plenary speakers - nanostring
TRANSCRIPT
PRESENTED BY
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Alex Swarbrick, PhD
Associate Professor of Medicine at UNSW Sydney, Laboratory Head in the GarvanInstitute
of Medical Research, NHMRC Senior Research Fellow, Co-head of the Breast Translational
Oncology Program in the Kinghorn Cancer Center, Sydney, Australia
Carl June, MDDirector of the Center for Cellular Immunotherapies at the Perleman School of Medicine and
Director of the Parker Institute for Cancer Immunotherapy at the University of Pennsylvania
Paolo Ascierto, MDDirector, IRCCS Instituto Nazionale Tumori Fondazione G Pascale
Peggy Sotiropoulou, PhD
Director of Research & Development, Celyad, Mont-Saint-Guibert, Belgium
Aleix Prat, MD, PhD
Head Medical Oncology Department - Hospital Clinic of Barcelona, Head Translational Genomics
& Targeted Therapeutics in Solid Tumors Group, Institut d’Investigacions Biomèdiques August Pi i
Sunyer (IDIBAPS), Hospital Clinic of Barcelona, American Association for Cancer Research
Alessandra Cesano, MD, PhD
Chief Medical Officer at ESSA Pharmaceuticals
Moderators
Plenary Speakers
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SPEAKERS
Juraj Adamik, PhDResearch Scientist
Parker Institute for Cancer Immunotherapy
Jenny Cronin, PhDAssociate Product Manager
NanoString Technologies
Jan Davidson, MD, PhDSenior Director
Clinical Research, MacroGenics Inc.
Anushka Dikshit, PhDApplication Scientist
Advanced Cell Diagnostics
Kit Fuhrman, PhDGeoMX RNA Product Manager
NanoString Technologies
Sergio Rutella, MD, PhD, FRCPathProfessor of Cancer Immunotherapy
John van Geest Cancer Research Centre, School of
Science and Technology, Nottingham Trent University
William L. Hwang, MD, PhDClinical Fellow in Radiation Oncology
Massachusetts General Hospital, Radiation Oncology
Arutha Kulasinghe, PhDPeter Doherty NHMRC Early Career Fellow at the
Queensland University of Technology (QUT)
Lisa Rydén, MD, PhDProfessor i Kirurgi, Lund University, Medical
Faculty, dept of Clinical Sciences Lund, div of
Oncology and Surgery
Noemi Reguart, MD, PhDThoracic Oncology Consultant
Hospital Clínic de Barcelona
Erin Piazza, PhDSenior Bioinformatics Scientist
NanoString Technologies
Peter Nelson, MDProfessor of Medicine
University of Washington
E. Aubrey Thompson, PhDProfessor of Cancer Biology
Mayo Clinic Comprehensive Cancer Center
Jon Zugazagoitia, MD, PhDPhysician Scientist
Department of Medical Oncology Lung Cancer Unit
Dana Mustafa, PhDAssistant Professor
Group Leader of the Tumor Immuno-Pathology (TIP)
Laboratory, Erasmus University Medical Center
Melanie Spears, PhDPrincipal Research Scientist
Ontario Institute for Cancer Research
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Beijing CST Wednesday 20 May (11:00 AM-8:00 PM Beijing CST)
11:00 AM-1:00 PM Exhibits Hall/Poster Viewing/Networking
1:00 PM-1:45 PM Plenary Session. Speaker: Carl June
1:45 PM-2:00 PM Break
Spatial Biology Track Biomarker Discovery Track
2:00 PM-2:15 PM Moderator Alex Swarbrick Alessandra Cesano
The Promise of Spatial Biology Biomarker Discovery for Precision Medicine
2:15 PM-2:45 PM Speaker Alex Swarbrick Aubrey Thompson
Talk title:A Multi-omic single cell and spatial atlas of breast cancer reveals stromal suppression of anti-cancer immunity
Digital spatial mapping of the immune landscape of triple negative breast cancer reveals novel features of immune-tumor cell interaction
2:45 PM-3:15 PM Speaker William Hwang Jon Zugazagoitia
Talk title:
Single-nucleus RNA-seq reveals distinct intratumoral transcriptomic heterogeneity in treatment-naïve and chemoradiotherapy-treated primary pancreatic ductal adenocarcinoma
Discovery of biomarkers associated with benefit from PD-1 checkpoint blockade in non-small-cell lung cancer (NSCLC) using high-plex digital spatial profiling
3:15 PM-3:45 PM Break
