pharmacoepidemiology and drug safety

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, VOL 2, 523-554 (1993)

CURRENT AWARENESS

Pharmacoepidemiology and Drug Safety

1 BOOKS, REVIEWS & SYMPOSIA

Special issue - A Symposium: QT(c) Interval Prolongation: Is it bene ficial or harmful? Amer J Cmdiol 1993; 72: (6)

Special issue: Hepato-biliary toxicity of medications, industrial chemicals and medicinal plants (Articles in French with English Ab- stract). Gasrroen CIin Biol 1993; 17: (SBIS)

Special issue: Ototoxicity. Otolafyngol CIin Nrh Amer 1993; 2 6 (5) Angermeyer MC, Daumer R, Matschinger H. Abt Psychiat Soziol,

Zent Inst See1 Gesundheit, Postfach 122120, D-68072 Mannheim, FRG. Benefits and risks of psychotropic medication in the eyes of the general public - Results of a survey in the Federal Republic of Germany. P h m a c o p s y c h i a ~ 1993; 2 6 (4) I 14

Ayalon D, Pines A. Ichilov Hosp, Tel Aviv Med Ctr, Timsit Inst Reprod Endocrinol, 6 Weizmann St, IL-64239 Tel Aviv, Israel. Cardiovascular disease and hormone replacement therapy: A review. Isr J MedSci 1993; 2 9 (10) 660

Baciewicz AM, Baciewicz FA. Univ Hosp Cleveland, Dept Pharm Serv, Cleveland, Oh 44106, USA. Ketoconazole and fluconazole drug interactions (Review). Arch Intern Med 1993; 153: (17) 1970

Barnes PJ, Pedersen S. Natl Heart & Lung Inst, Dept Thorac Med, Dovehouse St, London SW3 6LY, England. Special issue: Efficacy and safety of inhaled corticosteroids in asthma: Report of a work- shop held in Eze, France, October 1992. Amer Rev Resp Dis 1993;

Baniere SL. Synergen, Med Affairs, 1885 33rd St, Boulder, Co 80301, USA. Review of in vifro activity, phannacokinetic characteristics, safety, and clinical efficacy of cefprozil, a new oral cephalosporin. A n n Pharmacother 1993; 27: (9) 1082

Barrio G, De la Fuente L, Cami J. Univ Autonoma Barcelona, Inst Municipal Invest Med, Paseo Martimo 25, E-08003 Barcelona, Spain. The consumption of drugs in Spain and its position in the European context (Review) (Spanish, English Abstract). Med CIin 1993; 101: (9) 344

Becker BN, Fall P, Hall C, Milam D, Leonard J, Glick A, Schulman GI. 'Vanderbilt Univ, Med Ctr, Dept Med, Div Nephrol, S-3223 Med Ctr Nth, Nashville, Tn 37232, USA. Rapidly progressive acute renal failure due to acyclovir. Case report and review of the literature. Amer JKidney Dis 1993; 22: (4) 61 1

Berger 0, Ziko U, Jellinger K, Machacek E, Grisold W. Kaiser Franz Josef Spital, Neurol Abt, Kundratstr 3, A-I100 Vienna, Aus- tria. Necrotizing myopathy due to cholesterol-lowering agents - A case report and review of the literature (German). Nervenarrt 1993, 64: (8) 539

Bielecki JW, Filippini L*. 'Kantonsspital, Med Klin, Gastroenterol Abt, CH-6004 Luzem, Switzerland. Side effects of non-steroid anti-inflammatory drugs (NSAID) on the lower intestinal tract (Re- view) (German, English Abstract). Schweiz Med Wochenrchr 1993; 123: (29) 1419

148: (4 Suppl)

Bircher AJ. Petersgraben 4, CH-4031 Basel, Switzerland. Delayed hypersensitivity to heparins (Review) ( G e m , English Abstract). AI- Iergologie 1993; 16: (7) 268

Brien JA. Monash Univ, Victorian Coll Pharm, Sigma Dept Pharm Practice, 381 Royal Parade, Parkville, Vic 3052, Australia. Mo- toxicity associated with dicylates - A brief review. Drug safep 1993; 9 (2) 143

Brinton LA, Schairer C. NCI, Environm Epidemiol Branch, Execut Plaza N, Rm 443, Bethesda, Md 20892, USA. Estrogen replacement therapy and breast cancer risk. Epidemiologic Rev 1993; 15 (1) 66

Coleman MD. Univ Aston, Dept Pharmaceut Sci, Mech Drug Toxic Grp, Birmingham B4 7ET, England. Dapsone: Modes of action, toxicity and possible strategies for increasing patient tolerance ( R e view). Brit J Demtol1993; 129 (5) 507

Collins DM, Gidal BE*, Pitterle ME, *Univ Wisconsin, Sch Pharm, Ctr HIth Sci, 425 Nth Charter St, Madison, Wi 53706, USA. Po- tential interaction between carbamazepine and loxapine: Case report and retrospective review. Ann Phannacother 1993; 27: (10) I I80

Comelison TL, Reed E*. *NCI, Med Branch, kthesda, Md 20892, USA. Nephrotoxicity and hydration management for cisplatin, carboplatin, and ormaplatin (Review). Cynecol Oncol 1993; 50: (2) 147

Daniels S, Schentag JJ. SmithKline Beecham Pharmaceut, Welwyn Garden City AL7 IEY, Herts, England. Drug interaction studies and safety of famciclovir in healthy volunteers - A review. Anrivir Chem Chemother 1993; 4 (Suppl 1) 57

D'Arcy PF. Queens Univ Belfast, Belfast BT7 INN, Northem Ire- land. Adverse reactions and interactions with herbal medicines. 2. Drug reactions (Review). Ahterse Drug React Toxic Rev 1993; I 2 (3) 147

Donovan S, McGrady H, Pownall R, Rees JA. Boots Pharmaceut, Res Dept, Nottingham NG2 3AA, England. The efficacy and tolerability of dothiepin and 3 selective serotonin reuptake inhibitors in the treatment of major depression - A review of 6 doubleblind studies. Curr Ther Res 1993; 54: (3) 275

Ellis M, Ravid M, Lishner M*. *Meir Hosp, Dept Med, IL44281 Kefar Sava, Israel. A comparative analysis of alkylating agent and epipodophyllotoxin-related leukemias (Review). Leuk Lymphoma

Farmr HC, Walsh-Sukys MC, Kyllonen K, Blumer JL*. *Rainbow Babies & Childrens Hosp, Div Pediat Pharmacol & Crit Care, 2074 Abington Rd, Cleveland, Oh 44106, USA. Cardiac toxicity associated with intravenous erythromycin lactobionate - 2 case reports and a review of the literature. Pediat Inf Dis J 1993; 12 (8) 688

Foulds RA. SmithKline Beecham Pharmaceut, Welwyn Gdn City AL7 IEY, Herts, England. An overview of human safety data with

1993; 11: (1-2) 9

In order to keep subscribers up-to-date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 19 sections: 1 Books, Reviews & Symposia; 2 General; 3 Anti-infective Agents; 4 Cardiovascular System Agents; 5 C N S Depressive Agents; 6 Non-steroidal Anti-inflammatory Agents; 7 CNS Agents; 8 Anti-neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator-Blocking Agents; 1 1 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti-inflammatory Agents - Steroi- dal; 19 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

CCC 1053-8569193104-50523-32 0 1993 by John Wiley & Sons, Ltd.

524 CURRENT AWARENESS IN PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

nedocromil sodium. JAIlerg CIin Immunol 1993; 92: (1) 202 Halevy S, Shai A. Ben Gurion Univ Negev, Fac Hlth Sci, Kupat

Holim, Soroka Med Ctr, Dept Dermatol, POB 151, IL-84101 Beer Sheva, Israel. Lichenoid drug eruptions (Clinical Review). J Amer AcadDermafoll993; 2 9 (2 Pt 1) 249

Halpem SM, Fitzpatrick R, Volans GN. Guys Hosp, Poisons Informat Sew, London SEI 9RT, England. Ibuprofen toxicity - A review of adverse reactions and overdose (Review). Adverse Drug React Toxic Rev 1993; 12 (2) 107

Hansen BJ, Rosenberg J*. *Hvidovre Univ Hosp, Dept Surg Gas- troenterol 235, DK-2650 Hvidovre, Denmark. Persistent postoperative hiccups - A review. Acta Anaesthesiol Scund 1993; 37: (7) 643

Hellenbrecht D. Klinikum Univ, Zentrum Pharmacol, Theodor Stem Kai 7, D-60596 Frankfurt, FRG. Benefits and risks of systemic and local non-steroidal anti-inflammatory drugs (NSAIDs) (Review) (German, English Abstract). Med KIin 1993; 88: (9) 532

Herren T, Como F, Krahenbuhl S, Wyss PA*. 'Schweiser Toxikol Informat Zentrum, Klosbachstr 107, CH-8030 Zurich, Switzerland. Management of salicylate intoxication (Review) (German, English Abstract). Schweiz Med Wochemchr 1993; 123: (38) 1775

Hoehns JD, Perry PJ*. *Univ Iowa, Coll Pharm, 2271 Quadrangle, Iowa City, Ia 52246, USA. Zolpidem: A nonbenzodiazepine hyp- notic for treatment of insomnia (Drug Review). Clin Pharmacy 1993; 1 2 (11) 814

Hofer CA, Smith JK, Tenholder MF*. *Vet Affairs Med Ctr, Pulm Dis Sect 11 IH, 1 Freedom Way, Augusta, Ga 30910, USA. Vera- pamil intoxication: A literature review of overdoses and discussion of therapeutic options. Amer J Med 1993; 9 5 (4) 431

Holt D, Harvey D, Hurley R. Queen Charlottes & Chelsea Hosp, Inst Obstet & Gynecol, RPMS, Karim Ctr Meningitis Res, Goldhawk Rd, London W6 OXG, England. Chloramphenicol toxicity (Re view). Adverse Drug React Toxic Rev 1993; 12: (2) 83

Iredale JP, George CF. Southampton Gen Hosp, Southampton SO9 4XY, England. Drugs causing gastrointestinal obstruction (Re view). Adverse Drug React Toxic Rev 1993; 12: (3) 163

Jenkinson T, Bhalla AK*. *Royal Natl Hosp Rheumat Dis, Upper Borough Walls, Bath BAI IRL, England. A reappraisal of steroid- induced osteoporosis (Review). Brit J Hosp Med 1993; S O (8) 472

Kellihan MJ. Univ Louisville, James Graham Brown Canc Ctr, Div Med Oncol Hematol, Louisville, Ky 40292, USA. Drug formulary review process for sargmnostim and filgrastim: Focus on analysis of adverse drug reactions. Clin Ther 1993; 15: (5) 927

Khalil H, Molinary E, Stoller JK*. *Cleveland Clin Fdn, Dept Pulm & Crit Care Med, A90, 9500 Euclid Ave, Cleveland, Oh 44195, USA. Diclofenac (voltaren>induced eosinophilic pneumonitis - Case report and review of the literature. Arch Intern Med 1993; 153: (14) 1649

Kumana CR, Li KY, Kou M. Univ Hong Kong, Dept Med, Pokfulam Rd, Hong Kong, Hong Kong. Do chloramphenicol blood dy- scrasias occur in Hong Kong? (Review). Adverse Drug React Toxic Rev 1993; 1 2 (2) 97

Lanvl FL. 6630 Demoss, Houston, Tx 77074, USA. Gastrointestinal toxicity of newer NSAIDs (Review). Amer J Gasfroenferal 1993; 88: (9) 1318

Launchbury AP, Habboubi N. Farmital Carlo Erba Ltd Ital, House 23, Grosvenor Rd, St Albans ALI 3AW, England. Epirubicin and doxorubicin - A comparison of their characteristics, therapeutic activity and toxicity (Review). Cancer Trearment Rev 1993; 1 9 (3) 197

Leddin DJ. Victoria Gen Hosp, 4087 Dickson Ctr, Halifax, Nova Sco- tia, Canada B3H 2Y9. Prophylaxis of NSAID-associated gastroduodenal damage: A critical review of risk factors. Can J Gar- rroenferol 1993; 7: ( 5 ) 440

Lewis RV, Lofthouse C. Pontefract Dist Gen Hosp, Friarwood Lane, Pontefract WF8 IPL, England. Adverse reactions with p-adrenoceptor blocking drugs: An update (Review). Drug Safety 1993; 9 (4) 272

Liebelt EL, Shannon MW. Childrens Hosp Med Ctr, Div Emergency Med, 300 Longwood Ave, Boston, Ma 021 15, USA. Small doses, big problems: A selected review of highly toxic common medications. Pediarr Emerg Care 1993; 9 ( 5 ) 292

Mahoney K, Scales MDC*, Tucker ML. *Glaxo Grp Res Ltd, Ware SG12 ODP, Hem, England. Impurities in organic synthetic drugs - A review of regulatory and toxicological considerations. Adverse Drug React Toxic Rev 1993; 12 (2) 129

Malone KE, Daling JR, Weiss NS. Fred Hutchinson Canc Res Ctr, Div Pub1 Hlth Sci, 1124 Columbia St, MP381, Seattle, Wa 98104, USA. Oral contraceptives in relation to breast cancer. Epid- emiologic Rev 1993; 15: (1) 80

Malone KE. Fred Hutchinson Canc Res Ctr, Div Pub1 Hlth Sci, 1124 Columbia St, MP381, Seattle, Wa 98104, USA. Diethylstilbestrol (DED) and breast cancer. Epidemiologic Rev 1993; 15 (1) 108

Middleton RM, Kirkpatrick MB. USAF, Med Ctr, Med Procedures Clin, Keesler AFB, Ms 39534, USA. Clinical use of cocaine - A review of the risks and benefits. Drug Safety 1993; 9 (3) 212

Mills CM, Marks R. Univ Hosp Wales, Dept Dermatol, Heath Pk, Cardiff CF4 4XW, Wales. Adverse reactions to oral retinoids: An update (Review). Drug Safety 1993; 9 (4) 280

Misbah SA, Chapel HM*. *John Radcliffe Hosp, Dept Immunol, Level 7, Oxford OX3 9DU, England. Adverse effects of intravenous immunoglobulin (Review). Drug Safity 1993; 9 (4) 254

Neubert R, Fritzsch B, Dongowski G. Martin Luther Univ Halle Wit- tenberg, Inst Pharmazeut Techno1 & Biopharm, Fachbereich Pharm, D-06120 Halle, FRG. Interactions between food ingredients and drugs (Review) (German, English Abstract). Phurmazie 1993; 48: (10) 723

Newbold RR. NIEHS, E4-04, POB 12233, Res Triangle Pk, NC 27709, USA. Gender-related behavior in women exposed prenatally to diethylstilbestrol (Review & Commentary). Environ Health Perspect 1993; 101: (3) 208

Olbricht T, Benker G. Univ Essen Gesamthsch, Dept Med, Hufelandstr 55, W-4300 Essen 1, FRG. Glucocorticoid-induced osteoporosis - Pathogenesis, prevention and treatment, with special regard to the rheumatic diseases (Review). J Intern Med 1993; 234: (3) 237

Ophaswongse S, Maibach H*. *Univ Calif San Francisco, Sch Med, Dept Dermatol, Box 0989, San Francisco, Ca 94143, USA. Topical nonsteroidal antiinflammatory drugs - Allergic and photoallergic contact dermatitis and phototoxicity (Review). Contact Dermatitis 1993; 2 9 (2) 57

Opie LH. Univ Cape Town, Med Res Council, Ischem Heart Dis Res Unit, Cape Town, Rep Sth Africa Special issue: Interactions with cardiovascular drugs. Curr Prob Curdiologv 1993; 1 8 (9) 533

Patsalos PN, Duncan JS. Univ London, Inst Neurol, Dept Clin Neurol, Epilepsy Res Grp, Pharmacol & Therapeut Unit, Queen Sq, London WClN 38G, England. Antiepileptic drugs - A review of clinically significant drug interactions (Review). Drug Safety 1993; 9: (3) 156

Periti P, Mazzei T, Mini E, Novelli A. Univ Firenze, Dipt Farmacol, viale Morgagni 65, 1-50134 Florence, Italy. Adverse effects of macrolide antibacterials (Review). Drug safety 1993; 9 (5) 346

Pineo GF, Hull RD. Calgary Gen Hosp, Bow Valley Ctr, D4-009, 841 Ctr Ave East, Calgary, Alberta, Canada T2E OAl. Adverse effects of coumarin anticoagulants (Review). Drug Safety 1993; 9 (4) 263

Rennie IG. Univ Shefield, Royal Hallamshire Hosp, Dept Ophthal- mol & Orthopt, Glossop Rd, Shefield S10 2JF, England. Clini- cally important ocular reactions to systemic drug therapy (Review). Drug Safety 1993; 9 (3) 196

Rodvold KA, Piscitelli SC. Univ Illinois, Coll Pharm, Dept Pharm Practice, Rm 176, 833 S Wood St, Chicago, 11 60612, USA. New oral macrolide and fluoroquinolone antibiotics - An overview of pharmacokinetic, interactions, and safety. CIin Infect Dis 1993; 17: (Suppl 1) S192

CURRENT AWARENESS M PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 525

Rossi SJ, Schroeder TJ, Hariharan S, First MR*. *Univ Concinnati, Med Ctr, Dept Internal Med, Div Nephrol & Hypertens, 231 B e thesda Ave, Cincinnati, Oh 45267, USA. Prevention and management of the adverse effects associated with immunosuppressive therapy (Review). Drug &fey 1993; 9 (2) 104

Rush CR, Higgins ST, Bickel WK, Hughes JR. Francis Scott Key Med Ctr, Behav Pharmacol Res Unit, 5510 Nathan Shock Dr, Ste 3000, Baltimore, Md 21224, USA. Abuse liability of alpramlam relative to other commonly used bemdiazepines: A review. Neurosci Biobehav Rev 1993; 17: (3) 277

Sabbatini M, De Nicola L, Sansone G, Conte G+. *Univ Naples, Fac Med 1, Dept Nephrol, 1-80138 Naples, Italy. Renal hypoperfusion as the primary cause of cyclosporin-induced nephropathy (Mitorial Review). Nephrol Diabsis Transplant 1993; 8: (9) 794

Sacristan JA, Soto JA, De Cos MA. Lilly SA Clin Res Dept, Pharma- coecon Unit, Avda Ind 30, E-28100 Alcobendas, Spain. Erythro- mycin-induced hypoacusia - 11 new cases and literature review. Ann Pharmacother 1993; 27: (7-8) 950

Sena MM, Pashko S. Ctr Hlth Res, Reston, Va 22090, USA. Drug utilization review using a Medicaid claims database. Clin 7’her 1993; 15: (5) 900

Stanford JL, Thomas DB. Fred Hutchinson Canc Res Ctr, Div Pub1 Hlth Sci, 1124 Columbia St, MP381, Seattle, Wa 98104, USA. Exogenous progestins and breast cancer. Epidemiorogic Rev 1993; 15: ( I ) 98

Stevens MCG, Brandis M. Childrens Hosp, Dept Oncol, Ladywood Middleway, Birmingham B16 8ET, England. Incidence and etiol- ogy of ifosfamide nephrotoxicity: Report of a meeting held in Rhodes, Greece, October 3, 1991, sponsored by Asta-Medica, Frankfurt, Germany. Med Pediat Oncoll993; 21: (9) 640

Szmidt M, Gmlewska-Rqmowska I, Rozniecki J. Clin TB & Lung Dis 2, 181 Okolnastr, PL-91520 Lodz, Poland. Tolerance to aspirin in aspirin-sensitive asthmatics - Methods of inducing the tolerance state and its influence on the course of asthma and rhinosinusitis (Review). J Invest Allerg CIin ImmunoI1993; 3: (3) 156

Taylor JW, Bell AJ. Univ Mississippi, Dept Clin Pharm Practice, 2500 Nth State St, Jackson, Ms 39216, USA. Lithium-induced parathyroid dysfuncion - A case report and review of the literature. Ann Pharmacother 1993; 27: (9) 1040

Thompson DF. SW Oklahoma State Univ, Dept Pharm Practice, Weatherford, Ok 73096, USA. Drug-induced parotitis (Review). J Clin Pharm Ther 1993; 18: (4) 255

Thompson JW, Jacobs RF*. *Arkansas Childrens Hosp, 800 Marshall St, Little Rock, Ar 72202, USA. Adverse effects of newer cepha- losporins - An update (Review). Drug &fey 1993; 9 (2) 132

Treskes M, Van der Vijgh WJF. Free Univ Amsterdam Hosp, Dept Oncol, De Boelelaan 1117, 1081 HV Amsterdam, The Nether- lands. WR2721 as a modulator of cisplatin- and carboplatin-induced side effects in comparison with other chemoprotective agents: A molecular approach (Review). Cancer Chemother Phar- macoll993; 33: (2) 93

Verdi CJ. Arizona Canc Ctr, 1501 Nth Campbell Ave, Tucson, Az 85724, USA. Cancer therapy and oral mucositis - An appraisal of drug prophylaxis (Review). DrugSafey 1993; 9 (3) 185

Vicari G. 1st Super Sanita, 1-00161 Rome, Italy. Virological safety aspects of plasma derivatives - November 1992, Cannes, France (Meeting Report). BioIogicals 1993; 21: (1) 85

2 GENERAL

Adverse Drug Reactions Advisory Committee. Long-standing adverse reactions. Med J Australia 1993; 159 (9) 621

Alderman J. Pfizer Inc, New York, NY, USA. Drug interactions - The death pen (Letter). J A m MedAssn 1993; 270: (1 1) 1316

Allen JE. Univ Utah Hosp, Dept Pharm Serv, Drug Infonnat Serv, A-050 50 Nth Med Dr, Salt Lake City, Ut 84132, USA. Drug-induced photosensitivity. Clin Pharmacy 1993; 12: (8) 580

Ansell BM. Consulting Rooms, 9 Beaumont Rd, Windsor SL4 IHY, England. Drug-induced systemic lupus erythematosus in childhood (Editorial). Lupus 1993; 2 (3) 139

Ansell BM. Consulting Rooms, 9 Beaumont Rd, Windsor SL4 IHY, England. Drug-induced systemic lupus erythematosus in a 9 year old boy. Lupu~ 1993; 2: (3) 193

Aronson J. Radcliffe Infirm, Oxford OX2 6HE, England. Serious drug interactions. Practitioner 1993; 237: (1 53 I ) 789

Auriche M, Loupi E*. *Pasteur Merieux Serums & Vaccines, Dept Postmkt Surveillance, Dept Pharmacocovigilance, F-69007 Lyon, France. Does proof of causality ever exist in phannacovigilance? Drug &fey 1993; 9 (3) 230

Baker KR. Address not available. A possible hazard in labeling of generic products (Letter). PoslgradMed 1993; 94: (5) 34

Bowen JD, Larson EB. Pacific Med Ctr, 1200 12th Ave S, Seattle, Wa 98144, USA. Drug-induced cognitive impairment - Defining the problem and finding solutions. Drug Aging 1993; 3: (4) 349

Brillet G, Stephan D, Imbs JL*, Andrejak A, Baumelou A, Briand Y, Brillet G, Caron J, ChaumeTriffaud M, Deray G et al. *CHRU Strasbourg, Inst Pharmacol, BP 426, F-67091 Slrasbourg, France. Mechanisms, prediction and prevention of drugs nephrotoxicity (French, English Abstract). Therupie 1993; 48: (4) 321

Burns RJ, Schultz DW. Flinders Univ Sth Australia, Med Ctr, Bed- ford Pk, SA 5042, Australia. Drug-induced neurological disorders. Med JAwtralia 1993; 159 (9) 624

Cappell MS, Simon T. UMDNJ, Robert Wood Johnson Med Sch, Dept Med Gastroenterol, New Brunswick, NJ 08903, USA. Colo- nic toxicity of administered medications and chemicals. Amer J Gastroenterol 1993; 88: (10) 1684

Choo V. Address not available. Transnational pharmacovigilance (News). Lancet 1993; 342: (8874) 798

Cohen MR, Davis NM. Inst Safe Medicat Practices Inc, 1143 Wright Dr, Huntingdon Valley, Pa 19006, USA. Pharmacists must receive all incident reports involving medications (Letter). Amer J Hosp Pharm 1993; 5 0 (8) 1575

Cook M, Ferner RE*. *Dudley Rd Gen Hosp, Birmingham B18 7QH, England. Adverse drug reactions - Who is to know? Brit Med J 1993; 307: (6902) 480

Costa PF. Janssen Pharmaceut Inc, Titusville, NJ, USA. Drug interactions - The death pen (Reply). J Am Med Assn 1993; 270 (11) 1316

De Jong-van den Berg L. Univ Groningen, Univ Ctr Phann, Dept Pharmacol & Pharmacotherapeut, Antonius Deusinglaan 2, 9713 AW Groningen, The Netherlands. Drug utilization studies in pregnancy - What can they contribute to safety assessment? (Doctoral Thesis). Pharm WorldSci 1993; 15: (4) 171

De Jong-van den Berg LTW, Waardenburg CM, Haaijer-Ruskamp FM, Dukes MNG, Wesseling H. Univ Groningen, Dept Pharmacol & Pharmacotherapeut, Pharm & SOC Sect, Antonius Deusinglaan 2, 9713 AW Groningen, The Netherlands. Drug use in pregnancy - A comparative appraisal of data collecting methods. Eur J Clin Phar- macoll993; 4 5 ( I ) 9

Dillner L. Address not available. Inquiry says depot injections can kill (News). Brit Med J 1993; 307: (6905) 641

Dongari A, McDonnell HT, Langlais RP. Univ Texas, San Antonio Dent Sch, Hlth Sci Ctr, Dept Periodont, 7703 Floyd Curl Dr, San Antonio, Tx 78284, USA. Drug-induced gingival overgrowth. Oral Surg Oral Med Oral Pathol 1993; 7 6 (4) 543

Dove FB. Address not available. Drug-induced lupus (Letter). Hosp Pract 1993; 2 8 (8) 14

Edwards R. WHO Collaborating Ctr Int Drug Monitoring, Uppsala, Sweden. Competing in drug safety (Commentary). Lancet 1993; 342: (8872) 631

Faich GA. Corning Pharmaceut Serv, St Davids, Pa, USA. Postmar- keting surveillance: Beyond Medwatch (Letter). J Am Med Assn 1993; 270 (18) 2180

Ganzini L, Millar SB, Walsh JR. Dept Vet Affairs Med Ctr, Psychiat

526 CURRENT AWARENESS IN PHARMACOEPIDEMIOLffiY AND DRUG SAFETY

Sew, 3710 SW US Vet Hosp Rd, Portland, Or 97207, USA. Drug- induced mania in the elderly. Drug Aging 1993; 3: (5) 428

Gelenberg AJ. Univ Arizona, Arimna Hlth Sci Ctr, Dept Psychiat, 1501 N Campbell Ave, Tucson, Az 85724, USA. Postmarketing surveillance - Perspectives of a journal editor (Commentary). P p chopbmacol Bull 1993; 29: (1) 135

Gelfand MS, Lancaster DJ. Methodist Hosp, Memphis, Tn 38014, USA. Drug interactions - The death pen (Letter). J Am Med Assn 1993; 270 (1 1) 1316

Gerl A, Wilmanns W. Univ Munich, Klinikum Grosshadern, Med Klin 3, Marchioninistr 15, D-81377 Munich, FRG. Drug-induced immune hemocytopenia (Letter) (German, English Abstract). Deur Med Wochenrchr 1993; 118 (27-28) 1048

Giannini EH, Cassidy JT, Brewer El, Shaikov A, Maximov A, Kuzmina N. Childrens Hosp Med Ctr, Div Rheumatol, Pav 1-129, Elland & Bethesda Ave, Cincinnati, Oh 45229, USA. Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis. Smin Arthritis Rheum 1993; 23: (1) 34

Gibson PR, Fraser JRE, Colman JC, Jones PA, Jennings G, Dudley FI. Royal Melbourne Hosp, Dept Med, Parkville, Vic 3050, Aus- tralia. Change in serum hyaluronan - A simple index of short term drug-induced changes in hepatic sinusoidal perfusion. Gusrroen- terology 1993; 105: (2) 470

Goldstein DJ, Wilson MG. Eli Lilly & Co, Lilly Res Lab, Lily Corp Ctr, Indianapolis, In 46285, USA. Adverse event frequencies gen- erate hypotheses of effiacy and safety (Commentary). CIin Phur- mucol Ther 1993; 54: (3) 245

Goyan JE. Alteon Inc, 165 Ludlow Ave, Northvale, NJ 07647, USA. Withdrawal of a drug from the market: What should the prescriber do? (Editorial). JAmer Med Assn 1993; 270 (16) 1976

