 32.00Threshing dust

EP U133-0110 22866 U133 paper rings with allergen 01 x 10 3.20 32.00Flax

EP U134-0110 22867 U134 paper rings with allergen 01 x 10 3.20 32.00Ceiba pentandra

EP U135-0110 22868 U135 paper rings with allergen 01 x 10 3.20 32.00Nylon

EP U136-0110 22869 U136 paper rings with allergen 01 x 10 3.20 32.00Silk

EP U137-0110 22870 U137 paper rings with allergen 01 x 10 3.20 32.00Terylene

EP U138-0110 22871 U138 paper rings with allergen 01 x 10 3.20 32.00Wheat threshing dust

EP U139-0110 22872 U139 paper rings with allergen 01 x 10 3.20 32.00Hay dust

EP U140-0110 22708 U140 paper rings with allergen 01 x 10 3.20 32.00Sheep’s wool, raw

EP U141-0110 22705 U141 paper rings with allergen 01 x 10 3.20 32.00Hemicellulase

EP U142-0110 22544 U142 paper rings with allergen 01 x 10 3.20 32.00Alcalase

EP U143-0110 22694 U143 paper rings with allergen 01 x 10 3.20 32.00Sodium sulfate - HSA

EP U144-0110 22793 U144 paper rings with allergen 01 x 10 3.20 32.00Ammonium persulfate - HSA

EP U145-0110 22817 U145 paper rings with allergen 01 x 10 3.20 32.00Henna, red

EP U146-0110 22818 U146 paper rings with allergen 01 x 10 3.20 32.00Collagen

EP US11-0125 22166 US11 paper rings with 01 x 25 3.20 80.00Environmental screen I allergen mixture

(E1, E2, D1, D2, H2)

EP US12-0110 22974 US12 paper rings with 01 x 10 3.20 32.00Environmental screen II allergen mixture

G12, W6, T3, E1, E5, D1, M2)

EP US13-0110 22977 US13 paper rings with 01 x 10 3.20 32.00Synthetic fibres allergen mixture

(U131, U127, U135, U137)

EP US14-0110 22978 US14 paper rings with 01 x 10 3.20 32.00Natural fibres allergen mixture

(U82, U81, U129, U74)

EP US15-0110 22980 US15 paper rings with 01 x 10 3.20 32.00Chemicals I allergen mixture

(U75, U76, U77, U79)

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Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Herbal and Flower Pollen)

PreviousOrder No.

EP W001-0110 22507 W1 paper rings with allergen 01 x 10 3.20 32.00Ragweed, short

EP W002-0110 22508 W2 paper rings with allergen 01 x 10 3.20 32.00Ragweed, western

EP W003-0110 22509 W3 paper rings with allergen 01 x 10 3.20 32.00Ragweed, tall or giant

EP W004-0110 22510 W4 paper rings with allergen 01 x 10 3.20 32.00Ragweed, false

EP W005-0110 22511 W5 paper rings with allergen 01 x 10 3.20 32.00Wormwood

EP W006-0125 22090 W6 paper rings with allergen 01 x 25 3.20 80.00Mugwort

EP W007-0110 22512 W7 paper rings with allergen 01 x 10 3.20 32.00Ox-eye daisy (Marguerite)

EP W008-0110 22513 W8 paper rings with allergen 01 x 10 3.20 32.00Dandelion

EP W009-0125 22091 W9 paper rings with allergen 01 x 25 3.20 80.00Plantain, english

EP W010-0110 22514 W10 paper rings with allergen 01 x 10 3.20 32.00Lamb’s quarter

EP W011-0110 22519 W11 paper rings with allergen 01 x 10 3.20 32.00Russian thistle (Saltwort)

EP W012-0110 22520 W12 paper rings with allergen 01 x 10 3.20 32.00Goldenrod

EP W013-0110 22521 W13 paper rings with allergen 01 x 10 3.20 32.00Cocklebur

EP W014-0110 22522 W14 paper rings with allergen 01 x 10 3.20 32.00Amaranth

EP W015-0110 22523 W15 paper rings with allergen 01 x 10 3.20 32.00Lens-scale

EP W016-0110 22524 W16 paper rings with allergen 01 x 10 3.20 32.00Rough Marsh/ Elder

EP W017-0110 22525 W17 paper rings with allergen 01 x 10 3.20 32.00Firebush

EP W019-0110 22526 W19 paper rings with allergen 01 x 10 3.20 32.00Wall pellitory Parietaria officinalis

EP W021-0110 22527 W21 paper rings with allergen 01 x 10 3.20 32.00Wall pellitory, erect Parietaria judaica

EP W022-0110 22710 W22 paper rings with allergen 01 x 10 3.20 32.00Chrysanthemum

EP W023-0110 22712 W23 paper rings with allergen 01 x 10 3.20 32.00Dahlia

EP W024-0110 22874 W24 paper rings with allergen 01 x 10 3.20 32.00Kochia scoparia

EP W025-0110 22528 W25 paper rings with allergen 01 x 10 3.20 32.00Geranium

EP W026-0110 22713 W26 paper rings with allergen 01 x 10 3.20 32.00Daffodil

EP W027-0110 22714 W27 paper rings with allergen 01 x 10 3.20 32.00Carnation, whole flower

EP W028-0110 22529 W28 paper rings with allergen 01 x 10 3.20 32.00Rose

EP W029-0110 22875 W29 paper rings with allergen 01 x 10 3.20 32.00Sunflower

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EP W030-0110 22530 W30 paper rings with allergen 01 x 10 3.20 32.00Tulip

EP W031-0110 22531 W31 paper rings with allergen 01 x 10 3.20 32.00Rape

EP W032-0110 22532 W32 paper rings with allergen 01 x 10 3.20 32.00Chamomile, wild

EP W033-0110 22533 W33 paper rings with allergen 01 x 10 3.20 32.00Primrose

EP W034-0110 22884 W34 paper rings with allergen 01 x 10 3.20 32.00Clover, red

EP W038-0110 22877 W38 paper rings with allergen 01 x 10 3.20 32.00Marchelder, rough

EP W039-0110 22715 W39 paper rings with allergen 01 x 10 3.20 32.00Lupine

EP W040-0110 22716 W40 paper rings with allergen 01 x 10 3.20 32.00Hyacinth

EP W041-0110 22878 W41 paper rings with allergen 01 x 10 3.20 32.00Alfalfa (Lucerne)

EP W042-0110 22879 W42 paper rings with allergen 01 x 10 3.20 32.00Lady’s mantle

EP W044-0110 22717 W44 paper rings with allergen 01 x 10 3.20 32.00Lily

EP W045-0110 22880 W45 paper rings with allergen 01 x 10 3.20 32.00Euphorbia

EP W046-0110 22718 W46 paper rings with allergen 01 x 10 3.20 32.00Azalea

EP W047-0110 22881 W47 paper rings with allergen 01 x 10 3.20 32.00Hibiscus

EP W048-0110 22882 W48 paper rings with allergen 01 x 10 3.20 32.00Yarrow

EP W049-0110 22719 W49 paper rings with allergen 01 x 10 3.20 32.00Begonia, flowers and leaves

EP W050-0110 22720 W50 paper rings with allergen 01 x 10 3.20 32.00Forsythia

EP W051-0110 22711 W51 paper rings with allergen 01 x 10 3.20 32.00Aster

EP W052-0110 22873 W52 paper rings with allergen 01 x 10 3.20 32.00Willow herb

EP W053-0110 22876 W53 paper rings with allergen 01 x 10 3.20 32.00Heather

EP W054-0110 22883 W54 paper rings with allergen 01 x 10 3.20 32.00Coltsfoot

EP W100-0110 22515 W100 paper rings with allergen 01 x 10 3.20 32.00Sorrel, red

EP W101-0110 22516 W101 paper rings with allergen 01 x 10 3.20 32.00Spiny pigweed

EP W102-0110 22517 W102 paper rings with allergen 01 x 10 3.20 32.00Careless weed

EP W103-0110 22518 W103 paper rings with allergen 01 x 10 3.20 32.00Nettle

EP WD01-0110 22534 WD1 paper rings with allergen 01 x 10 3.20 32.00Sycamore Maple

EP WD02-0110 22535 WD2 paper rings with allergen 01 x 10 3.20 32.00Beech, European

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Herbal and Flower Pollen)

PreviousOrder No.

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EP WD03-0110 22536 WD3 paper rings with allergen 01 x 10 3.20 32.00Oak

EP WD04-0110 22537 WD4 paper rings with allergen 01 x 10 3.20 32.00Ash

EP WD05-0110 22675 WD5 paper rings with allergen 01 x 10 3.20 32.00Spruce, European

EP WD06-0110 22539 WD6 paper rings with allergen 01 x 10 3.20 32.00Pine

EP WD07-0110 22540 WD7 paper rings with allergen 01 x 10 3.20 32.00Limba (Afara)

EP WD08-0110 22541 WD8 paper rings with allergen 01 x 10 3.20 32.00Makore

EP WD09-0110 22542 WD9 paper rings with allergen 01 x 10 3.20 32.00Mahogany, African

EP WD12-0110 22543 WD12 paper rings with allergen 01 x 10 3.20 32.00Ramin

EP WD14-0110 22677 WD14 paper rings with allergen 01 x 10 3.20 32.00Fir

EP WD15-0110 22545 WD15 paper rings with allergen 01 x 10 3.20 32.00Teak

EP WD16-0110 22546 WD16 paper rings with allergen 01 x 10 3.20 32.00Afzelia

EP WD18-0110 22547 WD18 paper rings with allergen 01 x 10 3.20 32.00Cherry wood

EP WD19-0110 22548 WD19 paper rings with allergen 01 x 10 3.20 32.00Meranti (Red Lauan)

EP WD21-0110 22676 WD21 paper rings with allergen 01 x 10 3.20 32.00Acacia

EP WD22-0110 22678 WD22 paper rings with allergen 01 x 10 3.20 32.00Sapeli

EP WD23-0110 22863 WD23 paper rings with allergen 01 x 10 3.20 32.00Poplar wood

EP WD24-0110 22862 WD24 paper rings with allergen 01 x 10 3.20 32.00Lime wood

EP WD25-0110 22861 WD25 paper rings with allergen 01 x 10 3.20 32.00Red Cedar

EP WS01-0125 22167 WS1 paper rings with 01 x 25 3.20 80.00Weeds I allergen mixture

(W1, W6, W9, W10, W11)

EP WS13-0125 22168 WS13 paper rings with 01 x 25 3.20 80.00Weeds II allergen mixture

(W06, W09, W10, W12)

EP WS14-0110 22965 WS14 paper rings with 01 x 10 3.20 32.00Flowers I allergen mixture

(W30, W25, W33, W40)

EP WS15-0110 22973 WS15 paper rings with 01 x 10 3.20 32.00Flowers II allergen mixture

(W51, W22, W23, W7)

EP WS16-0110 22695 WS16 paper rings with 01 x 10 3.20 32.00Weeds III allergen mixture

(W1, W6, W7, W8, W12)

EP WS17-0110 22699 WS17 paper rings with 01 x 10 3.20 32.00Weeds IV allergen mixture

(W9, W10, W11, W100)

Price (€)

per Package

Antibodies

of Class IgE against

Substrate FormatOrder No. Price (€)

per Ring

Allercoat™ 6 System: Allergen Rings (Herbal and Flower Pollen)

PreviousOrder No.

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Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

FA 1010-1003 thyroid gland thyroid gland, monkey 10 x 03 (test system) 4.80 144.00FA 1010-1005 (MAb + TAb) unfixed 10 x 05 (test system) 4.60 230.00FA 1010-1010 10 x 10 (test system) 4.10 410.00FA 1010-2005 20 x 05 (test system) 4.40 440.00FB 1010-1003 10 x 03 (single slides) 3.60 108.00FB 1010-1005 10 x 05 (single slides) 3.50 175.00FB 1010-1010 10 x 10 (single slides) 3.10 310.00FB 1010-2005 20 x 05 (single slides) 3.30 330.00

FA 1010-1003-1 thyroid gland (MAb + TAb) thyroid gland monkey 10 x 03 (test system) 5.50 165.00FA 1010-1005-1 mitochondria (AMA) kidney rat 10 x 05 (test system) 5.30 265.00FA 1010-1010-1 (2 BIOCHIPs per field) 10 x 10 (test system) 4.70 470.00FA 1010-2005-1 20 x 05 (test system) 5.00 500.00FB 1010-1003-1 10 x 03 (single slides) 4.10 123.00FB 1010-1005-1 10 x 05 (single slides) 4.00 200.00FB 1010-1010-1 10 x 10 (single slides) 3.60 360.00FB 1010-2005-1 20 x 05 (single slides) 3.80 380.00

FA 1010-1005-2 “Polyendocrinopathy Mosaic” 6 BIOCHIPs per field: 10 x 05 (test system) 20.40 1,020.00FA 1010-2005-2 thyroid gland (MAb + TAb) thyroid gland monkey 20 x 05 (test system) 19.40 1,940.00FB 1010-1005-2 pancreas islets pancreas monkey 10 x 05 (single slides) 15.30 765.00FB 1010-2005-2 adrenal cortex adrenal gland monkey 20 x 05 (single slides) 14.60 1,460.00

ovarial antigens ovary monkeyLeydig cells testis monkey

parietal cells (PCA) stomach monkey

FA 1010-1003-3 “EUROPLUS” 2 BIOCHIPs per field: 10 x 03 (test system) 6.30 189.00FA 1010-1005-3 thyroid gland (MAb + TAb) thyroid gland monkey 10 x 05 (test system) 6.10 305.00FA 1010-1010-3 thyroglobulin (TG) TG BIOCHIPs human 10 x 10 (test system) 5.50 550.00FA 1010-2005-3 20 x 05 (test system) 5.80 580.00FB 1010-1003-3 10 x 03 (single slides) 4.70 141.00FB 1010-1005-3 10 x 05 (single slides) 4.60 230.00FB 1010-1010-3 10 x 10 (single slides) 4.10 410.00FB 1010-2005-3 20 x 05 (single slides) 4.30 430.00

FA 1020-1003 pancreas islets pancreas monkey 10 x 03 (test system) 4.80 144.00FA 1020-1005 + Crohn’s disease autoantigen 10 x 05 (test system) 4.60 230.00FA 1020-1010 10 x 10 (test system) 4.10 410.00FA 1020-2005 20 x 05 (test system) 4.40 440.00FB 1020-1003 10 x 03 (single slides) 3.60 108.00FB 1020-1005 10 x 05 (single slides) 3.50 175.00FB 1020-1010 10 x 10 (single slides) 3.10 310.00FB 1020-2005 20 x 05 (single slides) 3.30 330.00

FA 1020-1003-3 pancreas islets, GAD pancreas monkey 10 x 03 (test system) 7.60 228.00FA 1020-1005-3 brain: grey and white matter, cerebellum monkey 10 x 05 (test system) 7.30 365.00FA 1020-1010-3 Purkinje cell cytoplasm (Yo), (2 BIOCHIPs per field) 10 x 10 (test system) 6.60 660.00FA 1020-2005-3 Hu and Ri 20 x 05 (test system) 6.90 690.00FB 1020-1003-3 10 x 03 (single slides) 5.70 171.00FB 1020-1005-3 10 x 05 (single slides) 5.50 275.00FB 1020-1010-3 10 x 10 (single slides) 4.90 490.00FB 1020-2005-3 20 x 05 (single slides) 5.20 520.00

FA 1040-1003 parathyroid gland parathyroid monkey 10 x 03 (test system) 9.30 279.00FA 1040-1005 gland 10 x 05 (test system) 9.00 450.00FA 1040-1010 10 x 10 (test system) 8.10 810.00FA 1040-2005 20 x 05 (test system) 8.50 850.00FB 1040-1003 10 x 03 (single slides) 7.00 210.00FB 1040-1005 10 x 05 (single slides) 6.70 335.00FB 1040-1010 10 x 10 (single slides) 6.10 610.00FB 1040-2005 20 x 05 (single slides) 6.40 640.00

FA 1050-1003 adrenal cortex adrenal gland monkey 10 x 03 (test system) 4.80 144.00FA 1050-1005 10 x 05 (test system) 4.60 230.00FA 1050-1010 10 x 10 (test system) 4.10 410.00FA 1050-2005 20 x 05 (test system) 4.40 440.00FB 1050-1003 10 x 03 (single slides) 3.60 108.00FB 1050-1005 10 x 05 (single slides) 3.50 175.00FB 1050-1010 10 x 10 (single slides) 3.10 310.00FB 1050-2005 20 x 05 (single slides) 3.30 330.00

FA 1060-1003 ovarial antigens ovary monkey 10 x 03 (test system) 9.30 279.00FA 1060-1005 10 x 05 (test system) 9.00 450.00FA 1060-1010 10 x 10 (test system) 8.10 810.00FA 1060-2005 20 x 05 (test system) 8.50 850.00FB 1060-1003 10 x 03 (single slides) 7.00 210.00FB 1060-1005 10 x 05 (single slides) 6.70 335.00FB 1060-1010 10 x 10 (single slides) 6.10 610.00FB 1060-2005 20 x 05 (single slides) 6.40 640.00

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*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

FA 1070-1003 * placental antigens placenta monkey 10 x 03 (test system) 4.80 144.00FA 1070-1005 * 10 x 05 (test system) 4.60 230.00FA 1070-1010 * 10 x 10 (test system) 4.10 410.00FA 1070-2005 * 20 x 05 (test system) 4.40 440.00FB 1070-1003 * 10 x 03 (single slides) 3.60 108.00FB 1070-1005 * 10 x 05 (single slides) 3.50 175.00FB 1070-1010 * 10 x 10 (single slides) 3.10 310.00FB 1070-2005 * 20 x 05 (single slides) 3.30 330.00

FA 1080-1003 Leydig cells testis monkey 10 x 03 (test system) 4.80 144.00FA 1080-1005 10 x 05 (test system) 4.60 230.00FA 1080-1010 10 x 10 (test system) 4.10 410.00FA 1080-2005 20 x 05 (test system) 4.40 440.00FB 1080-1003 10 x 03 (single slides) 3.60 108.00FB 1080-1005 10 x 05 (single slides) 3.50 175.00FB 1080-1010 10 x 10 (single slides) 3.10 310.00FB 1080-2005 20 x 05 (single slides) 3.30 330.00

FA 1086-1003 spermatozoa smear human 10 x 03 (test system) 4.80 144.00FA 1086-1005 10 x 05 (test system) 4.60 230.00FA 1086-1010 10 x 10 (test system) 4.10 410.00FA 1086-2005 20 x 05 (test system) 4.40 440.00FB 1086-1003 10 x 03 (single slides) 3.60 108.00FB 1086-1005 10 x 05 (single slides) 3.50 175.00FB 1086-1010 10 x 10 (single slides) 3.10 310.00FB 1086-2005 20 x 05 (single slides) 3.30 330.00

FA 1090-1003 pituitary gland antigens pituitary gland monkey 10 x 03 (test system) 9.30 279.00FA 1090-1005 (anterior + posterior lobe) 10 x 05 (test system) 9.00 450.00FA 1090-2005 20 x 05 (test system) 8.50 850.00FB 1090-1003 10 x 03 (single slides) 7.00 210.00FB 1090-1005 10 x 05 (single slides) 6.70 335.00FB 1090-2005 20 x 05 (single slides) 6.40 640.00

FA 1091-1005 pituitary gland antigens pituitary gland monkey 10 x 05 (test system) 4.60 230.00FA 1091-1010 (anterior lobe) 10 x 10 (test system) 4.10 410.00FA 1091-2005 20 x 05 (test system) 4.40 440.00FB 1091-1005 10 x 05 (single slides) 3.50 175.00FB 1091-1010 10 x 10 (single slides) 3.10 310.00FB 1091-2005 20 x 05 (single slides) 3.30 330.00

FA 1100-1005 * hypothalamus antigens nucleus supraopticus/ monkey 10 x 05 (test system) 9.00 450.00FA 1100-1010 * paraventricularis 10 x 10 (test system) 8.10 810.00FA 1100-2005 * 20 x 05 (test system) 8.50 850.00FB 1100-1005 * 10 x 05 (single slides) 6.70 335.00FB 1100-1010 * 10 x 10 (single slides) 6.10 610.00FB 1100-2005 * 20 x 05 (single slides) 6.40 640.00

FA 1111-1003 brain: grey and white matter, cerebellum monkey 10 x 03 (test system) 4.80 144.00FA 1111-1005 Purkinje cell cytoplasm (Yo), 10 x 05 (test system) 4.60 230.00FA 1111-1010 Hu and Ri antigen 10 x 10 (test system) 4.10 410.00FA 1111-2005 CV2, Ma, amphiphysin 20 x 05 (test system) 4.40 440.00FB 1111-1003 10 x 03 (single slides) 3.60 108.00FB 1111-1005 10 x 05 (single slides) 3.50 175.00FB 1111-1010 10 x 10 (single slides) 3.10 310.00FB 1111-2005 20 x 05 (single slides) 3.30 330.00

FA 1111-1003-1 “Neurology Mosaic 1” 3 BIOCHIPs per field: 10 x 03 (test system) 9.90 297.00FA 1111-1005-1 Yo, Hu, Ri, CV2, Ma, amphiphysin cerebellum monkey 10 x 05 (test system) 9.60 480.00FA 1111-2005-1 medullated nerves nerves monkey 20 x 05 (test system) 9.10 910.00FB 1111-1003-1 non-medullated nerves intestinal tissue monkey 10 x 03 (single slides) 7.50 225.00FB 1111-1005-1 10 x 05 (single slides) 7.20 360.00FB 1111-2005-1 20 x 05 (single slides) 6.80 680.00

FA 1111-1003-2 “Neurology Mosaic 2” 2 BIOCHIPs per field: 10 x 03 (test system) 7.60 228.00FA 1111-1005-2 Yo, Hu, Ri, CV2, Ma, amphiphysin cerebellum monkey 10 x 05 (test system) 7.30 365.00FA 1111-1010-2 medullated nerves nerves monkey 10 x 10 (test system) 6.60 660.00FA 1111-2005-2 20 x 05 (test system) 6.90 690.00FB 1111-1003-2 10 x 03 (single slides) 5.70 171.00FB 1111-1005-2 10 x 05 (single slides) 5.50 275.00FB 1111-1010-2 10 x 10 (single slides) 4.90 490.00FB 1111-2005-2 20 x 05 (single slides) 5.20 520.00

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Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

FA 1111-1005-8 “Neurology Mosaic 8” 4 BIOCHIPs per field 10 x 05 (test system) 12.30 615.00FA 1111-1010-8 Yo, Hu, Ri, CV2, Ma, amphiphysin cerebellum monkey 10 x 10 (test system) 11.10 1,110.00FA 1111-2005-8 medullated nerves nerves monkey 20 x 05 (test system) 11.70 1,170.00FB 1111-1005-8 non-medullated nerves intestinal tissue monkey 10 x 05 (single slides) 9.20 460.00FB 1111-1010-8 pancreas islets pancreas monkey 10 x 10 (single slides) 8.30 830.00FB 1111-2005-8 20 x 05 (single slides) 8.80 880.00

FA 1111-1005-13 “Neurology Mosaic 13” 3 BIOCHIPs per field: 10 x 05 (test system) 7.80 390.00FA 1111-1010-13 Yo, Hu, Ri, CV2, Ma, amphiphysin cerebellum monkey 10 x 10 (test system) 7.00 700.00FA 1111-2005-13 non-medullated nerves intestinal tissue monkey 20 x 05 (test system) 7.40 740.00FA 1111-2010-13 cell nuclei (ANA) HEp-2-cells human 20 x 10 (test system) 6.60 1,320.00FB 1111-1005-13 10 x 05 (single slides) 5.80 290.00FB 1111-1010-13 10 x 10 (single slides) 5.30 530.00FB 1111-2005-13 20 x 05 (single slides) 5.50 550.00FB 1111-2010-13 20 x 10 (single slides) 5.00 1,000.00

FA 1111-1003-14 Yo, Hu, Ri, CV2, Ma, amphiphysin cerebellum monkey 10 x 03 (test system) 7.60 228.00FA 1111-1005-14 non-medullated nerves intestinal tissue monkey 10 x 05 (test system) 7.30 365.00FA 1111-1010-14 (2 BIOCHIPs per field) 10 x 10 (test system) 6.60 660.00FA 1111-2005-14 20 x 05 (test system) 6.90 690.00FB 1111-1003-14 10 x 03 (single slides) 5.70 171.00FB 1111-1005-14 10 x 05 (single slides) 5.50 275.00FB 1111-1010-14 10 x 10 (single slides) 4.90 490.00FB 1111-2005-14 20 x 05 (single slides) 5.20 520.00

FA 1120-1005 medullated nerves nerves (nervus suralis) monkey 10 x 05 (test system) 4.60 230.00FA 1120-1010 10 x 10 (test system) 4.10 410.00FA 1120-2005 20 x 05 (test system) 4.40 440.00FB 1120-1005 10 x 05 (single slides) 3.50 175.00FB 1120-1010 10 x 10 (single slides) 3.10 310.00FB 1120-2005 20 x 05 (single slides) 3.30 330.00

FA 1129-1005 non-medullated nerves intestinal tissue monkey 10 x 05 (test system) 4.60 230.00FA 1129-1010 10 x 10 (test system) 4.10 410.00FA 1129-2005 20 x 05 (test system) 4.40 440.00FB 1129-1005 10 x 05 (single slides) 3.50 175.00FB 1129-1010 10 x 10 (single slides) 3.10 310.00FB 1129-2005 20 x 05 (single slides) 3.30 330.00

FA 1170-1005 eye antigens eye monkey 10 x 05 (test system) 9.00 450.00FA 1170-2005 20 x 05 (test system) 8.50 850.00FB 1170-1005 10 x 05 (single slides) 6.70 335.00FB 1170-2005 20 x 05 (single slides) 6.40 640.00

FA 1172-1005 retina eye monkey 10 x 05 (test system) 4.60 230.00FA 1172-2005 20 x 05 (test system) 4.40 440.00FB 1172-1005 10 x 05 (single slides) 3.50 175.00FB 1172-2005 20 x 05 (single slides) 3.30 330.00

FA 1200-1003 cytoplasm of granulocytes (cANCA, granulocytes, human 10 x 03 (test system) 3.70 111.00FA 1200-1005 pANCA), nuclei of granuloc. (GS-ANA) ethanol-fixed (blood group 0) 10 x 05 (test system) 3.60 180.00FA 1200-1010 10 x 10 (test system) 3.20 320.00FA 1200-2005 20 x 05 (test system) 3.40 340.00FB 1200-1003 10 x 03 (single slides) 2.80 84.00FB 1200-1005 10 x 05 (single slides) 2.70 135.00FB 1200-1010 10 x 10 (single slides) 2.40 240.00FB 1200-2005 20 x 05 (single slides) 2.60 260.00

FA 1201-1003 granulocytes granulocytes, human 10 x 03 (test system) 3.70 111.00FA 1201-1005 (cANCA, pANCA) formaldehyde-fixed (blood group 0) 10 x 05 (test system) 3.60 180.00FA 1201-1010 10 x 10 (test system) 3.20 320.00FA 1201-2005 20 x 05 (test system) 3.40 340.00FB 1201-1003 10 x 03 (single slides) 2.80 84.00FB 1201-1005 10 x 05 (single slides) 2.70 135.00FB 1201-1010 10 x 10 (single slides) 2.40 240.00FB 1201-2005 20 x 05 (single slides) 2.60 260.00

FA 1201-1003-1 “Granulocyte Mosaic 1” 2 BIOCHIPs per field: 10 x 03 (test system) 4.20 126.00FA 1201-1005-1 cANCA, pANCA, GS-ANA, granulocytes (EOH) human 10 x 05 (test system) 4.00 200.00FA 1201-1010-1 liver antigens, ANA liver monkey 10 x 10 (test system) 3.60 360.00FA 1201-2005-1 20 x 05 (test system) 3.80 380.00FA 1201-2010-1 20 x 10 (test system) 3.50 700.00FB 1201-1003-1 10 x 03 (single slides) 3.20 96.00FB 1201-1005-1 10 x 05 (single slides) 3.10 155.00FB 1201-1010-1 10 x 10 (single slides) 2.70 270.00FB 1201-2005-1 20 x 05 (single slides) 2.90 290.00FB 1201-2010-1 20 x 10 (single slides) 2.60 520.00

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Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

FA 1201-1003-2 “Granulocyte Mosaic 2” 2 BIOCHIPs per field: 10 x 03 (test system) 5.90 177.00FA 1201-1005-2 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 05 (test system) 5.70 285.00FA 1201-1010-2 cANCA, pANCA granulocytes (HCHO) human 10 x 10 (test system) 5.10 510.00FA 1201-2005-2 20 x 05 (test system) 5.40 540.00FA 1201-2010-2 20 x 10 (test system) 4.80 960.00FB 1201-1003-2 10 x 03 (single slides) 4.40 132.00FB 1201-1005-2 10 x 05 (single slides) 4.30 215.00FB 1201-1010-2 10 x 10 (single slides) 3.80 380.00FB 1201-2005-2 20 x 05 (single slides) 4.10 410.00FB 1201-2010-2 20 x 10 (single slides) 3.70 740.00

