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PERSONNEL PLACEMENT
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Annemarie VisEuropean Recruitment AdvertisingTelephone: +44 223 302067FAX: +44 223 302 068
POSITIONS OPEN
MOLECULAR-CELLULAR NEUROSCIEN-TISTS. The Neuroscience Program at the Loeb Re-search Institute and the Division of Neurology at theOttawa Civic Hospital, a University of Ottawa teachinghospital, is seeking 2 qualified candidates, one at theASSISTANT PROFESSOR level (Ph.D. and/or M.D.with at least 3 years of postdoctoral training), and one atthe level ofESTABLISHED INVESmATOR (withan internationally comptiive track record). Candidatesmust demonstrate excellence, originality and productivityin molecular and/or cellular neurobiology. You will joina program whose clinical foci in stroke/ischemia anddegenerative/movement disorders are supported by aneuroscience research group (8 Prs) who use cell andmolecular biology and electrophysiology to study cell-cellcommunication and neurotransmission, membrane traf-ficking, mechanisms of neuron/glia response to ischemia,CNS regulation of hydromineral and cardiovascular ho-meostasis. Preference will be given to applicants usingmolecular approaches directd to postreceptor signaltransduction. In accordance with Canadian immigrationregulations, this advertisement is directedfirst, but not solely,to Canadian citizens and permanent residents.
Please forward curriculum vitae with names of threereferences and a statement of goals/interests by Septem-ber 30, 1993, to: Dr. Leo Renaud, Director, Neurol-ogy/Neurosciences, Ottawa Civic Hospital and LoebReserch Institute, 1053 Carling Avenue, Ottawa,Ontario, CANADA K1Y 4E9. We support Equal Op-portunity and a smoke-free environment.
ASSISTANT PROFESSORORVISITING PRO-FESSOR OF MEDICINAL CHEMISTRY/CHEMO-THERAPY. Ohio Northern University is advertising anine-month, tenure-track position. The position may also befilled by a Visiting Assistant Professor for the 1993-4academic year. The individual will be responsible for theteaching of appropriate areas ofMedicinal Chemistry, Che-motherapy, and/or Biochemistry to undergraduate pharma-cy students. Individual or collaborative research appropriateto the research mission of the Collee is also expected. APh.D. in Bio- or Medicinal Chemistiy is required. Anundegrad degree in pharmacy is desirable, but notrequired The application and selection process begins im-mediawpy.hcation deadline is July 17, 1993, or until asuitable te is identified. Application and i
should be sent to: Thomas P. Fad, Ph.D., Prfsand Chair, D rtment of Pharmaceuical and Biomed-ical Sciencs, C gc ofPharmacy, Ohio Northern Uni-versity, Ada, OH 45810. Equal Opportunity/AfnrmativeAction Employer. Women and minorities are encouraged to apply.
EVOLUTIONARY BIOLOGISTPrinceton University invites applications for a tenure-
track position in the Department of Ecology and Evolu-tionary Biology. We anticipate the position at thelevel ofASSISTANT PR F but a more seniorappointment is possible for truly exceptional candidates.We are particularly interested in receiving applicationsfrom ividuals using modern approaches to studyevolutionary mechanisms, either phylogenetic processesof diversification or the genetic basis of microevolution.Applicants should have a strong commitment to teachingand awell-developed conceptual basis to their research. Astatement of research interests, reprints of three publica-tions and three letters ofrecommendation should be sentto: Dr. Peter R. Grant, Department of Ecology &Evolutionary Biology, Guyot Hall, Princeton Univer-sity, Princeton, NJ 08544-1003. The closing date forapplications is September 4, 1993. Princeton University isan Affirmative Action/Equal Opportunity Employer.
BIOLOGICAL OCEANOGRAPHERWe seek a Ph.D. marine microbial ecologist for a
9-month, tenure-track position at the ASSISTANTPROFESSOR level to begin in August 1994. Theposition involves research, teaching at the graduate andundergraduate levels, and service. Applicants may haveresearch interests in the microbes of either the watercolumn or the benthos. Send a letter describing researchinterests, curriculum vitae, and the names, addresses andtelephone numbers of three references to: Search Com-mittee, Department of Oceanography, Florida StateUniversity, Tallahassee, FL 32306. Application reviewwill begin in July 1993 and continue until a suitablecandidate is found. The university is an Equal Opportuni-ty/Affirmative Action Employer.
POSITIONS OPEN
ASSOCIATE OR FULL PROFESSOR, GENET-IC/MOLECULAR MECHANISMS OF DISEASE.The Department of Comparative Medicine, Schools ofMedicine and Dentistry, University of Alabama at Bir-mingham (UAB), invites applications for a tenure-trackposition at the rank of Associate or Full Professor. Weseek an independent investigator of genetic and molecu-lar mechanisms in disease pathogenesis, with a strongcommitment to development and use of animal modesofhuman diseases. Investigators using novel approachesto gene transfer and expression, development of newembryonic stem cell systems (e.g., rat or rabbit), im-proved gene knockout or other innovations in animalmodeling are encouraged to apply. Teaching responsibil-ities are modest and primarily at the graduate level. TheDepartment of Comparative Medicine cosponsors withthe Department of Pathology the Graduate Program inMolecular and Cellular Pathology, and has an NIH-funded training program. UAB is a research intensiveuniversity ranked 17tl in NIH funding. Send curriculumvitae to: J. Russell Lindsey, Chair, Dexarmt ofCompartve Medicine, Schools of Medicine and Den-tistry, UAB, Birmingham, AL 35294-0019. UAB is anEqal Opportunity/AfirmxativoeAction Employer.
PLANT MOLECULARBIOLOGIST/GENETICISTThe University ofALBERTA
Departments of BOTANY and GENETICSNSERC Women's Faculty Award
The University of Alberta invites applications fromualified female researchers for potential nomination toteNatural Sciences and Engineering Research Council(NSERC) for Women's Faculty Award. In particular,applications are sought in the areas of Plant MolecularBiology and Plant Genetics. Applicants must have aPh.D. and postdoctoral experience. The Departments ofBotany and Genetics have a strong supporting group ofplant and molecular biologists and have excellent equip-ment, ample laboratory and growth chamber space and a50-acre field station with laboratory facilities. A tenure-track position would become available to the successfulcandidate. Initial appointment would be at the ASSIST-ANTPROFESSOR level (current salar range $40,035to $57,003, subject to negotiated adjustments). Theapplicant must have demonstrated research productivity,and will be expected to develop a program that willattract external funding and provide an environment forthe training of skilled personnel. She would be expectedto participate in teaching undergraduate and graduatecourses appropriate to her area of expertise.
In accordance with Canadian Immigration requirements,priority will be given to Canadian citizens and permanentresidents ofCanada. Interested applicants should apply bysending curriculum vitae, a statement of research inter-ests and the names of three referees by June 30, 1993, to:Chairman, Department of Genetics, University ofAlberta, Edmonton, Alberta, T6G 2E9, CANADA.
The University ofAlberta is committed to the principle ofequity in employment. The University encourages applica-tions from aboriginal persons, disabled persons, members ofvisible minorities and women.
ASSISTANT PROFESSORRENAL MATRIX GENE EXPRESSION
We seek a physician-scientist with at least 3 years ofresearch experience in molecular genetics of renal extra-cellular matrix components and their diseases to lead anindependent research program in this area. Applicationdeadline: July 15, 1993. Applications/3 academic refer-ences should be sent to: Dr. B. M. Brenner, Director,Renal Division, Brigham and Women's Hospital/Harvard Medical School, 75 Francis Street, Boston,MA 02115. Women and minorities are encouraged to apply.Affirmative Action/Equal Opportunity Employers.
RESEARCH ASSISTANT/ASSOCIATE PRO-FESSOR. Cognitive Neuropsychologist for MarylandPsychiatric Research Center Outpatient Program, Uni-versity of Maryland School of Medicine. Ph.D. Re-quired. Previous research experience in clinical neuro-science and schizophrenia required. This position will beresponsible for clinical care, administration and neuro-science research in an outpatient research unit. Sendcurriculum vitae to: Robert W. Buchanan, M.D.,Maryland Psychiatric Research Center, P.O. Box21247, Baltimore, MD 21228. Affirmative Action!Equal Opportunity Employer.
SCIENCE * VOL. 260 * 4 JUNE 1993
CONDITIONS: Personnel advertising isaccepted only with the understanding that theadvertisers do not discriminate amongapplicants on the basis of race, sex, religion,age, color, handicap or sexual preference.The AAAS encourages employers to activelyrecruit and employ underrepresentedminority groups. Science reserves the right,at its discretion, to decline to publishadvertisements submitted to it.
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POSITIONS OPEN
PHYSIOLOGIST ASSISTANT PROFESSORThe Department of Physiology invites applications
from individuals with at least 2 years of postdoctoralexperience for a tenure-track position. Cardiovascularresearch is emphasized but all qualified applicants will beconsidered. Successful candidate will establish an inde-pendent research program, seek extramural funding andparticipate in teaching medical physiology. Send curric-ulum vitae, brief description of teaching experience,current research activities, career goals, and names ofthree references to: D. Fred Peterson, Ph.D., Chair-man, Department ofPhysiology, Kirksville College ofOsteopathic Medicne (KCOM), Kirksvilie, MO
KCOM is an Equal Opportunity/Affirnmative ActionEmployer.
PSYCHOIMMUNOLOGY PH.D. RESEARCH-ER-ASSISTANT or ASSOCIATE PROFESSORlevel, with 2 to 5 years of previous academic erience.This individual will play a leadership role inte devel-opment of a psychoneuroimmunology laboratory toconduct human studies of the relationship between stressand depression with course of medical ifnon. The indi-vidual should be experienced in laboratory techniquesapplicable to human studies in psychoneuroimmunol-ogy, research design, and data analysis. Previous extra-mural funding is highly desirable. A competitive packageof laboratory start-up resources is available. Please con-tact: An Tasman, M.D., Professor and ChairmanDee~artment of Psychiatry and Behavioral Sciences,University of Luisville School of Medicine, Louis-ville, KY 40292; Telephone: (502) 588-1126.Affirm-ative Action/Equal Employment Opportunity.
Department of Psychiatry, University of Pennsylvaniahas position as RESEARCH ASSISTANT PROFES-SOR. Applicant should have background in cellular andmolecular biological approaches to the study ofactions ofdrugs. Salary support will be from research projects onmolecular biology of receptors in the human centralnervous system. A demonstrated ability to attract extra-mural support isessential. Applicants must have a Ph.D.with at least two years of postdoctoral trainin. Sendcurriculum vitae and names of referees to: Dr. Jeffrey N.Joyce, Laboratory of Chemical Neuroanatomy University of Pennsylvania School of Medicine, 422 Cu-Ae Boulevard, Philadelphia, PA 19104-6141. EqualOpportunity/Affirmative Action Employer.
