p370: anthropometric characteristics of postmenopausal women depending on appendicular skeletal mass

1
S198 Poster presentations, Friday 19 September 2014/European Geriatric Medicine 5S1 (2014) S159S234 lower 25(OH) levels (26.1±16.2 nmol/l) than those with normal BMI (34.3±25.3 nmol/l) or moderate obesity. 25(OH)D levels fluctuated throughout the year with a 2-month lag (mean ultraviolet index values for a given month being a reference). The lowest 25(OH)D level was registered during February and March and especially in age group80–89 yrs. whose mean level of 25(OH)D was 10.06±2.13 nmol/L. Less deficient months were August, September. Conclusions: Vitamin D deficiency is widespread in Ukrainian elderly population; age, male sex and BMI all adversely affecting 25(OH)D levels. P370 Anthropometric characteristics of postmenopausal women depending on appendicular skeletal mass V.V. Povoroznyuk, N.I. Dzerovych, R.V. Povoroznyuk D.F. Chebotarev Institute of gerontology NAMS Ukraine, Ukraine The aim of our study was to evaluate the anthropometric characteristics of the postmenopausal women depending on their appendicular skeletal mass. Materials and Methods: We’ve examined 8882 women aged 20–89 years (mean age 56.7±0.14yrs; mean height 162.5±0.07 cm; mean weight 73.5±0.16kg), taken anthropometric measures of 79 examined postmenopausal women aged 40–82 yrs (mean age 63.53±1.08yrs, mean height 157.54±0.79 cm, mean weight 74.75±1.68kg). Appendicular skeletal mass (ASM) was measured at all the four limbs with DXA. We’ve also calculated the appendicular skeletal mass index (ASMI) according to the formula: ASM/height (kg/m 2 ). During the quartile analysis, depending on their ASMI parameters, the examined women were divided into the following groups: Q1 ASMI <6.38 kg/m 2 (n = 20), Q2 ASMI = 6.38– 6.83 kg/m 2 (n = 20), Q3 – ASMI = 6.84–7.36 kg/m 2 (n = 20), Q4 – ASMI >7.36 kg/m 2 (n = 19). Anthropometric characteristics of the women were evaluated according to V.V. Bunak’s method (1941) modified by P.F. Shaparenko (1994). Lean and fat masses were measured with DXA using a Prodigy densitometer, GE. Statistical analysis was performed using the Statistica 6.0 software. Results: Frequency of sarcopenia in the group of women aged 65 yrs and older was 7%. Quartile analysis of women taking into account their ASMI revealed that the women of Q1 and Q2 groups had the following anthropometric characteristics significantly reduced: weight (Q1 70.90 kg, Q2 70.25 kg, Q3 74.75 kg, Q4 85.53 kg; F = 5.24; p = 0.002), neck circumference (Q1 350 mm, Q2 357 mm, Q3 376 mm, Q4 393 mm; F = 5.68; p = 0.001), abdomen circumference (Q1 846 mm, Q2 936 mm, Q3 1008 mm, Q4 1106 mm; F = 11.52; p < 0.0001), shoulder width (Q1 903 un., Q2 963 un., Q3 1029 un., Q4 1078 un.; F = 2.22; p = 0.09), narrow tibia circumference (Q1 221 mm, Q2 227 mm, Q3 244 mm, Q4 248 mm; F = 6.44; p = 0.0006). We also observed a significantly lower thorax circumference in the Q1 group (Q1 903 mm, Q2 963 mm, Q3 1029 mm, Q4 1079 mm; F = 3.82; p = 0.01) in comparison with the women of Q4 group (Q1 903 mm, Q2 963 mm, Q3 1029 mm, Q4 1079 mm; F = 3.82; p = 0.01). Conclusion: In women with a lower ASMI (Q1 and Q2 groups) the following anthropometric characteristics were significantly lower: weight, neck circumference, abdomen circumference, shoulder width, narrow tibia circumference. Thus, we can use the anthropometric measures for determining the groups with the relative risk of sarcopenia and its complications. P371 Does post discharge nutritional support to malnourished geriatric patients affect ADL function? J. Lindegaard-Pedersen 1 , P.U. Pedersen 2 , E.M. Damsgaard 1 1 Aarhus University Hospital, Aarhus C, Denmark; 2 Aalborg University, Aalborg, Denmark Introduction: Low dietary intake in geriatric patients leads to loss of muscle mass, reduced activity of daily living (ADL), and loss of independence. Early discharge makes the continuity of nutritional support increasingly important in order to prevent deterioration and promote recovery. Aim: To investigate if post discharge nutritional support to malnourished geriatric patients affects ADL function. Material and Methods: Patients admitted to an acute geriatric ward, at risk of malnutrition, 75+ years, and living alone, were randomly allocated to nutritional support (home visitor or telephone calls) or to a control group. Exclusion criteria were terminal illness, cognitive impairment, or nursing home residence. The interventions included nutritional counseling and supplement at 1, 2, and 4 weeks after discharge. ADL (Barthel score) was measured at discharge and 8 weeks later. Data were analyzed by multivariate repeated measurements analysis. Results: Barthel data were measured twice in 158 patients (home visit: 52, telephone: 52, and control: 54). Participants were comparable in relation to age, morbidity, and nutritional risk. Mean increase in Barthel score in the home visit group was 10.8 (95% CI: 7.8;13.8), 7 (95% CI: 2.8;11.4) in the telephone group, and 6.4 (95%CI: 1.7;11.1) in controls. The differences were not statistically significant. Conclusion: The Barthel score improved in all groups, but not significantly. Patients receiving home visits increased most. The study may lack power in terms of number of participants included and the follow-up time may be too short to produce significant differences in ADL. P372 Intramuscular adipose tissue and survival in geriatric inpatients S. Perkisas 1 , Y.M. Chong 1 , M. Vandewoude 2 1 ZNA, Belgium; 2 University Antwerp, ZNA, Antwerp, Belgium Introduction: In the current work-up of sarcopenia, muscle mass, strength and functionality are estimated. The measurement of another parameter, the intramuscular adipose tissue (IMAT), gives a new dimension to the interpretation of the muscle mass component. So, not only muscle quantity, but also muscle quality is investigated. In this study, the predictive role of IMAT on one-year survival is examined. Methods: All patients admitted to the geriatric wards of the University department of Geriatrics (site St-Elisabeth hospital) between 01/08/2012 and 31/01/2013 were included. Muscle mass and IMAT were measured by CT scan of the upper leg. At least one year after admission, survival in this cohort was checked through personal contact with patients or their relatives. Results: Of the 303 patients who were admitted, follow-up data was procured of 301 (99.3%). Median follow-up time was 388 days. An all-cause mortality rate of 24.3% (n = 74) was seen. Overall muscle mass was 527±15 grams (range 60–1325grams). Overall IMAT was 29.2±13.0% (range 3.2–86.2%). There was a positive correlation between muscle mass and survival (Spearman’s rho 0.222, p = 0.002), and a negative correlation between IMAT and survival (Spearman’s rho −0.147, p=0.039). Conclusions: There is a negative correlation between IMAT and survival in geriatric inpatients. Since there is a large variance in IMAT when measuring muscle volume, it seems important to make the differentiation between IMAT and muscle mass. In the