FA 1201-1003-3 “Granulocyte Mosaic 3” 4 BIOCHIPs per field: 10 x 03 (test system) 6.80 204.00FA 1201-1005-3 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 05 (test system) 6.50 325.00FA 1201-1010-3 cANCA, pANCA granulocytes (HCHO) human 10 x 10 (test system) 5.90 590.00FA 1201-2005-3 cell nuclei (ANA) HEp-2 cells human 20 x 05 (test system) 6.20 620.00FA 1201-2010-3 liver antigens, ANA liver monkey 20 x 10 (test system) 5.60 1,120.00FB 1201-1003-3 10 x 03 (single slides) 5.10 153.00FB 1201-1005-3 10 x 05 (single slides) 4.90 245.00FB 1201-1010-3 10 x 10 (single slides) 4.40 440.00FB 1201-2005-3 20 x 05 (single slides) 4.70 470.00FB 1201-2010-3 20 x 10 (single slides) 4.20 840.00

FA 1201-1003-4 “Granulocyte Mosaic 4” 3 BIOCHIPs per field: 10 x 03 (test system) 6.60 198.00FA 1201-1005-4 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 05 (test system) 6.30 315.00FA 1201-1010-4 cANCA, pANCA granulocytes (HCHO) human 10 x 10 (test system) 5.70 570.00FA 1201-2005-4 cell nuclei (ANA) HEp-2 cells human 20 x 05 (test system) 6.00 600.00FB 1201-1003-4 10 x 03 (single slides) 4.90 147.00FB 1201-1005-4 10 x 05 (single slides) 4.70 235.00FB 1201-1010-4 10 x 10 (single slides) 4.30 430.00FB 1201-2005-4 20 x 05 (single slides) 4.50 450.00

FA 1201-1003-5 “Granulocyte Mosaic 5” 4 BIOCHIPs per field: 10 x 03 (test system) 7.90 237.00FA 1201-1005-5 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 05 (test system) 7.60 380.00FA 1201-1010-5 cANCA, pANCA granulocytes (HCHO) human 10 x 10 (test system) 6.80 680.00FA 1201-2005-5 cANCA, pANCA granulocytes (MOH) human 20 x 05 (test system) 7.20 720.00FB 1201-1003-5 liver antigens, ANA liver monkey 10 x 03 (single slides) 5.90 177.00FB 1201-1005-5 10 x 05 (single slides) 5.70 285.00FB 1201-1010-5 10 x 10 (single slides) 5.10 510.00FB 1201-2005-5 20 x 05 (single slides) 5.40 540.00

FA 1201-1005-7 pANCA, cANCA granulocytes (EOH) human 10 x 05 (test system) 4.40 220.00FA 1201-1010-7 cell nuclei (ANA) HEp-2 cells human 10 x 10 (test system) 4.00 400.00FA 1201-2005-7 (2 BIOCHIPs per field) 20 x 05 (test system) 4.20 420.00FB 1201-1005-7 10 x 05 (single slides) 3.40 170.00FB 1201-1010-7 10 x 10 (single slides) 3.00 300.00FB 1201-2005-7 20 x 05 (single slides) 3.20 320.00

FA 1201-1003-8 “Granulocyte Mosaic 8” 3 BIOCHIPs per field: 10 x 03 (test system) 6.20 186.00FA 1201-1005-8 cANCA, pANCA granulocytes (EOH) human 10 x 05 (test system) 6.00 300.00FA 1201-1010-8 cANCA, pANCA granulocytes (HCHO) human 10 x 10 (test system) 5.40 540.00FA 1201-2005-8 liver antigens, ANA liver monkey 20 x 05 (test system) 5.70 570.00FA 1201-2010-8 20 x 10 (test system) 5.10 1,020.00FB 1201-1003-8 10 x 03 (single slides) 4.70 141.00FB 1201-1005-8 10 x 05 (single slides) 4.50 225.00FB 1201-1010-8 10 x 10 (single slides) 4.00 400.00FB 1201-2005-8 20 x 05 (single slides) 4.30 430.00FB 1201-2010-8 20 x 10 (single slides) 3.80 760.00

FA 1201-1005-13 “Granulocyte Mosaic 13” 3 BIOCHIPs per field: 10 x 05 (test system) 6.50 325.00FA 1201-1010-13 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 10 (test system) 5.90 590.00FA 1201-2005-13 cell nuclei (ANA), cANCA, pANCA HEp-2 + granulocytes (EOH) human 20 x 05 (test system) 6.20 620.00FB 1201-1005-13 cANCA, pANCA granulocytes (HCHO) human 10 x 05 (single slides) 4.90 245.00FB 1201-1010-13 10 x 10 (single slides) 4.50 450.00FB 1201-2005-13 20 x 05 (single slides) 4.70 470.00

FA 1201-1003-15 “Granulocyte Mosaic 15” 2 BIOCHIPs per field: 10 x 03 (test system) 4.20 126.00FA 1201-1005-15 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 05 (test system) 4.00 200.00FA 1201-1010-15 cell nuclei (ANA), cANCA, pANCA HEp-2 + granulocytes (EOH) human 10 x 10 (test system) 3.60 360.00FA 1201-2005-15 20 x 05 (test system) 3.80 380.00FA 1201-2010-15 20 x 10 (test system) 3.50 700.00FB 1201-1003-15 10 x 03 (single slides) 3.20 96.00FB 1201-1005-15 10 x 05 (single slides) 3.10 155.00FB 1201-1010-15 10 x 10 (single slides) 2.70 270.00FB 1201-2005-15 20 x 05 (single slides) 2.90 290.00FB 1201-2010-15 20 x 10 (single slides) 2.60 520.00

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Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

FA 1201-1003-16 “Granulocyte Mosaic 16” 4 BIOCHIPs per field: 10 x 03 (test system) 6.80 204.00FA 1201-1005-16 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 05 (test system) 6.50 325.00FA 1201-1010-16 cANCA, pANCA granulocytes (HCHO) human 10 x 10 (test system) 5.90 590.00FA 1201-2005-16 cell nuclei (ANA) HEp-2 cells human 20 x 05 (test system) 6.20 620.00FA 1201-2010-16 cell nuclei (ANA), cANCA, pANCA HEp-2 + granulocytes (EOH) human 20 x 10 (test system) 5.60 1,120.00FB 1201-1003-16 10 x 03 (single slides) 5.10 153.00FB 1201-1005-16 10 x 05 (single slides) 4.90 245.00FB 1201-1010-16 10 x 10 (single slides) 4.40 440.00FB 1201-2005-16 20 x 05 (single slides) 4.70 470.00FB 1201-2010-16 20 x 10 (single slides) 4.20 840.00

FA 1201-1003-17 “Granulocyte Mosaic 17” 4 BIOCHIPs per field: 10 x 03 (test system) 7.90 237.00FA 1201-1005-17 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 05 (test system) 7.60 380.00FA 1201-1010-17 cANCA, pANCA granulocytes (HCHO) human 10 x 10 (test system) 6.80 680.00FA 1201-2005-17 cANCA, pANCA granulocytes (MOH) human 20 x 05 (test system) 7.20 720.00FB 1201-1003-17 cell nuclei (ANA), cANCA, pANCA HEp-2 + granulocytes (EOH) human 10 x 03 (single slides) 5.90 177.00FB 1201-1005-17 10 x 05 (single slides) 5.70 285.00FB 1201-1010-17 10 x 10 (single slides) 5.10 510.00FB 1201-2005-17 20 x 05 (single slides) 5.40 540.00

FA 1201-1005-20 “EUROPLUS Granulocyte Mosaic 20” 3 BIOCHIPs per field: 10 x 05 (test system) 11.70 585.00FA 1201-1010-20 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 10 (test system) 10.60 1,060.00FA 1201-2005-20 pANCA: myeloperoxidase (MPO) MPO BIOCHIPs 20 x 05 (test system) 11.20 1,120.00FB 1201-1005-20 cANCA: proteinase 3 (PR3) PR3 BIOCHIPs 10 x 05 (single slides) 8.80 440.00FB 1201-1010-20 10 x 10 (single slides) 8.00 800.00FB 1201-2005-20 20 x 05 (single slides) 8.40 840.00

FA 1201-1005-22 “EUROPLUS Granulocyte Mosaic 22” 4 BIOCHIPs per field: 10 x 05 (test system) 13.50 675.00FA 1201-1010-22 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 10 (test system) 12.20 1,220.00FA 1201-2005-22 cANCA, pANCA granulocytes (HCHO) human 20 x 05 (test system) 12.90 1,290.00FB 1201-1005-22 pANCA: myeloperoxidase (MPO) MPO BIOCHIPs 10 x 05 (single slides) 10.20 510.00FB 1201-1010-22 cANCA: proteinase 3 (PR3) PR3 BIOCHIPs 10 x 10 (single slides) 9.20 920.00FB 1201-2005-22 20 x 05 (single slides) 9.70 970.00

FA 1201-1005-23 “EUROPLUS Granulocyte Mosaic 23” 6 BIOCHIPs per field: 10 x 05 (test system) 14.80 740.00FA 1201-1010-23 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 10 (test system) 13.40 1,340.00FA 1201-2005-23 cANCA, pANCA granulocytes (HCHO) human 20 x 05 (test system) 14.10 1,410.00FB 1201-1005-23 cell nuclei (ANA) HEp-2 cells human 10 x 05 (single slides) 11.10 555.00FB 1201-1010-23 liver antigens, ANA liver monkey 10 x 10 (single slides) 10.10 1,010.00FB 1201-2005-23 pANCA: myeloperoxidase (MPO) MPO BIOCHIPs 20 x 05 (single slides) 10.60 1,060.00

cANCA: proteinase 3 (PR3) PR3 BIOCHIPs

FA 1201-1005-24 “EUROPLUS Granulocyte Mosaic 24” 6 BIOCHIPs per field: 10 x 05 (test system) 14.80 740.00FA 1201-1010-24 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 10 (test system) 13.40 1,340.00FA 1201-2005-24 cANCA, pANCA granulocytes (HCHO) human 20 x 05 (test system) 14.10 1,410.00FB 1201-1005-24 cell nuclei (ANA) HEp-2 cells human 10 x 05 (single slides) 11.10 555.00FB 1201-1010-24 cell nuclei (ANA), cANCA, pANCA HEp-2 + granulocytes (EOH) human 10 x 10 (single slides) 10.10 1,010.00FB 1201-2005-24 pANCA: myeloperoxidase (MPO) MPO BIOCHIPs 20 x 05 (single slides) 10.60 1,060.00

cANCA: proteinase 3 (PR3) PR3 BIOCHIPs

FA 1202-1005 cytoplasm of granulocytes (cANCA, granulocytes, human 10 x 05 (test system) 3.60 180.00FA 1202-1010 pANCA), nuclei of granuloc. (GS-ANA) methanol-fixed (blood group 0) 10 x 10 (test system) 3.20 320.00FA 1202-2005 20 x 05 (test system) 3.40 340.00FB 1202-1005 10 x 05 (single slides) 2.70 135.00FB 1202-1010 10 x 10 (single slides) 2.40 240.00FB 1202-2005 20 x 05 (single slides) 2.60 260.00

FA 1221-1005 lymphocyte antigens lymphocytes human 10 x 05 (test system) 5.10 255.00FA 1221-1010 (blood group 0) 10 x 10 (test system) 4.60 460.00FA 1221-2005 20 x 05 (test system) 4.80 480.00FB 1221-1005 10 x 05 (single slides) 3.80 190.00FB 1221-1010 10 x 10 (single slides) 3.50 350.00FB 1221-2005 20 x 05 (single slides) 3.70 370.00

FA 1230-1003 thrombocyte antigens thrombocytes human 10 x 03 (test system) 5.30 159.00FA 1230-1005 (blood group 0) 10 x 05 (test system) 5.10 255.00FA 1230-1010 10 x 10 (test system) 4.60 460.00FA 1230-2005 20 x 05 (test system) 4.80 480.00FB 1230-1003 10 x 03 (single slides) 4.00 120.00FB 1230-1005 10 x 05 (single slides) 3.80 190.00FB 1230-1010 10 x 10 (single slides) 3.50 350.00FB 1230-2005 20 x 05 (single slides) 3.70 370.00

FA 1250-1003 renal glomeruli (GBM) kidney monkey 10 x 03 (test system) 4.80 144.00FA 1250-1005 + renal tubuli 10 x 05 (test system) 4.60 230.00FA 1250-1010 10 x 10 (test system) 4.10 410.00FA 1250-2005 20 x 05 (test system) 4.40 440.00FB 1250-1003 10 x 03 (single slides) 3.60 108.00FB 1250-1005 10 x 05 (single slides) 3.50 175.00FB 1250-1010 10 x 10 (single slides) 3.10 310.00FB 1250-2005 20 x 05 (single slides) 3.30 330.00

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Price (€)

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Antibodies

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Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

FA 1270-1003 * lung alveoli lung monkey 10 x 03 (test system) 4.80 144.00FA 1270-1005 * 10 x 05 (test system) 4.60 230.00FA 1270-1010 * 10 x 10 (test system) 4.10 410.00FA 1270-2005 * 20 x 05 (test system) 4.40 440.00FB 1270-1003 * 10 x 03 (single slides) 3.60 108.00FB 1270-1005 * 10 x 05 (single slides) 3.50 175.00FB 1270-1010 * 10 x 10 (single slides) 3.10 310.00FB 1270-2005 * 20 x 05 (single slides) 3.30 330.00

FA 1271-1005-1 renal glomeruli (GBM) kidney monkey 10 x 05 (test system) 7.30 365.00FA 1271-1010-1 lung alveoli lung monkey 10 x 10 (test system) 6.60 660.00FA 1271-2005-1 (Goodpasture syndrome) (2 BIOCHIPs per field) 20 x 05 (test system) 6.90 690.00FB 1271-1005-1 10 x 05 (single slides) 5.50 275.00FB 1271-1010-1 10 x 10 (single slides) 4.90 490.00FB 1271-2005-1 20 x 05 (single slides) 5.20 520.00

FA 1300-1003 liver-specific liver monkey 10 x 03 (test system) 4.80 144.00FA 1300-1005 antigens 10 x 05 (test system) 4.60 230.00FA 1300-1010 10 x 10 (test system) 4.10 410.00FA 1300-2005 20 x 05 (test system) 4.40 440.00FB 1300-1003 10 x 03 (single slides) 3.60 108.00FB 1300-1005 10 x 05 (single slides) 3.50 175.00FB 1300-1010 10 x 10 (single slides) 3.10 310.00FB 1300-2005 20 x 05 (single slides) 3.30 330.00

FA 1300-1003-1 “Liver Mosaic 1” 2 BIOCHIPs per field: 10 x 03 (test system) 3.30 99.00FA 1300-1005-1 liver-kidney microsomes (LKM) liver rat 10 x 05 (test system) 3.20 160.00FA 1300-1010-1 LKM, mitochondria (AMA) kidney rat 10 x 10 (test system) 2.90 290.00FA 1300-2005-1 20 x 05 (test system) 3.10 310.00FB 1300-1003-1 10 x 03 (single slides) 2.50 75.00FB 1300-1005-1 10 x 05 (single slides) 2.40 120.00FB 1300-1010-1 10 x 10 (single slides) 2.20 220.00FB 1300-2005-1 20 x 05 (single slides) 2.30 230.00

FA 1300-1003-2 “Liver Mosaic 2” 6 BIOCHIPs per field: 10 x 03 (test system) 7.20 216.00FA 1300-1005-2 liver antigens, cell nuclei (ANA) liver monkey 10 x 05 (test system) 7.00 350.00FA 1300-2005-2 AMA M7, heart antigens heart monkey 20 x 05 (test system) 6.60 660.00FB 1300-1003-2 cell nuclei (ANA) HEp-2 cells human 10 x 03 (single slides) 5.50 165.00FB 1300-1005-2 liver antigens, LKM, ANA liver rat 10 x 05 (single slides) 5.30 265.00FB 1300-2005-2 mitochondria (AMA), LKM kidney rat 20 x 05 (single slides) 5.00 500.00

smooth muscles (ASMA) stomach rat

FA 1300-1003-3 “Liver Mosaic 3” 6 BIOCHIPs per field: 10 x 03 (test system) 8.90 267.00FA 1300-1005-3 liver antigens, cell nuclei (ANA) liver monkey 10 x 05 (test system) 8.50 425.00FA 1300-2005-3 skeletal muscle musculus iliopsoas monkey 20 x 05 (test system) 8.10 810.00FB 1300-1003-3 cell nuclei (ANA) HEp-2 cells human 10 x 03 (single slides) 6.70 201.00FB 1300-1005-3 liver antigens, LKM, cell nuclei (ANA) liver rat 10 x 05 (single slides) 6.40 320.00FB 1300-2005-3 mitochondria (AMA), LKM kidney rat 20 x 05 (single slides) 6.10 610.00

smooth muscles (ASMA) stomach rat

FA 1300-1005-6 “Liver Mosaic 6” 6 BIOCHIPs per field: 10 x 05 (test system) 10.20 510.00FA 1300-2005-6 liver antigens, cell nuclei (ANA) liver monkey 20 x 05 (test system) 9.70 970.00FB 1300-1005-6 AMA M7, heart antigens heart monkey 10 x 05 (single slides) 7.70 385.00FB 1300-2005-6 cell nuclei (ANA) HEp-2 cells human 20 x 05 (single slides) 7.20 720.00

liver antigens, cell nuclei (ANA) liver ratmitochondria (AMA) kidney ratparietal cells (PCA) stomach monkey

FA 1300-1005-8 “Liver Mosaic 8” 6 BIOCHIPs per field: 10 x 05 (test system) 6.90 345.00FA 1300-2005-8 liver antigens, cell nuclei (ANA) liver monkey 20 x 05 (test system) 6.50 650.00FB 1300-1005-8 F-actin, VSM47 rat 10 x 05 (single slides) 5.20 260.00FB 1300-2005-8 cell nuclei (ANA) HEp-2 cells human 20 x 05 (single slides) 4.90 490.00

liver antigens, LKM, ANA liver ratmitochondria (AMA), LKM kidney ratsmooth muscles (ASMA) stomach rat

FA 1300-1003-20 “EUROPLUS” PBC/AIH 6 BIOCHIPs per field: 10 x 03 (test system) 13.70 411.00FA 1300-1005-20 liver antigens, cell nuclei (ANA) liver monkey 10 x 05 (test system) 13.20 660.00FA 1300-2005-20 cell nuclei (ANA) HEp-2 cells human 20 x 05 (test system) 12.60 1,260.00FB 1300-1003-20 liver antigens, LKM, ANA liver rat 10 x 03 (single slides) 10.30 309.00FB 1300-1005-20 mitochondria (AMA), LKM kidney rat 10 x 05 (single slides) 10.00 500.00FB 1300-2005-20 smooth muscles (ASMA) stomach rat 20 x 05 (single slides) 9.40 940.00

AMA M2, Sp100, LC-1, SLA/LP AMA-M2, Sp100, LC-1, SLA/LP-BIOCHIP

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Price (€)

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Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

FA 1360-1003 parietal cells stomach monkey 10 x 03 (test system) 4.80 144.00FA 1360-1005 (PCA) 10 x 05 (test system) 4.60 230.00FA 1360-1010 10 x 10 (test system) 4.10 410.00FA 1360-2005 20 x 05 (test system) 4.40 440.00FB 1360-1003 10 x 03 (single slides) 3.60 108.00FB 1360-1005 10 x 05 (single slides) 3.50 175.00FB 1360-1010 10 x 10 (single slides) 3.10 310.00FB 1360-2005 20 x 05 (single slides) 3.30 330.00

FA 1360-1003-1 parietal cells (PCA) stomach monkey 10 x 03 (test system) 5.50 165.00FA 1360-1005-1 mitochondria (AMA) kidney rat 10 x 05 (test system) 5.30 265.00FA 1360-1010-1 (2 BIOCHIPs per field) 10 x 10 (test system) 4.70 470.00FA 1360-2005-1 20 x 05 (test system) 5.00 500.00FB 1360-1003-1 10 x 03 (single slides) 4.10 123.00FB 1360-1005-1 10 x 05 (single slides) 4.00 200.00FB 1360-1010-1 10 x 10 (single slides) 3.60 360.00FB 1360-2005-1 20 x 05 (single slides) 3.80 380.00

FA 1362-1003 intrinsic factor intrinsic factor BIOCHIPs 10 x 03 (test system) 5.30 159.00FA 1362-1005 10 x 05 (test system) 5.10 255.00FA 1362-1010 10 x 10 (test system) 4.60 460.00FA 1362-2005 20 x 05 (test system) 4.80 480.00FB 1362-1003 10 x 03 (single slides) 4.00 120.00FB 1362-1005 10 x 05 (single slides) 3.80 190.00FB 1362-1010 10 x 10 (single slides) 3.50 350.00FB 1362-2005 20 x 05 (single slides) 3.70 370.00

FA 1362-1003-1 “EUROPLUS” 2 BIOCHIPs per field: 10 x 03 (test system) 8.00 240.00FA 1362-1005-1 parietal cells (PCA) stomach monkey 10 x 05 (test system) 7.70 385.00FA 1362-1010-1 intrinsic factor intrinsic factor BIOCHIPs 10 x 10 (test system) 6.90 690.00FA 1362-2005-1 20 x 05 (test system) 7.40 740.00FB 1362-1003-1 10 x 03 (single slides) 6.00 180.00FB 1362-1005-1 10 x 05 (single slides) 5.80 290.00FB 1362-1010-1 10 x 10 (single slides) 5.20 520.00FB 1362-2005-1 20 x 05 (single slides) 5.50 550.00

FA 1380-1003 intestinal goblet cells intestinal tissue monkey 10 x 03 (test system) 4.80 144.00FA 1380-1005 10 x 05 (test system) 4.60 230.00FA 1380-1010 10 x 10 (test system) 4.10 410.00FA 1380-2005 20 x 05 (test system) 4.40 440.00FB 1380-1003 10 x 03 (single slides) 3.60 108.00FB 1380-1005 10 x 05 (single slides) 3.50 175.00FB 1380-1010 10 x 10 (single slides) 3.10 310.00FB 1380-2005 20 x 05 (single slides) 3.30 330.00

FA 1380-1003-1 “Mosaic Intestine/Pancreas” 2 BIOCHIPs per field: 10 x 03 (test system) 7.60 228.00FA 1380-1005-1 intestinal goblet cells intestinal tissue monkey 10 x 05 (test system) 7.30 365.00FA 1380-1010-1 acini and islets pancreas monkey 10 x 10 (test system) 6.60 660.00FA 1380-2005-1 20 x 05 (test system) 6.90 690.00FB 1380-1003-1 10 x 03 (single slides) 5.70 171.00FB 1380-1005-1 10 x 05 (single slides) 5.50 275.00FB 1380-1010-1 10 x 10 (single slides) 4.90 490.00FB 1380-2005-1 20 x 05 (single slides) 5.20 520.00

FA 1380-1005-2 “Mosaic Intestine/Pancreas/pANCA/ANA” 4 BIOCHIPs per field: 10 x 05 (test system) 9.00 450.00FA 1380-2005-2 cANCA, pANCA granulocytes (EOH) human 20 x 05 (test system) 8.50 850.00FB 1380-1005-2 intestinal goblet cells intestinal tissue monkey 10 x 05 (single slides) 6.70 335.00FB 1380-2005-2 acini and islets pancreas monkey 20 x 05 (single slides) 6.40 640.00

cell nuclei (ANA) liver monkey

FA 1380-1003-3 acini and islets pancreas monkey 10 x 03 (test system) 10.60 318.00FA 1380-1005-3 intestinal goblet cells intestinal tissue monkey 10 x 05 (test system) 10.20 510.00FA 1380-1010-3 saccharomyces cerevisiae fungal smear S. cerevisiae 10 x 10 (test system) 9.20 920.00FA 1380-2005-3 cANCA, pANCA, GS-ANA granulocytes (EOH) human 20 x 05 (test system) 9.70 970.00FB 1380-1003-3 (4 BIOCHIPs per field) 10 x 03 (single slides) 8.00 240.00FB 1380-1005-3 10 x 05 (single slides) 7.70 385.00FB 1380-1010-3 10 x 10 (single slides) 6.90 690.00FB 1380-2005-3 20 x 05 (single slides) 7.30 730.00

FA 1380-1003-4 “CIBD Profile 1” 10 x 03 (test system) 10.60 318.00FA 1380-1005-4 upper row : 10 x 05 (test system) 10.20 510.00FB 1380-1003-4 acini and islets pancreas monkey 10 x 03 (single slides) 8.00 240.00FB 1380-1005-4 intestinal goblet cells intestinal tissue monkey 10 x 05 (single slides) 7.70 385.00

cANCA, pANCA, GS-ANA granulocytes (EOH) humanbottom row :

saccharomyces cerevisiae fungal smear S. cerevisiaeformat 1003: slides with 3 patient profilesformat 1005: slides with 5 patient profiles

Saccharomyces cerevisiae as single substrate see page 154 (FV 2841).

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*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

FA 1381-1003 intestinal goblet cells goblet cells EU 80 10 x 03 (test system) 4.80 144.00FA 1381-1005 10 x 05 (test system) 4.60 230.00FA 1381-1010 10 x 10 (test system) 4.10 410.00FA 1381-2005 20 x 05 (test system) 4.40 440.00FB 1381-1003 10 x 03 (single slides) 3.60 108.00FB 1381-1005 10 x 05 (single slides) 3.50 175.00FB 1381-1010 10 x 10 (single slides) 3.10 310.00FB 1381-2005 20 x 05 (single slides) 3.30 330.00

FA 1381-1003-1 “Mosaic goblet cells/pancreas” 2 BIOCHIPs per field: 10 x 03 (test system) 7.60 228.00FA 1381-1005-1 intestinal goblet cells goblet cells EU 80 10 x 05 (test system) 7.30 365.00FA 1381-2005-1 acini and islets pancreas monkey 20 x 05 (test system) 6.90 690.00FB 1381-1003-1 10 x 03 (single slides) 5.70 171.00FB 1381-1005-1 10 x 05 (single slides) 5.50 275.00FB 1381-2005-1 20 x 05 (single slides) 5.20 520.00

FA 1381-1003-2 cANCA, pANCA granulocytes (EOH) human 10 x 03 (test system) 9.30 279.00FA 1381-1005-2 intestinal goblet cells goblet cells EU 80 10 x 05 (test system) 9.00 450.00FA 1381-2005-2 acini and islets pancreas monkey 20 x 05 (test system) 8.50 850.00FB 1381-1003-2 cell nuclei (ANA) liver monkey 10 x 03 (single slides) 7.00 210.00FB 1381-1005-2 (4 BIOCHIPs per field) 10 x 05 (single slides) 6.70 335.00FB 1381-2005-2 20 x 05 (single slides) 6.40 640.00

FA 1381-1003-3 acini and islets pancreas monkey 10 x 03 (test system) 10.60 318.00FA 1381-1005-3 intestinal goblet cells goblet cells EU 80 10 x 05 (test system) 10.20 510.00FA 1381-2005-3 saccharomyces cerevisiae fungal smear S. cerevisiae 20 x 05 (test system) 9.70 970.00FB 1381-1003-3 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 03 (single slides) 8.00 240.00FB 1381-1005-3 (4 BIOCHIPs per field) 10 x 05 (single slides) 7.70 385.00FB 1381-2005-3 20 x 05 (single slides) 7.30 730.00

FA 1381-1003-4 “CIBD Profile 2” 10 x 03 (test system) 10.60 318.00FA 1381-1005-4 upper row : 10 x 05 (test system) 10.20 510.00FA 1381-2005-4 acini and islets pancreas monkey 20 x 05 (test system) 9.70 970.00FB 1381-1003-4 intestinal goblet cells goblet cells EU 80 10 x 03 (single slides) 8.00 240.00FB 1381-1005-4 cANCA, pANCA, GS-ANA granulocytes (EOH) human 10 x 05 (single slides) 7.70 385.00FB 1381-2005-4 bottom row : 20 x 05 (single slides) 7.30 730.00

saccharomyces cerevisiae fungal smear S. cerevisiaeformat 1003: slides with 3 patient profilesformat 1005: slides with 5 patient profiles

FA 1420-1003 parotid gland parotid gland monkey 10 x 03 (test system) 4.80 144.00FA 1420-1005 excretory ducts 10 x 05 (test system) 4.60 230.00FA 1420-1010 and acini 10 x 10 (test system) 4.10 410.00FA 1420-2005 20 x 05 (test system) 4.40 440.00FB 1420-1003 10 x 03 (single slides) 3.60 108.00FB 1420-1005 10 x 05 (single slides) 3.50 175.00FB 1420-1010 10 x 10 (single slides) 3.10 310.00FB 1420-2005 20 x 05 (single slides) 3.30 330.00

FA 1430-1003 skeletal muscle musculus iliopsoas monkey 10 x 03 (test system) 4.80 144.00FA 1430-1005 10 x 05 (test system) 4.60 230.00FA 1430-1010 10 x 10 (test system) 4.10 410.00FA 1430-2005 20 x 05 (test system) 4.40 440.00FB 1430-1003 10 x 03 (single slides) 3.60 108.00FB 1430-1005 10 x 05 (single slides) 3.50 175.00FB 1430-1010 10 x 10 (single slides) 3.10 310.00FB 1430-2005 20 x 05 (single slides) 3.30 330.00

FA 1430-1003-1 “Mosaic Skeletal Muscle/Heart Muscle” 2 BIOCHIPs per field: 10 x 03 (test system) 7.60 228.00FA 1430-1005-1 skeletal muscle musculus iliopsoas monkey 10 x 05 (test system) 7.30 365.00FA 1430-1010-1 heart muscle heart monkey 10 x 10 (test system) 6.60 660.00FA 1430-2005-1 20 x 05 (test system) 6.90 690.00FB 1430-1003-1 10 x 03 (single slides) 5.70 171.00FB 1430-1005-1 10 x 05 (single slides) 5.50 275.00FB 1430-1010-1 10 x 10 (single slides) 4.90 490.00FB 1430-2005-1 20 x 05 (single slides) 5.20 520.00

FA 1460-1003 * heart muscle heart rat 10 x 03 (test system) 4.80 144.00FA 1460-1005 * 10 x 05 (test system) 4.60 230.00FA 1460-1010 * 10 x 10 (test system) 4.10 410.00FA 1460-2005 * 20 x 05 (test system) 4.40 440.00FB 1460-1003 * 10 x 03 (single slides) 2.40 72.00FB 1460-1005 * 10 x 05 (single slides) 2.30 115.00FB 1460-1010 * 10 x 10 (single slides) 2.10 210.00FB 1460-2005 * 20 x 05 (single slides) 2.20 220.00

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*) Currently not available as IVD in the European Union.