VERTEBRATE ECOLOGY/BIOSTATISTICS.Tenure-track. ASSISTANT PROFESSOR. Possiblestarting date August 15, 1993. Teaching may includeAnatomy/Physiology, Ecology and Biostatistics. Re-search program will involve undergraduate and M.S.-level students. Submit letter of application, curriculumvitae, 3 letters of recommendation and transcripts byJune 30, 1993, to: Dr. V. L. Dunham, Head, Depart-ment of Biology, Western Kentucky University,Bowling Green, KY 42101-3576. Affirmative ActioniEqual Opportunity Employer. Women and minorities encour-aged to apply.
UTAH. The Department of Pediatrics, University ofUtah Health Sciences Center seeks an ASSISTANTPROFESSOR, board eligible/certified in both Pediat-rics and Child Psychiatry, to be a full-time member oftheDivision of General Pediatrics on the tenured or clinicaltrack with an adjunct appointment in the Department ofPsychiatry. The position is hospital-based through theUniversity of Utah Health Sciences Center and willinclude responsibilities in medical student and housestaffteaching, with an emphasis on behavior/development,consult-liaison at Primary Children's Medical Center andUniversity Medical Center. Inpatient and outpatientmanagement and clinical researc are expected. Closingdate is June 30, 1993. Please address inquiries to: ChuckNorlin, M.D., Chief, Division of General Pediatrics,University ofUtah Health Sciences Center, Salt LakeCity, UT 84132.An Equal Opportunity/Affirmative Action Employer and
encourages applicationsfrom women and minorities.
POSITIONS OPEN
DIRECTOR OF ANESTHESIA RESEARCHThe Department of Anesthesiology at The Ohio State
University is receiving applications for the position ofDirector of Anesthesia Research. This position demandsextensive experience in small animal surgery, researchdesign, initiation and supervision of ongoing researchprojects, and leadership in working with junior andsenior faculty. Applicants must have a Ph.D. Preferencewill be given to candidates with current nationally fund-ed research. Salary commensurate with experience andprofessorial position. Please send curriculum vitae to:John S. McDonald, M.D., Professor and Chairman,Department of Anesthesiology, The Ohio State Uni-versity, Room N437 Doan Hail, 410 West 10thAvenue, Columbus, OH 43210-1228. Telephone:(614) 293-8487.
UNIVERSITY OF THE VIRGIN ISLANDSST. THOMAS
ADMINISTRATIVE DIRECTORMARINE SCIENCE CENTER
Candidate should have a doctoral degree and academiccredentials and experience appropriate for appointmentat the Full Professor level. A strong successfu record ofinternationally recognized, externally funded research isrequired. Demonstrated experience with program devel-opment, management and familiarity with funding agen-cies and foundations are important. Knowledge of theCaribbean and tropical marine pence are desirable.The successful appointee will direct and expand themarine science program, seek extramural funding tofacilitate program expansion, increase Caribbean andinternational stature of the program and develop re-sources to support faculty research involving active un-dergraduate participation. The appointee will conductown research program and teach occasionally in area ofexpertise. The salary for this administrative positionranges from $43,742 to $60,549 for the administrativeyear. Applications accepted until July 1, 1993. A letter ofapplication, up-to-date resume, official transcripts andthree letters of recommendation should be addressed to:Dr. Denis Paul, Vice President for Academic Affairs,University of the Virgin Islands, Number 2 JohnBrewers Bay, Charlotte Amalic, VI 00802-9990.
Equal Opportunity/Affirmative ActionEmployer and Educator.
FACULTY CELL BIOLOGISTTenure-track, 12-month ASSISTANT PROFES-
SOR position available January 1, 1994, for an outstand-i animal cell biologist with expertise in cell regulation,cell signaling, or cell differentiation. Responsibilitiesinclude establishing an externally funded research pro-gram, teaching each year an undergraduate and an upper-level specialty course in cell or developmental biology,and advising undergraduate and graduate students.Ph.D. required and postdoctoral experience preferred.Submit (a) curriculum vitae, (b) 3 letters of recommen-dation, (c) up to 3 publications, (d) 1-page statement ofhow your research addresses important issues in cellbiology, and (e) 1-page summary of teaching philoso-phy, experience, and proposed courses. Send these itemsby August 15, 1993, to: R. Grossfeld, Cell BiologySearch Committee, Zoology Departnt, North Caro-lina State Universit, Raleig, NC 27695-7617.NCSU is anAffirmativeAction/Equal Opportunity Employerin the Research Triangle, a desirable environmentfor scholarlywork and year-round cultural and recreational activities.
FACULTY POSITIONASSISTANT PROFESSOR. The Division of Neu-
rosurgery, Louisiana State University School of Medi-cine in Shreveport, seeks applicants for a tenure-trackposition in Neurosurgery. Applicants must possess aPh.D. and will be expected to develop an independentresearch program. Expertise in molecular biology andimmunology is preferred. Affirmative Action/Equal Op-portunity Employer. Send curriculum vitae to: ANILNANDA, M.D., DIVISION OF NEUROSUR-GERY, P.O. BOX 33932, SHREVEPORT, LA71130.
POSITIONS OPEN
POSITIONS IN BIOLOGICAL SCIENCESThe Department of Biological Sciences, State Univer-
sity ofNew York College of-Optometry, seeks to fill twotenure-track positions at the ASSISTANT/ASSOCI-ATE PROFESSOR level. Candidates should eitherhave a Ph.D. in pharmacology or a closely related field, ora Ph.D. and an active research program in some of thefollowing areas: immunology, infectious diseases, molec-ular biology, ocular surface, pathology.
Responsibilities for the positions will include coursesin general and ocular pharmacology, and participation incourses in general andocular bioogy and microbiology.Both new faculty members will be expected to develop
independent research programs and participate in thetraining of O.D. and O.D./Ph.D. students, as well asresidents. Candidates should submit curriculum vitae andstatement of research interests and plans to: Harry J.Wyatt, Ph.D., Chair, Search Committee, Departmentof Biological Sciences, State University ofNew York,State College of Optonetry, 100 East 24th Street,New York, NY 10010. Telephone: 212/780-5163.Salaries and benefits competitive. An Equal Opportunity!Affirmative Action Employer.
FRESHWATER ECOLOGYThe Departement de sciences biologiques, Facult6 des
arts et des sciences of the Universit6 de Montrea, invitesapplications for a TENURE-TRACK POSiTION infundamental and applied freshwater ecology. Functions:the successfulcandidate will be expected to be able toteach courses in French at the undergraduate and grad-uate levels; to supervise graduate students; to carry outan active research program. Applications will be consid-ered based on merit and on their complementarity withthe research programs of the tquipe de recherche enecologie des eaux douces, which is a member of theGroupe de recherche interuniversitaire en limnologie(Gril). Among the important complementary fields aregeochemistry, biochemical ecology, molecular biology orgenetical ecology. Preference wil be given to candidateshaving interest and experience in global and regionalenvironmental changes in freshwater alga and plantcommunities, and those who would be able to use thefacilities of the Station de biologic des Laurentides.Requirements: candidates should have a Ph.D. in arelevant field, and postdoctoral or equivalent experience.Salary: based on current contract agreements. Appointment Date: the position begins 1 June 1994. Interestedapplicants should submit curriculum vitae, two copies offive representative reprints or preprints, and three lettersof reference before 31 August 1993 to: M. RaymondMcNeil, directeur, Departement de sciences bi-ologiques, Universite de Montrial, C.P. 6128, suc-cursale A, Montreal (Quebec), Canada, H3C 3J7. Inaccordance with Canadian Immigration requirements, prioritywill be given to Canadian citizens and landed immigrants.
The Department of Microbiology and Immunology,University of Maryland at Baltimore, is seeking appli-cants for a non-tenure-track position to DIRECT aMolecular Biology Core Facility. Applicants must have aPh.D. in Molecular Microbiology with a minimum of 4years of postdoctoral research experience and experiencedirecting personnel and Core Facility operations. Appli-cants must be experienced in DNA and peptide synthesis,automated fluorescence-based DNA sequencing, HPLCtechniques for purification of oligonucleotides, ptidesand proteins, and should have a broad knowledge ofcurrent techniques in Molecular Biology. The Director ofthis facility will also be expected to develop proposals forextramural funding for both laboratory equipment andpersonnel. Send curriculum vitae and three references to:Dr. Jan Cerny, Chairman, Department of Microbiol-ogy and Immunology, University of Maryland atBaltimore, Baltimore, MD 21201.The University of Maryland at Baltimore is an Equal
Opportunity Employer, M/F/H/V.
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ZENECA Pharmaceuticals Group (formerly ICIPharmaceuticals Group), dedicated to the challengeof discovering and developing important new
therapeutic agents, has openings in the CNS andPulmonary Pharmacology drug discovery researchgroups at our suburban Wilmington, Delawarelocation.
CNS PharmacologyThe successful candidates will participate in molecularbiological studies as part of an integrated team ofbiologists who interact closely with medicinal andmolecular modeling chemists. Both positions requireexpertise in construction/expression of vectors fortransient and stable mammalian cell expression andexperience with mutagenesis techniques. Expressioncloning of low abundance mRNA and genomic cloningis required.
SENIOR RESEARCH PHARMACOLOGIST-Weseeka Pharmacologist to participate in and supervisemolecular biological approaches, including cloningof drug therapy targets and their genetic manipula-tion. The successful candidate should have a PhD inmolecular biology, molecular genetics, pharmacol-ogy, or biochemistry, with at least 2 years' post-graduate experience. Broad knowledge and expe-
rience in PCR are required.
SENIOR PHARMACOLOGIST BS/MS in molecularbiology, molecular genetics, pharmacology, orbiochemistry, with at least2years' relevantexperiencein one or more areas of PCR is required.
Pulmonary PharmacologyRESEARCH PHARMACOLOGIST The successfulcandidate will interact in a team environment toestablish and biologically characterize chronic in vivomodels of pulmonary hypertension secondary tochronic obstructive pulmonary disease(s). A PhD inpulmonary physiology or pharmacology with 1-3years' postdoctoral experience in the area of pulmo-nary vascular smooth regulation is required. Back-ground in the principles of pharmacology alsorequired. Good communication skills and experiencewith in vitro and in vivo techniques are essential.Understanding of the fundamentals of computers isan asset.We offer competitive compensation, comprehensiveflexible benefits, a unique investment plan, and theopportunity to join a team of scientists from a broadrange of disciplines in an industrial pharmaceuticalresearch environment.Interested candidates should submit c.v. to: MelanieLewis, ZENECA Pharmaceuticals Group, 1800 Con-cord Pike, Wilmington, DE 19897.
