optic nerve and opthalmic artery

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    Optic nerve and opthalmic artery

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    Cranial Nerve II: Optic

    y Arises from the retina

    of the eye

    y Function: sensory -

    solely for visiony Exits through optic

    canal

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    y The optic nerve is the second cranial nerve

    y It arises from the optic chiasma on the floor of the diencephalon

    y Enters the orbit through the optic canal, accompanied by the

    ophthalmic artery

    y It changes its shape from being flattened at the chiasma to

    rounded as it passes through the optic canal

    y Nerve is extension of brain covered by meninges

    y Length: 4 cm ; 2.5 mm intraorbital and 5 mm intracanalicular

    and 10 mm intracranial

    yIn the orbit it passes forwards, laterally and downwards, andpierces the sclera 3mm medial to the posterior pole

    y It has a somewhat tortuous course within the orbit to allow for

    movements of the eyeball

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    y Special somatic afferents (SSA) are found only in supraspinal locationsand are represented by the laterally-lying vestibular and auditory nucleiin the medulla and pons.

    y They develop from branchial arch structures.

    Cranial nerves I and II serve vision (SSA) and olfaction (SVA)

    y However, these are not true nerves.

    y Rather they develop as evaginations of the telencephalon (olfactorynerve) and the diencephalon (optic nerve)

    y I I(optic) SSA:

    y Originates in ganglion cells of retina

    y Lateral geniculate nucleus and superior colliculus

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    y The optic nerve or nerve of sight, consists mainly of fibers

    derived from about 1.2 million ganglionic cells of the retina

    y These axons terminate around the cells in the lateral geniculate

    body, pulvinar, and superior colliculus which constitute the loweror primary visual centers

    y From the cells of the lateral geniculate body and the pulvinar

    fibers pass to the cortical visual center, situated in the cuneus and

    in the neighborhood of the calcarine fissure

    y There are also a few fine fibers, afferent fibers, extending from

    the retina to the brain, that are supposed to be concerned in

    pupillary reflexes

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    Relationsy The optic nerve has important relationships with other orbital structure

    y As it leaves the optic canal, it lies superomedial to the ophthalmic artery,and is separated from lateral rectus by the oculomotor, nasociliary and

    abducens nerves, and sometimes by the ophthalmic veins

    y The optic nerve is closely related to the origins of the four recti muscles,

    whereas more anteriorly, where the muscles diverge, it is separated fromthem by a substantial amount of orbital fat

    y Just beyond the optic canal, the ophthalmic artery and the nasociliary

    nerve cross the optic nerve to reach the medial wall of the orbit

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    y The central artery of the retina enters the substance of the optic

    nerve inferomedially about 1.25 cm behind eye ball

    y Near the back of the eye, it becomes surrounded by long andshort ciliary nerves and vessels

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    y Medial palpebral branch: supply eyelids

    y Dorsal nasal branch supply upper part of nose

    y Optic nerve has no neurilemmal sheathy It has no power of regeneration

    y It is tract

    y Optic nerve atrophy is damage to the optic nerve

    y The optic nerve can also be damaged by shock, various toxic

    substances, radiation, and trauma

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    Opthalmic artery

    y The main vessel supplying orbital structures is the

    ophthalmic artery

    y Its terminal branches anastomose on the face and scalp with

    those of the facial, maxillary and superficial temporalarteries,

    y Establishing connections between the external and internal

    carotid arteries

    y

    In addition to the ophthalmic artery, the infraorbital branchof the maxillary artery, and possibly the recurrent meningeal

    artery, supply orbital structures

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    y The ophthalmic artery leaves the internal carotid artery as it

    quits the cavernous sinus medial to the anterior clinoid process

    y It enters the orbit by the optic canal, inferolateral to the opticnerve

    y It crosses between the optic nerve and superior rectus to reach

    the medial wall of the orbit, running between superior oblique

    and medial rectus.

    y At the medial end of the upper eyelid, it divides into

    supratrochlear and dorsal nasal branches

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    y As it crosses the optic nerve with the nasociliary nerve, it is

    separated from the frontal nerve by superior rectus and levator

    palpebrae superiorisy In c.15% of subjects the ophthalmic artery crosses below the

    optic nerve

    y It has the following branches:

    y Central artery of the retina, lacrimal artery, muscular branches,ciliary arteries, supraorbital artery, posterior ethmoidal artery,

    anterior ethmoidal artery, meningeal branch, medial palpebral

    arteries, supratrochlear artery, dorsal nasal artery

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    y Central artery of the retina :The small central artery of the

