A d v a n c e d a l g o r i t h m s f o r l i f e s c i e n c e s

生命科学的高级算法专业

Stefano Piotto – CEO – Associate Professor University of Salerno

ETH Zurich – Univ. of Balearic Islands – Board of AI Italian associationpublications on www.researchgate.net/profile/Stefano_Piotto/info

Lucia Sessa – CTO Drug design - PhD Luigi Di Biasi – CTO Software dev

Team

AI platform

2

Finance

CROs

Manufacturing

CROs

Tools dev

4 + fl

Synthesis

2

Board experts

5

Drug design

3

TECH IN TOUCH

FOUNDATION

NETWORKS

CONTRACTS

2019 - Salerno

SJT Molecular Research Sl

EIT Health

Tecnocap Spa

SOFTMINING IN A NUTSHELL

Enrich China

Expand Digital Partners

Sitem-Insel

Numaferm

Biovista

SoftMining – 2020 Confidential

Synth

AI

Drug designMoANetwork analysisPeptide design

High througput synthesisMicroliters reactionsDirect screeningRetrosynthesis assisted

Novel algorithmsSemantic searchAugmented MDNeural networks for DG prediction

WHAT SOFTMINING IS ALL ABOUT

SoftMining – 2020 Confidential

Robot

Robotics for synthesis, materials preparations, microbiological tests

THE PLUS IS AT THE INTERFACE

Discovery phase Pre-Clinical Phases Clinical Testing Commercial Phase

14 years

COSTS 219 M€ 62 M€ 592 M€ 873 M€(out-of-pocket) 25% 17% 68%

S.M. Paul et al, 2010, How to improve R&D productivity: the pharmaceutical industry’s grand challenge, Nature

THE PROBLEM OPPORTUNITY

Value

DRUG DISCOVERY

ANTICANCER

Anticancer drug active on SMS. Clinical phase Iib

More info www.clinglio.eu

ANTIBIOTICS

AI model for prediction antimicrobial peptidesTwo novel peptides active against specific gram+ Bacteria

Patent pending

AI PLATFORM

Multipurpose platform for drug design. The first platform that

combines the calculation phase and the processing phase of

the results

HIGH THROUGHPUTSYNTHESIS

Automatic robot assisted chemical synthesis. Using technologies

developed in the university environment it will be possible to

realize hundreds of reactions

Potential anticancer drug active on ADAR

(epitranscriptomics)

Biodegradable material optimized (patent pending)

SoftMining – 2020 Confidential

SEMANTIC ANALYSES

Semantic analysis of documents

ELECTROCARDIOGRAM ANALYSES

Semantic analysis of electrocardiograms (ECG)

Application for hyperthropia, and arrhythmiaSupported by

Semantic search engine

WIT

HEALTH

BIG DATA

AI based assistant for traveling Supported by

SM-Covid-19

The first contact tracing app using BLEAvailable at

HOW THE APP WORKS

SoftMining – 2020 Confidential

SOFTMINING IN A NUTSHELL

SoftMining – 2020 Confidential

𝑅𝑖𝑠𝑘(𝑡, ∆𝑡, 𝑓) =

𝑖

𝑛

𝑃𝑟𝑜𝑏(𝑖)

RISK CALCULATIONS

Under patent evaluation Under patent evaluation

Areas of potential risk can be identified on the basis of the geolocation of people and their associated risk can be identified

Which is the safest port dock to unload the goods?

EXAMPLE OF USE - HARBOR

Which industrial shed is safer to resume production?

EXAMPLE OF USE – INDUSTRIAL SHEDS

Compliant to individual privacy standards – GDPR

Auto-calibration(www.softmining.it/index.php/sm_covid19-dispositivi-supportati/)

User interface

BONUS

SoftMining – 2020 Confidential

More info @ www.softmining.it

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