Kym Francis FAULL

�PAGE �1�

CURRICULUM VITAE August 2015 Kym Francis FAULL Business address: Pasarow Mass Spectrometry Laboratory

Rooms 68-162A, Semel Institute David Geffen School of Medicine at UCLA 760 Westwood Plaza Los Angeles, California, USA, 90024-1759 Telephone: 310 206 7881 Facsimile: 310 206 2161 Electronic mail: Faull@chem.ucla.edu

EDUCATION B.Ag.Sc.1968, Biochemistry and Plant Physiology, University of Adelaide, Adelaide, South Australia B.Ag.Sc. with honors, 1969, Agricultural Biochemistry, University of Adelaide, Adelaide, South Australia Ph.D. 1974, Plant Physiology, University of Adelaide, Adelaide, South Australia PROFESSIONAL EXPERIENCE Present position July 1, 2012 Professor in Residence, Step V, Department of Psychiatry & Biobehavioral Sciences, UCLA, Los Angeles. Previous positions July 1, 2009 Professor in Residence, Step IV, Department of Psychiatry & Biobehavioral Sciences, UCLA, Los Angeles. July 1, 2006 Professor in Residence, Step III, Department of Psychiatry & Biobehavioral Sciences, UCLA, Los Angeles. July 1, 2003 Professor in Residence, Step II, Department of Psychiatry & Biobehavioral Sciences, UCLA, Los Angeles. July 1, 2000 Professor in Residence, Step I, Department of Psychiatry & Biobehavioral Sciences, UCLA, Los Angeles. July 1, 1998 Associate Professor in Residence, Step III, Department of Psychiatry & Biobehavioral Sciences, UCLA, LA July 1, 1998 Associate Professor in Residence, Step III, Department of Psychiatry & Biobehavioral Sciences, UCLA, LA. July 1, 1996 Associate Professor in Residence, Step II, Department of Psychiatry & Biobehavioral Sciences, UCLA, LA July 1, 1994 Associate Professor in Residence, Step I, Department of Psychiatry & Biobehavioral Sciences, UCLA, LA January 1993 Director of The Pasarow Mass Spectrometry Laboratroy, Departments of Psychiatry & Biobehavioral Sciences and

Chemistry & Biochemistry, UCLA, Los Angeles, California. July 1990 Assistant Professor in Residence, Step IV, Department of Psychiatry & Biobehavioral Sciences, UCLA, LA. 1988 - 1990 Senior Research Associate, Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine,

Stanford, California 1984 - 1987 Acting Assistant Professor, Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine,

Stanford, California 1982 - 1984 Senior Research Associate, Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine,

Stanford, California 1978 - 1982 Research Associate, Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine,

Stanford, California 1976 - 1978 Postdoctoral Research Associate, Department of Psychiatr & Behavioral Sciences, Stanford University School of

Medicine, Stanford, California 1974 - 1976 Senior Research Officer, Department of Chemistry, University of Wollongong, Wollongong, New South Wales,

Australia UCLA ORGANISED AND OTHER RESEARCH UNITS Member, Brain Reserarch Institute, Member, Molecular Biology Institute Research Affiliate, The Cotsen Institute of Archaeology at UCLA, August 2006-2007 Research Associate, Cotsen Institute of Archeology at UCLA, August 2008- Member, Ahmanson Translational Imaging Division, Department of Molecular and Medical Pharmacology, 07/14- BIBLIOGRAPHY PUBLICATIONS Peer Reviewed Manuscripts, published or in press Faull, K.F., Wallace, W. and Nicholas, D.J.D. Nitrite oxidase and nitrate reductase in Nitrobacter Agilis. Biochem J, 113:449-455, 1969. [1]

Kym Francis FAULL

�PAGE �2�

Faull, K.F., Coombe, B.G. and Paleg, L.G. Extraction and characterization of gibberellins from Hordeum vulgare L. seedlings. Aust J Plant Physiol, 1:183-189, 1974. [2] Faull, K.F., Coombe, B.G. and Paleg, L.G. Biosynthesis of gibberellins in barley and dwarf rice seedlings. Aust J Plant Physiol, 1:199-210, 1974. [3] Faull, K.F., Bolton, P., Halpern, B., Hammond, J., Danks, D.M., Hanel, R., Wilkinson, S.P., Wysocki, S.J. and Masters, P.L. Patient with a defect in leucine metabolism. N Engl J Med, 294:1013 (Letter to the Editor), 1976. [4] Faull, K.F., Schier, G.M., Schliesinger, P. and Halpern, B. The mass spectrometric identification of dipeptides in the urine of a patient suffering from chronic skin ulceration and oedema. Clin Chim Acta, 70:313-321, 1976. [5] Faull, K.F., Boulton, P.D., Halpern, B., Hammond, J. and Danks, D.M. The urinary organic acid profile associated with 3-hydroxy-3-methylglutaric aciduria. Clin Chim Acta, 73:533-559, 1976. [6] Sheffield, L.J., Schlesinger, P., Faull, K.F., Halpern, B.J., Schier, G.M., Cotton, R.G.H., Hammond, J. and Danks, D.M. Iminopeptiduria, skin ulcerations and edema in a boy with prolidase deficiency. J Pediatr, 91:578-583, 1977. [7] Danks, D.M., Hammond, J., Schlesinger, P., Faull, K., Burke, D. and Halpern, B. Trimethylaminuria: diet does not always control the fishy odor. N Engl J Med, 295:962 (Letter to the Editor), 1976. [8] Wilcken, B., Kilham, H.A. and Faull, K. Methylmalonic aciduria: a variant form of methylmalonyl coenzyme, A apomutase deficiency. J Pediatr, 91:428-430, 1977. [9] Truscott, R.J.W., Faull, K. and Augusteyn, R.C. The identification of anthranilic acid in proteolytic digests of cataractous lens proteins. Ophthal Res, 9:263-268, 1977. [10] Faull, K.F., Gan, I., Halpern, B., Hammond, J., Im, S., Cotton, R.G.H., Danks, D.M. and Freeman, R. Metabolic studies on two patients with nonhepatic tyrosinemia using deuterated tyrosine loads. Ped Res, 11:631-637, 1977. [11] Faull, K.F. DoAmaral, J.R. and Barchas, J.D. A selected ion monitoring assay for probenecid. Biomed Mass Spectrometry, 5:317-320, 1978. [12] Faull, K.F., DoAmaral, J.R., Berger, P.A. and Barchas, J.D. Mass spectrometric identification and selected ion monitoring quantitation of gamma-aminobutyric acid (GABA) in human lumbar cerebrospinal fluid. J Neurochem, 31:1119-1122, 1978. [13] Faull, K.F., Anderson, P.J., Barchas, J.D. and Berger, P.A. Selected ion monitoring assay for biogenic amine metabolites and probenecid in human lumbar cerebrospinal fluid. J Chromatogr Biomed Appl, 163:337-349, 1979. [14] Berger, P.A., Faull, K.F., Kilkowski, J., Anderson, P.J., Kraemer, H., Davis, K.L. and Barchas, J.D. CSF monoamine metabolites in depression and schizophrenia. Am J Psychiatr, 137:174-180, 1980. Published correction: Faull, K.F., Berger, P.A., Kilkowski, J., Anderson, P.J., Kraemer, H., Davis, K.L. and Barchas, J.D. Corrections to a 1980 article on CSF monoamine metabolites. Am J Psychiatr, 146:118, 1989. [15] Faull, K.F., Anderson, P.J. and Barchas, J.D. Deuterated biogenic amine metabolites: preparation of ring-deuterated 4-hydroxy-3-methoxymandelic acid. J Labelled Compounds and Radiopharmaceuticals, 18:1075-1079, 1981. [16] Davis, K.L., Faull, K.F., Hollister, L.E., Barchas, J.D. and Berger, P.A. Alterations in cerebrospinal fluid dopamine metabolites following physostigmine infusion. Psychopharmacology, 72:155-160, 1981. [17] Faull, K.F., Kraemer, H.C., Barchas, J.D. and Berger, P.A. Clinical application of the probenecid test for measurement of monoamine turnover in the CNS. Biol Psychiatr, 16:879-899, 1981. Published correction: Faull, K.F., Kraemer, H.C., Barchas, J.D. and Berger, P.A. Correction: Probenecid monoamine test. Biol Psychiatr, 24:960, 1988. [18] Davis, K.L., Hollister, L.E., Mathe, A.A., Davis, B.M., Rothpearl, A.B., Faull, K.F., Hsieh, J.Y.K., Barchas, J.D. and Berger, P.A. Neuroendo- crine and neurochemical measurements in depression. Am J Psychiatr, 138:1555-1562, 1981. [19] Faull, K.F., Barchas, J.D., Foutz, A.S., Dement, W.C. and Holman, R.B. Monoamine metabolite concentrations in the cerebrospinal fluid of normal and narcoleptic dogs. Brain Res, 242:137-143, 1982. [20]

Kym Francis FAULL

�PAGE �3�

Martin, J.T., Barchas, J.D. and Faull, K.F. Fused silica gas chromatography/negative chemical ionization mass spectrometry for determination of catecholamines and their O-methylated metabolites. Anal Chem, 54:1806-1811, 1982. [21] Faull, K.F., Guilleminault, C., Berger, P.A. and Barchas, J.D. Cerebrospinal fluid monoamine metabolites in narcolepsy and hypersomnia. Ann Neurol, 13:258-263, 1983. Published correction: Faull, K.F., Guilleminault, C., Berger, P.A. and Barchas, J.D. Cerebrospinal fluid monoamine metabolites in narcolepsy: reanalysis. Ann Neurol, 25:310-311, 1989. [22] Faull, K.F., Barchas, J.D., Murray S. and Halpern, B. Deuterated peptides: Platinum catalyzed exchange labelling of leucine enkephalin and related peptides. Biomed Mass Spectrom, 10:463-470, 1983. [23] Benson, K.L., Zarcone, V.P., Jr., Faull, K.F., Barchas, J.D. and Berger, P.A. REM sleep eye movement activity and CSF concentrations of 5-hydroxyindoleacetic acid in psychiatric patients. Psychiatr Res, 8:73-78, 1983. [24] Guilleminault, C., Faull, K.F., Miles, L. and van den Hoed, J. Posttraumatic excessive daytime sleepiness: a review of 20 patients. Neurology, 33:1584-1589, 1983. [25] Faull, K.F., Tyler, A.N., Sim, H., Barchas, J.D., Massey, I.J., Kenyon, C.N., Goodley, P.C., Mahoney, J.F. and Perel, J. Particle-induced desorption mass spectrometry with a quadrupole mass spectrometer. Anal Chem, 56:308-311, 1984. [26] Johnson, J.V., Yost, R.A. and Faull, K.F. Tandem mass spectrometry for the trace determination of tryptolines in crude brain extracts. Anal Chem, 56:1655-1661, 1984. [27] King, R., Faull, K.F., Stahl, S.M., Mefford, I.N., Thiemann, S., Barchas, J.D. and Berger, P.A. Serotonin and schizophrenia: Correlations between serotonergic activity and schizophrenic motor behavior. Psychiatr Res, 14:235-240, 1985. [28] Roth, K.A., Makk, G., Beck, O., Faull, K., Tatemoto, K., Evans, C.J. and Barchas, J.D. Isolation and characterisation of substance P, substance P 5-11 and substance K from two metastatic ileal carcinoids. Regulatory Peptides, 12:185-199, 1985. [29] Beck, O. and Faull, K.F. Extractive acylation and mass spectrometric assay of 3-methoxytyramine, normetanephrine and metanephrine in cerebrospinal fluid. Anal Biochem, 149:492-500, 1985. [30] Stahl, S.M., Faull, K.F., Barchas, J.D. and Berger, P.A. CSF monoamine metabolites in movement disorders and normal aging. Arch Neurol, 42:166-169, 1985. Published retraction: Stahl, S.M., Faull, K.F., Barchas, J.D. and Berger, P.A. Retraction (letter to the Editor). Arch Neurol, 46:1046, 1989. PMID: 2679503. [54] Stahl, S.M., Thiemann, S., Faull, K.F., Barchas, J.D. and Berger, P.A. Neurochemistry of dopamine in Huntington's dementia and normal aging. Arch Gen Psych, 43:161-164, 1986. Published retraction: Stahl, S.M., Thiemann, S., Faull, K.F., Barchas, J.D. and Berger, P.A. Retraction (letter to the Editor). Arch Gen Psych, 46:758, 1989. PMID: 2665689. [55] Faull, K.F., Zeller-DeAmicis, L.C., Radde, L., Bowersox, S.S., Baker, T.L., Kilduff, T.S. and Dement, W.C. Biogenic amine concentrations in the brains of normal and narcoleptic canines: current status. Sleep, 9:107-110, 1986. [33] Faull, K.F., Thimann, S., King, R.J. and Guilleminault, C. Monoamine interactions in narcolepsy and hypersomnia: a preliminary report. Sleep, 9:246-249, 1986. Published correction: Faull, K.F., Thimann, S., King, R.J. and Guilleminault, C. Monoamine interactions in narcolepsy and hypersomnia: reanalysis. Sleep, 12:185-186, 1989. PMID: 2711094. [34] Lorenz, R.G., Tyler, A.N., Faull, K.F., Makk, G., Barchas, J.D. and Evans, C.J. Characterization of endorphins from the pituitary of the spiny dogfish, Squalus acanthias. Peptides, 7:119-126, 1986. [31] Beck, O. and Faull, K.F. Concentrations of the enantiomers of 5-hydroxymethtryptoline in mammalian urine: implications for in vivo biosynthesis. Biochem Pharmacol, 35:2636-2639, 1986. [36] Beck, O., Repke, D.B. and Faull, K.F. 6-Hydroxymethtryptoline is naturally occurring in mammalian urine: Identification by combined chiral capillary gas chromatography and high resolution mass spectrometry. Biomed & Envir Mass Spectrometry, 13:469-472, 1986. [37] Beck, O., Faull, K.F. and Repke, D.B. Rapid hydroxylation of methtryptoline (1-methyltetrahydro-ß-carboline) in rat: Identification of metabolites by chiral gas chromatogrphy-mass spectrometry. Naunyn-Schmiedeberg's Archives Pharmacology, 333:307-312, 1986. [38]

