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Pertussis evolving epidemiology and strategies for preventionDr Dave GrahamCommunity and General PaediatricianWaikatoBIO/GEN/0012b/11

1Declaration of conflict of interestGlaxoSmithKline invited speaker Conference attendance supported by GSKAdditional conflicts/comments Not an infectious disease specialist Clinical and research interests in population immunisation strategies, general and developmental paediatrics, and optimised acute care practice2Pertussis is backTake home messagesIts a bad bugIts most common and most severe in babiesStandard vaccination protocols are insufficientWe need some innovative strategiesRead the book

How serious is the burden of disease?Pertussis New Zealand: notifications rising in 2011-12Institute for Environmental Surveillance and Research. Pertussis Report. March 2012. Weeks 8-9: 18 Feb 2 Mar 2012. Wellington: ESR; 2012. http://www.surv.esr.cri.nz/surveillance/PertussisRpt.php

Pertussis epidemics typically peak in 3-4 year cycles5Pertussis cases and rates 2012Institute for Environmental Surveillance and Research. Pertussis Report. March 2012. Weeks 10-11: 3 16 Mar 2012. Wellington: ESR; 2012. http://www.surv.esr.cri.nz/surveillance/PertussisRpt.php

NZ: most reported cases are in babies

Institute for Environmental Surveillance and Research. Pertussis Report. November 2011. Weeks 48, 49: 26 Nov - 09 Dec 2011. Wellington: ESR; 2011. http://www.surv.esr.cri.nz/surveillance/PertussisRpt.php Pertussis affects all ages, but highest incidence in infants.

Institute for Environmental Surveillance and Research. Pertussis Report. November 2011. Weeks 48, 49: 26 Nov - 09 Dec 2011. Wellington: ESR; 2011. http://www.surv.esr.cri.nz/surveillance/PertussisRpt.php

7Australia: children admitted to hospital with pertussis, 2009201044% of children hospitalised for pertussis were aged