TYPE1 DIABETES

Past, Present and the Future

Rabin MohantyConsultant PaediatricianBlackpool

Before Insulin

• Before insulin was discovered in 1921, everyone with type 1 diabetes died within weeks to years of its onset

JL on 12/15/22 and 2 mos later

Impact Of Insulin OnLife Expectancy By The 1940’s

Age at start of diabetes 50 30 10

Avg. age of death in 1897 58.0 34.1 11.3

Avg. age of death in 1945 65.9 60.5 45.0

Years Gained 8 26 34

Manufactured insulin, 'Iletin', United States, 1923

Newer

insulin pens

1st generation of insulin pumps

1960s

Modern Insulin Pump

Tandem’s t:slim insulin pump

What is an Artificial Pancreas?

Islet Cell Transplantation

Is Diabetes Curable?

Implantable Insulin Pumps Islet Cell Transplant Gene Therapy Stem Cell Vaccine Newer Drugs

Blackpool Paediatric Diabetes Service

140 children 4 children on insulin pumps( 2

moved) 4 new children on pumps soon CGMS monitoring 50% on Basal Bolus HbA1c falling Less complications