physio brs important tables

8/15/2019 Physio BRS Important Tables

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Chapter 1

Type Electrochemica

l gradient

Carrier

mediated

Metabolic

energy

Na+

gradient

Inhibition of

Na-K pump

Simple diffusion Donhill No No No --

!acilitated

diffusion

Donhill "es No No --

#rimary acti$e %phill "es "es -- Inhibits

Cotransport %phill& "es Indirect "es' Same

direction

Inhibits

Countertranspor

t

%phill& "es Indirect "es'

(pposite

direction

Inhibits

&(ne or more solutes are transported uphill) Na+ is transported donhillTable ** - Characteristics of Different Types of Transport

E,ample ction Effect on Neuromuscular Transmission

.otulinus to,in .loc/s release of Ch from

presynaptic terminals

Total bloc/ade

Curare Competes ith Ch for

receptors on motor end plate

Decreases si0e of E##) ma,imal doses

produce paralysis of respiratory muscles

and death

Neostigmine Inhibits acetylcholinesterase #rolongs and enhances action of Ch at

muscle end plate

1emicholinium .loc/s reupta/e of choline

into presynaptic terminal

Depletes Ch stores from presynaptic

terminalTable *2 - gents ffecting Neuromuscular Transmission

!eature S/eletal Cardiac Smooth

ppearance Striated Striated No striations

%pstro/e of

action potential

Inard Na+

current

Inard Ca2+ current 3S node4

Inard Na+ current 3atria' $entricles'

#ur/in5e fibers4

Inard Ca2+ current

#lateau No No 3S node4

"es 3atria' $entricles' #ur/in5e fibers)

due to inard Ca2+ current4

No

Duration of

action potential

6* msec *78 msec 3S node' atria4

2789:88 msec 3$entricles and

#ur/in5e fibers4

6*8 msec

E,citation9

contraction

coupling

ction potential

-; T tubules

Ca2+ released

from nearby S<'

Inard Ca2+ current during plateau

of action potential

Ca2+-induced Ca2+ release from S<

= >Ca2+?i

ction potential

opens $oltage-gated

Ca2+ channels in

cell membrane



= >Ca2+?i

Molecular basis

for contraction

Ca2+9troponin C Ca2+9troponin C Ca2+9calmodulin =

myosin light-chain

/inase

Table *: - Comparison of S/eletal' Smooth' and Cardiac Muscle



Chapter 4 - Respiratory System



Chapter 2 - Cardiac Physio



Chapter 6 - GI

physio brs important tables

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