Kym Francis FAULL

�PAGE �4�

Weitz, C.J., Lowney, L.I., Faull, K.F., Feistner, G. and Goldstein, A. Morphine and codeine from mammalian brain. Proc Natl Acad Sci, 83:9784-9788, 1986. [42] Peabody, C.A., Faull, K.F., King, R.J., Whiteford, H.A., Barchas, J.D. and Berger, P.A. CSF amine metabolites and depression. Psychiatr Res, 21:1-7, 1987. [32] Bowersox, S.S., Kilduff, T.S., Faull, K.F., Zeller-DeAmicis, L., Dement, W.C. and Ciaranello, R.D. Brain dopamine receptor levels elevated in canine narcolepsy. Brain Res, 402:44-48, 1987. [35] Goldstein, D.B., Feistner G.J., Faull, K.F. and Tomer, K.B. Plasticisers as contaminants in commercial ethanol. Alcoholism: Clinical and Experimental Research, 11:521-524, 1987. [43] Kilduff, T.S., Bowersox, S.S., Faull, K.F., Zeller-DeAmicis, L., Radeke, C.M., Ciaranello, R.D., Heller, H.C., Barchas, J.D. and Dement, W.C. Modulation of activity of the the striatal dopaminergic system during the hibernation cycle. J Neurosci, 7:2732-2736, 1987. [44] Peabody, C.A., Whiteford, H.A., Warner, M.D., Faull, K.F., Barchas, J.D. and Berger, P.A. TRH stimulation test and depression. Psych Res, 22:21-28, 1987. [45] Weitz, C.J., Faull, K.F. and Goldstein, G. Synthesis of the skeleton of the morphine molecule by mammalian liver. Nature, 330:674-677, 1987. [47] Peroutka, S.J., Pascoe, N. and Faull, K.F. Monoamine metabolites in the cerebrospinal fluid of recreational users of 3,4-methylenedimethoxy- methamphetamine (MDMA; "ecstasy"). Res Comm in Substances of Abuse 8:125-137, 1987. [82] Greene, K.A., Beck, O., Faull, K.F., and Stavinoha, W.B. Mouse brain concentrations of 3-methoxytyramine and normetanephrine: A comparison of methods of sacrifice. Neurochem Int'l, 12;47-52, 1988. [46] Faull, K.F., Bowersox, S.S., Zeller-DeAmicis, L., Maddaluno, J.F., Ciaranello, R.D. and Dement, W.C. Influence of freezer storage time on cerebral biogenic amine and metabolite concentrations and receptor ligand binding characteristics. Brain Res, 450:225-230, 1988. [80] Faull, K.F., Pascoe, N., Greene, K.A., Maddaluno, J., Lunde, J. and King, R.J. Measurement of phenylacetic acid in cerebrospinal fluid and plasma using combined gas chromatography/electron capture chemical ionization mass spectrometry. Biomed. Envir. Mass Spec, 17: 213-219, 1988. [81] Bosin, T.R. and Faull, K.F. Measurement of ß-Carbolines by high- performance liquid chromatography with flouroescence detection. J. Chromat. Biomed. Appl. 428: 229-236, 1988. [87] Weitz, C.J., Lowney, L.I., Faull, K.F., Feistner, G. and Goldstein, A. 6-Acetylmorphine: A naturalproduct present in mammalian brain. Proc Natl Acad Sci, 85: 5335-5338, 1988. [91] Bosin, T.R. and Faull, K.F. Harman in alcoholic beverages: Pharmacological and toxicological implications. Alcoholism: Clin. and Exptl. Res. 12: 679-682, 1988. [86]

Arndt, D.C., Ratner, A.V., Faull, K.F., Barchas, J.D. and Young, S.W. 19 F Magnetic resonance imaging and spectroscopy of a fluorinated neuroleptic ligand: In vivo and in vitro studies. Psych. Res. 25: 73-79, 1988. [92] Maddaluno, J.F. and Faull, K.F. Inhibition of mushroom tyrosinase by 3-amino-L-tyrosine: Molecular probing of the active site of the enzyme. Experientia 44: 885-887 (1988). [94] Bosin, T.R., Borg, S. and Faull, K.F. Harman in rat brain, lung and human CSF: Effect of alcohol consumption. Alcohol, 5: 505-511 (1989). PMID: 3245894. [85] Sharma, R., Javaid, J.I., Janicak, P., Faull, K., Comaty, J. and Davis, J.M. Plasma and CSF HVA before and after pharmacological treatment, Psy. Research, 28: 97-104 (1989). PMID: 2740469. [88] Peura, P., Johnson, J.V., Yost, R.A., and Faull, K.F. The concentrations of tryptoline and methtryptoline in rat brain. J. Neurochem, 52: 847-852 (1989). PMID: 2918311. [98]

Kym Francis FAULL

�PAGE �5�

Kim, Y.H., Orenberg, E.K., Faull, K.F., Wade-Jardetsky, N.G. and Jardetzky, O. 1H NMR Spectroscopy: An approach to evaluation of diseased skin in vivo. J Investigative Dermatology, 92:210-216, 1989. PMID: 2537364. [95] Bosin, T.R. and Faull, K.F. Indole derivatisation procedures for electron capture negative chemical ionisation mass spectrometry: Identification of 1-methyl-1,2,3,4-tetrahydro-ß-carboline in rat brain and lung. Biomed. Environ. Mass Spectrom, 18: 247-252 (1989). PMID: 2706377. [100] Greene, K.A. and Faull, K.F. Relationships between plasma and cerebrospinal fluid norepinephrine and dopamine metabolites in a non-human primate. J. Neurochem, 53:1007-1013 (1989). PMID: 2769251. [99] Feistner, G.J., Hojrup, P., Evans, C.J., Barofsky, D., Faull, K.F. and Roepstorff, P. Mass spectrometric charting of bovine posterior/intermediate pituitary peptides. Proc Natl Acad Sci, 86:6013-6017, 1989. PMID: 2762311 Faull, K.F., King, R.J., Barchas, J.D. and Csernansky, J.G. CSF phenylacetic acid and hostility in paranoid schizophrenia. Psychiatry Research, 30:111-118, 1989. PMID: 2616681. [107] Csernansky, J.G., King, R.J., Faustman, W.O., Moses, J.A., Poscher, M.E., and Faull, K.F. CSF 5-HIAA and deficit schizophrenic characteristics. British J. Psychiatry, 156:501-507, 1990. PMID: 1696842. [108] Faustman, W.O., Faull, K.F., Whiteford, H.A., Borchert, C. and Csernansky, J.G. CSF 5-HIAA, serum cortisol and age differentially predict vegetative and cognitive symptoms in depression. Biological Psychiatry, 27:311-318, 1990. PMID: 1690548. [109] Feistner, G.J., Pascoe, N., Faull, K.F., and Tomer, K.B. Gas chromatography/electron impact mass spectrometry, fast atom bombardment mass spectrometry, mass-analysed ion kinetic energy spectroscopy and B/E linked scan analysis of triarylphosphates and triethylene glycol fatty acid esters. Biomed and Environ Mass Spec, 19:151-158, 1990. PMID: 2331530 [111] Bayart, F., Hayashi, K.T., Faull, K.F., Barchas, J.D., and Levine, S. Influence of maternal proximity on behavior and physiological responses to separation in infant rhesus monkeys (Macaca mulatta). Behav. Neuroscience, 104: 98-107, 1990. PMID: 1690549. [119] Wiener, S.G., Bayart, F., Faull, K.F. and Levine, S. Behavioral and physiological responses to maternal separation in the squirrel monkey (Saimiri sciureus). Behavioral Neuroscience, 104:108-115, 1990. PMID: 1690548. [91] Miller, J.D., Faull, K.F., Bowersox, S.S. and Dement, W.C. CNS monoamines and their metabolites in canine narcolepsy: a replication study. Brain Research, 509:169-171, 1990. PMID: 1689603. [113] Maddaluno, J.F. and Faull, K.F. Fast enzymatic preparation of L-DOPA from tyrosine and molecular oxygen: a potential method for

preparing [15O]-DOPA. Applied Radiation and Isotopes, 41:873-878, 1990. PMID: 2176194. [117]. Jibson, M., Faull, K.F. and Csernansky, J.G. Intercorrelations among monoamine metabolite concentrations in human lumbar CSF are not due to a shared acid transport system. Biological Psychiatry, 28:595-602, 1990. PMID: 1699614. [115] Faull, K.F., Pascoe, N., Maddaluno, J.M., Greene, K.A., and Wiener, S. Passage from MHPG from plasma to CSF in a non-human primate. J. of Neuroscience Research, 27:533-540, 1990. PMID: 2079714. [118]. Benson, K.L., Faull, K.F. and Zarcone, V.P. Evidence for the role of serotonin in the regulation of slow wave sleep in schizophrenia. Sleep, 14:133-139, 1991. PMID: 1714097. [110] Faustman, W.O. King, R.J. Faull, K.F., Moses, J.A Jnr. Benson, K.L. Zarcone, V.P. and Csernansky, J.G. MMPI measures of impusivity and depression correlate with CSF 5-HIAA and HVA in depression but not schizophrenia. Journal of Affective Disorders 22: 235-239, 1991. PMID: 1939932. [121]. Faull, K.F. and Csernansky, J.G. Commentary: Biochemical hypotheses of depression. Integrative Psychiatry 7:165-167, 1991 [131] Faustman, W.O., Ringo, D.L. and Faull, K.F. An association between low levels of 5HIAA and HVA in cerebrospinal fluid and early mortality in a diagnostically mixed psychiatric sample. British J. Psychiatry, 163:519-521, 1993. PMID: 7504565. [138] Bickel, U., Yoshikawa, T., Landaw, E.M., Faull, K.F. and Pardridge, W.M. A vasoactive intestinal peptide analogue coupled to a brain drug delivery vector increases cerebral blood flow. Proc. Natl. Acad. Sci.., 90:2618-2622, 1993. PMID: 8385339. [134]

Kym Francis FAULL

�PAGE �6�

Stevens, R.L., Faull, K.F., Conklin, K.A., Green, B.N. and Fluharty, A.L. Porcine Cerebroside sulfate activator: further structural characterization and disulfide identification. Biochemistry, 32:4051-4059, 1993. PMID: 8471613. [136] Benson, K.L., Faull, K.F. and Zarcone, V.P. Jnr. The effects of age and serotonergic activity on slow wave sleep in depressive illness. Biological Psychiatry, 33:842-844, 1993. PMID: 7690599. [135] Sharma, R.P., Javaid, J.I., Janicak, P.G., Davis, J.M. and Faull, K.F. Homovanillic acid in cerebrospinal fluid: patterns of response to four weeks of neuroleptic treatment. Biological Psychiatry, 34:128-134, 1993. PMID: 8104508. [137] Sharma, R.P., Javaid, J.I., Faull, K.F., Davis, J.M. and Janikak, P. CSF and plasma MHPG and the CSF MHPG index: pretreatment levels in diagnostic groups and response to somatic treatments. Pschiiatry Research 51:51-60, 1993. PMID: 7910975. [139] Ringo D.L., Lindley S.E., Faull, K.F. and Faustman W.O. Cholesterol and serotonin: seeking a possible link between blood cholesterol and CSF 5-HIAA. Biological Psychiatry, 35:957-959, 1994. PMID: 7521673. [133] Csernansky, J.G., Newcomer, J.W., Jackson, K., Lombrozo, L., Faull, K.F., Zipursky, R., Pfefferbaum, A. and Faustman, W.O. The effects of raclopride treatment on plasma and CSF HVA: relationships with clinical improvements in male schizophrenics. Psychopharmacology 116:291-296, 1994. PMID: 7534423. [145] Zarcone, V.P., JR., Benson, K.L., Greene, K.A., Csernansky, J.G., and Faull, K.F. The effect of chronic alprazolam on sleep and bioamine metabolites in depression. Journal of Clinical Psychopharmacology 14:36-40, 1994. PMID: 7512100. [128] Gunderson, C., Mastrogiacomo, A., Faull, K.F. and Umback, J.A. Extensive lipidation of a Torpedo cystine string protein. Journal of Biological Chemistry 269:19197-19199, 1994. PMID: 8034679. [146] Feistner, G.F., Faull, K.F., Barofsky, D.F. and Roepstorff, P. Mass spectrometric peptide and protein charting . J. Mass Spectrometry, 30:519-530, 1995. 147] Sharma, R.P., Faull, K.F., Javaid, J.I. and Davis, J.M. Cerebrospinal fluid levels of phenylacetic acid in psychiatric illness; behavioral associations and response to neuroleptic treatment. Acta Psychiatrica Scandavica 91:293-298, 1995. PMID: 7639084. [149] Glasgow, B.J., Abduragimov, A.R., Farahbaskh, Z.T., Faull, K.F. and Hubbell, W.T. Tear lipocalins bind a broad array of lipid ligands. Current Eye Research 14:363-372, 1995. [150] Poon, W.W., Marbios, B.N., Faull, K.F. and Clarke, C.F. 3-Hexaprenyl-4-hydroxybenzoic acid forms a pool of ubiquinone intermediate in Saccharomyces cerevisiae . Archives Biochem and Biophysics, 320: 305-314, 1995. PMID: 7625838. [151] Schneewind, O., Fowler, A. and Faull, K.F. Structure of the cell wall anchor of surface proteins in Staphlococcus aureus. Science 268:103-106, 1995. PMID: 7701329. [152] Gordon, L.M., Waring, A.J., Curtain, C.C., Kirkpatrick, A., Leung, C., Faull, K.F. and Mobley, P.W. Antivirals that target the amino-terminal domain of HIV type I glycoprotein 41. AIDS Research and Human Retroviruses 11:677-686, 1995. PMID: 7576927. [154] Olmstedt, C.E., Lazareff, J.A., Olino, E.N., Fluharty, A.L., Faull, K.F., Peacock, W.J., Wehby-Grant, M.C., Geyek, R.J. and Fisher, R.S. Neuroamine related compounds in the CSF of hydrocephalic rabbits. Neuroreport 6:1769-1772, 1995. PMID: 8541478. [155] Ehrhardt, D. W., Atkinson, E.M., Faull, K.F., Freedberg, D.I., Sutherlin, D.P., Armstrong, R. and Long, S.R. In vitro sulfotransferase activity of NodH, a nodulation protein of Rhizobium meliloti , required for host specific nodulation. J. Bacteriology 177: 6237-6245, 1995. PMID: 7592390. [143] Watson, A.D., Berliner, J.A., Hama, S.Y., La Du, B.N., Faull, K.F., Fogelman, A.M. and Navab, M. Protective effect of HDL-associated paraoxonase - inhibition of the biological activity of minimally oxidised low density lipoprotein. J. Clinical Investigation 96:2882-2891, 1995. PMID: 8675659. [153]. Waring, A.J. Faull, K.F., Leung, C., Chang-Chien, A., Mercado, P., Taeusch., H.W. and Gordon, L.M. Synthesis, secondary structure and folding of the bend region of lung surfactant protein B. Peptide Research, 9:938-946, 1996. PMID: 8727481. [156] Spannagel, A.W., Green, G.M., Guan, D., Liddle, R.A., Faull, K.F. and Reeve, J.R. Purification and characterization of a luminal cholecystokinin-releasing factor from rat intestinal secretion. Proc. Natl, Acad Sci (USA) 93:4415-4420, 1996. PMID: 8633081. [167]

