phencyclidine induced psychosis resembles schizophrenia

PHENCYCLIDINE INDUCED PSYCHOSIS RESEMBLES SCHIZOPHRENIA Nine patients who abused phencyclidine (phencyclohexyl piperidine) developed an acute psychosis resembling acute schizophrenia and so provided an intriguing drug m<Xle1 for the disease. The pat i en ts were agitated. hostile. ex hibited tangentiality. circumstantiality and were preoo:upied with religious and sexual topi CS. Seven of the 9 had delus ional ideas (predominantly religious grandiosity and delusions of influence), 6 patients had auditory hallucinations. 3 were su ic idal and 4 disorientated in at least I sphere. Duration of psychosis ra n ged from 6 to 90 days. Treatment with antipsychoti c dru gs was aeneraHy ineffective and those who recovered did so gradually. All en, R.M. and Young. SJ ., Amer ieanJQurnal ofPsychialIy 1H : 108 L (Sep 1978) 0156·2703/79/ 0120-0005 $00.50/ 0 C ADIS Press INPHARMA 20 J an 1 979 5

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PHENCYCLIDINE INDUCED PSYCHOSIS RESEMBLES SCHIZOPHRENIA

Nine patients who abused phencyclidine (phencyclohexyl piperidine) developed an acute psychosis resembling acute schizophrenia and so provided an intriguing drug m<Xle1 for the disease. The patients were agitated. hostile. exhibited tangentiality. circumstantiality and were preoo:upied with religious and sexual topiCS. Seven of the 9 had delusional ideas (predominantly religious grandiosity and delusions of influence), 6 patients had auditory hallucinations. 3 were suicidal and 4 disorientated in at least I sphere. Duration of psychosis ranged from 6 to 90 days. Treatment with antipsychotic drugs was aeneraHy ineffective and those who recovered did so gradually. Allen, R.M. and Young. SJ., AmerieanJQurnal ofPsychialIy 1 H : 108 L (Sep 1978)

0156·2703/79/ 0120-0005 $00.50/ 0 C ADIS Press INPHARMA 20 Jan 1979 5

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