    retina is the first branch

    y It begins below the optic nerve and for a short distance

    y it lies in the dural sheath of the nerve

    y It enters the inferomedial surface of the nerve c.1.25 cm behind

    the eye

    y Runs to the retina along its a muscular branches

    y The central retinal artery supplies all the nerve fibers that form

    the optic nerve

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    y There are three groups of ciliary arteries: long and short posterior, and

    anterior

    y Long posterior ciliary arteries, usually two, pierce the sclera near the optic

    nerve, pass anteriorly along the horizontal meridian and join the greaterarterial circle in the iris

    y About seven short posterior ciliary arteries pass close to the optic nerve to

    reach the eyeball where they divide into 15-20 branches

    y T

    hey pierce the sclera around the optic nerve to supply the choroid, andanastomose with twigs of the central retinal artery at the optic disc

    y Anterior ciliary arteries :They reach the eyeball on the tendons of the recti,

    form a circumcorneal subconjunctival vascular zone, and pierce the sclera

    near the sclerocorneal junction to end in the greater arterial circle of the iris

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    y The lacrimal artery is a large branch which usually leaves the

    ophthalmic artery near its exit from the optic canal

    y It accompanies the lacrimal nerve along the upper border of

    lateral rectus, supplies and traverses the lacrimal gland, and

    ends in the eyelids and conjunctiva as the lateral palpebral

    arteries

    y Lacrimal artery gives off one or two zygomatic branches

    y One reaches the temporal fossa via the zygomaticotemporalforamen, and anastomoses with the deep temporal arteries.

    y The other reaches the cheek by the zygomaticofacial

    foramen, and anastomoses with transverse facial arteries

    y A recurrent meningeal branch, usually small, passes back via

    the lateral part of the superior orbital fissure to anastomosewith a middle meningeal branch

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    y The supraorbital artery leaves the ophthalmic artery where it crosses

    the optic nerve

    y Ascends medial to superior rectus and levator palpebrae superioris

    y It passes through the foramen and divides into superficial and deep

    branches which supply the skin, muscles and frontal periosteum

    y It supplies superior rectus and levator palpebrae superioris, and sends

    a branch across the trochlea to the medial canthus

    y The posterior ethmoidal artery runs through the posterior ethmoidalcanal and supplies the posterior ethmoidal air sinuses

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    y The anterior ethmoidal artery passes with its accompanyingnerve through the anterior ethmoidal canal to supply ethmoidal

    and frontal air sinusesy The supratrochlear artery is a terminal branch of the ophthalmic

    artery

    y It leaves the orbit superomedially with the supratrochlear nerve,

    ascends on the forehead to supply the skin, muscles andpericranium, and anastomoses with the supraorbital artery andwith its contralateral fellow

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    Applied

    y Optic neuritis is inflammation of the optic nerve.

    y It may cause sudden, reduced vision in the affected eye

    y Sudden inflammation of the nerve connecting the eye and the

    brain (optic nerve) can injure the insulation surroundingeach nerve fiber, causing the nerve to swell

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    y Optic neuritis most commonly develops due to an autoimmune

    disorder that may be triggered by a viral infection, vitamin B

    deficiency

    y Ocular stroke commonly is caused by embolism of the retinal artery

    y Retinal artery occlusion represents an ophthalmologic emergency, and

    delay in treatment may result in permanent loss of vision

    y Acutely, obstruction of the central retinal artery results in inner layer

    edema and damage of the ganglion cell nuclei

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    y The ciliary ganglion is a parasympathetic ganglion which is concernedfunctionally with the motor innervation of certain intraocular muscles

    y It is a small, flat, reddish-grey swelling, 1-2 mm in diameter,connected to the nasociliary nerve,

    y located near the apex of the orbit in loose fat c.1 cm in front of themedial end of the superior orbital fissure

    y It lies between the optic nerve and lateral rectus, usually lateral to theophthalmic artery

    y Its neurones, which are multipolar, are larger than in typicalautonomic ganglia; a very small number of more typical neurones arealso present

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    y Its connections or roots enter or leave it posteriorly

    y Eight to ten delicate filaments, termed the short ciliary nerves,emerge anteriorly from the ganglion arranged in two or three bundles,the lower being larger

    y They run forwards sinuously with the ciliary arteries, above and belowthe optic nerve, and divide into 15-20 branches

    y Pierce the sclera around the optic nerve and run in small grooves onthe internal scleral surface

    y They convey parasympathetic, sympathetic and sensory fibres betweenthe eyeball and the ciliary ganglion: only the parasympathetic fibressynapse in the ganglion