phylogeographic and genome-wide investigations …10.1038...phylogeographic and genome-wide...

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Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic movements Pischedda S, Barral-Arca R, Gómez-Carballa A, Pardo-Seco J, Catelli ML, Álvarez-Iglesias V, Cárdenas JM, Nguyen ND, Ha HH, Le AT, Martinón-Torres F, Vullo C, Salas A Supplementary Data Figure S1. Phylogenetic networks of HVS-I mtDNA Vietnamese sequences. Figure S2. Maximum parsimony trees based on CR sequences representing haplogroup M7b1a1f (A) and F1f (B). See Figure 3 for more information. Figure S3. EBSPs (with 95% CI) of haplogroup F1f and M7b1a1f obtained from complete mitogenomes. Figure S4. EBSP of main Vietnamese ethnics. Figure S5. MDS plot of IBS values considering different SEA populations (Table S2) and one European (CEU) and one African population (YRI).

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Page 1: Phylogeographic and genome-wide investigations …10.1038...Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic

Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic movements

Pischedda S, Barral-Arca R, Gómez-Carballa A, Pardo-Seco J, Catelli ML,

Álvarez-Iglesias V, Cárdenas JM, Nguyen ND, Ha HH, Le AT, Martinón-Torres

F, Vullo C, Salas A

Supplementary Data

Figure S1. Phylogenetic networks of HVS-I mtDNA Vietnamese sequences.

Figure S2. Maximum parsimony trees based on CR sequences representing

haplogroup M7b1a1f (A) and F1f (B). See Figure 3 for more information.

Figure S3. EBSPs (with 95% CI) of haplogroup F1f and M7b1a1f obtained from

complete mitogenomes. Figure S4. EBSP of main Vietnamese ethnics.

Figure S5. MDS plot of IBS values considering different SEA populations (Table

S2) and one European (CEU) and one African population (YRI).

Page 2: Phylogeographic and genome-wide investigations …10.1038...Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic

Figure S1.

Page 3: Phylogeographic and genome-wide investigations …10.1038...Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic

Figure S1.

Page 4: Phylogeographic and genome-wide investigations …10.1038...Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic

Figure S2.

Page 5: Phylogeographic and genome-wide investigations …10.1038...Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic

Figure S3.

0 2000 4000 6000 8000 10000

5e+0

32e

+04

5e+0

42e

+05

5e+0

52e

+06

Years before present

Fem

ale

effe

ctive

pop

ulat

ion

size

x g

M7b1a1f MeanM7b1a1f Median

0 2000 4000 6000

1e+0

35e

+03

2e+0

45e

+04

2e+0

55e

+05

Years before present

Fem

ale

effe

ctive

pop

ulat

ion

size

x g

F1f MeanF1f Median

A

B

Page 6: Phylogeographic and genome-wide investigations …10.1038...Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic

Figure S4.

Page 7: Phylogeographic and genome-wide investigations …10.1038...Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic

Figure S5.

0.00 0.05 0.10 0.15

−0.1

0−0

.05

0.00

0.05

Dimension 1 (10.58%)

Dim

ensi

on 2

(3.8

7%)

0.00 0.05 0.10 0.15

−0.1

0−0

.05

0.00

0.05

Dimension 1 (10.58%)

Dim

ensi

on 2

(3.8

7%)

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EuropeCEUAfricaYRIChinaCHSCDXMalaysiaBidayuhNegritoMalayProto−MalayPhilippinesAytaAgtaAtiIrayaMinanubuMamanwaFilipinoThailandHmong (Miao)KarenLawaMlabriMonPaluangPlangTai KhuenTai LueH'tinTai YuanTai YongYaoVietnamKHV