FA 1461-1003 heart muscle heart monkey 10 x 03 (test system) 4.80 144.00FA 1461-1005 10 x 05 (test system) 4.60 230.00FA 1461-1010 10 x 10 (test system) 4.10 410.00FA 1461-2005 20 x 05 (test system) 4.40 440.00FB 1461-1003 10 x 03 (single slides) 3.60 108.00FB 1461-1005 10 x 05 (single slides) 3.50 175.00FB 1461-1010 10 x 10 (single slides) 3.10 310.00FB 1461-2005 20 x 05 (single slides) 3.30 330.00

FA 1461-1005-4 heart muscle heart monkey 10 x 05 (test system) 5.30 265.00FA 1461-1010-4 mitochondria (AMA) kidney rat 10 x 10 (test system) 4.70 470.00FA 1461-2005-4 (2 BIOCHIPs per field) 20 x 05 (test system) 5.00 500.00FB 1461-1005-4 10 x 05 (single slides) 4.00 200.00FB 1461-1010-4 10 x 10 (single slides) 3.60 360.00FB 1461-2005-4 20 x 05 (single slides) 3.80 380.00

FA 1480-1003 * cartilage trachea monkey 10 x 03 (test system) 4.80 144.00FA 1480-1005 * 10 x 05 (test system) 4.60 230.00FA 1480-1010 * 10 x 10 (test system) 4.10 410.00FA 1480-2005 * 20 x 05 (test system) 4.40 440.00FB 1480-1003 * 10 x 03 (single slides) 3.60 108.00FB 1480-1005 * 10 x 05 (single slides) 3.50 175.00FB 1480-1010 * 10 x 10 (single slides) 3.10 310.00FB 1480-2005 * 20 x 05 (single slides) 3.30 330.00

FA 1501-1003 epidermis: oesophagus monkey 10 x 03 (test system) 4.80 144.00FA 1501-1005 prickle cell desmosomes 10 x 05 (test system) 4.60 230.00FA 1501-1010 epidermal basement membrane 10 x 10 (test system) 4.10 410.00FA 1501-2005 20 x 05 (test system) 4.40 440.00FB 1501-1003 10 x 03 (single slides) 3.60 108.00FB 1501-1005 10 x 05 (single slides) 3.50 175.00FB 1501-1010 10 x 10 (single slides) 3.10 310.00FB 1501-2005 20 x 05 (single slides) 3.30 330.00

FA 1501-1003-1 epidermis oesophagus monkey 10 x 03 (test system) 7.60 228.00FA 1501-1005-1 epidermis tongue monkey 10 x 05 (test system) 7.30 365.00FA 1501-1010-1 (2 BIOCHIPs per field) 10 x 10 (test system) 6.60 660.00FA 1501-2005-1 20 x 05 (test system) 6.90 690.00FB 1501-1003-1 10 x 03 (single slides) 5.70 171.00FB 1501-1005-1 10 x 05 (single slides) 5.50 275.00FB 1501-1010-1 10 x 10 (single slides) 4.90 490.00FB 1501-2005-1 20 x 05 (single slides) 5.20 520.00

FA 1502-1003 epidermis: tongue monkey 10 x 03 (test system) 4.80 144.00FA 1502-1005 prickle cell desmosomes 10 x 05 (test system) 4.60 230.00FA 1502-1010 epidermal basement membrane 10 x 10 (test system) 4.10 410.00FA 1502-2005 20 x 05 (test system) 4.40 440.00FB 1502-1003 10 x 03 (single slides) 3.60 108.00FB 1502-1005 10 x 05 (single slides) 3.50 175.00FB 1502-1010 10 x 10 (single slides) 3.10 310.00FB 1502-2005 20 x 05 (single slides) 3.30 330.00

FA 1503-1003 keratin oesophagus rat 10 x 03 (test system) 3.20 96.00FA 1503-1005 (filaggrin, “RA keratin”) 10 x 05 (test system) 3.10 155.00FA 1503-1010 10 x 10 (test system) 2.70 270.00FA 1503-2005 20 x 05 (test system) 2.90 290.00FB 1503-1003 10 x 03 (single slides) 2.40 72.00FB 1503-1005 10 x 05 (single slides) 2.30 115.00FB 1503-1010 10 x 10 (single slides) 2.10 210.00FB 1503-2005 20 x 05 (single slides) 2.20 220.00

FA 1507-1005 transitional epithelium bladder mucosa rat 10 x 05 (test system) 3.10 155.00FA 1507-1010 (detection of paraneoplastic pemphigus) 10 x 10 (test system) 2.70 270.00FA 1507-2005 20 x 05 (test system) 2.90 290.00FB 1507-1005 10 x 05 (single slides) 2.30 115.00FB 1507-1010 10 x 10 (single slides) 2.10 210.00FB 1507-2005 20 x 05 (single slides) 2.20 220.00

Price (€)

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Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Organ-Specific Autoantibodies

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Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies

FA 1510-0010-1 cell nuclei HEp-2 cells human 100 x 10 (test system) 1.70 1,700.00FA 1510-1003-1 (ANA global test) liver monkey 10 x 03 (test system) 2.20 66.00FA 1510-1005-1 (2 BIOCHIPs per field) 10 x 05 (test system) 2.10 105.00FA 1510-1010-1 10 x 10 (test system) 1.90 190.00FA 1510-1050-1 10 x 50 (test system) 1.10 550.00FA 1510-2003-1 20 x 03 (test system) 2.10 126.00FA 1510-2005-1 20 x 05 (test system) 2.00 200.00FA 1510-2010-1 20 x 10 (test system) 1.80 360.00FA 1510-5010-1 50 x 10 (test system) 1.70 850.00FB 1510-0010-1 100 x 10 (single slides) 1.30 1,300.00FB 1510-1003-1 10 x 03 (single slides) 1.70 51.00FB 1510-1005-1 10 x 05 (single slides) 1.60 80.00FB 1510-1010-1 10 x 10 (single slides) 1.40 140.00FB 1510-1050-1 10 x 50 (single slides) 0.80 400.00FB 1510-2003-1 20 x 03 (single slides) 1.60 96.00FB 1510-2005-1 20 x 05 (single slides) 1.50 150.00FB 1510-2010-1 20 x 10 (single slides) 1.40 280.00FB 1510-5010-1 50 x 10 (single slides) 1.30 650.00

FA 1510-1003-2 cell nuclei (ANA) HEp-2 cells human 10 x 03 (test system) 3.30 99.00FA 1510-1005-2 mitochondria (AMA) kidney rat 10 x 05 (test system) 3.20 160.00FA 1510-1010-2 (2 BIOCHIPs per field) 10 x 10 (test system) 2.90 290.00FA 1510-2005-2 20 x 05 (test system) 3.10 310.00FB 1510-1003-2 10 x 03 (single slides) 2.50 75.00FB 1510-1005-2 10 x 05 (single slides) 2.40 120.00FB 1510-1010-2 10 x 10 (single slides) 2.20 220.00FB 1510-2005-2 20 x 05 (single slides) 2.30 230.00

FA 1510-1005-20 “EUROPLUS ANA Mosaic 20” 4 BIOCHIPs per field: 10 x 05 (test system) 13.30 665.00FA 1510-1010-20 cell nuclei (ANA) HEp-2 cells human 10 x 10 (test system) 12.00 1,200.00FA 1510-2005-20 cell nuclei (ANA) liver monkey 20 x 05 (test system) 12.60 1,260.00FB 1510-1005-20 SS-A + SS-B SS-A+SS-B BIOCHIPs 10 x 05 (single slides) 10.00 500.00FB 1510-1010-20 ribosomal P-proteins + Jo-1 rib. P-prot.+Jo-1 BIOCHIPs 10 x 10 (single slides) 9.00 900.00FB 1510-2005-20 20 x 05 (single slides) 9.50 950.00

FA 1510-1005-21 “EUROPLUS ANA Mosaic 21” 4 BIOCHIPs per field: 10 x 05 (test system) 16.10 805.00FA 1510-1010-21 cell nuclei (ANA) HEp-2 cells human 10 x 10 (test system) 14.60 1,460.00FA 1510-2005-21 cell nuclei (ANA) liver monkey 20 x 05 (test system) 15.30 1,530.00FB 1510-1005-21 nRNP/Sm + Sm + SS-A nRNP/Sm+Sm+SS-A BIOCHIPs 10 x 05 (single slides) 12.10 605.00FB 1510-1010-21 SS-B + ribosomal P-proteins + Jo-1 SS-B+rib. P-prot.+Jo-1 BIOCHIPs 10 x 10 (single slides) 10.90 1,090.00FB 1510-2005-21 20 x 05 (single slides) 11.50 1,150.00

FA 1510-1005-22 “EUROPLUS ANA Mosaic 22” 4 BIOCHIPs per field: 10 x 05 (test system) 16.10 805.00FA 1510-1010-22 cell nuclei (ANA) HEp-2 cells human 10 x 10 (test system) 14.60 1,460.00FA 1510-2005-22 cell nuclei (ANA) liver monkey 20 x 05 (test system) 15.30 1,530.00FB 1510-1005-22 nRNP/Sm + Sm + SS-A nRNP/Sm+Sm+SS-A BIOCHIPs 10 x 05 (single slides) 12.10 605.00FB 1510-1010-22 SS-B + Scl-70 + Jo-1 SS-B+Scl-70+Jo-1 BIOCHIPs 10 x 10 (single slides) 10.90 1,090.00FB 1510-2005-22 20 x 05 (single slides) 11.50 1,150.00

FA 1512-0010-1 cell nuclei HEp-20-10 cells human 100 x 10 (test system) 1.70 1,700.00FA 1512-1003-1 (ANA global test) liver monkey 10 x 03 (test system) 2.20 66.00FA 1512-1005-1 (2 BIOCHIPs per field) 10 x 05 (test system) 2.10 105.00FA 1512-1010-1 10 x 10 (test system) 1.90 190.00FA 1512-1050-1 10 x 50 (test system) 1.10 550.00FA 1512-2003-1 20 x 03 (test system) 2.10 126.00FA 1512-2005-1 20 x 05 (test system) 2.00 200.00FA 1512-2010-1 20 x 10 (test system) 1.80 360.00FA 1512-5010-1 50 x 10 (test system) 1.70 850.00FB 1512-0010-1 100 x 10 (single slides) 1.30 1,300.00FB 1512-1003-1 10 x 03 (single slides) 1.70 51.00FB 1512-1005-1 10 x 05 (single slides) 1.60 80.00FB 1512-1010-1 10 x 10 (single slides) 1.40 140.00FB 1512-1050-1 10 x 50 (single slides) 0.80 400.00FB 1512-2003-1 20 x 03 (single slides) 1.60 96.00FB 1512-2005-1 20 x 05 (single slides) 1.50 150.00FB 1512-2010-1 20 x 10 (single slides) 1.40 280.00FB 1512-5010-1 50 x 10 (single slides) 1.30 650.00

FA 1512-1003-2 cell nuclei (ANA) HEp-20-10 cells human 10 x 03 (test system) 3.30 99.00FA 1512-1005-2 mitochondria (AMA) kidney rat 10 x 05 (test system) 3.20 160.00FA 1512-1010-2 (2 BIOCHIPs per field) 10 x 10 (test system) 2.90 290.00FA 1512-2005-2 20 x 05 (test system) 3.10 310.00FB 1512-1003-2 10 x 03 (single slides) 2.50 75.00FB 1512-1005-2 10 x 05 (single slides) 2.40 120.00FB 1512-1010-2 10 x 10 (single slides) 2.20 220.00FB 1512-2005-2 20 x 05 (single slides) 2.30 230.00

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Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies

FA 1512-1005-3 cell nuclei (ANA) HEp-20-10 cells human 10 x 05 (test system) 3.20 160.00FA 1512-1010-3 cell nuclei (ANA) liver rat 10 x 10 (test system) 2.90 290.00FA 1512-2005-3 (2 BIOCHIPs per field) 20 x 05 (test system) 3.10 310.00FB 1512-1005-3 10 x 05 (single slides) 2.40 120.00FB 1512-1010-3 10 x 10 (single slides) 2.20 220.00FB 1512-2005-3 20 x 05 (single slides) 2.30 230.00

FA 1512-1005-20 “EUROPLUS ANA Mosaic 20A” 4 BIOCHIPs per field: 10 x 05 (test system) 13.30 665.00FA 1512-1010-20 cell nuclei (ANA) HEp-20-10 cells human 10 x 10 (test system) 12.00 1,200.00FA 1512-2005-20 cell nuclei (ANA) liver monkey 20 x 05 (test system) 12.60 1,260.00FB 1512-1005-20 SS-A + SS-B SS-A+SS-B BIOCHIPs 10 x 05 (single slides) 10.00 500.00FB 1512-1010-20 ribosomal P-proteins + Jo-1 rib. P-prot.+Jo-1 BIOCHIPs 10 x 10 (single slides) 9.00 900.00FB 1512-2005-20 20 x 05 (single slides) 9.50 950.00

FA 1512-1005-21 “EUROPLUS ANA Mosaic 21A” 4 BIOCHIPs per field: 10 x 05 (test system) 16.10 805.00FA 1512-1010-21 cell nuclei (ANA) HEp-20-10 cells human 10 x 10 (test system) 14.60 1,460.00FA 1512-2005-21 cell nuclei (ANA) liver monkey 20 x 05 (test system) 15.30 1,530.00FB 1512-1005-21 nRNP/Sm + Sm + SS-A nRNP/Sm+Sm+SS-A BIOCHIPs 10 x 05 (single slides) 12.10 605.00FB 1512-1010-21 SS-B + ribosomal P-proteins + Jo-1 SS-B+rib. P-prot.+Jo-1 BIOCHIPs 10 x 10 (single slides) 10.90 1,090.00FB 1512-2005-21 20 x 05 (single slides) 11.50 1,150.00

FA 1512-1005-22 “EUROPLUS ANA Mosaic 22A” 4 BIOCHIPs per field: 10 x 05 (test system) 16.10 805.00FA 1512-1010-22 cell nuclei (ANA) HEp-20-10 cells human 10 x 10 (test system) 14.60 1,460.00FA 1512-2005-22 cell nuclei (ANA) liver monkey 20 x 05 (test system) 15.30 1,530.00FB 1512-1005-22 nRNP/Sm + Sm + SS-A nRNP/Sm+Sm+SS-A BIOCHIPs 10 x 05 (single slides) 12.10 605.00FB 1512-1010-22 SS-B + Scl-70 + Jo-1 SS-B+Scl-70+Jo-1 BIOCHIPs 10 x 10 (single slides) 10.90 1,090.00FB 1512-2005-22 20 x 05 (single slides) 11.50 1,150.00

FA 1520-0010 cell nuclei (ANA) HEp-2 cells human 100 x 10 (test system) 1.60 1,600.00FA 1520-1003 10 x 03 (test system) 2.10 63.00FA 1520-1005 10 x 05 (test system) 2.00 100.00FA 1520-1010 10 x 10 (test system) 1.80 180.00FA 1520-1050 10 x 50 (test system) 1.05 525.00FA 1520-1096 10 x 96 (test system) 1.00 960.00FA 1520-2003 20 x 03 (test system) 2.00 120.00FA 1520-2005 20 x 05 (test system) 1.90 190.00FA 1520-2010 20 x 10 (test system) 1.70 340.00FA 1520-5010 50 x 10 (test system) 1.70 850.00FB 1520-0010 100 x 10 (single slides) 1.25 1,250.00FB 1520-1003 10 x 03 (single slides) 1.60 48.00FB 1520-1005 10 x 05 (single slides) 1.50 75.00FB 1520-1010 10 x 10 (single slides) 1.40 140.00FB 1520-1050 10 x 50 (single slides) 0.80 400.00FB 1520-1096 10 x 96 (single slides) 0.80 768.00FB 1520-2005 20 x 05 (single slides) 1.50 150.00FB 1520-2010 20 x 10 (single slides) 1.30 260.00FB 1520-5010 50 x 10 (single slides) 1.30 650.00

FA 1522-0010 cell nuclei (ANA) HEp-20-10 cells human 100 x 10 (test system) 1.60 1,600.00FA 1522-1003 10 x 03 (test system) 2.10 63.00FA 1522-1005 10 x 05 (test system) 2.00 100.00FA 1522-1010 10 x 10 (test system) 1.80 180.00FA 1522-1050 10 x 50 (test system) 1.05 525.00FA 1522-1096 10 x 96 (test system) 1.00 960.00FA 1522-2003 20 x 03 (test system) 2.00 120.00FA 1522-2005 20 x 05 (test system) 1.90 190.00FA 1522-2010 20 x 10 (test system) 1.70 340.00FA 1522-5010 50 x 10 (test system) 1.70 850.00FB 1522-0010 100 x 10 (single slides) 1.25 1,250.00FB 1522-1003 10 x 03 (single slides) 1.60 48.00FB 1522-1005 10 x 05 (single slides) 1.50 75.00FB 1522-1010 10 x 10 (single slides) 1.40 140.00FB 1522-1050 10 x 50 (single slides) 0.80 400.00FB 1522-1096 10 x 96 (single slides) 0.80 768.00FB 1522-2005 20 x 05 (single slides) 1.50 150.00FB 1522-2010 20 x 10 (single slides) 1.30 260.00FB 1522-5010 50 x 10 (single slides) 1.30 650.00

FA 1560-1005 cell nuclei (ANA) liver rat 10 x 05 (test system) 2.00 100.00FA 1560-1010 10 x 10 (test system) 1.80 180.00FA 1560-2005 20 x 05 (test system) 1.90 190.00FB 1560-1005 10 x 05 (single slides) 1.50 75.00FB 1560-1010 10 x 10 (single slides) 1.40 140.00FB 1560-2005 20 x 05 (single slides) 1.50 150.00

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Slides x Fields

Order No. Price (€)

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Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies

FA 1570-1005 cell nuclei (ANA) liver monkey 10 x 05 (test system) 3.10 155.00FA 1570-1010 10 x 10 (test system) 2.70 270.00FA 1570-2005 20 x 05 (test system) 2.90 290.00FB 1570-1005 10 x 05 (single slides) 2.30 115.00FB 1570-1010 10 x 10 (single slides) 2.10 210.00FB 1570-2005 20 x 05 (single slides) 2.20 220.00

FA 1572-1003 dsDNA flagellates Crithidia luciliae 10 x 03 (test system) 2.60 78.00FA 1572-1005 10 x 05 (test system) 2.50 125.00FA 1572-1010 10 x 10 (test system) 2.30 230.00FA 1572-2003 20 x 03 (test system) 2.50 150.00FA 1572-2005 20 x 05 (test system) 2.40 240.00FA 1572-2010 20 x 10 (test system) 2.20 440.00FB 1572-1003 10 x 03 (single slides) 2.00 60.00FB 1572-1005 10 x 05 (single slides) 1.90 95.00FB 1572-1010 10 x 10 (single slides) 1.70 170.00FB 1572-2003 20 x 03 (single slides) 1.90 114.00FB 1572-2005 20 x 05 (single slides) 1.80 180.00FB 1572-2010 20 x 10 (single slides) 1.70 340.00

FA 1599-1001-2 “Autoantibody Profile 2” Combination of 30 different tissues per slide for Price and size of kitFB 1599-1001-2 the detection of autoantibodies (BIOCHIP Mosaic). according to prior agreement.

FA 1620-1003 mitochondria (AMA) kidney rat 10 x 03 (test system) 2.10 63.00FA 1620-1005 10 x 05 (test system) 2.00 100.00FA 1620-1010 10 x 10 (test system) 1.80 180.00FA 1620-2005 20 x 05 (test system) 1.90 190.00FB 1620-1003 10 x 03 (single slides) 1.60 48.00FB 1620-1005 10 x 05 (single slides) 1.50 75.00FB 1620-1010 10 x 10 (single slides) 1.40 140.00FB 1620-2005 20 x 05 (single slides) 1.50 150.00

FA 1620-1003-1 mitochondria (AMA) kidney rat 10 x 03 (test system) 3.30 99.00FA 1620-1005-1 smooth muscles (ASMA) stomach rat 10 x 05 (test system) 3.20 160.00FA 1620-1010-1 (2 BIOCHIPs per field) 10 x 10 (test system) 2.90 290.00FA 1620-2005-1 20 x 05 (test system) 3.10 310.00FB 1620-1003-1 10 x 03 (single slides) 2.50 75.00FB 1620-1005-1 10 x 05 (single slides) 2.40 120.00FB 1620-1010-1 10 x 10 (single slides) 2.20 220.00FB 1620-2005-1 20 x 05 (single slides) 2.30 230.00

FA 1620-1003-2 mitochondria (AMA) kidney mouse 10 x 03 (test system) 3.30 99.00FA 1620-1005-2 smooth muscles (ASMA) stomach mouse 10 x 05 (test system) 3.20 160.00FA 1620-1010-2 (2 BIOCHIPs per field) 10 x 10 (test system) 2.90 290.00FA 1620-2005-2 20 x 05 (test system) 3.10 310.00FB 1620-1003-2 10 x 03 (single slides) 2.50 75.00FB 1620-1005-2 10 x 05 (single slides) 2.40 120.00FB 1620-1010-2 10 x 10 (single slides) 2.20 220.00FB 1620-2005-2 20 x 05 (single slides) 2.30 230.00

FA 1620-1003-3 “EUROPLUS” 2 BIOCHIPs per field: 10 x 03 (test system) 4.20 126.00FA 1620-1005-3 mitochondria (AMA) kidney rat 10 x 05 (test system) 4.00 200.00FA 1620-1010-3 M2 antigen M2 BIOCHIPs 10 x 10 (test system) 3.60 360.00FA 1620-2005-3 20 x 05 (test system) 3.80 380.00FB 1620-1003-3 10 x 03 (single slides) 3.20 96.00FB 1620-1005-3 10 x 05 (single slides) 3.10 155.00FB 1620-1010-3 10 x 10 (single slides) 2.70 270.00FB 1620-2005-3 20 x 05 (single slides) 2.90 290.00

FA 1620-1003-5 “EUROPLUS” 4 BIOCHIPs per field: 10 x 03 (test system) 6.30 189.00FA 1620-1005-5 mitochondria (AMA) kidney rat 10 x 05 (test system) 6.10 305.00FA 1620-1010-5 smooth muscles (ASMA) stomach rat 10 x 10 (test system) 5.50 550.00FA 1620-2005-5 cell nuclei (ANA) HEp-2 cells human 20 x 05 (test system) 5.80 580.00FB 1620-1003-5 M2 antigen M2 BIOCHIPs 10 x 03 (single slides) 4.70 141.00FB 1620-1005-5 10 x 05 (single slides) 4.60 230.00FB 1620-1010-5 10 x 10 (single slides) 4.10 410.00FB 1620-2005-5 20 x 05 (single slides) 4.30 430.00

FA 1621-1003 mitochondria kidney mouse 10 x 03 (test system) 2.10 63.00FA 1621-1005 (AMA) 10 x 05 (test system) 2.00 100.00FA 1621-1010 10 x 10 (test system) 1.80 180.00FA 1621-2005 20 x 05 (test system) 1.90 190.00FB 1621-1003 10 x 03 (single slides) 1.60 48.00FB 1621-1005 10 x 05 (single slides) 1.50 75.00FB 1621-1010 10 x 10 (single slides) 1.40 140.00FB 1621-2005 20 x 05 (single slides) 1.50 150.00

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FA 1622-1005 M2 antigen M2 BIOCHIPs 10 x 05 (test system) 3.10 155.00FA 1622-1010 10 x 10 (test system) 2.70 270.00FA 1622-2005 20 x 05 (test system) 2.90 290.00FB 1622-1005 10 x 05 (single slides) 2.30 115.00FB 1622-1010 10 x 10 (single slides) 2.10 210.00FB 1622-2005 20 x 05 (single slides) 2.20 220.00

FA 1651-1003 F-actin VSM47 rat 10 x 03 (test system) 2.10 63.00FA 1651-1005 10 x 05 (test system) 2.00 100.00FA 1651-1010 10 x 10 (test system) 1.80 180.00FA 1651-2005 20 x 05 (test system) 1.90 190.00FB 1651-1003 10 x 03 (single slides) 1.60 48.00FB 1651-1005 10 x 05 (single slides) 1.50 75.00FB 1651-1010 10 x 10 (single slides) 1.40 140.00FB 1651-2005 20 x 05 (single slides) 1.50 150.00

FA 1710-1003 smooth muscles stomach rat 10 x 03 (test system) 2.10 63.00FA 1710-1005 (ASMA) 10 x 05 (test system) 2.00 100.00FA 1710-1010 10 x 10 (test system) 1.80 180.00FA 1710-2005 20 x 05 (test system) 1.90 190.00FB 1710-1003 10 x 03 (single slides) 1.60 48.00FB 1710-1005 10 x 05 (single slides) 1.50 75.00FB 1710-1010 10 x 10 (single slides) 1.40 140.00FB 1710-2005 20 x 05 (single slides) 1.50 150.00

FA 1711-1003 smooth muscles stomach mouse 10 x 03 (test system) 2.10 63.00FA 1711-1005 (ASMA) 10 x 05 (test system) 2.00 100.00FA 1711-1010 10 x 10 (test system) 1.80 180.00FA 1711-2005 20 x 05 (test system) 1.90 190.00FB 1711-1003 10 x 03 (single slides) 1.60 48.00FB 1711-1005 10 x 05 (single slides) 1.50 75.00FB 1711-1010 10 x 10 (single slides) 1.40 140.00FB 1711-2005 20 x 05 (single slides) 1.50 150.00

FA 1800-1003-1 “Mosaic Basic Profile 1” 3 BIOCHIPs per field: 10 x 03 (test system) 4.30 129.00FA 1800-1005-1 cell nuclei (ANA) HEp-2 cells human 10 x 05 (test system) 4.20 210.00FA 1800-1010-1 mitochondria (AMA) kidney rat 10 x 10 (test system) 3.80 380.00FA 1800-2005-1 smooth muscles (ASMA) stomach rat 20 x 05 (test system) 4.00 400.00FB 1800-1003-1 10 x 03 (single slides) 3.30 99.00FB 1800-1005-1 10 x 05 (single slides) 3.20 160.00FB 1800-1010-1 10 x 10 (single slides) 2.90 290.00FB 1800-2005-1 20 x 05 (single slides) 3.00 300.00

FA 1800-1003-2 “Mosaic Basic Profile 2” 3 BIOCHIPs per field: 10 x 03 (test system) 4.30 129.00FA 1800-1005-2 cell nuclei (ANA) liver rat 10 x 05 (test system) 4.20 210.00FA 1800-1010-2 mitochondria (AMA) kidney rat 10 x 10 (test system) 3.80 380.00FA 1800-2005-2 smooth muscles (ASMA) stomach rat 20 x 05 (test system) 4.00 400.00FB 1800-1003-2 10 x 03 (single slides) 3.30 99.00FB 1800-1005-2 10 x 05 (single slides) 3.20 160.00FB 1800-1010-2 10 x 10 (single slides) 2.90 290.00FB 1800-2005-2 20 x 05 (single slides) 3.00 300.00

FA 1800-1003-3 “Mosaic Basic Profile 3” 4 BIOCHIPs per field: 10 x 03 (test system) 4.60 138.00FA 1800-1005-3 cell nuclei (ANA) HEp-2 cells human 10 x 05 (test system) 4.50 225.00FA 1800-1010-3 cell nuclei (ANA), liver antigens liver monkey 10 x 10 (test system) 4.00 400.00FA 1800-2005-3 mitochondria (AMA) kidney rat 20 x 05 (test system) 4.30 430.00FB 1800-1003-3 smooth muscles (ASMA) stomach rat 10 x 03 (single slides) 3.50 105.00FB 1800-1005-3 10 x 05 (single slides) 3.40 170.00FB 1800-1010-3 10 x 10 (single slides) 3.10 310.00FB 1800-2005-3 20 x 05 (single slides) 3.20 320.00

