phrm 826 lecture _ skin hair nails part i (1)

41
Gail D. Newton, Ph.D., R.Ph. ASSESSMENT OF COMMON SKIN, HAIR, AND NAIL DISORDERS

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Page 1: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

G a i l D . N e w t o n , P h . D . , R . P h .

ASSESSMENT OF COMMON SKIN, HAIR, AND NAIL DISORDERS

Page 2: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

LECTURE OBJECTIVES

• Recognize the signs and symptoms of common dermatological disorders.

• Identify the causes of common dermatological problems.

• Recognize dermatological signs and symptoms that warrant referral to a primary care provider.

• Given a case, determine the most likely cause of the patient’s dermatological problem.

• Given a case, determine whether or not a patient’s dermatological condition warrants referral to a primary care provider.

Page 3: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

WHAT IS THIS?

Which of the following is a picture of poison ivy dermatitis?

A B C

Page 4: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

CONTACT DERMATITIS

• Defined as skin eruptions that develop as a result of a substance coming into contact with the skin

• Irritant contact dermatitis (ICD) is secondary to exposure to soaps, detergents and organic compounds.

• Allergic contact dermatitis (ACD) is secondary to exposure to any substance that triggers an allergic response such as plant resins, latex and certain metals

Page 5: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

IRRITANT CONTACT DERMATITIS

Acute ICD

Chronic ICD

Page 6: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

IRRITANT CONTACT DERMATITIS

“New Shirt” ICD

“Lip Lickers” ICD

Page 7: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

ALLERGIC CONTACT DERMATITIS

ACD: Nickel

Page 9: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

CONTACT DERMATITIS

• Treatment

• Avoidance

• Antihistamines

• Topical Steroids

• Oral Steroids

• Topical Astringents

• Topical Protectants

• Referral

• Signs of Infection

• Large Area of Involvement

• Interference With Activities of Daily Living

• Extensive Swelling

Page 10: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

HOW DO I GET RID OF THIS?

Which of the following would not require medical referral?

A B C

Page 11: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

ACNE

• androgenic hormones

• increased sebum production

• follicle growth

• Propionibacterium acnes

Page 12: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

ACNE

Page 13: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

ACNE

Type 1 Comedones only; <10 lesions on the face; no lesions on the trunk; no scarring

Self-treatment

Benzoyl peroxide Salicylic acid Sulfur/resorcinol Azelaic acid Tretinoin

Type 2 Papules; 10-25 lesions on face and trunk; mild scarring

Refer to physician

Topical antibiotics

Type 3 Pustules; >25 lesions; moderate scarring

Refer to physician

Oral antibiotics Topical therapy

Type 4 Nodules or cysts; extensive scarring

Refer to physician

Isotretinoin Systemic hormones

Treatment

Page 14: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

ACNE

• Type 1: Open Comedones Only

• Type 1: Closed Comedones Only

Page 15: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

ACNE

• Type 2 Acne • Type 3 Acne

Page 16: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

ACNE

• Type 4 Acne • Type 4 Acne

Page 17: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

• Dermatophytoses are the most common disorders of the skin.

• The most common causes are Epidermophyton, Microsporum and Trichophyton Species.

• These may be transmitted from fomites, animals and the soil.

• The three most common types of dermatophytosis are tinea pedis, tinea corporis, and tinea cruris.

Page 18: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

• Require a warm moist environment and an avenue into the stratum corneum

• Presentation is different depending upon the dermatophye and infection site

Page 19: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

Page 20: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

• Risk Factors

• Immunosuppression

• History of atopic dermatitis

• Warm, humid climates

• Occlusive clothing and footwear

• Obesity

Page 21: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

Page 22: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

Page 23: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

Page 24: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

• Treatment

• Astringents

• Antifungals

• Clean, dry clothing

• Prevention

• Referral

• Signs of Infection

• Large Area of Involvement

• Interference With Activities of Daily Living

• Extensive Swelling

Page 25: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

FUNGAL SKIN INFECTIONS

• Referral

• Scalp involvement

• Nail involvement

• Immune suppression

• Multiple diseases

• Diabetes

Page 26: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

HOW DO I GET RID OF THIS?

Which of the following would not require medical referral?

A B C

Page 27: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

PEDICULOSIS

• Pediculosis refers to louse-borne infestations.

• There are three types of lice that are common in the US.

• Head lice (pediculosis capitis)

• Body lice (pediculosis corporis)

• Pubic lice (pediculosis pubis)

• Pubic lice can also infest other hairy areas such as the eyelashes and axilla.

• Body lice infestations can be eradicated without drug therapy.

Page 28: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

PEDICULOSIS

• Risk Factors

• Close physical contact

• Sharing infested combs, hats, clothing, bedding, etc.

• Multiple sexual partners

Page 29: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

PEDICULOSIS

Page 30: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

PEDICULOSIS

Page 31: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

PEDICULOSIS

• Treatment

• Pediculocides

• Total nit removal

• Environmental Decontamination

• Prevention

Page 32: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

PEDICULOSIS

• Referral

• Eyelash involvement

• > 2 treatment failures

• Evidence of secondary infection

• Systemic symptoms

Page 33: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

WHAT ABOUT MY BABIES?

•Household pets with fur must also be treated with lice.

A. True

B. False

Page 34: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

SKIN CANCER

• There are three types of skin cancer that are common in the US.

• Basal Cell Carcinoma (BCC)

• Squamous Cell Carcinoma (SCC)

• Melanoma

• The American Cancer Society estimates that 850,000 cases of BCC, 250,000 cases of SCC and 60,000 cases of melanoma are diagnosed annually.

Page 35: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

SKIN CANCER

• Risk Factors• Fair skin

• History of sunburn

• Excessive UV exposure

• Presence of moles

• Family History

• Personal History

Page 36: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

SKIN CANCER

• BCC may appear as a

• pearly or waxy bump

• flat, flesh-colored or brown scar-like lesion

• single ulceration with a rolled border

Page 37: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

SKIN CANCER

BCC BCC

Page 38: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

SKIN CANCER

• SCC may appear as a

• firm, red nodule.

• flat lesion with a scaly, crusted surface.

Page 39: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

SKIN CANCER

SCC SCC

Page 40: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

SKIN CANCER

• Melanoma signs include(a)

• large brownish spot with darker speckles

• mole that changes in color, size or feel or that bleeds.

• small lesion with an irregular border and portions that appear red, white, blue or blue-black.

• dark lesions on the palms, soles, fingertips or toes, or on mucous membranes lining the mouth, nose, vagina or anus.

Page 41: PHRM 826 Lecture _ Skin Hair Nails Part I (1)

“ABCDE” Rule for Skin Cancer