Kym Francis FAULL

�PAGE �7�

Gordon, L.M., Horvath, S., Longo, M.L., Zasadinski, J.A.N.., Taeusch, H.W., Faull, K.F., Leung, C. and Waring, A.W. Conformation and molecular topography of the N-terminal segment of surfactant protein B in structure-promoting environments. Protein Science 5:1662-1675, 1996. PMID: 8844855. [165] Watson, A.D., Leitinger, N., Navab, M., Faull, K.F., Horkko, S., Witztum, J.L., Palinski, W., Schwenke, D., Salomon, R.G., Sha, W., Subbanagounder, G., Fogelman, A.M. and Berliner, J.A. Structural identification by mass spectrometry of oxidised phospholipids in minimally oxidised low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo. Journal of Biological Chemistry 272:13597-13607, 1997. PMID: 9153208. [163] Zhao, K-W., Faull, K.F. , Kakkis, E.D. and Neufeld, E.F. Carbohydrate structures of recombinant human alpha-L-Iduronidase secreted by chinese hamster ovary cells. Journal of Biological Chemistry, 272:22758-22765, 1997. PMID: 9278435. [158] Ton-That, H., Faull, K.F. and Schneewind, O. Anchor structure of staphyloccal surface proteins: a branched tetra-peptide that links the carboxyl terminus of proteins to the cell wall peptidoglycan. Journal of Biological Chemistry, 272:22285-22292, 1997. PMID: 9268378. [171] Vigna, S.R., Faull, K.F., and Reeve, J.R. Purification, amino acid sequence, synthesis and receptor selectivity of Alligator gastrin. General and Comparative Endocrinology, 108:316-326, 1997. PMID: 9356227. [161] Waring A.J., Chen, Y., Faull, K.F., Stevens, R, .Sherman, M.A. and Fluharty, A.L. Porcine cerebroside sulfate activator (Saposin B) secondary structure: CD, FTIR and NMR strudies. Molecular Genetics and Metabolism, 63:14-25, 1998. PMID: 9538512. [159] Glasgow, B.J., Abduragimov A.R., Yusifov, T.N., Gassymov, O.K., Horwitz, J., Hubbell, W.L., and Faull, K.F. Characterization of the disulfide motif and secondary structure of tear lipocalins. Biochemistry, 37:2215-2225, 1998. PMID: 9485367. [169] Faull, Kym F., Gottfried J. Feistner, Kenneth Conklin , Peter Roepstorff and Philip C. Andrews. Revised primary structures of rat pituitary (-LPH and (-endorphin. Neuropeptides, 32:339-349, 1998. PMID: 9894577. [174] Whitelegge, J., P., Gunderson, C.B. and Faull, K.F. Electrospray-ionization mass spectrometry of intact intrinsic membrane proteins. Protein Science 7:1423-1430, 1998. PMID: 9655347. Navarre, W.W., Ton-That, H., Faull, K.F. and Schneewind, O. Anchor structure of Staphlococcal surface proteins II. COOH-terminal structure of muramidase and amidase-solubilized surface protein. J. Biological Chemistry, 273:29135-29142, 1998. PMID: 9894577. [180]. Leitinger, N., Watson, A.D., Hama, S.Y., Ivandic, B., Qiao, J-H., Huber, J., F., Faull, K.F., Grass, D.S., Navab, M., Fogelman, A.M., deBeer, F.C., Lusis, A.J. and Berliner, J.A. Role of group II secretory PLA2 in atherosclerosis: 2. Potential involvement of

biologically active oxidised phospholipids. Atherosclerosis, Thrombosis and Vascular Biology, 19:1291-1298, 1999. PMID: 10323782. [170] Faustman, W.O., Bardgett, M., Faull, K.F., Pfefferbaum, A. and Csernansky, J.G. Cerebrospinal fluid glutamate inversely correlates with positive symptom severity in unmedicated male schizophrenic/schizoaffective patients. Biological Psychiatry, 45:68-75, 1999. PMID: 9894577. [160] Greer, A., Conklin, K.A., Faull, K.F., Houk, K.N. and Foote, C.S. Low temperature FAB and mass spectrometric identification of unstable episulfoxides. PMID: 11674198. [184] Navarre, W.W., Ton-That, H., Faull, K.F. and Schneewind, O. Multiple enzymatic activities of the murein hydrolase from Staphyloccal phage ø11. Identification of a D-alanyl-glycine endopeptidase activity. J. Biological Chemistry, 274: 15847-15856, 1999. PMID: 10336488. [188] Faull, K.F., Rafie, R, Pascoe, N., Marsh, L. and Pfefferbaum, A. N-Acetylaspartic acid (NAA) and N-acetylaspartylglutamicacid (NAAG) in human ventricular, sub-arachnoid and lumbar cerebrospinal fluid. Neurochemical Research, 24:1249-1261, 1999. PMID: 10492520. [144] Kalhor, H.R., Niewmierzycka, A. Faull, K.F., Yao, X., Grade, S., Clarke, S. and Rubenstein, P.A. A highly conserved 3-methylhistidine modification is absent in yeast actin Archives of Biochemistry and Biophysics: 370: 105-111, 1999. PMID: 10496983. [190]

Kym Francis FAULL

�PAGE �8�

Fluharty, A.L., Lombardo, C., Louis, A., Stevens, R.L., Whitelegge, J., Waring, A.J.., To, T., Fluharty, C.B. and Faull, K.F. Preparation of the cerebroside sulfate activator (CSAct or Saposin B) from human urine. Molecular Genetics and Metabolism: 68:391-402, 1999. PMID: 10562467. [186] Faull, K.F., Whitelegge, J.P., Higginson, J., Waring, A.J., To, T., Johnson, J., Krutchinsky, A.N., Standing, K.G., Stevens, R.L., Fluharty, C.B. and Fluharty, A.L. Cerebroside sulfate activator protein (Saposin B): Chromatographic and electrospray mass spectrometric properties. Journal of Mass Spectrometry: 34:1040-1054, PMID: 10510427. [182] Whitelegge, J.P., le Coutre, J., Lee, J.C., Engel, C.K., Privé, G.G., Faull, K.F. and Kaback, H.R. Towards the bilayer proteome: Electrospray ionization mass spectrometry of large intact membrane proteins. Proc. Natl, Acad Sci (USA). 96:10695-10698, 1999. PMID: 10485888. Watson, A.D., Subbanagounder, G., Welsbie, D.S., Faull, K.F., Navab, M., Jung, M.E., Fogelman, A.M. and Berliner, J.A. Structural identification of a novel pro-inflammatory epoxyisoprostane phospholipid in mildly oxidized low-density lipoprotein. Journal of Biological Chemistry 274: 24787-24798, 1999. PMID: 10455151.183] Subbanagounder, G., Leitinger, N., Shih, P.T., Faull, K.F. and Berliner, J.A. Evidence that phospholipid oxidation products and/or plarelet-activating factor play an important role in early atherogenesis: In vitro and in vivo inhibition by WEB 2086. Circulation Research 85: 311-318, 1999. PMID: 10455059. [185]. Ton-That, H., Liu, G., Mazmanian, S.K., Faull, K.F. and Schneewind, O. Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif. Proc. Natl, Acad Sci (USA) 96:12424-12429, 1999. PMID: 10535938. [192]. Maddaluno, J. and Faull, K.F. Mass spectrometric characterization of Limulus polyphemus hemocyanin. Biochemical and Biophysical Research Communications 264:883-890, 1999. PMID: 10544025. [197] Faull, K.F., Higginson, J., Waring, A.J., To, T., Whitelegge, J.P., Stevens, R.L., Fluharty, C and Fluharty, A.L. The hydrogen/deuterium exchange signature of porcine cerebroside sulfate activator protein. Journal of Mass Spectrometry 35: 392-401, 1999. PMID: 10767769. [179] Marbois B., M., Faull, K. F., Fluharty, A.L., Raval-Fernandes, S., and Rome, L. Analysis of sulfatide from rat cerebellum and multiple sclerosis white matter by negative ion electrospray mass spectrometry. Biochemica et Biophysica Acta, 1484:59-70, 2000. PMID: 10685031. [187] Howard, D.H., Rafie, R., Tiwari, A. and Faull, K.F. Hydroxamate siderophores of Histoplasma capsulatum. Infection and Immunity. 68:2338-2343, 2000. PMID:10722639. [195] Dhar, G., Faull, K.F. and Schneewind, O. Anchor structure of Listerial surface proteins. An amide bond links the COOH-terminal threonine of internalin A to the (-ramino of diaminopimelic acid within branched cell wall tetra peptides. Biochemistry, 39:3725-3733, 2000. PMID: 10736172. [196] Ton-That, H., Mazmanian, S.K., Faull, K.F. and Schneewind, O. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. I.. Sortase catalyzed in vitro transpeptidation reaction using LPXTG peptide and NH2-Gly3 substrates. Journal of Biological Chemistry,275:9876-9881, 2000. PMID: 10734144. [198] Faull, K.F., Higginson, J., Waring, A.J., To, T., Stevens, R.L., Whitelegge, J.P., Fluharty, C.B. and Fluharty, A.L. Disulfide connectivity in cerebroside sulfate activator is not necessary for biological activity but is necessary for tertiary structure. Archives of Biochemistry and Biophysics 376: 266-274, 2000. PMID: 10775412. [191] le Coutre, J., Whitelegge, J.P., Gross, A., Turk, E., Wright, E.M., Kaback, H.R.. and Faull, K.F. Proteomics on full-length membrane proteins using mass spectrometry. Biochemistry 39:4237-4242, 2000. PMID: 10757971. [200] Shih, D.M., Xia, Y-R., Wang, X-P., Miller, E., Castellani, L.W., Subbanagounder, G., Cheroutre, H., Faull, K.F., Berliner, J.A., Witzum, J.L. and Lusis, AJ. Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis. Journal of Biological Chemistry, 275:17527-17535, 2000. PMID: 10748217. [204] Turk, E., Kim, O., le Coutre, J., Whitelegge, J.P., Eskandari, S., Lam, J.T., Kreman, M., Zampighi, G., Faull, K.F. and Wright, E.M.. Molecular characterization of Vibrio parahaemolyticus vSGLT: a model for sodium-coupled sugar cotransporters. .Journal of Biological Chemistry, 275:25711-25716, 2000. PMID: 10835424. [203]