Grasela TH, Walawander CA, Kennedy DL, Jolson HM. SUNY, Dept Pharm, 319 Cooke Hall, Buffalo, NY 14260, USA. Capability of hospital computer systems in performing drug use evaluations and adverse drug event monitoring. Amer J Harp Phurm 1993; 50: (9) 1889

Guess HA. Merck Res Labs, CB 7400, McGavran Greenberg Hall, Chapel Hill, NC 27599, USA. How should acute hepatic drug effects be studied epidemiologically? (Editorial). Epidemiologv 1993; 4 (6) 487

Inman W, Pearce G. Drug Safety Res Unit, Nurlesdon Hall, Southampton SO3 8BA, England. Prescriber profile and post-marketing surveillance. Luncet 1993; 342: (8872) 658

John D. Address not available. Doctor who found thalidomide dan- gers is shuck off (News). Brit MedJ 1993; 307: (6901) 404

Johnson J, Tanner LA. US FDA, Ctr Drug Evaluat & Res, Div Epidemiol, HFD-730, Rm 15531, Rockville, Md 20857, USA. Postmarketing surveillance: Curriculum for the clinical pharma- cologist. 1. Postmarketing surveillance within the continuum of the drug appmval process. J CIin Pharmucol1993; 33 (10) 904

Jorgensen TM, Isacson DGL, Thorslund M. Univ Uppsala, Div Social Pharm, BMC, Box 586, S-75123 Uppsala, Sweden. Prescription drug use among ambulatory elderly in a Swedish municipality. Ann Phurmucother 1993; 27: (9) 1 120

Kaufman DW, Kelly JP, Johannes CB, Sandler A, Harmon D, Stolley PD, Shapiro S. Boston Univ, Sch Pub1 Med, Slone Epidemiol Unit, 1371 Beacon St, Brookline, Ma 02146, USA. Acute thrombocytopenic purpura in relation to the use of drugs. Blood 1993; 82: (9) 2714

Kennedy DL, Tanner LA, Barash D, Goetsch RA. US FDA, Off Commissioner, Rm 14-62, HF-2, 5600 Fishers Lane, Rockville, Md 20857, USA. National adverse drug event reporting. Amer J HospPhunn 1993; 50: (9) 1913

Kessler DA. US FDA, Rockville, Md 20857, USA. Postmarketing surveiilance: Beyond Medwatch (Reply). J Am Med Assn 1993; 270 (18) 2180

Kimbel KH. Address not available. 25 years of spontaneous ADR reporting (News). Lancet 1993; 342: (8874) 798

Kitani H, Kajimoto I, Sugimoto K, Mifune T, Mitsunobu F, Yokota S, Hiramatsu J, Kawaraya M, Tanizaki Y. Okayama Univ, Sch Med, Div Med, Misasa Med Branch, 827 Yamada Misasa, Tottori 68201, Japan. IgE-mediated allergic reaction in drug-induced asthma. Actu Med ORayomu 1993; 47: (5) 317

Koren G. Hosp Sick Children, Dept Pediat, 555 Univ Ave, Toronto, Ontario, Canada M5G 1x8. Medications which can kill a toddler with one tablet or teaspoonful. J Toxicol-Clin Toxicol 1993; 31: (3) 407

Korn EL, Yu KF, Miller LL. NCI, Biometr Res Branch, Canc Ther- apy Evaluat Program EPN-739, Bethesda, Md 20892, USA. Stop- ping a clinical trial very early because of toxicity - Summarizing the evidence. Con& Cfin Trial $993, 14: (4) 286

Lebelle MJ. Dept Hlth, Bur Drug Res, Div Pharmaceut Chem, Banting Bldg, Tunneys Pasture, Ottawa, Ontario, Canada KIA OL2. Drug names and medication errors: Who is responsible? (Edi- torial). Can MedAssn J 1993; 149 (7) 941

Lee WM. Univ Texas, SW Med Ctr, Dept Internal Med, Div Liver, 5323 Hany Hines Blvd, Dallas, Tx 75235, USA. Drug-induced hepatotoxicity. Aliment Phurmacol7llerapeut 1993; 2 (5) 477

Lenert, Markowitz, Blaschke. Address not available. Primum non no- cere? Valuing of the risk of drug toxicity in therapeutic decision making (Clin Phurmucol Ther 1993, 53 285) (Correction). Clin Phurmucol Ther 1993; 54: (1) 64

Livingston J, Reeves RD*. *Kansas State Univ Agr & Appl Sci, Dept Foods & Nutr, Manham, Ks 66506, USA. Undocumented potential drug interactions found in medical records of elderly patients in a long-term care facility. J Amer Diet Assn 1993; 93: (10) 1168

Manojlovic Z, Vrhovac B*, Manojlovic S. *Univ Zagreb, Sch Med, Dept Med, Clin Pharmacol Sect, Kispaticeva 12, Zagreb, Croatia. Qualitative analysis of drug prescription in a geriatric population sample. Inr JCIin Phurm Ther Toxicol 1993; 31: (9) 430

Martin SD. Glenbourne Unit, Plymouth PL6 5AF, England. Drug-induced parotid swelling (Letter). Brit J Hosp Med 1993; 50: (7) 426

McDonald E, Marino C. Address not available. Drug-induced lupus (Reply). Hosp Pruct 1993; 2 8 (8) 14

Mutasim DF, Pelc NJ, Anhalt GJ. Univ Cincinnati, Med Ctr, Dept Dermatol, 234 Goodman St, Pavillion A-3, Cincinnati, Oh 45267, USA. Drug-induced pernphigus. Dermufol CIin 1993; 11: (3) 463

Nimmo SM, Kennedy BW, Tullett WM, Blyth AS, Dougall JR. Western Infirm & Associated Hosp, Intens Therapy Unit, Dumbar- ton Rd, Glasgow GI 1 6NT, Scotland. Drug-induced hyperthermia (Case Report), Anaesthesia 1993; 48: (1 0) 892

Nordby El, Wright PH, Schofield SR. 6234 S Highlands, Madison, Wi 53705, USA. Safety of chemonucleolysis - Adverse effects re- ported in the United States, 1982-1991. CIin Orthop Reluted Res 1993; (293) 122

Papoz L. MSERM, U21, 16 Ave Paul Vaillant Couturier. F-94807 Villejuif, France. Utilization of drug sales data for the epidemiology of chronic diseases: The example of diabetes. Epidemiology 1993; 4 (5) 421

Peck CC, Temple RJ, Collins JM. US FDA, Rockville, Md 20857, USA. Drug interactions - The death pen (Reply). J Am Med Assn 1993; 270 ( 1 1 ) 1317

Petri H. Univ Limburg, Dept Epidemiol, POB 616, 6200 MD Maas- tricht, The Netherlands. The prescription drug history in pharmacoepidemiology (Doctoral Thesis). Phurm World Sci 1993; IS: (4) 176

Ross-Degnan D, Soumerai SB*, Fortess EE, Gunvitz JH. *Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, 126 Brookline Ave, Ste 200, Boston, Ma 02115, USA. Examining product risk content: Market withdrawal of zomepirac as a case study. J Amer MedAssn 1993; 270 (16) 1937

Shader RI. Greenblatt DJ. Address not available. Medwatch, the new FDA adverse effects reporting system (Editorial). J CIin Psycho- phurmucol1993; 13: (5) 303

Srinivas KR. Address not available. Politics of biosafety and regula-

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tory mechanisms: Japanese vaccine trials in India (Commentary). Econ Polit wky 1993; 2 8 (36) 1850

Stewart GE, Lockey RF. Univ Sth Florida, Coll Med, Tampa, FI 33612, USA. Reduction of side effects of specific immunotherapy (Reply). JAllerg Clin Immunol 1993; 92: (3) 498

Strom BL, Gibson GA. Univ Penn, Sch Med, Ctr Clin Epidemiol & Biostat, 221L NEB, Philadelphia, Pa 19104, USA. A systematic integrated approach to improvement of drug prescribing in an acute care hospital - A potential model for applied hospital pharmacoepidemiology. CIin Phannocol mer 1993; 54: (2) 126

Thomson AN, Barham PM. Univ Tasmania, Dept Community Hlth & Gen Practice, 43 Collins St, Hobart, Tas 7000, Australia. The effect of a warning about putative adverse events on drug prescribing in general practice. Soc Sci Med 1993; 37: (7) 883

Toll J, Llorens MJ, Borrell F, Paredes I. ABS La Gauarm, Barcelona, Spain. The Guillain-Bme syndrome - Clinical suspicion of adverse reaction to a drug (Letter) (Spanish, English Abstract). Med CIin 1993; 101: (7) 275

Turpin JC, Dubois G. CHU Reims, Hop Robert Debre, Sew Neurol, rue Alexis Carrel, F-51092 Reims, France. Inborn or drug-induced lipidosis - Differential diagnosis (French, English Abstract). Presse Medicale 1993; 2 2 (25) 1 183

USP Subcommittee on Toxicity and Cell Cultures. Safety and effeo tiveness of pharmaceuticals: A statement on a potential approach to alternatives to animal testing. Phannacopeial Forwn 1993; 19 (2) 5075

Wantke F, Demmer CC, Gotz M, Jarisch R. Dermatol & Pediat Al- lergy Clin, Vienna, Austria. Reduction of side effects of specific immunotherapy (Letter). J Allerg Clin Immunoll993; 92: (3) 497

Wilkinson SM, Smith AG, Davis MJ, M a w DL, Dawes PT. Skin Hosp, Chapel St, Salford M60 9EP, England. Suspected cutaneous drug toxicity in rheumatoid arthritis - An evaluation. Brit J Rheu- mat01 1993; 3 2 (9) 798

Williams KG. Univ Wyoming, POB 3375, Laramie, Wy 82071, USA. Absence of liability in Illinois for failing to warn of a drug interaction. Amer JHosp Phann 1993; 50: (10) 2095

Wodtke JM, Generali JA*. *Univ Kanw, Med Ctr, Dept Pharm, 39th & Rainbow Blvd, Kansas City, Ks 66103, USA. Use of medical record codes to identify adverse drug reactions. Amer J Hosp Pharm 1993; 50. (9) 1915

Woolf AD, Lovejoy FH. Childrens Hosp Med Ctr, Dept Me4 300 Longwood Ave, Boston, Ma 021 IS, USA. Epidemiology of drug overdose in children. Drug Safely 1993; 9 (4) 291

Yawata M. Address not available. Deaths due to drug interaction (News). Lancet 1993; 342: (8880) 1166

3 ANTI-INFECTIVE AGENTS

Isoniazid-induced hepatotoxicity (Letter). Mt Sinai J Med 1993; 60:

Aigrain EJ, Brun P, Bennasr S, Loirat C. Hop Robert Debre, Dept Clin Pharmacol, F-75019 Paris, France. Side effects of pefloxacin in idiopathic nephrotic syndrome (Letter). Lancer 1993; 342 (8868) 438

Alegre J, De Sevilla TF, Falco V, Armadans L, Vazquez JMM. Univ Autonoma Barcelona, Hosp Valle Hebron, Barcelona, Spain. Post- prandial serum cholyglycine as a marker of antituberculous drug hepatotoxicity in HIV-infected patients (Letter). Chest 1993; 104: (4) 1312

Alhnan C, Biour M, Grange JD. Hop Bicetre, Sew Malad Foie & Appareil Digesti, 78 rue Gen Leclerc, F-94275 Le Kremlin Bicetr, France. Hepatic toxicity of antituberculous agents - Responsibility of different drugs 199 cases (French, English Abstract). Presse Medicale 1993; 2 2 (26) 1212

Amita DB, Danon YL, Garty BZ. Bedinson Med Ctr, Dept Dermatol, IL-49100 Petah Tiqwa, Israel. Kawasaki-like syndrome associated with griseofulvin treatment (Letter). Clin Exp Dermatol 1993; 1 8

(4) 337

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New York, NY 10003, USA. Pancreatitis possibly related to 2'-3'- dideoxycytidine (Letter). Ann Intern Med 1993; 119 (6) 539

Arasteh KN, Vohringer HF, Slratmann MM, Tschechne BK, Heise WS, Lage MP. Auguste Viktoria Krankenhaus, Dept Internal Med, Rubensstr 125, D-12157 Berlin, FRG. Pharmawkinetics and adverse reactions of various dosage regimens of intravenous pen- tamidme in the treatment of HIV-associated Pnemocysttis cminii pneumonia: A nonrandomised open pilot study. Drug Invest 1993; 6 (4) 207

Arayne MS, Sultana N. Univ Karachi, Dept Chem, Univ Rd, Karachi 75270, Pakistan. Erythromycin-antacid interaction. Phannazie 1993; 48: (8) 599

Atali M, Israeli E, Abend Y, Gelner D. Kaplan Hosp, Dept Internal Med C, IL-76100 Rehovot, Israel. Trimethoprim/sulfamethoxamle- induced rash, fever, abnormal liver function tests, leukopenia, and thrombocybpenia. Ann Phannacother 1993; 27: (9) 1139

Azevedo E, Ribeiro JA, Polonia J, Pontes C. Hop Sao Joao, Fac Med, Dept Neurol & Neurosurg, Oporto, Portugal. Probable exacerbation of myasthenia gravis by ofloxacin (Letter). J Neurol 1993; 240: (8) 508

Baciewicz AM, A s h BH, Locke TW. Univ Hosp Cleveland, Cleve- land, Oh 44106, USA. Interaction of ofloxacin and warfarin (Let- ter). Ann Intern Med 1993; 119 (12) 1223

Belsito DV. N W Med Ctr, Dept Dermatol, 550 1st Ave, New York, NY 10016, USA. Contact urticaria from pentamidine isethionate. Contact Dem'r i s 1993; 2 9 (3) 158

Belzer F. Univ Wisconsin Hosp, Dept Surg, Madison, Wi 53792, USA. Neomycin toxicity in bladder irrigation (Comment). J Urol 1993; 150: (4) 1199

Betkowski AS, Lubin A. Mt Sinai Med Ctr, Div Hematol, Cleveland, Oh 44106, USA. Sulfamethomlerelated antiplatelet antibody (Letter). Blood 1993; 82: (5) 1683

Blaha JD, Calhoun JH, Nelson CL, Henry SL, Seligson D, Esterhai JL, Heppenstall RB, Mader J, Evans RP, Wilkins J el al. West Virginia Univ, Dept Moped, Hlth Sci Ctr, POB 9196, Morgan- tom, WV 26506, USA. Comparison of the clinical effcacy and tolerance of gentamicin PMMA beads on surgical wire versus combined and systemic therapy for osteomyelitis. Clin Orthop Re- lated Res 1993; 295 8

Borhani H, Peyman GA', Wafapoor H. *Louisiana State Univ, Med Ctr, Sch Me4 Eye Ctr, 2020 Gravier St, Ste B, New Orleans, La 70112, USA. Use of vancomycin in vitrectomy infusion solution and evaluation of retinal toxicity. Inf ophthamol 1993; 17: (2) 85

Boudreau E, Schuster B, Sanchez J, Novakowski W, Johnson R, Red- mond D, Hanson R, D a w l L. Pharmaceut Syst Inc, 927 BN Russell Ave, Gaithersburg, Md 20879, USA. Tolerability of pro- phylactic Lariam6 regimens. Trop Med Parasirol 1993; 44: (3) 257

Boutros N, Keck BP. Address not available. Delirium following influenza vaccination (Letter). Amer J Psychiaf 1993; 150: ( 12) 1 899

Calandra T, Zinner SH, Viscoli C, De Bock R, Gaya H, Meunier F, Klastersky I, Glauser MP, Ninove D, Langenaeken J et at. Picower Inst Med Res, 350 Community Dr, Manhasset, NY 11030, USA. Efficacy and toxicity of single daily doses of amikacin and ceftiaxone versus multiple daily doses of amikacin and ceftazidine for infection in patients with cancer and granulocytopenia. Ann In- rern Med 1993; 119 (7 Pt 1) 584

Carson JL, Strom BL, Duff A, Gupta A, Shaw M, Lundin FE, Das K. Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Div Gen Internal Me4 97 Patemn St, New Bmswick, NJ 08903, USA. Acute liver disease associated with erythromycins, sulfonamides, and tetracyclines. Am Intern Med 1993; 119 (7 Pt 1) 576

Catnach SM, Ballinger AB, Stevens M, Fairclough PD*, Trembath RC, Drury PL, Watkins PJ. 'St Bartholomews Hosp, Dept Gas- troenterol, West Smithtield, London ECIA 7BE, England. Erythro-

528 CURRENT AWARENESS IN PHARUQCOEPIDEMIOLOGY AND DRUG SAFETY

mycin induces supranormal gall bladder contraction in diabetic autonomic neuropathy. Gut 1993; 34: (8) 1123

Chariot P, Monnet I, Gherardi R. Hop Henri Mondor, Dept Pathol, Div Neuropathol, F-94010 Creteil, France. Cytochrome C oxidase reaction improves histopathological assessment of zidovudine myopathy. Ann Neurol 1993; 34: (4) 561

Chaulet P. CHU Alger Ouest, Hop Beni Messous, Clin Pneumo- phtisiol Matiben, Algiers, Algeria. The supply of antituberculosis drugs and national drug policies (Reply). Tubercle Lung Dis 1993; 7 4 (5) 346

Craig TJ, Davis W. Charleston Naval Hosp, Charleston, SC 29408, USA. Hepatitis associated with high dose intravenous y-globulin (Letter). Ann Allergy 1993; 71: (3) 276

Dan M, Feigl D. E Wolfson Hosp, Infect Dis Unit, IL-58100 Holon, Israel. Erythromycin-associated hypotension (Brief Report). Pediat IMDis J 1993; 12: (8) 692

Davila I, Diez ML, Quirce S, Fraj J, De la Hoz B, Lazar0 M. Hosp Ramon y Cajal, Sew Alergia, Ctra Colmenar Viejo Km 9100, E- 28034 Madrid, Spain. Cross-reactivity between quinolones - Report of three cases. Allergy 1993; 48: (5) 388

Davoren P, Mainstone K. Gold Coast Hosp, 108 Nerang St, South- port, Qld 421 5, Australia. Norfloxacin-induced hepatitis (Letter). Med JAusfralia 1993; 159 (6) 423

De Francisco A, Chakraborty J, Chowdhury HR, Yunus M, Baqui AH, Siddique AK, Sack RB. Int Ctr Diarrhoel Dis Res, GPO Box 128, Dhaka IOOO, Bangladesh. Acute toxicity of vitamin A given with vaccines in infancy. Lancet 1993; 342: (8870) 526

De Jong TPVM, Doncker-Wolcke RAMG, Boemers TM. Univ Hosp Children & Youth, Ctr Pediat Renal, Utrecht, The Netherlands. Neomycin toxicity in bladder irrigation. J Urol 1993; 150: (4) 1 I99

Duclos P, Pless R, Koch J, Hardy M. Lab Ctr Dis Control, Bur Com- municable Dis Epidemiol, Div Childhood Immuniz, Ottawa, On- tario, Canada KIA OL2. Adverse events temporally associated with immunizing agents. Can Fam Phys 1993; 39: 1907

Durosinmi MA, Ajayi AA. Abafemi Awolowo Univ, Dept Haematol & Immunol, Ife, Nigeria. A prospective study of chloramphenicol- induced aplastic anaemia in Nigerians. Trop Geogr Med 1993; 4 5 (4) 159

Dyer C. Address not available. Widow given aid to sue over use of zidovudine (News). Brit Med J 1993; 307: (6905) 644

Ewig S, Rockstroh JK, Seitz HM, Marklein G, Christ F, Luchters G, Brackmann HH, Luderitz B. Univ Bonn, Med Klin, Sigmund Freud Str 25, D-53127 Bonn 1, FRG. Pneumocystis carinii infections in HIV-infected hemophiliacs during aerosolized pentamidine prophylaxis. Respiration 1993; 60: (3) 186

F e r n s VJ, Hall RJ, McAllister HA*. "Lukes Episcopal Hosp, Dept Pathol, 6720 Bertner, MC 1-102, Houston, Tx 77030, USA. Chlo- roquine-induced cardiomyopathy. Circufation 1993; 88: (2) 785

Flisser A, Madrazo I, Plancarte A, Schantz P, Allan J, Craig P, Sarti E. UNAM, Fac Med, Mexico City, DF, Mexico. Neurological symptoms in occult neurocysticercosis after single taeniacidal dose of praziquantel. Lancet 1993; 342 (8873) 748

Fombeur JP, Barrault S, Koubbi G, Laurier JN, Ebbo D, Lecomte F, Sorrel N, Dobler S. Hop St Michel, Serv ORL & Chirurg Cervico Faciale, 33 rue Olivier de Serres, Paris, France. Study of the efficacy and safety of ciprofloxacin in the treatment of chronic sinusi- tis (French, English Abstract). Med MaI Infec 1993; 23: (Spec issue) 21

Fombeur JP, Barrault S, Koubbi G, Laurier JN, E b b D, Lecomte F, Sorrel N, Dobler S. Hop St Michel, Serv ORL & Chirurg Cervico Faciale, 33 rue Olivier de Serres, Paris, France. Study of the efficacy and safety of ciprofloxacin in the treatment of chronic otitis (French, English Abstract). Med Ma1 Infec 1993; 23: (Spec issue) 26

Forsen KO, Wikberg R, Lehtonen L*. 'Orion Farmos Pharmaceut, Res Ctr, POB 65, SF-02101 Espoo, Finland. Efficacy and tolerance

of erythromycin acistrate in the treatment of acute exacerbations of chronic bronchitis in the elderly. Chemotheram 1993; 3 9 (6) 443

Friese K. Univ Heidelberg, Klin Med Mannheim, Fak Frauenklin, Theodor KutLer Ufer, D-68167 Mannheim, FRG. Theraov with antibiotics in pregnancy (German, English Abstract). Immun fnfeek 1993; 21: (4) 11 1

Funai N, Shimamoto Y, Matsuzaki M, Watanabe M, Tokioka T, Sueoka E, Suga K, Ono K, Sano M, Yamaguchi M. Saga Med Sch, Dept Internal Med, Div Haematol, Nabeshima, Saga 849, Ja- pan. Hyperkalaemia with renal tubular dysfunction by sulfamethoxazole-trimethoprim for Pneumocystis curinii pneumonia in patients with lymphoid malignancy. Haernatologia 1993; 2 5 (2) 137

Galofre N, Goday A, Knobel H, Minguez S. Hosp Esperam, Serv Med Interna, Barcelona, Spain. Diabetes mellihu induced by pentamidine (Letter) (Spanish, English Abstract). Rev Clin Espan 1993; 193: (3) 150

Gamelli RL, Paxton TP, OReilly M Loyola Univ, Med Ctr, Inst Shock Trauma, 2160 Sth 1st Ave, Bldg 54, Rm 260, Maywood, 11 60153, USA. Bone marrow toxicity by silver sulfadiazine. Surg Gynecol Obstet 1993; 177: (2) 115

Gendeh BS, Said H, Gibb AG, Aziz NS, Kong N, Zahir ZM. Nth Riding Infirm, Dept ENT, Newport Rd, Middlesborough TSJ SJE, England. Gentamicin ototoxicity in continuous ambulatory perito- neal dialysis. JLavngol Otol 1993; 107: (8) 681

Georgetson MJ, Y a m JC, Lalos AT, Webster GF, Martin P. Guthrie Clin, Dept Gastroenterol & Hepat, GI Sect, Sayre, Pa 18840, USA. Exacerbation of psoriasis due to interferona treatment of chronic active hepatitis (Case Report). Amer J Gmfroenterol 1993; 88: (10) 1756

Ghiupure V, O'Connell B, Schiffer CA. Univ Maryland, Sch Med, Baltimore, Md 21201, USA. Malocillin-induced thrombocytopenia (Letter). A n n Intern Med 1993; 119 (8) 862

Gnam W, Flint A, Goldbloom D. Toronto Hosp, Dept Psychiat, Gen Div, Toronto, Ontario, Canada. Isonazid-induced hallucinosis: Re- sponse to pyridoxine. Psychosomatics 1993; 3 4 (6) 537

Goetz MB, Sayers J. Vet Adm Med Ctr, Dept Med, Infect Dis Sect, Sepulveda, Ca 91343, USA. Nephrotoxicity of vancomycin and aminoglycoside therapy separately and in combination. J Antimi- crob Chemorher 1993; 32: (2) 325

Gokhale PC, Barapatre RJ, Advani SH, Kshirsagar NA*, Pandya SK. *Seth GS Med Coll, Dept Pharmacol, Bombay 400012, India. Pharmacokinetics and tolerance of liposomal amphotericin B in patients. JAnrimicrob Chemother 1993; 32: (1) 133

Govaert TME, Dinant GI, Area K, Masurel N, Sprenger MJW, Knottnerus JA. Mauritsweg 3, 6171 RM Stein, The Netherlands. Adverse reactions to influenza vaccine in elderly people: Random- ised double-blind placebo-controlled trial. Brit Med J 1993; 307: (6910) 988

Greenberg S, Reiser IW*, Chou SY. *Brookdale Hosp Med Ctr, Div Nephrol & Hypertens, Brooklyn, NY 11212, USA. Hyperkalemia with high-dose trimethoprim-sulfamethoxazole therapy (Case Re- port). Amer J Kidney Dis 1993; 22: (4) 603

Grosset J. Grp Hosp Pitie Salpetriere, Cent Bacteriol Virol Lab, 47 Blvd Hop, F-75634 Paris 13, France. The protection of non-tuberculous children against anti-tuberculosis drugs in developing countries (Reply). Tubercle Lung Dis 1993; 7 4 (5) 348

Grzbowski S. Univ British Columbia, Vancouver Gen Hosp, Div Resp, 2775 Heather St, Vancouver, Brit Columbia, Canada V5Z 355. The supply of antituberculosis drugs and national drug policies (Letter). Tubercle Lung Dis 1993; 7 4 ( 5 ) 346

Haddad M, Shabat S, Koren A, Stelman E, Zelikovski A. Tel Aviv Univ, Sackler Med Ctr, Vasc Surg Unit, IL-49100 Petah Tiqwa, Israel. Fusidic acid induced jaundice (Letter). fiur J Clin Microbiol Infect Dis 1993; 12: (9) 725

Halpern M, Meyers B, Miller C, Bodenheimer H, Thung SN, Adler J, Toth D, Cohen D, Boccardo L, DiFerdinando G et ul. Mt Sinai Med Ctr, New York, NY 10029, USA. Severe isoniazid-associated

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hepatitis - New York, 1991-1993 (Reprinted from MMWR 1993, 42 545). J Am Med Assn 1993; 270 (7) 809

Hann SK, Kim JB, Im S, Han KH, Park YK. Yonsei Univ, Coll Med, Dept Dermatol, CPO Box 8044, Seoul, South Korea. Itraconazole- induced acute hepatitis (Letter). Brit J Dennatol 1993; 129 (4) 500

Harb GE, Alldredge BK, Coleman R, Jacobson MA*. *San Francisco Gen Hosp, Med Serv, 995, Potrero Ave, San Francisco, Ca 94100, USA. Pharmacoepidemiology of adverse drug reactions in hospital- ized patients with human immunodeficiency virus disease. J Acq Immw DeJic Syndrome 1993; 6 (8) 919

Hare1 Y, Scott WA, Szeinberg A, Baailay Z. Univ Texas, SW Med Ctr, Childrens Med Ctr Dallas, Pediat Intens Care Unit, Dallas, Tx 75235, USA. Pentamidine-induced tonades de pointes (Brief Re- port). f ediar Inf Dis J 1993; 12: (8) 692

Harun M. St Carolus Hlth Serv, Jakarta 1044, Indonesia. The proteo- tion of non-tuberculous children against anti-tuberculosis drugs in developing countries (Letter). Tubercle Lung Dis 1993; 7 4 (5) 347

Hebert MF, Roberts JP. Univ Calif San Francisco, Div Clin Pharm, Rm C152, Box 0622, San Francisco, Ca 94143, USA. Endstage liver disease associated with nitrofurantoin requiring liver transplantation. Ann Phannacother 1993; 27: (10) 1193

Heikkila AM. Turku Univ, Cent Hosp, Dept Obstet & Gynecol, Kii- namyllynkatu 4-8, SF-20520 Turku 52, Finland. Antibiotics in pregnancy. A prospective cohort study on the policy of antibiotic prescription. Ann Med 1993; 2 5 (5) 467

Hepbum NC, Siddique I, Howie AF, Beckett GJ, Hayes PC. Royal Edinburgh & Associated Hosp, Dept Dermatol, Edinburgh EH3 9YW, Scotland. Hepatotoxicity of sodium stibogluconate in leish- maniasis (Letter). Lancet 1993; 342 (8865) 238