FA 1800-1005-4 “Mosaic Basic Profile 4” 5 BIOCHIPs per field: 10 x 05 (test system) 6.00 300.00FA 1800-2005-4 cell nuclei (ANA) HEp-2 cells human 20 x 05 (test system) 5.70 570.00FB 1800-1005-4 cell nuclei (ANA), liver antigens liver monkey 10 x 05 (single slides) 4.50 225.00FB 1800-2005-4 dsDNA flagellates Crithidia luciliae 20 x 05 (single slides) 4.30 430.00

mitochondria (AMA) kidney ratsmooth muscles (ASMA) stomach rat

FA 1800-1005-6 “Mosaic Basic Profile 6” 6 BIOCHIPs per field: 10 x 05 (test system) 10.20 510.00FA 1800-2005-6 skeletal muscle musculus iliopsoas monkey 20 x 05 (test system) 9.70 970.00FB 1800-1005-6 heart muscle heart monkey 10 x 05 (single slides) 7.70 385.00FB 1800-2005-6 cell nuclei (ANA) HEp-2 cells human 20 x 05 (single slides) 7.20 720.00

cell nuclei (ANA), liver antigens liver monkeymitochondria (AMA) kidney rat

smooth muscles (ASMA) stomach rat

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies

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FA 1800-1003-7 “Mosaic Basic Profile 7” 3 BIOCHIPs per field: 10 x 03 (test system) 3.40 102.00FA 1800-1005-7 cell nuclei (ANA) HEp-2 cells human 10 x 05 (test system) 3.30 165.00FA 1800-1010-7 cell nuclei (ANA) liver monkey 10 x 10 (test system) 3.00 300.00FA 1800-2005-7 mitochondria (AMA) kidney rat 20 x 05 (test system) 3.10 310.00FB 1800-1003-7 10 x 03 (single slides) 2.60 78.00FB 1800-1005-7 10 x 05 (single slides) 2.40 120.00FB 1800-1010-7 10 x 10 (single slides) 2.20 220.00FB 1800-2005-7 20 x 05 (single slides) 2.30 230.00

FA 1800-1003-25 “Mosaic Basis Profile 25” 4 BIOCHIPs per field: 10 x 03 (test system) 4.60 138.00FA 1800-1005-25 cell nuclei (ANA) liver rat 10 x 05 (test system) 4.50 225.00FA 1800-1010-25 cell nuclei (ANA) liver monkey 10 x 10 (test system) 4.00 400.00FA 1800-2005-25 mitochondria (AMA) kidney rat 20 x 05 (test system) 4.30 430.00FB 1800-1003-25 smooth muscles (ASMA) stomach rat 10 x 03 (single slides) 3.50 105.00FB 1800-1005-25 10 x 05 (single slides) 3.40 170.00FB 1800-1010-25 10 x 10 (single slides) 3.10 310.00FB 1800-2005-25 20 x 05 (single slides) 3.20 320.00

FA 1802-1003-1 “Mosaic Basic Profile 1A” 3 BIOCHIPs per field: 10 x 03 (test system) 4.30 129.00FA 1802-1005-1 cell nuclei (ANA) HEp-20-10 cells human 10 x 05 (test system) 4.20 210.00FA 1802-1010-1 mitochondria (AMA) kidney rat 10 x 10 (test system) 3.80 380.00FA 1802-2005-1 smooth muscles (ASMA) stomach rat 20 x 05 (test system) 4.00 400.00FB 1802-1003-1 10 x 03 (single slides) 3.30 99.00FB 1802-1005-1 10 x 05 (single slides) 3.20 160.00FB 1802-1010-1 10 x 10 (single slides) 2.90 290.00FB 1802-2005-1 20 x 05 (single slides) 3.00 300.00

FA 1802-1003-3 “Mosaic Basic Profile 3A” 4 BIOCHIPs per field: 10 x 03 (test system) 4.60 138.00FA 1802-1005-3 cell nuclei (ANA) HEp-20-10 cells human 10 x 05 (test system) 4.50 225.00FA 1802-1010-3 cell nuclei (ANA), liver antigens liver monkey 10 x 10 (test system) 4.00 400.00FA 1802-2005-3 mitochondria (AMA) kidney rat 20 x 05 (test system) 4.30 430.00FB 1802-1003-3 smooth muscles (ASMA) stomach rat 10 x 03 (single slides) 3.50 105.00FB 1802-1005-3 10 x 05 (single slides) 3.40 170.00FB 1802-1010-3 10 x 10 (single slides) 3.10 310.00FB 1802-2005-3 20 x 05 (single slides) 3.20 320.00

FA 1805-1003-13 “Mosaic Basic Profile 13B” 4 BIOCHIPs per field: 10 x 03 (test system) 5.60 168.00FA 1805-1005-13 cell nuclei (ANA) HEp-2 cells human 10 x 05 (test system) 5.40 270.00FA 1805-1010-13 cell nuclei (ANA) liver rat 10 x 10 (test system) 4.80 480.00FA 1805-2005-13 mitochondria (AMA) kidney rat 20 x 05 (test system) 5.10 510.00FB 1805-1003-13 smooth muscles (ASMA) stomach rat 10 x 03 (single slides) 4.20 126.00FB 1805-1005-13 10 x 05 (single slides) 4.00 200.00FB 1805-1010-13 10 x 10 (single slides) 3.70 370.00FB 1805-2005-13 20 x 05 (single slides) 3.80 380.00

FA 1812-1003-3 “Mosaic Basic Profile 3C” 4 BIOCHIPs per field: 10 x 03 (test system) 5.60 168.00FA 1812-1005-3 cell nuclei (ANA) HEp-20-10 cells human 10 x 05 (test system) 5.40 270.00FA 1812-1010-3 cell nuclei (ANA) liver rat 10 x 10 (test system) 4.80 480.00FA 1812-2005-3 mitochondria (AMA) kidney rat 20 x 05 (test system) 5.10 510.00FB 1812-1003-3 smooth muscles (ASMA) stomach rat 10 x 03 (single slides) 4.20 126.00FB 1812-1005-3 10 x 05 (single slides) 4.00 200.00FB 1812-1010-3 10 x 10 (single slides) 3.70 370.00FB 1812-2005-3 20 x 05 (single slides) 3.80 380.00

FA 1812-1005-25 “Mosaic Basic Profile 25C” 4 BIOCHIPs per field: 10 x 05 (test system) 5.40 270.00FA 1812-1010-25 cell nuclei (ANA) HEp-20-10 cells human 10 x 10 (test system) 4.80 480.00FA 1812-2005-25 cell nuclei (ANA) liver mouse 20 x 05 (test system) 5.10 510.00FB 1812-1005-25 smooth muscles (ASMA) stomach mouse 10 x 05 (single slides) 4.00 200.00FB 1812-1010-25 mitochondria (AMA) kidney mouse 10 x 10 (single slides) 3.70 370.00FB 1812-2005-25 20 x 05 (single slides) 3.80 380.00

FA 1911-1003 A endomysium, reticulin oesophagus monkey 10 x 03 (test system) 4.80 144.00FA 1911-1005 A 10 x 05 (test system) 4.60 230.00FA 1911-1010 A 10 x 10 (test system) 4.10 410.00FA 1911-2005 A 20 x 05 (test system) 4.40 440.00FB 1911-1003 A 10 x 03 (single slides) 3.60 108.00FB 1911-1005 A 10 x 05 (single slides) 3.50 175.00FB 1911-1010 A 10 x 10 (single slides) 3.10 310.00FB 1911-2005 A 20 x 05 (single slides) 3.30 330.00FA 1911-1003 G 10 x 03 (test system) 4.80 144.00FA 1911-1005 G 10 x 05 (test system) 4.60 230.00FA 1911-1010 G 10 x 10 (test system) 4.10 410.00FA 1911-2005 G 20 x 05 (test system) 4.40 440.00FB 1911-1003 G 10 x 03 (single slides) 3.60 108.00FB 1911-1005 G 10 x 05 (single slides) 3.50 175.00FB 1911-1010 G 10 x 10 (single slides) 3.10 310.00FB 1911-2005 G 20 x 05 (single slides) 3.30 330.00

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies

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Antibodies

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Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies

FA 1911-1003-1 A “EUROPLUS” 2 BIOCHIPs per field: 10 x 03 (test system) 6.30 189.00FA 1911-1005-1 A endomysium, reticulin oesophagus monkey 10 x 05 (test system) 6.10 305.00FA 1911-1010-1 A gliadin gliadin BIOCHIPs wheat 10 x 10 (test system) 5.50 550.00FA 1911-2005-1 A 20 x 05 (test system) 5.80 580.00FB 1911-1003-1 A 10 x 03 (single slides) 4.70 141.00FB 1911-1005-1 A 10 x 05 (single slides) 4.60 230.00FB 1911-1010-1 A 10 x 10 (single slides) 4.10 410.00FB 1911-2005-1 A 20 x 05 (single slides) 4.30 430.00FA 1911-1003-1 G 10 x 03 (test system) 6.30 189.00FA 1911-1005-1 G 10 x 05 (test system) 6.10 305.00FA 1911-1010-1 G 10 x 10 (test system) 5.50 550.00FA 1911-2005-1 G 20 x 05 (test system) 5.80 580.00FB 1911-1003-1 G 10 x 03 (single slides) 4.70 141.00FB 1911-1005-1 G 10 x 05 (single slides) 4.60 230.00FB 1911-1010-1 G 10 x 10 (single slides) 4.10 410.00FB 1911-2005-1 G 20 x 05 (single slides) 4.30 430.00

FA 1913-1003 A endomysium, reticulin small intestine monkey 10 x 03 (test system) 4.80 144.00FA 1913-1005 A 10 x 05 (test system) 4.60 230.00FA 1913-1010 A 10 x 10 (test system) 4.10 410.00FA 1913-2005 A 20 x 05 (test system) 4.40 440.00FB 1913-1003 A 10 x 03 (single slides) 3.60 108.00FB 1913-1005 A 10 x 05 (single slides) 3.50 175.00FB 1913-1010 A 10 x 10 (single slides) 3.10 310.00FB 1913-2005 A 20 x 05 (single slides) 3.30 330.00FA 1913-1003 G 10 x 03 (test system) 4.80 144.00FA 1913-1005 G 10 x 05 (test system) 4.60 230.00FA 1913-1010 G 10 x 10 (test system) 4.10 410.00FA 1913-2005 G 20 x 05 (test system) 4.40 440.00FB 1913-1003 G 10 x 03 (single slides) 3.60 108.00FB 1913-1005 G 10 x 05 (single slides) 3.50 175.00FB 1913-1010 G 10 x 10 (single slides) 3.10 310.00FB 1913-2005 G 20 x 05 (single slides) 3.30 330.00

FA 1913-1003-1 A “EUROPLUS” 2 BIOCHIPs per field: 10 x 03 (test system) 6.30 189.00FA 1913-1005-1 A endomysium, reticulin small intestine monkey 10 x 05 (test system) 6.10 305.00FA 1913-1010-1 A gliadin gliadin BIOCHIPs wheat 10 x 10 (test system) 5.50 550.00FA 1913-2005-1 A 20 x 05 (test system) 5.80 580.00FB 1913-1003-1 A 10 x 03 (single slides) 4.70 141.00FB 1913-1005-1 A 10 x 05 (single slides) 4.60 230.00FB 1913-1010-1 A 10 x 10 (single slides) 4.10 410.00FB 1913-2005-1 A 20 x 05 (single slides) 4.30 430.00FA 1913-1003-1 G 10 x 03 (test system) 6.30 189.00FA 1913-1005-1 G 10 x 05 (test system) 6.10 305.00FA 1913-1010-1 G 10 x 10 (test system) 5.50 550.00FA 1913-2005-1 G 20 x 05 (test system) 5.80 580.00FB 1913-1003-1 G 10 x 03 (single slides) 4.70 141.00FB 1913-1005-1 G 10 x 05 (single slides) 4.60 230.00FB 1913-1010-1 G 10 x 10 (single slides) 4.10 410.00FB 1913-2005-1 G 20 x 05 (single slides) 4.30 430.00

FA 1913-1003-2 A endomysium, reticulin oesophagus monkey 10 x 03 (test system) 7.60 228.00FA 1913-1005-2 A endomysium, reticulin small intestine monkey 10 x 05 (test system) 7.30 365.00FA 1913-1010-2 A (2 BIOCHIPs per field) 10 x 10 (test system) 6.60 660.00FA 1913-2005-2 A 20 x 05 (test system) 6.90 690.00FB 1913-1003-2 A 10 x 03 (single slides) 5.70 171.00FB 1913-1005-2 A 10 x 05 (single slides) 5.50 275.00FB 1913-1010-2 A 10 x 10 (single slides) 4.90 490.00FB 1913-2005-2 A 20 x 05 (single slides) 5.20 520.00FA 1913-1003-2 G 10 x 03 (test system) 7.60 228.00FA 1913-1005-2 G 10 x 05 (test system) 7.30 365.00FA 1913-1010-2 G 10 x 10 (test system) 6.60 660.00FA 1913-2005-2 G 20 x 05 (test system) 6.90 690.00FB 1913-1003-2 G 10 x 03 (single slides) 5.70 171.00FB 1913-1005-2 G 10 x 05 (single slides) 5.50 275.00FB 1913-1010-2 G 10 x 10 (single slides) 4.90 490.00FB 1913-2005-2 G 20 x 05 (single slides) 5.20 520.00

FA 1913-1005-6 A “EUROPLUS” 4 BIOCHIPs per field: 10 x 05 (test system) 11.30 565.00FA 1913-1010-6 A endomysium, reticulin small intestine monkey 10 x 10 (test system) 10.20 1,020.00FA 1913-2005-6 A gliadin gliadin BIOCHIPs wheat 20 x 05 (test system) 10.80 1,080.00FB 1913-1005-6 A endomysium, reticulin oesophagus monkey 10 x 05 (single slides) 8.50 425.00FB 1913-1010-6 A endomysium, reticulin liver monkey 10 x 10 (single slides) 7.70 770.00FB 1913-2005-6 A 20 x 05 (single slides) 8.10 810.00FA 1913-1005-6 G 10 x 05 (test system) 11.30 565.00FA 1913-1010-6 G 10 x 10 (test system) 10.20 1,020.00FA 1913-2005-6 G 20 x 05 (test system) 10.80 1,080.00FB 1913-1005-6 G 10 x 05 (single slides) 8.50 425.00FB 1913-1010-6 G 10 x 10 (single slides) 7.70 770.00FB 1913-2005-6 G 20 x 05 (single slides) 8.10 810.00

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Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies

FA 1913-1005-7 A endomysium, reticulin small intestinum monkey 10 x 05 (test system) 9.60 480.00FA 1913-1010-7 A endomysium, reticulin oesophagus monkey 10 x 10 (test system) 8.70 870.00FA 1913-2005-7 A endomysium, reticulin liver monkey 20 x 05 (test system) 9.20 920.00FB 1913-1005-7 A (3 BIOCHIPs per field) 10 x 05 (single slides) 7.20 360.00FB 1913-1010-7 A 10 x 10 (single slides) 6.60 660.00FB 1913-2005-7 A 20 x 05 (single slides) 6.90 690.00FA 1913-1005-7 G 10 x 05 (test system) 9.60 480.00FA 1913-1010-7 G 10 x 10 (test system) 8.70 870.00FA 1913-2005-7 G 20 x 05 (test system) 9.20 920.00FB 1913-1005-7 G 10 x 05 (single slides) 7.20 360.00FB 1913-1010-7 G 10 x 10 (single slides) 6.60 660.00FB 1913-2005-7 G 20 x 05 (single slides) 6.90 690.00

FA 1914-1003 A endomysium liver monkey 10 x 03 (test system) 4.80 144.00FA 1914-1005 A 10 x 05 (test system) 4.60 230.00FA 1914-1010 A 10 x 10 (test system) 4.10 410.00FA 1914-2005 A 20 x 05 (test system) 4.40 440.00FB 1914-1003 A 10 x 03 (single slides) 3.60 108.00FB 1914-1005 A 10 x 05 (single slides) 3.50 175.00FB 1914-1010 A 10 x 10 (single slides) 3.10 310.00FB 1914-2005 A 20 x 05 (single slides) 3.30 330.00FA 1914-1003 G 10 x 03 (test system) 4.80 144.00FA 1914-1005 G 10 x 05 (test system) 4.60 230.00FA 1914-1010 G 10 x 10 (test system) 4.10 410.00FA 1914-2005 G 20 x 05 (test system) 4.40 440.00FB 1914-1003 G 10 x 03 (single slides) 3.60 108.00FB 1914-1005 G 10 x 05 (single slides) 3.50 175.00FB 1914-1010 G 10 x 10 (single slides) 3.10 310.00FB 1914-2005 G 20 x 05 (single slides) 3.30 330.00

FA 1914-1003-1 A “EUROPLUS” 2 BIOCHIPs per field: 10 x 03 (test system) 6.30 189.00FA 1914-1005-1 A endomysium, reticulin liver monkey 10 x 05 (test system) 6.10 305.00FA 1914-1010-1 A gliadin gliadin BIOCHIPs wheat 10 x 10 (test system) 5.50 550.00FA 1914-2005-1 A 20 x 05 (test system) 5.80 580.00FB 1914-1003-1 A 10 x 03 (single slides) 4.70 141.00FB 1914-1005-1 A 10 x 05 (single slides) 4.60 230.00FB 1914-1010-1 A 10 x 10 (single slides) 4.10 410.00FB 1914-2005-1 A 20 x 05 (single slides) 4.30 430.00FA 1914-1003-1 G 10 x 03 (test system) 6.30 189.00FA 1914-1005-1 G 10 x 05 (test system) 6.10 305.00FA 1914-1010-1 G 10 x 10 (test system) 5.50 550.00FA 1914-2005-1 G 20 x 05 (test system) 5.80 580.00FB 1914-1003-1 G 10 x 03 (single slides) 4.70 141.00FB 1914-1005-1 G 10 x 05 (single slides) 4.60 230.00FB 1914-1010-1 G 10 x 10 (single slides) 4.10 410.00FB 1914-2005-1 G 20 x 05 (single slides) 4.30 430.00

Gliadin as single substrate see page 154 (FV 3011).

FA 1914-1003-2 A endomysium, reticulin small intestine monkey 10 x 03 (test system) 5.10 153.00FA 1914-1005-2 A endomysium, reticulin liver monkey 10 x 05 (test system) 4.80 240.00FA 1914-1010-2 A (2 BIOCHIPs per field) 10 x 10 (test system) 4.40 440.00FA 1914-2005-2 A 20 x 05 (test system) 4.60 460.00FB 1914-1003-2 A 10 x 03 (single slides) 3.80 114.00FB 1914-1005-2 A 10 x 05 (single slides) 3.70 185.00FB 1914-1010-2 A 10 x 10 (single slides) 3.30 330.00FB 1914-2005-2 A 20 x 05 (single slides) 3.50 350.00

FA 1914-1003-3 A “EUROPLUS” 3 BIOCHIPs per field: 10 x 03 (test system) 6.60 198.00FA 1914-1005-3 A endomysium liver monkey 10 x 05 (test system) 6.30 315.00FA 1914-1010-3 A endomysium, reticulin small intestine monkey 10 x 10 (test system) 5.70 570.00FA 1914-2005-3 A gliadin gliadin BIOCHIPs wheat 20 x 05 (test system) 6.00 600.00FB 1914-1003-3 A 10 x 03 (single slides) 4.90 147.00FB 1914-1005-3 A 10 x 05 (single slides) 4.70 235.00FB 1914-1010-3 A 10 x 10 (single slides) 4.30 430.00FB 1914-2005-3 A 20 x 05 (single slides) 4.50 450.00FA 1914-1003-3 G 10 x 03 (test system) 6.60 198.00FA 1914-1005-3 G 10 x 05 (test system) 6.30 315.00FA 1914-1010-3 G 10 x 10 (test system) 5.70 570.00FA 1914-2005-3 G 20 x 05 (test system) 6.00 600.00FB 1914-1003-3 G 10 x 03 (single slides) 4.90 147.00FB 1914-1005-3 G 10 x 05 (single slides) 4.70 235.00FB 1914-1010-3 G 10 x 10 (single slides) 4.30 430.00FB 1914-2005-3 G 20 x 05 (single slides) 4.50 450.00

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Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Systemic Autoantibodies

FA 1919-1005 A endomysium umbilical cord human 10 x 05 (test system) 3.10 155.00FA 1919-1010 A 10 x 10 (test system) 2.70 270.00FA 1919-2005 A 20 x 05 (test system) 2.90 290.00FB 1919-1005 A 10 x 05 (single slides) 2.30 115.00FB 1919-1010 A 10 x 10 (single slides) 2.10 210.00FB 1919-2005 A 20 x 05 (single slides) 2.20 220.00

FA 1960-1003 endothelial cells HUVEC human 10 x 03 (test system) 4.80 144.00FA 1960-1005 10 x 05 (test system) 4.60 230.00FA 1960-1010 10 x 10 (test system) 4.10 410.00FA 1960-2005 20 x 05 (test system) 4.40 440.00FB 1960-1003 10 x 03 (single slides) 3.60 108.00FB 1960-1005 10 x 05 (single slides) 3.50 175.00FB 1960-1010 10 x 10 (single slides) 3.10 310.00FB 1960-2005 20 x 05 (single slides) 3.30 330.00

FA 1960-1003-2 endothelial cells musculus iliopsoas monkey 10 x 03 (test system) 7.60 228.00FA 1960-1005-2 endothelial cells HUVEC human 10 x 05 (test system) 7.30 365.00FA 1960-1010-2 (2 BIOCHIPs per field) 10 x 10 (test system) 6.60 660.00FA 1960-2005-2 20 x 05 (test system) 6.90 690.00FB 1960-1003-2 10 x 03 (single slides) 5.70 171.00FB 1960-1005-2 10 x 05 (single slides) 5.50 275.00FB 1960-1010-2 10 x 10 (single slides) 4.90 490.00FB 1960-2005-2 20 x 05 (single slides) 5.20 520.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2050-1003 G Bordetella IgG bacterial Bordetella 10 x 03 (test system) 2.60 78.00FI 2050-1005 G pertussis smear pertussis 10 x 05 (test system) 2.50 125.00FI 2050-1010 G 10 x 10 (test system) 2.30 230.00FI 2050-2005 G 20 x 05 (test system) 2.40 240.00FK 2050-1003 10 x 03 (single slides) 2.00 60.00FK 2050-1005 10 x 05 (single slides) 1.90 95.00FK 2050-1010 10 x 10 (single slides) 1.70 170.00FK 2050-2005 20 x 05 (single slides) 1.80 180.00

FI 2050-1005-1 G Bordetella pertussis IgG bacterial B. pertussis 10 x 05 (test system) 4.00 200.00FI 2050-1010-1 G Bordetella parapertussis smears B. parapertussis 10 x 10 (test system) 3.60 360.00FI 2050-2005-1 G (2 BIOCHIPs per field) 20 x 05 (test system) 3.80 380.00FK 2050-1005-1 10 x 05 (single slides) 3.10 155.00FK 2050-1010-1 10 x 10 (single slides) 2.70 270.00FK 2050-2005-1 20 x 05 (single slides) 2.90 290.00

FI 2055-1003 G Bordetella IgG bacterial Bordetella 10 x 03 (test system) 2.60 78.00FI 2055-1005 G parapertussis smear parapertussis 10 x 05 (test system) 2.50 125.00FI 2055-1010 G 10 x 10 (test system) 2.30 230.00FI 2055-2005 G 20 x 05 (test system) 2.40 240.00FK 2055-1003 10 x 03 (single slides) 2.00 60.00FK 2055-1005 10 x 05 (single slides) 1.90 95.00FK 2055-1010 10 x 10 (single slides) 1.70 170.00FK 2055-2005 20 x 05 (single slides) 1.80 180.00

FI 2070-1005 G * Haemophilus IgG bacterial Haemophilus 10 x 05 (test system) 2.50 125.00FI 2070-1010 G * influenzae smear influenzae 10 x 10 (test system) 2.30 230.00FI 2070-2005 G * 20 x 05 (test system) 2.40 240.00FK 2070-1005 * 10 x 05 (single slides) 1.90 95.00FK 2070-1010 * 10 x 10 (single slides) 1.70 170.00FK 2070-2005 * 20 x 05 (single slides) 1.80 180.00

FI 2080-1005 A Helicobacter IgA bacterial Helicobacter 10 x 05 (test system) 2.50 125.00FI 2080-1010 A pylori smear pylori 10 x 10 (test system) 2.30 230.00FI 2080-2005 A 20 x 05 (test system) 2.40 240.00FI 2080-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2080-1005 G 10 x 05 (test system) 2.50 125.00FI 2080-1010 G 10 x 10 (test system) 2.30 230.00FI 2080-2005 G 20 x 05 (test system) 2.40 240.00FI 2080-1005 M IgM 10 x 05 (test system) 2.50 125.00FI 2080-1010 M 10 x 10 (test system) 2.30 230.00FI 2080-2005 M 20 x 05 (test system) 2.40 240.00FK 2080-1003 10 x 03 (single slides) 2.00 60.00FK 2080-1005 10 x 05 (single slides) 1.90 95.00FK 2080-1010 10 x 10 (single slides) 1.70 170.00FK 2080-2005 20 x 05 (single slides) 1.80 180.00

FI 2090-1005-1 G * Campylobacter jejuni IgG bacterial C. jejuni 10 x 05 (test system) 4.00 200.00FI 2090-1010-1 G * Campylobacter coli smears C. coli 10 x 10 (test system) 3.60 360.00FI 2090-2005-1 G * (2 BIOCHIPs per field) 20 x 05 (test system) 3.80 380.00FK 2090-1005-1 * 10 x 05 (single slides) 3.10 155.00FK 2090-1010-1 * 10 x 10 (single slides) 2.70 270.00FK 2090-2005-1 * 20 x 05 (single slides) 2.90 290.00

FI 2091-1005 G * Campylobacter IgG bacterial Campylobacter 10 x 05 (test system) 2.50 125.00FI 2091-1010 G * jejuni smear jejuni 10 x 10 (test system) 2.30 230.00FI 2091-2005 G * 20 x 05 (test system) 2.40 240.00FK 2091-1005 * 10 x 05 (single slides) 1.90 95.00FK 2091-1010 * 10 x 10 (single slides) 1.70 170.00FK 2091-2005 * 20 x 05 (single slides) 1.80 180.00

FI 2092-1005 G * Campylobacter IgG bacterial Campylobacter 10 x 05 (test system) 2.50 125.00FI 2092-1010 G * coli smear coli 10 x 10 (test system) 2.30 230.00FI 2092-2005 G * 20 x 05 (test system) 2.40 240.00FK 2092-1005 * 10 x 05 (single slides) 1.90 95.00FK 2092-1010 * 10 x 10 (single slides) 1.70 170.00FK 2092-2005 * 20 x 05 (single slides) 1.80 180.00

FI 2101-1005 G * Klebsiella IgG bacterial Klebsiella 10 x 05 (test system) 2.50 125.00FI 2101-1010 G * pneumoniae smear pneumoniae 10 x 10 (test system) 2.30 230.00FI 2101-2005 G * 20 x 05 (test system) 2.40 240.00FK 2101-1005 * 10 x 05 (single slides) 1.90 95.00FK 2101-1010 * 10 x 10 (single slides) 1.70 170.00FK 2101-2005 * 20 x 05 (single slides) 1.80 180.00

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Infe

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2111-1003 G Treponema IgG bacterial smear T. pallidum 10 x 03 (test system) 2.60 78.00FI 2111-1005 G (FTA-ABS) plus FTA sorbent 10 x 05 (test system) 2.50 125.00FI 2111-1010 G 10 x 10 (test system) 2.30 230.00FI 2111-2005 G 20 x 05 (test system) 2.40 240.00FI 2111-1003 M Treponema IgM bacterial smear T. pallidum 10 x 03 (test system) 3.20 96.00FI 2111-1005 M (FTA-ABS) plus FTA sorbent 10 x 05 (test system) 3.10 155.00FI 2111-1010 M plus RF absorbent 10 x 10 (test system) 2.80 280.00FI 2111-2005 M 20 x 05 (test system) 3.00 300.00FK 2111-1003 Treponema bacterial smear T. pallidum 10 x 03 (single slides) 2.00 60.00FK 2111-1005 (FTA-ABS) 10 x 05 (single slides) 1.90 95.00FK 2111-1010 10 x 10 (single slides) 1.70 170.00FK 2111-2005 20 x 05 (single slides) 1.80 180.00

