ophtha - eor and lens
DESCRIPTION
ophtha - eor & lensTRANSCRIPT
ERROR OF REFRACTIONERROR OF REFRACTION
OutlineOutlineI. IntroductionI. Introduction
A. OpticsA. OpticsB. RefractionB. RefractionC. Emmetropia and AmetropiaC. Emmetropia and Ametropia
II. General Symptomatology II. General Symptomatology III. Errors of RefractionIII. Errors of Refraction
A. HyperopiaA. Hyperopia B. MyopiaB. Myopia C. AstigmatismC. Astigmatism D. EOR secondary to AgingD. EOR secondary to Aging E. Congenital EORE. Congenital EOR F. Iatrogenic EORF. Iatrogenic EOR
IV. Measurement of EORIV. Measurement of EORV. ManagementV. Management
LENS - a device LENS - a device which causes which causes light to either converge and
concentrate or to diverge, usually formed from a
piece of shaped glass
OPTICSOPTICS
OPTICSOPTICS
POSITIVE OR CONVERGING LENSPOSITIVE OR CONVERGING LENS
If the lens is If the lens is biconvex or plano-convexbiconvex or plano-convex, a collimated or parallel , a collimated or parallel beam of light travelling parallel to the lens axis and passing beam of light travelling parallel to the lens axis and passing through the lens will be converged (or focused) to a spot on through the lens will be converged (or focused) to a spot on
the axis, at a certain distance behind the lens. the axis, at a certain distance behind the lens.
NEGATIVE OR DIVERGING LENSNEGATIVE OR DIVERGING LENSIf the lens is biconcave or plano-concave, a collimated beam If the lens is biconcave or plano-concave, a collimated beam
of light passing through the lens is diverged (spread)of light passing through the lens is diverged (spread)
The beam after passing through the lens appears to be The beam after passing through the lens appears to be emanating from a particular point on the axis in front of the emanating from a particular point on the axis in front of the
lenslens
Diopter Diopter - is the standard unit to express - is the standard unit to express the refractive power of optical lenses. the refractive power of optical lenses. It is the reciprocal of the distance, It is the reciprocal of the distance, expressed in meters, between a lens expressed in meters, between a lens and its focus (its focal length)and its focus (its focal length)
D = 1D = 1
ff
D: diopterD: diopter f: focal length (in f: focal length (in meters)meters)
OPTICSOPTICS
Focal length = 1 meter D = 1/1
D = 1 diopter
Focal length = 0.5 meterD = 1/0.5
D = 2 diopters
Focal length = 0.25 meterD = 1/0.25
D = 4 diopters
Example:
D = 1/f
OPTICSOPTICSMAIN OPTICAL MAIN OPTICAL
COMPONENTS COMPONENTS OF THE EYE:OF THE EYE:
Cornea 43 DCornea 43 D
Lens 17 DLens 17 D
The anterior surface of the cornea is the major refractive surface of the eye
DEFINITION OF TERMS:DEFINITION OF TERMS:Emmetropia Emmetropia
optical condition in which an eye does optical condition in which an eye does not have an error of refractionnot have an error of refraction
Light from a distant object is focused on Light from a distant object is focused on the retina.the retina.
AMETROPIAAMETROPIA
optical condition in which parallel rays of optical condition in which parallel rays of light from an object an infinite distance light from an object an infinite distance from the eye does not come to focus from the eye does not come to focus (form an image) exactly at the retina(form an image) exactly at the retina
Three general types: HYPEROPIA, MYOPIA AND Three general types: HYPEROPIA, MYOPIA AND ASTIGMATISMASTIGMATISM
Ammetropia
Axial ametropiaAxial ametropia - Abnormal length of - Abnormal length of the globethe globe
Curvature AmetropiaCurvature Ametropia - Abnormal - Abnormal curvature of the cornea or the lenscurvature of the cornea or the lens
Index AmetropiaIndex Ametropia - Abnormal - Abnormal refractive indices of the mediarefractive indices of the media
Abnormal position of the lensAbnormal position of the lens
GENERAL SYMPTOMATOLOGYGENERAL SYMPTOMATOLOGY
Decreased visual acuity
Pin hole test
Ocular discomfort
increased sensitivity to light, decreased efficiency, various aches and fatigue
Headache
HYPEROPIAHYPEROPIA
FarsightednessFarsightedness
The refractive power of the The refractive power of the cornea and lens are weak, or a cornea and lens are weak, or a relatively short eyeballrelatively short eyeball
light from distant objects focus light from distant objects focus behind the retina behind the retina
Axial Hyperopia - the eyeball is Axial Hyperopia - the eyeball is shorter than averageshorter than average
Hyperopia
Accomodation increases the Accomodation increases the refractive power of the lens and refractive power of the lens and may compensate for hyperopiamay compensate for hyperopiaHeadache – due to excessive Headache – due to excessive sustained accomodation required sustained accomodation required for clear visionfor clear vision
Corrected by: Corrected by: Convex lensesConvex lenses
HyperopiaHyperopia
MYOPIAMYOPIANearsightednessNearsightedness
The refractive power of the cornea The refractive power of the cornea and lens are too strong, or a and lens are too strong, or a relatively long eyeballrelatively long eyeball
