Myoung Joon Kim, MD1 Len Zheleznyak, MS2

Scott M. MacRae, MD2 Geunyoung Yoon, PhD2

1University of Ulsan College of Medicine, Asan Medical Center, Seoul,

Korea

2Flaum Eye Institute, University of Rochester, Rochester, NY, USAM. J. K. and L. Z. have no financial or proprietary interest in any material or method

mentioned.

S. M. M. and G. Y. are consultants of Bausch and Lomb.

S. M. M. is a consultant of Acufocus and Technolas.

This study was performed to evaluate optical quality and through focus performance

of premium intraocular lenses.

Premium Intraocular Lenses

expanded range of vision

spectacle freedom

Optical Bench Testing of IOLs in Wet Cell IOL Mount

Direct Retinal Image Quality Measurement

L1 AP L2 L3

PC

ATWC &IOL

L5

IS

AFRT

TL

AFRT; Air Force resolution target, L1; Lens 1, L2; Lens 2, L#; Lens #, AP; artificial pupil, PC; pupil camera, AT; alignment target, TL; trial lens,

WC; wet cell, IOL; intraocular lens, IS; image sensor

Cropped for Analysis1951 US Air Force Resolution

Target

Premium IOLs

AcrySof ReSTORAcrySof ReSTORAlconAlcon

ReZoomReZoomAbbottAbbott

apodized diffractive aspheric multifocal IOL

refractive multifocal IOL

TecnisTecnisAbbottAbbott

diffractive aspheric multifocal IOL

CrystalensCrystalensBausch & LombBausch & Lomb

HD500

SN6AD3 (+4.0 add) SN6AD1 (+3.0 add) ZM900

accommodative multifocal IOL

NXG1

SofPort AOSofPort AOB&LB&L

LI60AOVaberration-free monofocal IOL

(reference lens)

AcrySof AcrySof NaturalNaturalAlconAlcon

SN60ATspherical monofocal IOL

Controls

20D IOLs

LI60AOV = SofPort AO, SN60AT = AcrySof spherical, SN6AD3 = ReSTOR +4D, SN6AD1 = ReSTOR +3D, NXG1 = ReZoom, ZM900 = Tecnis multifocal, HD500 = Crystalens HD

Defocus

LI60AOV = SofPort AO, SN60AT = AcrySof spherical, SN6AD3 = ReSTOR +4D, SN6AD1 = ReSTOR +3D, NXG1 = ReZoom, ZM900 = Tecnis multifocal, HD500 = Crystalens HD

Defocus

LI60AOV = SofPort AO, SN60AT = AcrySof spherical, SN6AD3 = ReSTOR +4D, SN6AD1 = ReSTOR +3D, NXG1 = ReZoom, ZM900 = Tecnis multifocal, HD500 = Crystalens HD

Defocus

SAO = SofPort AO, ASS = AcrySof spherical, RS4 = ReSTOR +4D, RS3 = ReSTOR +3D,REZ = ReZoom, TEC = Tecnis multifocal, CLH = Crystalens HD

Cross-correlation coefficients (CCC) between the perfect and actual images were computed as an image quality metric to quantify image quality and are ranged from 0 (worst) to 1 (best).

SAO = SofPort AO, ASS = AcrySof spherical, RS4 = ReSTOR +4D, RS3 = ReSTOR +3D,REZ = ReZoom, TEC = Tecnis multifocal, CLH = Crystalens HD

Summary

Image Quality for Distant Objects4 mm PupilSAO > ASS ≈ CLH > RS4 ≈ RS3 > TEC > REZ

Image Quality for Intermediate Objects4 mm Pupil, ~ 1 DCLH > TEC ≈ ASS > SAO ≈ REZ > RS4 ≈ RS3

Image Quality for Near Objects of Multifocal IOLs3 mm PupilRS3 > TEC ≈ REZ > RS4

Working Distance for Near Objects of Multifocal IOLs3 mm PupilRS4 ≈ TEC < REZ < RS3

Conclusion

Thank you!