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    1

    Terms in Oncology & Its Causes

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    2

    Objectives

    After studying this chapter, you will be able to: Name the types of cancer, discuss the major

    pathological conditions, and list some of the

    possible causes

     Define the combining forms used in building

    words that relate to oncology

     

    Identify the meaning of related abbreviations

     Name the laboratory tests and clinical

    procedures used in testing and treating cancer 

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    3

    Objectives Part 2 

    Describe the pathological terms related tocancer 

     Define surgical terms related to cancer 

     List common pharmacological agents used in

    treating cancer 

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    4

     Neoplasms

    ncology is the study, diagnosis, and treatment

    of tumors !neoplasms"#

    Neoplasms

     

    $rowths made up of cells that reproduce abnormally %umor cells lac& the mechanism to stop producing and they

    lac& the ability to die after a certain period

     Apoptosis is the death of normal cells in a normal time cycle

     %umors can be either benign or malignant

    'enign (alignant

     encapsulated

     not life)threatening

     

    made up of

    differentiated cells

     not capsulated

     categori*ed by the types

    of tissue from which they

    develop

     

    can be life)threatening

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    Carcinoma!arcoma+arcinoma riginates from epithelial 

    tissue and is the most

    common type of cancer 

     

    Also called solid tumors

     +ommon sites for

    carcinomas:

      )s&in

    )lungs)breasts

      )colon

    arcoma

     riginates in muscle or

    connective tissue and

    lymph

     

    A fairly rare form of cancer 

     +ertain leu&emias are

    sarcomas) stomach

    ) mouth

    ) uterus

     pread by way of the

    lymphatic system

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    "

    #i$e% Tissue Tumor (i-ed)%issue %umor  Derives from tissue that is capable of

    separating into either epithelial or connective

    tissue because it is composed of several types

    of cells

     +an be teratomas, which are growths

    containing bone, muscle, s&in, glandular tissue

    and other cells

    N%.: A class of cancer such as

    leu&emia arises from blood, lymph or

    nervous system cells

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    '

    Causes o( Cancer +auses of +ancer  Inherited defect transmitted

    to the child in DNA

    .-posure to carcinogens

    %ypes of +arcinogens

     .nvironmental agents

     +hemicals

     

    /adiation

     

    0iruses

    ther +ancer

    +ausing Agents

     

    tobacco 

    smo&e

     asbestos

     insecticides

     

    certain dyes

     certain hormones

    DNA

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    )

    Combining *orms &

    +bbreviations ,blast-+ombining 1orm (eaning

     blast!o"

     carcin!o"

     muta

     mutagen!o"

     onc!o"

     radi!o"

    immature cell

    cancer 

    genetic change

    genetic change

    tumor 

    radiation, 2)rays

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    1.

    Combining *orms &

    +bbreviations ,/blast-

    uffi- (eaning

    )blast

    )oma

    )plasia

    )plasm

    )plastic

    immature cell

    tumor 

    formation !as of cells"

    formation !as of cells"

    formative

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    11

    Combining *orms &

    +bbreviations ,+00-Abbreviation (eaning

    ALL

    A(L

    b-

    +A

    +.A

    chemo

    +LL

    acute lymphocytic leu&emia

    acute myelogenous leu&emia

    biopsy

    carcinoma

    carcinogenic embryonic antigen

    chemotherapy

    chronic lymphocytic leu&emia

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    12

    Combining *orms &

    +bbreviations ,C#0-Abbreviation (eaning

    +(L

    D.

    DNA

    D/.

    ./

    (.%

    N3L

    chronic myelogenous leu&emia

    diethylstilbestrol

    deo-yribonucleic acid

    digital rectal e-am

    estrogen repair 

    metastases

    non)3odg&in4s lymphoma

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    13

    Combining *orms &

    +bbreviations ,P!+-Abbreviation (eaning

    5A

    rad

    /NA

    /%

    %N(

    %-

    2/%

    prostate)specific antigen

    radiation absorbed dose

    ribonucleic acid

    radiation therapy

    tumor, nodes, metastasis

    treatment

    -)ray or radiation therapy

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    outine #e%ical $amination/outine (edical .-amination

     

    5ap smear 

      ) test for cervical and

    uterine cancer 

     

    'reast e-am

      ) palpate for lumps in the

    breast

     Digital rectal e-am

      )screening for prostate

    cancer 

     

    %esticular e-am

      ) palpate for tumors in

    testes

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    loo% Tests'lood %ests

     +arcinoembryonic antigens

    !+.A"

    ) detects gastrointestinal

    tumors

     

    5rostate)specific antigen

    !5A"

      ) detects prostate cancer 

     Alphafetoprotein test !A15"

      ) detects liver or testicular

    cancer 

     3uman chorionic

    gonadotropin !3+$"

      ) present with testicular

    cancer 

     +ancer antigen 678 !+A)

    678"

      ) protein produced by

    ovarian cancer cells

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    1"