Hui CH, Chan LS. Univ Hong Kong, Queen Mary Hosp, Hong Kong, Hong Kong. Agranulocytosis associated with cephalosporin. Brit MedJ 1993; 307: (6902) 484

Humphreys JE, Smith EG, Coles SJ. Abbott Labs, Dept Med, Maid- enhead SL6 4XE, Berks, England. A clarithromycin sensitivity survey in the United Kingdom using Stokes' method (Letter). J An- timicrob Chemother 1993; 32: (2) 341

Isaacson SH, Carr J, Rowan AJ*. *Vet A h Med Ctr, Neurol Serv 127, 130 West Kingsbridge Rd, Bronx, NY 10468, USA. Ciprofloxacin-induced complex partial status epilepticus manifest- ing as an acute confusional state. Neurology 1993; 43: (8) 1619

Jick SS, Jick H, Dean AD. Boston Univ, Med Ctr, Boston Collaborat Drug Surveillance Program, 11 Muzzey St, Lexington, Ma 02173, USA. A follow-up safety study of ciprofloxacin users. fhanna- cotherqy 1993; 1 3 (5 ) 461

Kamikubo K, Takami R, Suwa T, Kawase Y, Shiroko J, Kametani M, Tokimitsu N, Sakata S. Takayama Red Cross Hosp, Dept Internal Med, 3-1 1 Tenmancho, Takayama 506, Japan. Silent thyroiditis de- veloped during a-interferon therapy. Amer J Med Sci 1993; 306: (3) 174

Karbwang J, Bangchang KN, Bunnag D, Harinasuta T, Laothavorn P. Mahidol Univ, Dept Clin Trop Med, Clin Phamacol Unit, Bang- kok 10400, Thailand. Cardiac effect of halofantrine (Letter). fan- cet 1993; 342: (8869) 501

Kennedy CA, Pimentel JA, Lewis DE, Anderson MD, Weiss PJ, Old- field EC. USN Hosp, Dept Clin Invest, San Diego, Ca 92134, USA. Crossover of human immunodeficiency virus-infected patients from aerosolized pentamidine to trimethorpim-sulfamethoxazole - Lack of hematologic toxicity and relationship of side effects to CD4+ lymphocyte count. JInfec Dis 1993; 168. (2) 314

Kobashigawa JA, Warner-Stevenson L, Johnson BL, Moriguchi JD, Kawata N, Drinkwater DC, Laks H. Univ Calif Los Angeles, Med Ctr, Ctr Hlth Sci, 47 123, Los Angeles, Ca 90024, USA. Influenza vaccine does not cause rejection after cardiac transplantation. Transplant froc 1993; 2 5 (4) 2738

Kumar H, Ahuja S, Kumar A*. *All India Med Sci, Rajendra Prasad Ctr Ophthalm Sci, New Delhi 110029, India. Macular infarction

after intravitreal amikacin. Ann Ophthalmot 1993; 2 5 (7) 262 Kurowski V, Fink C, Schwieder G, Djonlagic H. Univ Lubeck, Innere

Med Klin, Ratzburger Allee 160, D23538 Lubeck, FRG. Cardiac arrhythmia in rapid central venous administration of cefotaxime (Letter) (German, English Abstract). Deur Med Wochenschr 1993; 118: (41) 1502

Land G, Salgado J, Greenberg RN. Univ Kentucky, Med Ctr, Dept Med, 800 Rose St, Lexington, Ky 40536, USA. Onset of lifethreatening ventriculitis during ceftazidine therapy for nosocomial pneumonia due to Enterobacter cloacae (Letter). CIin Infect Dis 1993; 17: (2) 295

Lanoux P, Legin C, Reksa A, Penalba C. Hop Corvisart, Ctr Hosp Charleville Mezieres, Serv Med Interne A, 28 rue Aubilly, F- 08011 Charleville Mezie, France. Retrospective study of adverse effects of the fluoroquinolones: Results on one year (Letter). Med Mat Infec 1993; 23: (8-9) 631

Layton AM, Cunliffe WJ. Gen Infirm, Dept Dermatol, Great George St, Leeds LSI 3EX, England. Phototoxic eruptions due to doxycy- cline - A doserelated phenomenon. CIin Exp Dermatol 1993; 1 8 ( 5 ) 425

Levy JH, Mar@ AT. Emory Univ, Sch Med, Emory Clin, Div Cardiothorac Anesthesiol & Crit Care, Atlanta, Ga 30322, USA. Vancomycin and adverse drug reactions (Editorial). Crit Care Med 1993; 21: (8) 1107

Lien YHH, Hansen R, Kern WF, Bangert J, Nagle RB, KO M, Siskind MS. Univ Arizona, Hlth Sci Ctr, Dept Med, Renal Sect, Tucson, Az 85724, USA. Ciprofloxacin-induced granulomatous interstitial nephritis and localized elastolysis (Case Report). Amer J Kidney Dis 1993; 22: (4) 598

Lifermann F, Lemetayer P, Beylot J, Sebban A, Lacost D, Doutre MS. Hop St Andre, Serv Med Interne, F-33076 Bordeaux, France. Stunned myocardium during treatment with pentamidine isethionate (French, English Abstract). Ann Med Intern 1993; 144: (5) 343

Limburg PJ, Katz H, Grant CS, Service FJ*. *Mayo Clin & Mayo Grad Sch Med, 200 1st St SW, Rochester, Mn 55905, USA. Qui- nine-induced hypoglycemia. Ann Intern Med 1993; 119 (2) 218

Maguire RB, Stroncek DF*, Campbell AC. 'Univ Minnesota Hosp & Clin, Dept Cardiovasc Sci, Blood Bank Lab, Box 198, UMHC D2ll Mayo, Minneapolis, Mn 55455, USA. Recurrent pancytopenia, coagulopathy, and renal failure associated with multiple quinine-dependent antibodies. Ann Intern Med 1993; 119 (2) 215

Magulike NO, Ihenacho HNC, Ike VO. Univ Nigeria, Teaching Hosp, Dept Ophthalmol, PMB 01 129, Enugu, Nigeria. Chloroquine retinopathy in Nigerian patients with heart block. Eye 1993; 7: (4) 591

Mansoor GA, Panner BJ, Omt DB. Univ Rochester, Rochester, NY 14642, USA. Azithromycin-induced acute interstitial nephritis (Letter). Ann Intern Med 1993; 119 (7 Pt 1) 636

Marsepoil T, Petithory J, Faucher JM, Ho P, Viriot E, Benaiche F. CMC E-Rain, Serv Reanimat, 25 rue P de Theilley, F-95500 Gon- esse, France. Encephalopathy and amnesia following mefloquine therapy (French, English Abstract). Rev Med Interne 1993; 1 4 (8) 788

Mathelier-Fusade P, Leynadier F. Hop Rothschild, Ctr Allergie, Sew Med Interne, 33 Blvd Picpus, F-75571 Paris 12, France. Intoler- ance to sulfonamides in HIV-infected subjects: Toxic and allergic drugs (French, English Abstract). Presse Medicate 1993; 2 2 (29) 1363

McCarthy AE, Keystone JS, Kain KC*. *Toronto Hosp, Trop Dis Unit, 200 Elizabeth St, EN G-224, Toronto, Ontario, Canada M5G 2C4. Pancreatitis occurring during therapy with stibogluconate Two case reports. Clin Infect Dis 1993; 17: ( 5 ) 952

McCarthy M. Address not available. Adverse events and childhood vaccines (News). Lancer 1993; 342: (8874) 798

McLoon LK, Wirtschakr JD, Cameron JD. Univ Minnesota, Dept Ophthalmol, Box 493 UMHC, Minneapolis, Mn 55455, USA. Muscle loss from doxorubicin injections into the eyelids of a patient with blepharospasm (Letter). Amer J Ophrhdmol 1993; 116 (5) 646


Mevorach D, Lossos IS, Oren R. Hadassah Univ Hosp, Dept Med, Mt Scopus, FQB 24035, Jerusalem, Israel, Cefuroxime-induced fever. Ann Pbarmacother 1993; 27: (7-8) 881

Miller HC. Childrens Hosp Med Ctr, Div Emergency Med, ASB 4, Elland & Bethesda Ave, Cincinnati, Oh 45229, USA. Cardiac arrest atter intravenous pentamidine in an infant (Brief Report). Pediat lnf Dis J 1993; 12 (8) 694

Mitoro A, Yoshikawa M, Yamamoto K, Mimura M, Yoshikawa Y, Shiroi A, Mochi T, Sakamoto T, Yamao J, Kikuchi E et al. Hattori Mem Hosp, Dept Gastroenterol, 4244 Kanmaki, Kanmaki cho, Nara 63902, Japan. Exacerbation of ulcerative colitis during a-interferon therapy for chronic hepatitis C. Internal Med 1993; 32: (4) 327

Miyahara H, Koga T, Imayama S, Hori Y. Kyushu Univ, Fac Med, Dept Dermatol, Maidashi 3-1-1, Higashi ku, Fukuoka 812, Japan. Occupational contact urticaria syndrome from cefotiam hydrochlc- ride. Contact Dermatitis 1993; 2 9 (4) 210

Moms JT, Kelly JW. Brooke Army Med Ctr, Ft Sam Houston, Tx 78234, USA. Rifabutin-induced ageusia (Letter). Ann Intern Med 1993; 119 (2) 171

Morton CA, Evans CD, Douglas WS. Monklands Dist Gen Hosp, Dept Dermatol, Airdrie ML6 OJS, Scotland. Allergic contact dermatitis following subconjunctional injection of framycetin. Contact Demafids 1993; 2 9 (1) 42

Moskowitz Y, Leibowitz E, Ronen M, Aviel E. Barzilai Govt Hosp, Dept Ophthalmol, Ashqelon, Israel. Pseudotumor cerebri induced by vitamin A combined with minocycline. Ann Ophthalmol 1993;

Mulholland EK, Ahonkhai VI, Greenwood AM, Jonas LC, Lukacs W, Mink CM, Staub JM, Todd J, Vella PP, Greenwood BM. MRC Labs, POB 273, Banjul, Senegambia. Safety and immunogenicity of Haemophilus influenrue type BINeisseria meningitidis group B outer membrane protein complex conjugate vaccine mixed in the syringe with diphtheria-tetanus-pertussis vaccine in young Gam- bian infants. Pediar Inf Dis J 1993; 1 2 (8) 632

Nielsen TL, Jensen BN, Nelsing S, Pedersen C, Mathiesen LR, Skin- hoj P, Nielsen JO. Hvidovre Univ Hosp, Infekt Med Afdeling 144, DK-2650 Hvidovre, Denmark. Prevention of Pneumocystis carinii pneumonia relapse in AIDS patients - The efficacy and tolerability of low-dose sulfamethoxazole-trimethoprim. Dan Med Bull 1993; 4 0 (4) 503

Nunn P, Porter J, Winstanley P. WHO, TUB, CDS, 20 Ave Appia, CH-1211 Geneva 27, Swimrland. Thiacetazone: Avoid like poison or use with care? Trans Roy Soc Trop Med Hyg 1993; 87: (5) 578

Oeda E, Shinohara K. Yamaguchi Prefecture Cent Hosp, Dept Med, Div Hematol, Hofi 747, Japan. Cutaneous necrosis caused by injection of a-interferon in a patient with chronic myelogeneous leukemia (Letter). Arner J Hematof 1993; 44: (3) 21 3

Oleaga JM, Aguirre A, Gonzalez M, Diaz-Perez JL. Cruces Hosp, Dept Dermatol, PI Cruces S-N, Vizcaya, Spain. Topical provoca- tion of fixed drug eruption due to sulphamethoxazole. Contact Dermatitis 1993; 29: (3) 155

Orenstein DM, Pattishall EN, Noyes BE, Kurland G, Hartigan ER, Yu VL. Childrens Hosp Pittsburgh, Dept Pediat, 3705 5th Ave, Pittsburgh, Pa 15213, USA. Safety of ciprofloxacin in children with cystic fibrosis. Clin Pediat 1993; 32: (8) 504

Ozen H, Secmeer G, Kanra G, Ceyhan M, Kurucu N. Hacettepe Univ, Fac Child Hlth, Ankara, Turkey. Cardmc arrest - An unusual side effect of intravenous ornidazole. Turk J Pediat? 1993; 35 (1) 65

Pames LS, Riddell D. Univ Western Ontario, Univ Hosp, Dept Oto- laryngol, 339 Windermere Rd, London, Ontario, Canada N6A 5A5. Irritative spontaneous nystagmus following intratympanic gentamicin for Meniere's disease. htyngoscope 1993; 103: (7) 745

Paulwzi P, Kokelj F, Perkan V, Povato G, Moretti M. Univ Trieste, Dept Dermatol, 1-34127 Trieste, Italy. Psoriasis exacerbation induced by interferon-a report of 2 cases. Acta Dermato-Venereol

25: (8) 306

1993; 73: (5) 395 Pellicano R, Iannantuono M, Lomuto M. Casa Sollievo Sofferenza

Hosp, IRCCS, Dept Dermatol, 1-71013 San Giovanni Roto, Italy. Pemphigus erythematosus induced by ceftazidine. Int J Dematol 1993; 32 (9) 675

Piper JM, Mitchel EF, Ray WA. Vanderbilt Univ, Dept Prevent Med, Med Ctr N A-1 112, Nashville, Tn 37232, USA. Prenatal use of metronidazole and birth defects - No association. Obstet Gynecol 1993; 82: (3) 348

Pirker C, Moslinger T, Wantke F, Gotz M, Jarisch R. Dermatol & Pediat Allergy Clin, Franz Jonas PI 8-6, A-1210 Vienna, Austria. Ethylmercuric chloride - The responsible agent in thimerosal hypersensitivity. Contact Dennarids 1993; 2 9 ( 3 ) 152

Plantin P, Mahe M, Lenoach E, Leroy JP. Ctr Hosp Inter Communal Cornouaille, Serv Dermatol, F-29107 Quimper, France. Cutaneous necrosis following subcutaneous injections of amikacin (Letter) (French, English Abstract). Presse Medicale 1993; 22: (29) 1366

Poitrineau Y, Barthelemy I, Rouby D, Fauron P, Barrau P, Beligon C. Ctr Hosp Gen, Samu 03, F-03006 Moulins, France. Fatal poisoning by rifampicin - A case report (French, English Abstract). Therape 1993; 48: (3) 271

Ramsay B, Woodrow D, Cream JJ. Charing Cross Hosp, Dept Dex- matol, London W6 8RF, England. An acantholytic bullous eruption after nofloxacin (Letter). Brit J Dermafol 1993; 129 (4) 500

Roberrs GW, Nation RL, Jarvinen AO, Martin AJ. Adelaide Child- Tens Hosp Inc, Dept Pharm, Adelaide, SA SIX%, Australia. An in vivo assessment of the tobramycin-ticarcillin interaction in cystic fibrosis patients. Brit J Clin Pbarmacoll993; 36 (4) 372

Rollof J, Vinge El. *Lund Univ Hosp, Dept Clin Pharmacol, S-22185 Lund, Sweden. Neurologic adverse effects during concomitant treatment with ciprofloxacin, NSAIDs, and chloroquine: Possible drug interaction. Ann Pharmacother 1993; 27: (9) 1058

Rombo L, Angel VH, Firman G, Hellgren U, Mittelholzer ML, Stur- chler D. Huddinge Univ Hosp, Box 5651, S-14186 Huddinge, Sweden. Comparative tolerability and kinetics during long-term intake of LariamB and Fansidam for malaria prophylaxis in nonim- mune volunteers. Trop Med Parmito1 1993; 44: (3) 254

Rousseau MC, Disdier P, Verrot D, Hark JR, Horschowski N, Weiller PJ. Hop La Timone, Serv Med Interne, F-13385 Marseille 5, France. Tuberculosis pleuritis during treatment with a-interferon in a patient with hairy cell leukemia (French, English Abstract). Rev Med Interne 1993; 14: (7) 745

Schmidt S, Cordt-Schlegel A, Heitmann R. RLK Bonn, Neurol Abt, Kaiser Karl Ring 20, D-53 11 1 Bonn, FRG. Guillain-Bam syndrome during treatment with ofloxacin (Letter). J Neurol 1993; 240 (8) 506

Sedlmayr T, Peters F, Raasch W, Kees F. Univ Mainz, Akad Lehr- krankenhaus, St Hildegardis Krankenhaus, Frauenklin, Hildegardstr 2, D-55131 Mainz, FRG. Clarithromycin - Pharmacokinetics, clinical effectiveness transmission into breast milk of a new macrolide antibiotic in patients with puerperal infections (German, English Abstract). Geburtsh Frauenheilk 1993; 53: (7) 488

Segars LW, Threlkeld KR. SW Oklahoma State Univ, Coll Pharm, Dept Clin Pharm, 1000 N Lee St, POB 205 SWOSU, Oklahoma City, Ok 73101, USA. Clindamycin-induced lip and nasal passage swelling. Ann Pharmacother 1993; 27: (7-8) 885

Sekas G, Paul HS. Univ Pittsburgh, Sch Med, Pittsburgh, Pa 15261, USA. Hypenunmonemia and camitine deficiency in a patient receiving sufadiazine and pyrimethamine. Arner J Med 1993; % ( I ) 112

Sheela A, Thachil RT*, Sridhar CB. *St Johns Med Coll Hosp, Dept Med, Bangalore 560034, Karnataka, India. Dapsone poisoning. J Trop Med h'yg 1993; 9 6 (5) 274

Sherernata WA, Benedict D, Squilacote DC, Sazant A, De Freitas E. Univ Miami, Sch Med, Ctr Multiple Sclerosis, Dept Neurol, Mi- ami, FI 33136, USA. High-dose zidovudine induction in HTLV-I associated myelopathy: Safety and possible efficacy. Neurology

CURRENT AWARENESS IN PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 53 1

1993; 43: (10) 2125 Siegmund JB, Tarshis AM, Good Samaritan Hosp, 375 Dimyth Ave,

Cincinnati, Oh 45220, USA. Prolonged jaundice after dicloxacillin therapy (Letter). Amer J Gmtroenterol 1993; 88: ( 8 ) 1299

Smythe WR, Bavaria JE. Hosp Univ Penn, Sch Med, Dept Gen Surg, Philadelphia, Pa 19104, USA. Tetracycline pleurodesis: Associated acute renal failure. Chesr 1993; 104: (4) 1274

Soto J, Bosch JM, Ortiz MA', Moreno MI, Gonzalez JD, Diaz JM. *C Floranes 48 10D, E-39010 Santander, Spain. Piperacillin-induced acute interstitial nephritis (Letter). Nephron 1993; 65: (1) IS4

Sowunmi A, Salako LA, Oduola AMJ, Walker 0, Akindele JA, Ogundahunsi OAT. Univ Coll Hosp Ibadan, Clin Phamacol Unit, Ibadan, Nigeria. Neuropsychiatric side effects of mefloquine in Af- ricans. Trans Roy Soc Trop Med Hyg 1993; 87: (4) 462

Stavola JJ, Noel GJ, Cornell Univ, Med Ctr, New York Hosp, Coll Med, Div Pediat Infect Dis & Immunol, 525 E 68th St, New York, NY 10021, USA. Efficacy and safety of dapsone prophylaxis against P n e m q s r i s carinii pneumonia in human immunodeficiency virus infected children. Pediat InfDis J 1993; I 2 (8) 644

Stramba-Badiale M, Guffanti S, Porta N, Frediani M, Beria G, Col- naghi C. Univ Milan, 1st Clin Med 2, via F Sforza 35, 1-20122 Milan, Italy. QT interval prolongation and cardiac arrest during antibiotic therapy with spiramycin in a newborn infant. Amer H e m J 1993; 126: (3) 740

Sunderkotter C, Luger T, Kolde G. Univ Munster, Dept Dermatol, D-48149 Munster, FRG. Severe hypertriglyceridaemia and interferon-a (Letter). Lancer 1993; 342: (8879) I 1 1 I

Szof C, Walker PC. Childrens Hosp Michigan, Ctr Drugs Informat, 3901 Beaubien Blvd, Detroit, Mi 48201, USA. Incompatibility of cefotaxime sodium and vancomycin sulfate during Y-site administration (Letter). Amer J Hosp Phann 1993; 50: (10) 2054

Tal A, Dall L. Univ Missouri, Sch Med, Kansas City, Mo 64108, USA. Didanosine-induced hypertriglyceridernia. Amer J Med 1993; 95: (2) 247

Teh C, McKendrick M. Royal Hallamshire Hosp, Dept Infect Dis & Med, Sheffield SIO 2JF, England. Ciprofloxacin-induced thrombocytopenia. JInfecfion 1993; 27: (2) 213

Terol MJ, Sierra J, Gatell JM, Roman C. Hosp Clin Barcelona, Dept Hematol, Villarroel 170, E-08036 Barcelona, Spain. Thrombocy- topenia due to use of teicoplanin (Letter). Clin Infecr Dis 1993; 17: (5) 927

Thijs JC, Van Zwet AA, Oey HB. Bethesda Hosp, Dept Internal Med, Dr GH Amshoffweg 1, 7909 AA Hoogovens, The Netherlands. Ef- ficacy and side effects of a triple drug regimen for the eradication of Heficobacter wfori. &and J Gasfroenterof 1993; 28: (1 1 ) 934

Tissing WJE, Umans-Eckenhausen MAW, Van den Anker JN. Eras- mus Univ Rotterdam, Dept Paediat, Div Neonatal, Gordelweg 160, 3038 GE Rotterdam, The Netherlands. Vancomycin intoxication in a preterm neonate (Letter). Ew J Pediar 1993; 152: ( 8 ) 700

Tjonck JR, Willems FTC. Medical Ctr de Klokkenberg, Galderseweg 81,4836 AE Breda, The Netherlands. Ofloxacin in the treatment of acute exacerbations of chronic bronchitis - Efficacy and safety of a once-daily regimen. Cum 7'her Res 1993; 54: (3) 265

Tomomasa T, Miyazaki M, Koizumi T, Koroume T. Gunrna Univ, Sch Med, Dept Pediat, 3-39-15 Schowa machi, Maebashi, Gunrna 371, Japan. Erythromycin increases gaSeic antral motility in human premature infants. Biol Neonate 1993; 63: (6) 349

Tomegrosa JV, Campistol JM, Franco A, Andreau J. Univ Barcelona, Hosp Clin, Renal Transplant Unit, Villarroel 170, E-08036 Bar- celona, Spain. Interaction of josamycin with cyclosporin A (Let- ter). Nephron 1993; 65: (3) 476

Trifillis AL, Cui X, Drusano GL. Univ Maryland, Sch Med, Dept Pathol, Baltimore, Md 21201, USA. Use of human renal proximal tubule cell cultures for studying foscmet-induced nephrotoxicity in vitro. Antimimob Agents Chemother 1993; 37: (1 I ) 24%

Tsuda S, Kato K, Karashima T, Inou YH, Sasai Y. Kurume Univ, Sch Med, Dept Dermatol, 67 Asahi machi, Kurume, Fukuoka 830,

Japan. Toxic pustuloderma induced by ofloxacin. Acra Dermato- Venereol 1993; 73: (5) 382

Vadheim CM, Greenberg DP, Partridge S, Jing J, Ward JI, Marcy SM, Gates J, Steinberg E, Ackerson B, Wong V er al. UCLA, Harbor Med Ctr, Ctr Vaccine Res, 1124 W Carson St E-6, Tor- rance, Ca 90502, USA. Effectiveness and safely of an Haemophi- fur infruenzae type b conjugate vaccine (PRP-T) in young infants. Pediatrics 1993; 92: (2) 272

Valsecchi R, Pansera B, Di Landro A, Cainelli T. Osped Riuniti Ber- gamo, Dept Dermatol, 1-24100 Bergamo, Italy. Contact dermatitis from ketoconazole. Contact Dermatitis 1993; 29: (3) 162

Van Brake1 WH, Drever W. MF LCP, POB 5, Pokhara, Nepal. Side effects of isoprodian compared with WHO-MDT in rural Nepal. Leprosy Rev 1993; 64: (3) 276

Verma L, Arora R, Sachdev MS. 4654 Shora Kothi, Pahar Ganj, New Delhi 110055, India. Macular infarction after intravitreal injection of amikacin. Can J Ophrhal-J Can Ophrhar 1993; 28: (5) 241

Vincken W, Yernault JC. Vrije Univ Brussels, AZ, Dept Pneumol, Laarbeeklaan 101, B-1090 Brussels, Belgium. Efficacy and tolerability of clarithromycin versus azithromycin in the short course @eatment of acute bronchitis. Drug Invesr 1993; 6 (3) 170

Weinberg WG. SE Permanente Med Grp, Infect Dis Sew, Cumber- land Med Off, 2525 Cumberland P k w , Atlanta, Ga 30339, USA. Safety and efficacy of teicoplanin for bone and joint infections - Results of a community-based trial. Southern MedJ 1993; 86: (8) 89 1

Weinroth SE, Tuazon CU. George Washington Univ, Med Ctr, Wash- ington, DC 20037, USA. Alopecia associated with fluconazole treatment (Letter). Ann Inrern Med 1993; 119: (7 Pt 1) 637

Wen ZM, Ye ST. Beijing Union Med Coll Hosp, Dept Allergy, mi- jing 100730, Peoples Rep China. Skin testing in patients with high risk of anaphylactic reactions to penicillin. Asian Pac J Allergy Imrnunof 1993; 11: (1) 13

Wilkinson R, Mahatane J, Wade P, Pasvol G. Northwick Pk Hosp & Clin Res Ctr, St Marys Hosp Med Sch, Dept Infect & Trop Med, Harrow HA1 3UJ, Middx, England. Chloroquine poisoning (Let- ter). Brit MedJ 1993; 307: (6902) 504

Xarau SN, Trias PN, Cedeno VI. Hosp Clin Barcelona, Area Vigilan- cia Intens, Barcelona 36, Spain. Extrarenal depuration in poisoning by isoniazide (Letter) (Spanish, English Abstract). Med CIin 1993; 101: (7) 277

Yew WW, Wong CF, Wong PC, Lee J, Chau CH. Grantham Hosp, TB & Chest Unit, 125 Wong Chuk Hang Rd, Aberdeen, Hong Kong. Adverse neurological reactions in patients with multidrug- resistant pulmonary tuberculosis after coadministration of cycloser- ine and ofloxacin (Letter). Cfin Infect Dis 1993; 17: (2) 288

Zacharia PT, Deppermann SR, Schuman JS*. *Tufts Univ, Sch Med, New England Eye Ctr, 750 Washington St, Box 450, Boston, Ma 02111, USA. Ocular hypotony after trabeculectomy with mitomycin C. AmerJOphrhafmol 1993; 1 1 6 (3) 314

1.1\. 4 CARDIOVASCULAR SYSTEM AGENTS

Flosequinan withdrawn (News). Lancet 1993; 342: (8865) 235 Ansoborlo P, Constans J, Lemetayer P, Conri C. Hop St Andre, Sew

Med Interne & Cardiol, I rue Jean Burguet, F-33075 Bordeaux, France. Amiodarone-induced pneumonitis in internal medicine, 8 case reports (French, English Abstract). Rev Med Interne 1993; 1 4 (7) 698

Baggio E, Gandini R, Plancher AC, Passeri M, Carmosino G. Osped Buzzi, Dipt Med Gen, via Castelvetro, 1-20154 Milan, Italy. Italian multicenter study on the safety and efficacy of coenzyme QIO as adjunctive therapy in heart failure (interim analysis). CIin Invesri- garor 1993; 71: (8 Suppl) S145

Bainbridge AD, MacFadyen RJ, Stark S, Lees KR, Reid JL. Univ Glasgow, Western Infirm, Gardiner Inst Med, Dept Med & Therapeut, Glasgow GI 1 6NT, Scotland. The antihypertensive effi-

532 CURRENT AWARENESS IN PHARMACOEPIDEMOLOGY AND DRUG SAFETY

cacy and tolerability of a low dose combination of ramipril and felodipine ER in mild to moderate essential hypertension. Erir J Clin Pharmacol 1993; 36: (4) 323

Bellou A, Henry I, Kanny G, Dekorwin JD, Moneret-Vautrin DA*. 'CHU Brabois, Serv Med D, rue Morvan, F-54511 Vandouvre Nancy, France. Present aspects in immuno-allergology of the risks involved when prescribing anti-hypertensive drugs (French, Eng- lish Abstract). Rev Fr AlZer Immunol CZin 1993; 33: (3) 241

Bewley AP, Feher MD, Staughton RCD. Westminster Med Sch & Hosp, London SWlO 9TH, England. Erythema multiforme following substitution of amlodipine for nifedipine (Drug Point). Brit Med J 1993; 307: (6898) 241