light from distant objects focus in light from distant objects focus in front of the retina front of the retina
Axial myopiaAxial myopia - The eyeball is longer - The eyeball is longer than averagethan average
Curvature MyopiaCurvature Myopia – due to abnormal – due to abnormal curvature of the cornea curvature of the cornea (Keratoconus)(Keratoconus)
MYOPIA
Corrected by: Concave lenses
AstigmatismAstigmatism Abnormalities in corneal shapeAbnormalities in corneal shape
A condition wherein the light rays entering A condition wherein the light rays entering the eye focus on two or more separate the eye focus on two or more separate lines instead of one pointlines instead of one point
This happens when the refractive power is This happens when the refractive power is not uniform in all meridiansnot uniform in all meridians
Principal symptom: Principal symptom: inability to have clear inability to have clear imageimage
Usually accompanied by myopia or Usually accompanied by myopia or hyperopiahyperopia
TREATMENT: Cylindrical LensTREATMENT: Cylindrical Lens
TYPES OF REGULAR ASTIGMATISMTYPES OF REGULAR ASTIGMATISM
1. Compound myopic1. Compound myopicBoth anterior and posterior focal lines are in front of the
retina2. Simple Myopic2. Simple Myopic
Anterior focal line is in front of the retina while posterior focal line is on the retina
3. Mixed3. MixedAnterior focal line is in front of retina while posterior focal
line is at the back of the retina
4. Simple Hyperopic4. Simple HyperopicAnterior focal line is on the retina while posterior focal line
is behind the retina
5. Compound hyperopic5. Compound hyperopicBoth focal lines are behind the retina
1.1. Compound myopicCompound myopic
2. Simple Myopic2. Simple Myopic
3. Mixed3. Mixed
4. Simple Hyperopic4. Simple Hyperopic
5. Compound hyperopic5. Compound hyperopic
ERRORS OF REFRACTION 2ERRORS OF REFRACTION 2OO TO AGINGTO AGING
AccomodationAccomodation
- As object comes closer to the eye, lens As object comes closer to the eye, lens increases its power by altering its shape to increases its power by altering its shape to become more convexbecome more convex
- Accommodation = oculomotor nerve Accommodation = oculomotor nerve stimulation (parasympathetic fibers)stimulation (parasympathetic fibers)
PresbyopiaPresbyopia
- manifest in 5- manifest in 5thth decade decade
- overcome by convex lens (Reading - overcome by convex lens (Reading glasses)glasses)
PRESBYOPIAPRESBYOPIAloss of accommodation due to agingloss of accommodation due to aging
Inability to read small printInability to read small print
Due to a reduction in the deformability of the lensDue to a reduction in the deformability of the lens
Corrected by: Corrected by: convex lenses (reading glasses), convex lenses (reading glasses), bifocals or progressive lensesbifocals or progressive lenses
ERRORS OF REFRACTION 2ERRORS OF REFRACTION 2OO TO AGINGTO AGING
““Second Sight” – Myopic shiftSecond Sight” – Myopic shift
↑ ↑ density of lens nucleus (nuclear density of lens nucleus (nuclear sclerosis)sclerosis)
↑ ↑ refractive power → myopiarefractive power → myopia
distant vision → blurred and out of focusdistant vision → blurred and out of focus
near vision→ improvesnear vision→ improves
AnisometropiaAnisometropia
difference in refractive power difference in refractive power between the two eyesbetween the two eyes
major cause of amblyopia due to major cause of amblyopia due to failure of both eyes to failure of both eyes to accommodate independentlyaccommodate independently
cause complications in refractive cause complications in refractive correction due to:correction due to:
differences in size of retinal images differences in size of retinal images (aniseikonia)(aniseikonia)
CONGENITAL ERRORS OF CONGENITAL ERRORS OF REFRACTIONREFRACTION
Hyperopic at birth (+1.50 D)Hyperopic at birth (+1.50 D)
Corneal curvature is much steeper (6.59 mm Corneal curvature is much steeper (6.59 mm radius) at birth and flattens to adult curvature radius) at birth and flattens to adult curvature (7.71 mm) by about 1 y/o(7.71 mm) by about 1 y/o
Cornea and lens grow and eyes elongate with Cornea and lens grow and eyes elongate with child growth thus,child growth thus,
HYPEROPIA --> EMMETROPIA OR MYOPIAHYPEROPIA --> EMMETROPIA OR MYOPIA
IATROGENIC ERRORS IATROGENIC ERRORS OF REFRACTIONOF REFRACTION
Cataract Surgery:Cataract Surgery:
a. Tension in suture astigmatisma. Tension in suture astigmatism
Reduced by suture removalReduced by suture removal
Induced astigmatism may persistInduced astigmatism may persist
b. Removal of lensb. Removal of lens
Artificial lens replacementArtificial lens replacement
MEASUREMENT OF EORMEASUREMENT OF EOR
1. Subjective method1. Subjective method
- utilizes the ability of the individual to choose the lens that - utilizes the ability of the individual to choose the lens that gives him the best imagegives him the best image
- a set of trial lenses is usually used- a set of trial lenses is usually used