ZENECAPharmaceuticals Group
ZENECA Pharmaceuticals/Stuart PharmaceuticalsBusiness Units of ZENECA Inc.
An Equal Opportunity Employer M/F.
1994 U.S. Public Health ServiceEpidemiology Gfaining
If you are interested in training and research in the field ofEpidemiology, now is the time to apply to the 1994 U.S. PublicHealth Service (PHS) Epidemiology Training Program (ETP).Acaos are currenly Iben acxed and are due onSet21, 1993. Traning will begin approximaelyJuly 1, 1994.
Program Features:For most trainees this is a three-year program. The firstyear, trainees may pursue an M.P.H. or equivalent byattending a university to study epidemiology, biostatistics,and related subjects. During the subsequent two years, theywill perform research with senior epidemiologist for one ofthe following agencies: National Institutes of Health (NIH),Food and Drug Administration (FDA), and the NationalCenter for Health Statistics (NCHS).Trainees are matched with a preceptor whose area of exper-tise is of interest and consistent with trainees' career plans.(In some cases, individuals accepted into the Program whohave already had a year of study in epidemiology and bio-statistics will be accepted for the final two years of theProgram.)Pay and allowances will depend on the personnel systemagreed upon by the preceptor and the trainee. Severaloptions are available depending on the agency selected.Agencies can use one of a number of mechanisms, the twomost common are:1. A limited appointment in the Commissioned Corps of theUnited States Public Health Service in which the usual start-ing rank for program entrants will be Lieutenant (0-3). Thestarting salary for an 0-3 medical officer with dependents isapproximately $43,460 depending on training and experi-ence. For non-medical officers of the same rank withdependents, the starting salary is approximately $38,460.Employment in the Commissioned Corps may allow for cer-tain tax exemptions. Candidates are asked to consult withtheir employing personnel office.2. Appointment as a staff fellow in the sponsoring agencywith starting salaries of approximately $38,500 for physi-cians and $28,000 for nonphysicians. An increase of up$2,000 per year will take effect in the second and third yearsof the program.Educational costs and allowable relocation expenses for thefirst year are provided. Trainees may also be eligible forhealth and life insurance benefits.Opportunities may be possible for physicians who join theETP to enroll simultaneously in a Preventive MedicineResidency Program leading toward board eligibility.
Basi Requinwument toApply:M.D., D.O., Doctorate in an allied health profession, orPh.D., in a biomedical or behavioral science or equivalent,and one year of postdoctoral training or experience by July1,1994;
U.S. citizenship as of September 21, 1993; and
Acceptability to an accredited university offering an M.P.H.or equivalent, or more advanced public health degree (forthe first year of the Program).
To obtain further Program details and an application pack-age, send a postcard with your printed name and homemailing address to: NIH Training Center, EpidemiologyTraining Program, EPS/100, 9000 Rockville Pike,Bethesda, MD 20892, or call 301/402-3402.Under the Affirmative Employment Program, minorities,women and persons with disabilities have been found to beunder-represented in the GS 601 and 602 Epidemiologistseries. Individuals who are members of these groups andmeet the eligibility criteria are encouraged to apply.
ThePMSE dmio T Pramis an Equal Oppority Empye. _1
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BIO -AAEGdeBoehringer IngelheimResearch Inc.
Bio-Mega/Boehringer Ingelheim Research Inc. is one of the leading pharmaceuticalresearch laboratories in Canada. We seek an experienced computational chemist to joinour research center located in the Montreal suburb of Laval.
COMPUTATIONAL CHEMIST
The successful candidate will work closely with medicinal chemists, biochemists andpharmacologists in the design and optimization of biologically active molecules. Thecandidate will also have the opportunity to interact with scientists working in the areas ofNMR and X-ray crystallography.The ideal candidate will possess a Ph.D. in organic chemistry or physical chemistry or arelated science. Experience in molecular modeling using molecular mechanics and/orquantum mechanical methods is essential. Preference will be given to candidates withexperience in modeling enzyme inhibitor interactions.Bio-Mega/Boehringer Ingelheim Research Inc. offers a competitive compensation andbenefits package in addition to the opportunity to work in a pleasant and intellectuallystimulating environment.Interested candidates should send their resume to:
Department of Human ResourcesBIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC.2100 Cunard St., Laval, Qc, Canada H7S 2G5FAX: (514) 682-8434
DHHS/PHS-The Food and Drug Administra-tion (FDA), Center for Biologic* Evaluationand Research (CBER), Division of BacterialProducts (DBP), invites applications for theposition of CHIEF, LABORATORY OF EN-TERIC AND SEXUALLY TRANSMITTED DIS-EASES, located In Bethesda, Maryland. TheLaboratory is responsible for conducting re-search and regulatory review related to en-teric and sexually transmitted infections.This is a supervisory interdisciplinary posi-tion appropriate for a physician, chemist,microbiologist, or biologist with post-gradu-ate training. The Laboratory Chief Is respon-sible for originating, developing, conductingand leading a research program related tothe biology of enteric and sexually transmit-ted bacteria. Demonstrated expertise in con-ducting research is required. Clinical andacademic opportunities are available. Salaryrange for chemist, microbiologist and biolo-gist Is $56,627 to $73,619 at the GM-14 leveland $66,609 to $86,589 at the GM-15 level.Salary range for physician is $66,067 to$83,059 at the GM-14 level and $71, 049 to$91,029 at the GM-15 level. Physicians mayalso be eligible for a Physician's Compara-bility Allowance up to $20,000 per year. Sal-ary is commensurate with education andexperience. The grade of the position de-pends upon the research qualifications ofthe candidate determined by the CBER PeerReview Board. Positions may be filled byappointment in the U.S. Public Heaith Ser-vice, Commissioned Corps, with commensu-rate salary and benefits. U.S. citizenship isrequired. FDA is an Equal Opportunity Em-ployer and has a smoke free environment.Send CV, three letters of recommendationand Standard Form 171 no later than July 30,1993 to: Maureen Waiter, Division of Bacteri-al Products, OVRR, CBER, FDA, HFM-425,Building 29, Room 224, 8600 Rockville Pike,Bethesda, Maryland 20892. For further infor-mation on application call Maureen Waiter at301-496-0395.
DEPARTMENT OF BIOLOGICAL SCIENCESAVIAN PHYSIOLOGICAL ECOLOGY
The Department of Biological Sciences invites applications for atenure track position. This is a re-advertisement, with the searchnow enlarged to consider applicants at the Associate as well as atthe Assistant level. We seek an ecologist with proven ability toundertake physiological research on free-living birds in an evolution-ary and ecological context. Possible areas of research includeenergetics, digestion or metabolism, but any relevant area may beconsidered. The successful applicant will hold an endowed positionfunded jointly by Simon Fraser University, the Canadian WildlifeService (CWS), and the Natural Sciences and Engineering Re-search Council (NSERC) of Canada, and will be part of a teamdevoted to basic research on the problems faced by birds inchanging environments. The candidate will be expected to teach inthe biology program and to interact with colleagues in the Depart-ment of Biological Sciences and the CWS.Interested applicants should send a letter outlining their researchinterests and how they fit the position's profile, a complete curricu-lum vitae, three letters of reference and three reprints to:
Dr. B.A. McKeown, ChairATT: Avian Physiological EcologistDepartment of Biological Sciences
Simon Fraser UniversityBumaby, B.C. Canada
V5A 1 S6CLOSING DATE FOR APPLICATIONS IS AUGUST 31, 1993Simon Fraser University is committed to the principle of equity inemployment and offers equal employment opportunities to qualifiedapplicants. The Department is particularly interested in increasingthe number of qualified female applicants. In accordance withCanadian immigration requirements, priority will be given to Cana-dian citizens and permanent residents of Canada.
NATIONAL INSTITUTE ON AGING
STAFF FELLOWSHIPON HUMAN MAGNETIC RESONANCESPECTROSCOPY AND IMAGING
Staff fellowships are available beginning July, 1993 forstudying human brain function in relation to aging andsuch disorders as Alzheimer's disease and multipleinfarct and other vascular dementias using in vivonuclear magnetic resonance spectroscopy and imagingtechniques. Data generated can be combined with thatobtained from positron emission tomography, neuropsy-chological testing, and neuropharmacological interven-tion. Responsibilities include writing and conductingresearch protocols, and limited clinical care on an 8-bedclinical research unit. MD degree and medical license(ECFMG if foreign trained) required. Fellows work in theLaboratory of Neurosciences (S.I. Rapoport, M.D.,Chief), Brain Aging and Dementia Section (M.B.Schapiro, M.D., Chief), National Institute on Aging,National Institutes of Health, Public Health Service,Bethesda, MD. Starting salary commensurate with train-ing and experience. For further information, contact:
Dr. B. Horwitz, Bldg. 10, Rm 6C-414Laboratory of NeurosciencesNational Institute on Aging
9000 Rockville Pike, Bethesda, MD 20892.Tel. 301-496-4754; FAX: 301-402-0595;
Email: [email protected] is an Equal Opportunity Employer
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PUBLIC HEALTH SERVICE * NATIONAL INSTITUTES OF HEALTH * NATIONAL INSTITUTE ON DRUG ABUSEPUBLIC HEALTH SERVICE * NATIONAL INSTITUTES OF HEALTH * NATIONAL INSTITUTE ON DRUG ABUSE
A Senior Executive Service Vacancy
Director, Division of Clinical ResearchLocation: Rockville, Maryland
The National Institute on Drug Abuse (NIDA) invites nominations and applications for this Senior Executive Service position,
located in Rockville, Maryland.
The Director, Division of Clinical Research (DCR), is responsible for the management and direction of the major Federal extra-
mural program of medical, applied, services and outcome research focusing on drug abuse treatment. The Director is respon-
sible for the planning, development and continuous enhancement of the Institute's grant and contract programs of clinicalresearch and research training. DCR has an FY 1993 budget of approximately $140 million and a staff of 45.
Desirable qualifications include an M.D. or Ph.D. degree with extensive postgraduate research experience, and experience inthe scientific and administrative management of research programs which has established the candidate as an authority in thefield of clinical research relevant to substance abuse.
