plaque shift
DESCRIPTION
A case presentation of plaque shiftTRANSCRIPT
CASE PRESENTATIONCASE PRESENTATION
ByDr. Khalid Iqbal BhattiPost Fellow
SequenceSequenceIntroductionClinical HistoryClinical ExaminationLabsImagesDiscussionFollow-up
Clinical HistoryClinical History52 YearsKnown case of diabetes mellitus
for 14 yearsKnow case of hypertension for 1
yearNon smokerNon AsthmaticNo previous History of IHD
Clinical HistoryClinical Historycontd…contd…Chest pain/heaviness for 3 to 4
hours radiating both arms relieved by nitrates
During admission pain recurred Associated with sweating
Clinical ExaminationClinical ExaminationPulse 72 beats/minBP 110 / 70 mmHgRR 22 breaths/minCVS UnremarkableECG ST depression in V2 – V5
LabsLabsTroponin less than 0.05
ng/mlRoutine investigations
Normal
SummarySummary52 yrs present with USA having
multiple risk factors and ECG changes
Recommended for Coronary cath
ImagesImagesCoronary Angiography
DiscussionDiscussion
Plaque shiftPlaque shiftThe lateral dislocation of plaque during dilatation therapy, which if directed towards a side branch, may occlude the ostium
Snow-plow injury Snow-plow injury a form of plaque shift that occurs at the carina of the bifurcation where plaque is dislocated from the parent vessel into the ostium of the side branch
Predictors of side Predictors of side branch branch occlusionocclusionSeveral mechanisms are
responsible for SB compromising during bifurcation treatment:◦ Plaque shift “snow plow effect ”◦ Dissection of SB after balloon/stent
in MB◦ Spasm of SB◦ SB ostium jailing by stent struts◦ Carina stent-induced displacement
Characteristics of bifurcation Characteristics of bifurcation lesions PCIlesions PCI
Identification of Side Branch Identification of Side Branch at riskat risk
Identification of Side Branch Identification of Side Branch at riskat riskSB Occlusion during PCI
Plaque Shift At Plaque Shift At Bifurcation LesionsBifurcation LesionsPCI of Bifurcation lesion is
challengingSide-branch compromise in 9-67%
of casesProtection of side branches is time
consuming, associated with more contrast media, radiation, and increased risk of complications as dissection, perforation, CIN
In bifurcation lesions in which there is no significant involvement of the side branch, we cannot predict the fate of the side-branch after PCI
Plaque Shift At Plaque Shift At Bifurcation LesionsBifurcation LesionsIntra-coronary near-infrared
spectroscopy can identify lipid-core plaques using the Lipiscan (InfraRedx) system
Lipid-core plaques are soft, and prone to plaque shift during PCI
Side-branch compromise as a result of plaque shift is associated with increased rate of peri-procedural MI and other complications
Near-infrared spectroscopy can potentially help to identify bifurcation lesions that are in increased risk of side-branch compromise
Both plaque shift from the MB and carina shift contribute to the creation / aggravation of a SB ostial lesion after MB stent implantation.
The mechanism of side branch(SB) luminal narrowing after main branch(MB) stent implantation in coronary bifurcation lesions is not completely understood.
Management / ProtectionManagement / ProtectionAccurate stent positioningProtect side-branch with wireNitrates to exclude spasmKissing PTCA to side-branchStent occasionally requiredIVUS
Follow-UpFollow-UpClinically
◦No symptoms◦No serial ECG changes◦Vitally stable ◦Observe for 24 hours◦Glycoprotein IIb / IIIa inhibitor
20
THANKSTHANKS