pain day – the basics of pain
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Pain Day – The Basics of Pain. Randall Reed PhD Director Center for Sensory Biology Professor Department of Molecular Biology and Genetics Department of Neuroscience Department of Otolaryngology – HNS. Our Senses Share Many Common Properties. The IBBS Center for Sensory Biology - PowerPoint PPT PresentationTRANSCRIPT
Pain Day – The Basics of Pain
Randall Reed PhDDirector Center for Sensory Biology
Professor
Department of Molecular Biology and Genetics
Department of Neuroscience
Department of Otolaryngology – HNS
Our Senses Share Many Common Properties
The IBBS Center for Sensory Biology
• Randall Reed - olfaction• Paul Fuchs - hearing• Michael Caterina - Pain/touch• Xinzhong Dong - Pain/touch• Craig Montell - vision/taste• Elisabeth Glowatzki - hearing• Jeremy Nathans - vision• King-Wai Yau - vision/olfaction• Angelika Doetzlhofer – hearing• Michael Deans - hearing
Classic View of the Senses The Five Senses - Provide Information
Vision Smell Taste Hearing Touch
Also Provide Protection
The Spectrum of Sensations
Pain from a Broad Perspective:
PainItchTouch
TRP Channels: Molecular Gatekeepers for the Senses
TRP Channels Mediate:
•Thermal Sensation / Pain•Taste
Some aspects of:
•Vision•Olfaction•Hearing
The Senses: Targets of Environmental Assault
Sensory Systems lie at interface between our inner and outer world – Subject to Damage
•Hearing Loss
•Burn/Itch
•Olfactory Loss
•Light Induced Damage
Key Opportunities/Practical Implications of Advances in Sensory Biology
Strategies to modulate (up or down) sensory perception (Pain/Auditory/Chemosensory)
Organization/Interaction of cells in tissues
Molecular and cellular genesis of specialized organelles
Understand processes of neuronal damage, repair and regeneration