Bonner G, Lederle RM, Scholze J, Stumpe KO. Univ Cologne, Krankenhaus Koln Merheim, Innere Med Klin 2, Ostmerheimer Str 200, D-51109 Cologne, FRG. Therapeutic safety of perindopril in the treatment of mild hypertension with concomitant nephropathy. Anneim-Forsch-Drug Res 1993; 43-2: (8) 852

Bouchou K, Cathebras P, Guy C, Michel JL, Charmion S, Rousset H. CHU St Etienne, Hop Nord, Sew Med Interne, F-42055 St Etienne 2, France. Cibenzoline-induced asymptomatic hypoglycemia (Let- ter) (French, English Abstract). Rev Med Interne 1993; 14 (8) 806

Boyd I. Therapeut Goods Adm, Drug Evaluat Branch, Adverse Drug React Sect, Woden, ACT 2606, Australia. Captopril-induced taste disturbance (Letter). Lancer 1993; 342: (8866) 304

Campanacci L, Fabris B, Fischetti F, Bardelli M, Vran F, Carretta R. Univ Trieste, 1st Patol Med, Trieste, Italy. ACE inhibition in renal disease - Risks and benefits. CZin &p Hyperternion 1993; I 5 (Suppl 1) 173

Clarke WR, Horn JR, Kawabori I, Gurtel S. Childrens Hosp & Med Ctr, Dept Anesthesiol, POB C5371, CH-05 Seattle, Wa 98105, USA. Potentially serious drug interactions secondary to high dose diltiazem used in the treatment of pulmonary hypertension. Phar- macotheram 1993; 13: (4) 402

Collins P, Ferguson J. Univ Dundee, Ninewells Hosp & Med Sch, Dept Dermatol, Photobiol Unit, Dundee DDl 9SY, Scotland. Pho- todistributed nifedipine-induced facial telangiectasia. Brit J Derma- ro1 1993; 129 ( 5 ) 630

Crijns HJGM, Kingma JH, Gosselink ATM, Dalrymple HW, De Langen CDJ, Lie K. Univ Groningen Hosp, Dept Cardiol, Ctr Tho- rax, POB 30001, 9700 RE Groningen, The Netherlands. Sequential bilateral bundle branch block during dofetilide, a new class 111 antiarrhythmic agent, in a patient with atrial fibrillation. J Cardimasc Electrophysiol 1993; 4 (4) 459

Cross BW, Kirby MG, Miller S, Shah SH, Sheldon DM, Sweeney MT*. *Pfizer Ltd, Sandwich CT13 9NJ, Kent, England. A multicentre study of the safety and efficacy of amlodipine in mild to moderate hypertension. Brit J Clin Pracr 1993; 47: (5) 237

Cruikshank JM. The Bows, Wilrnslow Pk, Wilmslow SK9 2AY, Cheshire, England. Phosphodiesterase 111 inhibitors - Long-term risks and short-term benefits. Cardiovarc Drug nterqy 1993; 7: (4) 655

Cushman WC. Vet Affairs Med Ctr, Hypertens Sect 1 1 IQ, 1030 Jef- ferson Ave, Memphis, Tn 38104, USA. Systolic hypertension in the elderly - Safe treatment with low dose thiazide diuretics. Post- grad Med 1993; 9 4 (2) 143

Eber B, Tscheliessnigg KH, Anellimonti M, Kaufmann P, Lueger A, Delgado P, Kullnig P. Karl Franzens Univ, Dept Internal Med, Auenbruggerpl 15, A-8036 Graz, Austria. Aortic dissection due to discontinuation of p-blocker therapy (Case Report). Cardiology

Figueras A, Castel JM, Laporte JR, Capella D. Ciudad Sanitaria Seguridad Social Valle Hebron, Dept Fannacol Clin, P Val1 He- bron S-N, E-08035 Barcelona, Spain. Gemfibrozil-induced impo- tence (Letter). Ann Phrmacother 1993; 27: (7-8) 982

Friedland S, Kaplan S, Lahav M, Shapiro A. Beilinson Med Ctr, Dept Ophthalmol, IL-49100 Petah Tiqwa, Israel. Proptosis and periorbi- tat edema due to diltiazem treatment (Case Report). Arch Ophthal- mol 1993; 111: (8) 1027

1993; 83: (1-2) 128

Gajula RP, Berlin RM. Address not available. Captopril-induced mania (Letter). Amer J Psychiat 1993; 150: (9) 1429

Gilbert GJ. 500 Pasadena Ave, St Petersburg, FI 33707, USA. Pen- toxifylline-induced musical hallucinations. Neurology 1993; 43: (8) 1621

Gleason MM, Roloff JS, Cyran SE, Wekr HS, Baylen BG, Myers JL. Penn State Univ, Milton S Hershey Med Ctr, Childrens Hosp, Coll Med, Dept Pediat, POB 850, Hershey, Pa 17033, USA. Cap- topril-induced bone marrow suppression in 2 cardiac patients with trisomy 21. Pediar Cardiol 1993; 14 (4) 227

Goswami R, Gurtoo A. All India Inst Med Sci, Dept Endocrinol, New Delhi 1 10029, India. Hypertension and hypoparathyroidism - Nar- rowed therapeutic safety with nifedipine. Postgrad Med J 1993; 6 9 (815) 752

Grandinetti 0, Feraco E*. IINRCA, Inst Geriatr Cardiovasc Dis, Dept Cardiol, Div Cardiol, C Muoio Piccolo, 1-87100 Cosenza, Italy. Middle term evaluation of amlodipine vs nitrendipine - Efficacy, safety and metabolic effects in elderly hypertensive patients. Clin &pHyperternion 1993; 1 5 (Suppl 1) 197

Gschwantler M, Gulz W, Brownstone E, Feichtenschlager T, Pulgram T, Schrutkakolbl C, Weiss W. Krankenanstalt Rudolfstiftung Wien, Med Abt 4, Juchgasse 25, A-1030 Vienna, Austria. Digitoxin-induced thrombocytopenia - A case report. Wein KIin Wochemchr 1993; 105 (17) 500

Gwen H, Tuncok Y, Guneri S, Cavdar C, Fowler J. Dokuz Eylul Univ Hosp, Dept Pharmacol, Izrnir 35340, Turkey. Age-related digoxin-alpramlam interaction. CIin Pharmacol Ther 1993; 54: (1) 42

Hagley MT, Hulisz DT. Washington Univ, Jewish Hosp St Louis, Med Ctr, Div Cardiol Res, St Louis, Mo 63110, USA. Angioten- sin-converting enzyme inhibitor hepatotoxicity - Further insights (Reply). Ann Pharmacother 1993; 27: (9) I 142

Hess FI, Northdurft HD. Univ Munich, Dept Trop Med, D-80802 Munich, FRG. Does antiarrhythmic magnesium therapy enhance malarial infection? (Letter). Lancet 1993; 342: (8879) 1 1 13

Hilburn RB, Bookstaver D, Whitlock WL.. Dwight D Eisenhower Army Med Ctr, Dept Internal Med, Ft Gordon, Ga 30905, USA. Angiotensin-converting enzyme inhibitor hepatotoxicity - Further insights (Comment). Ann Pharmacorher 1993; 27: (9) 1142

Holzgartner H, Hoffmann J, Fuchs W, Schmidt U*. *Ameimittel Sicherheit eV, Arbeits & Forschungsgemeinschaft, Hermeskeiler Str 17, W-5000 Cologne 41, FRG. Controlled multicentre study of the antihypertensive effects and safety of delapril and enalapril alone and in combination with hydrochlorothiazide in the treatment of patients with mild to moderate essential hypertension. Acru Therap 1993; 19 (3) 241

Jain M, Armstrong L, Hall JB. Univ Chicago, Pritzker Sch Med, Dept Med, Chicago, II 60637, USA. Upper airway obstruction following angiotensin-converting enzyme inhibitor therapy (Letter). Chest 1993; 104: (4) 1311

Jamaa M, Lainecessac P*, Victor J, Tadei A, Allain P. *Ctr Hosp Reg & Univ Angers, Ctr Phannacovigilance, F-49033 Angers 01, France. Intensive survey of adverse drug reactions over 1 year in a cardiology department (French, English Abstract). nterapie 1993; 48: (3) 259

Janier M, Gerault MH, Carlotti A, Vignon MD, Daniel F. Hop St Joseph, Serv Dermatol, 191 rue Raymond Losserand, F-75674 Paris 14, France. Acute generalized exanthematous pustulosis due to diltiazem (Letter). BrirJDermatol 1993; 129 (3) 354

Kehoe RF, MacNeil DJ, Zheutlin TA, Ezri MD, Nazari J, Spangen- berg RB, Dunnington C, Lueken M. Illinois Masonic Med Ctr, Dept Clin Cardiac Electrophysiol, 836 Wellington Ave, Ste C-413, Chicago, II 60657, USA. Safety and efficacy of oral sotalol for sustained ventricular tachyarrhythmias refractory to other antiarrhy- thrnic agents. Amer J CordioZ 1993; 72: (4) AS6

Khanderia U, Jaffe CA, Theisen V. Univ Michigan, Med Ctr, Dept Phann Sew, IS00 E Med Ctr Dr, Ann Arbor, Mi 48109, USA. Amiodarone-induced thyroid dysfunction. Clin Pharmacy 1993;

CURRENT AWARENESS M PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 533

12: (10) 774 Kim SC, Won JH, Ahn SK. Yonsei Univ, Wonju Coll Med, Dept

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534 CURRENT AWARENESS IN PHARh4ACOEPIDEMIOLOGY AND DRUG SAFETY

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5 CNS DEPRESSIVE AGENTS

Ketorolac and renal failure. Med J Aurfraliu 1993; 159: (7) 488 Albanese J, Durbec 0, Viviand X, Potie F, Alliez B, Martin C. Hop

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Brandon G. Paracetamol Informat Ctr, Ste 201A, Butlers Wharf, 45 Curlew St, London SEl 2ND, England. The fatal paracetamol dosage - How low can you go? (Letter). Med Sci Law 1993; 3 3 (3) 274

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Francois M. Hop Robert Debre, Sen, ORL, 48 Blvd Smrier, F-75019 Paris, France. Efficacy and safety of phenazonelidocaine hydrochloride ear drops (Otipaxm) in infants and children with congestive myringitis. Ann Pediaf 1993; 4 0 (7) 48 1

Fuller DK, Kalekas PJ. Univ Nevada, Sch Med, Dept Internal Med,


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Isojarvi JIT, Laatikainen TJ, Parkarinen AJ, Juntunen KTS, Myllyla VV. Univ Oulu, Dept Neurol, SF-90220 Oulu, Finland. Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy. NEngl JMed 1993; 329 (19) 1383

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Kikura M, Ikeda K. Hamamatsu Univ, Sch Med, Dept Anesthesiol &

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Rousseau P, Fuentevilla-Clifton A. 5322 W N Lane, Glendale, Az 85302, USA. Acetazolamide and salicylate interaction in the elderly - A case report. J Amer Geriaf Soc 1993; 41: (8) 868

Scheider DM, Klygis LM, Tsang TK*, Caughron MC. *Northwestem Univ, Evanston Hosp, McGaw Med Ctr, 2650 Ridge Ave, Evan- ston, II 60201, USA. Hepatic dysfunction after repeated isoflurane administration. J Clin Gusfroenterol 1993; 17: (2) 168

Shah P, O’Donnell B, Pochkhanawala F, Tan CY. Birmingham & Midland Eye Hosp, Dept Ophthalmol, Birmingham, England. Se- vere exacerbation of rosacea by oral acetazolamide (Letter). Brit J Dermufol 1993; 129 (5) 647

Sharief MK, Sander JWA, Shorvon SD. lnst Neurol, Epilepsy Res Grp, London WClN 3BG, England. Acute encephalopathy with vigabatrin (Letter. Lancet 1993; 342: (8871) 619

Shriner K, Goetz MB. Sepulveda Vet, Adm Med Ctr, Sepulveda, Ca, USA. Acetaminophen hepatotoxicity augmented by zidovudine (Reply). Amer J Med 1993; 9 5 (3) 342

Smith K, Halliwell RMT*, Lawrence S, Klineberg PL, O’Connell P. *Westmead Hosp, Dept Anaesthesia, Westmead, NSW 2145, Aus- tralia. Acute renal failure associated with intramuscular ketorolac (Case Report) Anuesth Intensive Cure 1993; 21: (5) 700

Speny RJ. Univ Utah, Dept Anesthesiol, 50 Nth Med Dr, Salt Lake City, Ut 84132, USA. Cerebrovascular autoregulation may be the probable mechanism responsible for fentanyl-induced and sufentanil-induced increases in intracranial pressure in patients with head trauma (Reply). Anesthesiology 1993; 7 9 ( I ) 187

Steinberg RB, Gilman DE, Johnson F. Baystate Med Ctr, Dept Anes- thesiol, Springfield, Ma 01199, USA. Acute toxic delirium in a patient using transdermal fentanyl. Anesth Anulg 1992; 75: (6) 1014

Stone PA, Maclntyre PE, Jarvis DA. Westem Infirm & Associated Hosp, Dept Anaesthesia, Glasgow GI I 6NT, Scotland. Norpethid- ine toxicity and patient controlled analgesia (Case Report). Brit J

Anaesth 1993; 71: ( 5 ) 738 Stuppaeck CH, Whitworth AB, Fleischhacker WW. Innsbruck Univ,

Psychiat Klin, Anichstr 35, A-6020 Innsbruck, Austria. Abuse potential of carbamazepine. JNerv Ment Dis 1993; 181: (8) 519

Thisted E, Ebbesen F. Univ Copenhagen, Hvidovre Hosp, Dept Pae- diat, Kettegards Alle 30, DK-2650 Hvidovre, Denmark. Malforma- tions, withdrawal manifestations, and hypoglycaemia a k r exposure to valproate in ufero. Arch Dis Child 1993; 6 9 (3 Spec Issue) 288

Trehan R, Clark CF. Address not available. Valproic acid-induced truncal weakness and respiratory failure. Amer J Psjvhiuf 1993; 150: (8) 1271

Tsuji M, Hori S, Asai N, Hamanaka T, Ishikawa T, Hiyoshi T, Mo- chizuki H. Address not available. Two epileptics showing antiepileptic drug-induced psychoses. Jpn J Psychiuf Neurof 1993; 47: (2) 298

Wang CY. Address not available. Respiratory depression after extradural fentanyl (Reply). BritJAnaesth 1993; 71: (1) 166

Wark H. Childrens Hosp, Sydney, Australia. Hepatotoxicity of vola- tile anaesthetic agents (Letter). Brif JAnuesth 1993; 71: (4) 610

Webster J, Piscitelli G, Polli A, Dalberton A, Falsetti L, Ferrari C, Fioretti P, Giordano G, Lhermite M, Ciccarelli E ef ul. c/o Scanlon MF, Univ Wales Coll Med, Dept Med, Heath Pk, Cardiff CF4 4XN, Wales. The efficacy and tolerability of long-term cabergoline therapy in hyperprolactinaemic disorders - An open, uncontrolled, multicentre study. Clin Endocrinol 1993; 3 9 (3) 323

Weig SG, Pollack P. Univ Massachusetts, Med Ctr, Sch Med, Dept Pediat, Div Neurol, Worcester, Ma 01655, USA. Carbamazepine- induced heart block in a child with tuberous sclerosis and cardiac rhabdomyoma: Implications for evaluation and follow-up. A n n Neurol 1993; 34: (4) 617

Wildsmith JAW. Royal Edinburgh & Associated Hosp, Dept Anaes- thet, Edinburgh EH3 9YW, Scotland. Anaphylactoid reaction following local anaesthesia for epidural block (Letter). Anaesthesia 1993; 48: (10) 916

Woo M, Sugimoto T, Nishida N, Sasaki T, Murakami K, Yasuhara A, Amki A, Kobayashi Y. Kansai Med Univ, Otokoyama Hosp, Dept Pediat, Yawata, Japan Valproate retard granule - Efficacy and side effects. Jpn JPsychiut Neurol 1993; 47: (2) 288

6 NON-STEROIDAL ANTI-INFLAMMATORY AGENTS

Abraham J. Univ Reading, Dept Sociol, POB 218, Reading RG6 2AA, England. Scientific standards and institutional interests: Car- cinogenic risk assessment of benoxaprofen in the UK and United States. Soc StudSci 1993; 23: (3) 387

Alioth C, Blum RA, Dandrea DT, Kochak GM, Teng LC, Ziehmer BA, Schentag JJ, Chan KKH*. *Ciba Geigy Corp, Div Phar- maceuf 444 Saw Mill River Rd, Ardsley, NY 10502, USA. Appli- cation of dual radiotelemetric technique in studying drug-drug interaction between diclofenac sodium and ranitidine HCI in volunteers. Phurmuceut Res 1993; 10: (1 1 ) 1688

Al-Quorain AA, Satti MB, Manvah S, Al-Nahdi M, Al-Habdan I. Univ Al-Khobar, King Fahd Hosp, Dept Internal Med, POB 40001, Al-Khobar 3 1952, Saudi Arabia. Non-steroidal anti-inflammatory drug-induced gastropathy: A comparative endoscopic and histopathological evaluation of the effects of tenoxicam and diclofenac. J Int Med Res 1993; 21: (2) 89

Appadurai IR, Power I. Univ Wales Coll Med, Dept Anaesthet, Car- diff CF4 4XN, Wales. NSAIDs in the postoperative period - Use with caution in elderly people (Letter). Erif Med J 1993; 307: (6898) 257

Begaud B, Chaslerie A, Came X, Bannwarth B, Laporte JR, Sorbette F, Montastruc P. Hop Pellegrin, Dept Clin Pharmacol, F-33076 Bordeaux, France. Upper gastrointestinal bleeding associated with


analgesics and NSAID use - A case-control study (Letter). J Rheu- m a i d 1993; 2 0 (8) 1443

Benz J, Wiedbrauck F, Hob: J*. *Allegemeines Krankenhaus Celle, Gastroenterol Klin, Siemensplak 4, D29223 Celle, FRG. On the epidemiology of NSAIDassociated ulcers of the gastrointestinal tract in comparison with peptic ulcers in the stomach and duode- num - A 5 year analysis of a hospital patient population (German, English Abstnrct). Med Klin 1993; 88: (8) 463

Bjamason I. Kings Coll Med, Dept Clin Biochem, Bessemer Rd, Lon- don SE5 9PJ, England. Pathophysiology of nonsteroidal anti-inflammatory drug-induced intestinal strictures (Reply). Gasfroen- rerology 1993; 105: (5) 1590

Brandt KD. Indiana Univ, Sch Med, Div Rheumatol, Indianapolis, In 46202, USA. NSAIDs in the treatment of osteoarthritis: Friends or foes? Bull Rheumar Dis 1993; 42: (6) 1

Cutler C, Rex DK, Cummings OW. Indiana Univ, Sch Med, Indian- apolis, In 46202, USA. Per anus enteroscopic demonstration of a non-steroidal anti-inflammatory drug induced ileal stricture (Let- ter). Gacrroinresr Endoscop 1993; 3 9 (4) 601

Davis AE, Patterson F. Price of Wales Hosp, Gastrointestinal Unit, Randwick, NSW 2031, Australia. Co-carcinogenic effect of sulphasalazine (Reply). Brir J Cancer 1993; 68: (5 ) 1044

Defranchis R, Vecchi M, Carpinelli L, Meucci G, Torgano G. Univ Milan, 1st Med Intema, Gastroenterol & Gastrointestinal Endo- scopy Sew, via Pace 9, 1-20122 Milan, Italy. Comparison of the efficacy and safety of sulphasalazine and mesalazines in the main- tenance treatment of ulcerative colitis - A meta-analysis. Eur J Gasfroenterol Hepator 1993; 5 (7) 505

Dekonvin JD, Lapicque F, Trechot P, Netter P. Hop Cent, Sew Med Interne H, F-54000 Nancy, France. Unknown intake of nonsteroidal anti-inflammatory drugs and digestive bleeding - Clinical and drug assay assessment. Amer J Gasfroenterol 1993; 88: (8) 1298

Demoor A, Van Hecke E, Kestelyn P. State Univ Ghent Hosp, Dept Dermatol, 9-9000 Ghent, Belgium. Contact allergy to penicil- lamine in eyedrops. Contact Dermatitis 1993; 2 9 (3) 155

Drosos AA, Christou L, Galanopoulou V, Tzioufas AG, Tsiakou EK. Univ Ioannina, Sch Med, Dept Internal Med, Div Rheumatol, GR- 451 10 Ioannina, Greece. DPenicillamine induced myasthenia gravis - Clinical, serological and genetic findings. Clin Exp Rhewnatol 1993; 11: (4) 387

Fennerty MB. Arizona Hlth Sci Ctr, Dept Med, Gastroenterol Sect, 1501 Nth Campbell Ave, Tucson, Az 85724, USA. Nonsteroidal anti-inflammatory drugs, ulcers, and histamine(2) blockers: The os- trich phenomenon (Editorial). Arch Intern Med 1993; 153: (21) 241 1

Fenn GC. GD S a l e & Co Ltd, POB 53, High Wycombe HPl2 4HL, England. NSAIDs in the postoperative period - Don’t dismiss gastric erosion (Letter). Brit Med J 1993; 307: (6898) 258

Fujita H, Matsuo 1. Tokai Univ, Sch Med, Dept Molec Life Sci, I se hara, Kanagawa 2591 1, Japan. Type I lipid photo-oxidation by the nonsteroidal anti-inflammatory drug suprofen: A possible key to its photosensitivity. Phorodermatol Photoimmwrol Photomed 1993; 9 (5) 203

Gabay C, De Bandt M, Pa lam E. Hop Cantonal Univ, Div Rheuma- tol, CH-1211 Geneva 14, Switzerland. Sulphasalazine-related life threatening side effects - Is N-acetylcysteine of therapeutic value? (Case Report). Clin Exp Rhewnaroll993; 11: (4) 417

Gargot D, Chaussade S. Hop La Source, Serv Hepatogastroenterol, BP 6709, F-45067 Orleans, France. Nonsteroidal anti-inflammatory drug-induced consequences and disease in the small and large bowel. 2. Effects of NSAIDs on bowel. Gattroen Clin Biol 1993;

Gibson P, Eadington DW, Winney RJ. Royal Edinburgh & Associ- ated Hosp, Med Renal Unit, Edinburgh EH3 9YW, Scotland. NSAlDs in the postoperative period - Clinical experience confirms risk (Letter). Brir Med J 1993; 307: (6898) 257

Goldmann R, Schuppe HC, Gleichmann E, Kind P, Merk H, Rau R, Goen G. Heinrich Heine Univ, Dept Dermatol, Moorenstr 5, W-

17: (8-9) 553

4000 Dusseldorf, FRG. Adverse immune reactions to gold in rheumatoid arthritis - Lack of skin reactivity. Acra Dermaro-Venereol 1993; 73: (3) 220

Habal FM, Hui G, Greenberg GR. Toronto Hosp, Gen Div, Div Gas- troenterol, EN 9-229,200 Elizabeth St, Toronto, Ontario, Canada MSG 2C4. Oral 5-aminosalicylic acid for inflammatorv bowel disease in pregnancy - Safety and clinical course. Gas&oenterologV 1993; 105: (4) 1057

Hard0 PG, Chalmers DM, Jakeways M, Wright V, Axon ATR. Rheu- matol & Rehabil Res Unit, Registrar Rehabil Gen Med, 36 Claren- don Rd, Leeds LS2 9NZ, England. Management of NSAIDs-related dyspepsia in the community. Brit J Clin Pracr 1993; 47: (5) 24 1

Henry D, Dobson A, Tumer C. Mater Misericordiae Hosp, Discipline Clin Pharmacol, Clin Sci Bldg, Waratah, NSW 2298, Australia. Variability in the risk of maior gastrointestinal com~lications for nonaspirin nonsteroidal anti-inflammatory drugs. Ga&oenterology 1993; 105: (4) 1078

Holt S, Rigoglioso V, Sidhu M, Irshad M, Howden CW, Mainer0 M. Seton Hall Univ, 268 ML King Jr Blvd, Newark, NJ 07102, USA. Nonsteroidal antiinflammatory drugs and lower gastrointestinal bleeding. DigestDisSci 1993; 3 8 (9) 1619

Irving GA. Univ Cape Town, Dept Anaesthet, Cape Town, Rep Sth Africa. Safety of non-steroidal anti-inflammatories before adeno- tonsillectomy (Letter). Srh Afr Med J 1993; 83: (8) 614

Jobard JM, Ory JP, Cleau D, Debieuvre D. Ctr Hosp Gen Paul Morel, Serv Med Hepatogastroenterol 9, F-70014 Vesoul, France. Symg tomatic hepatitis after tenoxicam administration (Letter) (French, English Abstract). Gasfroen CIin Biol 1993; 17: (8-9) 614

Katz Y, Goldberg N, Kivity S. Tel Aviv Univ, Sackler Fac Med, Assaf Harofeh Med Ctr, Alergy & Immunol Unit, IL-70300 Zeri- fin, Israel. Localized periorbital edema induced by aspirin. AIlergV 1993; 48: (5) 366

Keating JP, McIlwaine I. Wellington Hosp, Dept Surg, Wellington, New Zealand. Simultaneous small and large bowel ulceration associated with short term NSAID use (Letter). N 2 Med J 1993; 106: (965) 438

Konturek JW, Dembinski A, Stoll R, Konturek M, Domschke W*. Wniv Munster, Dept Med B, Albert Schweitzer Str 33, W-4400 Munster, FRG. Gastric mucosal blood flow and neutrophil activation in aspirin-induced gastric mucosal damage in man. Scand J Gasfroenrerol 1993; 28: (9) 761

Magnus JH, Elverland HH, Olsen EG, Husby G. Univ Tromso, Inst Clin Med, Dept Rheumatol, PO9 12, N-9038 Tromso, Norway. Facial palsy and partial accommodative insufficiency associated with sulphasalazine treatment in a patient with ankylosing spon- dylitis. ScandJRheumatol 1993; 22: (4) 199

Masud T, Winocour P, Clarke F. Freeman Rd Hosp, High Heaton, Newcastle upon Tyne NE7 7DN, England. Reversible hyporeni- naemic hypoaldosteronism and life-threatening cardiac dysrhyth- mias - The interaction of non-steroidal anti-inflammatory drugs and autonomic dysfunction (Letter). Posrgrad Med J 1993, 6 9 (813) 593

McIntire SC, Rubenstein RC, Gartner JC, Gilboa N, Ellis D. Univ Pittsburgh, Childrens Hosp Pittsburgh, Sch Med, Dept Pediat, Pittsburgh, Pa 15213, USA. Acute flank pain and reversible renal dysfunction associated with nonsteroidal anti-inflammatory drug use. Pediafrics 1993; 92: (3) 459

Meenan J. Univ Amsterdam, Acad Med Ctr, Dept Gastroenterol, Biomed 1 Programme, Meibergdreef, 1105 AZ Amsterdam, The Netherlands. Co-carcinogenic effect of sulphasalazine (Letter). Brit JCancer 1993; 68: (5) 1043

Melillo G, Padovano A, Cocco G, Masi C. Fdn Clin Lavoro, Div Pneumol, via Nino Bixio 10, Campoli, Italy. Dosimeter inhalation test with lysine acetylsialicylate for the detection of aspirin-induced asthma. Ann Allergy 1993; 71: ( I ) 61

Morales WJ, Madhav H. 94 W Underwood St, Orlando, FI 32806, USA. Efficacy and safety of indomethacin compared with magne-


sium sulfate in the management of preterm labor - A randomized study. Amer J Obsfet & Gynecol 1993; 169 ( I ) 97

Murray HG. Address not available. Fetal pleural effusion following maternal indomethacin therapy (Brir J Obsrer Gynaecol 1993, 100 277) (Correction). Erir J Obsfet Gynuecol 1993; 100: (8) 785

O'Callaghan CA, Andrews PA, Ogg CS. Guys Hosp, Renal Unit, London SEI 9RT, England. NSAIDs in the postoperative period - Many factors threaten renal function (Letter). Brit Med J 1993; 307: (6898) 257

Oren R, Ligumsky M, Lysy J, Gonzales J, Zimmennan J. Hadassah Univ Hosp, Dept Med, Mt Scopus, POB 24035, IL-91120 Jerusa- lem, Israel. Gastro-duodenal injury associated with intake of 100- 325 mg aspirin daily. Posfgrud Med J 1993; 6 9 (815) 712

Pastuszak A, Pinelli M, Koren G*. *Hosp Sick Children, Div Clin Pharmacol, Motherisk Program, 555 Univ Ave, Toronto, Ontario, Canada M5G 1x8. Pregnancy outcome following fetal exposure to tiaprofenic acid in the first trimester. Amer J Perinafol 1993; 1 0 (5) 354