The annual salary range for this position is $92,900 to $115,700. Physicians may be eligible for a Physician's ComparabilityAllowance of up to $20,000 per annum. A recruitment bonus of up to 25 percent of base pay may be available to a nonfederalcandidate selected for this position, subject to individual approval. A relocation bonus of up to 25 percent may be available to apermanent Federal employee who must relocate to accept this position, subject to individual approval. Submit applications(Application for Federal Employment, SF- 71), accompanied by a current curriculum vitae and bibliography to:
Ms. Nancy Egan 1x IN
Personnel Management Branch, NIDA5600 Fishers Lane, Room 10-21Rockville, Maryland 20857Phone 301/443-9593
Complete application material (which must include SF- 171) must be received by July 13, 1993.
NIDA IS AN EQUAL OPPORTUNITY EMPLOYER
Molecular Blosystems, Inc. (MBI), aworldleaderin the developmentof contrastagents for medical imaging, includingultrasound, MRIandCr hasanopportunityin our Analytical R&D bepartment for:
This position requires a BS in Chemistrwith 3 years lab experience or an MS with1 year lab experience in analytical chemis-try or pharmaceutical analysis.
Responsibilities include development &validation ofanalytical methods usingchro-matography (H1PLC, GC), spectroscopy (UN-VIS, FTIR, fluorescence, ICP), titrimetry &wet chemistry. Will also be involved in thetesting of bulk chemicals & formulateddosage forms. A working knowledge ofGLP compliance &computers is desirable.
MBI offers an excellent salary and benefitspackage, an opportunity to make a signifi-cant impact and an exceptional workingenvironment. Forimmediateconsideration,please send resume with salary history to:
Molecular Biosystems, Inc.HR Department, A19-94
10030 Barnes Can on RoadSan Diego, CA 92121
An Equal Opporiunity Employer
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POSITIONS OPEN
FACULTY POSITIONDEPARTMENT OF PHYSIOLOGYNEW YORK MEDICAL COLLEGE
Applications are invited for a tenure-track position inthe Department of Physiology. Candidates must have anindependent research program. Special consideration willbe gien to candidates with a background in molecularbio and/or cellular physiology and knowledge ofendotelial cell and vascular smooth muscle mechanisms.Faculty rank and salary will be commensurate withcredentials. Applicants should send curriculum vitae,history of past and current research funding, a statementof research interests and the names of 3 references to:
Gabor Kaley, Ph.D.Professor and ChairmanDepartment of PhysiologyNew York Medical College
Valhalla, NY 10595Equal Opportunity Employer, M/F/H/V.
HUXLEY COLLEGE OFENVIRONMENTAL STUDIES
WESTERN WASHINGTON UNIVERSITYTERRESTRIAL (FOREST) ECOLOGIST, Ph.D.
Huxley College of Environmental Studies is seekingoutstanding candidates for a tenure-track FACULTYPOSITION begini September 15, 1993. Experiencein teaching and current research in forest ecoloy atlandscape or regional scale is preferred. Teaching utiesinclude environmental systems, landscape ecology, con-servation biology, and graduate-level ecological methodswith a Northwest regional focus. Huxley College offersmultidisciplinary upper-division undergraduate andgraduate programs m environmental studies within acomprehensive university of about 10,000 students.Send cover letter, resume and names/addresses of threerefcrences to: Chair, Ecology Search Committee, Hux-ly College ofEnvironmental Studies, Western Wash-ingtonmerse iit MS 9180, Bellingham, WA
98-225. FAX: 2 50-2842. Email: [email protected]. Review of applications will beginJuly 1, 1993, and continue until the position is filled.
Western Washington University is committed to EqualOpportunity andAffirmativeAction. We are orking towardbuilding a culturally diverse, broadly trainedfaculty and staff:Women, minorities and persons with disabilities are encour-aged to apply. Persons with disabilities needing assistancein the application process may call (206) 650-3306. Forthe heanng impaired, call the Washington State TDDRelay Service (WSTRS) 1-800-833-6388.
PLANT SYSTEMATIST-MONOGRAPHER
The Rancho Santa Ana Botanic Garden Program inBotany invites applications for a FACULTY POSI-TION to begin January 1994. We seek a Ph.D-levelresearcher who conducts modem monographic research.Preference will be given to applicants working on vascu-lar plants. Applications at al academic levels will beaccepted. The successful candidate will be expected toestablish and maintain a vigorous research program andto ply an active role in the graduate program. For fullconsideration, applicants should send curriculum vitaeand statement of research interests, and have three lettersof reference sent to: Dr. Thomas S. Elias, Director,Rancho Santa Ana Botanic Garden, 1500 NorthCollege Avenue, Claremont, CA 91711 by 15 August1993. The Rancho Santa Ana Botanic Garden is an EqualOpportunity/4lfirmative Action Employer and encouragesapplications from members of minority groups and women.
SENIOR POSTDOCTORAL POSITIONAvailable in NIH- and OCAST-funded laboratory to
study the molecular mechanisms ofdrug resistance in theHIV virus. The applicant should have a strong back-ground in computational and theoretical chemistry. Pre-vious experience in the study of electrostatic interactionsin proteins is advantageous. The initial apointment isfor a 2-year period starting July 1993. Sary commen-surate with experience. Send cover letter, curriculumvitae, background description and the names of tworeferences to: Dr. Fredy Susman, Unvrsity of Okla-homa Health Sciences Center, 801 N.E. 13th Street,Oklahoma City, OK 73190.
POSITIONS OPEN
POSTDOCTORAL POSITION available immedi-ately to conduct electrophysiological and pharmacologi-cal studies of the inositol phosphate cascade in photore-ceptors. Please submit curriculum vitae and three lettersof recommendation to:
Alan Fein, Ph.D.Department of Physiology MC3505
University of Connecticut Health CenterFarmington CT 06030
An Affirmative Action/Equal Opportunity Employer,M/F/D/V.
POSTDOCTORAL POSITION available immedi-ately to study the molecular basis of hematologicaltoxicity induced by anti-HIV drugs. Experience in labo-ratory techniques of cell culture and molecular biology isrequired. Send curriculum vitae and names of threereferences to: Dr. Krishna C. Agrawal, Department ofPharmacology, Tulane University School of Medi-cne, New Orleans, LA 70112. Tulane is an EqualOpportunity/Affirmative Action Employer.
POSTDOCTORAL RESEARCH-Two projectsavailable at Tyndall Air Force Base in Panama City,Florida, for recent (last 3 years preferred) doctoral degreerecipients in biochemistry, microbiology, or related dis-cipline. One project involves bacterial degradation oforganic pollutants in groundwater. The other involvesisolation and characterixation of redox proteins in sedi-ments and plant material. Contact: Postgraduate Re-search Program/TAFB, Science/E eering Edca-tion Division, Oak Ridge Institute for Scnce andEducation, P.O. Box 117, Oak Ridge, TN 37831-0117, Telephone: (615) 576-3456.
POSTDOCTORAL POSMONMOLECULAR VIROLOGY
Immediate opening to study the molecular biology ofsatellite RNA-mediated disease attenuation in virus in-fected plants with emphasis on satellite RNA bindingproteins. A Ph.D. in Virology, Molecular Biology, orrelated field required. Send rnsume and three letters ofreference to: Dr. S. A. Ghabrial, Plant PathologDepartment, University of Kentucky, Lxxington, I40546. An Equal Opportunity Employer.
POSTDOCTORAL POSiTIONSThe Dana-Farber Cancer Institute seeks to fill research
positions at the postdoctoral level to study the molecularmechanisms of the development and function of T-cellsubsets. Applicants should have a background in cellularimmunology and/or molecular biology. Joint appoint-ment to be held in an appropriate department ofHarvardMedical School. Send curriculum vitae and 3 referencesto:
Dr. Harvey CantorLaboratory of ImmunopathologyDana-Farber Cancer Institute
44 Binney Street, Boston, MA 02115 USA
Two POSTDOCTORAL POSMONS are availableimmediately on an NIH Institutional Training Grant inthe area of diabetes and hormone action; regulation ofinsulin secretion in pancreatic beta cells; molecular mech-anisms of receptor-based signal transduction pathways.Applicants should have an M.D. or Ph.D. degree and bea U.S. citizen orpermanent resident. Minority applicants areencouraged. Send curriculum vitae and names of threereferences to: Dr. John R. Williamson, Deament ofBiochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104. FAX: 215-898-9918.Equal Opportunity Employer.
POSTDOCTORAL POSMONS available for re-cent Ph.D. with training in biochemistry, enzymology,biomedical engineering, or other related biochemicalareas to work on research projects involving drug remov-al and delivery. Experience or knowledge in enzymemodification, blood coagulation, thrombolysis, immu-nology, and animal work are desirable. Ability to workacross disciplines essential. Send resume and three lettersof reference to: Dr. Victor C. Yang, College of Phar-macy, The University of Michigan, Ann Arbor, MI48109-1065. The University ofMichigan is an Affirma-tive Action/Equal Opportunity Employer.
POSITIONS OPEN
POSTDOCTORAL RESEARCH SCIENTIST/STAFF ASSOCIATE
Available immediately to study genetic control oftumor proeion in intracranial tumors and tumor-derived cell lines. Projects focus on genomic instability,genetic control of tumor cell invasion, and adenovirusinteractions in the brain cells. Expertise in cell culture,gene expression analysis, basic molecular biology, andvirology is required. Applicants must be highly motivat-ed. Send curniculum vitae and names of three referencesto: Gregory J. Ph.D., Deprment ofNeuro-surgery, NI-Unit 147, Columbia University, Coliegeof Physicians & Surgons, 710 West 168th Street,New York, NY 10032. Affirmative Action/Equal Oppor-tunity Employer.
POSTDOCTORAL POSITIONSIN YEAST MOLECULAR GENETICS
Two positions are available to study mechanisms oftranscriptional regulation. Projects consist of definingand characterixing:* components of the general transcriptional apparatus* components of the heat shock response pathwayExperience in molecular biology is essential. Send
curriculum vitae and the names of three references to:Dr. David S. Gross or Dr. Michael Hampsey, Depart-ment of Biochemistry and Molecular Biology, Loui-siana State University Medical Center, 1501 KingsHighway, Shreveport, LA 71130-3932. LSUMC isan Equal Opportunity/Affirmative Action Employer.