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Page 1: P370: Anthropometric characteristics of postmenopausal women depending on appendicular skeletal mass

S198 Poster presentations, Friday 19 September 2014 / European Geriatric Medicine 5S1 (2014) S159–S234

lower 25(OH) levels (26.1±16.2 nmol/l) than those with normal BMI

(34.3±25.3 nmol/l) or moderate obesity. 25(OH)D levels fluctuated

throughout the year with a 2-month lag (mean ultraviolet

index values for a given month being a reference). The lowest

25(OH)D level was registered during February and March and

especially in age group80–89yrs. whose mean level of 25(OH)D

was 10.06±2.13nmol/L.

Less deficient months were August, September.

Conclusions: Vitamin D deficiency is widespread in Ukrainian

elderly population; age, male sex and BMI all adversely affecting

25(OH)D levels.

P370

Anthropometric characteristics of postmenopausal women

depending on appendicular skeletal mass

V.V. Povoroznyuk, N.I. Dzerovych, R.V. Povoroznyuk

D.F. Chebotarev Institute of gerontology NAMS Ukraine, Ukraine

The aim of our study was to evaluate the anthropometric

characteristics of the postmenopausal women depending on their

appendicular skeletal mass.

Materials and Methods: We’ve examined 8882 women aged

20–89 years (mean age 56.7±0.14 yrs; mean height 162.5±0.07 cm;

mean weight 73.5±0.16 kg), taken anthropometric measures of

79 examined postmenopausal women aged 40–82yrs (mean

age 63.53±1.08 yrs, mean height 157.54±0.79 cm, mean weight

74.75±1.68 kg). Appendicular skeletal mass (ASM) was measured at

all the four limbs with DXA. We’ve also calculated the appendicular

skeletal mass index (ASMI) according to the formula: ASM/height

(kg/m2). During the quartile analysis, depending on their ASMI

parameters, the examined women were divided into the following

groups: Q1 – ASMI <6.38 kg/m2 (n =20), Q2 – ASMI = 6.38–

6.83 kg/m2 (n =20), Q3 – ASMI = 6.84–7.36 kg/m2 (n =20), Q4 –

ASMI >7.36 kg/m2 (n =19). Anthropometric characteristics of the

women were evaluated according to V.V. Bunak’s method (1941)

modified by P.F. Shaparenko (1994). Lean and fat masses were

measured with DXA using a Prodigy densitometer, GE. Statistical

analysis was performed using the Statistica 6.0 software.