Pigatto PD, Mozzanica N, Bigardi AS, Legori A, Valsecchi R, Cusano F, Tosti A, Guarrera M, Balato N, Sertoli A. Univ Milan, Dept Dematol 2, via Pace 9, 1-20122 Milan, Italy. Topical NSAID allergic contact dermatitis Italian experience. Contact Dermafifis 1993; 2 9 ( I ) 39

Pond SM, Armstrong JG, Henderson A. Univ Queensland, Princess Alexandra Hosp, Div Med, Brisbane, Qld 4102, Australia. Late diagnosis of chronic salicylate intoxication (Letter). Lancet 1993; 342: (8872) 687

Power I. Univ Wales Coll Med, Cardiff CF4 4XN, Wales. Aspirin-induced asthma (Editorial). Brit JAnaesrh 1993; 71: (5) 619

Quinn CM, Bjamason I, Price AB. Univ Leeds, Acad Unit Pathol, Leeds LS2 9JT, England. Gastritis in patients on non-steroidal anti- inflammatory drugs. Hisroprhologv 1993; 23: (4) 341

Rainsford KD, James C, Johnson DM, Stetski PI, Hill RE, Salena BJ, Hunt RH. Address not available. Effects of chronic NSAIDs on gastric mucosal injury related to mucosal prostanoids, and plasma drug concentrations in human volunteers. Agent Acfion 1993; 39: (Sp issue CI) C21

Rainsford KD. Address not available. Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage. Agenr Acfion 1993; 39: (Sp Issue CI) C24

Rooney Tw, Furst DE*, Koehnke R, Burmeister L. *Virginia Mason Med Ctr, Clin Res Programs, 1100 9th Ave, POB 900, Seattle, Wa 98111, USA. Aspirin is not associated with more toxicity than other nonsteroidal antiinflammatory drugs in patients with rheumatoid arthritis with methotrexate. JRheumufol 1993; 2 0 (8) 1297

Schlondorff D. Yeshiva Univ Albert Einstein Coll Med, Div Nephrol, 1300 Morris Pk Ave, Bronx, NY 10461, USA. Renal complications of nonsteroidal anti-inflammatory drugs (Nephrology Forum). Kidney In? 1993; 44: (3) 643

Schmassmann A, Fehr HF, Locher J, Klotz U. Univ Bern, Inselspital, Gastrointestinal Unit, CH-3010 Bern, Switzerland. Pharmacokinet- ics and toxicity of high-dose topical colonic 5-aminosalicyclic acid therapy in patients with severely active total ulcerative colitis. Eur J Gusrroenterol Heprol 1993; 5: (1 1) 927

Schoonjans R, Mast A*, Van den Beele G, Dewilde D, Achten E, Van Maele V, Pauwels W. *Algemene Klin H Familie, Dept Gas- troenterol, Groenebriel I , B-9000 Ghent, Belgium. Sulfasalazine- associated encephalopathy in a patient with Crohn's disease. Amer JGasrroenterol 1993; 88: (9) 1416

Schoonjans R, Mast A*, Van den Abeele G, Dewilde D, Achten E, Van Maele V, Pauwels W. *Algemene Klin Heilige Famille, Dept Gastroenterol, Groenebriel 1, B-9000 Ghent, Belgium. Sulfa- salazine-associated encephalopathy in a patient with Crohn's disease. Amer J Gusrroenreroll993; 88: (1 0) 1759

Shorr RI, Ray WA, Daugherty JR, Griffin MR. Vanderbilt Univ, Med Ctr, Sch Med, Dept Prevent Med, Div Pharmacoepidemiol, Nash- ville, Tn 37232, USA. Concurrent use of nonsteroidal anti-inflammatory drugs and oral anticoagulants places elderly persons at high

risk for hemorrhagic peptic ulcer disease. Arch Inrern Med 1993; 153: (14) 1665

Silagy CA, McNeil JJ, Donnan GA, Tonkin AM, Worsam B, Cam- pion K. Monash Univ, Alfred Hosp, Dept Social & Prevent Med, Commercial Rd, Prahran, Vic 3181, Australia. Adverse effects of low-dose aspirin in a healthy elderly population. Clin Phonnacol Ther 1993; 54: ( I ) 84

Taha AS, Dahill S, Nakshabendi I, Lee FD, Sturrock RD, Russell RI. Sthn Gen Hosp, Ctr Gastroenterol, Glasgow G51 4TF, Scotland. Duodenal histology, ulceration, and Helicobacter wlori in the presence or absence of non-steroidal anti-inflammatory drugs. Gut 1993; 34 (9) 1162

Valcamonico A, Foschini M, Soregaroh M, Tarantini M, Frusca T. Univ Brescia, Obstet & Ginecol Clin, Spedali Civili Brescia, I- 25100 Brescia, Italy. Low dose aspirin in pregnancy - A clinical and biochemical study of effects on the newborn. J Perinat01 Med 1993; 21: (3) 235

Valsecchi R, Pansera B, Di Landro A, Cainelli T. Osped Riuniti Ber- gamo, Dept Dermatol, 1-24100 Bergamo, Italy. Contact sensitivity to piroxicam. Contact Dermuritis 1993; 2 9 (3) 167

Vogelgesang SA, Dennis GJ, Bauer FA. Walter Reed Army Res Ctr, Washington, DC 20307, USA. Proteinuria associated with tolmetin treatment in a patient with systemic lupus erythematosus. Arthritis Rheum 1993; 36: (8) 1181

Whitcomb DC. Div Gastroenterol & Hepatol, Rm 571 Scaife Hall, 3550 T m c e St, Pittsburgh, Pa 15261, USA. Pathophysiology of nonsteroidal anti-inflammatory drug-induced intestinal strictures (Letter). Gasrroenterologv 1993; 105: (5) 1590

Wilkieson CA, Madhok R*, Hunter JA, Capell HA. *Gartnavel Royal Hosp, Dept Rheumatol, 1053 Great West Rd, Glasgow GI2 O W , Scotland. Toleration, side effects and efficacy of sulphasalazine in rheumatoid arthritis patients of different ages. Quart J Med 1993; 86: (8) 501

Worsley MH. Stirling Royal Infirm, Dept Anaesthet, Stirling FK8 2AU, Scotland. NSAIDs in the postoperative period... and after major surgery (Letter). Erir Med J 1993; 307: (6898) 257

Yamanaka H, Hakoda M, Kamatani N, Kashiwazaki S, Carson DA. Tokyo Womens Med Coll, Inst Rheumatol, KS Bldg, 2-19 Waka- matsu cho, Shinkuku ku, Tokyo 162, Japan. Formation of DNA strand breaks by Dpenicillamine and bucillamine in human lymphocytes. Immunopharmacologv 1993; 2 6 (2) 113

7 CNS AGENTS

Adam K, Oswald I. Address not available. Triazolam - Small studies miss the difference (Letter). Erif Med J 1993; 307: (6904) 626

Adam CE, Barnes TRE, Essali MA, Hirsch SR, MacKay AVP, Cor- rigan FM, Cutting JC, Ekdawi MY, McKenna PI, Milln PTS er al. Charing Cross & Westminster Med Sch, London, England. The safely and efficacy of clozapine in severe treatment-resistant schizophrenic patients in the UK. Brit J Pgchiar 1993; 163: (AUG) 150

Amitai Y, Erickson T, Kennedy El, Leikin JB, Hryhorczuk DO, No- ble J, Hanashiro PK, Frischer H*. *Rush Univ, Rush Presbyterian St Lukes Med Ctr, Dept Phannacol, Chicago, I1 60612, USA. Tri- cyclic antidepressants in red cells and plasma - Correlation with impaired intraventricular conduction in acute overdose. Clin Phar- macol Ther 1993; 54: (2) 219

Baele P, Kestens-Servaye Y, Goenen M. UCL, Dept Intens Care, Dept Anesthesiol, B-1200 Brussels, Belgium. MA01 and cardiac surgery (Letter). Can JAnaesfh 1593; 40: (6) 579

Balon R, Yeragani VK, Pohl R, Ramesh C. Univ Detroit, Ctr Psy- chiat, 271 E Jefferson St, 2nd Floor, Detroit, Mi 48207, USA. Sex- ual dysfunction during antidepressant treatment. J C h Psychiar 1993; 54: (6) 209

Bergman U, Myrhed M. Karolinska Inst, Huddinge Univ Hosp, Dept Clin Pharmacol, S-14186 Huddinge, Sweden. Benzodiazepine use


in Sweden (Letter). Lancer 1993; 342: (8867) 373 Biban P, Baraldi F, Pettenazzo A, Filippone M, Zacchello F. Univ

Padua, Dept Pediat, via Giustiniani 3, 1-35128 Padua, Italy. Ad- verse effect of chloral hydrate in two young children with obstructive sleep apnea. Pediatrics 1993; 92: (3) 461

Bredbacka PE, Paukkala E, Kinnunen E, Koponen H. Moisio Hosp, SF-50520 St Michel, Finland. Can severe cardiorespiratory dys- regulation induced by clozapine monotherapy by predicted? Inr CIin Psychopharmacol 1993; 8: (3) 205

Buist A, Norman TR, Dennerstein L. Univ Melbourne, Key Ctr Womens Hlth SOC, Grattan St, Parkville, Vic 3052, Australia. Plasma and breast milk concentrations of dothiepin and northiaden in lactating women. Hum Psychopharmacol Clin Exp 1993; 8: ( I ) 29

Cabaniss DL, Roose SP. New York State Psychiat Inst & Hosp, 722 West 168th St, PI Box 90, New York, NY 10032, USA. Late onset tricyclic-induced agranulocytosis with an atypical course. fharma- copsychiafiy 1993; 2 6 (4) 130

Caccia S, Confalonieri S, Guiso G, Lucca U, Parma E, Guido M, Tettamanti M, Tiraboschi P, Spagnoli A. Mario Negri Inst Pharma- col Res, Drug Metab Lab, via Eritrea 62, 1-20157 Milan, Italy. Single dose safety and phannacokinetics of a potential cognition- enhancing compound, (31-275,838, in healthy volunteers. J CIin Pharmacol1993; 33: (9) 845

Cade L, King M, Ashley J. Royal Womens Hosp, Carlton, Vic 3053, Australia. Lack of extrapyramidal side effects from droperidol in low dose (Letter). Anesrh Intensive Care 1993; 21: (4) 479

Callahan AM, Fava M, Rosenbaum JF*. *Massachusetts Gen Hosp, Coordinated Sci Unit, WACC 815, 15 Parkman St, Boston, Ma 021 14, USA. Drug interactions in psychopharmacology. Psychiar Clin Nrh Amer 1993; 1 6 (3) 647

Caracci G, Reggev A. Cabrini Med Ctr, Dept Psychiat, 227 East 19th St, New York, NY 10003, USA. Atrial fibrillation and nortriptyline in the elderly. Inr J Geriar Psychiar 1993; 8: (7) 577

Cavallaro R, Regazzetti MG, Covelli G, Smeraldi E. Univ Milan, San Raffaele Hosp, Sch Med, Dept Neuropsychiat Sci, 1-20127 Milan, Italy. Tolerance and withdrawal with mlpidem (Letter). Lancet 1993; 342: (8867) 374

Chaves MLF, Bianchin M, Peccin S, Rotta F, Jardim C, Gianlupi A, Eidt L. Hosp CIin Porto Alegre, Serv Neurol, Ramiro Barcelos 2350 Sala 2040, BR-90210 Porto Alegre, Brazil. Chronic use of benmdiazepines and cognitive deficit complaints: A risk factor study. Ital J Neurol Sci 1993; 14: (6) 429

Cohn MA. Sleep Disorders Ctr SW Florida, 848 1st Ave Nth, Naples, FI 33940, USA. Effects of zolpidem, codeine phosphate and placebo on respiration: A double-blind, crossover study in volunteers. DrugSafeety 1993; 9 (4) 312

Cookson J. Royal London Hosp, London, England. Side-effects of antidepressants. Brit J Psychiat 1993; 163: (Suppl20) 20

Cormble E, Puech AJ*. *Grp Hosp Pitie, Salpetriere, Serv Pharmacol, F-75651 Paris 13, France. How to improve the risk benefit ratio of antidepressants. Inr CIin Psychopharmacol 1993; 8: (4) 237

Cutler NR, Sramek JJ, Wardle TS, Hesselink JMK, Roeschen JK. Calif Clin Trials, 8500 Wilshire Blvd, 7th Floor, Beverly Hills, Ca 9021 1, USA. The safety and efficacy of ipsapirone vs lorazepam in outpatients with generalized anxiety disorder (GAD): Single site findings from a multicenter trial. Psychopharmacol Bull 1993; 29: (2) 303

Derby LE, Gutthann SP, Jick H*, Dean AD. *Boston Univ, Med Ctr, Boston Collaborat Drug Surveillance Program, 1 1 Muzzey St, Lex- ington, Ma 02173, USA. Liver disorders in patients receiving chlorpromazine or isoniazid. Phrmacorherapy 1993; 13: (4) 353

Dietrich A, Mortensen ME*, Whelk J. *Ohio State Univ, Dept Pediat, Div Clin Pharmacol Toxicol, 700 Childrens Dr, Columbus, Oh 43205, USA. Cardiac toxicity in an adolescent following chronic lithium and irnipramine therapy. J Adolescent Healrh 1993; 14: (5) 394

Diez-Martin JM, Herrero-Sanchez A, Franch-Valverde JI. Univ Hosp Valladolid, Dept Psychiat, Ramon y Cajal SN, E-47005 Valladolid, Spain. Case report. 3. Neuroleptics withdrawal syndrome in a manic depressive patient. J Drug Dev 1993; 6 (2) 73

Dixon L, Thaker G, Conley R, Ross D, Cascella N, Tamminga C*. *Maryland Psychiat Res Ctr, POB 21247, Baltimore, Md 21228, USA. Changes in psychopathology and dyskinesia after neuroleptic withdrawal in a double-blind design. Schizophr Res 1993; 1 0 (3) 267

Donnan GA, Darby D, Cunningham MA. Address not available. Amantadine withdrawal and neuroleptic malignant syndrome (Re- ply). Neurologv 1993; 43: (10) 2155

~rummer OH, Syjanen ML, Cordner SM. Monash Univ, Dept Forens Med, 57-83 Kavanagh St, Sth Melbourne, Vic 3205, Aus- tralia. Deaths involving the benzodiazepine flunitrazepam. Amer J Foren Medfarh 1993; 14: (3) 238

Durst R, Dorevitch A, Fraenkel Y. Hebrew Univ Jerusalem, Hadassah Med Sch Hosp, Talbieh Mental Hlth Ctr, POB 39, IL-91OOO Jeru- salem, Israel. Platelet dysfunction associated with clozapine therapy (Letter). Southern Med J 1993; 86: ( 10) 1 170

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Frank H, Gurtner HP, Kneussl M, Lang.1, Mlczoch J. Univ Vienna, Inneren Med Klin 2, Kardiol Abt, Wahringer Gurtel 18-20, A-1090 Vienna, Austria. Aminorex-induced plexogenic pulmonary arte- riopathy - 25 years after the epidemic event. 2 Kardiol 1993; 8 2 (9) 568

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Iruela LM, Ibanez-Rojo V, Baca E. Univ Autonoma Madrid, Clin Puerta Hierro, Dept Psychiat, E-28035 Madrid, Spain. Zolpidem induced macropsia in anorexic woman (Letter). Lancer 1993; 3 4 2 (8868) 443

Jacquy J, Mettens P, BIum S, Jacqmotte N, Van der Heyden JE. Hop Civil Charleroi, Serv Neurol, Blvd Joseph 2, B-6OOO Charleroi, Belgium. Long-latency auditory evoked potentials in Parkinson's disease and neuroleptic-induced Parkinsonism (French). Acfa Neurol Berg 1993; 93: (3) 119

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Linden M. Free Univ Berlin, Dept Psychiat, Outpatients Res Grp,

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Linden M, Gothe. Freien Univ Berlin, Dept Psychiat, Psychiat Klin, Forschingsgrp Ambulante Therapie, Eschenallee 3, D- 14050 Ber- lin, FRG. Bediazepine substitution in medical practice - Analy- sis of pharmacoepidemiologic data based on expert interviews. Pharmacopg,vhiuby 1993; 2 6 (4) 107

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Monteiro MLR, Sampaio CM. Rua Mato Grosso 128 Conj 51, BR- 01239 Sao Paulo, Brazil. Lithium-induced downbeat nystagmus in a patient with Arnold-Chiari malformation (Letter). Amer J Ophfhalmol 1993; 116: (5) 648

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Philpott NJ, Marsh JCW, Gordon-Smith EC, Bolton JS. St George Hosp, Dept Haematol, London SW17 ORE, England. Aplastic anaemia and remoxipride (Letter). Lancet 1993; 342 (8881) 1244

Rascati KL, Rascati El. Univ Texas, Coll Pharm, Austin, Tx 78712, USA. Use of clozapine in Texas State Mental Health facilities. Amer JHosp Phurm 1993; 50: (8) 1663

Ratan DA, Smith AHW. Royal Dundee Life Hosp, Dundee Psychiat Serv, Dundee DD2 5NF, Scotland. Neuroleptic malignant syndrome secondary to droperidol (Letter). Biol Psychiut 1993; 34: (6) 42 1

Reid WH, Pham VA, Rag0 W. Natl Assoc State Mental Hlth Program Directors, Washington, DC, USA. Clozapine use by state programs - Public mental health systems respond to a new medication. Hosp Communi@ Psychiui 1993; 44: (8) 739

Rosen J, Sweet R, Pollock BG, Mulsant BH. Univ Pittsburgh, West- em Psychiat Inst & Clin, Sch Med, Dept Psychiat, Pittsburgh, Pa 15213, USA. Nortriptyline in the hospitaliizd elderly: Tolerance and side effect reduction. Psychophurmucol Bull 1993; 2 9 (2) 327

Rosenqvist M, Bergfeldt L, Aili H, Mathe AA. Karolinska Hosp, Karolinska lnst, Thorac Clin, Dept Cardiol, S-10401 Stockholm 60, Sweden. Sinus node dysfunction during long-term lithium treatment. Brit Heart J 1993; 7 0 (4) 371

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Saletu B, Barbanoj MJ, Anderer P, Sieghart W, Gtunberger J. Univ Vienna, Dept Psychiat, Psychiat Klin, Pharmacopsychiat Sect, Wa- hringer Gurtel 18-20, A-1090 Vienna, Austria. Clinical-pharmacol- ogical study with the 2 isomers (D, L) of fenfluramine and its comparison with chlorpromazine and Damphetamine - Blood levels, EEG mapping and safety evaluation. Meth Find Exp Clin Phurmucol 1993; 15: ( 5 ) 291

Schindler BA, Ramchandani D. Med Coll Penn, Dept Psychiat, 3300 Henry Ave, Philadelphia, Pa 19129, USA. Partial complex status epilepticus in a lithium-toxic patient. Psychosomutics 1993; 3 4 (6) 521

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Silva RR, Friedhoff AJ, Alpert M. N W Med Ctr, Lkpt Psychiat, 550 1st Ave, New York, NY 10016, USA. Neuroleptic withdrawal psy-

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Tanquy J. SUNY, Coll Med, Dept Psychiat, 750 E Adam St, Syracuse, NY 13210, USA. Lithium neurotoxicity at therapeutic levels in an AIDS patient. JNerv Ment Dis 1993; 181: (8) 51 8

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Tueth MJ. Univ Florida, Gainesville, FI 32611, USA. Psychotropic medications during pregnancy: Risk to the fetus (Letter). J Am Med Assn 1993; 270 (1 8) 2 177

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Van der Waals FW, Mohrs J, Foets M. Univ Amsterdam, Fac Med, 1105 AZ Amsterdam, The Netherlands. Sex differences among recipients of benzodiazepines in Dutch general practice. Brit Med J 1993; 307: (6900) 363

Velabueno A. Autonomous Univ Madrid, Sch Med, Dept Psychiat, E-28008 Madrid, Spain. Triazolam - Narrow safety margin is unac- ceptable (Letter). Brit MedJ 1993; 3W: (6904) 626

Weintraub M, Handy BM. Univ Rochester, Sch Med & Dent, Dept Community & Prevent Med, Box 644, Rochester, NY 14642, USA. Benzodiazepines and hip fracture: The New York State experience. CIin Phurmucol Ther 1993; 54: (3) 252

Weller M, Kornhuber J. Address not available. Amantadine withdrawal and neuroleptic malignant syndrome (Letter). Neurology 1993; 43: (10) 2155

Wilcock GK, Surmon DJ, Scott M, Boyle M, Mulligan K, Neubauer KA, O”eil1 D, Royston VH. Frenchay Hosp, Dept Care Elderly, Bristol BS16 ILE, England. An evaluation of the effcacy and safety of tetrahydroaminoacridine (THA) without lecithin in the treatment of Alzheimer’s disease. Age Ageing 1993; 22: (5) 316

Wilt JL, Minnema AM, Johnson RF, Rosenblum AM. West Virginia Univ, Pulm & Crit Care Med Sect, POB 9166, Morgantown, WV 26506, USA. Torsade de pointes associated with the use of intravenous haloperidol. Ann Intern Med 1993; 119 (5) 391

Zit0 JM, Volavka J, Craig TJ, Czobor P, Banks S, Vitrai J. Nathan S Kline Inst, Psychiat Res, Bldg 37, Orangeburg, NY 10962, USA. Pharmawepidemiology of clozapine in 202 inpatients with schizophrenia. Ann Phurmucother 1993; 27: (10) 1262

Zomberg GL, Hegarty JD. Address not available. Adverse interaction between propoxyphene and phenelzine (Letter). Amer J Pychiur 1993; 150: (8) 1270

‘39 8 ANTI-NEOPLASTIC AGENTS

Akhtar SS, Salim KP, Ban0 ZA. King Fahd Specialist Hosp, POB 2290, A1 Qassim, Saudi Arabia. Symptomatic cardiotoxicity with high dose 5-fluorouracil infusion: A prospective study. Oncofogy 1993; 50: (6) 441

Aladren MJ. Hosp Miguel Servet, Serv Nefrol, P Isabel Catolica 3, Zaragoza, Spain. Cisplatin - Mechanisms of renal toxicity (Edito- rial) (Spanish, English Abstract). Nefiologiu 1993; 1 3 (3) 183


Aladren MJ, Colon JAG, Sanchez AT. Hosp Miguel Servet, Serv Ne- frol, P Isabel Catolica 3, Zaragoza, Spain. Cisplatin nephrotoxicity

Early functional glomerular and tubular changes (Spanish, Eng- lish Abstract). Nefiologia 1993; 13: (3) 217

Alagaratnam TT. Queen Mary Hosp, Dept Surg, Hong Kong, Hong Kong. Sudden death seven days after paclitaxel infusion for breast cancer (Letter). Lancer 1993; 342: (8881) 1232

Anderson NR, Lokich JJ, Moore C. Canc Ctr Boston, Boston, Ma, USA. The syndrome of 5-fluorouracil cardiotoxicity - An elusive cardiopathy (Letter). Cancer 1993; 72: (7) 2287

Bakke SJ, Fossen A, Storm-Mathiesen I, Lie SO. Natl Hosp Norway, Natl Hosp, Dept Neuroradiol, N-0027 Oslo 1, Norway. Long term cerebral effects of CNS chemotherapy in children with acute lymphoblastic leukemia. Pediur Hemutol Oncol 1993; 10: (3) 267

Barbe L, Lesur G, Turner L, Dupont C, Coggia M, Dupuy P, Dona M. Hop Ambroise Pare, Serv Med Interne, F-92104 Boulogne, France. Cardiac toxicity of 5 fluorouracil: Auriculo-ventricular conduction disease (Letter) (French, English Abstract). Gasrroen Clin Biol 1993; 17: (8-9) 603

Bargman H. Address not available. Podophyllin and pregnancy (Let- ter). Inr J Dermatol 1993; 3 2 (9) 691

Barrioz T, Roblot P, Silvain C, Touchard G, Becq-Giraudon B. CHU La Miletrie, Sew Hepatogastroenterol & Assistance Nutr, F-86021 Poitiers, France. Acute cholestasis mimicking cholangitis during melphalan treatment (Letter) (French, English Abstract). Gartroen Clin Eiol 1993; 17: (6-7) 518

Bauduer F, Delmer A, Ibiassi JPN, Hardy AC, Ryckman N, Zittoun R. Hop Hotel Dieu, Serv Hematol, 1 PI Parvis Notre Dame, F- 75181 Paris 04, France. Anaphylactoid reaction to teniposide - Caution is warranted in atopic patients (French, English Abstract). Sem Hop Paris 1993; 6 9 (29) 879

Beard JS, Smith KJ, Skelton HG. Walter Reed Army Med Ctr, Dept Dermatol, Washington, DC 20307, USA. Combination chemotherapy with 5-fluorouracil, folinic acid, and a-interferon producing histologic features of graft versus host disease. J Amer Acad Der- murol 1993; 2 9 (2 Pt 2) 325

Bilgrami S, Fallon BG*. 'Francis Hosp & Med Ctr, Hematol Oncol Sect, Hartford, Ct 06105, USA. Chemotherapy-induced nausea and vomiting: Easing patients fear and discomfort with effective antie- metic regimens. PosrgrudMed 1993; 9 4 (5) 55

Binmoeller KB, Harris AG*, Hastier P, Dumas R, Delmont JP. *Ce- dars Sinai Med Ctr, Dept Med, Div Clin Pharmacol, 8700 Beverly Hills Blvd, MGB 1102, Los Angeles, Ca 90048, USA. Octreotide and ERCP-induced pancreatitis - Beneficial or harmful? (Letter). Amer J Gasrroenrerol 1993; 88: (8) 1291

Boumpas DT, Austin HA, Vaughan EM, Yarboro CH, Klippel JH, Balow JE. NIDDK, Kidney Dis Sect, Bldg 10, Rm 3N-112, Be- thesda, Md 20892, USA. Risk for sustained amenorrhea in patients with systemic lupus erythematosus receiving intermittent pulse cyclophosphamide therapy. Ann Inrern Med 1993; 119 (5 ) 366

Bourgeois H, Perault MC*, Raudraynier P, Favre-Liere S, Daban A, Vandel B. 'CHU Miletrie, Ctr Reg Pharmacovigilance, F-86021 Poitiers, France. 5-Fluorouracil cardiotoxicity - Clinical tables about 4 cases and preventive proposition (French, English Ab- stract). Therupie 1993; 48: (3) 255

Brandis M, Van der Hardt K, Zimmerhackl RB, Mohrmann M, Leiti- tis J. Albert Ludwigs Univ, Kinderklin, Mathildenstr 1, D-79104 Freiburg, FRG. Cytostatics: Induced tubular toxicity. Clin Invesri- guror 1993; 71: (10) 855

Brincker H, Christensen BE. Odense Univ Hosp, Dept Hematol, DK- SO00 Odense, Denmark. Acute mucocutaneow toxicity following high dose hydroxyurea. Cancer Chemorher Phurmacol 1993; 32: (6) 496

Carrio I, Lopez-Pousa A, Estorch M, Duncker D, Bema L, Torres G, De Andres L. Hosp Santa Cruz & San Pablo, Dept Nucl Med, Nucl Med Unit, Pare Claret 167, E08025 Barcelona, Spain. Detec- tion of doxorubicin cardiotoxicity in patients with sarcomas by indium-I 1 1-antimyosin monoclonal antibody studies. J Nucl Med

1993; 3 4 (9) 1503 Chasen MR, Falkson G*. *Univ Pretoria, Dept Med Oncol, POB 667,

Pretoria O001, Rep Sth Africa. Leukemia after chemotherapy for cancer. Cancer Eiorherupy 1993; 8 (2) 1 15

Chern S, Dank RP*. *Indiana Univ, Med Ctr, Dept Ophthalmol, 702 Rotary Circle, Indianapolis, In 46202, USA. Retinopathy associated with low dose tamoxifen (Letter). Amer J Ophrhulmol 1993; 116 (3) 372

Cleland BD, Pokomy CS*. *Specialist Med Ctr, Ste 3, 17 Moore St, Liverpol, NSW 2170, Australia. Cyclophosphamide-related hepatotoxicity (Letter). Aurr N Z J Med 1993; 23: (4) 408

Cohen RB, Foss F. NIH, Bethesda, Md 20892, USA. Anesthesia not related to fludarabine toxicity (Reply). Ann Inrern Med 1993; 119

Cvitkovic E, Domenge C, Gandia D. Hop Paul Browse, Dept Med Oncol, 12-14 Ave Paul Vaillant Couturier, F-94804 Villejuif, France. Case report of acquired piritrexim resistance and collateral methotrexate sensitivity in recurrent squamous cell carcinoma of the head and neck. J Not Cuncer Imt 1993; 85: (IS) 1248