RESEARCH ASSOCIATE POSITION to managethe automated DNA sequencing section of the W. M.Keck Facility Biotechnology Resource Laboratory atYale University. Applicants should have a Ph.D. inbiochemistry or a related science and extensive experiencewith DNA sequencing and molecular biology tech-niques. Candidates should also have good interpersonaland communication skills. Opportunities will be provid-ed for independent research that ma focus on improvingDNA sequencing methodolo, on human genome marping or sequencing or on other topics that are comple-mentary to research that is ongoing within the laboratoryof IL Williams on understanding structure/functionrelationships in single-stranded nucleic acid binding proteins. The successful applicant will be encouraged topursue independent grant support as well as to assist inthe preparation of shared instrumentation grant propos-als. The position will be available this summer and thesalary willbe commensurate with the level of experience.Curriculum vitae should be sent to: Ken Williams,Ph.D., W. M. Keck Foundation Biotechnology Re-source Laboratory, Boyer Center for Molecular Med-icine, 295 Congress Avenue, New Haven, CT 06536-0812. Yale University is an Equal Opportunity Employer.
RESEARCH ASSOCIATEWestern Psychiatric Institute and Clinic/University of
Pittsburgh Medical Center currently seeks qualified ap-plicants for the position of Research Associate in itsPittsburgh Adolescent Research Center.The incumbent will be responsible for collecting serum
samples; using a sep-pac extraction to isolate caffeine/antipynn; using high performance liquid chromatogra-phy for the determination of caffeine levels as well as theuse of gas chromatography/mass spectrometry. In addi-tion, the incumbent will run electrophoresis and Brad-ford protein determination assays. Will also be responsi-ble for database management using DataEase and Quot-tro to generate linear regression analysis of data.The successful candidate must have a Bachelores degree
in a Biological Science with a minimum of five years ofexperience with HPLC, gas chromatography/mass spec-trometry and the ability to use data management pro-grams incuding DataEase and Quotrro. Candidateshould be familiar with ultraviolet, electrochemical andreactive index detection by HPLC andUV spectrometry.Basic knowledge of statistics is necessary.The starting salary for this position is $19,843. We
offer a competitive fringe benefit program including a
tuition assistance program. Interested candidates sendrisumes and salary history to: Andrea Hedegus, Ph.D.,WESTERN PSYCHIATRIC INSTITUTE ANDCLIIC/UPMC, 3811 O'Hara Street, Pittsburgh,PA 15213. An Equal Opportunity Employer.
SCIENCE * VOL. 260 * 4 JUNE 19931542
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Mitotix, Inc., a well-funded newbiopharmaceutical company, is devel-oping cell-cycle based therapeuticsfor cancer and infectious diseases.
We are looking for creative, highlymotivated and enthusiastic Post-Doctoral Scientists with a strongrecord of achievement in either theacademic or industrial environment.
Cell geneticists, with experience inexpression cloning, cDNA libraryconstruction, genetic manipulation ofyeast or mammalian cells.
Protein biochemists, with experi-ence in protein purification and char-acterization and/or peptide chemistry.
Structural biologists, with experi-ence in macromolecular computermodeling and/or protein structuredetermination by physicochemicalmethods.
Two-year Fellowships will beawarded, with the possibility of athird year, based on performance.We offer competitive salaries andbenefits, a wonderful location in theheart of Cambridge's scientific com-munity, and the chance to work withleading science and business pro-
fessionals. We are strongly commit-ted to research and encourageparticipation in scientific meetingsand publication of scientific results.
Send a curriculum vitae and thenames and addresses of three refer-ences to: Giulio Draetta, VicePresident for Biological Research,Mitotix, Inc., One Kendall Square,Building 600, Cambridge, MA 02139,USA. An Equal Opportunity Employer.
Mitotix
Naffonc Cancer hsflMeNatlnd Etnesof Hedlh, Pibic Headlh Service
The Division of Cancer Prevention and Control(DCPC) is accepting applications for the CancerPrevention Felbwsip Program (CPFP). The purposeof this program is to train indiduals from a multiplicityof health science dsipAlnes in the field ofcar pre-vention and control. The program provides for:Master of Public Health training (at accredited univer-sity programs); Participation in the DCPC CancerPrevention and Control Academic Summer Course(open to all physicians and scientists interested inlearning the principles and practice of cancer pre-vention and control); Working at NO directly with in*dvidual preceptors on cancer prevention and controlprojects; Reld assignments in cancer prevention andcontrol programs at other instituton. Funding permit-ting, as many as ten Felows win be accepted for upto three years of training, beginning July 1, 1994.Benefits include selected relocation and travelexpenses, paid federal holidays, and participatoryhealth insurance.
M.D., D.D.S., D.O. from a U.S., terrttorial, or CanadianMedical School. Foreign medical graduates musthave current ECFMG/FMGEMS certification andappropriate expeience, e.g., one year residency ina training program approved by the AccreditationCouncil for Graduate Medicai Education.
Ph.D., Dr.P.H. or other doctoral degree in a relateddiscipline (epidemiology, biostatistics, and the bio-medical, nutritional, public health or behavioral sci-ences). Foreign education must be comparable tothat received in accredited U.S., territorial, orCanadian institons.
U.S. citizenshp or resident alien eligbe for citienshipwithin four years.For details and application catalog send a postcardor letter with your name and home address to:Douglas L. Weed, M.D., M.P.H., Ph.D.DirectorCancer Prevention Fellowship ProgramDivision of Cancer Preventionand ControlNational Cancer InstituteExecutive Plaza South, T-41Bethesda, MD 20892***Furherqk : Mrs. Babaa Redcing,(301)4968640DEADUNE FOR RECEIPT OF APPLCAllONT: SEPTEMBER 1,1993
NH sanEqucOpportuniy Emplye
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NATIONAL UNIVERSITYOF SINGAPORE
5/ DEPARTMENT OFORTHOPAEDIC SURGERY
Applications are invited for teaching appointments in theDepartment of Orthopaedic Surgery.Candidates applying foran appointment as Lecturer shouldpossess registrable medical degree together with relevanthigher professionaVacademic qualifications.For short-term appointments as Fellow/Senior Fellow, thecontract will be for one year in the first instance, with thepossibility of further extension. Appointees will carry outresearch in one of the following areas and be expected toparticipate actively in the teaching of undergraduates andclinical activities of the Department:
SpinePaediatric OrthopaedicsOrthopsedic Research
Adult Reconstructive SurgeryLaboratory facilities are available for animal surgery, motionanalysis, biomechanics, histology and biochemistry relatedto orthopaedic research.The commencing salary will depend upon the candidate'squalificatins experience and the intment offered.Gross annual emoluments range as fol ws:
Lecturer/Fellow S$53,160 - 64,200Senior Fellow S$58,680 - 100,310
(US$1.00 - S$1.60 approximately)In addition, the Professional Fee Scheme will apply toappointments who are accorded clinical appointments bythe National University Hospital.Leave and medical benefits will be provided. Depending onthe type of contract offered, other benefits may include:provident fund benefits or an end-of-contract gratuity, asettling-in allowance of S$1,000 or S$2,000, subsidisedhousing or a housing allowance, education allowance for upto three children subject to a maximum of S$116,425 perannum per child, passage assistance and baggage allow-ance forthe transportation of personal effects to Singapore.
All academic staff have access to the following computerand telecommunication resources: a networked microcom-puter (an IBM compatible or Apple Macintosh); an IBMmainframe computer with 16 MIPS of computing power; anNEC SX supercomputer with 650 MFLOPS of computingpower; departmental laser printers; a wide spectrum ofmainframe and microcomputer software; voice-mail. Thecampus-wide network, which is based on the high speedoptical fibre based FDDI technology, links up allthe aca-demic staff and student microcomputers, UNIX worksta-tions and provides access to the mainframe computer, thesupercomputer, UNIX hosts, the on-line library catalogue,CD-ROM databases, Teleview, Intemet and BIThET.
Application forms and further information on terms andconditions of service may be obtained from:
The DirectorPersonnel DepartmentNadonal Universityof Singapore
10 Kent Ridge CrescentSingapore 0511
The DirectorNorth Ameice 0iNational Universityof Singapore
55 East 59th StreetNew York, NW. 10022, U.S.A.Tel: (212) 7510331
Enquiries may alsobesentthrough BITNETto:PERUMMJ@NUS3O9O, or through Telfax: (65) 7783948.
National Institutes of Health * National Institute ofGeneral Medical SciencesMinority Opportunities in Research Programs Branch
Director, Minority Opportunities inResearch Programs Branch
This is a civil service position in the Senior Executive Service (SES)with a salary range from $92,900 to $107,300.Serves as the principal advisor to the Director, NIGMS, regarding theoverall direction of and approaches to the Institute's minority researchand research training programs. Advises NIGMS senior staff and, asappropriate, officials of other NIH ICDs, of NIH as a whole, or of otheragencies, as well as members of Congress, on trends and developmentsconcerning these programs as they relate to the missions of theNIGMS, NIH, PHS, DHHS, other Federal agencies, the biomedicalresearch community, and related groups. Keeps the Director, NIGMS,and other officials fully informed of program and related considera-tions having significant bearing upon the planning, development, andadministration of NIGMS minority research and research training pro-grams. Oversees resource allocations and advises the Director,NIGMS, as to distribution among the various minority research andresearch training mechanisms supported by the Institute as well aspriorities in regard to award of specific grants. Serves as a channel ofcommunication with the NIH, other agencies, the Congress, and theextramural community regarding these programs.Position information and qualifications requirements may be obtainedby contacting:
Howard R. Chernoff, Personnel OfficerNational Institute of General Medical Sciences
5333 Westbard Avenue, Room 803, Bethesda, MD 20892(301) 594-7767
Application for Federal Employment (SF-171), CV and Bibliography mustbe submitted to above address and received no later than July 1, 1993.
Selection for this pesiston will be based oolely on merit, with no ismination for non-merit reason such asracm, color, religion, son national o politics, marital statun, physical or mental handicap, age, or member-ship or non-membership in an employee org tionL
NIH is an Equal Opportunity Employer
The NumbersSpeak for Themselves.
Look at the audited paid circulationof these two publications:
154,842 Science*51,306 Nature**
SCIENCE, the global weekly of research.
For more information, contact:Janis Crowley, 212-496-7704 (U.S.)
In Europe, contactAnnemarie Vis, +44 223 302 067
* December 1992 ABC Publisher's Statement** December 1992 BPA Publisher's Statement
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SCHOOL OF MEDICINEC.R. ROPER FELLOWSHIP FOR THE
PROMOTION OF MEDICAL RESEARCHApplications are invited for appointment as the C.R.
Roper Fellow for research in either clinical or non-clinicalareas.
You will possess suitable qualifications in an appropriateand acceptable research field. You should consult with theHead of the appropriate department with in the Faculty ofMedicine, Dentistry and Health Sciences concerning theacceptability of your research project. Evidence of thedepartment's acceptance must be included with theapplication. It is anticipated that the appointment will bemade in 1993, for two years, and thereafter by negotiation.
