opioid use disorder and suicide risk use...david j. berman, mph, mpa vice president, mental health...

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OPIOID USE DISORDER AND SUICIDE RISK

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Page 1: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

OPIOID USE DISORDER AND SUICIDE RISK

Page 2: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

An estimated 43.8 million adults aged 18 and older in the United States have a diagnosed mental illness, and 17.5 million have an SMI (8% of total population)

An estimated 24.6 million Americans aged and older need treatment for substance use

1210

Page 3: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

The total estimated annual cost for mental health and substance use treatment in the United States is $280 billion

Untreated MHDs and SUDs in the United States have an estimated annual economic impact of $650 billion in costs related to crime, lost or reduced productivity, and increased healthcare expenses

Page 4: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

As of today, Depression has surpassed all physical diseases

as the major cause of disability worldwide.

Page 5: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 6: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 7: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Toxic stress and traumatic

experiences have been linked to

mental illnesses such as anxiety

disorders and depression, as

well as the exacerbation of other

existing mental health disorders.

Page 8: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

In a critical event, 30-40% of

the impacted population will

likely have a new incident

based mental health disorder.

Page 9: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

• Economic stress

• Social isolation

• Decreased access to systems of support

• Political and social outcomes

• Barriers to treatment

External Influencers During the COVID-19 Pandemic…

Page 10: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

The Sacramento Bee: March 27, 2020

National increase in

suicide prevention hotline call volume was

300%

40% increase in messages

to Crisis Text Line

SAMHSA National

Helpline calls increased five-fold

Page 11: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Compared to 2018, in

April 2020, adults were

three times more likely

to fit criteria for

moderate or serious

mental distress (70.4%

vs. 22.0%).

https://time.com/5833619/mental-health-coronavirus/

Page 12: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

America’s Mental Health Pulse Survey: Harris Poll – April 2020

Page 13: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

37% of adults in the US report symptoms of severe anxiety

Nearly 29% of adults in the US report symptoms of depression

CDC Household Pulse Survey: November 15 – 21, 2020

Page 14: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 15: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 16: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 17: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 18: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 19: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Indiana Screening Data 2020

Page 20: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

81,755

Total Indiana Screenings: Jan 2015 – Nov 2020

Page 21: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Age of Individual Completing Screening (2015 - 2020)

27.74%

30.72%

21.23%

10.46%

5.80%

3.15%0.91%

0.00%

5.00%

10.00%

15.00%

20.00%

25.00%

30.00%

35.00%

11 - 17 18 - 24 25 - 34 35 - 44 45 - 54 55 - 64 65 +

Page 22: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

62,38176.12%

Positive or Moderate to Severe

23.88%%Negative or

Minimal to Mild

Screen Result Severity (2015 - 2020)

Page 23: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Total Screenings Comparison

2015 - 2020 April 2020 – Nov 2020

27,269 (33% of total)81,755

Page 24: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

0

5,000

10,000

15,000

20,000

2020 2019

8,747

1,761

2,143

414

4,767

790

Depression Bipolar Disorder Anxiety

Positive or Moderate to Severe Screening:8 Month Comparison (April to November)

428% increase

Page 25: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 26: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

4:52:20 PM

Every 28 seconds in the U.S....... there is a suicide attempt

(nearly 3,100/day)

Page 27: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

16.1

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IndianaUSA

Slide created by CW Drapeau (2020)

Crude Suicide Rates, Indiana and USA, 1968-2018

Indiana: 51% increase9%

Page 28: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 29: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 30: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 31: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 32: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Early detection saves lives!

Page 33: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 34: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 35: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 36: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 37: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

OPIOID USE SUICIDEOPIOID USE

AND SUICIDE

Page 38: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

The United States has nearly 5 times the rate of death from drug overdoses as other comparable countries (including the UK, Canada, Australia, Austria, France, and Switzerland)

Page 39: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

According to the CDC, opioids were involved in

more than 69,000 overdose deaths in 2019 (two-thirds of

all drug overdose deaths).

Page 40: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

An estimated 30-40% of opioid overdose deaths are

likely suicides.

