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Physiology ofRespiratory

SystemBy

Mila Citrawati

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Boyles Law

P =1/V

Plays role in process of inspirationn expiration

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Laplaces LawP = 2T/r

Pressure inside a spherical structure is directly

proportional to tension in wall and inerselyproportional to radius of sphere

!ithout surfactan" surface tension in #oth

aleoli $s%all and lar&e' is the sa%e( ) &reaterpressure is re*uired to +eep s%all aleolusopen( ,%all aleolus tends to e%pty intolar&er one

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Poiseuilles Law-esistance to la%inar .ow is inersely

proportional to tu#e radius to the thpowerand directly proportional to the len&th of thetu#e( !hen radius is haled" resistance isincreased 10fold( f driin& pressure isconstant" .ow will fall to one sixteenth(3ou#lin& len&th only dou#les resistance( fdriin& pressure is constant" .ow will fall toone half

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3altons LawPartial pressure of a &as is the pressure

contri#uted #y a sin&le &as in a %ixture of&ases( 4ach of the &ases contri#utes to thetotal pressure in proportion to its relatiea#undance(

)t%ospheric pressure $506 %%7&' = P82$59"0:' ; P:' ;PC

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7enrys LawThe a%ount of a particular &as in solution is

directly proportional to the partial pressure ofthat &as

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Control of -espirationCentral che%oreceptors respond to chan&es in

arterial PC

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Control of -espiration1( nade*uate entilation for #odily needs %ay

depress P

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Control of -espiration( %pulses fro% carotid and aortic #odies

reach respiratory center ia&lossopharyn&eal and a&us nere(

>( %pulses fro% central che%oreceptors reachrespiratory center

0( %pulses fro% repiratory centers descend in

spinal cord to reach diapra&% ia phrenicneres and intercostal %uscles iaintercostal neres to increase rate anda%plitude of respiration(

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Control of -espiration5( )ccelerated respiration i%proes entilation

and thus tends to nor%aliAe P

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:

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-estrictie Pul%onary

3iseasei#rosis" aleolar wall thic+enin&

ncrease in the connectie tissue of the lun&

-educed lun& co%pliance3ecrease in TLC and VC

VC is %ar+edly decrease