Salary: $41,000-$48,688 p.a. (Research Fellow Gr 2);$50,225-$57,913 (Senior Research Fellow). A grant-in-aid ofup to $4,100 per annum may also be available.
For further information and a position description,phone the Administrative Officer, School of Medicine, on(03) 344 4019; or fax (03) 344 5998.
Applications close: 23 July 1993.Reference number: B500A911Applications should be sent, in duplicate, quoting three
referees (including facsimile numbers) to the Director,Personnel Services, The University of Melbourne, Parkville,Victoria, 3052.
THE UNIVERSITY OF MELBOURNE AND THECRC FOR INDUSTRIAL PLANT POLYMERS
SENIOR RESEARCH FELLOWThe Centre for Industrial Plant Biopolymers is a co-
operative venture involving The University of Melbourne(Department of Chemical Engineering/School of Botany),CSIRO Division of Food Science and Technology, and acommercial partner Tridan-Bunge Ltd.
The Research and Development Programme is focussedon evaluating the potential of plant cells in culture as asource of plant gums for commercial use. One aspect ofthis programme is to understand the molecular structureand physico-chemistry of the gum components, theirphysical interactions and functional properties.
You would be expected to initiate and co-ordinate abasic and strategic research programme to examine thefunctional properties of these gums and the relationshipbetween structure and function, under the direction ofProfessor D V Boger.
You must have experience in physico-chemical techniquesand their application in polymer systems. Experience in thefield of chemical engineering and/or complex carbohydrateswould also be an advantage. A capacity to interact withmulti-disciplinary research groups and industry is a primaryrequirement.
The position is for three years in the first instance, withan option of a further two years.
Salary: $50,225-$57,913 p.a. (Senior Research Fellow);$60,475-$66,625 p.a. (Principal Research Fellow)
For further information and a position description,phone Professor D V Boger on (613) 344 7440, Dr A Bacicon (613) 344 5041 or Dr D Hawley on (613) 344 5043; or fax(613) 347 1071.
Applications close: 18 June 1993Reference number: G/411/170Applications should be sent, in duplicate, quoting six
referees (including facsimile numbers) to the Director,Personnel Services, The University of Melbourne, Parkville,Victoria, 3052.
The University of Melbourne is an equal opportunity employerand has a smoke-free workplace policy.
THE UNIVERSITY OF MELBOURNE.M ORE TH A N A D EG RE E
UMC 16198 Thomson White/FCB
- I.I.U. RUIITIE U II IJ.[U I DI.M U RI I.
give us your best.......
or more than 115 years, scientists at EliLilly and Company have been developing novel,high quality pharmaceutical products. With acurrent yearly investment of over $900 million inresearch and development programs, our contin-ued success in reducing the time required to getnew drug candidates to market requires thefinest scientific talent available.
To further build our research capabilities,we are seeking self-motivated, innovative BS, MSand PhD level scientists to plan, organize, andmanage programs in the area of pre-clinical andclinical drug metabolism.
Successful PhD candidateswoil establisha laboratory program utilizing basic and appliedapproaches to study the metabolism and disposi-tion of drug candidates. Applicants must have aPhD degree in biochemistry, analytical chemistry,medicinal chemistry, bioanalytical chemistry, or arelated field; and experience in HPLC and otherquantitative analytical methods to study absorption,distribution, metabolism, and excretion of drugs inanimal models and humans. A strong background inpharmacologic and pharmacokinetic mechanisms asthey relate to drug disposition is desirable.
Successful BS and MS scientists areneeded to work collaboratively with senior investi-gators to study chemical transformations in biolog-ical systems. Ideal candidates will have a BS orMS degree in analytical chemistry, biochemistry,or in a related discipline; experience in developingand implementing quantitative bioanalyticalmethods using HPLC and/or Go systems; and ex-cellent organizational and communication skills.Experience with computer data systems and radio-chemicals is desirable.
Eli Lilly and Company offers a competitivecompensation and benefits package and a highlyprofessional environment. For prompt consideration,please forward your resume to: Eli Lilly andCompany, Scientific Recruitment, Dept. DMDS,Llly Corporate Center, Indianapolis, IN 46285.
We are an equal opportunity employer com-mitted to diversity in the workplace.
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POSITIONS OPEN
POSTDOCTORAL POSITIONS available to studymolecular mechanisms of mitochondrial biogenesis inS. cerevisiae. Projects include (1) studies of in vitrosplicing of mitochondrial RNA or (2) studies of func-tions of the PET117 and PET191 gene products incytochrome oxidase assembly. Salary is $27,700 per year.Send curriculum vitae and names of 3 references to: Dr.Joan E. McEwen, Department ofMolecular Genetics,Beckman Research situte, City of Hope MedicalCenter, 1450 East Duarte Duarte, CA 91010.An Equal Opportunity Employer; Email: [email protected].
POSTDOCTORAL POSITION available immedi-ately for a recent Ph.D. with a strong background inprotein chemistry to study the biochemistry of plasmin-ogen activators and their roles in fibrinolysis, angiogen-esis and tumor migration. Send curriculum vitae andnames of three references to: Dr. J. Liu, VascularResearch Lab, Deaconess Hospital, Harvard MedicalSchool, 185 Pilgrim Road, Boston, MA 02215.(Email address is [email protected]). The Dea-coness Hospital is an Equal Opportunity/Afflrmative ActionEmployer.
MOLECULAR BIOLOGY OF AGING:PRE- AND POSTDOCTORAL POSITIONSNIH-supported predoctoral position currently is avail-
able to study the molecular biology of aging in theDepartment of Cellular and Structural Biology at theUniversity of Texas Health Science Center at San Anto-nio. A postdoctoral position will be available as ofJanuary 1994. Research interests of the participatingfaculty range from characterization of transacting pro-teins to gene regulation in tranagenic mice. Interestedindividuals should write to: Barbara H. Bowman,Ph.D., Professor and Chair, Department of Cellularand Structural Biology, The University of TexasHealth Science Center at San Antonio, 7703 FloydCurl Drive, San Antonio, TX 78284-7762. TrainingFaculty: G.S. Adrian, B.H. Bowman, I.L. Cameron,B. Chatterjee, J.M Dubinsky, P. Jagadeeswaran, Rj.Klebe, E.B. Kraig, Rj. Leach, E.Y.H.P. Lee, W.H.Lee, W.W. Morga S.L. Naylor, J.F. Nelson, Rj.Reiter, AKG. Richardson, A.KL Roy, AKY. Saaguchi,C.A. Walter, and F. Yang. The University of TexasHealth Science Center at San Antonio is an Equal Employ-ment Opportunity/A~ffirmative Action Employer.
POSTDOCTORAL FELLOW-The DepartmentofMedical Cell Biology at the Alfred I. duPont Instituteseeks a postdoctoral fellow to participate in an NIH-funded research project on mechanisms of amino acidand iron nutrition in the mammalian embryo. Candidatesshould possess a Ph.D. and relevant experience in cellbiology or a related field. Send inquiries to: Department#8801, Attention: Dr. J. B. Lloyd, Director, Depart-ment of Medical Cell Biology, ALFRED I. duPONTINSITUTE, P.O. Box 269, Wilmington, DE19899. Equal Opportunity Employer.
POSTDOCTORAL/GRADUATE FELLOW-SHIPS in spinal trauma research. Two Predoctoralfellowships immediately available. Strong biology back-ground required. Postdoctoral work requires experiencein "evoked potential" recording to be used in clinicalwork with canines. Graduate candidates must be U.S.Citizen/National. Send curriculum vitae/references to:Dr. RB. Borgens, Center for Paralysis Research,School of Veterinary Medicine, Purdue University,West Lafayette, IN 47907. Affirmative Action/EqualOpportunity Employer.
POSTDOCTORAL FELLOWTo work with multidisciplinary group on generation
of new tissue equivalents using cultured cells on novelpolymer scaffolds. Focus will be on hepatocytes andcontrol of hepatocyte function through matrix interac-tion. Available immediately. Send curriculum vitae, state-ment of research interests, and names and addresses ofthree references to: Joseph P. Vacanti, M.D., Depart-ment of Surgical Research, Children's Hospital, 300Longwood Avenue, Boston, MA 02115. Children'sHospital is an Equal Opportunity Employer.
POSITIONS OPEN
POSTDOCTORAL SENIOR RESEARCH AS-SOCIATE position in collagen pathobiology or bio-chemistry available immediately. Opportunity to studytendon and ligament repair processes. The successfulcandidate will supervise lab staff. Send curriculum vitaeand references to: Chukuka S. Enwemeka, Ph.D.,Professor and Chairman, Department of PhysicalTherapy Education, University of Kansas MedicalCenter, 3901 Rainbow Boulevard, Kansas City, KS66160-7601.
APPLIED ECOLOGIST:3D/Environmental Services, Inc., a rapidly growing,
multidisciplinary consulting firm seeks to hire an appliedecologist with a graduate degree and a minimum of 3years ofexperience. Experience should emphasize impactassessment, habitat restoration/creation, and projectmanagement. A strength in vertebrate community ecol-ogy is strongly desired. Experience with endangeredspecies management and multidisciplinary projects isdesirable. Strong written and oral skills and analyticability are essential. Send application materials to: Dr.Virpil Brack, Jr., 3D/ESI, 781 Neeb Road, Cincin-nati, OH 45233.
FLOW CYTOMETRY TECHNOLOGISTApplicants should possess a minimum of 3 to 6 years
of flow cytometry laboratory experience in a basic re-search environment. In addition to extensive hands-onexperience with the day-to-day operation of a research-grade flow cytometer, the successful candidate shouldhave a comprehensive background in specimen prepara-tion protocols, new methods development and valida-tion, implementation of novel techniques, and instru-ment troubleshooting and end-user maintenance proce-dures. Data reduction, statistical analysis, and graphicalpresentation of analyzed data as well as technical writingskills are a component of the position. Previous experi-ence with Coulter flow cytometry instrumentation andthe isolation and functional assessment ofimmune cells ishighly desirable.
Interested applicants should submit current reisum6, alist of references, and salary history indicating POSI-TION #93-K21-H to: KRUG Life Sciences, Inc.,Human Resources Department, P.O. Box 58827,Houston, TX 77258-8827. Employment Eligibility Ver-fication Required. Equal Opportunity Employer, M/F/H/V. Smoke-free workplace.
SUPERVISOR/ELECTRON MICROSCOPYSupervise and perform day-to-day operations of the
Electron Microscopy Facility and assist investigators.Bachelor's degree including course work in biological
andlor physical sciences and at least 2 years of experiencein EM, or master's degree and at least 1 year of relevantexperience.
Qualifications include comprehensive knowledge ofEM and ability to establish harmonious relations.
