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Chapter1

Chapter2

Fish  oil

Raynaud’ssyndrome

Blood  viscosity

Platelet  aggregability

Vascular  reactivity

Fish  oil

Raynaud’ssyndrome

Can  reduce

Reduces(and  co-occurs)

Increased(and  co-occurs)

1† 2† 3 1

3 4 3,5 6 3 2

1,2!

1

2

3

4

5

6

! †

1% 10% 25%

A

B

VI

VII

X

VIII

IX

V

III

IIIXXI

XIX IV

XX

XIII

XVII

XIV

XIIXI

XVIII

XIII XXI

XIV

VIII

XII

XV

IX

V

III

VII

VI

IV

XXI

XVI

XVIII

II

XVII

XX

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Chapter4

Gene translocation Histone modificationDNA methylation DNA repairCopy number variation Transposon activation

DNA

RNA stabilityAlternative RNA splicingRetrotransposonsRNA

Transcription

Transcription factors Protein degradation

Protein

InheritanceDevelopmentGrowthAging

CancerDiabetes, obesityInfertilityRespiratory diseasesAlergies, immune responseNeurodegenerative disordersStress response

Pharmaceuticals

PesticidesAir pollutants

Heavy metalsHormones

NutritionRadiation

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