Post Menopausal Osteoporosis in Egypt

Current Status

Osteoporosis

Our Patients

18000 Egyptian

Postmenopausal ladies

11096Rural

6904Urban

CAIROMeet HalfaEl Ahraz

Shebin El Kom Kom Berra.El bagour.

MansouraTalkhaBerken

Beni SwiefSedsEl Fashn

El MenyaMaghaghaBayaho

Parameters investigated

• Body: Height & weight

• Family income.

• Level of education.

• Physical exercise.

• Smoking.

• BMD.

• Fractures.

They were all

•Age 60-80 years

•Ambulatory

•Signed an informed Consent

•At least 5 years postmenopausal

•Risk Factor Assessment…Through a structured Questionnaire during the

participant interview

•Education

•Weight at 25 years

•Fractures since 50 years old

•Physical activity

•Socioeconomic Classification

Osteoporosis of the Lumbar Spine

T-score -4

Osteoporosis of the Femur Neck

T-score -2.7

Assessment of Fractures

•Radiologically performed

ResultsResults

The mean age and age at menopause and their distribution

AgeValueMean age (years)66.1 ± 4.6 years

Age at menopause50.8 ± 0.87

Age < 65 years678637.3%

Age > 65 years1121462.3%

The percentage of level of education

Level of educationNo.(%)

Less than a preparatory school including Illiterates(%)

1252869.6

High-school (Preparatory-Secondary) graduate(%) 310517.25

University Graduates(%) 236713.15

69.60%

17.25% 13.15%

0.00%

20.00%

40.00%

60.00%

80.00%

Less than a preparatory school including Illiterates (%)

High-school (Preparatory-Secondary) graduate (%)

University Graduates (%)

The Incidence & Distribution Of Monthly Income

Monthly incomeEgyptian pound

Freq.%

100-300 LE500427.8%

300-500 LE1137662.3%

500-1000 LE12156.75%

>1000 LE5673.15%

27.80%

62.30%

6.75%3.15%

0.00%

20.00%

40.00%

60.00%

80.00%

Monthly Income

100-300 LE 300-500 LE 500-1000 LE >1000 LE

The mean height and weight

Mean ± SD

Weight (Kg)73.53 ±

3.68

Height (Cm)154.6 ± 5.8

Average weight gain since age of 25 years

21.95 ± 5.8

Average height at age of 25 (cm)

157.5 ± 1.14

73.53

154.6

21.95

157.5

-10

10

30

50

70

90

110

130

150

170

Mean

Weight (Kg)Height (Cm)

Average weight gain since age of 25 years Average height at age of 25 (cm)

Repartition of the Participants (total 18000) according to their BMD status

NormalOsteopenicOsteoporotic

%%%

Femoral Neck

277215.4%966653.7%556230.9%

Lumbar Spine

712839.6%689438.3%397822.1%

Both Sites10896.05%1117862.1%572431.8%

309

1073

618

793765

442

121

1243

636

0

200

400

600

800

1000

1200

1400

Femoral Neck Lumbar Spine Both Sites

Normal Osteopenia Osteoporosis

The prevalence of vertebral fractures at baseline

NormalOsteopenicOsteoporoticAll

No.%No.%No.%No.%

1-3 fracture908.26%6305.63%113419.8%185410.3%

<3 fractures90.82%450.402%2524.4%3061.7%

All Fractures999.09%6756.03%138624.2%216012%

Total number108911187277215048

10

70

126

15

28

11

75

154

0

20

40

60

80

100

120

140

160

1-3 fractures > 3 fractures

Normal Osteopenic Osteoporotic

Distribution of Smoking History in urban and rural populations

UrbanRuralTotalχ2p

Smoking

Current198234432

0.010.996 Previous360441801

Negative7578919816761

Total8136986418000

Distribution of smoking status and BMD among Urban and Rural populations

Smoking NormalOsteopeniaOsteoporosisχ2P

CurrentUrban907236

0.0490.98Rural728136

PreviousUrban10817181

0.0540.975Rural126207108

NegativeUrban29748152223

00.998Rural36058412997

Distribution of monthly income in relation to BMD in urban and rural populations

IncomeNormalOsteopeniaOsteoporosisTotalχ2P

Urban

100-3009081913592268

397.1<0.001

300-50054398710265067

500-1000270162117549

<1000819081252

Total495505825838163

Rural

100-30010899016382736

476.8<0.001

300-50063483312516147

500-1000324198144666

<100099108108315

Total594612931419864

Distribution of monthly income in relation to BMD in urban and rural populations

Distribution of Exercise in urban and rural populations

UrbanRuralTotalχ2p

Exercise

Positive341141317542

00.957 Negative4725573310458

Total8136986418000