Qualified applicants should send a resume and namesof references to: Dr. W.B. Rhoten, Department ofAnatomy and Cell Biology, School ofMedicine, Mar-shall University, Huntington, WV 25755-9350.
For full consideration submit application by June 30,1993.MARSHALL UNIVERSITY IS AN AFFIRMA-
TIVE ACTION/EQUAL OPPORTUNITY EM-PLOYER. WOMEN AND MINORITIES ARE EN-COURAGED TOAPPLY
RESEARCH SCIENTISTPosition is immediately available to study the struc-
ture-function relationship of IL-1 receptors type I andtype II. Specific requirements include strong backgroundin molecular biology, including cDNA cloning and se-quencing, vector construction, point mutations andPCR. Send resume, names and addresses of three refer-ences and salary requirements to:
David Benjamin, M.D.1232 James Cancer Hospital and Research Institute
The Ohio State University Hospitals300 West 10th Avenue
Columbus, OH 43210-1228Telephone: (614) 293-3716, FAX: (614) 293-3112
POSITIONS OPEN
INTERNATIONAL FELLOWSHIPThe Dan Charitable Trust Fund for Research in Bio-
logical Sciences provides financial support for collabora-tive research between Japan and other countries orparticipation in international conferences or workshopsheld in Japan or other countries. A total of6 fellowships(1- or 3-month duration) will be awarded every year.Applications for fellowships must be submitted to theaddress listed below by Oober 31,1993. For moreinformation, write: Kiyo Yamauchi, The Dan Charita-ble Trast Fund for Research in the Biological Sci-ences, Nippon Trust Bank, 3-1-8 Nihonbashi,Chuoku, Tokyo 103, Japan. FAX: (03) 3271-2843.
MOLECULAR BIOLOGISTS. Two positionsavailable (Ph.D. and M.S.) for individuals with an inter-est in applying molecular biology to unique problems inbotanically related biosyntheses. Experience with (1)expression of heterologous proteins in E. coli or yeast,(2) bioactive compounds derived from plants, and/or (3)organic chemistry is a plus. Ability to work as part of ateam is a must. The project is NIST-funded to developpyrethrins through a marriage of molecular biology andchemistry.AgriDyne is a biotechnology company dedicated to
the development of environmentally compatible cropprotection products. Our current products are effica-cious, biorational azadirachtin-based insecticides. We arelocated by the Wasatch Mountains in Salt Lake City withnumerous recreational opportunities. Salaries will becommensurate with experience and qualifications. Sendcurriculum vitae, summary of research experience, andnames of three references to: Ms. Teri Featherstone,Personnel, Agrilyne Technologies Inc., 417 WakaraWay, Salt Lae City, UT 84108.
NEUROGERONTOLOGY INSITIUTIONALPHYSICIAN/SCIENTIST PROGRAM
The University of Southern California has recentlyreceived an award from the National Institute on Agingfor a Physician/Scientist Program for the development ofbasic and clinical research skills for the study of diseasesrelated to the aging nervous system. This is a five-yearsalary award with appointments in the Department ofNeurology of the school of Medicine and in the Schoolof Gerontology. Candidate must be a U.S. Citizen or havepermanent U.S. Resident status and be board eligible inneurology, psychiatry, neuropathology, or internal med-icine. The first two to three years are spent in basicresearch at the Andrus Gerontology Center or the HedcoNeuroscience Neural Information and Behavioral Sci-ence Program. During the third year, the candidate joinsthe Department of Neurology as Assistant Professor(tenure-track). He or she continues clinical training inneurogerontology and develops individual research pro-gram. Clinical responsibilities are limited to 25% of timeand include teaching students, residents, and fellows inneurogerontology.
This position is open immediately. To apply sendcurriculum vitae and three letters of recommendation to:Leslie P. Weiner, M.D., Department of Neurology,USC School ofMedicine, 1510 San Pablo Street, LosAngeles, CA 90033-4606, and arrange for two days ofinterviews. For further information, call: 213/342-5793.
PRODUCT DEVELOPMENT SCIENTISTGenetic Testing Institute (GTI), a company engaged
in the manufacture and distribution of immunodiagnos-tic reagents and kits, is seeking a scientist to help conceiveand develop new products. Preference will be given tocandidates with background in immunology and experi-ence in molecular genetics. The successful candidate willhave the opportunity for a close interaction with anacademic research institute having a worldwide reputa-tion. Ph.D. degree and a minimum of two years ofpostdoctoral experience required. Curriculum vitae andrelevant background information should be sent to:
Jim Tidey, PresidentGTI
150 North Patrick BoulevardBrookficld, WI 53045
GTI is an AffimatvectioEa Opptunity Employer.
SCIENCE * VOL. 260 * 4 JUNE 19931546
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ANNOUNCEMENT
PENNSTATE
Nominations and Applications are Invited for theVerne M. Willaman Chairs in Molecular
Biology and the Life SciencesTwo endowed professorships, with appoint-ment in the Department of Biology or theDepartment of Molecular and Cell Biology,arc available for pcrsons with research inter-ests in molecular biology and related areas ofthe life sciences, including biomolecularstruc-ture and function, gene regulation, develop-mental genetics, population genetics, andmolecular evolution.For information, contact:
Dr. Robert L Selander, Life Sciences SearchCommittee, Box WS, Department of Biology,208MucllerIaboratory,PennsylvaniaStateUni-versity, University Park, Pennsylvania 16802-5301. Phone: (814) 234-8997. FAX: (814) 863-4706.Dr. DonaldA. Bryant, MolecularBiology SearchCommittee, Box WS, Department of Molecularand Cell Biology, 108 Althouse Laboratory,Pennsylvania State University, University Park,Pennsylvania 16802-4500. Phone: (814) 865-1992. FAX: (814) 863-7024. Applications willbe accepted until vacancies are filled.
The Urnivriss an AdffirmsiwAaio/Equl COppmunay EmpLer.
WOMM and minuomic art enrutd to apply.
Associate Senior InvestigatorPharmacokinetics
The specific duties include: (i) design, conduct, analyze and report onhuman pharmacokinetics and toxicokinetic studies for Phase throughPhase IV drug development in collaboration with clinical research sci-entists including population pharmacokinetic and pharmacodynamicanalysis using appropriate statistical/pharmacokinetic software such asNONMEM; (ii) develop and coordinate comprehensive program ofpharmacokinetic studies for worldwide regulatory submission;and (iii)prepare reports of clinical pharmacokinetic and toxicokinetic studies,present research findings to scientific bodies and publish clinical phar-macokinetic studies in scholarly professional journals.Minimum requirements are a Ph.D. degree in Pharmacy or Pharma-ceutics and either two (2) years of experience in the job offered or two(2) years of experience in Clinical Pharmacy which shall include two (2)years graduate research experience in clinical pharmacokineticsinvolving (i) the application of basic and advanced clinical pharmacoki-netic theories including population pharmacokinetics and pharmacody-namics, (ii) the analyses of population pharmacokinetics data employ-ing nonlinear and mixed effects techniques and (iii) the use of pharma-cokinetic/statistical software packages. Must have published in thearea of advanced pharmacokinetic methods and population analysistechniques in scholarly professional journals. This experience may beacquired in conjunction with the required graduate education.Salary of $55,000 with employee benefits; M-F, 8am-4pm. No feecharged. For prompt and confidential consideration, submit resume orC.V. to The Phila. Job Bank, 444 N. 3rd St. - 3rd Fl., Phila., PA 19123and refer to Job Order Number 1539.
MAYO CLINIC SCOTTSDALEPOSTDOCTORAL FELLOWS IN
CELL AND MOLECULAR BIOLOGY
Positions available in collaborative researcheffort emphasizing transgenic approaches tostudy the molecular genetics of murine eosi-nophil differentiation and the interactions ofeosinophils with other components of theimmune system. Competitive salary and com-prehensive benefits package. Starting date isJanuary 1, 1994.Send curriculum vitae and names of threereferences to either:
Dr. James J. Lee or Dr. Nancy A. LeeDenartmnt ofBiochmtry and Molecular BiologySamuel C. Johnson Medical Research Center
Mayo Clinic Scottsdale13400 E. Shea Blvd.Scottsdale, AZ 85259
mawo
SAMUEL C. JOHNSON RESEARCH CEWTER MAYO CLIC SCO1TSDALEMayo Clinic Scottr&* is an Ai nalive AcioWEqual Opporty Empoyr
Structural Biological ChemistryFaculty Positions
The University of Texas Medical BranchGalveston, Texas
Multiple tenure-track faculty posibons at senior and junior ranks areavailable in areas involving the application of Nuclear Magnetic Reso-nance (NMR) to solving structure of biological macromolecules. TheUniversity of Texas Medical Branch has made a major commitment tocreate a strong Structural Biology Program on campus to enhance ourexisting capabilities. The NMR facility consists of new 400 and 600 MHzVarian spectrometers with a 750/800 MHz instrument contracted fordelivery in 1995. Endowed foundations, the Medical Branch and NIHfunding have provided excellent equipment, renovation funds, and spacein support of Structural Biology. The ultimate composition of the Unit willconsist not only of NMR spectroscopists, but also other disciplines relevantto Structural Biology, including computational chemistry and x-ray crystal-lography.Senior investigators with well established and productive research pro-gram are encouraged to apply. Successful junior candidates must haveoutstanding potential for independent research with a record and stature inthe field of NMR commensurate with the academic rank they are seeking.They will be expected to attract funding from national agencies and to fullyparticipate in graduate education at the departmental level. Affiliation withthe Sealy Center for Molecular Science or other relevant academic depart-ments will be available.Applications should include a complete curriculum vitae, a summary ofresearch interests and names and addresses of at least three references.Review of applications will continue until all positions are filled. Applica-tions should be addresses to:
Dr. James C. LeeStructural Biology Search Committee
Department of Human Biological Chemistry and Genetics andThe Scaly Center for Molecular ScienceUniversity of Texas Medical Branch F-47
Galveston, Texas 77555UTMB is an equal opportunity MIFN/IH affirmative action employer.UTMB hires only individuals authorized to work in the United States.
UTMB is a drug-free/smoke-free workplace.