FI 2112-1003 G Treponema IgG bacterial smear T. pallidum 10 x 03 (test system) 4.20 126.00FI 2112-1005 G (FTA-ABS) (2 BIOCHIPs per field) T. phagedenis 10 x 05 (test system) 4.00 200.00FI 2112-1010 G plus FTA sorbent 10 x 10 (test system) 3.60 360.00FI 2112-2005 G 20 x 05 (test system) 3.80 380.00FI 2112-1003 M Treponema IgM bacterial smear T. pallidum 10 x 03 (test system) 4.80 144.00FI 2112-1005 M (FTA-ABS) (2 BIOCHIPs per field) T. phagedenis 10 x 05 (test system) 4.60 230.00FI 2112-1010 M plus FTA sorbent 10 x 10 (test system) 4.10 410.00FI 2112-2005 M plus RF absorbent 20 x 05 (test system) 4.40 440.00FK 2112-1003 Treponema T. pallidum 10 x 03 (single slides) 3.20 96.00FK 2112-1005 (FTA-ABS) bacterial smear T. phagedenis 10 x 05 (single slides) 3.10 155.00FK 2112-1010 10 x 10 (single slides) 2.70 270.00FK 2112-2005 20 x 05 (single slides) 2.90 290.00

FI 2131-1003 G Borrelia IgG bacterial Borrelia 10 x 03 (test system) 1.60 48.00FI 2131-1005 G afzelii smear afzelii 10 x 05 (test system) 1.50 75.00FI 2131-1010 G 10 x 10 (test system) 1.40 140.00FI 2131-2005 G 20 x 05 (test system) 1.50 150.00FI 2131-1003 M IgM 10 x 03 (test system) 1.60 48.00FI 2131-1005 M 10 x 05 (test system) 1.50 75.00FI 2131-1010 M 10 x 10 (test system) 1.40 140.00FI 2131-2005 M 20 x 05 (test system) 1.50 150.00FK 2131-1003 10 x 03 (single slides) 1.20 36.00FK 2131-1005 10 x 05 (single slides) 1.20 60.00FK 2131-1010 10 x 10 (single slides) 1.10 110.00FK 2131-2005 20 x 05 (single slides) 1.10 110.00

FI 2131-1005-1 G “EUROPLUS” IgG 2 BIOCHIPs per field: 10 x 05 (test system) 2.40 120.00FI 2131-1010-1 G Borrelia afzelii bacterial smear B. afzelii 10 x 10 (test system) 2.10 210.00FI 2131-2005-1 G VlsE antigen VlsE-BIOCHPs recombinant 20 x 05 (test system) 2.30 230.00FK 2131-1005-1 10 x 05 (single slides) 1.80 90.00FK 2131-1010-1 10 x 10 (single slides) 1.60 160.00FK 2131-2005-1 20 x 05 (single slides) 1.70 170.00

FI 2131-1005-2 M “EUROPLUS” IgM 2 BIOCHIPs per field: 10 x 05 (test system) 2.40 120.00FI 2131-1010-2 M Borrelia afzelii bacterial smear B. afzelii 10 x 10 (test system) 2.10 210.00FI 2131-2005-2 M OspC antigen OspC-BIOCHIPs B. burgdorferi 20 x 05 (test system) 2.30 230.00FK 2131-1005-2 10 x 05 (single slides) 1.80 90.00FK 2131-1010-2 10 x 10 (single slides) 1.60 160.00FK 2131-2005-2 20 x 05 (single slides) 1.70 170.00

FI 2132-1003 G Borrelia IgG bacterial Borrelia 10 x 03 (test system) 1.60 48.00FI 2132-1005 G burgdorferi smear burgdorferi 10 x 05 (test system) 1.50 75.00FI 2132-1010 G (CH) (CH) 10 x 10 (test system) 1.40 140.00FI 2132-2005 G 20 x 05 (test system) 1.50 150.00FI 2132-1003 M IgM 10 x 03 (test system) 1.60 48.00FI 2132-1005 M 10 x 05 (test system) 1.50 75.00FI 2132-1010 M 10 x 10 (test system) 1.40 140.00FI 2132-2005 M 20 x 05 (test system) 1.50 150.00FK 2132-1003 10 x 03 (single slides) 1.20 36.00FK 2132-1005 10 x 05 (single slides) 1.20 60.00FK 2132-1010 10 x 10 (single slides) 1.10 110.00FK 2132-2005 20 x 05 (single slides) 1.10 110.00

FI 2133-1003 G Borrelia IgG bacterial Borrelia 10 x 03 (test system) 1.60 48.00FI 2133-1005 G burgdorferi smear burgdorferi 10 x 05 (test system) 1.50 75.00FI 2133-1010 G (USA) (USA) 10 x 10 (test system) 1.40 140.00FI 2133-2005 G 20 x 05 (test system) 1.50 150.00FI 2133-1003 M IgM 10 x 03 (test system) 1.60 48.00FI 2133-1005 M 10 x 05 (test system) 1.50 75.00FI 2133-1010 M 10 x 10 (test system) 1.40 140.00FI 2133-2005 M 20 x 05 (test system) 1.50 150.00FK 2133-1003 10 x 03 (single slides) 1.20 36.00FK 2133-1005 10 x 05 (single slides) 1.20 60.00FK 2133-1010 10 x 10 (single slides) 1.10 110.00FK 2133-2005 20 x 05 (single slides) 1.10 110.00

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

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rIn

fecti

ou

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ero

log

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2134-1005 G Borrelia IgG bacterial Borrelia 10 x 05 (test system) 1.50 75.00FI 2134-1010 G garinii smear garinii 10 x 10 (test system) 1.40 140.00FI 2134-2005 G 20 x 05 (test system) 1.50 150.00FI 2134-1005 M IgM 10 x 05 (test system) 1.50 75.00FI 2134-1010 M 10 x 10 (test system) 1.40 140.00FI 2134-2005 M 20 x 05 (test system) 1.50 150.00FK 2134-1005 10 x 05 (single slides) 1.20 60.00FK 2134-1010 10 x 10 (single slides) 1.10 110.00FK 2134-2005 20 x 05 (single slides) 1.10 110.00

FI 2136-1005 G Borrelia afzelii IgG bacterial B. afzelii 10 x 05 (test system) 2.40 120.00FI 2136-1010 G Borrelia burgdorferi (USA) smears B. burgdorferi (USA) 10 x 10 (test system) 2.10 210.00FI 2136-2005 G (2 BIOCHIPs per field) 20 x 05 (test system) 2.30 230.00FI 2136-1005 M IgM 10 x 05 (test system) 2.40 120.00FI 2136-1010 M 10 x 10 (test system) 2.10 210.00FI 2136-2005 M 20 x 05 (test system) 2.30 230.00FK 2136-1005 10 x 05 (single slides) 1.80 90.00FK 2136-1010 10 x 10 (single slides) 1.60 160.00FK 2136-2005 20 x 05 (single slides) 1.70 170.00

FI 2136-1005-1 G “EUROPLUS” IgG 4 BIOCHIPs per field: 10 x 05 (test system) 3.10 155.00FI 2136-1010-1 G Borrelia afzelii bacterial smear B. afzelii 10 x 10 (test system) 2.80 280.00FI 2136-2005-1 G Borrelia burgdorferi (USA) bacterial smear B. burgdorferi (USA) 20 x 05 (test system) 3.00 300.00FI 2136-1005-1 M OspC antigen IgM OspC-BIOCHIPs B. burgdorferi 10 x 05 (test system) 3.10 155.00FI 2136-1010-1 M VlsE antigen VlsE-BIOCHPs recombinant 10 x 10 (test system) 2.80 280.00FI 2136-2005-1 M 20 x 05 (test system) 3.00 300.00FK 2136-1005-1 10 x 05 (single slides) 2.30 115.00FK 2136-1010-1 10 x 10 (single slides) 2.10 210.00FK 2136-2005-1 20 x 05 (single slides) 2.20 220.00

FI 2137-1003 G Borrelia afzelii IgG bacterial B. afzelii 10 x 03 (test system) 2.50 75.00FI 2137-1005 G Borrelia burgdorferi (CH) smears B. burgdorferi (CH) 10 x 05 (test system) 2.40 120.00FI 2137-1010 G (2 BIOCHIPs per field) 10 x 10 (test system) 2.10 210.00FI 2137-2005 G 20 x 05 (test system) 2.30 230.00FI 2137-1003 M IgM 10 x 03 (test system) 2.50 75.00FI 2137-1005 M 10 x 05 (test system) 2.40 120.00FI 2137-1010 M 10 x 10 (test system) 2.10 210.00FI 2137-2005 M 20 x 05 (test system) 2.30 230.00FK 2137-1003 10 x 03 (single slides) 1.90 57.00FK 2137-1005 10 x 05 (single slides) 1.80 90.00FK 2137-1010 10 x 10 (single slides) 1.60 160.00FK 2137-2005 20 x 05 (single slides) 1.70 170.00

FI 2138-1005 G Borrelia afzelii IgG bacterial B. afzelii 10 x 05 (test system) 3.10 155.00FI 2138-2005 G Borrelia burgdorferi (USA) smears B. burgdorferi (USA) 20 x 05 (test system) 3.00 300.00FI 2138-1005 M Borrelia garinii IgM (3 BIOCHIPs per field) B. garinii 10 x 05 (test system) 3.10 155.00FI 2138-2005 M 20 x 05 (test system) 3.00 300.00FK 2138-1005 10 x 05 (single slides) 2.30 115.00FK 2138-2005 20 x 05 (single slides) 2.20 220.00

FI 2138-1005-2 G Borrelia afzelii IgG bacterial B. afzelii 10 x 05 (test system) 3.90 195.00FI 2138-1010-2 G Borrelia burgdorferi (CH) smears B. burgdorferi (CH) 10 x 10 (test system) 3.50 350.00FI 2138-2005-2 G Borrelia burgdorferi (USA) (4 BIOCHIPs per field) B. burgd. (USA) 20 x 05 (test system) 3.70 370.00FI 2138-1005-2 M Borrelia garinii IgM B. garinii 10 x 05 (test system) 3.90 195.00FI 2138-1010-2 M 10 x 10 (test system) 3.50 350.00FI 2138-2005-2 M 20 x 05 (test system) 3.70 370.00FK 2138-1005-2 10 x 05 (single slides) 3.00 150.00FK 2138-1010-2 10 x 10 (single slides) 2.60 260.00FK 2138-2005-2 20 x 05 (single slides) 2.80 280.00

FI 2141-1005 G * Listeria IgG bacterial Listeria 10 x 05 (test system) 1.50 75.00FI 2141-1010 G * monocytogenes smear monocytogenes 10 x 10 (test system) 1.40 140.00FI 2141-2005 G * 1/2a 1/2a 20 x 05 (test system) 1.50 150.00FK 2141-1005 * 10 x 05 (single slides) 1.20 60.00FK 2141-1010 * 10 x 10 (single slides) 1.10 110.00FK 2141-2005 * 20 x 05 (single slides) 1.10 110.00

FI 2141-1003-1 G * Listeria IgG bacterial Listeria 10 x 03 (test system) 2.50 75.00FI 2141-1005-1 G * monocytogenes smears monocytogenes 10 x 05 (test system) 2.40 120.00FI 2141-1010-1 G * 1/2a and 4b (2 BIOCHIPs per field) 1/2a and 4b 10 x 10 (test system) 2.10 210.00FI 2141-2005-1 G * 20 x 05 (test system) 2.30 230.00FK 2141-1003-1 * 10 x 03 (single slides) 1.90 57.00FK 2141-1005-1 * 10 x 05 (single slides) 1.80 90.00FK 2141-1010-1 * 10 x 10 (single slides) 1.60 160.00FK 2141-2005-1 * 20 x 05 (single slides) 1.70 170.00

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

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sce

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Infe

ctio

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ero

log

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2144-1005 G * Listeria IgG bacterial Listeria 10 x 05 (test system) 1.50 75.00FI 2144-1010 G * monocytogenes smear monocytogenes 10 x 10 (test system) 1.40 140.00FI 2144-2005 G * 4b 4b 20 x 05 (test system) 1.50 150.00FK 2144-1005 * 10 x 05 (single slides) 1.20 60.00FK 2144-1010 * 10 x 10 (single slides) 1.10 110.00FK 2144-2005 * 20 x 05 (single slides) 1.10 110.00

FI 2150-1001 P “BIOCHIP Sequence IgAGM bacterial Legionella 10 x 01 (test system) 6.50 65.00FI 2150-2001 P Legionella pneumophila” smears pneumophila 20 x 01 (test system) 6.20 124.00FI 2150-5001 P serotypes 1 - 14 (1 BIOCHIP 50 x 01 (test system) 6.00 300.00FK 2150-1001 per serotype) 10 x 01 (single slides) 4.90 49.00FK 2150-2001 20 x 01 (single slides) 4.60 92.00FK 2150-5001 50 x 01 (single slides) 4.50 225.00

FI 2150-1001-1 P “BIOCHIP Sequence Legionella” IgAGM bacterial smears L. pneumophila 10 x 01 (test system) 11.70 117.00FI 2150-2001-1 P Legionella pneumophila 1 - 14 (1 BIOCHIP per L. jordanis 20 x 01 (test system) 11.10 222.00FI 2150-5001-1 P L. jordanis, L. bozemanii, serotype or species) L. bozemanii 50 x 01 (test system) 10.80 540.00FK 2150-1001-1 L. gormanii, L. micdadei, L. gormanii 10 x 01 (single slides) 8.80 88.00FK 2150-2001-1 L. dumoffii, L. longbeachae L. micdadei 20 x 01 (single slides) 8.40 168.00FK 2150-5001-1 L. dumoffii 50 x 01 (single slides) 8.10 405.00

L. longbeachae

FI 2150-1005-3 P Legionella pneumophila IgAGM bacterial Legionella 10 x 05 (test system) 3.90 195.00FI 2150-1010-3 P mixture 1-4-6-8 smears pneumophila 10 x 10 (test system) 3.50 350.00FI 2150-2005-3 P mixture 2-3-5-7 (4 BIOCHIPs per field) 20 x 05 (test system) 3.70 370.00FK 2150-1005-3 mixture 9-11-13 10 x 05 (single slides) 3.00 150.00FK 2150-1010-3 mixture 10-12-14 10 x 10 (single slides) 2.60 260.00FK 2150-2005-3 20 x 05 (single slides) 2.80 280.00

FI 215b-1003 P Legionella pneumophila IgAGM bacterial Legionella 10 x 03 (test system) 1.60 48.00FI 215b-1005 P mixture 1-4-6-8 smear pneumophila 10 x 05 (test system) 1.50 75.00FI 215b-1010 P 10 x 10 (test system) 1.40 140.00FI 215b-2005 P 20 x 05 (test system) 1.50 150.00FK 215b-1003 10 x 03 (single slides) 1.20 36.00FK 215b-1005 10 x 05 (single slides) 1.20 60.00FK 215b-1010 10 x 10 (single slides) 1.10 110.00FK 215b-2005 20 x 05 (single slides) 1.10 110.00

FI 215b-1003-1 P Legionella pneumophila IgAGM bacterial Legionella 10 x 03 (test system) 2.50 75.00FI 215b-1005-1 P mixture 1-4-6-8 smears pneumophila 10 x 05 (test system) 2.40 120.00FI 215b-1010-1 P mixture 2-3-5-7 (2 BIOCHIPs per field) 10 x 10 (test system) 2.10 210.00FI 215b-2005-1 P 20 x 05 (test system) 2.30 230.00FK 215b-1003-1 10 x 03 (single slides) 1.90 57.00FK 215b-1005-1 10 x 05 (single slides) 1.80 90.00FK 215b-1010-1 10 x 10 (single slides) 1.60 160.00FK 215b-2005-1 20 x 05 (single slides) 1.70 170.00

FI 215d-1005 P Legionella pneumophila IgAGM bacterial Legionella 10 x 05 (test system) 1.50 75.00FI 215d-1010 P mixture 2-3-5-7 smear pneumophila 10 x 10 (test system) 1.40 140.00FI 215d-2005 P 20 x 05 (test system) 1.50 150.00FK 215d-1005 10 x 05 (single slides) 1.20 60.00FK 215d-1010 10 x 10 (single slides) 1.10 110.00FK 215d-2005 20 x 05 (single slides) 1.10 110.00

FI 215f-1005 P Legionella pneumophila IgAGM bacterial Legionella 10 x 05 (test system) 1.50 75.00FI 215f-1010 P mixture 9-11-13 smear pneumophila 10 x 10 (test system) 1.40 140.00FI 215f-2005 P 20 x 05 (test system) 1.50 150.00FK 215f-1005 10 x 05 (single slides) 1.20 60.00FK 215f-1010 10 x 10 (single slides) 1.10 110.00FK 215f-2005 20 x 05 (single slides) 1.10 110.00

FI 215h-1005 P Legionella pneumophila IgAGM bacterial Legionella 10 x 05 (test system) 1.50 75.00FI 215h-1010 P mixture 10-12-14 smear pneumophila 10 x 10 (test system) 1.40 140.00FI 215h-2005 P 20 x 05 (test system) 1.50 150.00FK 215h-1005 10 x 05 (single slides) 1.20 60.00FK 215h-1010 10 x 10 (single slides) 1.10 110.00FK 215h-2005 20 x 05 (single slides) 1.10 110.00

FI 2151-1005 P Legionella pneumophila IgAGM bacterial Legionella 10 x 05 (test system) 1.50 75.00FI 2151-1010 P serotype 1 smear pneumophila 10 x 10 (test system) 1.40 140.00FI 2151-2005 P 20 x 05 (test system) 1.50 150.00FK 2151-1005 10 x 05 (single slides) 1.20 60.00FK 2151-1010 10 x 10 (single slides) 1.10 110.00FK 2151-2005 20 x 05 (single slides) 1.10 110.00

Slides with any one of the Legionella pneumophila serotypes 2 (FK 2152) to 14 (FK 2164) can be delivered as well.

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rIn

fecti

ou

s S

ero

log

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2168-1005 G Legionella IgG bacterial Legionella 10 x 05 (test system) 1.50 75.00FI 2168-1010 G longbeachae smear longbeachae 10 x 10 (test system) 1.40 140.00FI 2168-2005 G 20 x 05 (test system) 1.50 150.00FI 2168-1005 P IgAGM 10 x 05 (test system) 1.50 75.00FI 2168-1010 P 10 x 10 (test system) 1.40 140.00FI 2168-2005 P 20 x 05 (test system) 1.50 150.00FK 2168-1005 10 x 05 (single slides) 1.20 60.00FK 2168-1010 10 x 10 (single slides) 1.10 110.00FK 2168-2005 20 x 05 (single slides) 1.10 110.00

FI 216f-1005-1 P “Mosaic Legionella non-pneumophila”IgAGM 10 x 05 (test system) 5.90 295.00FI 216f-2005-1 P Legionella jordanis 6 BIOCHIPs per field: L. jordanis 20 x 05 (test system) 5.60 560.00FK 216f-1005-1 Legionella bozemanii bacterial L. bozemanii 10 x 05 (single slides) 4.40 220.00FK 216f-2005-1 Legionella gormanii smears L. gormanii 20 x 05 (single slides) 4.20 420.00

Legionella micdadei L. micdadeiLegionella dumoffii L. dumoffii

Legionella longbeachae L. longbeachae

Slides with the Legionella non-pneumophila species jordanis (FK 2165), gormanii (FK 2166), dumoffii (FK 2167), micdadei (FK 2169) or bozemanii (FK 216a)can be delivered as well.

FI 2173-1003 G * Yersinia IgG bacterial Yersinia 10 x 03 (test system) 2.60 78.00FI 2173-1005 G * enterocolitica smear enterocolitica 10 x 05 (test system) 2.50 125.00FI 2173-1010 G * O:3 10 x 10 (test system) 2.30 230.00FI 2173-2005 G * (for diagnosing various 20 x 05 (test system) 2.40 240.00FK 2173-1003 * forms of arthritis) 10 x 03 (single slides) 2.00 60.00FK 2173-1005 * 10 x 05 (single slides) 1.90 95.00FK 2173-1010 * 10 x 10 (single slides) 1.70 170.00FK 2173-2005 * 20 x 05 (single slides) 1.80 180.00

Slides for diagnosis of various forms of arthritis with any one of the Yersinia enterocolitica types O:4 (FK 2174), O:6 (FK 2176) or O:9 (FK 2179) can bedelivered as well.

FI 2173-1005-1 G * “BIOCHIP Mosaic” IgG 4 BIOCHIPs per field: 10 x 05 (test system) 6.80 340.00FI 2173-1010-1 G * Yersinia enterocolitica bacterial Yersinia 10 x 10 (test system) 6.10 610.00FI 2173-2005-1 G * O:3, O:4, O:6, O:9 smears enterocolitica 20 x 05 (test system) 6.40 640.00FK 2173-1005-1 * (for diagnosing various 10 x 05 (single slides) 5.10 255.00FK 2173-1010-1 * forms of arthritis) 10 x 10 (single slides) 4.60 460.00FK 2173-2005-1 * 20 x 05 (single slides) 4.80 480.00

FI 2191-1003 A Chlamydia IgA infected cells EU 40 10 x 03 (test system) 3.20 96.00FI 2191-1005 A trachomatis 10 x 05 (test system) 3.10 155.00FI 2191-1010 A 10 x 10 (test system) 2.70 270.00FI 2191-2005 A 20 x 05 (test system) 2.90 290.00FI 2191-1003 G IgG 10 x 03 (test system) 3.20 96.00FI 2191-1005 G 10 x 05 (test system) 3.10 155.00FI 2191-1010 G 10 x 10 (test system) 2.70 270.00FI 2191-2005 G 20 x 05 (test system) 2.90 290.00FI 2191-1003 M IgM 10 x 03 (test system) 3.20 96.00FI 2191-1005 M 10 x 05 (test system) 3.10 155.00FI 2191-1010 M 10 x 10 (test system) 2.70 270.00FI 2191-2005 M 20 x 05 (test system) 2.90 290.00FK 2191-1003 10 x 03 (single slides) 2.40 72.00FK 2191-1005 10 x 05 (single slides) 2.30 115.00FK 2191-1010 10 x 10 (single slides) 2.10 210.00FK 2191-2005 20 x 05 (single slides) 2.20 220.00

FI 2191-1003-2 A Chlamydia trachomatis IgA infected EU 40 10 x 03 (test system) 5.10 153.00FI 2191-1005-2 A Chlamydia pneumoniae cells EU 38 10 x 05 (test system) 4.80 240.00FI 2191-1010-2 A (2 BIOCHIPs per field) 10 x 10 (test system) 4.40 440.00FI 2191-2005-2 A 20 x 05 (test system) 4.60 460.00FI 2191-1003-2 G IgG 10 x 03 (test system) 5.10 153.00FI 2191-1005-2 G 10 x 05 (test system) 4.80 240.00FI 2191-1010-2 G 10 x 10 (test system) 4.40 440.00FI 2191-2005-2 G 20 x 05 (test system) 4.60 460.00FI 2191-1003-2 M IgM 10 x 03 (test system) 5.10 153.00FI 2191-1005-2 M 10 x 05 (test system) 4.80 240.00FI 2191-1010-2 M 10 x 10 (test system) 4.40 440.00FI 2191-2005-2 M 20 x 05 (test system) 4.60 460.00FK 2191-1003-2 10 x 03 (single slides) 3.80 114.00FK 2191-1005-2 10 x 05 (single slides) 3.70 185.00FK 2191-1010-2 10 x 10 (single slides) 3.30 330.00FK 2191-2005-2 20 x 05 (single slides) 3.50 350.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2191-1005-3 A * “anti-Chlamydia MIF” IgA infected EU 40 10 x 05 (test system) 6.60 330.00FI 2191-1010-3 A * Chlamydia trachomatis (elementary bodies) EU 40 10 x 10 (test system) 6.00 600.00FI 2191-2005-3 A * Chlamydia pneumoniae and non-infected cells EU 40 20 x 05 (test system) 6.30 630.00FI 2191-1005-3 G * Chlamydia psittaci IgG (4 BIOCHIPs per field) 10 x 05 (test system) 6.60 330.00FI 2191-1010-3 G * 10 x 10 (test system) 6.00 600.00FI 2191-2005-3 G * 20 x 05 (test system) 6.30 630.00FK 2191-1005-3 * 10 x 05 (single slides) 5.00 250.00FK 2191-1010-3 * 10 x 10 (single slides) 4.50 450.00FK 2191-2005-3 * 20 x 05 (single slides) 4.70 470.00

FI 2192-1003 A Chlamydia IgA infected EU 38 10 x 03 (test system) 3.20 96.00FI 2192-1005 A pneumoniae cells 10 x 05 (test system) 3.10 155.00FI 2192-1010 A 10 x 10 (test system) 2.70 270.00FI 2192-2005 A 20 x 05 (test system) 2.90 290.00FI 2192-1003 G IgG 10 x 03 (test system) 3.20 96.00FI 2192-1005 G 10 x 05 (test system) 3.10 155.00FI 2192-1010 G 10 x 10 (test system) 2.70 270.00FI 2192-2005 G 20 x 05 (test system) 2.90 290.00FI 2192-1003 M IgM 10 x 03 (test system) 3.20 96.00FI 2192-1005 M 10 x 05 (test system) 3.10 155.00FI 2192-1010 M 10 x 10 (test system) 2.70 270.00FI 2192-2005 M 20 x 05 (test system) 2.90 290.00FK 2192-1003 10 x 03 (single slides) 2.40 72.00FK 2192-1005 10 x 05 (single slides) 2.30 115.00FK 2192-1010 10 x 10 (single slides) 2.10 210.00FK 2192-2005 20 x 05 (single slides) 2.20 220.00

FI 219b-1003 G Bartonella IgG infected EU 70 10 x 03 (test system) 2.60 78.00FI 219b-1005 G henselae cells 10 x 05 (test system) 2.50 125.00FI 219b-1010 G 10 x 10 (test system) 2.30 230.00FI 219b-2005 G 20 x 05 (test system) 2.40 240.00FK 219b-1003 G 10 x 03 (single slides) 2.00 60.00FK 219b-1005 G 10 x 05 (single slides) 1.90 95.00FK 219b-1010 G 10 x 10 (single slides) 1.70 170.00FK 219b-2005 G 20 x 05 (single slides) 1.80 180.00FI 219b-1003 M IgM infected and non- EU 70 10 x 03 (test system) 2.60 78.00FI 219b-1005 M infected cells 10 x 05 (test system) 2.50 125.00FI 219b-1010 M (2 BIOCHIPs per field) 10 x 10 (test system) 2.30 230.00FI 219b-2005 M 20 x 05 (test system) 2.40 240.00FK 219b-1003 M 10 x 03 (single slides) 2.00 60.00FK 219b-1005 M 10 x 05 (single slides) 1.90 95.00FK 219b-1010 M 10 x 10 (single slides) 1.70 170.00FK 219b-2005 M 20 x 05 (single slides) 1.80 180.00

FI 219b-1005-1 G Bartonella henselae IgG infected cells EU 70 10 x 05 (test system) 4.00 200.00FI 219b-1010-1 G Bartonella quintana infected cells EU 70 10 x 10 (test system) 3.60 360.00FI 219b-2005-1 G (2 BIOCHIPs per field) 20 x 05 (test system) 3.80 380.00FK 219b-1005-1 G 10 x 05 (single slides) 3.10 155.00FK 219b-1010-1 G 10 x 10 (single slides) 2.70 270.00FK 219b-2005-1 G 20 x 05 (single slides) 2.90 290.00FI 219b-1005-1 M IgM infected and non- EU 70 10 x 05 (test system) 4.00 200.00FI 219b-1010-1 M infected cells EU 38 10 x 10 (test system) 3.60 360.00FI 219b-2005-1 M (4 BIOCHIPs per field) 20 x 05 (test system) 3.80 380.00FK 219b-1005-1 M 10 x 05 (single slides) 3.10 155.00FK 219b-1010-1 M 10 x 10 (single slides) 2.70 270.00FK 219b-2005-1 M 20 x 05 (single slides) 2.90 290.00

FI 219d-1005 G Bartonella IgG infected EU 70 10 x 05 (test system) 2.50 125.00FI 219d-1010 G quintana cells 10 x 10 (test system) 2.30 230.00FI 219d-2005 G 20 x 05 (test system) 2.40 240.00FK 219d-1005 G 10 x 05 (single slides) 1.90 95.00FK 219d-1010 G 10 x 10 (single slides) 1.70 170.00FK 219d-2005 G 20 x 05 (single slides) 1.80 180.00FI 219d-1005 M IgM infected and non- EU 38 10 x 05 (test system) 2.50 125.00FI 219d-1010 M infected cells 10 x 10 (test system) 2.30 230.00FI 219d-2005 M (2 BIOCHIPs per field) 20 x 05 (test system) 2.40 240.00FK 219d-1005 M 10 x 05 (single slides) 1.90 95.00FK 219d-1010 M 10 x 10 (single slides) 1.70 170.00FK 219d-2005 M 20 x 05 (single slides) 1.80 180.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2201-1005 A Mycoplasma IgA infected and non- EU 38 10 x 05 (test system) 2.50 125.00FI 2201-1010 A hominis infected cells 10 x 10 (test system) 2.20 220.00FI 2201-2005 A (2 BIOCHIPs per field) 20 x 05 (test system) 2.40 240.00FI 2201-1005 G IgG 10 x 05 (test system) 2.50 125.00FI 2201-1010 G 10 x 10 (test system) 2.20 220.00FI 2201-2005 G 20 x 05 (test system) 2.40 240.00FI 2201-1005 M IgM 10 x 05 (test system) 2.50 125.00FI 2201-1010 M 10 x 10 (test system) 2.20 220.00FI 2201-2005 M 20 x 05 (test system) 2.40 240.00FK 2201-1005 10 x 05 (single slides) 1.90 95.00FK 2201-1010 10 x 10 (single slides) 1.70 170.00FK 2201-2005 20 x 05 (single slides) 1.80 180.00

