pawson legacy

11
Tony Pawson His Legacy Jane McGlade, Tony Pawson & Mike Moran

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Slides presented at the tribute to Dr. Tony Pawson on August 26th, 2013.

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Page 1: Pawson legacy

Tony PawsonHis Legacy

Jane McGlade, Tony Pawson & Mike Moran

Page 2: Pawson legacy

Awards

NCIC Senior Scientist

Terry Fox Cancer Research Scientist

Kyoto Prize

Gairdner awardOrder of Ontario

Order of CanadaFRS

Order of Companions of HonourFRSC

Robert Noble Prize

Apotex Chair

HHMI International Scholar

John Colter award

Henry Friesen Award

AACR Pezcoller award

Boehringer Mannheim PrizeWolf Prize

H.P. Heineken Prize

Flavelle Medal

CIHR Distinguished Scientist

University Professor

J. Allyn Taylor Prize

Killam Prize

Prix Galien

Premiers Platinum Medal

Premiers Summit awardMichael Smith Prize

EMBO Member Poulsson Medal

National Academy of Sciences

AAASErnst Bertner

Memorial award

Canadian Medical Hall of Fame

Daniel Nathans award

Royal Medal

Louisa Gross Horwitz Prize

Honorary MemberJapan Biochemical Society Howard Taylor Rickets award

NCIC Diamond Jubilee award

Doctor of MedicineKarolinska Institutet

Honorary degreeMcMaster University

CCRA award CNPN Distinguished Researcher Award

Page 3: Pawson legacy

TraineesGeraldine Weinmaster, Jane Ingman-Baker, Michael Brose, Alister McCauley, Ivan Sadowski, Jim Stone, Peter Greer, Gareth Taylor, Kelly Meckling-Gill, Angela Brooks-Wilson, Mike Moran, Anne Koch, Vladimir Lhotak, Michael Reedijk, Ken Letwin, Deborah Anderson, Christine Ellis, Jane McGlade, Johne Liu, Luc Marengere, Lee Mizzen, Gen-Sheng Feng, Lori Puil, Mark Henkemeyer, Paul Oliver, Alex Singer, Louise Larose, Maria Rozakis-Adcock, John O'Bryan, Alec Cheng, Abhijit Guha, Norma Masson, Michael Rosen, Motti Anafi, Peter van der Geer, Ritu Dhand, Sacha Holland, Yuh-Min Chook, Wolfgang Vogel, Venus Lai, Tracy Saxton, Laura Velazquez, Nadia Al-Alawi, Shun-Cheng Li, Terrance Kubiseski, Ryuchi Sakai, Friedemann Kiefer, Xiangmin Wang, Elke Aippersbach, Dan Lin, Friedhelm Bladt, Berivan Baskin, David Stapleton, Kathleen Binns, David Murray, Robin Taylor, Nicola Broughton, Robert Steven, Karen Colwill, Neil Warner, Jiefei Tong, Perry Howard, Piers Nash, James Fawcett, William Hardy, Sabine Elowe, Leanne Groot, Robert Ingham, Gerry Gish, Siew-Hwa Ong, Sigal Gelkop, Pamela Plant, Ivan Blasutig, Matthew Smith, Nina Jones, Clark Wells, Amy Holdorf, Bruce Seet, Linda Salomonsson, Jin Jing, Rizaldy Scott, Giselle Wiggin, James Murphy, Caesar Lim, Andreas Traweger, Jacky Chung, Rune Linding, Jin Gyoon Park, Chen Chen, Yong Zheng, Claus Jorgensen, Kelly Pike, Jason Cohn, Andrew Sherman, Mark Engelhardt, Rachel Vanderlaan, Elizabeth Gray, Chris Tan, Oliver Rocks, Nicolas Bisson, Heike Wegmeyer, Sebastian Guettler, Nisa Dar, Mark van Eekelen, Rick Bradshaw, Yanling Zhao, Evangelia Petsalakis, Mohammed Soliman, Bernard Liu, Andreas Helbig, Kristina Lorenzen, James Knight, Melissa Stacey, Ruijin Tian, Timothy Nott, Melany Wagner, Greg Findlay, Igal Louria-Hayon, Michael Kofler, Frederic Fellouse, Eden Fussner

Current StaffGeraldine Mbamalu, Karen Colwill, Julie Ruston, Sarang Kulkarni, Marina Olhovsky, Monika Tucholska, Cunjie Zhang, Adrian Pasculescu, Lorne Taylor, Rizaldy Scott, Cristina Virag, Marilyn Hsiung, Jianmei Du, Zofia Krzyzek

Page 4: Pawson legacy

Collaborations

The SH2 domain (bound to a target peptide)- prototype of regulatable protein-protein interactions

The Little Domain that Could

Page 5: Pawson legacy

Protein Domains

Science. 2009 Nov 27;326(5957):1220-4.

Page 6: Pawson legacy

Another Form of Interaction

Tony trained and collaborated with many scientists throughout his career. The next four slides, created by Dr. Gary Bader, diagram those interactions, starting at the highest magnification (number of co-authored papers) and panning out.

Page 7: Pawson legacy

Co-authored 15 papers or more Courtesy of Gary Bader

Page 8: Pawson legacy

Courtesy of Gary BaderCo-authored 10 papers or more

Page 9: Pawson legacy

Courtesy of Gary BaderCo-authored 5 papers or more

Page 10: Pawson legacy

1546 coauthors422 papers

All papersCourtesy of Gary Bader

Tony’s interactome

Page 11: Pawson legacy

Thinking about how things work“None of the progress that I have made has been achieved solely as an individual. As I have mentioned, I was trained by brilliant and inspiring mentors, and I have had the benefit of a collegial group of scientists around the world, who have made the field of cell signaling exceptionally enjoyable and productive. I could have done nothing without the dedication, insights and hard work of outstanding students and postdoctoral fellows, many of whom are now highly successful independent scientists in their own right.” Kyoto Prize speech

Jeremy, Catherine & Nick

Pawsoncirca 2005