path to my career goal - for nsf career proposal writing workshop xingwei (vivian) wang, ph.d....
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![Page 1: Path to My CAREER Goal - for NSF CAREER Proposal Writing Workshop Xingwei (Vivian) Wang, Ph.D. Assistant Professor Department of Electrical and Computer](https://reader036.vdocuments.mx/reader036/viewer/2022062715/56649d955503460f94a7e13a/html5/thumbnails/1.jpg)
Path to My CAREER Goal- for NSF CAREER Proposal Writing Workshop
Path to My CAREER Goal- for NSF CAREER Proposal Writing Workshop
Xingwei (Vivian) Wang, Ph.D.
Assistant ProfessorDepartment of Electrical and Computer Engineering
University of Massachusetts Lowell
Phone: (978) [email protected]
http://faculty.uml.edu/xwang
Xingwei (Vivian) Wang, Ph.D.
Assistant ProfessorDepartment of Electrical and Computer Engineering
University of Massachusetts Lowell
Phone: (978) [email protected]
http://faculty.uml.edu/xwang
![Page 2: Path to My CAREER Goal - for NSF CAREER Proposal Writing Workshop Xingwei (Vivian) Wang, Ph.D. Assistant Professor Department of Electrical and Computer](https://reader036.vdocuments.mx/reader036/viewer/2022062715/56649d955503460f94a7e13a/html5/thumbnails/2.jpg)
NSF CAREER Proposal
• What is an NSF CAREER proposal?• Is it the same as the regular NSF
proposals?
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NSF CAREER Proposal
• A roadmap
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NSF CAREER Proposal
• A roadmap• Where am I now?• Where do I want to
go?• Which path to take?
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NSF CAREER Proposal
• A roadmap• Who am I and where
am I now?• What is my long-
term CAREER goal?• How to reach my
goal?
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My Long Term CARER Goal
• Become a leader in the optical sensing area.
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7
Who Am I?
• Education– M.S., Ph.D., Electrical and Computer
Engineering Virginia Tech.– Certificate, Future Professoriate, Virginia
Tech.– B.S., Electrical and Computer Engineering,
Zhongshan University, Guangzhou, China.
• Training– Combination of expertise in electrical
engineering, optics, and sensor technology.
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Research Activities in VT• Biosensors
– “an oligonucleotide functionalized fiber probe with a miniature protrusion for label-free DNA sequence detection”
– won Paul E. Torgerson Research Excellence Award (2006) from Virginia Tech (VT).
• Sensors for harsh environment applications– successfully verified near the fan of a turbine engine
– 6 VT invention disclosures; 1 licensed to a company (Prime Photonics) for commercialization.
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Research Activities in UML• Biosensors
– Massachusetts Life Science Center (MLSC) New Investigator Research Award
• Optical fiber tip blood pressure sensor – Sponsored by UMass Commercial Ventures and Intellectual Property
(CVIP) – 1 provisional patent
• Optical temperature sensor – an NSF collaborative grant
• Miniature optical acoustic sensors using MEMS technology – Sponsored by Army Research Lab (ARL)– 1 US patent
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Blood Pressure Sensor• Initial market thrust: angioplasty $8 billion/year.
• Broad applications: pressure measurements in lung, brain, intestines and other areas.
• PCT International Application for filling in the US receiving office, Application No. PCT/US10/40460 (29 June 2010)
UML SensorPressureWire® (St.
Jude Medical)**
Optical Electrical
Immune to EMI Susceptible to EMI
Biocompatible materialElectrical wires inside
the patient body
~ $50 ~ $600
Comparison with current pressure sensor
** http://www.radi.se/home.aspx?n=8&m=6&s=8&r=1
Guide wire
355.6µm (ID)
Sensor Head
125µm (OD)
Photo of the a blood pressure sensor inserted in a guidewire.