Kym Francis FAULL

�PAGE �9�

Whitelegge, J.P., Penn, B., To, T., Johnson, J., Waring, A.J., Sherman, M., Stevens, R.L., Fluharty, C.B., Faull, K.F., and Fluharty, A.L. Methionine oxidation within the cerebroside sufate activator protein (CSAct or Saposin B). Protein Science, 9;1618-1630, 2000. PMID: 11045609. [181] Liu, H.,, Zhu, H., Eggers, D.K., Nersissian, A., Faull, K.F., Goto, J.J., Ai, J., Sanders-Loehr, J., Gralla, E.B. and Valentine, J.S. Copper (2+) binding to the surface residue cystine 111 of His46Arg human copper-zinc superoxide dismutase, a familial amytrophic lateral sclerosis mutant. Biochemistry, 39:8125-8132, 2000. PMID: 10889018. [201] Subbanagounder G., Leitinger, N., Schwenke, D.C., Wong, J,W., Lee, H., Rizza, C., Watson, A.D., Faull, K.F. Fogelman, A.M. and Berliner, J.A. Determinants of the bioactivity of oxidized phospholipids: specific oxidized fatty acyl groups at the sn-2 position. Atherosclerosis, Thrombosis and Vascular Biology, 20:2248-2254, 2000. PMID: 11031211. [175] Faull, K.F., Johnson, J., Kim, M.J., To, T., Whitelegge, J.P., Stevens, R.L., Fluharty, C.B. and Fluharty, A.L. Structure of the asparagine-linked sugar chains of porcine kidney and human urine cerebroside sulfate activator protein. Journal of Mass Spectrometry, 35:1416-1424, 2000. PMID: 11180632. [205] Navab, M., Hama, S.Y., Cooke, C.J., Anantharamaiah, G.M., Hassan, K., Hough, G.P., Watson, A.D., Reddy, S.T., Sevanian, A., Fonarow, G.C. and Fogelman, A.M. Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: Steps 2 and 3. Journal of Lipid Research 41:1495-1508, 2000. PMID: 10974056. [235]. Navab, M., Hama, S.Y., Anantharamaiah, G.M., Chaddha, M., Jin, L., Subbanagounder, G, Faull, K.F., Reddy, S.T., Miller, N.E. and Fogelman, A.M. Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: Step 1. Journal of Lipid Research 41:1481-1494, 2000. PMID: 10974056. [217]. Fluharty, C.B., Johnson, J., Whitelegge, J.P., Faull, K.F. and Fluharty, A.L. A comparative lipid binding study on the cerebroside sulfate avtivator (saposin B). Journal of Neuroscience Research, 63:82-89, 2001. PMID: 11169617. [199] Norris, A.J., Whitelegge, J.P., Faull, K.F. and Toyokuni, T. Analysis of enzyme kinetics using electropsray ionization mass spectrometry and multiple reaction monitoring: Fucosyltranssfersae V. Biochemistry 40:3774-3779, 2001. PMID: 11300757. [216] Butterfield, L.H., Meng, W. S., Koh, A., Vollmer, C.M., Ribas, A., Dissette, V.B., Faull, K., Glaspy, J.A., McBride, W.H. and Economou, J.S. T cell responses to HLA-A*0201-restricted peptides derived from human alpha fetoprotein. J. Immunology, 166:5300-5308, 2001. PMID: 11290817. [202] Suhr, S.T., Senut, M-C., Whitelegge, J.P., Faull, K.F., Cuizon, D.M., and Gage, F.H. Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression. The Journal of Cell Biology 153:283-284, 2001. PMID: 11309410. [214] Zhong, L-t., Manzi, A., Skowronski, E., Notterpek, L., Fluharty, A.L., Faull, K.F., Masada, I., Rabizadeh, S., Varsanyi-Nagy, M., Ruan, Y., Oh, J., Butcher, L.L. and Bredeson, D.E. A monoclonal antobody that induces neuronal apoptosis binds a metastasis marker. Cancer Research 61: 5741-5748, 2001. PMID: 11479210. [157] Keire, D., Anton, P., Faull, K.F., Ruth, E., Walsh, J.H., Chew, P., Quisimoro, D., Territo, M. and Reeve, J.R.Jr. Diethylphthalate, a chemotactic factor secreted by H. pylori. Jounal of Biological Chemistry, 276: 48847-48853, 2001. PMID:11677249. [207] Norris, A.J., Whitelegge, J.P., Faull,

K.F. and Toyokuni, T. Kinetic characterization of enzyme inhibitors using electrospray-ionization

mass spectrometry coupled with multiple reaction monitoring. Analytical Chemistry, 73: 6024-6029, 2001. PMID: 11791575. [222] Gómez, S.M., Nishio, J.M., Faull, K.F. and Whitelegge, J.P. The chloroplast grana proteome defined by intact mass measurements from liquid chromatography mass spectrometry. Molecular and Cellular Proteomics, 1:46-59, 2002 PMID: 12096140. [219] Subbanagounder G, Wong JW, Lee H, Faull KF, Miller E, Witztum JL and Berliner, JA. Epoxyisoprostane and Epoxycyclopentenone Phospholipids Regulate Monocyte Chemotactic Protein-1 and Interleukin-8 Synthesis: Formation of These Oxidized Phospholipids in Response to Interleukin-1. Journal of Biological Chemistry 277:7271-7281, 2002. PMID: 11751881. [223] Whitelegge, J.P., Gómez, S.M., Aguilera, R., Roberson, R.W., Vermaas, W.F., Crother, T.R., Champion, C.I., Nally, J.E., Blanco, D.R., Lovett, M.A., Miller, J.N. and Faull, K.F. Identification of proteins and intact mass measurements in proteomics. Applied Genomics and Proteomics 1:13-22, 2002. [225] Jonassen, T., Marbois, B.N., Faull, K.F., Clarke, C.F. and Larsen, P.L. Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria. J. of Biological Chemistry 277:45020-45027, 2002. PMID: 12324451. (224).

Kym Francis FAULL

�PAGE �10�

Ahn, V.E., Faull, K.F., Whitelegge, J.P., Higginson, J. , Fluharty, A.L. and Privé, G.G. Expression, purification, crystallization and preliminary X-ray analysis of recombinant human saposin B. Protein Expression & Purification 27:186-193, 2003. PMID: 12510003. [221] Whitelegge, J.P., Gómez, S.M. and Faull, K.F. Proteomics of membrane proteins. Advances in Protein Chemistry volume 65, Proteome Characterization and Proteomics, edited by Richard D. Smith and Timothy D. Veenstra, Academic Press pp 271-304, 2003. PMID: 12964373. [211] Ahn, V.E., Faull, K.F., Whitelegge, J.P., Fluharty, A.L. and Privé, G.G. Crystal structure of saposin B reveals a dimeric shell for lipid binding. Proc. Natl, Acad Sci (USA) 100:38-43, 2003. PMID: 12518053. [227] Kim, D.H., Marbois, B.N., Faull, K.F. and Eckhert, C.D. Esterification of borate with NAD

+ and NADH as studied by ESI-MS and

11BNMR spectroscopy. Journal of Mass Spectrometry 38:632-640, 2003. PMID: 12827632. [236]

Weinglass, A.B., Whitelegge, J.P., Hu, Y., Verner, G.E., Faull, K.F. and Kaback, H.R. Exploiting mass spectrometry to elucidate substrate binding interactions in a membrane transport protein. EMBO Journal. 22:1467-1477, 2003. PMID: 12660154. [232] Shau, H., Chandler, G.S., Whitelegge, J.P., Gornbein, J.A., Faull, K.F. and Chang, H.R. Proteomic profiling of cancer biomarkers. Briefings in Functional Genomics and Proteomics 2:147-158, 2003. PMID: 15239937. [233] Whitelegge, J.P., Ahn, V., Norris, A.J., Sung, H., Johnson, J., Waring, A.J., Stevens, R.L., Fluharty, C.B., Prive, G., Faull, K.F. and Fluharty, A.L. Characterization of a recombinant molecule covalently indistinguishable from human Cerebroside-Sulfate Activator Protein (CSAct or Saposin B). Cellular and Molecular Biology 49: 799-807, 2003. PMID: 14528917. [212] Chen, F., Ng, P-S., Faull, K.F. and Lee, R.H. Cone photoreceptor ((-transducin: post-translational modification and interaction with phosducin. Investigative Opthalmology and Vision Research 44:4622-4629, 2003. PMID: 14578377 [213]. Norris, A.J., Whitelegge, J.P., Strouse, J.M., Faull, K.F. and Toyokuni, T. Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: Implication for the reaction mechanism. Bio-organic and Medicinal Chemistry Letters 14:571-573, 2004. PMID: 14741245. [231]. Woo, H.H., Faull, K.F., Hirsch, A.M. and Hawes, M.C. Altered life cycle in Arabidopsis plants expressing PsUGT1, a UDP-glucuronosyltransferase-encoding gene from pea. Plant Physiol. 133:538-548, 2003. PMID: 12972656. [243] Gómez, S. M., Bil, K.Y., Aguilera, R., Nishio, J.N., Faull, K.F. and Whitelegge, J.P. Transit peptide cleavage sites of integral thylakoid membrane proteins. Mol Cell Proteomics 10:1068-1085, 2003. PMID: 12902551. [234]

Katz, J.E., Darren S. Dumlao, Jacob I. Wasserman, Michael E. Jung, Kym F. Faull, Steven Clark. 3-Isopropylmalate is the Major Endogenous Substrate of the Saccharomyces cerevisiae TMT1 trans-Aconitate Methyltransferase. Biochemistry 43:5976-5986, 2004. PMID: 15147181. [241]. Kim, Danny H., Kym F. Faull, Andrew J. Norris, Curtis D. Eckhert. Borate-nucleotide complex formation depends on charge and phosphorylation state. Journal of Mass Spectrometry 39, 743-751, 2004. PMID: 15282753. [239] Whitelegge, J.P., Katz, J.E., Pihakari, K.A., Hale, R., Aguilera, R., Gómez, S.M., Faull, K.F., Vavilin, D. and Vermass, W. Subtle modification of isotope ratio proteomics; an integrated strategy for expression proteomics. Phytochemistry 65:1507-1515, 2004. PMID: 15276448. [243] Reeve JR Jr, Wu SV, Keire DA, Faull K, Chew P, Solomon TE, Green GM, Coskun T. Differential bile-pancreatic secretory effects of CCK-58 and CCK-8. Am J Physiol Gastrointest Liver Physiol. 286: G395-402, 2004. PMID: 14604858. [228] Blanco, D.R., C.I. Champion, A.N. Dooley, D.L. Cox, J.P. Whitelegge, K.F. Faull, M.A. Lovett. Isolation of a Monoclonal Antibody Against a Novel and Specific Polyphosphatidylcholine Surface Antigen of Treponema pallidum that has Killing Activity and Confers Passive Immunity in Experimental Rabbit Syphilis. Infection and Immunity 73: 3083-3095, 2005. PMID: 15845516. [252]. Weinglass, A., Whitelegge, J.P., Faull, K.F., Kaback, H.R. Monitoring conformational re-arrangements in the substrate-binding site of a membrane transport protein by mass spectrometry. Journal of Biological Chemistry, 279: 41858-65, 2004. PMID: 15272008. [292]

Kym Francis FAULL

�PAGE �11�

Marbois B, Gin P, Faull KF, Poon WW, Lee PT, Strahan J, Shepherd JN, Clarke CF. Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q. Journal of Biological Chemistry. 280: 20231-0238 (2005). PMID: 15792955. [248] Weinglass, Adam. B., Misha Soskine, Jose-Luis Vazquez-Ibar, Julian P. Whitelegge, Kym F. Faull, H. Ronald Kaback and

Shimon

Schuldiner. Exploring the role of a unique carboxyl residue in substrate binding to EmrE by mass spectrometry. Journal of Biological Chemistry. 280: 7487-7492, 2005. PMID: 15623511. [246] Rodriguez, Jorge, Bryan Francis Shaw, Armando Durazo, Se Hui Sohn, Peter A. Doucette, Aram M. Nersissian, Kym F. Faull, Daryl K. Eggers, Ashutosh Tiwari, Lawrence J. Hayward, and Joan Selverstone Valentine. Destabilization of apoprotein is insufficient to explain Cu,Zn-superoxide dismutase-linked ALS pathogenesis. Proc. Natl. Acad. Sci. 102:10516-10521, 2005. PMID: 16124040. [247] Pekary, A. Eugene, Kym F. Faull, Mark Paulson, Robert L. Lloyd and Albert Sattin. TRH-like antidepressant peptide, pyroglutamyltyrosylprolineamide, occurs in rat brain. Journal of Mass Spectrometry 40: 1232-1236. PMID: 16124040. [256] Kang, Mo, Reuben H Kim, Ki-Hyuk Shin, Weiguong Zhong, Kym F Faull and No-Hee Park. Senescence-associated decline in the intranuclear accumulation of hOGG1 and impaired 8-oxo-dG repair activity in senescing normal human oral keratinocytes. Experimental Cell Reserch 310:186-195, 2005. PMID: 16122734. [251] Norris, Andrew J., Julian P. Whitelegge, Arman Yaghoubian, Jean-Rene Alattia, Gilbert G. Privé, Tatsushi Toyokuni, Hubert Sun, Mai N. Brooks, Luigi Panza, Pamela Matto, Federicam Compostella, Natascha Remmel, Ralf Klingenstein, Konrad Sandhoff, Claire Fluharty, Arvan Fluharty and Kym F. Faull. A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A. Journal of Lipid Research 46:2254-2264, 2005. PMID: 16061947. [258] Kozak, Katherine R., Feng Su, Julian P. Whitelegge, Kym Faull, Srinivasa Reddy and Robin Farias-Eisner. Characterization of serum biomarkers for detection of early stage ovarian cancer. Proteomics 5: 4589-4596, 2005. PMID: 16237736. [244] Kim,