FI 2201-1005-1 A Mycoplasma hominis IgA infected cells EU 38 10 x 05 (test system) 4.00 200.00FI 2201-1010-1 A Ureaplasma urealyticum infected cells EU 38 10 x 10 (test system) 3.60 360.00FI 2201-2005-1 A non-infected cells EU 38 20 x 05 (test system) 3.80 380.00FI 2201-1005-1 G IgG (3 BIOCHIPs per field) 10 x 05 (test system) 5.30 265.00FI 2201-1010-1 G 10 x 10 (test system) 4.70 470.00FI 2201-2005-1 G 20 x 05 (test system) 5.00 500.00FI 2201-1005-1 M IgM 10 x 05 (test system) 5.30 265.00FI 2201-1010-1 M 10 x 10 (test system) 4.70 470.00FI 2201-2005-1 M 20 x 05 (test system) 5.00 500.00FK 2201-1005-1 10 x 05 (single slides) 3.00 150.00FK 2201-1010-1 10 x 10 (single slides) 2.70 270.00FK 2201-2005-1 20 x 05 (single slides) 2.90 290.00

FI 2202-1003 A Mycoplasma IgA infected and non- EU 38 10 x 03 (test system) 2.60 78.00FI 2202-1005 A pneumoniae infected cells 10 x 05 (test system) 2.50 125.00FI 2202-1010 A (2 BIOCHIPs per field) 10 x 10 (test system) 2.20 220.00FI 2202-2005 A 20 x 05 (test system) 2.40 240.00FI 2202-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2202-1005 G 10 x 05 (test system) 2.50 125.00FI 2202-1010 G 10 x 10 (test system) 2.20 220.00FI 2202-2005 G 20 x 05 (test system) 2.40 240.00FI 2202-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2202-1005 M 10 x 05 (test system) 2.50 125.00FI 2202-1010 M 10 x 10 (test system) 2.20 220.00FI 2202-2005 M 20 x 05 (test system) 2.40 240.00FK 2202-1003 10 x 03 (single slides) 2.00 60.00FK 2202-1005 10 x 05 (single slides) 1.90 95.00FK 2202-1010 10 x 10 (single slides) 1.70 170.00FK 2202-2005 20 x 05 (single slides) 1.80 180.00

FI 2205-1005 A Ureaplasma IgA infected and non- EU 38 10 x 05 (test system) 2.50 125.00FI 2205-1010 A urealyticum infected cells 10 x 10 (test system) 2.20 220.00FI 2205-2005 A (2 BIOCHIPs per field) 20 x 05 (test system) 2.40 240.00FI 2205-1005 G IgG 10 x 05 (test system) 2.50 125.00FI 2205-1010 G 10 x 10 (test system) 2.20 220.00FI 2205-2005 G 20 x 05 (test system) 2.40 240.00FI 2205-1005 M IgM 10 x 05 (test system) 2.50 125.00FI 2205-1010 M 10 x 10 (test system) 2.20 220.00FI 2205-2005 M 20 x 05 (test system) 2.40 240.00FK 2205-1005 10 x 05 (single slides) 1.90 95.00FK 2205-1010 10 x 10 (single slides) 1.70 170.00FK 2205-2005 20 x 05 (single slides) 1.80 180.00

FI 2231-1003 A Leishmania donovani IgA protozoan Leishmania 10 x 03 (test system) 2.60 78.00FI 2231-1005 A (promastigot) smear donovani 10 x 05 (test system) 2.50 125.00FI 2231-1010 A 10 x 10 (test system) 2.30 230.00FI 2231-2005 A 20 x 05 (test system) 2.40 240.00FI 2231-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2231-1005 G 10 x 05 (test system) 2.50 125.00FI 2231-1010 G 10 x 10 (test system) 2.30 230.00FI 2231-2005 G 20 x 05 (test system) 2.40 240.00FI 2231-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2231-1005 M 10 x 05 (test system) 2.50 125.00FI 2231-1010 M 10 x 10 (test system) 2.30 230.00FI 2231-2005 M 20 x 05 (test system) 2.40 240.00FK 2231-1003 10 x 03 (single slides) 2.00 60.00FK 2231-1005 10 x 05 (single slides) 1.90 95.00FK 2231-1010 10 x 10 (single slides) 1.70 170.00FK 2231-2005 20 x 05 (single slides) 1.80 180.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2260-1005-1 G “EUROPLUS” IgG 2 BIOCHIPs per field: 10 x 05 (test system) 8.10 405.00FI 2260-1010-1 G Plasmodium falciparum rec. antigens Plasmodium 10 x 10 (test system) 7.30 730.00FI 2260-2010-1 G HRP-2 + MSP-2 falciparum 20 x 10 (test system) 6.90 1,380.00FK 2260-1005-1 Plasmodium vivax rec. antigens Plasmodium 10 x 05 (single slides) 6.10 305.00FK 2260-1010-1 MSP + CSP vivax 10 x 10 (single slides) 5.50 550.00FK 2260-2010-1 20 x 10 (single slides) 5.20 1,040.00

FI 2320-1003 A Echinococcus IgA frozen Echinococcus 10 x 03 (test system) 2.60 78.00FI 2320-1005 A granulosus sections larvae 10 x 05 (test system) 2.50 125.00FI 2320-1010 A 10 x 10 (test system) 2.30 230.00FI 2320-2005 A 20 x 05 (test system) 2.40 240.00FI 2320-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2320-1005 G 10 x 05 (test system) 2.50 125.00FI 2320-1010 G 10 x 10 (test system) 2.30 230.00FI 2320-2005 G 20 x 05 (test system) 2.40 240.00FI 2320-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2320-1005 M 10 x 05 (test system) 2.50 125.00FI 2320-1010 M 10 x 10 (test system) 2.30 230.00FI 2320-2005 M 20 x 05 (test system) 2.40 240.00FK 2320-1003 10 x 03 (single slides) 2.00 60.00FK 2320-1005 10 x 05 (single slides) 1.90 95.00FK 2320-1010 10 x 10 (single slides) 1.70 170.00FK 2320-2005 20 x 05 (single slides) 1.80 180.00

FI 2410-1003 A * Toxoplasma IgA protozoan Toxoplasma 10 x 03 (test system) 1.60 48.00FI 2410-1005 A * gondii smear gondii 10 x 05 (test system) 1.50 75.00FI 2410-1010 A * 10 x 10 (test system) 1.40 140.00FI 2410-2005 A * 20 x 05 (test system) 1.50 150.00FI 2410-1003 G IgG 10 x 03 (test system) 1.60 48.00FI 2410-1005 G 10 x 05 (test system) 1.50 75.00FI 2410-1010 G 10 x 10 (test system) 1.40 140.00FI 2410-2005 G 20 x 05 (test system) 1.50 150.00FI 2410-1003 M IgM 10 x 03 (test system) 1.60 48.00FI 2410-1005 M 10 x 05 (test system) 1.50 75.00FI 2410-1010 M 10 x 10 (test system) 1.40 140.00FI 2410-2005 M 20 x 05 (test system) 1.50 150.00FI 2410-1003 X (avidity test) 10 x 03 (test system) 1.60 48.00FI 2410-1005 X 10 x 05 (test system) 1.50 75.00FI 2410-1010 X 10 x 10 (test system) 1.40 140.00FI 2410-2005 X 20 x 05 (test system) 1.50 150.00FK 2410-1003 10 x 03 (single slides) 1.20 36.00FK 2410-1005 10 x 05 (single slides) 1.20 60.00FK 2410-1010 10 x 10 (single slides) 1.10 110.00FK 2410-2005 20 x 05 (single slides) 1.10 110.00

FI 2410-1003-3 G “TO.R.C.H. Profile” IgG 4 BIOCHIPs per field: 10 x 03 (test system) 6.30 189.00FI 2410-1005-3 G Toxoplasma gondii protozoan smear T. gondii 10 x 05 (test system) 6.10 305.00FI 2410-1010-3 G Rubella virus infected cells EU 13 10 x 10 (test system) 5.50 550.00FI 2410-2005-3 G Cytomegalovirus infected cells EU 168 20 x 05 (test system) 5.80 580.00FK 2410-1003-3 HSV mixture (1+2) infected cells EU 38 10 x 03 (single slides) 4.70 141.00FK 2410-1005-3 10 x 05 (single slides) 4.60 230.00FK 2410-1010-3 10 x 10 (single slides) 4.10 410.00FK 2410-2005-3 20 x 05 (single slides) 4.30 430.00

FI 2511-1005 G * HIV-1 IgG infected and non- EU 61 10 x 05 (test system) 2.50 125.00FI 2511-1010 G * infected cells 10 x 10 (test system) 2.20 220.00FI 2511-2005 G * (2 BIOCHIPs per field) 20 x 05 (test system) 2.40 240.00FK 2511-1005 * 10 x 05 (single slides) 1.90 95.00FK 2511-1010 * 10 x 10 (single slides) 1.70 170.00FK 2511-2005 * 20 x 05 (single slides) 1.80 180.00

FI 2511-1005-1 G * “BIOCHIP Mosaic” IgG 4 BIOCHIPs per field: 10 x 05 (test system) 4.30 215.00FI 2511-2005-1 G * HIV-1/HIV-2 infected and non- EU 61, EU 62 20 x 05 (test system) 4.10 410.00FK 2511-1005-1 * infected cells 10 x 05 (single slides) 3.30 165.00FK 2511-2005-1 * 20 x 05 (single slides) 3.10 310.00

FI 2512-1005 G * HIV-2 IgG infected and EU 62 10 x 05 (test system) 2.50 125.00FI 2512-1010 G * non-infected cells 10 x 10 (test system) 2.20 220.00FI 2512-2005 G * (2 BIOCHIPs per field) 20 x 05 (test system) 2.40 240.00FK 2512-1005 * 10 x 05 (single slides) 1.90 95.00FK 2512-1010 * 10 x 10 (single slides) 1.70 170.00FK 2512-2005 * 20 x 05 (single slides) 1.80 180.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

FI 2531-1003 G Herpes simplex virus 1 IgG infected EU 38 10 x 03 (test system) 2.60 78.00FI 2531-1005 G (HSV-1) cells 10 x 05 (test system) 2.50 125.00FI 2531-1010 G 10 x 10 (test system) 2.30 230.00FI 2531-2005 G 20 x 05 (test system) 2.40 240.00FI 2531-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2531-1005 M 10 x 05 (test system) 2.50 125.00FI 2531-1010 M 10 x 10 (test system) 2.30 230.00FI 2531-2005 M 20 x 05 (test system) 2.40 240.00FK 2531-1003 10 x 03 (single slides) 2.00 60.00FK 2531-1005 10 x 05 (single slides) 1.90 95.00FK 2531-1010 10 x 10 (single slides) 1.70 170.00FK 2531-2005 20 x 05 (single slides) 1.80 180.00

FI 2531-1003-1 G “BIOCHIP Mosaic” IgG 2 BIOCHIPs per field: 10 x 03 (test system) 4.20 126.00FI 2531-1005-1 G HSV-1/HSV-2 infected EU 38 10 x 05 (test system) 4.00 200.00FI 2531-1010-1 G cells 10 x 10 (test system) 3.60 360.00FI 2531-2005-1 G 20 x 05 (test system) 3.80 380.00FI 2531-1003-1 M IgM 10 x 03 (test system) 4.20 126.00FI 2531-1005-1 M 10 x 05 (test system) 4.00 200.00FI 2531-1010-1 M 10 x 10 (test system) 3.60 360.00FI 2531-2005-1 M 20 x 05 (test system) 3.80 380.00FK 2531-1003-1 10 x 03 (single slides) 3.20 96.00FK 2531-1005-1 10 x 05 (single slides) 3.10 155.00FK 2531-1010-1 10 x 10 (single slides) 2.70 270.00FK 2531-2005-1 20 x 05 (single slides) 2.90 290.00

FI 2532-1003 G Herpes simplex virus 2 IgG infected EU 38 10 x 03 (test system) 2.60 78.00FI 2532-1005 G (HSV-2) cells 10 x 05 (test system) 2.50 125.00FI 2532-1010 G 10 x 10 (test system) 2.30 230.00FI 2532-2005 G 20 x 05 (test system) 2.40 240.00FI 2532-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2532-1005 M 10 x 05 (test system) 2.50 125.00FI 2532-1010 M 10 x 10 (test system) 2.30 230.00FI 2532-2005 M 20 x 05 (test system) 2.40 240.00FK 2532-1003 10 x 03 (single slides) 2.00 60.00FK 2532-1005 10 x 05 (single slides) 1.90 95.00FK 2532-1010 10 x 10 (single slides) 1.70 170.00FK 2532-2005 20 x 05 (single slides) 1.80 180.00

FI 2536-1003 G Human herpes virus 6 IgG infected EU 38 10 x 03 (test system) 2.60 78.00FI 2536-1005 G (HHV-6) cells 10 x 05 (test system) 2.50 125.00FI 2536-1010 G 10 x 10 (test system) 2.30 230.00FI 2536-2005 G 20 x 05 (test system) 2.40 240.00FI 2536-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2536-1005 M 10 x 05 (test system) 2.50 125.00FI 2536-1010 M 10 x 10 (test system) 2.30 230.00FI 2536-2005 M 20 x 05 (test system) 2.40 240.00FK 2536-1003 10 x 03 (single slides) 2.00 60.00FK 2536-1005 10 x 05 (single slides) 1.90 95.00FK 2536-1010 10 x 10 (single slides) 1.70 170.00FK 2536-2005 20 x 05 (single slides) 1.80 180.00

FI 2570-1003 A Cytomegalovirus IgA infected EU 168 10 x 03 (test system) 2.60 78.00FI 2570-1005 A (CMV) cells 10 x 05 (test system) 2.50 125.00FI 2570-1010 A 10 x 10 (test system) 2.30 230.00FI 2570-2005 A 20 x 05 (test system) 2.40 240.00FI 2570-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2570-1005 G 10 x 05 (test system) 2.50 125.00FI 2570-1010 G 10 x 10 (test system) 2.30 230.00FI 2570-2005 G 20 x 05 (test system) 2.40 240.00FI 2570-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2570-1005 M 10 x 05 (test system) 2.50 125.00FI 2570-1010 M 10 x 10 (test system) 2.30 230.00FI 2570-2005 M 20 x 05 (test system) 2.40 240.00FK 2570-1003 10 x 03 (single slides) 2.00 60.00FK 2570-1005 10 x 05 (single slides) 1.90 95.00FK 2570-1010 10 x 10 (single slides) 1.70 170.00FK 2570-2005 20 x 05 (single slides) 1.80 180.00

FI 2590-1005 G Rubella virus IgG infected EU 13 10 x 05 (test system) 2.50 125.00FI 2590-1010 G cells 10 x 10 (test system) 2.30 230.00FI 2590-2005 G 20 x 05 (test system) 2.40 240.00FI 2590-1005 X (avidity test) 10 x 05 (test system) 2.50 125.00FI 2590-1010 X 10 x 10 (test system) 2.30 230.00FI 2590-2005 X 20 x 05 (test system) 2.40 240.00FK 2590-1005 10 x 05 (single slides) 1.90 95.00FK 2590-1010 10 x 10 (single slides) 1.70 170.00FK 2590-2005 20 x 05 (single slides) 1.80 180.00

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2601-1010 A SARS coronavirus IgA infected and non- EU 14 10 x 10 (test system) 2.60 260.00FI 2601-2010 A infected cells 20 x 10 (test system) 2.50 500.00FI 2601-1010 G IgG (2 BIOCHIPs per field) 10 x 10 (test system) 2.60 260.00FI 2601-2010 G 20 x 10 (test system) 2.50 500.00FI 2601-1010 M IgM 10 x 10 (test system) 2.60 260.00FI 2601-2010 M 20 x 10 (test system) 2.50 500.00FK 2601-1010 10 x 10 (single slides) 2.00 200.00FK 2601-2010 20 x 10 (single slides) 1.90 380.00

FI 2610-1003 G Measles virus IgG infected EU 38 10 x 03 (test system) 2.60 78.00FI 2610-1005 G cells 10 x 05 (test system) 2.50 125.00FI 2610-1010 G 10 x 10 (test system) 2.30 230.00FI 2610-2005 G 20 x 05 (test system) 2.40 240.00FI 2610-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2610-1005 M 10 x 05 (test system) 2.50 125.00FI 2610-1010 M 10 x 10 (test system) 2.30 230.00FI 2610-2005 M 20 x 05 (test system) 2.40 240.00FK 2610-1003 10 x 03 (single slides) 2.00 60.00FK 2610-1005 10 x 05 (single slides) 1.90 95.00FK 2610-1010 10 x 10 (single slides) 1.70 170.00FK 2610-2005 20 x 05 (single slides) 1.80 180.00

FI 2630-1003 G Mumps virus IgG infected EU 13 10 x 03 (test system) 2.60 78.00FI 2630-1005 G cells 10 x 05 (test system) 2.50 125.00FI 2630-1010 G 10 x 10 (test system) 2.30 230.00FI 2630-2005 G 20 x 05 (test system) 2.40 240.00FI 2630-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2630-1005 M 10 x 05 (test system) 2.50 125.00FI 2630-1010 M 10 x 10 (test system) 2.30 230.00FI 2630-2005 M 20 x 05 (test system) 2.40 240.00FK 2630-1003 10 x 03 (single slides) 2.00 60.00FK 2630-1005 10 x 05 (single slides) 1.90 95.00FK 2630-1010 10 x 10 (single slides) 1.70 170.00FK 2630-2005 20 x 05 (single slides) 1.80 180.00

FI 2650-1003 A Varicella zoster virus IgA infected EU 168 10 x 03 (test system) 2.60 78.00FI 2650-1005 A (VZV) cells 10 x 05 (test system) 2.50 125.00FI 2650-1010 A 10 x 10 (test system) 2.30 230.00FI 2650-2005 A 20 x 05 (test system) 2.40 240.00FI 2650-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2650-1005 G 10 x 05 (test system) 2.50 125.00FI 2650-1010 G 10 x 10 (test system) 2.30 230.00FI 2650-2005 G 20 x 05 (test system) 2.40 240.00FI 2650-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2650-1005 M 10 x 05 (test system) 2.50 125.00FI 2650-1010 M 10 x 10 (test system) 2.30 230.00FI 2650-2005 M 20 x 05 (test system) 2.40 240.00FK 2650-1003 10 x 03 (single slides) 2.00 60.00FK 2650-1005 10 x 05 (single slides) 1.90 95.00FK 2650-1010 10 x 10 (single slides) 1.70 170.00FK 2650-2005 20 x 05 (single slides) 1.80 180.00

FI 2661-1005 A TBE virus IgA infected and non- EU 14 10 x 05 (test system) 2.90 145.00FI 2661-1010 A infected cells 10 x 10 (test system) 2.60 260.00FI 2661-2005 A (2 BIOCHIPs per field) 20 x 05 (test system) 2.70 270.00FI 2661-1005 G IgG 10 x 05 (test system) 2.90 145.00FI 2661-1010 G 10 x 10 (test system) 2.60 260.00FI 2661-2005 G 20 x 05 (test system) 2.70 270.00FI 2661-1005 M IgM 10 x 05 (test system) 2.90 145.00FI 2661-1010 M 10 x 10 (test system) 2.60 260.00FI 2661-2005 M 20 x 05 (test system) 2.70 270.00FK 2661-1005 10 x 05 (single slides) 2.20 110.00FK 2661-1010 10 x 10 (single slides) 2.00 200.00FK 2661-2005 20 x 05 (single slides) 2.10 210.00

FI 2661-1005-1 G “Flavivirus Mosaic 1” IgG 4 BIOCHIPs per field: 10 x 05 (test system) 8.20 410.00FI 2661-1010-1 G TBE virus infected cells EU 14 10 x 10 (test system) 7.40 740.00FI 2661-2010-1 G West-Nile virus infected cells EU 14 20 x 10 (test system) 7.00 1,400.00FI 2661-1005-1 M Japanese encephalitis virus IgM infected cells EU 14 10 x 05 (test system) 8.20 410.00FI 2661-1010-1 M Yellow fever virus infected cells EU 14 10 x 10 (test system) 7.40 740.00FI 2661-2010-1 M 20 x 10 (test system) 7.00 1,400.00FK 2661-1005-1 10 x 05 (single slides) 6.20 310.00FK 2661-1010-1 10 x 10 (single slides) 5.60 560.00FK 2661-2010-1 20 x 10 (single slides) 5.30 1,060.00

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rIn

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2661-1005-2 G “Flavivirus Profile 2” IgG 10 x 05 (test system) 14.80 740.00FI 2661-2005-2 G upper row : 20 x 05 (test system) 14.10 1,410.00FK 2661-1005-2 TBE virus infected cells EU 14 10 x 05 (single slides) 11.10 555.00FK 2661-2005-2 West Nile virus infected cells EU 14 20 x 05 (single slides) 10.60 1,060.00

Japanese encephalitis virus infected cells EU 14Yellow fever virus infected cells EU 14

bottom row :Dengue virus infected cells EU 14types 1 to 4

FI 2662-1005 G West Nile virus IgG infected and non- EU 14 10 x 05 (test system) 2.90 145.00FI 2662-1010 G infected cells 10 x 10 (test system) 2.60 260.00FI 2662-2005 G (2 BIOCHIPs per field) 20 x 05 (test system) 2.70 270.00FI 2662-1005 M IgM 10 x 05 (test system) 2.90 145.00FI 2662-1010 M 10 x 10 (test system) 2.60 260.00FI 2662-2005 M 20 x 05 (test system) 2.70 270.00FI 2662-1005 X (avidity test) 10 x 05 (test system) 2.90 145.00FI 2662-1010 X 10 x 10 (test system) 2.60 260.00FI 2662-2005 X 20 x 05 (test system) 2.70 270.00FK 2662-1005 10 x 05 (single slides) 2.20 110.00FK 2662-1010 10 x 10 (single slides) 2.00 200.00FK 2662-2005 20 x 05 (single slides) 2.10 210.00

FI 2663-1005 G * Japanese encephalitis virus IgG infected and non- EU 14 10 x 05 (test system) 2.90 145.00FI 2663-1010 G * infected cells 10 x 10 (test system) 2.60 260.00FI 2663-2005 G * (2 BIOCHIPs per field) 20 x 05 (test system) 2.70 270.00FI 2663-1005 M * IgM 10 x 05 (test system) 2.90 145.00FI 2663-1010 M * 10 x 10 (test system) 2.60 260.00FI 2663-2005 M * 20 x 05 (test system) 2.70 270.00FK 2663-1005 * 10 x 05 (single slides) 2.20 110.00FK 2663-1010 * 10 x 10 (single slides) 2.00 200.00FK 2663-2005 * 20 x 05 (single slides) 2.10 210.00

FI 2665-1005 G Yellow fever virus IgG infected and non- EU 14 10 x 05 (test system) 2.90 145.00FI 2665-1010 G infected cells 10 x 10 (test system) 2.60 260.00FI 2665-2005 G (2 BIOCHIPs per field) 20 x 05 (test system) 2.70 270.00FI 2665-1005 M IgM 10 x 05 (test system) 2.90 145.00FI 2665-1010 M 10 x 10 (test system) 2.60 260.00FI 2665-2005 M 20 x 05 (test system) 2.70 270.00FK 2665-1005 10 x 05 (single slides) 2.20 110.00FK 2665-1010 10 x 10 (single slides) 2.00 200.00FK 2665-2005 20 x 05 (single slides) 2.10 210.00

FI 266a-1003-1 G “Mosaic Dengue virus” IgG 4 BIOCHIPs per field: 10 x 03 (test system) 8.50 255.00FI 266a-1005-1 G types 1 to 4 infected EU 14 10 x 05 (test system) 8.20 410.00FI 266a-1010-1 G cells 10 x 10 (test system) 7.40 740.00FI 266a-2005-1 G 20 x 05 (test system) 7.80 780.00FI 266a-1003-1 M IgM 10 x 03 (test system) 8.50 255.00FI 266a-1005-1 M 10 x 05 (test system) 8.20 410.00FI 266a-1010-1 M 10 x 10 (test system) 7.40 740.00FI 266a-2005-1 M 20 x 05 (test system) 7.80 780.00FK 266a-1003-1 10 x 03 (single slides) 6.40 192.00FK 266a-1005-1 10 x 05 (single slides) 6.20 310.00FK 266a-1010-1 10 x 10 (single slides) 5.60 560.00FK 266a-2005-1 20 x 05 (single slides) 5.90 590.00

FI 2670-1003 A Respiratory syncytial virus IgA infected EU 38 10 x 03 (test system) 2.60 78.00FI 2670-1005 A (RSV) cells 10 x 05 (test system) 2.50 125.00FI 2670-1010 A 10 x 10 (test system) 2.20 220.00FI 2670-2005 A 20 x 05 (test system) 2.40 240.00FI 2670-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2670-1005 G 10 x 05 (test system) 2.50 125.00FI 2670-1010 G 10 x 10 (test system) 2.20 220.00FI 2670-2005 G 20 x 05 (test system) 2.40 240.00FI 2670-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2670-1005 M 10 x 05 (test system) 2.50 125.00FI 2670-1010 M 10 x 10 (test system) 2.20 220.00FI 2670-2005 M 20 x 05 (test system) 2.40 240.00FK 2670-1003 10 x 03 (single slides) 2.00 60.00FK 2670-1005 10 x 05 (single slides) 1.90 95.00FK 2670-1010 10 x 10 (single slides) 1.70 170.00FK 2670-2005 20 x 05 (single slides) 1.80 180.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2680-1003 A Adenovirus IgA infected EU 38 10 x 03 (test system) 2.60 78.00FI 2680-1005 A type 3 cells 10 x 05 (test system) 2.50 125.00FI 2680-1010 A 10 x 10 (test system) 2.30 230.00FI 2680-2005 A 20 x 05 (test system) 2.40 240.00FI 2680-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2680-1005 G 10 x 05 (test system) 2.50 125.00FI 2680-1010 G 10 x 10 (test system) 2.30 230.00FI 2680-2005 G 20 x 05 (test system) 2.40 240.00FI 2680-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2680-1005 M 10 x 05 (test system) 2.50 125.00FI 2680-1010 M 10 x 10 (test system) 2.30 230.00FI 2680-2005 M 20 x 05 (test system) 2.40 240.00FK 2680-1003 10 x 03 (single slides) 2.00 60.00FK 2680-1005 10 x 05 (single slides) 1.90 95.00FK 2680-1010 10 x 10 (single slides) 1.70 170.00FK 2680-2005 20 x 05 (single slides) 1.80 180.00

FI 2691-1003 A Influenza virus type A IgA infected EU 50 10 x 03 (test system) 2.60 78.00FI 2691-1005 A cells 10 x 05 (test system) 2.50 125.00FI 2691-1010 A 10 x 10 (test system) 2.30 230.00FI 2691-2005 A 20 x 05 (test system) 2.40 240.00FI 2691-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2691-1005 G 10 x 05 (test system) 2.50 125.00FI 2691-1010 G 10 x 10 (test system) 2.30 230.00FI 2691-2005 G 20 x 05 (test system) 2.40 240.00FI 2691-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2691-1005 M 10 x 05 (test system) 2.50 125.00FI 2691-1010 M 10 x 10 (test system) 2.30 230.00FI 2691-2005 M 20 x 05 (test system) 2.40 240.00FK 2691-1003 10 x 03 (single slides) 2.00 60.00FK 2691-1005 10 x 05 (single slides) 1.90 95.00FK 2691-1010 10 x 10 (single slides) 1.70 170.00FK 2691-2005 20 x 05 (single slides) 1.80 180.00

FI 2691-1003-1 A Influenza virus type A IgA infected EU 50 10 x 03 (test system) 4.20 126.00FI 2691-1005-1 A Influenza virus type B cells EU 50 10 x 05 (test system) 4.00 200.00FI 2691-1010-1 A (2 BIOCHIPs per field) 10 x 10 (test system) 3.60 360.00FI 2691-2005-1 A 20 x 05 (test system) 3.80 380.00FI 2691-1003-1 G IgG 10 x 03 (test system) 4.20 126.00FI 2691-1005-1 G 10 x 05 (test system) 4.00 200.00FI 2691-1010-1 G 10 x 10 (test system) 3.60 360.00FI 2691-2005-1 G 20 x 05 (test system) 3.80 380.00FI 2691-1003-1 M IgM 10 x 03 (test system) 4.20 126.00FI 2691-1005-1 M 10 x 05 (test system) 4.00 200.00FI 2691-1010-1 M 10 x 10 (test system) 3.60 360.00FI 2691-2005-1 M 20 x 05 (test system) 3.80 380.00FK 2691-1003-1 10 x 03 (single slides) 3.20 96.00FK 2691-1005-1 10 x 05 (single slides) 3.10 155.00FK 2691-1010-1 10 x 10 (single slides) 2.70 270.00FK 2691-2005-1 20 x 05 (single slides) 2.90 290.00