3:45 PM-4:15 PM Speaker Arutha Kulasinghe Melanie Spears
Talk title:Highly multiplexed digital spatial profiling of the tumor microenvironment of head and neck squamous cell carcinoma patients treated with immune checkpoint therapy
Assessing immune biomarkers of response to anthracyclines in breast cancer
4:15 PM-4:45 PM Speaker Anushka Dikshit Dana Mustafa
Talk title:Molecularly Guided High Plex Spatial Profiling in the Tumor Microenvironment
The Immune Microenvironment of Pancreatic Cancer
4:45 PM-5:15 PM Speaker Kit Fuhrman Erin Piazza
Talk title:Cancer Transcriptome Atlas with NGS Readout – The essential tool for spatial genomics in oncology
Tumor Signaling 360 Panel: A 360° View of Altered Signaling Pathways in Cancer
5:15 PM-6:00 PM Exhibits/Poster Session/Networking
AGENDA
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Beijing CST Thursday 21 May (11:00 AM-7:30 PM Beijing CST)
11:00 AM-1:00 PM Exhibits Hall/Poster Viewing/Networking
1:00 PM-1:45 PM Plenary Session Speaker: Paolo Ascierto
1:45 PM-2:00 PM Break
Immuno-Oncology Track Clinical Applications Track
2:00-2:15 PM Moderator Peggy Sotirpoulou Aleix Prat
Advances in Immuno-oncology Leveraging Signatures in the Clinical Setting
2:15 PM-2:45 PM Speaker Peter Nelson Aleix Prat
Talk title:Spatial landscape of the immune microenvironment in metastatic prostate cancer using GeoMx™ Digital Spatial Profiler
Primary results of SOLTI-1402/CORALLEEN phase 2 trial of neoadjuvant ribociclib plus letrozole versus chemotherapy in PAM50 Luminal B early breast cancer: an open-label, multicenter, two-arm, randomized study
2:45 PM-3:15 PM Speaker Sergio Rutella Noemi Reguart
Talk title:Immune infiltration correlates with TP53 mutational status in a multi-cohort acute myeloid leukemia study
Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
3:15 PM-3:45 PM Break
3:45 PM-5:15 PM Speaker Juraj Adamik Lisa Rydén
Talk title:Molecular and Immunologic Profiling of CD8 T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
Comparison of PAM50 intrinsic subtype profiles in matched primary and metastatic breast cancer samples from the CTC-MBC trial (NCT01322893) shows a significant shift towards more aggressive subtypes throughout tumor progression
5:15 PM-5:45 PM Speaker Jenny Cronin Jan Davidson
Talk title:GeoMx® Protein Offerings: Fully validated antibodies to meet your spatial profiling needs
Flotetuzumab (FLZ), an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells and CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment in Primary Refractory AML Patients
5:45 PM-6:30 PM Exhibits/Poster Session/Networking
AGENDA
Presenters Title
Dan Zollinger NanoString Technologies
Molecularly guided digital spatial profiling for highly multiplexed analysis of gene expression with spatial
and single cell resolution
Heather Ann Brauer NanoString Technologies
Using multi-omic profiling to unravel the complexity of triple-negative breast cancer (TNBC)
Sarah Church NanoString Technologies
Deep Spatial Profiling of the Immune Landscape of MSI and MSS Colorectal Tumors
Jessie Perez NanoString Technologies
Transcriptomic Characterization of Immune Response within Diverse Tumor Environments using the
NanoString® nCounter® PanCancer IO 360™ Assay
Yugi Ren NanoString Technologies
Genomic Characterization of Breast Cancer Heterogeneity using Breast Cancer 360™
Alan Huang NanoString Technologies
Fusion Gene Detection in Cell-free Plasma by NanoString Low Input Fusion assay
Parick Danaher NanoString Technologies
Updating immune cell deconvolution for the spatial genomics era
Jason Reeves NanoString Technologies
Enabling pathway analysis of RNA expression in formalin-fixed paraffin embedded tissues with the GeoMx™
DSP platform
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APR 2020 MK2433
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