Danny H., Shane Que Hee,

Andrew J. Norris, Kym F. Faull and Curtis D. Eckhert

. Boric acid inhibits adenosine diphosphate-

ribosyl cyclase non-competitively. Journal of Chromatography A, 1115: 246–252, 2006 PMID: 16545389. [260] Shaw, Bryan Francis, Armando Durazo, Aram M. Nersissian, Julian P. Whitelegge, Kym F. Faull, and Joan Selverstone Valentine. Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry. Journal of Biological Chemistry 281: 18167-18176, 2006 PMID: 16644738. [265] Mitrirattanakul, Somsak, Navapoln Ramakul, André V Guerrero, Yoshizo Matsuka, Takeshi Ono, Hirotate Iwase, Ken Mackie, Kym F Faull, Igor Spigelman. Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain 126:102-114, 2006. PMID: 16844297. [245] Barnard H., A.N. Dooley and K.F. Faull. New data on the Eastern Desert Ware from Sayala (Lower Nubia) in the Kunsthistorisches Museum, Vienna. Ägypten und Levante 15: 49-64, 2006. [253] He, Jianbo, Jeffrey Gornbein, Dejun Shen, Ming Lu, Leonor E. Rovai, Hungyi Shau, John Katz, Julian P. Whitelegge, Kym F. Faull

and Helena R. Chang. Detection of breast cancer biomarkers in nipple aspirate fluid by SELDI-TOF and their identification by

combined liquid chromatography-tandem mass spectrometry. The International Journal of Oncology 30:145-154, 2007. PMID: 17143523. [238] itrir tt u s t r pez-Valdés, Jing Liang, Yoshizo Matsuka, Ken Mackie, Kym F Faull, Igor Spigelman. Bi-directional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawl and dependance. Alcoholism: Clinical and Experimental Research 31: 855-867, 2007. PMID:17386072. [263] Tanphaichitr Nongui, Kym F. Faull, Arman Yaghoubian and Hongbin Xu. Lipid rafts and sulfogalactosylglycerolipid (SGG) in sperm functions: consensus and controversy. Trends in Glycoscience and Glycotechnology 19: 67-83, 2007. [275] Waldron, Richard T., Julian Whitelegge, Kym Faull and Enrique Rozengurt. Identification of a novel phosphorylation site in c-jun directly targeted by protein kinase D. Biochem Biophys Research Communications 356:361-367, 2007. PMID: 17359934. [271] Potter, Soshanna Zittin, Haining Zhu, Bryan Francis Shaw, Jorge A. Rodriguez, Peter A. Doucette, Se Hui Sohn, Armando Durazo, Kym F. Faull, Edith Butler Gralla, Aram M. Nersissian, and Joan Selverstone Valentine. Binding of a single zinc ion to one subunit of copper-zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein. Journal of the American Chemical Society 129: 4575-4583, 2007. PMID: 17381088. [269]

Kym Francis FAULL

�PAGE �12�

Lanigan-Gerdes

, Sara, Alek N. Dooley, Kym F. Faull, and Beth A. Lazazzera. Identification of subtilisin, Epr, and Vpr as Enzymes that

Produce CSF, an Extracellular Signaling Peptide of Bacillus. subtilis. Molecular Microbiology. 65: 1321-1333, 2007. PMID: 17666034. [266] Whitelegge

, Julian P., Vlad Zabrouskov, Frédéric Halgand, Puneet Souda, Sara Bassilian, Weihong Yan, Larry Wolinsky, Joseph A.

Loo, David T. W. Wong, Kym F. Faull..

Protein-sequence polymorphisms and post-translational modifications in proteins from human saliva using top-down Fourier-transform ion cyclotron resonance mass ppectrometry. The International Journal of Mass Spectrometry. 268: 190-197, 2007. PMID: 19050733. [277] Fujishige, Nancy A., Michelle R. Lum, Peter L. De Hoff, Julian P. Whitelegge, Kym F. Faull, and Ann M. Hirsch. Rhizobium common nod genes are required for biofilm formation. Molecular Microbiology. 10: 1365-2958, 2007. PMID: 18086203. [276] Grintsevich, Elena, E., Sabrina A. Benchaar, Dora Warshaviak, Pinmanee Boontheung, Frédéric Halgand, Julian P. Whitelegge, Kym F. Faull, Rachel R. Ogorzalek Loo, David Sept, Joseph A. Loo, and Emil Reisler. Mapping the cofilin binding site on yeast G-actin by chemical cross-linking. Journal of Molecular Biology. 377:395-409, 2008. PMID: 18258262. [281] Franchini, Laura, Luigi Panza, Kessiri Kongmanas, Nongnuj Tanphaichit, Kym F. Faull and Fiamma Ronchetti. An efficient and convenient synthesis of deuterium-labelled seminolipid isotopomers and their ESI-MS characterization. Chemistry and Physics of Lipids, 152: 78-85, 2008. PMID: 18319057. [279] Denny, Paul; Hagen, Fred; Hardt, Markus; Liao, Lujian; Yan, Weihong; Arellano, Martha; Bassilian, Sara; Bedi, Gurrinder; Boontheung, Pinmannee; Cociorva, Daniel; Delahunty, Claire; Denny, Trish; Dunsmore, Jason; Faull, Kym; Gilligan, Joyce; Gonzalez-Begne, Mireya; Halgand, Frédéric; Hall, Steven; Han, Xuemei; Henson, Bradley; Hewel, Johannes; Hu, Shen; Jeffrey, Sherry; Jiang, Jiang; Loo, Joseph; Loo, Rachel; Malamud, Daniel; Melvin, James; Miroshnychen, Olga; Navazesh, Mahvash; Niles, Richard; Park, Sung Kyu; Prakobphol, Akraporn; Ramachandran, Prasanna; Richert, Megan; Robinson, Sarah; Sondej, Melissa; Souda, Puneet; Sullivan, Mark; Takashima, Jona; Than, Shawn; Wang, Jianghua; Whitelegge, Julian; Witkowska, H.; Wolinsky, Lawrence; Xie, Yongming; Xu, Tao; Yu, Weixia; Ytterberg, Jimmy; Wong, David; Yates, John; Fisher, Susan. The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J. Proteome Research. 7:1994-2006, 2008. PMID: 18361515. [284] Anupriwan, Araya, Matthias Schenk, Kessiri Kongmanas, Rapeepun Vanichviriyakit, Daniela Costa Santos, Arman Yaghoubian, Fang Liu, Alexander Wu, Trish Berger, Kym F. Faull, Porncharn Saitongdee, Prapee Sretarugsa, and Nongnuj Tanphaichitr. Presence of Arylsulfatase A and Sulfogalactosylglycerolipid in Mouse Ovaries: Localization to the Corpus Luteum. Endocrinology, 149:3942-3951, 2008. PMID: 18420734. Lu M, Faull K.F, Whitelegge J.P, He J, Shen D, Saxton RK, Chang HR. Proteomics and Mass Spectrometry for Cancer Biomarker Discovery. Biomarker Insights 2:347-360, 2007. PMID: 19662217. [268]

Begum, Aynun, Mychica R. Jones, Giselle P. Lim, Takashi Morihara, Peter Kim, Dennis D. Heath, Cheryl L. Rock, Mila A. Pruitt, Fusheng Yang, Beverly Hudspeth, Shuxin Hu, Kym F. Faull, Bruce Teter, Greg M. Cole, and Sally A. Frautschy. Curcumin structure-function, bioavailability, and Wang

, Dorothy, Veena S. Mysore, Kerry Stevenson, Christopher Tang, Baran Ho, Jeffrey D. Suh, Victor

M. Duarte, efficacy in models of neuroinflammation and Alzheimers. Journal of Pharmacology and Experimental Therapeutics. 326: 196-208, 2008. PMID: 18417733. [283] Faull, Kym F., Kapil Mehta, Eri Srivatsan, Marilene B. Wang

. Liposome encapsulated curcumin suppresses growth of HNSCC in vitro

d i xe gr fts thr ugh the i hibiti f NFқB by AKT i depe de t p thw y. Clinical Cancer Research. 14: 6228-6236, 2008. PMID: 18829502. [289] Do, Thai, Q., Safiehkhatoon Moshkani, Patricia Castillo, Suda Anunta, Adelina Pogosyan, Annie Cheung, Beth Marbois, Kym F. Faull, William Ernst, Su Ming Chiang, Gary Fujii, Catherine F. Clarke, Krishna Foster, and Edith Porter. Lipids Including cholesteryl linoleate and cholesteryl arachidonate contribute to the inherent antibacterial activity of human nasal fluid. Journal of Immunology. 181: 4177-4187, 2008. PMID: 18768875. [271] Budzik, Jonathan M., Luciano A. Marraffini, Julian P. Whitelegge, Kym F. Faull, and Olaf Schneewind

. Inter- and intramolecular

bonds assemble pili of Gram-positive bacteria. Proceedings of the National Acadamy of Sciences (USA). 105: 10215-10220, 2008. PMID: 18621716. [286] Lanigan-Gerdes, Sara, Geraldine Briceno, Alek N. Dooley, Kym F. Faull, and Beth A. Lazazzera. Identification of residues important for cleavage of the extracellular signaling peptide, CSF, of B. subtilis fr its’ pre urs r pr tei . Journal of Bacteriology. 190: 6668-6675, 2008. PMID: 18689487. [290]

Kym Francis FAULL

�PAGE �13�

Fujishige NA, Lum MR, De Hoff PL, Whitelegge JP, Faull KF, Hirsch AM. (2008) Rhizobium common nod genes are required for biofilm formation. Mol Microbiol. 67:504-15, 2008. PMID: 18086203. [293] Keire, David A., Julian P. Whitelegge, Sara Bassilian, Kym F. Faull, Brian W. Wiggins, Omid B. Mehdizadeh, Roger D. Reidelberger, Alvin C. Haver, Ayman I. Sayegh, and Joseph R. Reeve Jr. A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36). Regulatory Peptides. 151:61-70, 2008. PMID: 18501442. [287] Bulkacz J, Faull K.F. Multiple extracellular phospholipase activities from Prevotella intermedia. Anaerobe 15:91-94, 2009. PMID: 19150408. [291] Wang Y, Lin WY, Liu K, Lin RJ, Selke M, Kolb HC, Zhang N, Zhao XZ, Phelps ME, Shen CK, Faull KF, Tseng HR. An integrated microfluidic device for large-scale in situ click chemistry screening. Lab on a Chip. 9:2281-5, 2009. PMID: 19636457 [298] He, Jianbo, Dejun Shen, Debra U. Chung, Romaine E. Saxton, Julian P. Whitelegge, Kym F. Faull, and Helena R. Chang. Tumor proteomic profiling predicts the susceptibility of breast cancer to chemotherapy. International Journal of Oncology 35:683-692, 2009. PMID: 19724903. [288] Whelan, Stephan A., Ming Lu, Jianbo He, Weihong Yan, Romaine E. Saxto, Kym F. Faull, Julian P. Whitelegge and Helena R. Chang. Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers. Journal of Proteome Research. 8:4151-60, 2009. PMID:19522481. [297] Oliveira, Débora L., Leonardo Nimrichter , Kildare Miranda, Susana Frases, Kym F. Faull, Arturo Casadevall, Marcio L. Rodrigues. Cryptococcus neoformans cryoultramicrotomy and vesicle fractionation reveals an intimate association between membrane lipids and glucuronoxylomannan. Fungal Genetics and Biology 46: 956–963, 2009. PMID: 19747978. [305] Durazo, Armando, Bryan F. Shaw, Madhuri Chattopadhyay, Kym F. Faull, Aram M. Nersissian, Joan Selverstone Valentine, and Julian P. Whitelegge. Metal-free superoxide dismutase-1 and three different ALS variants share a similar partially unfolded (-barrel at physiological temperature. Journal of Biological Chemistry. 284:34382-9, 2009. PMID: 19805550. [301] Budzik, Jonathan M., Catherine B. Poor, Kym F. Faull, Julian P. Whitelegge, Chuan He

and Olaf Schneewind

. Sequential synthesis of

amide bonds enables pilus formation on the surface of bacilli. Proc. Natl. Acad Sci (USA). 106:19992-7, 2009. PMID:19903875. Erratum in: Proc Natl Acad Sci U S A. 107: 5260. PMID:19903875. [303] Wolf, Mike C., Alexander N. Freiberg, Tinghu Zhang, Zeynep Akyol-Ataman, Andrew Grock, Patrick W. Hong, Jianrong Li, Natalya F. Watson, Angela Q. Fang, Hector C. Aguilar, Matteo Porotto, Anna N. Honko, Robert Damoiseaux, John P. Miller, Sara E. Woodson, Steven Chantasirivisal, Vanessa Fontanes, Oscar Negrete, Paul Krogstad, Asim Dasgupta, Anne Moscona, Lisa E. Hensley, Sean P. Whelan, Kym F. Faull, Michael R. Holbrook, Michael E. Jung and Benhur Lee. A broad-spectrum antiviral targeting entry of enveloped viruses. Proc. Natl. Acad Sci (USA). 107:3157-62, 2010. PMID: 20133606. [310] Tsirulnikov, Kirill, Natalia Abuladze, Myong-Chul Koag, Debra Newman, Karoline Scholz, Galyna Bondar, Quansheng Zhu, Nuraly K. Avliyakulov, Wolfgang Dekant, Kym Faull, Ira Kurtz, Alexander Pushkin. Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2). Toxicology and Applied Pharmacology. 244:218-25, 2010. PMID: 20060011. [300] Ryan, Christopher M., Puneet Souda, Sara Bassilian, Rachna Ujwal, Jun Zhang, Jeff Abramson, Peipei Ping, Armando Durazo, James Bowie, Saif Hasan, Danas Baniulis, William A. Cramer, Kym F. Faull, Julian P. Whitelegge. Post-translational modifications of integral membrane proteins resolved by top-down Fourier-transform mass spectrometry with collisionally activated dissociation. Molecular and Cellular Proteomics. 9:791-803, 2010. PMID: 20093275. [309] Shoemaker LD, Orozco NM, Geschwind DH, Whitelegge JP, Faull KF, Kornblum HI. Identification of differentially expressed proteins in murine embryonic and postnatal cortical neural progenitors. PLoS ONE, 5:e9121, 2010. PMID: 20161753. [280] Lu, Ming, Julian P. Whitelegge, Stephen A.Whelan, Jianbo He, Romaine E. Saxton, Kym F. Faull, Helena R. Chang. Hydrophobic Fractionation Enhances Novel Protein Detection by Mass Spectrometry in Triple Negative Breast Cancer. J Proteomics Bioinform.3:1-10, 2010. PMID: 20596302. [316] Ryan, Christopher M., Puneet Souda, Frédéric Halgand, David T. Wong, Joseph A. Loo, Kym F. Faull, Julian P. Whitelegge. Confident assignment of intact mass tags to human salivary Cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry. Journal of the American Society for Mass Spectrometry. 21:908-17, 2010. PMID: 20189825. [308]

Kym Francis FAULL

�PAGE �14�

Ryan, Christopher M., Puneet Souda, Sara Bassilian, Rachna Ujwal, Jun Zhang, Jeff Abramson, Peipei Ping, Armando Durazo, James U. Bowie, S. Saif Hasan, Danas Baniulis, William A. Cramer, Kym F. Faull and Julian P. Whitelegge. Post-translational Modifications of Integral Membrane Proteins Resolved by Top-down Fourier Transform Mass Spectrometry with Collisionally Activated Dissociation. Molecular and Cellular Proteomics. 9:791-803, 2010. PMID: 20093275. [304] Jansen,

Michael A., Jacqueline Kiwata, Jennifer Arceo, Kym F. Faull, Grady Hanrahan, and Edith Porter

. Evolving Neural Network

Optimization of Cholesteryl Ester Analysis by Reverse-Phase HPLC. Analytical and Bioanalytical Chemistry. 397:2367-74, 2010. PMID: 20490467. [307] Thangaraj, Balakumar, Christopher M. Ryan, Puneet Souda, Kirsten Krause, Kym F. Faull, Andreas Weber, Petra Fromme, Julian P. Whitelegge. Data-directed top-down Fourier-transform mass spectrometry of a large integral membrane protein complex, Photosystem II from Galdieria sulphuraria. Proteomics. 10:3644-56, 2010. PMID: 20845333. [320] Kern, Justin W., Christopher Ryan, Kym Faull, and Olaf Schneewind

. Bacillus anthracis surface-layer proteins assemble by binding to

the secondary cell wall polysaccharide in a manner that requires csaB and tagO. Journal of Molecular Biology. 401:757-75, 2010. PMID: 20603129. [321] Halgand, Frédéric, Vlad Zabrouskov, Sara Bassilian, Puneet Souda, David T. Wong,

Joseph A. Loo, Kym F. Faull, Julian P.