FI 2692-1003 A Influenza virus type B IgA infected EU 13 10 x 03 (test system) 2.60 78.00FI 2692-1005 A cells 10 x 05 (test system) 2.50 125.00FI 2692-1010 A 10 x 10 (test system) 2.30 230.00FI 2692-2005 A 20 x 05 (test system) 2.40 240.00FI 2692-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2692-1005 G 10 x 05 (test system) 2.50 125.00FI 2692-1010 G 10 x 10 (test system) 2.30 230.00FI 2692-2005 G 20 x 05 (test system) 2.40 240.00FI 2692-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2692-1005 M 10 x 05 (test system) 2.50 125.00FI 2692-1010 M 10 x 10 (test system) 2.30 230.00FI 2692-2005 M 20 x 05 (test system) 2.40 240.00FK 2692-1003 10 x 03 (single slides) 2.00 60.00FK 2692-1005 10 x 05 (single slides) 1.90 95.00FK 2692-1010 10 x 10 (single slides) 1.70 170.00FK 2692-2005 20 x 05 (single slides) 1.80 180.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2721-1003-1 A “Mosaic Parainfluenza virus” IgA infected EU 18/9 10 x 03 (test system) 7.00 210.00FI 2721-1005-1 A types 1 - 4 cells 10 x 05 (test system) 6.80 340.00FI 2721-1010-1 A (4 BIOCHIPs per field) 10 x 10 (test system) 6.10 610.00FI 2721-2005-1 A 20 x 05 (test system) 6.40 640.00FI 2721-1003-1 G IgG 10 x 03 (test system) 7.00 210.00FI 2721-1005-1 G 10 x 05 (test system) 6.80 340.00FI 2721-1010-1 G 10 x 10 (test system) 6.10 610.00FI 2721-2005-1 G 20 x 05 (test system) 6.40 640.00FI 2721-1003-1 M IgM 10 x 03 (test system) 7.00 210.00FI 2721-1005-1 M 10 x 05 (test system) 6.80 340.00FI 2721-1010-1 M 10 x 10 (test system) 6.10 610.00FI 2721-2005-1 M 20 x 05 (test system) 6.40 640.00FK 2721-1003-1 10 x 03 (single slides) 5.30 159.00FK 2721-1005-1 10 x 05 (single slides) 5.10 255.00FK 2721-1010-1 10 x 10 (single slides) 4.60 460.00FK 2721-2005-1 20 x 05 (single slides) 4.80 480.00

FI 2730-1003-1 A “Mosaic Coxsackie virus” IgA 9 BIOCHIPs per field: 10 x 03 (test system) 14.40 432.00FI 2730-1005-1 A Coxsackie virus infected EU 38 10 x 05 (test system) 13.80 690.00FI 2730-2005-1 A types A7, A9, A16, A24, cells 20 x 05 (test system) 13.20 1,320.00FI 2730-1003-1 G B1, B2, B3, B4, B5 IgG 10 x 03 (test system) 14.40 432.00FI 2730-1005-1 G 10 x 05 (test system) 13.80 690.00FI 2730-2005-1 G 20 x 05 (test system) 13.20 1,320.00FI 2730-1003-1 M IgM 10 x 03 (test system) 14.40 432.00FI 2730-1005-1 M 10 x 05 (test system) 13.80 690.00FI 2730-2005-1 M 20 x 05 (test system) 13.20 1,320.00FK 2730-1003-1 10 x 03 (single slides) 10.80 324.00FK 2730-1005-1 10 x 05 (single slides) 10.40 520.00FK 2730-2005-1 20 x 05 (single slides) 9.90 990.00

FI 2730-1003-2 A “Mosaic Coxsackie virus A types” IgA 4 BIOCHIPs per field: 10 x 03 (test system) 7.00 210.00FI 2730-1005-2 A Coxsackie virus infected EU 38 10 x 05 (test system) 6.80 340.00FI 2730-2005-2 A types A7, A9, A16, A24 cells 20 x 05 (test system) 6.40 640.00FI 2730-1003-2 G IgG 10 x 03 (test system) 7.00 210.00FI 2730-1005-2 G 10 x 05 (test system) 6.80 340.00FI 2730-2005-2 G 20 x 05 (test system) 6.40 640.00FI 2730-1003-2 M IgM 10 x 03 (test system) 7.00 210.00FI 2730-1005-2 M 10 x 05 (test system) 6.80 340.00FI 2730-2005-2 M 20 x 05 (test system) 6.40 640.00FK 2730-1003-2 10 x 03 (single slides) 5.30 159.00FK 2730-1005-2 10 x 05 (single slides) 5.10 255.00FK 2730-2005-2 20 x 05 (single slides) 4.80 480.00

FI 2730-1003-3 A “Mosaic Coxsackie virus B types” IgA 6 BIOCHIPs per field: 10 x 03 (test system) 9.90 297.00FI 2730-1005-3 A Coxsackie virus infected EU 38 10 x 05 (test system) 9.60 480.00FI 2730-2005-3 A types B1, B2, B3, B4, B5, B6 cells 20 x 05 (test system) 9.10 910.00FI 2730-1003-3 G IgG 10 x 03 (test system) 9.90 297.00FI 2730-1005-3 G 10 x 05 (test system) 9.60 480.00FI 2730-2005-3 G 20 x 05 (test system) 9.10 910.00FI 2730-1003-3 M IgM 10 x 03 (test system) 9.90 297.00FI 2730-1005-3 M 10 x 05 (test system) 9.60 480.00FI 2730-2005-3 M 20 x 05 (test system) 9.10 910.00FK 2730-1003-3 10 x 03 (single slides) 7.50 225.00FK 2730-1005-3 10 x 05 (single slides) 7.20 360.00FK 2730-2005-3 20 x 05 (single slides) 6.80 680.00

FI 2730-1003-4 A Coxsackie virus type A7 IgA infected EU 38 10 x 03 (test system) 4.20 126.00FI 2730-1005-4 A Coxsackie virus type B1 cells EU 38 10 x 05 (test system) 4.00 200.00FI 2730-1010-4 A (2 BIOCHIPs per field) 10 x 10 (test system) 3.60 360.00FI 2730-2005-4 A 20 x 05 (test system) 3.80 380.00FI 2730-1003-4 G IgG 10 x 03 (test system) 4.20 126.00FI 2730-1005-4 G 10 x 05 (test system) 4.00 200.00FI 2730-1010-4 G 10 x 10 (test system) 3.60 360.00FI 2730-2005-4 G 20 x 05 (test system) 3.80 380.00FI 2730-1003-4 M IgM 10 x 03 (test system) 4.20 126.00FI 2730-1005-4 M 10 x 05 (test system) 4.00 200.00FI 2730-1010-4 M 10 x 10 (test system) 3.60 360.00FI 2730-2005-4 M 20 x 05 (test system) 3.80 380.00FK 2730-1003-4 10 x 03 (single slides) 3.20 96.00FK 2730-1005-4 10 x 05 (single slides) 3.10 155.00FK 2730-1010-4 10 x 10 (single slides) 2.70 270.00FK 2730-2005-4 20 x 05 (single slides) 2.90 290.00

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EUROIMMUNM e d i z i n i s c h eL a b o r d i a g n o s t i k aA G

Imm

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sce

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sts

for

Infe

ctio

us S

ero

log

y

Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2730-1005-5 G “Enterovirus Mosaic 1” IgG 3 BIOCHIPs per field: 10 x 05 (test system) 5.30 265.00FI 2730-1010-5 G Coxsackie virus type A7 infected cells EU 38 10 x 10 (test system) 4.70 470.00FI 2730-1005-5 M Coxsackie virus type B1 IgM infected cells EU 38 10 x 05 (test system) 5.30 265.00FI 2730-1010-5 M Echo virus type 7 infected cells EU 38 10 x 10 (test system) 4.70 470.00FK 2730-1005-5 10 x 05 (single slides) 4.00 200.00FK 2730-1010-5 10 x 10 (single slides) 3.60 360.00

FI 2731-1005 A Coxsackie virus type B1 IgA infected EU 38 10 x 05 (test system) 2.50 125.00FI 2731-1010 A cells 10 x 10 (test system) 2.30 230.00FI 2731-2005 A 20 x 05 (test system) 2.40 240.00FI 2731-1005 G IgG 10 x 05 (test system) 2.50 125.00FI 2731-1010 G 10 x 10 (test system) 2.30 230.00FI 2731-2005 G 20 x 05 (test system) 2.40 240.00FI 2731-1005 M IgM 10 x 05 (test system) 2.50 125.00FI 2731-1010 M 10 x 10 (test system) 2.30 230.00FI 2731-2005 M 20 x 05 (test system) 2.40 240.00FK 2731-1005 10 x 05 (single slides) 1.90 95.00FK 2731-1010 10 x 10 (single slides) 1.70 170.00FK 2731-2005 20 x 05 (single slides) 1.80 180.00

FI 2737-1005 A Coxsackie virus type A7 IgA infected EU 38 10 x 05 (test system) 2.50 125.00FI 2737-1010 A cells 10 x 10 (test system) 2.30 230.00FI 2737-2005 A 20 x 05 (test system) 2.40 240.00FI 2737-1005 G IgG 10 x 05 (test system) 2.50 125.00FI 2737-1010 G 10 x 10 (test system) 2.30 230.00FI 2737-2005 G 20 x 05 (test system) 2.40 240.00FI 2737-1005 M IgM 10 x 05 (test system) 2.50 125.00FI 2737-1010 M 10 x 10 (test system) 2.30 230.00FI 2737-2005 M 20 x 05 (test system) 2.40 240.00FK 2737-1005 10 x 05 (single slides) 1.90 95.00FK 2737-1010 10 x 10 (single slides) 1.70 170.00FK 2737-2005 20 x 05 (single slides) 1.80 180.00

FI 275a-1005 A Echo virus IgA infected EU 38 10 x 05 (test system) 2.50 125.00FI 275a-1010 A type 7 cells 10 x 10 (test system) 2.30 230.00FI 275a-2005 A 20 x 05 (test system) 2.40 240.00FI 275a-1005 G IgG 10 x 05 (test system) 2.50 125.00FI 275a-1010 G 10 x 10 (test system) 2.30 230.00FI 275a-2005 G 20 x 05 (test system) 2.40 240.00FI 275a-1005 M IgM 10 x 05 (test system) 2.50 125.00FI 275a-1010 M 10 x 10 (test system) 2.30 230.00FI 275a-2005 M 20 x 05 (test system) 2.40 240.00FK 275a-1005 10 x 05 (single slides) 1.90 95.00FK 275a-1010 10 x 10 (single slides) 1.70 170.00FK 275a-2005 20 x 05 (single slides) 1.80 180.00

FI 277a-1005-1 G * “Sandfly fever virus Mosaic 1” IgG 4 BIOCHIPs per field: 10 x 05 (test system) 8.20 410.00FI 277a-1010-1 G * Sandfly fever virus infected cells EU 14 10 x 10 (test system) 7.40 740.00FI 277a-2005-1 G * (types Sicilian, Naples, Toscana, Cyprus) 20 x 05 (test system) 7.80 780.00FI 277a-1005-1 M * IgM 10 x 05 (test system) 8.20 410.00FI 277a-1010-1 M * 10 x 10 (test system) 7.40 740.00FI 277a-2010-1 M * 20 x 10 (test system) 7.00 1,400.00FK 277a-1005-1 * 10 x 05 (single slides) 6.20 310.00FK 277a-1010-1 * 10 x 10 (single slides) 5.60 560.00FK 277a-2005-1 * 20 x 05 (single slides) 5.90 590.00

FI 278h-1005-1 G “Hanta virus Mosaic 1” IgG 6 BIOCHIPs per field: 10 x 05 (test system) 11.70 585.00FI 278h-1010-1 G types Hantaan, Sin Nombre, Puumala, infected EU 14 10 x 10 (test system) 10.60 1,060.00FI 278h-2010-1 G Dobrava, Seoul, Saaremaa cells 20 x 10 (test system) 10.00 2,000.00FI 278h-1005-1 M IgM 10 x 05 (test system) 11.70 585.00FI 278h-1010-1 M 10 x 10 (test system) 10.60 1,060.00FI 278h-2010-1 M 20 x 10 (test system) 10.00 2,000.00FK 278h-1005-1 10 x 05 (single slides) 8.80 440.00FK 278h-1010-1 10 x 10 (single slides) 8.00 800.00FK 278h-2010-1 20 x 10 (single slides) 7.50 1,500.00

FI 278h-1005-2 G “Hanta virus Mosaic Eurasia1” IgG 6 BIOCHIPs per field: 10 x 05 (test system) 10.20 510.00FI 278h-1010-2 G types Hantaan, Puumala, infected and non- EU 14 10 x 10 (test system) 9.20 920.00FI 278h-2010-2 G Dobrava, Seoul, Saaremaa infected cells 20 x 10 (test system) 8.70 1,740.00FI 278h-1005-2 M IgM 10 x 05 (test system) 10.20 510.00FI 278h-1010-2 M 10 x 10 (test system) 9.20 920.00FI 278h-2010-2 M 20 x 10 (test system) 8.70 1,740.00FK 278h-1005-2 10 x 05 (single slides) 7.70 385.00FK 278h-1010-2 10 x 10 (single slides) 6.90 690.00FK 278h-2010-2 20 x 10 (single slides) 6.60 1,320.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2791-1003 A Epstein-Barr IgA expressing P3HR1 10 x 03 (test system) 2.60 78.00FI 2791-1005 A virus capsid antigen cells 10 x 05 (test system) 2.50 125.00FI 2791-1010 A (EBV-CA) 10 x 10 (test system) 2.30 230.00FI 2791-2005 A 20 x 05 (test system) 2.40 240.00FK 2791-1003 A 10 x 03 (single slides) 2.00 60.00FK 2791-1005 A 10 x 05 (single slides) 1.90 95.00FK 2791-1010 A 10 x 10 (single slides) 1.70 170.00FK 2791-2005 A 20 x 05 (single slides) 1.80 180.00FI 2791-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2791-1005 G 10 x 05 (test system) 2.50 125.00FI 2791-1010 G 10 x 10 (test system) 2.30 230.00FI 2791-2005 G 20 x 05 (test system) 2.40 240.00FK 2791-1003 G 10 x 03 (single slides) 2.00 60.00FK 2791-1005 G 10 x 05 (single slides) 1.90 95.00FK 2791-1010 G 10 x 10 (single slides) 1.70 170.00FK 2791-2005 G 20 x 05 (single slides) 1.80 180.00FI 2791-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2791-1005 M 10 x 05 (test system) 2.50 125.00FI 2791-1010 M 10 x 10 (test system) 2.30 230.00FI 2791-2005 M 20 x 05 (test system) 2.40 240.00FK 2791-1003 M 10 x 03 (single slides) 2.00 60.00FK 2791-1005 M 10 x 05 (single slides) 1.90 95.00FK 2791-1010 M 10 x 10 (single slides) 1.70 170.00FK 2791-2005 M 20 x 05 (single slides) 1.80 180.00FI 2791-1003 X (avidity test) 10 x 03 (test system) 2.60 78.00FI 2791-1005 X 10 x 05 (test system) 2.50 125.00FI 2791-1010 X 10 x 10 (test system) 2.30 230.00FI 2791-2005 X 20 x 05 (test system) 2.40 240.00

FI 2791-1003-2 A EBV capsid antigen (EBV-CA) IgA expressing P3HR1 10 x 03 (test system) 4.20 126.00FI 2791-1005-2 A EBV early antigen (EBV-EA) cells EU 33 10 x 05 (test system) 4.00 200.00FI 2791-1010-2 A (2 BIOCHIPs per field) 10 x 10 (test system) 3.60 360.00FI 2791-2005-2 A 20 x 05 (test system) 3.80 380.00FI 2791-1003-2 G IgG 10 x 03 (test system) 4.20 126.00FI 2791-1005-2 G 10 x 05 (test system) 4.00 200.00FI 2791-1010-2 G 10 x 10 (test system) 3.60 360.00FI 2791-2005-2 G 20 x 05 (test system) 3.80 380.00FI 2791-1003-2 X (avidity test) 10 x 03 (test system) 4.20 126.00FI 2791-1005-2 X 10 x 05 (test system) 4.00 200.00FI 2791-1010-2 X 10 x 10 (test system) 3.60 360.00FI 2791-2005-2 X 20 x 05 (test system) 3.80 380.00FK 2791-1003-2 10 x 03 (single slides) 3.20 96.00FK 2791-1005-2 10 x 05 (single slides) 3.10 155.00FK 2791-1010-2 10 x 10 (single slides) 2.70 270.00FK 2791-2005-2 20 x 05 (single slides) 2.90 290.00

FI 2793-1003 C Epstein-Barr virus expressing Raji 10 x 03 (test system) 2.60 78.00FI 2793-1005 C nuclear antigen (EBNA, cells 10 x 05 (test system) 2.50 125.00FI 2793-1010 C complement-fixing antibodies) 10 x 10 (test system) 2.30 230.00FI 2793-2005 C 20 x 05 (test system) 2.40 240.00FK 2793-1003 10 x 03 (single slides) 2.00 60.00FK 2793-1005 10 x 05 (single slides) 1.90 95.00FK 2793-1010 10 x 10 (single slides) 1.70 170.00FK 2793-2005 20 x 05 (single slides) 1.80 180.00

FI 2795-1003 A Epstein-Barr IgA expressing EU 33 10 x 03 (test system) 2.60 78.00FI 2795-1005 A virus early antigen cells 10 x 05 (test system) 2.50 125.00FI 2795-1010 A (EBV-EA) 10 x 10 (test system) 2.30 230.00FI 2795-2005 A 20 x 05 (test system) 2.40 240.00FI 2795-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2795-1005 G 10 x 05 (test system) 2.50 125.00FI 2795-1010 G 10 x 10 (test system) 2.30 230.00FI 2795-2005 G 20 x 05 (test system) 2.40 240.00FI 2795-1003 X (avidity test) 10 x 03 (test system) 2.60 78.00FI 2795-1005 X 10 x 05 (test system) 2.50 125.00FI 2795-1010 X 10 x 10 (test system) 2.30 230.00FI 2795-2005 X 20 x 05 (test system) 2.40 240.00FK 2795-1003 10 x 03 (single slides) 2.00 60.00FK 2795-1005 10 x 05 (single slides) 1.90 95.00FK 2795-1010 10 x 10 (single slides) 1.70 170.00FK 2795-2005 20 x 05 (single slides) 1.80 180.00

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

FI 2799-1001-1 “BIOCHIP Sequence EBV” 10 x 01 (test system) 6.40 64.00FI 2799-1002-1 fields A & B: EBV-CA (IgG) expressing cells P3HR1 10 x 02 (test system) 5.80 116.00FI 2799-1010-1 field C: EBV-CA (IgM) expressing cells P3HR1 10 x 10 (test system) 4.50 450.00FI 2799-2001-1 field D: EBV-EA expressing cells EU 33 20 x 01 (test system) 6.10 122.00FI 2799-2002-1 field E: EBNA expressing cells Raji 20 x 02 (test system) 5.50 220.00FK 2799-1001-1 format 1001: per slide one patient 10 x 01 (single slides) 4.80 48.00FK 2799-1002-1 format 1002: per slide two patients 10 x 02 (single slides) 4.40 88.00FK 2799-1010-1 format 1010: per slide ten patients 10 x 10 (single slides) 3.80 380.00FK 2799-2001-1 20 x 01 (single slides) 4.60 92.00FK 2799-2002-1 20 x 02 (single slides) 4.10 164.00

FI 2799-1001-1 X “BIOCHIP Sequence EBV (avidity test)” 10 x 01 (test system) 6.40 64.00FI 2799-1002-1 X fields A & B: EBV-CA (IgG) expressing cells P3HR1 10 x 02 (test system) 5.80 116.00FI 2799-1010-1 X field C: EBV-CA (IgM) expressing cells P3HR1 10 x 10 (test system) 4.50 450.00FI 2799-2001-1 X field D: EBV-EA expressing cells EU 33 20 x 01 (test system) 6.10 122.00FI 2799-2002-1 X field E: EBNA expressing cells Raji 20 x 02 (test system) 5.50 220.00

format 1001: per slide one patientformat 1002: per slide two patientsformat 1010: per slide ten patients

BIOCHIP Mosaics for infectious serology. One slide for one patient (e.g. FI 2821-1001-1 G) or two patients (e.g. FI 2821-1002-1 G), respectively, for thecombination of substrates see pages 54/55.

FI 2821-1001-1 G “Respiratory Tract Profile 1” IgG 10 x 01 (test system) 28.80 288.00FI 2821-1002-1 G (consisting of 20 different substrates) 10 x 02 (test system) 25.90 518.00FI 2821-2001-1 G 20 x 01 (test system) 27.30 546.00FI 2821-2002-1 G 20 x 02 (test system) 24.60 984.00FI 2821-1001-1 M IgM 10 x 01 (test system) 28.80 288.00FI 2821-1002-1 M 10 x 02 (test system) 25.90 518.00FI 2821-2001-1 M 20 x 01 (test system) 27.30 546.00FI 2821-2002-1 M 20 x 02 (test system) 24.60 984.00FK 2821-1001-1 10 x 01 (single slides) 21.60 216.00FK 2821-1002-1 10 x 02 (single slides) 19.50 390.00FK 2821-2001-1 20 x 01 (single slides) 20.50 410.00FK 2821-2002-1 20 x 02 (single slides) 18.50 740.00

FI 2822-1001-1 G “Exanthema Profile 1” IgG 10 x 01 (test system) 27.90 279.00FI 2822-1002-1 G (consisting of 20 different substrates) 10 x 02 (test system) 25.10 502.00FI 2822-1001-1 M * IgM 10 x 01 (test system) 27.90 279.00FI 2822-1002-1 M * 10 x 02 (test system) 25.10 502.00FK 2822-1001-1 * 10 x 01 (single slides) 20.90 209.00FK 2822-1002-1 * 10 x 02 (single slides) 18.90 378.00

FI 2823-1001-1 G * “Lymphadenitis Profile 1” IgG 10 x 01 (test system) 29.70 297.00FI 2823-1002-1 G * (consisting of 20 different substrates) 10 x 02 (test system) 26.70 534.00FI 2823-1001-1 M * IgM 10 x 01 (test system) 29.70 297.00FI 2823-1002-1 M * 10 x 02 (test system) 26.70 534.00FK 2823-1001-1 * 10 x 01 (single slides) 22.30 223.00FK 2823-1002-1 * 10 x 02 (single slides) 20.10 402.00

FI 2824-1001-1 G “Central Nervous System Profile 1” IgG 10 x 01 (test system) 26.00 260.00FI 2824-1002-1 G (consisting of 20 different substrates) 10 x 02 (test system) 23.40 468.00FI 2824-1001-1 M * IgM 10 x 01 (test system) 26.00 260.00FI 2824-1002-1 M * 10 x 02 (test system) 23.40 468.00FK 2824-1001-1 * 10 x 01 (single slides) 19.50 195.00FK 2824-1002-1 * 10 x 02 (single slides) 17.60 352.00

FI 2825-1001-1 G “Myocarditis Profile 1” IgG 10 x 01 (test system) 22.20 222.00FI 2825-1002-1 G (consisting of 16 different substrates) 10 x 02 (test system) 20.00 400.00FI 2825-1001-1 M IgM 10 x 01 (test system) 22.20 222.00FI 2825-1002-1 M 10 x 02 (test system) 20.00 400.00FK 2825-1001-1 10 x 01 (single slides) 16.70 167.00FK 2825-1002-1 10 x 02 (single slides) 15.00 300.00

FI 2826-1001-1 G “Infectarthritis Profile 1” IgG 10 x 01 (test system) 15.70 157.00FI 2826-1002-1 G (consisting of 12 different substrates) 10 x 02 (test system) 14.10 282.00FI 2826-1001-1 M IgM 10 x 01 (test system) 15.70 157.00FI 2826-1002-1 M 10 x 02 (test system) 14.10 282.00FK 2826-1001-1 10 x 01 (single slides) 11.80 118.00FK 2826-1002-1 10 x 02 (single slides) 10.60 212.00

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

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Depending on the immunoglobulin class to be investigated, A, G or M appears behind the order number. Some test systems have not been evaluated for IgA or IgM.

*) Currently not available as IVD in the European Union.

FI 2826-1003-21 G “Infectarthritis Profile 21: The Tropics”IgG 10 x 03 (test system) 10.20 306.00FI 2826-1005-21 G upper row : 10 x 05 (test system) 9.80 490.00FI 2826-1003-21 M Chikungunya virus IgM infected cells EU 14 10 x 03 (test system) 10.20 306.00FI 2826-1005-21 M bottom row : 10 x 05 (test system) 9.80 490.00FK 2826-1003-21 Dengue virus infected EU 14 10 x 03 (single slides) 7.70 231.00FK 2826-1005-21 types 1 to 4 cells 10 x 05 (single slides) 7.40 370.00

FI 2827-1001-1 G “Gastrointestinal Tract Profile 1” IgG 10 x 01 (test system) 17.80 178.00FI 2827-1002-1 G (consisting of 12 different substrates) 10 x 02 (test system) 16.00 320.00FI 2827-1001-1 M IgM 10 x 01 (test system) 17.80 178.00FI 2827-1002-1 M 10 x 02 (test system) 16.00 320.00FK 2827-1001-1 10 x 01 (single slides) 13.40 134.00FK 2827-1002-1 10 x 02 (single slides) 12.10 242.00

FI 2828-1001-1 G “Accompanying Hepatitis Profile 1” IgG 10 x 01 (test system) 17.20 172.00FI 2828-1002-1 G (consisting of 11 different substrates) 10 x 02 (test system) 15.50 310.00FI 2828-1001-1 M IgM 10 x 01 (test system) 17.20 172.00FI 2828-1002-1 M 10 x 02 (test system) 15.50 310.00FK 2828-1001-1 10 x 01 (single slides) 12.90 129.00FK 2828-1002-1 10 x 02 (single slides) 11.60 232.00

FI 2829-1001-1 G “Ophthalmology Profile 1” IgG 10 x 01 (test system) 12.10 121.00FI 2829-1002-1 G (consisting of 8 different substrates) 10 x 02 (test system) 10.90 218.00FI 2829-1001-1 M IgM 10 x 01 (test system) 12.10 121.00FI 2829-1002-1 M 10 x 02 (test system) 10.90 218.00FK 2829-1001-1 10 x 01 (single slides) 9.00 90.00FK 2829-1002-1 10 x 02 (single slides) 8.20 164.00

FI 2830-1001-6 G * “STD Profile 1” IgG 10 x 01 (test system) 18.10 181.00FI 2830-1002-6 G * (consisting of 12 different substrates) 10 x 02 (test system) 17.20 344.00FI 2830-1001-6 M * IgM 10 x 01 (test system) 18.10 181.00FI 2830-1002-6 M * 10 x 02 (test system) 17.20 344.00FK 2830-1001-6 * 10 x 01 (single slides) 13.60 136.00FK 2830-1002-6 * 10 x 02 (single slides) 12.90 258.00

FI 2831-1001-1 G * “Pregnancy Profile 1” IgG 10 x 01 (test system) 12.10 121.00FI 2831-1002-1 G * (consisting of 8 different substrates) 10 x 02 (test system) 11.40 228.00FI 2831-1001-1 M * IgM 10 x 01 (test system) 12.10 121.00FI 2831-1002-1 M * 10 x 02 (test system) 11.40 228.00FK 2831-1001-1 * 10 x 01 (single slides) 9.00 90.00FK 2831-1002-1 * 10 x 02 (single slides) 8.60 172.00

FI 2832-1001-1 G “Otitis Profile 1” IgG 10 x 01 (test system) 23.80 238.00FI 2832-1002-1 G (consisting of 16 different substrates) 10 x 02 (test system) 21.40 428.00FI 2832-1001-1 M IgM 10 x 01 (test system) 23.80 238.00FI 2832-1002-1 M 10 x 02 (test system) 21.40 428.00FK 2832-1001-1 10 x 01 (single slides) 17.80 178.00FK 2832-1002-1 10 x 02 (single slides) 16.10 322.00

FI 2842-1003-1 G “Fever Profile 1: South East Asia” IgG 10 x 03 (test system) 18.30 549.00FI 2842-1005-1 G upper row : 10 x 05 (test system) 17.60 880.00FI 2842-1003-1 M Chikungunya virus IgM infected cells EU 14 10 x 03 (test system) 18.30 549.00FI 2842-1005-1 M Japanese encephalitis virus infected cells EU 14 10 x 05 (test system) 17.60 880.00FK 2842-1003-1 Plasmodium falciparum HRP-2 + MSP-2 Pl. falciparum 10 x 03 (single slides) 13.80 414.00FK 2842-1005-1 Plasmodium vivax MSP + CSP Pl. vivax 10 x 05 (single slides) 13.20 660.00

bottom row :Dengue virus infected EU 14types 1 to 4 cells

format 1003: slides with 3 patient profilesformat 1005: slides with 5 patient profiles

FI 2860-1005-1 P Candida albicans IgAGM fungal smear Candida albicans 10 x 05 (test system) 8.20 410.00FI 2860-2005-1 P Candida glabrata fungal smear Candida glabrata 20 x 05 (test system) 7.80 780.00FK 2860-1005-1 Candida krusei fungal smear Candida krusei 10 x 05 (single slides) 6.20 310.00FK 2860-2005-1 Candida tropicalis fungal smear Candida tropicalis 20 x 05 (single slides) 5.90 590.00

