Practical of Clinical Hematology

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Practical of Clinical Hematology. RBCs Morphology. Lab 2. RBCs Abnormal morphology. Peripheral Blood Morphology. Abnormal erythrocyte morphology. Is found in pathological states that may be abnormalities in Red cell distribution. Size (anisocytosis). - PowerPoint PPT Presentation

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<p>Objectives</p> <p>Practical of Clinical HematologyLab 2RBCs MorphologyRBCs Abnormal morphologyPeripheral Blood MorphologyAbnormal erythrocyte morphologyIs found in pathological states that may be abnormalities in Red cell distribution.Size (anisocytosis).Hemoglobin content Color Variation .Shape (poikilocytosis).The presence of inclusion bodies in erythrocyte.Erythrocyte Distribution AbnormalitiesRouleaux formationStacking of RBCs due to increased plasma proteins coating RBCs (resembling a stack of coins)Found in:- Hyperfibrinogenaemia- Hyperglobulinaemia</p> <p>AgglutinationAntibody-mediated Irregular clumping , temperature dependentFound in:- Cold agglutinins- Warm autoimmune hemolysis2</p> <p>Variation in erythrocyte size (anisocytosis)Anisocytosis: Variations in size (Microcyte and Macrocyte) </p> <p>Normocytic RBCs Normal size of RBC (8 m) with a range of 7 to 9 m. The nucleus of a small lymphocyte ( 8 m) is a useful guide to the size of a red blood cell).</p> <p>MicrocyticRBC cell smaller than the normal RBC ( </p>