Whitelegge. Micro-heterogeneity of human saliva Peptide P-C characterized by high-resolution top-down Fourier-transform mass spectrometry. J Am Soc Mass Spectrom 21:868-877, 2010. PMID: 20185333. [296] Keire, David A., Julian P. Whitelegge, Puneet Souda, Sara Bassilian, Alvin C. Haver, Kym F. Faull, Roger D. Reidelberger, and Joseph R. Reeve Jr.

PYY(1-36) is the major form of PYY in rat distal small intestine: quantification using high-resolution mass

spectrometry. Regulatory Peptides. 165:151-7, 2010. PMID: 20615437. [302] Wang, Dorothy, Veena, S. Mysore, Stevenson, Kerry, Tang, Christopher, Ho, Baran, Suh, Jeffrey D., Duarte, Victor M., Eugene Han, Mysore S. Veena, Amanda Salvado, Jeffrey D. Suh, Li-Jung Liang, Kym F. Faull, Eri S. Srivatsan, and Marilene B. Wang. Curcumin e h es the effe t f isp ti i the suppressi f he d d e squ us e r i vi the i hibiti f IKKβ pr tein of the u e r f t r B (NFκB) p thw y. Molecular Cancer Therapeutics. 9(10):2665-75, 2010. PMID. 20937593. [313] Kongmanas, Kessiri, Hongbin Xu, Arman Yaghoubian, Laura Franchini, Luigi Panza, Fiamma Ronchetti, Kym Faull, Nongnuj Tanphaichitr. Seminolipid quantification by colorimetric assay and ESI-LC-MS/MS-multiple reaction monitoring: compensation of seminolipid expression in Cgt+/- mice. Journal of Lipid Research. 51:3548-58, 2010. PMID: 20817833. [317] Leuchter, Andrew F., Ian A. Cook, Steven P. Hamilton, Katherine L. Narr, Arthur Toga, Aimee M. Hunter, Kym Faull, Julian P. Whitelegge, Anne M. Andrews, Joseph Loo, Baldwin Way, Stanley F. Nelson, Steven Horvath AND Barry D. Lebowitz. Biomarkers to Predict Antidepressant Response. Current Psychiatry Reports 12:553–562, 2010. PMID: 20963521. [323] Barnard H., A.N. Dooley, G. Areshian, B. Gasparyan and K.F. Faull. Chemical evidence for wine production around 4000 BCE in the Late Chalcolithic Near Eastern highlands, Journal of Archaeological Science 38: 977-984, 2011. doi:10.1016/j.jas.2010.11.012 [325] Webb, Kristofor J., Cecilia Zurita-Lopez, Qais Al-Hadid, Arthur Laganowsky, Brian D. Young, Rebecca S. Lipson, Puneet Souda, Kym F. Faull, Julian P. Whitelegge and Steven G. Clarke. A Novel 3-Methylhistidine Modification of Yeast Ribosomal Protein Rpl3 is Dependent upon the YIL110W Methyltransferase. Journal of Biological Chemistry 285:37598-37606, 2010. PMID: 20864530. [322] Thuc Le,

Kee-Pyo Kim, Guoping Fan

and Kym F. Faull

. A sensitive mass-spectrometry method for simultaneous quantification of

5hmC and 5mC levels in biological samples. Analytical Biochemistry. 412:203-9, 2011. PMID: 21272560. [328] Meytal Landau, Meytal, Michael R. Sawaya, Kym F. Faull, Arthur Laganowsky, Lin Jiang, Stuart Sievers1, Jie Liu3, Jorge Barrio and David Eisenberg. The amyloid pharmacophore. PLoS Biol. 9:e1001080, 2011. PMID: 21695112. [324] He, Jianbo, Stephen A. Whelan, Ming Lu, Dejun Shen, Debra U. Chung, Romaine E. Saxton, Kym F. Faull, Julian P. Whitelegge and Helena R. Chang. Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response. International Journal of Proteomics, 2011 2011:896476.. PMID: 22110952 [318] Lam, Maggie P.Y., Sarah B. Scruggs, Tae-Young Kim, Chenggong Zong, Edward Lau, Ding Wang, Christopher M. Ryan, Kym F. Faull, Peipei Ping

. An MRM-based Workflow for Quantifying Cardiac Mitochondrial Protein Phosphorylation in Murine and Human

Tissue. Journal of Proteomics. 75: 4602-9, 2012. PMID: 22387130. [333]

Kym Francis FAULL

�PAGE �15�

Halgand FJ, Zabrouskov V, Bassilian S, Souda P, Loo JA, Faull KF, Wong DT, Whitelegge JP. Defining intact protein primary structures from saliva: a step toward the human proteome project. Analytical Chemistry. 84: 4383-95, 2012. PMID: 22509742. [336]. Babiec

, Walter E., Kym F. Faull, Jack L. Feldman

. Cyclothiazide-induced persistent increase in respiratory-related activity in vitro.

Journal of Physiology. 590: 4897-915, 2012. PMID: 22753547. [331] Tsirulnikov, Kirill, Abuladze, N., Bragin, A., Faull, K., Cascio, D., Damoiseaux, R., Schibler, M., Pushkin, A. Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicology and Applied Pharmacology. 263: 303-14, 2012. PMID: 22819785. [334] Tsirulnikov, K., Abuladze, N., Vahi, R., Hasnain, H., Phillips, M., Ryan, C.M., Atanasov, I., Faull, K.F., Kurtz, I., Pushkin, A., Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein, FEBS Letters. 586: 3799-804, 2012. PMID: 23010594. [342] Dawlaty, Meelad, Achim Breiling, Thuc Le, Guntur Raddatz, M. Inmaculada Barrasa, Albert Cheng, Qing Gao, Benjamin Powell, Zhe Li, Mingjiang Xu, Kym F. Faull, Frank Lyko, and Rudolf Jaenisch

. Combined deficiency of Tet1 and Tet2 causes epigenetic

abnormalities but is compatible with postnatal development. Developmental Cell, 24: 1–14, 2013. PMID: 23352810. [344] Vincent, John J, Yun Huang, Pao-Yang Chen, Suhua Feng, Joseph H Calvopina, Kevin Nee, Serena A. Lee, Thuc Le, Alexander J. Yoon, Kym Faull, Guoping Fan, Anjana Rao, Steven E Jacobsen, Matteo Pellegrini, Amander T Clark. Stage-specific roles for Tet1 and Tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell, 12: 470-8, 2013. PMID: 23415914. [345] Sarafian, Theodore A., Christopher M. Ryan, Puneet Souda, Upendra K. Kar, Kym F. Faull, Julian P. Whitelegge, Joseph B. Watson. Impairment of mitochondria in adult mouse brain overexpressing N-ter i y ety ted hu α-synuclein. PloS1, 8: e63557. PMID: 23667637. [335] Li, Sichen, Arthur P. Chou, Weidong Chen, Ruihuan Chen, Alan Deng, Heidi S. Phillips, Kym F. Faull, Jeff M. Bronstein, Timothy Cloughesy, Linda M. Liau, and Albert Lai

.. Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more

sensitive to radiation. Neuro Oncol, 15: 57-68, 2013. PMID: 23115158. [329] Xu, Hongbin, Kessiri Kongmanas, Suraj Kadunganattil, Charles E. Smith, Tony Rupar, Naoko Goto-Inoue, Louis Hermo, Kym F. Faull, and Nongnuj Tanphaichitr. Arylsulfatase A deficiency causes seminolipid accumulation and a lysosomal storage disorder in Sertoli cells. J. Lipid Research, 52: 2187-97, 2011. PMID: 21965315. [330] Lam MP, Lau E, Scruggs SB, Wang D, Kim TY, Liem DA, Zhang J, Ryan CM, Faull KF, Ping P. Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation. J Proteomics. 81:15-23. 2013. PMID: 23022582. [339] Rudenko, Andrii, Meelad M. Dawlaty, Jinsoo Seo, Albert W. Cheng, Jia Meng, Thuc Le, Kym F. Faull, Rudolf Jaenisch and Li-Huei

Tsai. Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction. Neuron, 18: 1109-22, 2013. PMID:

24050401. [352] Janzen, Deanna M., Daniel Y. Paik, Miguel A. Rosales, Brian Yep, Donghui Cheng, Owen N.Witte, Huseyin Kayadibi, Christopher M. Ryan, Michael E. Jung, Kym Faull, and Sanaz Memarzadez. Low levels of circulating estrogen sensitize PTEN-null endometrial tumors to poly(ADP-ribose) polymerase (PARP) inhibition in vivo. Molecular Cancer Therapeutics, 12: 2917-28, 2013. PMID: 24222661. [346] Thomer, Lena, Samuel Becker, Carla Emolo, Austin Quach, Hwan Keun Kim, Sabine Rauch, Mark Anderson, James F. LeBlanc, Olaf Schneewind, Kym F. Faull, Dominique Missiakas. N-acetylglucosaminylation of serine-aspartate repeat proteins promotes Staphylococcus aureus blood stream infection. Journal of Biological Chemistry, 289: 3478-86, 2014. PMID: 24344128. [355] Nathanson, David A.,Amanda L. Armijo, Michelle Tom, Zheng Li, Wayne R. Austin,

Julian Nomme, Dean O. Campbell,

Elizabeth

Dimitrova, Lisa Ta, Thuc Le, Jason T. Lee,

Ryan Darvish, Ari Gordin,

Liu Wei, Hsiang-I Liao, Moses Wilks, Colette Martin, Saman

Sadeghi, Jennifer M. Murphy, Nidal Boulos, Michael E. Phelps, Kym F. Faull, Harvey R. Herschman, Michael E. Jung, Johannes Czernin, Arnon Lavie, and Caius G. Radu. Co-Targeting of Convergent, Switchable Nucleotide Biosynthetic Pathways Induces Synthetic Lethality in Leukemia. Journal of Experimental Medicine, 2014 Feb 24. [Epub ahead of print]. PMID: 24567448. [349] Cole, Stephanie J., Alexander J. Yoon, Kym F. Faull, Andrew C. Diener. Host perception of jasmonates promotes infection by Fusarium oxysporum formae speciales that produce isoleucine- and leucine-conjugated jasmonates. Molecular Plant Pathology. 2014 Jan 6. [Epub ahead of print]. PMID: 24387225. [337]

Kym Francis FAULL

�PAGE �16�

w ty ee d . A hi Brei i g Thu e . I u d B rr s nter Raddatz, Qing Gao, Benjamin E. Powell1, Albert W. Cheng, Kym F. Faull, Frank Lyko, and Rudolf Jaenisch. Loss of Tet enzymes compromises normal differentiation of embryonic stem cells. Developmental Cell, in press. [356] Sun, D., M. Luo, M. Jeong, B. Rodriguez, Z. Xia, R. Hanna, H. Wang, T. Le, K. Faull, R. Chen, H. Gu, C. Bock, A. Meissner, B. Gottgens, G. Darlington, W. Li, and M.A. Goodell. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell, In Press, 2014. [351] Randall C., Xudong Fu, Melody Pai, Laurent Vergnes, Simon Diep, Brett Lomenick, Gang Deng, Vijaykumar Meli, Gabriela C. Monsalve, Heejun Hwang, Eileen Hu, Gwanghyun Jung, Stephen A. Whelan, Farbod Fazlollahi, Chitrada Kaweeteerawat

8, Hilary A.

