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  • P e d i a t r i a P o l s k a t o m 8 7, n r 1 , s t y c z e l u t y 2 0 1 2

    PODYPLOMOWA SZKOA PTP / POSTGRADUATE SCHOOL OF PAEDIATRICS72

    Optimizing Use of the Complete Blood Count

    Optymalne stosowanie badania morfologicznego krwi

    Bruce M. Camitta, Rebecca Jean Slye

    ABSTRACTThe CBC is more than a collection of numbers. Understanding its strengths and limitations provides more useful in-formation. When used in conjunction with careful review of the peripheral smear and a limited number of other tests, the CBC can be a more effective diagnostic tool.Key words: complete blood counts (CBC)

    STRESZCZENIEBadanie morfologiczne krwi nie stanowi jedynie zbioru liczb. Poznanie jego zalet i ogranicze umoliwia zdobycie wielu przydatnych informacji. Badanie wykonane wraz z dokadnym rozmazem krwi obwodowej oraz kilku innymi testami moe by bardzo przydatnym narzdziem diagnostycznym.Sowa kluczowe: badanie morfologiczne krwi, morfologia krwi obwodowej

    Pediatr Pol 2012; 87(1): 7277

    2012 by Polskie Towarzystwo Pediatryczne

    Otrzymano/Received: 20.11.2011

    Zaakceptowano do druku/Accepted:

    20.12.2011

    Midwest Center for Cancer and Blood Disorders

    Department of Pediatrics

    Konflikt interesu/ Conflicts of interest:

    Autorzy pracy nie zgaszaj konfliktu interesw

    Adres do korespondencji/ Address for

    correspondence: Bruce M. Camitta

    Medical College of Wisconsin and Childrens

    Hospital of Wisconsin 8701 Watertown Plank Road

    Milwaukee, Wisconsin, USA 53226

    Tel.: 414-456-4106 Fax: 414-456-6543

    e-mail: bcamitta@mcw.edu

    Presented at the 2nd Polish-American Meeting of Pediatricians; Rzeszw, Poland: May 2829, 2010

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    Table I. Relationship of age and normal MCV Tabela I. Prawidowe MCV w zalenoci od wieku dziecka

    Term newborn 104118 fl

    32 week premature 105125 fl

    Age Lowest normal MCV

    1218 mo 70 fl

    1848 mo 74 fl

    47 yr 76 fl

    812 yr 78 fl

    >12 yr 80 fl

    Adult normal 8095 fl

  • P e d i a t r i a P o l s k a t o m 8 7, n r 1 , s t y c z e l u t y 2 0 1 2

    PODYPLOMOWA SZKOA PTP / POSTGRADUATE SCHOOL OF PAEDIATRICS 73

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    Table II. Differential diagnosis of macrocytic anemia Tabela II. Rnicowanie niedokrwistoci makrocytarnej

    Spurious newborn, reticulosis

    Nonmegaloblastic liver disease, marrow aplasis, hypothyroidism, copper deficiency, ethanol

    Megaloglastic B12 deficiency, folate deficiency

    orotic aciduria, B6 deficiency, thiamine deficiency, erythroleukemia

    Table III. Differential diagnosis of microcytic anemia Tabela III. Rnicowanie niedokrwistoci mikrocytarnej

    Common iron deficiency, thalassemias, lead poisoning (usually with iron deficiency), chronic disease

    Rare B6 diseases, copper deficiency, atransferrinemia, sideroblastic anemias

    Table IV. Differential diagnosis of iron deficiency versus thalas-semia trait Tabela IV. Rnicowanie niedoboru elaza i talasemi

    Iron deficiency diet, pica, bleedingserum paleMCV 4580MCV/RBC .13Fe low: Fe/IBC 515%RDW highNL/low A2: NL F HGBmicrocitosis and poikilocytosis

    B-Thalassemia Trait +family historyserum color normalMCV 5570MCV/RBC

  • P e d i a t r i a P o l s k a t o m 8 7, n r 1 , s t y c z e l u t y 2 0 1 2

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