Results: Frequency of sarcopenia in the group of women aged

65yrs and older was 7%. Quartile analysis of women taking

into account their ASMI revealed that the women of Q1 and

Q2 groups had the following anthropometric characteristics

significantly reduced: weight (Q1 70.90 kg, Q2 70.25 kg, Q3 74.75 kg,

Q4 85.53 kg; F = 5.24; p = 0.002), neck circumference (Q1 350mm,

Q2 357mm, Q3 376mm, Q4 393mm; F =5.68; p = 0.001),

abdomen circumference (Q1 846mm, Q2 936mm, Q3 1008mm,

Q4 1106mm; F =11.52; p < 0.0001), shoulder width (Q1 903un.,

Q2 963un., Q3 1029un., Q4 1078un.; F = 2.22; p = 0.09), narrow tibia

circumference (Q1 221mm, Q2 227mm, Q3 244mm, Q4 248mm;

F =6.44; p = 0.0006). We also observed a significantly lower

thorax circumference in the Q1 group (Q1 903mm, Q2 963mm,

Q3 1029mm, Q4 1079mm; F =3.82; p = 0.01) in comparison with

the women of Q4 group (Q1 903mm, Q2 963mm, Q3 1029mm,

Q4 1079mm; F =3.82; p = 0.01).

Conclusion: In women with a lower ASMI (Q1 and Q2 groups)

the following anthropometric characteristics were significantly

lower: weight, neck circumference, abdomen circumference,

shoulder width, narrow tibia circumference. Thus, we can use

the anthropometric measures for determining the groups with the

relative risk of sarcopenia and its complications.

P371

Does post discharge nutritional support to malnourished

geriatric patients affect ADL function?

J. Lindegaard-Pedersen1, P.U. Pedersen2, E.M. Damsgaard1

1Aarhus University Hospital, Aarhus C, Denmark; 2Aalborg University,

Aalborg, Denmark

Introduction: Low dietary intake in geriatric patients leads to loss

of muscle mass, reduced activity of daily living (ADL), and loss of

independence. Early discharge makes the continuity of nutritional

support increasingly important in order to prevent deterioration

and promote recovery.

Aim: To investigate if post discharge nutritional support to

malnourished geriatric patients affects ADL function.

Material and Methods: Patients admitted to an acute geriatric

ward, at risk of malnutrition, 75+ years, and living alone,

were randomly allocated to nutritional support (home visitor or

telephone calls) or to a control group. Exclusion criteria were

terminal illness, cognitive impairment, or nursing home residence.

The interventions included nutritional counseling and supplement

at 1, 2, and 4 weeks after discharge. ADL (Barthel score) was

measured at discharge and 8 weeks later. Data were analyzed by

multivariate repeated measurements analysis.

Results: Barthel data were measured twice in 158 patients (home

visit: 52, telephone: 52, and control: 54). Participants were

comparable in relation to age, morbidity, and nutritional risk.

Mean increase in Barthel score in the home visit group was 10.8

(95%CI: 7.8;13.8), 7 (95%CI: 2.8;11.4) in the telephone group, and 6.4

(95%CI: 1.7;11.1) in controls. The differences were not statistically

significant.

Conclusion: The Barthel score improved in all groups, but not

significantly. Patients receiving home visits increased most. The

study may lack power in terms of number of participants included

and the follow-up time may be too short to produce significant

differences in ADL.

P372

Intramuscular adipose tissue and survival in geriatric

inpatients

S. Perkisas1, Y.M. Chong1, M. Vandewoude2

1ZNA, Belgium; 2University Antwerp, ZNA, Antwerp, Belgium

Introduction: In the current work-up of sarcopenia, muscle mass,

strength and functionality are estimated. The measurement of

another parameter, the intramuscular adipose tissue (IMAT), gives

a new dimension to the interpretation of the muscle mass

component. So, not only muscle quantity, but also muscle quality is

investigated. In this study, the predictive role of IMAT on one-year

survival is examined.

Methods: All patients admitted to the geriatric wards of the

University department of Geriatrics (site St-Elisabeth hospital)

between 01/08/2012 and 31/01/2013 were included. Muscle mass

and IMAT were measured by CT scan of the upper leg. At least one

year after admission, survival in this cohort was checked through

personal contact with patients or their relatives.

Results: Of the 303 patients who were admitted, follow-up data

was procured of 301 (99.3%). Median follow-up time was 388 days.

An all-cause mortality rate of 24.3% (n =74) was seen. Overall

muscle mass was 527±15 grams (range 60–1325grams). Overall

IMAT was 29.2±13.0% (range 3.2–86.2%). There was a positive

correlation between muscle mass and survival (Spearman’s rho

0.222, p = 0.002), and a negative correlation between IMAT and

survival (Spearman’s rho −0.147, p = 0.039).

Conclusions: There is a negative correlation between IMAT and

survival in geriatric inpatients. Since there is a large variance

in IMAT when measuring muscle volume, it seems important to

make the differentiation between IMAT and muscle mass. In the