Godwin, Helena R. Chang, Kym F. Faull, Meisheng Jiang, Catherine F. Clarke, Michael Petrascheck, Karen Reue, Michael E. Jung, Alison R. Frand, and Jing Huang. Alpha-ketoglutarate extends lifespan in Caenorhabditis elegans by a novel mechanism mediated by the ATP synthase and TOR. Nature, in press. [350] Bullwinkle, Tammy, Noah Reynolds, Medha Raina, Adil Moghal, Eleftheria Matsa, Andrei Rajkovic, Huseyin Kayadibi, Farbod Fazlollahi, Christopher Ryan, Nathaniel Howitz, Kym Faull, Beth Lazazzera

and Michael Ibba. Oxidation of cellular amino acid pools

leads to context-dependent cytotoxic mistranslation of the genetic code. eLife, in press. [347] Clark, Peter M., Graciela Flores, Nikolai M. Evdokimov, Melissa N. McCracken, Timothy Chai, Evan Nair- i Fi O’ h y Simon W. Beaven, Kym F. Faull Michael E. Phelps, Michael E. Jung, Owen N. Witte.A novel positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. Proc. Natl, Acad. Sci. In press. [353] Kongmanas, Kessiri, Hathairat Kruevaisayawan, Arpornrad Saewu, Clarissa Sugeng, Jason Fernandes, Puneet Souda, Jonathan Angel, Kym F. Faull, R. John Aitken, Julian Whitelegge, Dan Hardy, Trish Berger, Mark Baker, Nongnuj Tanphaichitr. Proteomic Characterization of Pig Sperm Anterior Head Plasma Membrane Vesicles Reveals Roles of Acrosomal Proteins in ZP3 Binding. Journal of Cellular Physiology, 230: 449–463, 2015. [361] Huang, Kevin, Zhourui Wu, Zhenshan Liu, Ganlu Hu, Juehua Yu, Kai H. Chang, Kee-Pyo Kim, Thuc Le, Kym F. Faull, Nagesh Rao, Andrew Gennery, Zhigang Xue, Cun-yu Wang, Matteo Pellegrini, Guoping Fan. Selective demethylation and altered gene expression are associated with ICF Syndrome in human induced pluripotent stem cells and mesenchymal stem cells. Human Molecular Genetics. In press. [360] Calkins, Kara L., Lauren A. Sanchez, Chi-Hong Tseng, Kym F. Faull, Alexander J. Yoon, Christopher M. Ryan, Thuc Le, Stephen B. Shew. High-Dose Cysteine Supplementation and Erythrocyte Glutathione Concentrations: a Double-Blinded, Randomized Controlled in Critically Ill Neonates. Journal of Parenteral and Enteral Nutrition, in press. DOI: 10.1177/0148607114546375. [354] Fazlollahi F, Kongmanas K, Tanphaichitr N, Clair JM, Gopen Q, Faull KF, Suh JD. Lipidomic Profiling of Sinus Mucosa from Patients with Chronic Rhinosinusitis. Clin Transl Sci. 2015 Jan 15. doi: 10.1111/cts.12256. [Epub ahead of print]. [358] Fazlollahi, Farbod, Kessiri Kongmanas, Nongnuj Tanphaichitr, Jeffrey Suh, Kym Faull, Quinton Gopen. Lipidomic Profiling of Mastoid Bone and Tissue from Patients with Chronic Otomastoiditis. International Archives of Otorhinolaryngology. In press. [359] Jian Feng, Ningyi Shao, Keith E. Szulwach, Vincent Vialou, Jimmy Huynh, Chun Zhong, Thuc Le, Deveroux Ferguson, Michael E. Cahill, Yujing Li, JaWook Koo, Efrain Ribeiro, Benoit Labonte, Benjamin M. Laitman, David Estey, Victoria Stockman, Pamela Kennedy, Thomas Couroussé, Isaac Mensah, Gustavo Turecki, Kym F. Faull, Guo-li Ming, Hongjun Song, Guoping Fan, Patrizia Casaccia, Li Shen, Peng Jin, and Eric J. Nestler. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature Neuroscience. In press. [370] Tanphaichitr N, Kongmanas K, Kruevaisayawan K, Saewu A, Sugeng C, Fernandes J, Souda P, Angel JB, Faull KF, Aitken RJ, Whitelegge J, Hardy D, Berger T and Baker M. Remodelling of the plasma membrane in preparation for sperm-egg recognition: Roles of acrosomal membranes. Asian Journal of Andrology (a special issue for the proceedings of the 12

th International Symposium of

Spermatology). In press. [371] Ma, Daniel, Alexander Yoon, Kym F. Faull, Robert Desharnais, Edith T. Zemanick and Edith Porter. Antimicrobial cholesteryl esters are elevated in bronchial lavage fluid collected from pediatric cystic fibrosis patients and may serve as novel biomarker for disease. PLOS ONE. In press. [363] Tanphaichitr, Nongnuj, Kessiri Kongmanas, Hathairat Kruevaisayawan, Arpornrad Saewu, Clarissa Sugeng, Jason Fernandes, Puneet Souda, Jonathan B Angel, Kym F Faull, R John Aitken, Julian Whitelegge, Daniel Hardy, Trish Berger, Mark Baker. Remodeling of the plasma membrane in preparation for sperm–egg recognition: roles of acrosomal proteins. Asian Journal of Andrology, invited research highlight, 17, 574–582; doi: 10.4103/1008-682X.152817; published online: 18 May 2015 [375]

Kym Francis FAULL

�PAGE �17�

Chattopadhyay, Arnab, Victor Grijalva, Greg Hough, Feng Su, Pallavi Mukherjee, Robin Farias-Eisner, G.M. Anantharamahiah, Kym F. Faull, Lin H. Hwang, Mohamad Navab, Alan M. Fogelman, and Srinivasa T. Reddy. Efficacy of Tomato Concentrates in Mouse Models of Dyslipidemia and Cancer. Pharmacology Research & Perspectives., 3(4), 2015, e00154, doi: 10.1002/prp2.154 [368]

Sen, Suvajiy, Kawahara, Brian. Divya Gupta, Rebecca Tsai, Sinchita Roy Chowdhuri, Shikha Bose, Marine Khachatryan, Alexander Yoon, Kym Faull, Robin Farias-Eisner, Gautam Chaudhuri. Role of Cystathionine β-Synthase in Human Breast Cancer. Free Radical Biology & Medicine. In press [336]

Rajkovic, Andrei, Sarah Tyler, Annie Kalinoski, Owen E Branson, Jin Seo, Philip R. Gafken, Michael Frietas, Julian Whittelegge, Kym Faull, William Navarre, Andrew Darwin

5and Michael Ibba. Cyclic rhamnosylated EF-P establishes antibiotic resistance in

Pseudomonas PAK. mBio. In press [374]

Lesage, Denis, Gabriella Barozzino-Consiglio, Romain Duwald,

Catherine Fressigné,

Anne Harrison-Marchand,

Kym F. Faull,

Jacques

Maddaluno, and Yves Gimbert. A Lithium Amide Protected Against Protonation in the Gas Phase: Unexpected Effect of LiCl. J.

Organic Chemistry. In press [378].

Xudong Fu, Xudong, Randall M. Chin, Laurent Vergnes, Heejun Hwang, Gang Deng, Yanpeng Xing, Melody Y. Pai2, Sichen Li, Lisa Ta1, Farbod Fazlollahi, Chuo Chen, Robert M. Prins, Michael A. Teitell, David A. Nathanson, Albert Lai, Kym F. Faull, Meisheng Jiang, Steven G. Clarke, Timothy F. Cloughesy, Thomas Graeber, Daniel Braas, Heather R. Christofk, Michael E. Jung, Karen Reue, Jing Huang. 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. Cell Metabolism. In press. [379]

Evdokimov, Nicolai, M., Peter M. Clark, Graciela Flores, Timothy Chai, Kym F. Faull, Michael E. Phelps, Owen N. Witte, and Michael E. Jung. Development of 2‑ Deoxy-2‑ [18F]fluororibose for Positron Emission Tomography Imaging Liver Function in Vivo. Journal of Medicinal Chemistry. In press. [364]

Porter, Edith, Daniel C Ma, Sandy Alvarez, and Kym F Faull. Invited manuscript: Antimicrobial Lipids: Emerging Effector Molecules of Innate Host Defense. World Journal of Immunology, 5:51-61. Published online 2015 July 27. doi: 10.5411/wji.v5.i2.51. [377]

Kym Francis FAULL

�PAGE �18�

BIBLIOGRAPHY CONTINUED PUBLICATIONS Book Chapters, Reviews and Technical Reports, published or in press Faull, K.F., Gan, I., Halpern, B. and Danks, D.M. The use of stable isotopes for the in vivo study of metabolic disorders. Proceedings of the Second International Conference on Stable Isotopes. E. R. Klein and P. D. Klien, eds., U.S.E.R.D.A. Conf. 751027, pp. 392-399, 1975. [39] Faull, K.F., Foutz, A.S., Holman, R.B., Anderson, P.J. and Dement, W.C. Assays of monoamine metabolites in CSF samples from control and narcoleptic canines. In: Catecholamines: Basic and Clinical Frontiers, Vol. 2. E. Usdin, I. Kopin and J.D. Barchas, eds., New York/London: Pergamon Press, pp. 1602-1604, 1979. [40] Berger, P.A., Faull, K.F., Davis, K.L. and Barchas J.D. Monoamine metabolites in CSF in psychiatric disorders. In: Catecholamines: Basic and Clinical Frontiers, Vol. 2. E. Usdin, I. Kopin and J.D. Barchas, eds., New York/London: Pergamon Press, pp. 1827-1829, 1979. [41] Davis, K.L., Faull, K.F., Hollister, L.E., Berger, P.A. Physostigmine induced alterations of dopamine metabolites in CSF of normal subjects. In: Catecholamines: Basic and Clinical Frontiers, Vol. 2. E. Usdin, I. Kopin and J.D. Barchas, eds., New York/London: Pergamon Press, pp. 1122-1124, 1979. [48] Holman, R.B., Eger, G., Anderson, P.J. and Faull, K.F. In vivo release of neurotransmitters monitored by continuous cerebral ventricular perfusion in the rat: Effects of alcohol. In: Catecholamines: Basic and Clinical Frontiers, Vol. 2. E. Usdin, I. Kopin and J.D. Barchas, eds., New York/London: Pergamon Press, pp. 1798-1800, 1979. [49] Davis, K.L., Faull, K.F., Hollister, L.E., Barchas, J.D. and Berger, P.A. Physostigmine-related changes in cerebral spinal fluid neurotransmitter metabolites in man. In: Brain Acetylcholine and Neuropsychiatric Disease. K.L. Davis and P.A. Berger, eds., New York: Plenum Press, pp. 435-443, l979. [50] Holman, R.B., Elliott, G.R., Faull, K. and Barchas, J.D. Tryptolines: the role of indoleamine-aldehyde condensation products in the effects of alcohol. In: Psychopharmacology of Alcohol. M. Sandler, ed., pp. 155-169, New York: Raven Press, 1980. [51] Faull, K.F., Holman, R.B., Elliott, G.R. and Barchas, J.D. Tryptolines: artifact or reality. A new method of analysis using GC/MS. In: Beta-Carbolines and Tetrahydroisoquinolines. E. Usdin, F. Bloom and J.D. Barchas, eds., New York: Allan R. Liss, Inc., pp. 135-154, 1982. [52] Guilleminault, C. and Faull, K.F. Sleepiness in non-narcoleptic, non-sleep apneic EDS patients: The idiopathic CNS hypersomnolence. Sleep 5:S175-S181, 1982. [56] Faull, K.F. and Barchas, J.D. Negative-ion mass spectrometry fused- silica capillary gas chromatorgraphy of neurotransmitters and related compounds. In: Methods of Biochemical Analysis, D. Glick, ed. New York: John Wiley & Sons, Inc., Vol. 29, pp. 325-383, 1983. [57] Faull, K.F., Barchas, J.D., Kenyon, C.N. and Goodley, P.C. Particle induced desorption mass spectrometry with a quadrupole GC/MS instrument. (Presented at the Ninth International Mass Spectrometry Meeting, Vienna, 1982.) Int J Mass Spectrom Ion Physics, 46:347-350, 1983. [58] Mahoney, J.F., Perel, J., Goodley, P.C., Kenyon, C.N. and Faull, K. Modification of an HP 5985B GC/MS for FAB using a fast atom capillaritron source (FACS). (Presented at the Ninth International Mass Spectrometry Meeting, Vienna, 1982.) Int J Mass Spectrom Ion Physics, 48:419-422, 1983. [59] Kenyon, C.N., Goodley, P.C., Dixon, D.J., Whitney, J.O., Faull, K.F. and Barchas, J.D. Direct liquid inlet-LC/MS and negative chemical ionization MS. American Laboratory, 15:38-49, 1983. [60] Faull, K. F. and Barchas, J. D. Analysis of catecholamines and their metabolites by combined gas chromatography-mass spectrometry. In: Methods in Biogenic Amine Research. S. Parvez, T. Nagatsu, I. Nagatsu and H. Parvez, eds., Amsterdam/New York: Elsevier/North Holland Medical Press, pp. 189-236, 1983. [61] Faull, K.F., King, R.J., Berger, P.A. and Barchas, J.D. Systems theory as a tool for integrating functional interactions among biogenic amines. In: Catecholamines Part C: Neuropharmacology and Central Nervous System - Therapeutic Aspects. E. Usdin, A. Carlsson, A. Dahlstrom and J. Engel, eds., New York: Alan R. Liss, Inc., pp. 143-152, 1984. [62]