The pressure sensor in the left anterior descending coronary artery
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Blood Pressure SensorFractional flow reserve (FFR)
Plaque: Pa/Pd = 0.7
No plaque: Pa/Pd = 11700 1720 1740 1760 1780
44
46
48
50
52
54
Pre
ssur
e (m
mH
g)
Time (s)
Pressure Pressure Mean Value Pressure
decreased from 50 mmHg to 45 mmHg, caused by complete occlusion of coronary vessel
Blast event measurement (Fast response)
18.848 18.850 18.852 18.854 18.856 18.8580.440
0.445
0.450
0.455
0.460
Out
put (
V)
Time (ms)
Optical fiber sensorSampling rate: 2.5 MHz
18.580 18.584 18.588 18.592 18.596 18.6000.00
0.01
0.02
0.03
0.04
0.05
0.06
O
utpu
t (V
)
Time (ms)
Reference sensorSampling rate: 2.5 MHz
Blast wave response comparison. The rise time of our sensor is 0.4 μs. The reference sensor is 12 μs.
Rise time of our sensor is 0.4 μs Rise time of the reference sensor is 12 μs
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Relationship between CAREER goal and prior funding support?
Long-term goal: leader in optical sensing
Temperature sensor (NSF)
Biosensor (MLSC)Blood
pressure sensor (CVIP)
CAREER: Ultrasound generator & receiver
Pressure sensor (ARL)
CAREER topic?
CAREER topic?
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CAREER Proposal Topic
Coronary intravascular ultrasound (IVUS) for coronary artery disease diagnosis
Application and Marketing
Optical Electrical
Miniature Size? 125 µm diameter Millimeter size
Safety to patients for in-vivo applications?
Yes. Biocompatible material.
Depends on packaging. Electrical wires inside the patient body.
Work in strong electromagnetic environments?
Yes. Immune to EMI.
No. Susceptible to EMI
High Temperature Survivability?
Up to 600 ºC No.
Higher frequency? >30MHz <10MHz
Comparison with current ultrasonic transducer
Principle
The ultrasonic wave is steered by the phased array technique.
Novel Mechanism for Generation and Receiving of Ultrasound on a Single Fiber Using Nanoparticles.
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Intellectual Merits• 1) This proposal will be the first attempt to explore
nanoparticles for photoacoustic generation in an ultrasound probe, which is expected to enhance the ultrasound generation efficiency.
• 2) The outcome of this research will open up a new avenue for research on integration of ultrasound generation and receiving on a single optical fiber tip.
• 3) The research will be the first attempt to optically steer the direction of ultrasound generated in an optical fiber which could allow fast 360-degree cross section view and defect detection in any angle.
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Relationship between CAREER goal and prior funding support
Long-term goal: leader in optical sensing
Temperature sensor (NSF)
Biosensor (MLSC)Blood
pressure sensor (CVIP)
CAREER: Ultrasound generator & receiver
Pressure sensor (ARL)
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Where Am I Now?• Grants:
– NSF CAREER Award; $400K– Massachusetts Life Sciences Center New Investigator
Matching Grant, $ 599,775. – NSF MRI ($1.15M); PI– NSF MRI ($507,980); co-PI– NSF collaborative grant; PI in UML (not lead)– Companies (Raytheon; VasoTech; etc.)
• Group: – 1 Postdoctoral Researcher; 7 Ph.D. candidates (1 Ph.D.
student graduated); 1 M.S. student; 3 REU students
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Think about…
• Where you are now?• Where do you want to go?• Which path to take?
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Listen
• Listen to Dr. ZJ Pei• Read “NSF CAREER Proposal Writing
Tips”, ZJ. Pei, http://www.lulu.com/product/paperback/nsf-career-proposal-writing-tips/703013
• Attend NSF CAREER Proposal Writing Workshop; CMMI grantee conference
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Prepare Well
• Prepare well (preliminary results; educational plans; collaboration letters; etc.)
• Listen to advice/suggestions (mentors; peers; students)
• Revise and revise
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Enjoy the Journey to the CAREER Goal
• Manage time efficiently• Get excited about research• Collaborate
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Acknowledgement
• Profs. Pei and Gao;
• UConn
• NSF
• UML colleagues
• My group members
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