Declari F. Osped Civico, Med Klin, CH-6900 Lugano, Switzerland. Rapid occurrence of a multifocal leukencephalopathy during fluorouracil and ranitidine treatment (Letter) (German, English Ab- stract). Deur Med Wochenrchr 1993; 118 (32) 1176

Di Raimondo F, Giustolisi R, Cacciola E, O'Brien S, Kantarjian H, Robertson LB, Keating MJ*. *Univ Texas, MD Anderson Canc Ctr, Dept Hematol, 1515 Holcombe Blvd, Box 38, Houston, Tx 77030, USA. Autoimmune hemolytic anemia in chronic lympho- cytic leukemia patients treated with fludarabine. Leuk Lymphom 1993; 11: (1-2) 63

Even-Sapir E, Barnes DC, Llewellyn CG, Langley GR. Victoria Gen Hosp, Dept Diagnost Radiol, Div Nucl Med, 1278 Tower Rd, Hali- fax, Nova Scotia, Canada B3H 2Y9. Methotrexateinduced neurotoxicity - Appearance on indium-1 1 I-white blood cells, gallium- 67-citrate and thallium-201-chloride scintigraphy. .I Nucl Med 1993; 3 4 (8) 1377

Fjallskog ML, Frii L, Bergh 1. Univ Uppsala, Akad Sjukhuset, Dept Oncol, S-75185 Uppsala, Sweden. Is Cremophor EL, solvent for paclitaxel, cytotoxic? (Letter). Lancer 1993; 342: (8875) 873

Gaudin PB, Hruban RH*, Beschomer WE, Kasper EK, Olson JL, Baughman KL, Hutchins GM. *Johns Hopkins Univ Hosp, Dept Pathol, 600 Nth Wolfe St, Baltimore, Md 21205, USA. Myocardi- tis associated with doxorubicin cardiotoxicity. Amer J Clin Path01 1993; 100: (2) 158

Gericke KR. Univ Calif San Francisco, Div Clin Pharm, 521 Parnas- sus Ave C-152, San Francisco, Ca 94143, USA. Possible interaction between warfarin and fluconazole. Phurmucotherapy 1993; 13: (5) 508

Hajar LR, Kim WS, Nolan GH, Turner S, Raju UR. Univ Michigan, Sch Med, Dept Obstet & Gynecol, 1500 East Med Ctr Dr, Ann Arbor, Mi 48109, USA. Intestinal and pelvic endometriosis presenting as a tumor and associated with tamoxifen therapy - Report of a case. Obster Gynecol 1993; 82: (4 Pt 2) 642

Hawkins MJ. Georgetown Univ, Med Ctr, Vincent T Lombardi Canc Res Ctr, Dept Med, 3800 Reservoir Rd, Washington, DC 20007, USA. Early cancer clinical trials: Safety, numbers, and consent (Editorial). J Nuf Cancer Inst 1993; 85: (20) 1618

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Violi F, Longoni A, Maderna M, Castiglioni C, Balsano F. Univ Roma La Sapienza, Policlin Umberto 1 , Med Clin 1, 1-00161 Rome, Italy. Safety of picotamide, an antiplatelet agent, in an 18 month, double-blind, placebo-controlled, multicenter trial in 2304 patients with peripheral vascular disease. Curr Ther Res 1993; 54:

Zeidman SM, Olivi A. Johns Hopkins Univ Hosp, Dept Neurosurg, Baltimore, Md 21205, USA. Cervical intramedullary hemorrhage as a result of anticoagulant therapy - Presentation. J Spinal Disor- der 1993; 6: ( 5 ) 456

Zelinski S, Richter M, Werning P, Frank G. Stadt Klinikums Braun- schweig, Hen Thorax & Gefasschirurg Klin, Salzdahlumer Str 90, W-3300 Braunschweig, FRG. Incompatibility reactions to protamine - Case Report. Anasthesiol Intensivmedizin 1993; 34 (4) I27

Zoldhelyi P, Webster MWI, Fuster V, Grill DE, Gaspar D, Edwards SJ, Cabot CF, Chesebro JH*. *Massachusetts Gen Hosp, Cardiac Unit, Jackson 1402, 32 Fruit St, Boston, Ma 021 14, USA. Recom- binant hirudin in patients with chronic stable coronary artery disease: Safety, half-life, and effect on coagulation parameters. Circu- lafion 1993; 88: (5 Part 1) 2015

5 (3) 180

( I ) 1 1 1

10 NEUROREGULATOR-BLOCKING AGENTS

Aguglia E, Casacchia M, Cassano GB, Faravelli C, Ferrari G, Gior- dano P, Pancheri P, Ravizra L, Trabucchi M, Bolino F era/. Univ Trieste, 1-34127 Trieste, Italy. Double-blind study of the efficacy and safety of sertraline versus fluoxetine in major depression. Inr Clin Psyhophaimacol 1993; 8: (3) 197

Beasley CM, Masica DN, Heiligenstein JH, Wheadon DE, Zerbe RL. Eli Lilly & Co, Lilly Res Lab, Div Psychopharmacol, Lilly Corp Ctr 2128, Indianapolis, In 46285, USA. Possible monoamine oxidase inhibitorkotonin uptake inhibitor interaction: Fluoxetine clinical data and preclinical findings. J Clin Psychopharmacol 1993; lk (5) 312

Bergstrom RF, Beasley CM, Levy NB, Blumenfield M, Lemberger L.

Wishard Mem Hosp, Eli Lilly & Co, Lilly Lab Clin Res, I001 West loth St, Indianapolis, In 46202, USA. The effects of renal and hepatic disease on the pharmacokinetics, renal tolerance, and risk benefit profile of fluoxetine. In? Clin Psychopharmacol 1993; 8: (4) 261

Bhatara VS, Bandettini F. Univ Sth Dakota, Hlth Ctr Children, Sioux Falls, SD, USA. Serotonin syndrome and drug interactions. Clin Pharmacol Ther 1993; 54: (2) 230

Bjorksten KS, Walinder J. Linkoping Univ Hosp, Dept Psychiat, S- 581 85 Linkoping, Sweden. Does mianserin induce involuntary movements in brain damaged patients? Inf Clin Psyhopharmacol 1993; 8: (3) 203

Bronzo MR, Stahl SM. Address not available. Galactorrhea induced by sertraline (Letter). Amer JPsychiat 1993; 150 (8) 1269

Buist A, Norman TR, Dennerstein L. Univ Melbourne, Key Ctr Womens Hlth SOC, Parkville, Vic 3052, Australia. Mianserin in breast milk (Letter). Brit J Clin Pharmacol 1993; 36: (2) 133

Ceccherini-Nelli A, Guidi L. Eli Lilly Italia, via Gramsci 731-733, Sesto Fiorentino, 1-50019 Florence, Italy. Fluoxetine: The relationship between response, adverse events, and plasma concentrations in the treatment of bulimia nervosa. Int CIin Psychopharmacol 1993; 8: (4) 311

Chen M, Tanner A, Gallo-Torres H. US FDA, Rockville, Md 20857, USA. Anaphylactoid-anaphylactic reactions associated with ondansetron (Letter). Ann Infern Med 1993; 119 (8) 862

Coutellier A, Pelletier S, Ekert P, Hauw JJ, Soubrie C, Herson S. Hop La Pitie Salpetriere, Serv Med Interne, 47 Blvd Hop, F-75651 Paris 13, France. Inflammatory myopathy during ranitidine therapy (Letter). JRhewnatol1993; 2 0 (8) 1453

Crane JK, Shih HT. Univ Texas, Hlth Sci Ctr, Houston, Tx 77225, USA. Syncope and cardiac arrhythmia due to interaction between itraconazole and terfenadine. Amer J Med 1993; 9 5 (4) 445

Crews JR, Potts NLS, Schreiber J, Lipper S. Address not available. Hyponatremia in a patient treated with sertraline (Letter). Amer J Pychiat 1993; 150 (10) 1564

Dursun SM, Mathew VM, Reveley MA. Univ Leicester, Fac Med, Dept Psychiaf Leicester LE2 7LX, England. Toxic serotonin syndrome after fluoxetine plus carbamazepine (Letter). Lancet 1993; 342: (8868) 442

Feinberg M. Univ Maryland, Sch Pediat, Ctr Study Pharm & Thera- peut Elderly, Elder Hlth Program, Baltimore, Md 21201, USA. The problems of anticholinergic adverse effects in older patients. Drug Aging 1993; 3: (4) 335

Feldman M. Vet Affairs Med Ctr, Med Serv I 1 1, Dept Internal Med, 4500 Sth Lancaster Rd, Dallas, Tx 75216, USA. Pros and cons of over-the-counter availability of histamine(2)-receptor antagonists (Commentary). Arch Intern Med 1993; 153: (21) 2415

Gupta S, Freimer M, Popli A. Address not available. Paradoxical sedation with sertraline (Letter). Amer J Psychiar 1993, 150: (9) 1427

Heiligenstein JH, Beasley CM, Potvin JH. Eli Lilly & Co, Lilly Res Lab, Div Psychopharmacol, Lilly Corp Ctr 2128, Indianapolis, In 46285, USA. Fluoxetine not associated with increased aggression in controlled clinical trials. Int CIin Psychopharmacol 1993; 8: (4) 277

Kleine MW, Ertl D. Practice Gen Med & Allergiol, Egenhofenstrasse 18, W-8033 Planegg, FRG. Comparative trial in volunteers to investigate possible ethanol-ranitidine interaction. Ann Pharmacorher

Lazar0 M, Compaired JA, De la Hoz B, Igea JM, Marcos C, Davila I, Losada E. Alergoasma SL, C Tor0 2541, E-37002 Salamanca, Spain. Anaphylactic reaction to ranitidine. Allergy 1993; 48: ( 5 ) 385

Lester BM, Cucca J, Andreozzi L, Flanagan P, Oh W. Brown Univ, Emma Pendleton Bradley Hosp, Sch Med, Dept Psychiat, 101 1 Vet Mem Pkwy, East Providence, RI 02915, USA. Case study: Possi- ble association between fluoxetine hydrochloride and colic in an

1993; 27: (7-8) 841


infant. J Amer Acud Child Adolesc Psychiut 1993; 32: (6) 1253 Lutsky BN, Klose P, Melon J, Menardo JL, Molkhou P, Ronchetti R,

Suonpaa J, Wahn U, Wessel F. Sch Plough Corp, Res Inst, Kenil- worth, NJ 07033, USA. A comparative study of the efficacy and safety of loratadine syrup and terfenadine suspension in the treatment of 3-6 year old children with seasonal allergic rhinitis. CIin Ther 1993; 15: (5) 855

Muly EC, McDonald W, Steffens D, Book S. Address not available. Serotonin syndrome produced by a combination of fluoxetine and lithium (Letter). Amer JPsychiut 1993; 150: (10) 1565

Nahum E, Reish 0, Naor N, Merlob P. Tel Aviv Univ, Beilinson Med Ctr, Dept Neonatol, IL-49100 Petah Tiqwa, Israel. Ranitidine induced bradycardia in a noenate: A first report. Eur J Pediuf 1993; 152: (1 1) 933

Oliver M, Stenn PG. Univ Westem Ontario, Univ Hosp, Dept Psy- chiat, London, Ontario, Canada N6A 5A5. Is there a risk for de- pendency with therapeutic doses of dimenhydrinate? (Letter). Psy- chosomutics 1993; 3 4 (5) 459

Pande AC, Sayler ME. Eli Lilly & Co, Lilly Res Lab, Lilly Corp Ctr, DC2128, Indianapolis, In 46285, USA. Adverse events and treatment discontinuations in fluoxetine clinical trials. Int CIin Psycho- pharmucoI1993; 8: (4) 267

Parker G. Univ New Sth Wales, Randwick, NSW 2031, Australia. Fluoxetine - Delayed half life and an adverse event (Letter). Med J Australia 1993; 159 ( 5 ) 360

Powell JA, Maycock EJ. Christchurch Hosp, Dept Anaesthesia, Pri- vate Bag 4710, Christchurch, New Zealand. Anaphylactoid reaction to ranitidine in an obstetric patient (Case Report). Anuesth In- tensive Cure 1993; 21: (5) 702

Rapport DJ, Calabrese JR. Univ Hosp Cleveland, Cleveland, Oh 44106, USA. Tolerance to fluoxetine (Letter). J Clin Pychophur- mucol 1993; 13: (5) 361

Sargent AI, Deppe SA, Chan FA. Mercy Hosp Pittsburgh, Dept Pharm, 1400 Locust St, Pittsburgh, Pa 15219, USA. Seizure associated with ondansetron. CIin Pharmacy 1993; 12: ( 8 ) 613

Schmidt M, Sorbe B, Hogberg T, Himmelmann A, Raisanen I, Stock- meyer M, DebNijn KM. Univ Hosp, Gynecol Oncol, Uppsala, Sweden. Efficacy and tolerability of tropisetron and dexamethasone in the control of nausea and vomiting induced by cisplatin. Ann Oncol 1993; 4 (Suppl3) S31

Spencer MJ. 910 East Ohio Ave, Ste 103, Escondido, Ca 92025, USA. Fluoxetine hydrochloride (Prozac) toxicity in a neonate. Pe- diutrics 1993; 92: (5) 721

Spivey KM, Wait CM. Horton Gen Hosp, Banbury OX16 9AL, Oxon, England. Perioperative seizures and fluvoxamine (Letter). Brit JAnuesth 1993; 71: (2) 321

Tidswell P, DAssis-Fonseca A. Pinderfelds Hosp, Wakefield WFI 4DG, England. Generalised seizure due to terfenadine (Drug Point). Brit Med J 1993; 307: (6898) 241

Tidswell P, DAssis-Fonseca AE. Pinderfelds Gen Hosp, Wakefield WFI 4DG, England. Generalised seizure due to terfenadine (Let- ter). Brit Med J 1993; 307: (6906) 736

Wolkenstein P, Revuz J, Diehl JL, Langeron 0, Roupie E, Machet L. Univ Paris 12, Hop Henri Mondor, Dept Dermatol, F-94010 Creteil, France. Toxic epidermal necrolysis after fluvoxamine (Let- ter). Lancet 1993; 342: (8866) 304

Woolfrey S, Gammack NS, Dewar MS, Brown PJE. Wansbeck Gen Hosp, Ashington NE63 9JJ, Northumberland, England. Fluoxetine- warfarin interaction (Drug Point). Brit Med J 1993; 307: (6898) 24 1

1 1 DERMATOLOGICAL AGENTS

C o r n M, Roveggio C, Virgili A. Univ Ferrara, via Savonarola 9, 1-44100 Ferrara, Italy. Allergic contact dermatitis from bufexamac cream. Confucf Dermafifis 1993; 29: (4) 219

Duhra P, Charles-Holmes R. Milton Keynes Dist Gen Hosp, Milton

Keynes MK6 5LD, England. Contact sensitivity to N-A@ dressing (Reply). Contact Dermatitis 1993; 29: ( I ) 52

Higgins EM, Pembroke AC. Univ London Kings Colt Hosp, London SE5 8RX, England. Sticky palms - An unusual side-effect of etreti- nate therapy (Letter). CIin Exp Dermufol 1993; 18: (4) 389

Hughes RA. Charing Cross Hosp, Dept Rheumatol, Ground Floor E Wing, Fulham Palace Rd, London W6 8RF, England. Arthritis pre- cipitated by isotretinoin treatment for acne vulgaris. J Rheumutol 1993; 2 0 (7) 1241

Martinez FV, Badas AJ, Goitia JFG. Hosp Amara, Secc Alergia, Paseo Dr Beguiristain 107, E-20014 San Sebastian, Spain. Contact dermatitis from thioxolone. Contuct Dermufitis 1993; 29: (2) 96

Massone L, Anonide A, Borghi S, Usiglio D. Galliera Hosp, Dept Dermatol, Mura Cappuccine 14,1-16128 Genoa, Italy. Contact dermatitis of the eyelids from resorcinol in an ophthalmic ointment. Contuct Dermatitis 1993; 2 9 ( I ) 49

Sherrell AL. Johnson & Johnson Med Ltd, Airebank Mill, Skipton BD23 3RX, England. Contact sensitivity to N-A@ dressing (Let- ter). Contucf Dermatitis 1993; 29: ( I ) 52

Tabar AI, Muro MD, Quirce S, Olaguibel JM. Virgen Camino Hosp, Allergol Sect, Plaza Paz S-N, E-31004 Pamplona, Spain. Contact dermatitis due to sensitization to lactic acid and castor oil in a wart remover solution. Contact Dermatitis 1993; 2 9 ( I ) 49

12 IMMUNOSUPPRESSIVE AGENTS

Al-Awadhi A, Dale P, McKendry RJR*. *Univ Ottawa, Ottawa Gen Hosp, Rheumat Dis Unit, 501 Smyth Rd, Rm LM-10, Ottawa, On- tario, Canada KIH 8L6. Pancytopenia associated with low dose methotrexate therapy - A regional survey. J Rheumutol 1993; 2 0

Aria JM, Morton KA*, Albro JE, Patch GG, Valdvia S, Greenberg HE, Christian PE, Datz FL. *Vet Adm Med Ctr, Nucl Med Sect, 500 Foothill Blvd, Salt Lake City, Ut 84148, USA. Comparison of methods for identifying early methotrexate-induced hepatotoxicity in patients with rheumatoid arthritis. J Nucl Med 1993; 3 4 (1 1) 1905

Bach JF, Fracchia GN, Chatenoud L. Hop Necker Enfants Malad, INSERM, U25, F-75730 Paris 15, France. Safety and efficacy of therapeutic monoclonal antibodies in clinical therapy. Immunol To- dny 1993; 14: (9) 421

Bardin PG, Fraenkel DJ, Beasley RW. Univ Southampton, Southamp- ton Gen Hosp, Immunopharmacol Grp, Level D, Ctr Block, Tre- mona Rd, Southampton SO9 4XY, England. Methotrexate in asthma - A safety perspective (Commentary). Drug Safe@ 1993; 9 (3) 151

Bemabeu M, Krupp P, Wiskott E. Sandoz Ltd, Dept Med Informat, CH-4002 Basel, Switzerland. Long term safety of cyclosporine in renal transplant recipients - Worldwide experience. Trumplunt Proc 1993; 2 5 (4) 17

Bilik R, Superina RA, Hu X. Hosp Sick Children, Dept Surg, 555 Univ Ave, Toronto, Ontario, Canada M5G 1x8. Long term effect of cyclosporine on renal function in children after liver transplantation. Trunsplunt Proc 1993; 25: (4) 2578

Bordet JC, De Lorgeril M, Durbin S, Boissonnat P, Renaud S, Dureau G, Dechavanne M. Inst Pasteur Lyon, Lyon, France. Systemic but not renal production of prostacyclin is highly reduced in cyclosporin-treated hem transplant recipients. Amer J Cardiol 1993; 72: (5) 486

Bowen JRC, Sahi S. BMH Rinteln, BFPO 29, Rinteln, FRG. Cy- closporin-induced colitis. Brit Med J 1993; 307: (6902) 484

Carvallo A, Wolff C, Armas R, Villanueva P, Donoso G, Naquira N, L o b G, Rojas C, Domic H. Univ Chile, Fac Med, Dept Med, Campus Occidente, Casilla 33052, Santiago, Chile. Efficacy and hepatotoxic effects of methotrexate in rheumatoid arthritis (Span- ish, English Abstract). Rev Med Chile 1993; 121: (7) 777

Casserly CM, Stange KC, Chren MM*. *Vet Affairs Med Ctr, Dept

(7) 1121


Dermatol, 10701 East Blvd, Cleveland, Oh 44106, USA. Severe megaloblastic anemia in a patient receiving low-dose methotrexate for psoriasis. J Amer Acad Dermatol 1993; 29: (3) 477

Connell WR, Kamm MA*, Ritchie JK, Lennard-Jones JE. *St Marks Hosp, City Rd, London EClV 2PS, England. Bone marrow toxicity caused by azathioprine in inflammatory bowel disease - 27 years of experience. Cur 1993; 34 (8) 1081

Edwards BD, Ballardie FW, Moms DJ, ODriscoll JB, Chalmers RIG. Manchester Royal Infirm, Dept Med, M3 Records, Oxford Rd, Manchester MI3 9WL, England. Should atypical lymphocytes and plasma cells in well patients with psoriasis on cyclosporin cause concern? (Letter). Brir J Dermarol 1993; 129: (2) 222

Emilia G, Messora C. Univ Modena, Med Clin 2, 1-41 100 Modena, Italy. Interaction between cyclosporin and chlorambucil (Letter). Eur J Haematol 1993,51: (3) 179

Finielz P, Gendoo Z, Chuet C, Guiserix J. Ctr Hosp Gen St Pierre Le Tampon, Dept Nephrol, Sew Med F, BP 350, F-97448 St Pierre, France. Interaction between cyclosporin and chloroquine (Letter). Nephron 1993; 65: (2) 333

Gossmann J, Kachel HG, Schoeppe W, Scheuermann EH. Univ Frankfurt, Zentrum Inneren Med Klinikum, Nephrol Abt, W-6000 Frankfurt, FRG. Anemia in renal transplant recipients caused by concomitant therapy with azathioprine and angiotensin-converting enzyme inhibitors. Transplanrarion 1993; 56: (3) 585

Hamada T, Kumashiro R, Koga Y, Hino T, Furudera S, Sakisaka S, Sata M, Tanikawa K, Taguchi J, Kage M. Kurume Univ, Dept Internal Med 2, 67 Asahi machi, Kurume, Fukuoka 830, Japan. Fatal acute hepatitis B virus infection while receiving immunosup- pressants after renal transplantation (Case Report). Internal Med 1993; 32: (7) 547

Hess AD, Fischer AC, Horwitz LR, Laulis MK. Johns Hopkins Univ, Ctr Oncol 3127, 600 Nth Wolfe St, Baltimore, Md 21287, USA. Cyclosporine-induced autoimmunity: Critical role of autoregulation in the prevention of major histocompatibility class 11-dependent autoaggression. Transplant f roc 1993; 2 5 (5) 281 1

Humphreys TR, Leyden JJ. Hosp Univ Penn, Dept Dermatol, 2 Gates, 3400 Spruce St, Philadelphia, Pa 19104, USA. Acute reversible central nervous system toxicity associated with low-dose oral cyclosporine therapy. J Amer Acad Dermarol 1993; 29: (3) 490

Jahan-Souz F. Address not available. Potentiation of cyclosporine nephrotoxicity by nafcillin in lung transplant recipients (Tramplan- tarion 1993, 55 1045) (Correction). Tramplantarion 1993; 56: (1) u1

Jones JJ, Ashworth J. Univ Liverpool, Royal Liverpool Hosp, Dept Pharm, Liverpool L69 3BX, England. Azathioprine-induced shock in dermatology patients. J Amer Acad Dermarol 1993; 29: (5) 795

Kaye D, Thompson J, Jennings G, Esler M. Alfred Hosp, Alfred Baker Med Unit, Commercial Rd, Prahran, Vic 3181, Australia. Cyclosporine therapy after cardiac transplantation causes hypertension and renal vasoconstriction without sympathetic activation. Cir- culation 1993; 88: (3) 1101

Kerstens PJSM, Stolk JN, Hilbrands LB, Vandeputte LBA, Deabreu RA, Boerbooms AMT. Univ Hosp Nijmegen, Dept Rheumatol, POB 9101, 6500 HB Nijmegen, The Netherlands. 5-Nucleotidase and azathioprine-related bone marrow toxicity (Letter). Lancer 1993; 342: (8881) 1245

Kreis H. Hop Necker Enfants Malad, Sew Transplantat, 161 rue Se- vres, F-75743 Paris 15, France. Adverse events associated with OKT3 immunosuppression in the prevention or treatment of allograft rejection. CIin Tramplanr 1993; 7: (4) 431

Lien YHH, Hunt KR, Siskind MS, Zukoski C. Univ Arizona, Arizona Hlth Sci Ctr, Dept Med, Tucson, Az 85724, SA. Association of cyclosporin A with acquired cystic kidney disease of the native kidneys in renal transplant recipients. Kidney Inr 1993; 44: (3) 613

Mampaso F, Sanchez-Madrid F, Marcen R, Molina A, Pascual J, Bricio T, Martin A, Alvarez V. Hosp Ramon y Cajal, Dept Pathol, Carretera Colmenar Km 9100, E-28034 Madrid, Spain. Expression of adhesion molecules in allograft renal dysfunction: A distinct di-

agnostic pattern in rejection and cyclosporine nephrotoxicity. Tramplanrarion 1993; 56: (3) 687

Min DI, Fallo SA. Univ Iowa, Coll Pharm, 2267 Quadrangle, Iowa City, Ia 52242, USA. Encephalopathy associated with muromonab CD3. Clin Phurmaq 1993; 12: (8) 610

Morris LF, Harrod MJ, Menter MA*, Silverman AK. 'Baylor Univ, Med Ctr, Baylor Psoriasis Ctr, 3600 Gaston Ave, Ste 656 wad19 Tower, Dallas, Tx 75246, USA. Methotrexate and reproduction in men: Case report and recommendations. J Amer Acad Dermatol 1993; 2 9 (5 Part 2) 913

Murphy EA, Moms AJ, Walker E, Lee FD, Sturrock RD. Glasgow Royal Infirm, Dept Med, Glasgow G31 2ER, Scotland. Cyclospor- ine A induced colitis and acquired selective IgA deficiency in a patient with juvenile chronic arthritis. J Rheumnrol 1993; 2 0 (8) 1397

Nachbar F, Stolz W, Volkenandt M, Meurer M. Univ Munich, Der- matol Klin & Poliklin, Dept Dematol, Frauenlobstr 9-1 1, W-goo0 Munich 2, FRG. Squamous cell carcinoma in localized sclero- derma following immunosuppressive therapy with azathiorpine. Acra Dermato-Venereoll993; 73: (3) 217

Paul A, Levy GA, Greig PD*. *Toronto Hosp, Dept Surg, 200 Elisa- beth St, GW 3-538, Toronto, Ontario, Canada M5G 2C4. Balanc- ing cyclosporine A nephrotoxicity and rejection late after adult liver transplantation. Tramplant Proc 1993; 2 5 (4) 2664

Piepkorn M, Kumasaka B, Krieger JN, Burmer GC. Univ Washing- ton, Sch Med, Dept Med Dennatol, Div Dermatol, Rm-14 HIth Sci, Seattle, Wa 98195, USA. Development of human papilloma- virus associated Buschke-Lowenstein penile carcinoma during cyclosporine therapy for generalized pustular psoriasis. J Amer Acad Dermatol 1993; 2 9 (2 Pt 2) 321

Pointud P, Prudat M, Peron JM. Ctr Hosp Montlucon, Dept Rheuma- to1 & Internal Med, F-03109 Montlucon, France. Acute leukemia after low dose methotrexate therapy in a patient with rheumatoid arthritis. JRhewnarol 1993; 2 0 (7) 1215

Ramsey-Goldman R, Mientus JM, Kutzer JE, Mulvihill JJ, Medsger TA. Northwestem Univ, Ward 3-315, 303 East Chicago Ave, Chi- cago, II 6061 1, USA. Pregnancy outcome in women with systemic lupus erythematosus treated with immunodepressive drugs. J Rheu- matol 1993; 2 0 (7) 1 152

Richter A, Beideck S, Bender W, Frosch PJ*. *Univ Witten Her- decke, Stadt Klin, Lehrstuhl Dermatol, Haut Klin, Beurhausstr 40, D-44137 Dortmund, FRG. Epidermal cysts and follicular eruptions with cyclosporine A (German, English Abstract). Houtrat 1993; 44: (8) 521

Shaheen FAM, Al-Sulaiman MH, Al-Khader AA*. *Riyadh Armed Forces Hosp, Dept Nephrol, POB 7897, Riyadh 11 159, Saudi Ara- bia. Long-term nephrotoxicity after exposure to cyclosporine in utero. Transplantation 1993; 56: ( I ) 224

Superina R, Acal L, Bilik R, Zaki A. Univ Toronto, Hosp Sick Chil- dren, Dept Surg, Liver Transplant Program, 555 Univ Ave, Toronto, Ontario, Canada MSG 1x8. Growth in children aRer liver transplantation on cyclosporine alone or in combination with low dose azathioprine. Tramplant Proc 1993; 25: (4) 2580

Van Leeuwen ML, Van Gelder T, Van Gemert HMA, Weimar W. Univ Hosp Rotterdam, Dept Internal Me4 Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands. Critical blindness due to cyclosporin. Nerh JMed 1993; 43: (1-2) 69