Candida parapsilosis fungal smear Candida parapsilosis(5 BIOCHIPs per field)

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

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Price (€)per Kit

Antibodiesagainst

Substrate Species FormatSlides x Fields

Order No. Price (€)per Field

Diagnostics for Indirect Immunofluorescence: Further Antigens

Ig Class

FV 2841-1003 A Saccharomyces IgA fungal Saccharomyces 10 x 03 (test system) 2.60 78.00FV 2841-1005 A cerevisiae smear cerevisiae 10 x 05 (test system) 2.50 125.00FV 2841-1010 A 10 x 10 (test system) 2.30 230.00FV 2841-2005 A 20 x 05 (test system) 2.40 240.00FV 2841-1003 G IgG 10 x 03 (test system) 2.60 78.00FV 2841-1005 G 10 x 05 (test system) 2.50 125.00FV 2841-1010 G 10 x 10 (test system) 2.30 230.00FV 2841-2005 G 20 x 05 (test system) 2.40 240.00FV 2841-1003 M IgM 10 x 03 (test system) 2.60 78.00FV 2841-1005 M 10 x 05 (test system) 2.50 125.00FV 2841-1010 M 10 x 10 (test system) 2.30 230.00FV 2841-2005 M 20 x 05 (test system) 2.40 240.00FX 2841-1003 10 x 03 (single slides) 2.00 60.00FX 2841-1005 10 x 05 (single slides) 1.90 95.00FX 2841-1010 10 x 10 (single slides) 1.70 170.00FX 2841-2005 20 x 05 (single slides) 1.80 180.00

FV 3011-1003 A gliadin IgA gliadin BIOCHIPs wheat 10 x 03 (test system) 3.20 96.00FV 3011-1005 A 10 x 05 (test system) 3.10 155.00FV 3011-1010 A 10 x 10 (test system) 2.70 270.00FV 3011-2005 A 20 x 05 (test system) 2.90 290.00FV 3011-1003 G IgG 10 x 03 (test system) 3.20 96.00FV 3011-1005 G 10 x 05 (test system) 3.10 155.00FV 3011-1010 G 10 x 10 (test system) 2.70 270.00FV 3011-2005 G 20 x 05 (test system) 2.90 290.00FX 3011-1003 10 x 03 (single slides) 2.40 72.00FX 3011-1005 10 x 05 (single slides) 2.30 115.00FX 3011-1010 10 x 10 (single slides) 2.10 210.00FX 3011-2005 20 x 05 (single slides) 2.20 220.00

Price (€)

per Kit

Antibodies

against

Substrate Species Format

Slides x Fields

Order No. Price (€)

per Field

Diagnostics for Indirect Immunofluorescence: Infectious Serology

Ig Class

FI 2861-1003 A Candida IgA fungal Candida 10 x 03 (test system) 2.60 78.00FI 2861-1005 A albicans smear albicans 10 x 05 (test system) 2.50 125.00FI 2861-1010 A 10 x 10 (test system) 2.30 230.00FI 2861-2005 A 20 x 05 (test system) 2.40 240.00FI 2861-1003 G IgG 10 x 03 (test system) 2.60 78.00FI 2861-1005 G 10 x 05 (test system) 2.50 125.00FI 2861-1010 G 10 x 10 (test system) 2.30 230.00FI 2861-2005 G 20 x 05 (test system) 2.40 240.00FI 2861-1003 M IgM 10 x 03 (test system) 2.60 78.00FI 2861-1005 M 10 x 05 (test system) 2.50 125.00FI 2861-1010 M 10 x 10 (test system) 2.30 230.00FI 2861-2005 M 20 x 05 (test system) 2.40 240.00FK 2861-1003 10 x 03 (single slides) 2.00 60.00FK 2861-1005 10 x 05 (single slides) 1.90 95.00FK 2861-1010 10 x 10 (single slides) 1.70 170.00FK 2861-2005 20 x 05 (single slides) 1.80 180.00

FI 293a-1005 G Chikungunya virus IgG infected and non- EU 14 10 x 05 (test system) 2.90 145.00FI 293a-1010 G infected cells 10 x 10 (test system) 2.60 260.00FI 293a-2005 G (2 BIOCHIPs per field) 20 x 05 (test system) 2.70 270.00FI 293a-1005 M IgM 10 x 05 (test system) 2.90 145.00FI 293a-1010 M 10 x 10 (test system) 2.60 260.00FI 293a-2005 M 20 x 05 (test system) 2.70 270.00FK 293a-1005 10 x 05 (single slides) 2.20 110.00FK 293a-1010 10 x 10 (single slides) 2.00 200.00FK 293a-2005 20 x 05 (single slides) 2.10 210.00

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ZZ 3000-0112 cover glasses 12 pieces 4.00ZZ 3000-0122 (embedding slides with 22 pieces 6.00

5 or 10 fields)

ZZ 3001-0112 cover glasses 12 pieces 10.00(for embedding slides

with 50 fields)

ZZ 9801-0101 incubated slide for 1 piece 10.00demonstration purposes

ZZ 9991-0110 slide tablet for 10 slides 3.50ZZ 9991-0120 for storage of incubated slides with up to 10 fields for 20 slides 5.00

ZZ 9991-0102-1 slide tablet for 2 slides 3.50ZZ 9991-0104-1 for storage of incubated slides with 50 fields for 4 slides 5.00

ZZ 9999-0105 reagent tray for for slides with 5 fields 25.00ZZ 9999-0110 the incubation of slides for slides with 10 fields 25.00ZZ 9999-0196 for slides with 96 fields 25.00

ZZ 9999-0150-1 reagent tray for the for slides with 50 fields 25.00incubation of slides with

1 BIOCHIP per field

ZZ 9999-0150-2 reagent tray for the for slides with 50 fields 25.00incubation of slides with2 to 4 BIOCHIPs per field

Price (€)Reagent FormatOrder No.

Further Reagents for EUROIMMUN IIFT

Price (€)Item FormatOrder No.

Other Items for EUROIMMUN IIFT

ZF 1020-0145 sample buffer (IIFT) 4.5 ml 10.50

ZF 1100-1000 salt for PBS, pH 7.2 1 pack 2.50(to be dissolved in 1 liter of distilled water)

ZF 1110-0102 Tween 20 2.0 ml 0.50ZF 1110-0120 (2.0 ml to be added to 1 liter of PBS) 20 ml 4.00

ZF 1120-0101 additive (exclusively) for CMV buffer 1 ml 0.50(1.0 ml as admixture for 1.0 liter PBS)

ZF 1125-1000 distilled water for PBS 1.0 l 5.00(only to be used with

EUROIMMUN test systems)

ZF 1130-0501 urea solution 5 M, 1.0 ml 2.50ZF 1130-0601 (for the determination of low-avide antibodies 6 M, 1.0 ml 2.50ZF 1130-0801 in infectious serology) 8 M, 1.0 ml 2.50

ZF 1140-0101 glycine urea buffer 1.5 ml 2.50

ZF 1150-0115 Evans Blue 1.5 ml 2.502% in PBS

ZF 1200-0103 embedding medium 3.0 ml 2.50ZF 1200-0120 (containing anti-bleaching reagent) 20 ml 12.50ZF 1200-0130 30 ml 15.00ZF 1200-0199 100 ml 30.00

ZF 1270-0145 EUROSORB for immunofluorescence 4.5 ml 46.00(liquid RF absorbent)

ZF 6110-0110 sorbent for FTA-ABS test for 1.0 ml 12.30ZF 6110-0150 (lyophilized) for 5.0 ml 61.50

ZF 9000-0000 human serum, frozen, lyophilisate for 0.05 ml 2.50ZF 9000-0001 as complement source lyophilisate für 0.15 ml 5.00ZF 9000-0002 lyophilized, lyophilisate für 0.25 ml 12.50

EBV antibody negative

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Products from EUROIMMUN AG will be delivered according to the following conditions, as long as no other conditions have been agreed inwriting. On issuing an order, the buyer acknowledges the delivery conditions. EUROIMMUN does not accept the sales conditions of thebuyer, even when EUROIMMUN has not expressly contradicted them. Contract terms are valid for all future business connection even if theyhave not been expressly agreed upon again.

Orders: Orders to EUROIMMUN can be made in writing (including electronic communication) or verbally. Verbally issued orders firstbecome legally binding for EUROIMMUN with a written confirmation from the orderer or with the delivery of goods.

Delivery: EUROIMMUN generally delivers to end users within 7 days of order receipt and to distributors within 14 days, but is not tied to anydefinite delivery period. If a delivery is not possible through unforseeable circumstances (e.g., factory disruptions, raw material deliverydelays, transport difficulties, strikes), the delivery obligation does not apply. EUROIMMUN reserves the right to deliver in part. The deliveryobligation of EUROIMMUN AG ceases as long as the customer is in arrears. EUROIMMUN chooses the packing and dispatching method at itsown discretion, according to the respective requirements.

Product characteristics: The delivered products comply with specifications given in the product catalogue, on the product itself, or in thesupplied information sheets. If specifications are inconsistent, the labels on the product itself and the details in the information sheetprovided with the product apply. After the given expiration date has passed, the test reagents must not be used.

EUROIMMUN products must only be used for the intended purpose. It is the buyer’s responsibility to check the functional capabilityimmediately on receipt of the product as well as on every day of usage. In particular, the functioning of test reagents can be perturbedthrough causes outside the direct influence of the maunfacturer, for example, through suboptimal transportation, incorrect storage, orincorrect usage. When test reagents delivered from EUROIMMUN are used, the user must supervise the analysis with appropriate proficiency.

Warranty and liability: If nothing else has been agreed upon in writing, all risks pass to the buyer as soon as the goods have been deliveredto the carrier or has left EUROIMMUN AG premises for dispatch. With notification of dispatch by EUROIMMUN the risk passes to the buyer ifthe delivery is postponed or delayed by request of the buyer. On receipt of the goods, the buyer has one working day to check if they are inaccordance with the nature and quantity of the agreement and if the goods are free from visible defects. If any complaints arise from thisinspection, they should be communicated to EUROIMMUN AG in writing within 2 working days. Hidden defects or functional faults that werenot identifiable with the initial inspection and are later discovered should be communicated to EUROIMMUN AG in writing within 14 days ofreceipt of the goods. If no complaints are received within the stipulated period, it is assumed that the goods are of appropriate quality andquantity for the customer. Complaints do not release the buyer from payment obligation.

With prompt and reasonable complaints on the grounds of product defects or the delivery of something other than the ordered goods,EUROIMMUN is obliged to exchange or amend the goods within 14 days or to withdraw or reimbourse the payment, as it chooses. If thedefect is not corrected in spite of delivery of a replacement or an amended product, the buyer can demand that the sale is cancelled.

If defects are promptly reclaimed, EUROIMMUN has the choice between a further delivery or an appropriate credit note. Further compensatoryclaims from the buyer are excluded, as long as EUROIMMUN has not violated its contractual or legal obligations through outright negligenceor by intention. In such cases EUROIMMUN provides compensation of up to a maximum of 20 times the price of one packet (test kit) of thedefective product. EUROIMMUN takes no responsibility for any damage resulting from faulty goods.

Prices: Prices from the official EUROIMMUN pricelist in the country of the buyer are applicable. Invoices are provided in the agreed currency.Prices are “ex works”. Costs for packing and freight as well as for cooling during transport are added on. Statutory value added tax is notincluded in the list prices.

Payment terms: Payment obligations in countries of export must be settled within 30 days after recieving the goods. No cash discounts willbe given unless agreed in writing. Payments by cash transfer or check are valid from the timepoint that the invoice amount is credited to aEUROIMMUN AG bank account. In cases of payment arrears, EUROIMMUN reserves the right to charge compensatory interest of 10% p.a.,applicable from the settlement date, without any further notice. In special cases EUROIMMUN can arrange alternative payment periods ordemand advance payments. EUROIMMUN’s demands resulting from an order cannot be offset by the customer through counter demands.

Ownership rights: The delivered goods remain the property of EUROIMMUN AG until full payment. Selling on of EUROIMMUN products isonly permitted for companys who are authorized in writing from EUROIMMUN to do so. Software received from EUROIMMUN should not bepassed on to third parties without written permission from EUROIMMUN AG.

Consultation: Advice from EUROIMMUN AG, although provided to the best knowledge, is nevertheless not binding. No liability claims canensue from erroneous advice.

Applicable law, place of jurisdiction, ineffective regulations: The contract conditions are subject to the laws of the Federal Republic ofGermany. The United Nations Conventions on Contracts for the International Sale of Goods does not apply. The place of jurisdiction andfulfilment is Luebeck. If any provision of these general delivery conditions will be held invalid or unenforcable, this general delivery conditionwill not be rendered invalid as a whole, and the provisions will be changed and interpreted so as best to accomplish the objective of theunenforcable or invalid provision.

General Delivery Conditions

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Index

Autoantibody Diagnosticsacetylcholine receptor (ACHR) .............................................................................. 12, 17, 84Actin ....................................................................................... 16-17, 32, 38, 45, 64, 125, 132adrenal cortex ........................................................................................... 13, 17, 43, 62, 120AMA . 6, 13, 16-17, 26, 32-34, 37-40, 43, 45, 64, 72, 74-75, 82-83, 120, 125-126, 128-133ANA ...................... 14, 16-17, 26, 32-35, 37-38, 41, 44-45, 64, 76, 82, 122-127, 129-133ANCA ............................................... 12-14, 16-17, 32, 44-45, 62-63, 81, 122-124, 126-127ASCA .................................................................................... 15, 17-18, 71, 87, 95, 124, 150ASMA .................................................................................... 12, 16-17, 38, 64, 125, 131-133Autoantibody Profile 2 ....................................................................................................... 121Automated solutions ........................ 4, 8, 22, 26, 28, 33, 39, 41, 49, 51-53, 58, 155-156basement membranes .......................................................... 12, 14, 16-17, 63, 76, 81, 128ß2-glycoprotein ..................................................................................................................... 83bile ducts .......................................................................................................................... 17, 32BPI ......................................................................................................................... 17, 44-45, 81brain .......................................................................................................... 12, 17, 62, 120-121C1q .............................................................................................................................. 16, 81, 83cANCA ....................................................... 12, 16-17, 32, 44-45, 62, 81, 122-124, 126-127cardiolipin (AMA M1) ................................................................................... 16-17, 79, 82-83cartilage ......................................................................................................................... 16, 128cathepsin G ......................................................................................................... 17, 44-45, 81cell nuclei (ANA global test) ................................................................................. 32-35, 129centromere ..................................................................................... 14, 16, 32, 34, 45, 64, 82cerebellum ...................................................................................... 12-14, 41-42, 78, 120-122circulating immune complexes (CIC) .......................................................................... 16, 83cyclic citrullinated peptide (CCP) ........................................................................ 16, 36, 81Cyclin I (PCNA) .................................................................. 12, 16, 26, 32-33, 45, 64, 76, 82Cyclin II (Mitosin) ..................................................................................................... 12, 45, 64cytoplasm of granulocytes ...................... 12-14, 16-17, 44-45, 62-63, 80, 120-122, 124desmosomes .................................................................................................... 12, 17, 63, 128dsDNA ...................... 6, 12, 16-17, 26, 32-35, 38, 41, 45, 64, 74-75, 81-82, 84, 131-132elastase ................................................................................................................ 17, 44-45, 81elastin ................................................................................................................... 12, 16-17, 65ENA ................................................................................................... 16, 24, 32, 34, 75-76, 82endomysium ...................................................................... 12, 17, 32, 46, 65, 83, 133-136endothelial cells ................................................................... 12-13, 16-17, , 32, 62, 65, 136epidermis ............................................................................................ 12-13, 17, 36, 63, 128EUROIMMUN Analyzer I ............................................................................................. 22, 155EUROLineScan ..................................................... 4, 26, 28, 33, 39, 41, 49, 51-53, 58, 155EUROPLUS . 3, 7, 32, 37-38, 40, 44, 46, 48, 120, 124-126, 129-131, 134-135, 138-139, 144EUROStar .................................................................................................................. 8, 155-156eye antigens ......................................................................................................................... 122F-actin ....................................................................................................... 17, 38, 64, 125, 132GAD .......................................................................................... 12, 17, 41-42, 62, 81, 84, 120Gangliosides .................................................................................................................... 17, 76gliadin ................................................................. 12, 17, 46, 65, 72, 89, 98, 134-135, 154glomerular basement membrane (GBM) ............................... 12, 17, 63, 76, 81, 124-125glutamat-decarboxylase ................................................................ 12, 17, 41-42, 62, 81, 84Golgi apparatus .......................................................................................... 12, 16, 32, 45, 64Goblet cells ...................................................................................... 12, 17, 63, 127-128, 130heart muscle .......................................................................................... 12, 17, 38, 125, 130HEp-2-cells .................................. 6, 12-14, 32-33, 35, 37-38, 44-45, 78, 122-125, 129-133histones ...................................................................... 6, 12, 16, 26, 32-34, 45, 75-76, 81-82Hu ........................................................................................... 12, 17, 41, 62, 76, 78, 120-122HUVEC ................................................................................................................................... 136hypothalamus antigens ....................................................................................... 12, 17, 121IA-2 ....................................................................................................................... 17, 42, 81, 84Insulin .................................................................................................................. 17, 42, 84, 91intestinal goblet cells ............................................................................. 12, 17, 63, 126-127intrinsic factor .................................................................................. 13, 17, 43, 63, 81, 126Jo-1 ............................................ 13, 16, 24, 26, 32-34, 45, 64, 75-76, 78, 82-83, 129-130keratin ................................................................................................... 13, 16-17, 36, 63, 128Ku ..................................................................................................... 13, 16, 33, 45, 64, 76, 78lactoferrin ............................................................................................................ 17, 44-45, 81LC-1 ............................................................................................ 17, 32, 38-39, 75-76, 81, 125Leydig cells .............................................................................................. 17, 43, 62, 120-121liver-kidney microsomes (LKM) ............................. 13, 17, 32, 37-39, 63, 75-76, 81, 125liver-specific antigens ................. 6, 13, 16-17, 26, 32-34, 37-39, 64, 75-76, 81-83, 125LKM-1 ................................................................................ 13, 17, 32, 37, 39, 75-76, 81, 125lung alveoli .................................................................................................................... 17, 125lymphocyte antigens ........................................................................................... 13, 17, 124M2 ag (AMA-M2) ... 6, 16-17, 19, 26, 33-34, 37-39, 64, 72, 75-76, 82-83, 125, 131-132M4 antigen .................................................................................................. 13, 17, 32, 37, 75M9 antigen ............................................................................................ 13, 17, 32, 37, 64, 75Mab .................................................................................................................... 17, 40, 62, 120MAG ..................................................................................................................... 13, 17, 41, 62Mi-2 ......................................................................................................... 13, 16, 33, 45, 76, 78mitochondria (AMA) 6, 13, 26, 32, 34, 37-40, 43, 45, 64, 72, 75-76, 82-83, 120, 125-133mitosin ....................................................................................................................... 12, 45, 64myelin ............................................................................................................. 12-13, 17, 41, 62myeloperoxidase (MPO) ................................................ 13, 17, 44-45, 63, 75-76, 81, 124nDNS ........................ 6, 12, 16-17, 26, 32-35, 38, 41, 45, 64, 75-76, 81-82, 84, 131-132nerves ........................................................................................... 12-14, 17, 41, 62, 121-122neuronal autoantibodies .............................................. 12, 14, 17, 41, 62, 76, 78, 120-122nRNP/Sm .............................................................. 16, 24, 26, 32-34, 45, 74-75, 82, 129-130nuclear membrane ............................................................................................ 17, 32, 45, 64nucleosomes ............................................................................... 16, 32-35, 45, 75-76, 81-82oesophagus ............................................................................... 12-13, 36, 46, 128, 133-135ovarial antigens ............................................................................................................ 43, 120P/Q calcium channel (VGCC) ........................................................................................ 17, 82pANCA ....................................................... 13, 16-17, 32, 44-45, 63, 81, 122-124, 126-127pancreas islets ............................................................. 12, 42-43, 63, 81, 122-124, 126-127parathyroid gland ................................................................................................... 13, 17, 120parietal cells (PCA) .................................................................. 12, 43, 63, 81, 120, 125-126parotid gland excretory ducts and acini ............................................. 13-14, 17, 63, 127PCNA (Cyclin I) .................................................................. 12, 16, 26, 32-33, 45, 64, 76, 82phosphatidylserine ................................................................................................... 16-17, 81phospholipids ................................................................................................ 16-17, 79, 82-83pituitary gland antigens ...................................................................................... 12, 17, 121PL-12 ............................................................................................................. 16, 33, 45, 76, 78PL-7 ............................................................................................................... 16, 33, 45, 76, 78placenta ............................................................................................................ 14, 17, 62, 121PM-Scl ............................................................................. 6, 16, 26, 32-34, 45, 75-76, 78, 82proteinase 3 (capture test) ............................................................................................ 44, 81proteinase 3 (PR3) ................................................................. 14, 17, 44-45, 75-76, 81, 124renal glomeruli (GBM) .............................................................. 12, 17, 63, 76, 81, 124-125

reticulin ............................................................................................................ 14, 17, 133-135retina .................................................................................................................. 13-14, 17, 122rheumatoid factors ......................................................................................................... 36, 56Ri ............................................................................................ 14, 17, 41, 62, 76, 78, 120-122RIA .......................................................................................................... 30, 35, 40, 42, 81-83ribosomal P-proteins ................................................................................. 14, 16, 32, 64, 82RNS-Polymerase ............................................................................................... 14, 16, 32, 45Ro-52 ......................................................................... 16-17, 26, 32-34, 39, 45, 75-76, 78, 82saccharomyces cerevisiae ....................................... 15, 17-18, 72, 89, 97, 126-127, 154Scl-70 ...................................................... 14, 16, 24, 26, 32-34, 45, 64, 75-76, 82, 129-130skeletal muscle ........................................................................ 12-14, 17, 38, 125, 127, 130SLA/LP ................................................................................ 17, 32, 38-39, 72, 75-76, 81, 125Sm .......................................................... 14, 16, 24, 26, 32-34, 45, 64, 75-76, 82, 129-130smooth muscles .................................................................. 12, 16-17, 38, 64, 125, 131-133Sp100 ............................................................................................... 16-17, 38-39, 64, 76, 125spermatozoa .................................................................................................... 14, 17, 62, 121spindle fibers ..................................................................................................... 16, 32, 45, 64SS-A ...................................... 6, 14, 16-17, 24, 26, 32-34, 45, 64, 75-76, 78, 82, 129-130SS-B ............................................. 6, 14, 16-17, 24, 26, 32-34, 45, 64, 75-76, 82, 129-130ssDNA ................................................................................................. 14, 16-17, 34, 45, 80-82TAb ..................................................................................................................... 17, 40, 62, 120testis ............................................................................................ 14, 17, 40, 43, 62, 120-121thrombocyte antigens ................................................................................... 14, 17, 63, 124thyroglobulin (TG) ........................................................ 14, 17, 40, 43, 62, 75, 81, 84, 120thyroid gland .......................................................... 13-14, 17, 40, 43, 62, 75, 81, 84, 120thyroid peroxidase (TPO) ................................................................................ 40, 75, 81, 84TRAb .................................................................................................................... 17, 40, 81, 84transglutaminase ...................................................................................................... 17, 46, 83U1-nRNP ............................................................................................................. 14, 16, 64, 82vascular endothelium ........................................................................................................... 65Vimentin ....................................................................................................... 14, 16, 32, 45, 64Yo ........................................................................................... 14, 17, 41, 62, 76, 78, 120-122

Infectious serologyAdenovirus ................................................................................... 15, 18, 54-55, 71, 88, 148Afipia felis ............................................................................................................... 15, 18, 67Automated solutions ...................... 4, 8, 22, 26, 28, 33, 39, 41, 49, 51-53, 58, 155-156Bartonella ........................................................................................... 15, 18, 54, 67-68, 142Bordetella ................................................................................................. 15, 18, 54, 66, 137Borrelia ...................................... 15-18, 21, 28, 48-49, 54-55, 66-67, 73, 79, 85, 138-139Brucella abortus .................................................................................................................... 86Campylobacter ......................................................................................... 15, 18, 55, 66, 137Candida ............................................................................... 15, 18, 54-55, 72, 109, 153-154Chlamydia ........................................................................ 15-16, 18, 54-55, 67, 86, 141-142Coxsackie virus .......................................................................... 15, 18, 54-55, 71, 149-150Cytomegalovirus (CMV) .......................... 15, 18, 21, 54-55, 69, 77, 80, 87, 144-145, 157Dengue virus ........................................................................................... 15, 70, 88, 147, 153EBNA ....................................................................................... 15, 18, 50-51, 77, 89, 151-152EBV-CA ................................................ 7, 15, 18, 21, 50-51, 54-55, 71-72, 88-89, 151-152EBV-EA ....................................................................... 7, 15, 18, 50, 54-55, 72, 89, 151-152Echinococcus granulosus ................................................ 15, 18, 55, 68, 79, 86, 112, 144Echo virus ........................................................................................... 15, 18, 54-55, 71, 150Epstein-Barr virus capsid ag ... 7, 15, 18, 21, 50-51, 54-55, 71-72, 77, 88-89, 151-152EUROIMMUN Analyzer I ............................................................................................. 22, 155EUROLineScan ..................................................... 4, 26, 28, 33, 39, 41, 49, 51-53, 58, 155EUROPLUS . 3, 7, 32, 37-38, 40, 44, 46, 48, 120, 124-126, 129-131, 134-135, 138-139, 144EUROSORB IgG/RF-Absorbens ............................................................................ 56, 60, 157EUROStar .................................................................................................................. 8, 155-156Haemophilus influenzae ......................................................................... 15, 18, 54, 66, 137Helicobacter pylori ...................................................... 15, 18, 52, 55, 65, 73, 79, 85, 137Herpes simplex (HSV) ......................................... 15, 17-18, 53-55, 69, 74, 80, 86-87, 145HHV-6 ......................................................................................................... 15, 18, 54, 69, 144HIV .................................................................................................. 15, 18, 54-55, 68-69, 144Influenza virus ...................................................... 15, 18, 54-55, 66, 71, 88, 137, 148-149Klebsiella pneumoniae ..................................................................... 15, 18, 54-55, 66, 137Legionella ................................................................................... 15, 18, 54, 67, 85, 140-141Leishmania ....................................................................................................... 15, 18, 68, 143Listeria .............................................................................................. 15, 18, 54, 67, 139-140Measles virus ................................................................. 15, 18, 21, 54-55, 60, 68, 87, 146Mumps virus ......................................................................... 15, 18, 21, 54-55, 66, 87, 146Mycoplasma ................................................................................. 15, 18, 54-55, 68, 86, 143Parainfluenza virus ..................................................................... 15, 18, 54-55, 71, 88, 149Plasmodium .......................................................................................................... 77, 144, 153Reiter spirochetes ................................................................................................................. 66Respiratory syncytial virus (RSV) ................................................. 15, 18, 54, 70, 88, 147Rubella virus ...................................................... 7, 15, 18, 21, 54-55, 69, 77, 87, 144-145SARS coronavirus ................................................................................................ 69, 87, 146TBE virus ................................................................. 15, 18, 21, 48-49, 70, 87-88, 146-147Toxoplasma gondii ................................................... 7, 15, 18, 21, 54-55, 68, 77, 86, 144Treponema pallidum ................................................................... 15, 18, 54, 66, 73, 79, 85Ureaplasma urealyticum .............................................................................. 15, 18, 68, 143Varicella zoster virus (VZV) ................................................ 15, 18, 21, 54-55, 70, 87, 146VlsE .................................................................................. 15, 28, 48-49, 67, 79, 85, 138-139West-Nile virus ............................................................................ 7, 15, 21, 70, 88, 146-147Yersinia enterocolitica ............................................ 15-16, 18, 55, 67, 73-74, 79, 85, 141

Allergologyanimal allergens ........................................................................................................ 19, 93-95automated solutions ......................... 4, 8, 22, 26, 28, 33, 39, 41, 49, 51-53, 58, 155-156environmental allergens ...................................................................................... 19, 114-116EUROIMMUN Analyzer I ............................................................................................. 22, 155EUROLineScan ..................................................... 4, 26, 28, 33, 39, 41, 49, 51-53, 58, 155food ......................................................................................................... 19, 58, 76-78, 96-106further allergens .................................................................................................................. 111grasses ............................................................................................................. 19, 58, 106-108herbal and flower pollen ....................................................................... 19, 58, 99, 117-119house dust ..................................................................................................................... 19, 108insects ....................................................................................................... 19, 58, 78, 108-109mites .................................................................................................................. 19, 58, 93, 108moulds .................................................................................................................... 19, 109-111parasites ................................................................................................................... 18-19, 112pharmaceutical drugs .............................................................................................. 19, 90-92trees ......................................................................................................................... 19, 112-114

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D-23560 Luebeck (Germany) · Seekamp 31 · Telephone: +49 451 58550 · Fax: +49 451 5855591 · [email protected]

Primate pancreas: Autoantibodies against islet cells in diabetes mellitus.