    Categoriing Tumors

    %umors are categori*ed by:

    +ategori*ing %umors

     grade !the maturity of the tumor"

     stage !the degree the tumor has spread"

     appearance !using a microscope and by

    visual observations"

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    1

    #icroscopic $amination(icroscopic .-amination

    Determines if a tumor is:

     

    alveolar   ) forming small sacs shaped

    li&e alveoli

     anaplastic

      ) reverting to a more

    immature form

     carcinoma in situ

      ) contained at a site

    without spreading

     diffuse

      ) spreading evenly

     dysplastic

      ) abnormal in cell

    appearance

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    1'

    #icroscopic $amination Part 2(icroscopic

    .-amination !cont4d"

     epidermoid

      ) resemblingepithelial cells

     

    follicular 

      ) containing

    glandli&e sacs

     

    hyperchromatic

      ) intensely colored

     hyperplastic

      ) e-cessive

    development of cells

     

    pleomorphic

      ) having many types of

    cells

     undifferentiated  ) lac&ing a defined cell

    structure

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    1)

    isual $amination0isual .-amination

     cystic

      ) filled with fluid

     fungating

      )projecting in a

    mushroom)li&e pattern

     

    medullary

      ) large and fleshy

     necrotic

      ) containing dead tissue

     polypoid

      ) containing polyps

     

    verrucous

      ) having wart)li&e,

    irregular growths

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    2.

    a%iation T6erapynce a tumor is confirmed as malignant, doctor

    and patient discuss and agree on a course of

    treatment !protocol"#

    /adiation %herapy radiation rays damage the DNA of tumor cells

     surrounding normal cells usually suffer

    damage during treatments with radiation

    ide .ffects

     hair loss

     

    nausea

     s&in damage

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    Pat6ological Terms%ype of +ancer  9here +ancer tarts

    adenocarcinoma

    astrocytoma

    basal cell carcinoma

    'ur&itt4s lymphoma

    carcinoma

    carcinoma in situ

    chondrosarcoma

    .wing4s sarcoma

    gland

    neuroglia

    s&in

    lymph

    epithelial tissue

    encapsulated tumor 

    cartilage

    connective tissue

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    Pat6ological Terms Part 2%ype of +ancer  9here +ancer tarts

    fibrosarcoma

    glioblastoma

    3odg&in4s disease

    hypernephroma

    aposi4s sarcoma

    leiomyosarcoma

    leu&emia

    leu&opla&ia

    connective tissue

    neurological tissue

    lymph system

    &idneys

    s&in and organs of AID

    patients

    smooth muscle

    stem cells

    tongue or chee&s

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    Pat6ological Terms Part 3%ype of +ancer 9here +ancer tarts

    liposarcoma

    lymphoma

    medulloblastoma

    melanoma

    multiple myeloma

    nephrosarcoma

    fat

    lymph system

    brain

    s&in

    bone marrow and bone

    &idney

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    Pat6ological Terms Part 4%ype of +ancer 9here +ancer tarts

    neuroblastoma

    non)3op&in4s

    lymphoma

    osteosarcoma

    retinoblastoma

    rhabdomyosarcoma

    sarcoma

    adrenal glands

    lymph tissue

    bone

    retina

    striated muscle

    connective tissue

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    !urgical Terms

    urgical

    5rocedures

    Incisional biopsy

     /emoval of part

    of a tumor for

    e-amination

    .-cisional biopsy

     /emoval of the

    tumor and

    surrounding

    tissue

    /esectioning

     /emoval of the

    tumor and a

    large amount of

    the surrounding

    tissue

    .-enteration

     /emoval of an

    organ, tumor, and

    surrounding tissue

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    2"

    Ot6er !urgical Proce%uresther urgical 5rocedures

     +ryosurgery

      ) destruction by

    free*ing

     .lectrocauteri*ation

      ) destruction by

    burning

     1ulguration

      ) destruction by high)

    fre;uency current

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    2

    P6armacological Terms+hemotherapy 

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    2'

    +pply 7our 8no9le%ge3arry has just returned from his follow)upappointment with his physician# 3e has been

    informed by his physician that the tumor is

    harmless# 9hich of the following terms would

    best describe this tumor=

    A# benign

    '# sarcoma

    +# malignant

    Answer: A# benign

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    2)

    +pply 7our 8no9le%ge Part 2Dr# >ennings, the oncologist, informs his patientthat tumor metastasis has occurred# ?ou reali*e

    this means:

    A# %he tumor has stopped growing in si*e#

    '# %he tumor has spread#

    +# %he tumor has disappeared#

    Answer: '# %he tumor has spread#

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    3.

    +pply 7our 8no9le%ge Part 3>ohn has a strong family history of testicularcancer# 9hich of the following blood tests might

    his oncologist order to test for testicular cancer=

    A# 5A and +A)678

    '# A15 and 3+$

    +# 5A and A15

    Answer: ' A15 and 3+$