Ventura HO, Milani RV, Lavie CJ, Smart FW, Stapleton DD, Toups TS, Price HL. Alton Ochsner Med Fdn & Ochsner Clin, Dept In- ternal Med, Cardiol Sect, 1514 Jefferson Highway, New Orleans, La 70121, USA. Cyclosporine-induced hypertension: Efficacy of 0 3 fatty acids in patients after cardiac transplantation. Circulation 1993; 88: (5 Part 2) 281

Vinot 0, Cochat P*, Dubourg-Derain L, Bouvier R, Vial T, Philippe N. *Hop Edouard Herriot, Unite Nephrol Pediat, Sen, Pharmaco- toxicovigilance, F-69437 Lyon 03, France. Jaundice associated with concomitant use of norethandrolone and cyclosporine. Trans- plantation 1993; 56: (2) 470


Waser M, Maggiorini M, Binswanger U, Keusch G, Carrel T, Von Segesser L, Gallino A*, Turina M. 'Univ Hosp Zurich, Dept Med, Div Cardiol, Ramktr 100, CH-8091 Zurich, Switzerland. Irreversi- bility of cyclosporine-induced renal function impairment in heart transplant recipients. JHeart Lung Transplant 1993; 12: (5) 846

Wilson BE, Parsonnet J. 3820 Pk Blvd, Apt 14, Palo Alto, Ca 94306, USA. Azathioprine hypersensitivity mimicking sepsis in a patient with Crohn's disease. Clin Infect Dis 1993; 17: (5) 940

Wodzig KWH, Majoor GD, Tiebosch ATMG, De Heer E, Vriesman PJCV. Univ Limburg, Dept Immunol, POB 616, 6200 MD Maas- trict, The Netherlands. Malignant neoplasms in cyclosporine-induced autoimmunity. Trunsplunt Proc 1993; 2 5 (5) 2816

Wodzig KWH, Majoor GD, Vriesman PJCV. Univ Limburg, Dept Immunol, POB 616, 6200 MD Maastrict, The Netherlands. Kinet- ics of inducdeffector cell generation in the thymus in cyclosporine- induced autoimmunity. Trunsplunt Proc 1993; 2 5 (5) 2819

$'\g, 13 AUTONOMIC AGENTS

Austin SM, Al-Hayek A, Comianos M, Tamulonis DJ. St Elizabeth Hosp, Dept Internal Med, 1044 Belmont Ave, POB 1790, Young- stown, Oh 44501, USA. Mitral valve disease associated with long- term ergotamine use. Southern Med J 1993; 86: (1 0) 1 179

Brodsky M, Kamenker E, Orlov M, Allen B. Univ Calif Irvine, Irvine Med Ctr, Orange, Ca 92668, USA. Cardiac effect of prolonged p-blocker therapy for migraine (Letter). J Am Med Assn 1993; 270 (7) 880

Buikema H, Grandjean JG. Univ Groningen, Dept Pharmacol, Clin Pharmacol, 9713 BZ Groningen, The Netherlands. Potentiation of a-adrenoceptor-mediated vasoconstriction by sumatriptan (Letter). Lancet 1993; 342: (8879) 1121

Carey M. St James Hosp, Dept Anaesthesia, James St, POB 580, Dublin 8, Rep Ireland. Adverse cardiovascular sequelae of er- gometrine. Brit J Obstet Gynuecoll993; 100: (9) 865

Cavanah DK, Ballas ZK*. *Univ Iowa Hosp & Clin, Dept Internal Med, 200 Hawkins Dr, Iowa City, Ia 52242, USA. Pseudoephe- drine reaction presenting as recurrent toxic shock syndrome. Ann Intern Med 1993; 119 (4) 302

Cusano F, Lucian0 S, Capozzi M, Verrilli DA. G Rummo Gen Hosp, Div Dermatol, via Angelo 1, 1-82100 Benevento, Italy. Contact dermatitis from pilocarpine. Contact Dermutitis 1993; 2 9 (2) 99

Cutler NR, Sramek JJ. Calif Clin Trials, 8500 Wilshire Blvd, 7th Floor, Beverly Hills, Ca 9021 1, USA. Poor tolerability of MK-458 (Letter). Arch Neurol 1993; 5 0 (9) 896

Desai UR, Sudhamathi K, Natarajan S. Henry Ford Hosp, Dept Ophthalmol, 2799 W Grand Blvd, Detroit, Mi 48202, USA. Intra- venous epinephrine and acute macular neuroretinopathy (Case Re- port). Arch Ophthulmol 1993; 111: (8) 1026

Escrig MG, Pareja FB, Ponsati JF. Hosp 12 Octubre, Sew Neurol, Madrid, Spain. Facial edema as an adverse effect to pergolide (Let- ter) (Spanish, English Abstract). Med Clin 1993; 101: (7) 275

Farm G. Natl Inst Occupat Hlth, Dept Occupat Dermatol, S-10401 Stockholm, Sweden. Contact allergy to nicotine from a nicotine patch. Contact Dermatitis 1993; 2 9 (4) 214

Grimmett MR, Williams KK, Brmker G, Edelhauser HF*. *Emory Univ, Eye Ctr, 1327 Clifton Rd NE, Atlanta, Ga 30322, USA. Cor- neal edema after miochol (Letter). Amer J Ophrhulmol 1993; 116: (2) 236

Hillis WS, MacIntyre PD. Western Infirm & Associated Hosp, Gardi- ner Inst, Dept Med & Therapeut, Glasgow G11 6NT, Scotland. Sumatriptan and chest pain (Letter). h c e t 1993; 342: (8872) 683

Hudgens DR, Conradi SE*. '171 Ashley Ave, Charleston, SC 29425, USA. Sudden death associated with terbutaline sulfate administration. Amer J Obstet & Gynecoll993; 169 (1) 120

Ingrams GJ, Morgan FB. Kidderminster Gen Hosp, Kidderminster DYI 1 6RJ, England. Transcutaneous overdose of terbutaline. Brit Med J 1993; 307: (6902) 484

Jackson M. Univ Nottingham Hosp, Queens Med Ctr, Dept Neurol, Nottingham NG7 2UH, England. Cerebral arterial narrowing with nicotine patch (Letter). Lnncer 1993; 342: (8865) 236

Martinez FV, Badas AJ, Goitia JFG, Aguirre I. Hosp Amara, Secc Alergol, Paseo Dr Beguiristain 107, E-20014 San Sebastian, Spain. Generalized dermatitis due to oral ephedrine. Contact Dermatitis 1993; 29: (4) 215

Nemecek D, Rastogi-Cruz D, Csernansky JG. Address not available. Atropinism may precipitate neuroleptic malignant syndrome daring treatment with clozapine (Letter). Amer JPsychiur 1993; 150 (10) 1561

Offidani C, Ottaviano V, Chiarotti M. Catholic Univ Sacred Heart, Inst Med Legale & Assicuraz, Largo F Vito 1, 1-00168 Rome, It- aly. Fatal case of bamifylline intoxication. Amer J Foren Med Path 1993; 14: (3) 244

Ottervanger JP, Van Witsen TB, Valkenburg HA, Stricker BHC'. 'Netherlands Ctr Monitoring Adverse Drug React, POB 5406, 2280 HK Rijswijk, The Netherlands. Postmarketing study of cardiovascular adverse reactions associated with sumatriptan. Brit Med J 1993; 307: (6913) 1185

Peter SA, Auk A, Jeansimon ML. St Marys Hosp Brooklyn, Dept Med, 170 Buffalo Ave, Brooklyn, NY 11213, USA. Bromo- criptine-induced schizophrenia (Case Report). J Natl Med Assn 1993; 85: (9) 700

Rockwell KA. Univ Wisconsin Hosp & Clin, Dept Pharm, 600 High- land Ave, Rm F6 133, Madison, Wi 53792, USA. Potential interaction between niacin and transdermal nicotine (Letter). Ann Phar- mcother 1993; 27: (10) 1283

Safran AB, Simona F, Sansonetti A, Pometta D, James R. Geneva Univ Hosp, Dept Ophthalmol, CH-1211 Geneva 4, Switzerland. Topical timolol maleate might adversely affect serum lipoproteins. Int Ophthulmol 1993; 17: (2) 109

Shorr RI, Ray WA, Daugherty JR, Griffin MR. Vanderbilt Univ, Med Ctr, Sch Med, Dept Prevent Med, Div Pharmacoepidemiol, Nash- ville, Tn 37232, USA. Reserpine reconsidered - No association with serious peptic ulcer disease, J Gen Intern Med 1993; 8: (9) 510

Sun KO. Tung Wah Hosp, Dept Anesthet, Waterloo Rd, Kowloon, Hong Kong. Bronchospasm after esmolol and neostigmine. Anesth Intensive Care 1993; 21: (4) 457

Tfelt-Hansen P, Ferrari MD, Olesen J. Bispebjerg Hosp, Dept Neurol, DK-2400 Copenhagen, Denmark. Association between sumatriptan and stroke (Letter). Lancet 1993; 342: (8866) 303

Varriale P, Ramaprasad S. New York Med Coll, Cabrini Med Ctr, Div Cardiol, 227 East 19th St, New York, NY 10003, USA. Ami- nophylline induced atrial fibrillation. Pacing Clin Electrophysiol 1993; 16: (10) 1953

Vincenzi C, Tosti A, Cirone M, Guarrera M, Cusano F. Univ Bolo- gna, Dept Dermatol, via Massarenti 1, 1-40138 Bologna, Italy. Al- lergic contact dermatitis from transdermal nicotine systems. Con- tact Dermatitis 1993, 29: (2) 104

Wheeler SD. 8950 N Kendall Dr, #501, Miami, F1 33176, USA. Di- hydroergotamine local reactions reduced by normal saline. Neurol- ogy 1993; 43: (9) 1852

Wilkinson SM, Kingston TP, Beck MH. Skin Hosp, Chapel St, Sal- ford M60 9EP, England. Allergic contact dermatitis from phenyle- phrine in a rectal ointment. Contact Dermatitis 1993; 2 9 (2) 100

14 RESPIRATORY SYSTEM AGENTS

Bourbeau J, Delfino R, Emst P*. *McGill Univ, Dept Epidemiol & Biostat, Resp Epidemiol Unit, 11 10 Pine Ave W, Montreal, Que- bec, Canada H3A 1A3. Tracheal size is a determinant of the bron- choconstructive response to inhaled methacholine. Eur Resp f 1993; 6 (7) 991

Britton J. City Hosp Nottingham, Resp Med Unit, Nottingham NG5 IPD, England. Tolerance to p-agonists in asthma therapy (Com-


menmy). Lancer 1993; 342: (8875) 818 Chin C, Choy M*. Wniv Calif Davis, Sacramento Med Ctr, Davis

Med Ctr, Div Pediat Cardiol, 2516 Stockton Blvd, Sacramento, Ca 95817, USA. Cardiomyopathy induced by phenylpropanolamine. J Pediat 1993; 123: (5) 825

Clark B. Fisow plc, Div Pharmaceut, Bakewell Rd, Loughborough LEI 1 ORH, England. General pharmacology, pharmacokinetics, and toxicology of nedocromil sodium. J Allerg CIin Immunol 1993; 92: (1) 200

Del Bufalo C, Fasano L, Fabbn M, Quarta CC, Gunella G*. Wniv Bologna, Cattedra Fisiopathol, 1-40126 Bologna, Italy. Efficacy and tolerability of nedocromil sodium versus placebo in chronic reversible obstructive airways disease. J Invest Allerg CIin Immu- no1 1993; J: (3) 136

Dorow P, Aurich R, Pekold U. DRK Krankenhaus Mark Branden- burg, Innere Abt Pneumol 1, Drontheimerstr 39-40, D-13359 Ber- lin, FRG. Efficacy and tolerability of azelastine nasal spray in patients with allergic rhinitis compared to placebo and budesonide. Ameim-Forsch-Drug Res 1993; 43-2 (8) 909

Dwyer CM, Dick D. Stobhill Gen Hosp, Dept Dermatol, Glasgow G21 3UW, Scotland. Fixed drug eruption caused by diphenhy- dramine. J Amer Acad DematoI1993; 2 9 (3) 496

Ernst P, Habbick B, Suissa S, Hemmelgam B, Cockcroft D, Buist AS, HorWik RI, McNutt M, Spitzer WO. McGill Univ, Montreal Gen Hosp, Dept Epidemiol & Biostat, Resp Epidemiol Unit, Mont- real, Quebec, Canada H3A 1Al. Is the association between inhaled p-agonist use and lifethreatening asthma because of confounding by severity? Amer Rev Resp Dis 1993; 148: (1) 75

Finnerty JP, Howarth PH. Southampton Gen Hosp, Fac Med, Level D, Ctr Blk, Tremona Rd, Southampton SO9 4XY, England. Para- doxical bronchoconstriction with nebulized albuterol but not with terbutaline (Case Report). Amer Rev Resp Dis 1993; 148: (2) 512

Gustafsson P, Tsanakas J, Gold M, Primhak R, Radford M, Gillies El. *Glaxo Grp Res Ltd, Dept Resp Med, Greenford Rd, Green- ford UB6 OHE, Middx, England. Comparison of the efficacy and safety of inhaled fluticasone propionate 200 mg/day with inhaled beclomethasone dipropionate 400 mg/day in mild and moderate asthma. Arch Dis Child 1993; 6 9 (2) 206

Hanzlick R. 916 Cumberland Rd NE, Atlanta, Ga 30306, USA. Na- tional Association of Medical Examiners pediatric toxicology - Re- port 2 - Phenylpropanolamine update. Amer J Foren Med Path 1993; 1 4 (3) 268

Hastier P, Bianchi D, Kuhdorf H, Arpurt JP, Chichmanian RM, Saintpaul MC, Delmont J. Hop Cimiez, Serv Hepatogastroenterol, 4 Ave Reine Victoria, BP 179, F-06003 Nice, France. Thiophene- induced hepatitis: A new case (Letter) (French, English Abstract). Gastroen CIin Biol 1993; 17: (8-9) 613

Haulman J, Robertson WO*. 118724 40th PI NE, Seattle, Wa 98155, USA. Syrup of ipecac in 1993 - A personal perspective (Guest Editorial). Drug Sofety 1993; 9 (2) 79

Leach B. 66 Keble St, Corinda, Qld 4075, Australia. Should children inhale p-agonists before exercise? (Letter). Med J Ausrralia 1993; 159 (6) 430

Lehmke J, Thimme W. Humboldt Hosp, Innere Abt I , Nordgrakn 2, D-13509 Berlin, FRG. Longterm p-agonist use and increased risk of death from asthma (Letter) (German, English Abstract). Deut Med Wochenschr 1993; 118: (27-28) 1049

Mahieu LM, Rooman RP, Goossens E. Antwerp Univ Hosp, Dept Paediat, Wilrijkst 10, B-2650 Antwerp, Belgium. Imidmline intoxication in children. Ew J Pediat 1993; 152 (1 1) 944

Seto A, Einarson T, Koren G. Hosp Sick Children, Morthe-Risk Pro- gram, Toronto, Ontario, Canada M5G 1x8. Evaluation of brom- pheniramine safely in pregnancy. Reprod Toxic01 1993; 7: (4) 393

Williams AF. St George Hosp, Sch Med, Dept Child Hlth, Cranmer Ten, London SW17 ORE, England. The effectiveness and side effects of dexamethasone in preterm infants with bronchopulmonary dysplasia (Letter). Arch Dis Child 1993; 6 9 (3 Spec issue) 331

15 NEUROMUSCULAR AGENTS

Deacock SJ. Charing Cross Hosp, London W6 8RP, England. Sore throat after suxamethonium (Letter). Brit JAnaesth 1993; 71: ( I ) 164

Dicpinigaitis PV, Nierman DM, Miller A. Mt Sinai Med Ctr, Box 1232, 1 Gustave L Levy PI, New York, NY 10029, USA. Baclo- fen-induced bronchoconstriction. Ann Phmacorher 1993; 27: (7- 8) 883

Feldman SA, Hood J. Charing Cross & Westminster, Med Sch, Lon- don, England. Pipecuronium-induced prolongation of vecuronium block (Letter). Brit JAnaesth 1993; 71: (3) 459

Melton AT, Antognini JF*, Gronert GA. *Univ Calif Davis, Dept Anesthesiol, TB-170, Davis, Ca 95616, USA. Prolonged duration of succinylcholine in patients receiving anticonvulsants: Evidence for mild upregulation of acetylcholine receptors. Can J Anaesth 1993; 4 0 (1 0) 939

Moss J. Univ Chicago, Dept Anesthesia & Crit Care, 5841 S Mary- land Ave, MC4028, Chicago, 11 60637, USA. Are histamine-releasing drugs really contraindicated in patients with a known allergy to drugs? (Letter). Anesthesiology 1993; 79: (3) 623

Rao U, Milligan KR. Belfast City Hosp, Belfast BT9 7AB, Northern Ireland. Fixed dilated pupils associated with alcuronium infkions (Letter). Anaesthesia 1993; 48: (10) 917

Saidman LJ. Address not available. Are histamine-releasing drugs really contraindicated in patients with a known allergy to drugs? (Comment). Anesfhesiology 1993; 7 9 (3) 624

Smith I, White PF. SW Med Ctr, Dallas, Tx, USA. Pipecuronium-induced prolongation of vecuronium block (Letter). Brit J Anaesth 1993; 71: (3) 460

16 REPRODUCTIVE SYSTEM AGENTS

Contraceptives and congenital anomalies (ACOG Committee Opin- ion). Int JGynecol Obstet 1993; 42: (3) 316

Estrogen replacement therapy and endometrial cancer (ACOG Com- mittee Opinion). In1 J Gynecol Obstef 1993; 4 3 (1) 89

Akerlund M, Rode A, Westergaard J. Univ Hosp Lund, Dept Obstet & Gynaecol, S-22363 Lund, Sweden. Comparative profiles of reli- ability, cycle control and side effects of 2 oral contraceptive formu- lations containing 150 pg desogestrel and either 30 or 20 pg ethinyl oestradiol. Brit J Obstet Gynaecol 1993; 100: (9) 832

Beaumont JL. Address not available. Antiethinyl estradiol antibodies (Letter). NeuroZogv 1993; 43: (9) 1860

Bell RJ, Permezel M, MacLennan A, Hughes C, Healy D, Brennecke S. Univ Melbourne, Howard Florey Inst Exptl Physiol & Med, Parkville, Vic 3052, Australia. A randomized, doubleblind, placebo-controlled trial of the safety of vaginal recombinant human relaxin for cervical ripening. Obstet Gynecol 1993; 82: (3) 328

Berenson AB, Wiemann CM. Univ Texas, Dept Obstet & Gynecol, Med Branch, Galveston, Tx 77555, USA. Patient satisfaction and side effects with levonorgestrel implant (norplant) use in adoles- cents 18 years of age or younger. Pediatrics 1993; 92: (2) 257

Bluming AZ. Univ Sthn Calif, Los Angeles, Ca 90033, USA. Hor- mone replacement and cardiovascular risk factors (Letter). N Engl J Med 1993; 329 (14) 1042

Castelo-Branco C, Deo-Saba MJM, Vanrezc JA, Fortuny A, Gon- zalez-Merlo J. Univ Barcelona, Hosp Clin & Prov, Sch Med, Dept Gynaecol & Obstet, C Villarroel 170, E-08036 Barcelona, Spain. Effects of oophorectomy and hormone replacement therapy on pituitary-gonadal function. Maruritar 1993; 17: (2) 101

Castelo-Branco C, Casals E, Sanllehy C, Gonzalez-Merlo J, Iglesias X. Univ Barcelona, Hosp Clin & Prov, Sch Med, Dept Gynaecol & Obstet, C Villarroel 170, E-08036 Barcelona, Spain. Effects of oophorectomy and hormone replacement therapy on plasma lipids, Mafuritas 1993; 17: (2) 113

CURRENT AWARENESS IN PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 55 1

Chu G, Farrell GC*. *Westmead Hosp, Dept Gastroenterol & Hepa- tol, Westmead, NSW 2145, Australia. Portal vein thrombosis associated with prolonged ingestion of oral contraceptive steroids. J Gastroenferol Hepfol 1993; 8 (4) 390

Clements D, Rhodes J. Univ Hosp Wales, Dept Gastroenterol, Heath Pk, Cardiff CF4 4XW, Wales. Hormone replacement therapy in chronic active hepatitis: A w e report. Guf 1993; 34: (1 1) 1639

Collins LC, Peiris A. Div Pulm Med, 3rd FI, ACB, 550 S Jackson, Louisville, Ky 40202, USA. Bronchospasm secondary to replacement estrogen therapy. Chest 1993; 104: (4) 1300

Crook D, Stevenson JC. Wynn Inst Metab Res, London NW8 9SQ, England. Hormone replacement and cardiovascular risk factors (Letter). NEngl JMed 1993; 329 (14) 1041

Darney P. Univ Calif San Francisco, San Francisco Gen Hosp, Dept Obstet & Gynecol & Reprod Sci, San Francisco, Ca 941 10, USA. Safety and efficiency of a triphasic oral contraceptive containing desogestrel: Results of three multicenter trials. Contracepfion 1993; 48: (4) 323

Daubresse JC. Hop Civil, B-6000 Charleroi, Belgium. Hormone replacement and cardiovascular risk factors (Letter). N Engl J Med 1993; 329 (14) 1042

Delarey N, Schall R*, Luus HG, Meyer BH, Muller FO. *Univ Or- ange Free State, Dept Pharmacol, Farmovs Inst Clin Pharmacol & Drug Dev, POB 339 G6, Bloemfontein 9300, Rep Sth Africa. As- sessing the risk of ovulation in interaction studies of drugs and oral contraceptives. In? J Clin P h r m 7'her Toxicol 1993; 31: (9) 435

De Leo V, L m t t a D, Dantona D, Danero S. Univ Siena, Dept Ob- stet & Gynecol, via P Mascagni 46, 1-53100 Siena, Italy. Growth hormone secretion of premenopausal women before and after ovariectomy - Effect of hormone replacement therapy. Ferf Sferil 1993; M): (2) 268

Delva MD. Queens Univ, Fac Med, Dept Family Med, 220 Bagot St, POB 8888, Kingston, Ontario, Canada K7N 5E9. Hormone replacement therapy: Risks, benefits, and costs. Can F m Phys 1993; 3 9 2149

Disaia PJ, Odicino F, Grosen EA, Cowan B, Pecorelli S, Wile AG, Creasman WT. Univ Calif Irvine, Dept Obstet & Gynecol, Irvine, Ca 92717, USA. Hormone replacement therapy in breast cancer (Letter). Lancet 1993; 342: (8881) 1232

Egan TM, Siegert RJ, Fairley NA. Porirua Hosp, POB 50233, Pu- rirua, New Zealand. Use of hormonal contraceptives in an institutional setting - Reasons for use, consent and safety in women with psychiatric and intellectual disabilities. N Z Med J 1993; 106: (961) 338

Famodu AA, Elom EU, Ehigiegba AE, Fakoya TA. Univ Benin, Coll Med Sci, Dept Haematol, Benin City, Nigeria. Abnormal fibrinolytic activity in African women taking oral contraceptives (Let- ter). Blood Cougulat Fibrin01 1993; 4 (4) 641

Guerrier FJ. Roger Pk Med Ctr, 500 loth Ave Sth, St Petersburg, FI 33701, USA. Patient acceptability of estrace as postmenopausal estrogen-replacement therapy. Advan Ther 1993; 1 0 (4) 167

Hemrika DJ, Slaats EH, Kennedy JC, Robles-Korsen TMD, Schoe- maker J. OL Vrouwe Gasthuis, Dept Obstet & Gynecol, LE Oos- terparkstr 279, POB 95500, 1090 Hh4 Amsterdam, The Nether- lands. Pulsatile luteinizing hormone patterns in long term oral contraceptive users. J Clin Endmrinol Metab 1993; 717: (2) 420

Jensen J. Vaerebrovej 170, DK-2880 Bagsvaerd, Denmark. Lipid and lipoprotein profiles in postmenopausal women - Effects of combined hormone replacement therapy (Summary of Doctoral The- sis). Acta Obsfet Gynecol &and 1993; 72: (6) 500

Katschinski B, Fingerle D, Scherbaum B, Goebell H. Univ Essen Ge- samthsch Klinikum, Gastroenterol Abt, Hufelandstr 55, W-4300 Essen I , FRG. Oral contraceptive use and cigarette smoking in Crohns disease. Digest Dis Sci 1993; 38: (9) 1596

Ketchum P. Address not available. Revised guidelines for oral contraceptives - Lower doses can be taken longer. Can Fam Phys 1993; 3 9 1732

Kimmerle R, Weiss R, Berger M, Kurz KH. Heinrich Heine Univ, Dept Nutr & Metab Dis, WHO Collaborating Ctr Diabet, Moorenstr 56, W-4000 Dusseldorf, FRG. Effectiveness, safety, and acceptability of a copper intrauterine device (CU Safe-300) in type I diabetic women. Diabefes Care 1993; 1 6 (9) 1227

Lanari C, Molinolo AA, Pasqualini CD*. *NaU Acad Med Buenos Aires, RA-1450 Buenos Aires, DF, Argentina. Oral contraception and breast cancer (Letter). J Nut Cancer Insf 1993; 8 5 (18) 1525

Levine SR. Address not available. Antiethinyl estradiol antibodies (Reply). Neurologv 1993; 43: (9) 1860

Lindgren A, Olsson R. Sahlgrens Univ Hosp, Med Clin, S-41345 Gothenburg, Sweden. Liver damage from low-dose oral contracep tives. J Intern Med 1993; 234 (3) 287

Manasco PK, Pescovitz OH, Blizzard RM. NIEHS, Molec & Integrat Neurosci Lab, Res Triangle Pk, NC 27709, USA. Local reactions to depot leuprolide therapy for central precocious puberty (Letter). JPediaf 1993; 123: (2) 334

Martin KA, Freeman MW. Massachusetts Gen Hosp, Boston, Ma 021 14, USA. Hormone replacement and cardiovascular risk factors (Reply). N Engl J Med 1993; 329 (1 4) 1043

Nabulsi AA, Folsom AR, White A. Burroughs Wellcome Co, Res Triangle Pk, NC 27708, USA. Hormone replacement and cardiovascular risk factors (Reply). N Engl J Med 1993; 329 (14) 1042

Neely EK, Wilson DM, Hintz RL. Stanford Univ, Med Ctr, Sch Med, Div Pediat Endocrinol, Stanford, Ca 94305, USA. Local reactions to depot leuprolide therapy for central precocious puberty (Reply). JPediaf 1993; 123: (2) 335

Palmer JR, Rosenberg L, Shapiro S. Boston Univ, Sch Med, Slone Epidemiol Unit, 1371 Beacon St, Brookline, Ma 02146, USA. Oral contraceptives and malignant melanoma (Reply). Cancer Cause Control 1993; 4 (4) 396

Pillans P, Sparrow MJ. Univ Otago, Sch Med, Natl Toxicol Grp, Dunedin, New Zealand. Pregnancy associated with a combined oral contraceptive and itraconazole (Letter). N Z Med J 1993; 106: (965) 436

Quehenberger P, Kapiotis S, Partan C, Schneider B, Wenzel R, Gaiger A, Speiser W*. Wniv Vienna, AKH Wein, Clin Inst Med & Chem Lab, Hematol Lab, Leitstelle 5J, A-1090 Vienna, Austria. Studies on oral contraceptive-induced changes in blood coagulation and fibrinolysis and the estrogen effect on endothelial cells. Ann HematoIl993; 67: (1) 33

Rafuse J. Address not available. SOGC says regulatory agencies stall- ing on approval of safe, effective contraceptives. Can Med Assn J 1993; 149 (4) 467

Russell AY, Williams MS, Farr PA, Schwab AJ, Plattsmier S. Univ Texas, Med Branch, Sch Med, Dept Pediat, Off Student Affairs, Ashbel Smith Bldg 1208, Galveston, Tx 77555, USA. Patterns of contraceptive use and pregnancy among young Hispanic women on the Texashlexico border. JAdolescenf Health 1993; 14: (5) 373

Sacks PC, Falk RJ. 2440 M St NW, Ste 401, Washington, DC 20037, USA. Hematometra associated with estrogen replacement therapy. Southern Med J 1993; 86: (7) 842

Stewart M. Address not available. Risk of cerebral thrombosis is less for lower dose oral contraceptives than for higher dosage pills. Fam Planning Perspect 1993; 25: (5) 237

Tait RC, Walker ID*, Islam SIAM, McCall F, Conkie JA, Wight M, Mitchell R, Davidson JF. *Glasgow Royal Infirm, Dept Haematol, Castle St, Glasgow G4 OSF, Scotland. Protein C activity in healthy volunteers - Influence of age, sex, smoking and oral contraceptives. Thromb Haemost 1993; 7 0 (2) 281