Kym Francis FAULL

�PAGE �19�

Faull, K.F., Kraemer, H.C., Barchas, J.D. and Berger, P.A. CSF probenecid and biogenic amines. Biological Psychiatry, 19:1357-1358 (Letter to the Editor), 1984. [63] Perel, J., Faull, K., Mahoney, J.F., Tyler, A.N. and Barchas, J.D. Direct insertion probe gun for FAB mass spectrometry. American Laboratory, November 1984. [64] Beck, O., Faull, K.F., Barchas, J.D., Johnson, J.V. and Yost, R.A. Chiral analysis of urinary 5-hydroxymethtryptoline: Implications for endogenous biosynthesis and formation during ethanol intoxication. In: Aldehyde Adducts in Alcoholism. M.A. Collins, ed., New York: Alan R. Liss, Inc., pp. 145-160, 1985. [65] Johnson, J.V., Yost, R.A., Beck, O., and Faull, K.F. The use of tandem mass spectrometry for the identification and quantitation of tryptolines (tetrahydro-ß-carbolines) in tissue extracts. In: Aldehyde Adducts in Alcoholism. M.A. Collins, ed., New York: Alan R. Liss, Inc., pp. 161-177, 1985. [66] Faull, K.F., King, R. and Barchas, J.D. The solubility of lithium salts on organic solvents. Biol Psych 20:461 (Letter to the Editor), 1985. [67] Johnson J.V., Yost, R.A., Faull, K.F. and Beck, O. GC/MS/MS for the simultaneous determination of indoleamines and tryptolines in crude extracts of rat brain. Advances in Mass Spectrometry 10:1463-1464, 1985 (Proceedings of the Tenth International Mass Spectrometry Conference, Swansea, Wales, United Kingdom). [70] Beck, O., Greene K.A. and Faull K.F. Convenient extraction and mass spectrometric assay of 3-methoxytyramine, normetanephrine and metanephrine in biological fluids. Advances in Mass Spectrometry 10:1297-1298, 1985 (Proceedings of the Tenth International Mass Spectrometry Conference, Swansea, Wales, United Kingdom). [74] Spiker, D.G., Berger, P.A., Dealy, R.S., Faull, K.F., Griffen, S.J., Jarrett, D.B. and Kupfer, D.J. The psychobiology of delusional depression: a preliminary report. In: Biological Psychiatry 1985 (Proceedings of the IVth World Congress of Biological Psychiatry, Philadelphia, September 1985), C. Shagass, R.C. Josiassen, W.H. Bridger, K.J. Weiss, D. Stoff, G.M. Simpson eds. New York: Elsevier, pp 717-719 1986. [75] Faull, K.F., Feistner, G., Greene, K.A. and Beck, O. Advances in mass spectrometry: new horizons for neurosciences. In: Trends in Neuroscience, 9:102-107, 1986. [68] Faull, K.F. and Beck, O. Quantification of neurotransmitters and related compounds by electron capture chemical ionisation GC-MS. In: Mass Spectrometry in Biomedical Research, Simon Gaskell, ed. Chichester: John Wiley & Sons, pp. 403-421 (Chapter 22), 1986. [69] Barchas, J.D., Tatemoto, K., Faull, K.F., Evans, C.J., Valentino, K.L. and Eberwine, J.H. The search for neuropeptides. In: Psychopharmacology: A Third Generation of Progress, H.Y. Meltzer, ed. New York: Raven Press, pp. 437-447, 1987. [71] Beck, O., Tyler, A. and Faull, K. Serotonin condensation product 5-hydroxymethtryptoline: Evidence for in vivo formation from acetaldehyde during intoxication using deuterium labelled ethanol (Proceedings of the Third ISBRA Congress). Alcohol & Alcoholism, Suppl. 1, pp. 743-747, 1987. [72] Faull, K.F. Application of combined gas chromatography/mass spectrometry to neurotransmitter research. Life Sciences, 41:889-892, 1987. [73] Csernansky, J.G., Faull, K.F. and Pfefferbaum, A. Letter to the Editor: Seasonal changes in CSF monoamine metabolites in psychiatric patients; what is the source? Psychiatry Research, 25:361-363, 1988. [101] Sharma, R., Javaid, J.I., Janicak, P., Comaty, J., Davis, J.M. and Faull, K. Letter to the Editor: The effect of trifluoroperazine on CSF and plasma HVA in schizophrenic subjects. Am J Psychiatry, 145: 1480-1481 (1988). [103] Barchas, J.D., Faull, K.F. and Elliot, G.R. Biochemical aspects of the psychotic disorders. In: Basic Neurochemistry: Molecular,

Cellular and Medical Aspects. 4th Edition, edited by G.J. Siegel, B.W. Agranoff, R.W. Albers, and P.B. Molinoff, Raven Press Ltd., New York 1989, chapter 45, pp 859-875. [76] Faull, K.F., Pascoe, N. and Goodley, P. Construction and use of a simple and inexpensive GC-MS transfer line for changing fused silica GC columns "on the fly". LC-GC Magazine, 7: 144-148 (1989), and also published in LC-GC International, 2: 56-58 (1989). [105]

Kym Francis FAULL

�PAGE �20�

Feistner, G.J., Faull, K.F., Evans, C.J., Roepstorff, P., Horup, P. andBarofsky, D.F. PD-MS and FAB-MS for the charting of neuropeptides. In Advances in mass spectrometry, edited by P. Longevialle, Heydon and Sons, 11:1380-1381, 1989. [Procedings of the 11th International Mass Spectrometry Conference, Bordeaux, France, 1988] [127] Csernansky, J.G., Poscher, M. and Faull, K.F. Serotonin in schizophrenia. In: Serotonin in Major Psychiatric Disorders, ed. E.F. Coccaro and D.L. Murphy (APA press, Inc.: Progress in Psychiatry Monograph Series: series editor David Spiegel), pp 211-230, 1990. [93] Barofsky, D.F., Feistner, G.J., Faull, K.F. and Roepstorff, P. Peptide charting applied to studies of precursor processing in endocrine tissues. In: Mass Spectrometry of Peptides, Chapter 18, pp 347-365, edited by D. M. Desiderio, CRC press, Boca Raton, Florida, 1990. [114] Benson, K.L., Csernansky, J.G., Faull, K.F., and Zarcone, V.P. Alprazolam: effect on depression, sleep and CSF neurotransmitter metabolites. A technical report to the Upjohn Company, March 20, 1990. [126] Feistner, G.J., Barofsky, D.F., Evans, C.J., Faull, K.F., and Roepstorff, P. Charting of rat pituitary peptides by plasma desorption and electrospray ionization mass spectrometry. In: "Methods and Mechanisms for Producing Ions from Large Molecules", pp 45-52, edited by K. Standing and W. Ens, Plenum Press, NY, 1991. Procedings of a NATO Advanced Research Workshop held at Lake Minaki, 24-28 June 1990. NATO ASI Science Series. [125] Faull, K.F. Neurotransmitters. In "Mass spectrometry: clinical and biomedical applications", edited by Dominic Desiderio, Plenum Press, pp 167-205, 1992 [128] Faull, K.F. Mammalian morphine alkaloids: identification and possible in vivo biosynthesis. In "The Biological Basis of Substance Abuse and its Therapy", edited by Stanley G. Korenman and Jack D. Barchas, Oxford University Press, pp 267-283, 1993. [129] Faustman, W.O., Elliott, P.J., Ringo, D.L. and Faull, K.F. Letter to the Editor: CSF 5-HIAA and atmospheric pressure; a failure to replicate. Biological Psychiatry 33:58-59, 1993. PMID: 7678378. [140] Barchas, J.D., Faull, K.F., Quin, B. and Elliot, G.R. Biochemical aspects of the psychotic disorders. In: Basic Neurochemistry:

Molecular, Cellular and Medical Aspects. 5th Edition, edited by G.J. Siegel, B.W. Agranoff, R.W. Albers, and P.B. Molinoff, Raven Press Ltd., New York., pp 959-977, 1993. [141] Orlino, E.N., Olmstead, C.E., Fluharty, A.L. and Faull, K.F. Indicators of brain damage in experimental hydrocephalus: neuroamine related compounds in the cerebrospinal fluid. Pacific State Archives 19:809-86, 1994. [178] Glasgow, B.J., Abduraginov, A.R., Yusifov, T.N., Faull, K.F. and Hubbell, W.L. Tear lipocalins bind a broad array of lipid ligands. Current Eye Research 14:363-372, 1995 PMID: 7648862. [116a, late entry] Fluharty, A.L. Faull, K.F., Stevens, R.L. and Waring, A.L. Structural studies on the cerebroside sulfate activator protein (SAP-1, Saposin B). (Abstr.) J. Neurochemistry: 64: suppl S10 , 1995. [164] Waring, A., Faull, K., Curtain, C., and Gordon, L. Conformational mapping of a fusion peptide by electrospray MS/MS, isotope-enhanced FTIR spectroscopy and ESR spin-labeling. In: Bulletin of Magnetic Resonance (Gorenstein, D. Edt) Quarterly Review Journal of the International Society for Magnetic Resonance 17: 238-239, 1995. [162] Glasgow, B.J., Abduraginov, A.R., Farahbakhsh, Z.T., Faull, K.F., Hubbell, W.L. and Horwitz, J. Characterization of the disulfide motif in the major isoform of tear lipocalin. Investigative Ophthalmology & Visual Science 37:3921, 1996 [53a] Faull, K.F., Whitelegge, J.P., Waring, A.J., Stevens, R.L., To, T., Fluharty, C.B., and Fluharty, A.L. Protease suseptibility of deglycosylated Cs activator protein (Saposin B) (Abstr.). J. Neurochemistry: 69 (suppl):S192D, (1997). Leitinger, N., Watson, A.D., Faull, K.F., Fogelman, A.M. and Berliner, J.A. Monocyte binding to endothelial cells induced by oxidized phospholipids present in minimally oxidised low density lipoprotein is inhibited by a platelet activating factor receptor antagonist. Advances in Experimental Medicine and Biology 433:379-382 (1997). PMID: 9561175. [168] Whitelegge, J.P., Faull, K.F., Penn, B., To, T., Waring, A.W., Fluharty, C. and Fluharty, A. Investigation of the effect of protein oxidation upon the lipid-binding activity of the cerebroside-sulffate activator protein (Saposin B). In "New methods for the study of molecular aggregates" NATO ASI Science Series, Kluwer, pp67-73, 1998. [166]

Kym Francis FAULL

�PAGE �21�

Tjon, K, Faull, Kym and Whitelegge, J. Report on the effects of formic acid on disulfide chemistry. UCLA Undergraduate Science Journal pp 132-136, 2000. [209] Patel, A. and Faull, K.F. Binding specificity of the of the cerebroside sulfate activator protein (CSAct). Pacific State Archives 24:79- 87, 2000. [210] Lee, R.H., Ng, P.S., Yu, H. and Faull, K. Phosducin is phosphorylated in vivo at multiple sites. Investigative Ophthalmology & Visual Science, 42:1008 Suppl. S, 2001. [229] Carroll, K. and Faull, K.F. Development of a method for measurement of CSAct oxoforms in human uriune Pacific State Archives 26:101-107, 2001. [176] Nitao,L.K., Szent-Gyorgyi, A.G., Whitelegge, J.P., Faull, K.F. and Reisler, E. Characterization of monofunctionally modified scallop S1. Biophysical Journal 82: 1975 Part 2, 2002. [230] Glasgow, B, J., Abduragimov, A.R., Gassymov, O.K., Faull, K.F., Yusifov, T.N., and Lehrer, R.I. Characterization of a lipophilin in rabbit tears. Advances in Experimental Medicine and Biology 506(Pt A): 573-80 (2002). PMID: 12613962. [215] Glasgow BJ, Abduragimov AR, Gassymov OK, Yusifov TN, Ruth EC, Faull KF. Vitamin E associated with the lipocalin fraction of human tears. Advances in Experimental Medicine and Biology 506(Pt A): 567-72 (2002). PMID: 12613961. [237] Sattin A., Pekary AE, Lloyd RL, Paulson M, Meyerhoff JA, Hinkle PM and Faull K. TRH and Related Peptides: Homeostatic Regulators of Glutamate Transmission? Ann N Y Acad Sci. 1003:458-460, 2003. PMID: 14684488. [240] Chang, Apryl, Norris, Andrew and Faull, Kym F. Detection ofgalactosylsphingosine in urine samples of Krabbe's patients using electrospray ionization nmass spectrometry. Pacific State Archives 29:25-31, 2004. [257] Faull, Kym F. Review of the book entitled "Mass Spectrometry in Biophysics: Conformation and Dynamics of Biomolecules" by Igor A. Kaltashov and Stephen J. Eyles (University of Massachusetts at Amherst). From the Wiley-Interscience Series in Mass Spectrometry. Edited by Dominic M. Desiderio and Nico M. M. Nibbering. John Wiley & Sons, Inc. Hoboken. 2005. xvi + 458 pp. $89.95. ISBN: 0-471-45602-0. Journal of the American Chemical Society. 127: 16339-16340, 2005. [259] Barnard H, Dooley AN, Faull KF. An Introduction to Archaeological Lipid Analysis by combined gas chromatography mass spectrometry GC/MS. In: H. Barnard and J.W. Eerkens (eds.). Theory and Practice of Archaeological Residue Analysis. British Archaeological Reports International Series. Oxford, Archaeopress, chapter 5, pp 42-60, 2007. [254]. Faull, Kym F., Alek N. Dooley, Frédéric Halgand, Lorelei D. Shoemaker, Andrew J. Norris, Christopher M. Ryan, Arthur Laganowsky, Jodie V. Johnson

and Jonathan E. Katz. Chapter 1: An introduction to the basic principles and concepts of mass

spectrometry. In "Protein Mass Spectrometry" edited by Julian Whitelegge, Ph.D. Elsevier BV, Amsterdam, The Netherlands. [285] Shaw, Bryan F., Demetri T. Moustakas, Julian P. Whitelegge, and Kym F. Faull. Taking charge of proteins: from neurodegeneration to industrial biotechnology. Advances in Protein Chemistry and Structural Biology. Alexander McPherson Editor, Volume 79, pp 128-158, 2010. Elsevier Press. [314] Nigra, Benjamin T., Kym F. Faull and Hans Barnard. Analytical Chemistry in Archaeological Research. Analytical Chemistry (invited review). Anal. Chem. 87 3−18 (2015). [362]