N Engl J Med. 2018 Apr 26;378(17):1567-1569

Page 41: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

It is often difficult to assess the intentions of an individual who has died of an overdose, other than circumstantially…unless…

• Note

• Conversation

• Social Media Post

Page 42: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

In a 2019 joint study between Harvard University and McLean

Hospital examining individuals who had recently overdosed on

opioids, nearly 60% of participants said that on some level, they

had at least some desire to die before their most recent

overdose, with 36% having a strong desire to die.

Connery, H.S., Taghian, N., Kim, J., Griffin, M., Rockett, I.R.H., Weiss, R.D., Kathryn McHugh, R. (2019). Suicidal motivations reported by opioid overdose survivors: A cross-sectional study of adults with opioid use disorder. Drug and Alcohol Dependence

Page 43: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Opioid use is associated with an increased likelihood of:

• 40-60% for suicidal ideation

• 75% for suicide attempt

• 1300% for death by suicide

J Psychiatr Res. 2017 Sep;92:1-7. doi: 10.1016/j.jpsychires.2017.03.011. Epub 2017 Mar 19.

Page 44: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

• Individuals with OUDs often live on a continuum between wanting to live to wanting to die

• Feelings can waver

Page 45: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Walking a tightrope...

Page 46: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 47: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,
Page 48: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Individuals suffering from chronic

pain are at an increased risk of

suicide simply because of their pain

Page 49: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

While there is limited research on the

effectiveness of strategies to prevent suicide

among individuals with chronic pain, there is

strong evidence to support comprehensive

suicide risk screening and assessment as a

means of identifying those at risk.

Page 50: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Traditionally, suicide and overdose

prevention in OUD involves stratifying

risk based on certain demographic and

clinical factors – however, this fails to

capture the full picture.

Page 51: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

• The presence of acute withdrawal or craving

• Changes in patterns of opioid use

• Loss of identity, sense of belonging, or social supports; shame; humiliation; insomnia

• Increased use of other substances

• Recent personal or situational events, such as legal problems, or relationship conflict

Maruti S, Desjardins I, Bagge CL, Althoff RR. Commentary: opioid use disorder and suicide: an important opportunity to address two significant public health epidemics [published online October 21, 2019]. Prev Med. doi:10.1016/j.ypmed.2019.105854

Page 52: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Several decades of research show that

MAT accompanied by counseling can

reduce opioid overdose-related suicides.

Page 53: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

• Opioid related suicide can still occur even when at-risk persons receive MAT

• Risk of death among those receiving MAT are highest when the medication is initiated and when the treatment is suddenly stopped

• Prevention efforts should involve addressing these critical transition periods

Page 54: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Clinical level prevention strategies include conducting comprehensive suicide risk screening and assessment

Page 55: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

Provision of appropriate treatment

Page 56: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

N Engl J Med 2019; 380:71-79 DOI: 10.1056/NEJMra1802148

Page 57: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

• Educating medical providers on safe prescribing practices

• Increasing public awareness of non-medication strategies to address pain, and subsequently identifying and implementing appropriate strategies

• Hospitalization, if needed

Other clinical level prevention strategies:

Preventing Opioid Abuse, Overdose, and Suicide in Chronic Pain Patients: CAPT; SPRC; SAHMSA

Page 58: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

• Increased access to treatment

• Comprehensive case management

• Vocational rehabilitation

• Legal and housing assistance

Community level prevention strategies:

Preventing Opioid Abuse, Overdose, and Suicide in Chronic Pain Patients: CAPT; SPRC; SAHMSA

Page 59: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

On all levels, follow-up is a key component of

prevention.

Page 60: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

...if you feel overwhelmed, stressed, or frustrated.

Page 61: OPIOID USE DISORDER AND SUICIDE RISK Use...David J. Berman, MPH, MPA Vice President, Mental Health America of Indiana Executive Director, Indiana Suicide Prevention Network Director,

David J. Berman, MPH, MPAVice President, Mental Health America of IndianaExecutive Director, Indiana Suicide Prevention NetworkDirector, Depression and Bipolar Support Alliance of IndianaState Program Manager, Indiana Crisis Counseling Program

[email protected]

@DJBerman

/david-j-berman/