Thus C, Knipschild P. Univ Limburg, Dept Epidemiol, POB 616, 6200 MD Maastricht, The Netherlands. Oral contraceptives and the risk of gallbladder disease - A meta-analysis. Amer J Public Health 1993; 83: (8) 11 13

Trussell J, Stewart F, Potts M, Guest F, Ellertson C. Princeton Univ, Off Populat Res, 21 Prospect Ave, Princeton, NJ 08544, USA. Should oral contraceptives be available without prescription? Amer


J Public Health 1993; 83: (8) 1094 Tsukamoto N, Uchiyama T, Takeuchi T, Sat0 S, Naruse T, Nakazato Y. Gunma Univ, Sch Med, Dept Internal Med 3, 3-39-15 Showa cho, Maebashi, Gunma 371, Japan. Fatal outcome of a patient with severe aplastic anemia after treatment with metenolone acetate. Ann Hemutol 1993; 67: (1 ) 4 1

Weiss NS, White E. Univ Washington, Sch Pub1 Hlth & Community Med, Dept Epidemiol, Seattle, Wa 98195, USA. Oral contracep tives and malignant melanoma (Comment). Cuncer Cause Control 1993; 4: (4) 395

Wheeler JM, Knittle JD, Miller JD, Adashi E, Barnes R, Behrman J, Cameron W, Comite F, Dawood YM, Dlugi AM, et al. MPH, 6550 Fannin St, #801, Houston, Tx 77030, USA. Depot leuprolide acetate versus danml in the treatment of women with symptomatic endometriosis - A multi-center, double-blind randomized clinical trial. 11. Assessment of safety. Amer J Obstet Gynecol 1993; 169 (1) 26

Yuen J, Persson I, Bergkvist L, Hoover R, Schairer C, Adami HO. Univ Hosp Uppsala, Canc Epidemiol Unit, S-75185 Uppsala, Swe- den. Hormone replacement therapy and breast cancer mortality in Swedish women - Results after adjustment for healthy drug-user effect. Cuncer Cause Control 1993; 4: (4) 369

Zumoff B. Beth Israel Med Ctr, New York, NY 10003, USA. Hor- mone replacement and cardiovascular risk factors (Letter). N Engl JMed 1993; 329 (14) 1041

17 GASTROINTESTINAL SYSTEM AGENTS

Castellote E, Bonet J, Lauzurica R, Pastor C, Cofan F, Caralps A. Univ Hosp Germans Trias & Pujol, Dept Nephrol, Crta Canyet s-n, E-089 16 Badalona, Spain. Does interaction between omeprazole and cyclosporin exist? (Letter). Nephron 1993; 65: (3) 478

Delpre G, Lapidot A, Lipchitz A, Livni E, Kadish U. Beilinson Med Ctr, Inst Gastroenterol, IL-49100 Petah Tiqwa, Israel. Hyperpro- lactinaemia during famotidine therapy (Letter). Lancet 1993; 342: (8875) 868

Fabian TC, Croce M A Address not available. Pneumonia due to stress ulcer prophylaxis with cimetidine - A necessary consequence (Reply). Arch Surg 1993; 128 (9) 1079

Finnie IA, Gilmore IT*. *Royal Liverpool Univ Hosp, Gastroenterol Univ, Prescot St, Liverpool L7 8XP, England. Skin rash, fever and rigors caused by olsalazine. Eur J Gasnoenterol Heputol 1993; 5: (10) 881

Gaughan WJ, Sheth VR, Francos GC, Michael HJ, Burke JF. Thomas Jefferson Univ, Dept Med, Div Nephrol, 111 Sth 11th St, Ste 7320, Philadelphia, Pa 19107, USA. Ranitidine-induced acute interstitial nephritis with epithelial cell foot process fusion. Amer J Kidney Dis 1993; 22: (2) 337

Jenkins SA, Sutton R, Kingsnorth AN, Shields R. Univ Liverpool, Dept Surg, POB 147, Liverpool L69 3BX, England. Somatostatin - Safety in patients with variceal bleeding (Letter). Gastroenterology 1993; 105 (2) 642

Lesur G, Paupard T, Turner L, Bergmer AM, Parlier H, Dupuy P. Hop Ambroise Pare, Sen, Hepatogastroenterol, F-92108 Boulogne, France. Esophageal mycosis induced by omeprazole (Letter) (French, English Abstract). Gasnoen CIin Biol 1993; 17: (8-9) 598

Miller LG, Hopkinson JM, Motil KJ, Corboy JE, Andersson S. Bay- lor Coll Med, Childrens Nutr Res Ctr, Dept Family Med, Houston, Tx 77030, USA. Disposition of olsalazine and metabolites in breast milk. JClin Phurmucol 1993; 33: (8) 703

Neelakantappa K, Gallo GR, Lowenstein J. NYU Med Ctr, Dept Med, 550 1st Ave, Rm TI1 440, New York, NY 10016, USA. Ranitidine-associated interstitial nephritis and Fanconi syndrome. Amer J Kidney Dis 1993; 22: (2) 333

Popvic V, Chayvialle JA, Wass JAH*. *St Bartholomews Hosp, Dept Endocrinol, London EClA 7BE, England. Proceedings of the discussion - Tolerability and safety of sandostatin. Digestion 1993;

54: (Suppl 1) 104 Tryba M. Address not available. Pneumonia due to stress ulcer pro-

phylaxis with cimedine - A necessary consequence (Letter). Arch Surg 1993; 128 (9) 1078

18 ANTI-INFLAMMATORY AGENTS - STEROIDAL

Cohen IJ. Beilinson Med Ctr, Childrens Med Ctr, Sambur Ctr Pediat Hematol Oncol, IL-49100 Petah Tiqwa, Israel. Cardiovascular collapse after high dose methylprednisolone (Editorial). Pediut Hemo- to1 Oncol 1993; 1 0 (3) R5

Dowell SF, Bresee JS*. *Ctr Dis Control, Div Vital & Rickettsial Dis, Epidemiol Activ Sect, Mail Stop A32, Atlanta, Ga 30333, USA. Severe Vuricellu associated with steroid use. Pediufrics 1993; 92: (2) 223

Epstein A, Tratner A, David M, Sandbank M. Beilinson Med CII, Dept Dermatol, IL-49100 Petah Tiqwa, Israel. Perforation of colon diverticula during corticosteroid therapy for pemphigus vulgaris (Letter). Ann Phurmucother 1993; 27: (7-8) 979

Franchino MB. Address not available. Osteoporosis induced by corticoids (Letter) (Spanish, English Abstract). Medicinu-Buenos Aires 1993; 53: (3) 283

Hunter T. Univ Hosp British Columbia, Vancouver, Brit Columbia, Canada V6H 3N1, Acute exacerbation mimicking pseudoseptic arthritis in rheumatoid arthritis could be caused by abrupt discontinuation of glucocorticoid (Reply). JRheumutol 1993; 20: (8) 1442

Lubbe R, Neitzel L. Landeskrankenhauses Osnabruck, Neuropsychiat Abt, Osnabruck, FRG. Cortisone-induced psychosis with prolonged duration of txatment and atypical remission (German). Nerven- heilkunde 1993; 12: ( 5 ) 218

Lucas KG, H o h e DL, Phebus CK*. *Childrens Hosp Pittsburgh, Dept Pediat, Div Hematol Oncol, 1 Childrens PI, 3705 5th Ave, Desoto St, Pittsburgh, Pa 15213, USA. Cardiorespiratory decom- pensation following methylprednisolone administration. Pediut He- matol Oncol 1993; 1 0 (3) 249

Mcligeyo SO. Univ Nairobi, Coll Hlth Sci, POB 19676, Nairobi, Kenya. Muscle cramps during prednisolone treatment (Letter). Brit MedJ 1993; 307: (6907) 802

McLuckie AE, Savage RW. Natl Naval Med Res Inst, Dept Internal Med, Div Cardiol, Bethesda, Md 20814, USA. Atrial fibrillation following pulse methylprednisolone therapy in an adult. Chest 1993; 104: (2) 622

Negri AL, Spivacow FR, Zanchetta JR. Address not available. 0ste.o- brosis induced by corticoids (Letter). Medicinu-Efuenos Aires 1993; 53: (3) 284

Nekl KE, Aron DC. Case Western Reserve Univ, Sch Med, Div En- docrinol & Hypertens, Cleveland, Oh 44106, USA. Hydrocorti- sone-colestipol interaction (Letter). Ann Phurmucother 1993; 27:

Ohtake T, Kimura M*, Yoshii S, Ikegaya N, Takayanagi S, Hishida A, Kaneko E. *Univ Shizuoka, Hamamatsu Coll, 3-2-3 Nunohashi, Hamamatsu 432, Japan. Biloma during steroid therapy for minimal change nephrotic syndrome (Case Report). Internal Med 1993; 32:

Rondeau E, Kourilsky 0, Peraldi MN, Alberti C, Kanfer A, Sraer JD. Hop Tenon, Sew Nephrol A, 4 rue Chine, F-75970 Paris 20, France. Methylprednisolone and cyclophosphamide pulse therapy in crescentic glomerulonephritis - Safety and effectiveness. Renuf Fail 1993; 1 5 (4) 495

Satoh M, Ajmani AK. Univ Nth Carolina, Div Rheumatol & Immu- nol, Chapel Hill, NC 27599, USA. Acute exacerbation mimicking pseudoseptic arthritis in rheumatoid arthritis could be caused by abrupt discontinuation of glucocorticoid (Letter). J Rheumatol 1993; 2 0 (8) 1441

Singleton JD, West SG. Fitzsimons Army Med Ctr, Dept Med, Rheu-

(7-8) 980

(7) 543


matol Sew, Aurora, Co 80045. USA. Acute exacerbation mimicking pseudoseptic arthritis in rheumatoid arthritis could be caused by abrupt discontinuation of giucowrticoid (Reply). J Rheumntol 1993; 2 0 (8) 1442

Teelucksingh S, Bahall M, Coomansingh D, Ste M, Batholomew C. Port of Spain Gen Hosp, Dept Med, Port of Spain, Trinidad & Tobago. Cushing's syndrome from topical glucocorticoids. West Indian Med J 1993; 42: (2) 77

Torres V, Rui TB, Melo H, Soares AP. Desterm Hosp, Dept Derma- tol, Rua Nova Desterro, P-1100 Lisbon, Portugal. Systemic contact dermatitis from hydrocortisone. Contact Dennuti?& 1993; 2 9 (2) 106

Walsh P, Aeling JL, Huff L, Weston WL. Univ Colorado, Sch Med, Dept Dermatol, 4200 East 9th Ave, Box B153, Denver, Co 80262, USA. Hypothalamus-pituitary-adrenal axis suppression by superpo- tent topical steroids. JAmer AcadDermatol1993; 2 9 (3) 501

19 OTHERS

Older diabetics - Intensive therapy is safe and effective (News). Geri- atrics 1993; 48: (8) 21

Aneiros E, Calderon B, Mas R*, Illnait J, Castano G, Fernandez L, Femandez JC. *Natl Ctr Sci Res, Tomas Romay Policlin Ctr, POB 6880, Havana, Cuba. Effect of successive dose increases of poli- cosanol on the lipid profile and tolerability of treatment. Curr Ther Res 1993; 54: (3) 304

Averns HL, Boardman PL. Royal Shrewsbuy Hosp, Mytton Oak Rd, Shrewsbury SY3 8BR, England. Granulocyte colony-stimulating factor in drug-induced agranulocytosis (Letter). Brit J Rheumatol 1993; 32 (11) 1029

Baggish MS, Brill AI, Rosensweig B, Barbot JE, Indman PD. Good Samaritan Hosp, Dept Obstet I% Gynecol, 375 D h y t h Ave, Cin- cinnati, Oh 45220, USA. Fatal acute glycine and sorbitol toxicity during operative hysteroscopy. J Gynecol Surg 1993; 9 (3) 137

Belchi-Hernandez J, Florido-Lopez JF, Estrada-Rodriguez JL, Martinez-Alzamora F, Lopez-Semo C, Ojeda-Casas JA. C Maes- tro J Paulino Torres Blq 15, 5C, E-3ooo6 Murcia, Spain. Sulfite-induced urticaria. Ann AIZergV 1993; 71: (3) 230

Benhariz M, Goulet O*, De Potter S, Girot R, Rambaud C, Colomb V, Comol 0, Ricour C. *Hop Necker Enfants Malad, Dept Pediat Gastroenterol & Nut, Gastroenterol & Nutr Unit, F-75743 Paris 15, France. Iron overload in children receiving prolonged paren- teral nutrition. JPediur 1993; 1U: (2) 238

Binder C, Lang W. Univ Gottingen, Z e n M Innere Med, Hamatol Onkol Abt, Robert Koch Str 40, D-37070 Gottingen, FRG. Ne- crotizing hepatitis ending fatally after carbimazole treatment (Ger- man, English Abstract). Deut Med Wochenschr 1993; 118 (42) 1515

Biondi B, Fazio S, Carella C, Amato G, Cittadini A, Lupoli G, Sacca L, Bellastella A, Lombardi G*. *via G Santacoce 40-A, 1-80129 Naples, Italy. Cardiac effects of long term thyrotropin suppressive therapy with levothyroxine. J Clin Endocrinol Metab 1993; 77: (2) 334

Broadway D, Grierson I, Hitchings R. Moorfields Eye Hosp, City Rd, London EClV ZPD, England. Adverse effects of topical antiglau- comatous medications on the conjunctiva. Brit J Ophrhfmof 1993; 77: (9) 590

Calligeros D, Douglas P, Abeygunasekera S, Smith G. Prince of Wales Hosp, Div Med, Randwick, NSW 2031, Australia. Aseptic peritonitis in association with the use of pamidronate (Letter). Med J Australia 1993; 159 (2) 144

Carlson RF, Isley WL, Ogrinc FG, Klobucar TR. Upjohn Co, Kala- mamo, Mi 49001, USA. Eficacy and safety of reformulated, mi- cronized glyburide tablets in patients with non-insulindependent diabetes-mellitus: A multicenter, double-blind, randomized trial. CIin Ther 1993; 1 5 (5) 788

Chatrenet P, Regimbeau C, Ramain JP, Penot J, Bruandet P. Ctr Hosp

Gen, Sew Gastroenterol, Mail Pierre Charlot, F-41016 Blois, France. Fenofibrate-induced chronic active hepatitis with cirrhosis (Letter) (French, English Abtract). Gusfroen CIin Biol 1993; 17:

Chronos NAF, Goodall AH, Wilson AJ, Sigwart U, Buller NP. Royal Brompton Natl Heart & Lung Hosp, Dept Invas Cardiol, Sydney St, London SW3 6NP, England. Profound platelet degranulation is an important side effect of some types of contrast media used in interventional cardiology. Circulation 1993; 88: (5 Part 1) 2035

Cole PA, Bostwick JM, Fajtova VT. Brigham & Womens Hosp, Dept Med, Div Psychiat, Boston, Ma 021 15, USA. Thyrotoxicosis in a depressed patient on Ltriiodothyronine (Letter). Psychosomatics 1993; 3 4 (6) 539

Cooper RG, Kirk JWB, Bielenberg P. 4 Maryborough St, Bundaberg, Qld 4670, Australia. Mycobacterial infection associated with the use of an anabolic steroid (Letter). Med J Australia 1993; 159 (3) 215

Cunie R. Farmitalia Carlo Erba Spa, Auckland, New Zealand. Side effects ofacipimox (olbetam) Letter. N Z Med J 1993; 106: (956) 211

Dawson P, Sidhu PS. Hammersmith Hosp, Dept Diagnost Radiol, Du Cane Rd, London W12 OHS, England. Is there a role for corticosteroid prophylaxis in patients at increased risk for adverse reactions to intravascular contTaSt agents? CIin Radiol 1993; 48: (4) 225

Di Martino A. Fidia Res Labs, via Ponte Fabbrica 3A, 1-35031 Abano Terne, Italy. Transmissible spongiform encephalopathies and the safety of naturally-derived biologicals. Biofogicds 1993; 21: (1) 61

Dorozynski A. Address not available. French to investigate deaths from growth hormone (News). Brit Med J 1993; 307: (6899) 281

Duffull SB, Gaudin JR. Christchurch Hosp, Dept Clin Pharmacol, Christchurch, New Zealand. The relevance of gluten in pharmaceu- tical products (Letter). N Z Med J 1993; 106: (961) 344

G l o h r DE. Boston Univ, Boston City Hosp, Sch Med, Dept Pediat, Boston, Ma 021 18, USA. The current role of 2,3-dirnercaptosuc- cunic acid (DMSA) in the management of childhood lead poisoning (Commentary). Drug Wety 1993; 9 (2) 85

Grant DJ, McMurdo MET, Mole PA, Paterson CR, Davies RR. Univ Dundee, Ninewells Hosp & Med Sch, Dept Med, Ageing & Hlth Sect, Dundee DDl 9SY, Scotland. Suppressed TSH levels secondary to thyroxine replacement therapy are not associated with osteoporosis. CIin EndocrinoI 1993; 39 (5 ) 529

Grunberger G. Wayne State Univ, Ctr Hlth 4H, 4201 St Antoine, De- troit, Mi 48201, USA. Continuous versus intermittent sulphony- lwea therapy in non-insulin-dependent diabetes mellitus (Commen- tary). Drug Safety 1993; 9 (4) 249

Ham T, Sat0 T, Takeichi M. Saga Med Sch, Dept Psychiat, 5-1-1 Nabeshima, Saga 849, Japan. Iodine-induced delirium. Hum Pv- chopharmacol CIin Exp 1993; 8 (1) 59

Hernandez BEM, Persaud JW, Varghese Z, Moorhead JF*. *Royal Free Hosp, Dept Nephrol, Pond St, London NW3 ZQG, England. Low-dose simvastatin is safe in hyperlipidaemic renal transplant patients. Nephrol Dialysis Transplant 1993; 8: (7) 637

Hjalmas K, Bengtsson B. Ostra Hosp, S-41685 Gothenburg, Sweden. Efficacy, safety, and dosing of desmopressin for nocturnal enuresis in Europe. CIin Pediur 1993; (Spec Iss) 19

Ishii M, Miyazaki Y, Yamamoto T, Miura M, Ueno Y, Takahashi T, Toyota T. Tohoku Univ, Sch Med, Dept Internal Med 3, Sendai, Miyagi 980, Japan. A case of drug-induced ductopenia resulting in fatal biliary cirrhosis. Liver 1992; 13: (4) 227

Ismail HM, Al-Idrisi HY, Al-Kalaf J. King Fahd Hosp Univ, Dept Neurol, CMMS 47, POB 2114, Dammam 31451, Saudi Arabia. Combined myo-neuro-toxicity by bemfibrate (Letter). Saudi Med J 1993; 1 4 (1) 86

Jeanmougin M, Manciet JR, De Prost Y, Reygagne P, Pinquier L, Dubertret L. Hop St Louis, Unite Photodematol, 1 Ave Claude Vellefaux, F-75010 Paris, France. Photoallergy induced by fenofibrate. Ann Dermatof Venereol1993; 120 (8) 549

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Kondo N, Yamada Y, Asano J, Yagi Y, Orii T. Gifu Univ, Sch Med, Dept Pediat, Gifu 500, Japan. Malignant lymphoma in a Bloom's syndrome patient treated with insulin. Clin Gener 1993; 44: ( I ) 51

Kontoghiorghes GJ. Univ London, Royal Free Hosp, Sch Med, Dept Haematol, London NW3 2QG, England. Misinformation about de- feriprone (LI) (Letter). Lancer 1993; 342: (8865) 250

Kung AWC, Lorentz T, Tam SCF. Univ Hong Kong, Queen Mary Hosp, Dept Med, Pokfulham Rd, Hong Kong, Hong Kong. Thy- roxine-suppressive therapy decreases bone mineral density in postmenopausal women. Clin Endocrinol 1993; 39 ( 5 ) 535

Lang CJG, Rabas-Kolominsky P, Engelhardt A, Kobras G, Konig HJ. Univ Erlangen Nurnberg, Dept Neurol, Schwabachanlage 6, W- 8520 Erlangen, FRG. Fatal deterioration of Wilson's disease after institution of oral zinc therapy (Letter). Arch Neurol 1993; 50: (10) 1008

Lemp M A Univ Ophthalm Consultants Washington, 4910 Massachu- setts Ave NW, Ste 210, Washington, DC 20016, USA. Tear film, pharmacology of eye drops, and toxicity. Curr Opin Ophthalmol 1993; 4 (4) 14

Leung R, Puy R, Czamy D. St Vincents Hosp, Dept Resp Med, Fitzroy, Vic 3065, Australia. Thiamine anaphylaxis (Letter). Med J Australia 1993; 159 (5) 355

Maduh EU, Porter DW, Baskin SI*. *US Army Med Res Inst Chem Def, SGRD UV PB, Div Pharmacol, Bldg E-3100, Aberdeen Prov- ing Ground, Md 21010, USA. Calcium antagonists: A role in the management of cyanide poisoning. Drug Safe@ 1993; 9 (4) 237

McGuinness ME, Talbert RL Univ Texas Hlth Sci Ctr, Dept Pharma- col, Clin Pharm Program, 7703 Floyd Curl Dr, San Antonio, Tx 78284, USA. Phenformin-induced lactic acidosis: A forgotten adverse drug reaction. Ann fharmacother 1993; 27: (10) 1183

Mills CM, Knight AG. Univ Hosp Wales, Dept Dermatol, Heath Pk, Cardiff CF4 4XW, Wales. Cutaneous calcinosis - An unusual complication of intravenous phosphate administration. Clin Exp Der- mato/ 1993; 18 (4) 370

Moore DF, Wood DF, Volans GN*. *Guys Hosp, Natl Poisons Unit, London SEI 9RT, England. Features, prevention and management of acute overdose due to antidiabetic drugs. Drug Safety 1993; 9 (3) 218

Muniva M, Kavitsky D, Schainker BA, Poyser A, Peek C, Nance S+. *Amer Red Cross Blood Sew, Penn Jersey Reg, Tech Sew, 23rd & Chestnut Ave, Philadelphia, Pa 19103, USA. Hemolytic anemia associated with injection of fluorescein (Case Report). Tramfiion 1993; 33: (8) 689

Pajus I, Lestang P, Liote F, Dryll A. Hop Lariboisiere, F-75475 Paris 10, France. Erythroderma after clodronate treatment. Brit Med J 1993; 307: (6902) 484

Pemberton M, Yeoman CM, Clark A, Craig GT, Franklin CD, Gawk- rodger DJ. Shefield Sch Clin Dent, Dent Oral & Maxillofacial Surg, Claremont Crescent, Shefield S10 2TA, England. Allergy to octyl gallate causing stomatitis. Brit Dent J 1993; 175 (3) 106

Porter GA. Oregon Hlth Sci Univ, Dept Med, Portland, Or 97201, USA. Contrast medium associated nephropathy: Recognition and management. Invest Radio/ 1993; 2 8 (Suppl 4) SI 1

Pospelova TI, Ageeva TA, Loseva MI, Shkuruply VA, Grek OR, Pupyshev AB. Novosibirsk Med Inst, Novosibirsk, Russia. Ad- verse effects of fermm lec (Russian, English Abstract). Gematol Tramfiiol 1992; 37: (9-10) 25

Powe NR, Moore RD, Steinberg EP. Johns Hopkins Med Inst, Welch Ctr Prevent Epidemiol & Clin Res, 600 Nth Wolfe St, Carnegie 284, Baltimore, Md 21287, USA. Adverse reactions to contrast media: Factors that determine the cost of treatment. Amer J Roentgen01 1993; 161: ( 5 ) 1089

Ramsey BW, Astley SJ, Aitken ML, Burke W, Colin AA, Dorkin HL, Eisenberg JD, Gibson RL, Hanvood IR, Schidlow DV er a/ . Childrens Hosp & Med Ctr, Ctr Cyst Fibrosis, 4800 Sand Point Way NE, POB C-5371, Seattle, Wa 98105, USA. Efficacy and safety of short-term administration of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis. Amer Rev

Resp Dis 1993; 148: (1) 145 Santeusanio F, Ventura MM, Contadini S, Compagnucci P, Moriconi

V, Zaccarini P, Marra G, Amigioni S, Biachi W, Brunetti P. Univ Perugia, 1st Med Interna & Sci Endocrine & Metab, via E Dal Pozzo, 1-06126 Perugia, Italy. Efficacy and safety of 2 different dosages of acarbose in non-insulin dependent diabetic patients treated by diet alone. Diabetes Nufr Metab 1993; 6 (3) 147

Schurholz T, Schulze H. Ruhr Univ Bochum, Marienhosp 2, Urol Klin, Widumer Str 8, W-4690 Heme 1, FRG. Iodine-induced hyperthyroidism caused by contrast media in urology - Risks and prevention. Urologe-Aurg A 1993; 32: (4) 300

Schut NH, Wiersinga WM, Van Oers MH. Kennemer Gasthuis, Boer- haavelaan 22, 2035 RC Haarlem, The Netherlands. Methimamle- induced agranulocytosis preceded by transient granulocytopenia - A case report. Neth J Med 1993; 4 3 (1 -2) 7 1

Schwartz ML. Thomas Jefferson Univ, Ste G-4280, Philadelphia, Pa 19107, USA. Severe reversible hyperglycemia as a consequence of niacin therapy. Arch Intern Med 1993; 153: (17) 2050

Segers 0, Musch W, Schoors DF. Vrije Univ Brussels, AZ, Dept Internal Med, Laarbeeklaan 101, B-1090 Brussels, Belgium. Early complications of radioiodine treatment for hyperthyroidism. Acta Clin Berg 1993; 4 8 (4) 253

Shellock FG, Hahn HP, Mink JH, Itskovich E. Tower Imaging, 444 Sth San Vincente Blvd, St 106, Los Angeles, Ca 90048, USA. Ad- verse reaction to intravenous gadoteridol. Radiology 1993; 189 ( I ) 151

Silcox J, Schulz P, Horbay GLA, Wassenaar W*. *Ferring Inc, Dept Clin Res, 515 Consumers Rd, Ste 304, Toronto, Ontario, Canada M2J 422. Transfer of carbetocin into human breast milk. Obsret Gynecoll993; 82: (3) 456

Tabar AI, Garcia BE, Rodriguez A, Quirce S, Olaguibel JM. Virgen Camino Hosp, Allergol Sect, Plaza Paz S-N, E-31004 Pamploma, Spain. Etiologic agents in allergic contact dermatitis caused by eyedrops. Contact Dermatitis 1993; 2 9 (1) 50

Walton RG, Hudak R, Greenwaite RJ. Western Reserve Care Syst, Dept Psychiat, 500 Gypsy Lane, Youngstown, Oh 44501, USA. Adverse reactions to aspartame - Double blind challenge in patients from a vulnerable population. Biol Pgchiar 1993; 3 4 (1-2) 13

Wiholm BE, Myrhed M. Med Prod Agcy, Div Drug Epidemiol Infor- mat & Inspect, POB 26, S-75103, Uppsala, Sweden. Metformin-associated lactic acidosis in Sweden 1977-1991. Eur JClin Pharma- col1993; 4 4 (6) 589

Wilkerson M, Cyrlin M, Lippa EA*, Esposito D, Deasy D, Panebi- anco D, Fazio R, Yablonski M, Shields MB. 'Merck Sharp & Do- hme Ltd, West Point, Pa 19486, USA. Four week safety and eficacy study of donolamide, a novel, active topical carbonic anhy- drase inhibitor. Arch Ophthalmol 1993; 111: (10) 1343

Wuster C, Schoter KH, Thiebaud D, Manegold C, Krahl D, Clemens MR, Ghielmini M, Jaeger P, Scharla SH. Univ Heidelberg, Dept Internal Med I, Bergheimerstr 58, D-69115 Heidelberg, FRG, Methylpentylaminopropylidenebisphosphonate (BM-21.0955) - A new potent and safe bisphosphonate for the treatment of cancer-associated hypercalcemia. Bone Miner 1993; 22: (2) 77

Yarasheski KE, Zachwieja JJ. Washington Univ, Sch Med, St Louis, Mo 63 110, USA. Growth hormone therapy for the elderly - The fountain of youth proves toxic (Letter). J Am Med Assn 1993; 2 7 0 (14) 1694

Zala G, Schmid M, Buhler H. Stadtspital Waid, Med Klin, Tiechester 99, CH-8037 Zurich, Switzerland. Fulminant hepatitis caused by disulfiram (German, English Abstract). Deut Med Wochemchr 1993; 118: (38) 1355

Zierz S, Schroder R, Unkrig CJ. Univ Bonn, Neurol Klin, Sigmund Freud Str 25, D-53105 Bonn, FRG. Thrombocytopenia induced by erucic acid therapy in patients with X-linked adrenoleukodystro- phy. Clin Investigator 1993; 71: (10) 802

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