otransmucpat: aw approach to manage periodontal care€¦ · 18/07/2011 · periodontal disease is...

Complete Periodontal Therapy

"First Line" Topical Therapy for Periodontal TreatmentOral Transmucosal Patch: A new approach to manage periodontal care

07. STMN_periopatch new brochure 110718 - EN.indd 1 5-10-2018 14:25:02

Efficacy-based Periodontal Therapy:Periodontal disease is a multifactorial inflammatory disease

Periodontal disease can be effectively treated only by:

: Leading the way to better oral care.Current therapies, including scaling

and root planing, antiseptic rinses

and even subgingivally-delivered

antimicrobials, reduce bacterial load

but do not reduce inflammation

or enhance healing.

Reducing bacterial plaque

Reducing inflammation to arrest the

disease

Promoting healing to repair the damage

PerioPatch is the first product to accomplish all of these crucial objectives.

AfterBefore PerioPatch applied


% R

educ

tion

in in

flam

mat

ion

SRP only PP+SRP

p value = 0.00160%

50%

40%

30%

20%

10%

0%

Placebo PerioPatch®

p value = 0.0160%

50%

40%

30%

20%

10%

0%

-10%

% R

educ

tion

in G

CF

ß-gl

ucur

onid

ase

% o

f pat

ient

s w

ith in

crea

sed

MM

P

p value = 0.0028100%

80%

60%

40%

20%

0%

Placebo PerioPatch®

: Breakthroughin Oral CareHow Doesit Work?

PerioPatch is a topical patch that adheres and conforms to the teeth

and gums.

It protects the gingival tissue and rapidly reduces the signs and symptoms

of inflammation.

Based on new medical technology developed to accelerate healing in

chronic wounds, PerioPatch absorbs the inflammatory exudates from both

the periodontal pocket and the gingiva. The therapeutic effect is a rapid

reduction of inflammation and acceleration of the natural healing process.

PerioPatch®

(PP) reduces

inflammation 3-fold

when combined

with scaling and

root planing (SRP)

50% reduction in

GCF β-glucuronidase

(a clinical biomarker

of active inflammation)

within 24 hours

Lower levels of

MMP (an enzyme

that causes

periodontal

destruction)

with PerioPatch®

treatment

Graph 1

Graph 2

Graph 3


works from the "outside-in"Reverse patch technology designedfor oral care: adheres when moist (in mouth)and not when dry.

One treatment (6 patches): Therapeutic benefits continue for months.Benefits: Protects and relieves inflamed gums

Reduces pocket depth

Increases clinical attachment

Reduces bleeding and pain

Relieves denture sores and other oral irritation

Promotes healing after surgery and implants

Absorbs inflammatory exudates

Can be used together with scaling and root planing

for better clinical results

Can be used to manage peri-implantitis

Can be used to manage moderate recession

Rapid and long-lasting effect

Easy to use

Comfortable

Safe

Easy to apply by both professional and patient

No need for painful insertion into the inflamed periodontal pocket

Comfortable to wear

Rapid effect

Before

After


Thousands of patients treated successfully

Natural hydrogel technology Easily integrated into current treatment regimens Safe for long term use

Centella asiatica

Sambucus nigra

Echinacea purpurea


Dosage:PerioPatch is applied topically to the affected area 1-3 per day.

The patch will remain in place for 15 – 120 minutes and will self-release when therapeutic action is completed.

Patients should not eat, drink, or rinse when PerioPatch is adhered to the gums.

Regulatory status:PerioPatch is a registered medical device

(FDA 510(k); CE Class I)

Professor Howard Tenenbaum, DDS, PhD, Professor, Faculty of Dentistry, University of Toronto

"PerioPatch is a wonderful new product that can be used to treat periodontal disease

by reducing inflammation and promoting healing. It has become a critical part of our

periodontal treatment regimen."

Jeffrey C Hoos DMD FAGD

Success in private practice is assured when the

office performs the BALANCING act between Art,

Science, and Business.

"By adding PeriActive to our pre and post surgical

cases, everything is just better. The tissues look

healthier, heal better and post operative discomfort

is greatly reduced. Patients are extremely pleased

with the results. PerioPatch has given us another

tool to solve muco-gingival problems, as well as

post surgical comfort. With IZUN products, we

have a great partnership to help maintain the

BALANCING: Art, Science, and Business."

John Comisi, DDS, Assistent Professor, Medical University of South Carolina

Dr. Comisi recommends PerioPatch, a thin bilayer

oral patch that works together with a combination

of three botanical ingredients (Sambucus nigra,

Echinacea purpurea, and Centella asiatica) to calm any

inflammation and enhance natural oral healing.

The patch has been beneficial for his patients,

helping to reduce acute inflammation and

improve overall oral health.

What Key Opinion Leadersare saying about PerioPatch:


Complete Periodontal Therapy (CPT)Treats all aspects of gum disease with a three-pronged approach:

Reduces bacterial plaque

Reduces inflammation

Promoteshealing

1 2 3

CPT is an Oral Care system:

Full mouth use and long-term maintenance

PerioPatch®A unique intra-oral patch for highly inflamed gums and deep pockets

1 2


References for graphsGraph 1. Paquette DW, Levine WZ. Adjunctive Treatment of Periodontal Disease with Self-Adhesive Hydrogel Wound

Dressing: Case Series. Compend Contin Educ Dent. 2015 Jun;36(6): e12-4.

Graph 2. Samuels N, Saffer A, Wexler ID, Oberbaum M. Localized reduction of gingival inflammation using site-specific

therapy with a topical gingival patch. J Clin Dent. 2012;23(2):64-7

Graph 3. Oberbaum M, Levine WZ, Saffer AJ, Koren N, Sarment D (2016) Inhibition of matrix metalloproteinase activity by a

transmucosal patch containing botanical compounds. Dent Oral Craniofac Res 2: DOI: 10.15761/DOCR.1000175.

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DISTRIBUTED BY

Institut Straumann AGPeter Merian-Weg 12 | 4002 Basel | SwitzerlandTel +41 61 965 11 11 | Fax +41 61 965 11 01E-mail: [email protected] | www.straumann.com


otransmucpat: aw approach to manage periodontal care€¦ · 18/07/2011 · periodontal disease is...

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