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)_In preparation for the retirement of its current Director General, Dr. Nasrat Fadda, the Board of Trustees invites applications for
the post ofDIRECTOR GENERAL
Qualifications should include:* A distinguished career of professional achievement in any of the disciplines related to agricultural research relevant for dry
areas;
* Familiarity with West Asia/North Africa (WANA) Regions national agricultural research institutions and/or internationalorganizations;* An established record of institutional management at the highest level and of the leadership and motivation of a multi-
disciplinary and international staff of senior scientists and professionals, experience in inter-institutional networking and abilityto attract funding.Female candidates are welcome to apply.ICARDA, based on Aleppo, Syria, is one of 18 international centers belonging to the Consultative Group on InternationalAgricultural Research (CGIAR). It receives support from a large number of national and international donors. It has a professionalstaff of about 100 and an annual budget of 20 million dollars. The center is engaged in research and research associated trainingactivities to assist national efforts to increase food production and to conserve the natural resource base in the drier regions ofWest Asia and North Africa. Its research program includes germplasm enhancement of the region's most important food andfodder crops, farm resource management, socio-economics and public policy.The appointment of the new Director General will beforan initial five year term. Extension foran additional five year term is possibledepending upon accomplishments. Salary is open and commensurate with experience and qualifications. It is assumed that thesuccessful candidate will assume the position as at the beginning of 1995.
Further details can be obtained from the address below, where application with full C.V. and the names and addresses of threereferees should be received not later than August 15, 1993.
Prof. Dr. Winfried von UrffLehrstuhl fuer Agrarpolitik
D-8050 Freising-WeihenstephanGERMANY
_~~~~~~~~~~~~~CNS Research
A 2-year postdoctoral position inCNS pharmacology is currentlyavailable at ZENECA Pharmaceuti-cals Group (formerly ICI Pharma-ceuticals Group).Candidate will have a PhD or equiv-alent in the Biological Sciences. Astrong research background in neu-rophysiology with demonstratedknowledge of animal EEG experi-mentation is essential. You will beresponsible for the implementationof a state-of-the-art EEG laboratoryto conduct studies aimed at deter-mining dose-response and durationof action ofCNS compounds. Excel-lent oral and written communicationskills and the ability to interact withscientists in a multidisciplinaryenvironment are important.Interested candidates should sub-mit a c.v. to: Ron Martin, ZENECAPharmaceuticals Group, 1800 Con-cord Pike, Wilmington, DE 19897.
ZENECAPharmaceutIcals Group
ZENECA Pharmaceuticals/Stuart PharmaceuticalsBusiness Units of ZENECA Inc.
An Equal Opportunity Employer M/F.
RESEARCH SCIENTISTToxicology
Houghten Pharmaceuticals Inc. (HPI), aSan Diego-based drug discovery company,has a challenging opportunity for a scien-tist to support our rapidly expanding R&Defforts in the Preclinical DevelopmentDepartment.
Responsibilities include establishing apreliminary toxicology and pharmacoki-netic/pharmacodynamic in-house facility,generating protocols, monitoring toxicol-ogy studies at contract facilities, and pro-viding advice regarding regulatory strategy.
The ideal candidate will have a PhD inToxicology, preferably ABT certified;experience in an industrial setting, con-tract laboratory experience a plus; toxico-kinetic background; report-writing experi-ence; computer literacy; and excellentcommunication skills. Pharmacokinetic/pharmacodynamic and regulatory experi-ence are desirable.
HPI offers comprehensive benefits includingrelocation assistance, and equity partici-pation. For consideration, please submityour resume to: HoughtenHOUGHTEN HPHARMACEUTICALSINC., SMISCII6-4-93/RS-PC, 3550General Atomic-Ct., San Diego,CA 92121. EOEMIF/DN. Paceal, Inc.
CHAIRPERSON
SECTION OF PLANT BIOLOGYUNIVERSITY OF CAUFORNIA, DAVIS
The University of California, Davis invites applica-tions and nominations for Professor and Chairper-son of the Section of Plant Biology within the newlyreorganized Division of Biological Sciences. Thechairperson will be responsible for providing aca-demic and administrative leadership to promoteexcellence in teaching and research in the Section.Candidates must have active research programswith outstanding records of achievement in an areaof experimental plant biology such as cell andmolecular plant biology, developmental plant biol-ogy or physiology and biophysics.The section offers an undergraduate degree andserves as the administrative core of the GraduateGroup in Plant Biology a campus-wide unit whichoffers Master's and Pin.D. degrees. Due to recentretirements, there is an opportunity for significantrecruitment of new faculty. The section will bemoving to a new building in 1996.For the initial application,candidatesshould submita curriculum vita, a statement of their current re-search program, and a statement of their teachingand administrative experience and philosophy to:
Chair of the Search CommitteeSection of Plant BiologyUniversity of California
Davis, CA 95616Closing Date: Open until filled, but applicationsmust be received before September 1, 1993 to beassured of consideration.The University of California is interested in candi-dates who reflect the highest standards of scholar-ship and professional activities and does not dis-criminate on the basis of race, color, national origin,religion, sex, disability, age, or sexual orientation.The University of California is an Equal Opportu-nity/Affirmative Action Employer.
-c i
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SYMPOSIUM
Third International Symposium on Combination TherapiesNew and Emerging Uses for Biological Response Modifiers in the Treatment of
Cancer, AIDS and other Infectious Diseases
October 29-3 1, 1993 * J.W Marriott Hotel * Houston, Texas
Symposium ChairpersonsEnrico Garaci, M.D., C.N.R and the University ofRome "Tor Vergata," Rome, Italy
Allan L. Goldstein, Ph.D., The George Washington University School of Medicine, Washington, D.C.Adan Rios, M.D., OnCol Medical Associates, P.A., Houston, Texas
Presented by:
L.*fNOLGY&APING
In collaboration with
OnCol Medical Associates, P.A. George Washington University School of MedicineHouston, Texas Washington, D.C.
University of Rome "Tor Vergata" Consiglio Nazionale Delle Ricerche (C.N.R.)Rome, Italy Rome, Italy
National Institutes of Health/National Institute on AgingWorld Health Organization
Symposium Scientific Themes*Animal Models of Combination Therapies. * Clinical application of combination therapies in* Molecular, cellular and gene approaches. cancer treatment.
* Basic and experimental models of novel * Combination approaches in the treatment of AIDSimmuneconjugates and receptor agonists. and other infectious diseases.Synergy between new drugs, biological response * Future directions/Prospects.modifiers, and/or vaccines in combination therapies.
Registration Fees$300 Scientist (Industrial Firm)$200 Scientist (University, Government or other non-profit organization)$100 Student
For further information please contact:
Lynne K. Tiras, CMP or Karen Schmitt International Meeting Managers, Inc.
4550 Post Oak Place, Suite 248 Houston, TX 77027(713) 965-0566; FAX (713) 960-0488
jL i
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POSITIONS OPEN
PROJECT ECOLOGIST, Disney Wilderness Pre-serve, the Nature Conservancy. Scientist needed to de-sign and implement research and monitoring of criticalspecies, natural communities and restoration programson 10,000 plus-acre preserve. Will also coordinate dataanalysis, publish research results and develop educationtraining and outreach components of program. Ph.D.preferred with grant writing background and 3 to 5 yearsof experience. Send resume and cover letter to: JoraYoung, Department DP, The Nature Conservancy,2699 Lee Road, Suiite 500, Winter Park, FL 32789.
RESEARCH ECOLOGIST. The Nature Conser-vancy seeks a broadly trained plant or community ecol-ogist to conduct research and coordinate cooperatingscientists on a multidisciplinary longleaf pine ecosystemrestoration project. Ph.D. required; knowledge ofsouth-eastern United States ecosystems preferred. Position isfill-time and expected to last 3 to 5 years. Send applica-tions including curriculum vitae, statement ofexpenence,and 3 letters of reference by July 1, 1993, to: JeffreyHardesty, The Nature Conservancy, 118 Newins-Ziegler Hall, University of Florida, Gainesville, FL32611. The Nature Conservancy is an Equal OpportunityEmployer.
SCIENCES INTERNATIONAL, INC.A health and environmental sciences consulting com-
pany is hiring at all levels. Seeking experts in:Air Modeling
Risk Assessment of Hazardous Waste,Incinerators and PesticidesToucology/EpidemiologyEcological kisk Assessment
Aquatic BiologyIndividuals wishing to apply should submit their r6-
sumes to:Sciences International, Inc.
1001 19th Street North 7511 ArrowheadSuite 1500 Suites B and CArlington, VA 22209 Kennewick, WA 99336
ASSOCIATE BIO-STATISTICIAN to summarizeand statistically analyze clinical trials data. Duties includewriting programs in SAS under VAX/VMS to accessdatabase, summarizing and analyzing dinical data, andproducing customized statistical tables, graphs and datalistings. M.S. in Bio-Statistics or related field whichincludes research activity involving the application ofstatistical methods to large and complex databases and incommunication of statistical applications includingmethods to answer research questions and the results ofthose statistical procedures. Must have a working knowl-edge of SAS software with regard to the creation ofSASdata sets and the statistical analysis and summarization ofdata. Must also have knowledge of formatting data,design ofsummary tables, graphs and data listings. Salary$30,000 per year. 40 hours per week. Applicant shouldapply to nearest Job Service office or submit a resume to:Job Service, 700 Wade Avenue, Raleigh, NC 27605.Refer to Job Order No. NC 7225672 and DOT Code020.167-026. All resume must include applicant SocialSecurity Number.
The Biotechnology Patent Examining Group of thePatent and Trademark Office is currently recruiting sci-entists for ositions as PATENT EXAMINERS. nhdi-viduals wit advanced degrees and/or equivalent expen-ence in the fields of immunology, molecular biology,gene therapy, transgenic animals, animal science, bio-chemistry, protein engineering and microbiology areurged to send a resume or SF-171 to the followingaddress:
Patent and Trademark OfficeOffice of Personnel
Box 171Washington, DC 20231
K. Clark (180)For further information, call (703) 308-1123. U.S.
CITIZENSHIP IS REQUIRED FOR EMPLOYMENT.
COMPUTER MARKETPLACE
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SCIENCE * VOL. 260 4 JUNE 1993
SCIENCE welcomes placement of line classified adsby FAX. Please include name and telephone number forour confirmation call when transmitting ad to:
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I
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Simultaneous CD4, CD8 measurementsusing CD3 cells as the gate criteria.Whole blood was labeled with CD3-PE,CD4-Quantum Red and CD8-FITCin a single tube.
Quantum Red" tandem dye providesthree color capabilities for virtually allflow cytometers. Simultaneous analysisof multiple cell populations orfluorescence gating is now possible.Quantum Red Offers:* Lower emissions in PE channelcompared to other tandem dyes
* Less compensation required than inprevious generation third color dyes
* Equivalent brightness when compared to PE* Minimal compensation required for twocolor analysis with FITC labels
* Economical cost
Quantum Red is available conjugated to:* Streptavidin (Sigma Product No. S 3402)* Selected CD markers* Isotype controls
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