2. Objective method2. Objective method
Retinoscopy Retinoscopy •• makes use of an instrument (retinoscope) that catches makes use of an instrument (retinoscope) that catches the rays of light reflected at the patient’s retina whose the rays of light reflected at the patient’s retina whose source comes from a mirror near the examiner’s eyesource comes from a mirror near the examiner’s eye•• useful in children, the low intelligent, semiconscious or useful in children, the low intelligent, semiconscious or unconsciousunconscious
MEASUREMENT OF EORMEASUREMENT OF EOR
3. Cyclopegic Refraction3. Cyclopegic Refraction
drugs that paralyze accommodation are used to measure accurately the refractive error the individual has by the objective method
usually performed in children
4. Keratometry4. Keratometry measurement of the corneal astigmatism
the curvature of the cornea is measured in various meridians by reflected light on the cornea coming from
plates with various transparent configurations
CORRECTION OF EORCORRECTION OF EORSpectacle lensesSpectacle lenses
- safest method of refractive correction- safest method of refractive correction
- correct low degrees of ametropia- correct low degrees of ametropia
- bifocals: lens for both near and distant - bifocals: lens for both near and distant vision in single framevision in single frame
- progressive: graduated lens for objects - progressive: graduated lens for objects at any at any distancedistance
- may be cosmetically unacceptable for - may be cosmetically unacceptable for high degrees of ametropiahigh degrees of ametropia
Limitation of Limitation of Spectacles:Spectacles:
Most spectacles are worn successfully. Most spectacles are worn successfully. Problems occur with increasing refractive Problems occur with increasing refractive power.power.
Cosmesis : convex magnify,concave minifyCosmesis : convex magnify,concave minify
Distortion of objects in peripheral visionDistortion of objects in peripheral vision
Magnification of objects by highly convex Magnification of objects by highly convex lenseslenses
WeightWeight
Cannot correct severe astigmatismCannot correct severe astigmatism
Contact LensesContact Lenses
DISADVANTAGES:DISADVANTAGES: worn beneath the eyelids anterior to the cornea
May be hard or soft
Used to neutralize ametropia
To protect the healing cornea
To conceal unsightly damaged eyes
not appropriate for children
Maintenance
Size
Irritation
infection
TYPES OF CONTACT LENSES:TYPES OF CONTACT LENSES:
1. Hard contact lenses1. Hard contact lenses
Offer clear, crisp vision and are durable
Correct major errors of refraction
Indicated for correction of irregular
astigmatism
Correct by changing the curvature of the
anterior surface of the eye
2. Soft contact lenses2. Soft contact lenses
More comfortable
Require little adjustment to their use
Easier to insert and remove than hard lenses
little correction of astigmatism
Provide poorer corrected vision than do hard lenses
Contact Lens CareContact Lens Care
Do not exceed the recommended Do not exceed the recommended wearing timewearing timeObserve meticulous hygieneObserve meticulous hygieneDo not clean with tap water or salivaDo not clean with tap water or salivaRemove if the eye becomes sore or Remove if the eye becomes sore or inflammedinflammedRemove soft lenses while Remove soft lenses while administering preservative administering preservative containing dropscontaining drops
Complications of Contact Lens use
Giant papillary conjunctivitis – a condition in which wearers of (usually) soft contact lenses develop increasing ocular discomfort and itching
Corneal vascularization - more common in soft lens due to larger surface area covering the part of the sclera and limbus
Corneal ulceration
Corneal infection
CORRECTION FOR EORCORRECTION FOR EOR
Keratorefractive SurgeryKeratorefractive Surgery
Radial KeratotomyRadial Keratotomy
Photorefractive Keratectomy (PRK)Photorefractive Keratectomy (PRK)
Laser Assisted Intrastromal Laser Assisted Intrastromal Keratomileusis (LASIK)Keratomileusis (LASIK)
Keratorefractive Keratorefractive surgerysurgery
Radial keratotomyRadial keratotomy
incisional technique incisional technique to alter corneal to alter corneal curvaturecurvature
Cornea becomes Cornea becomes flatter as incision flatter as incision healsheals
Excimer laserExcimer laser: shaves off ultra-thin : shaves off ultra-thin discs of corneal tissue to reduce discs of corneal tissue to reduce refractive power in myopiarefractive power in myopia
PRK (photorefractive PRK (photorefractive keratectomy)keratectomy)
LASIK (laser assisted in-situ LASIK (laser assisted in-situ keratomileusis)keratomileusis)
Photorefractive Keratectomy Photorefractive Keratectomy (Excimer laser)(Excimer laser)
Uses an excimer laser to reshape the Uses an excimer laser to reshape the outer surface of the corneaouter surface of the cornea
Benefits:Benefits:
- reliable correction of low to moderate - reliable correction of low to moderate myopia (-2 to -6 diopters)myopia (-2 to -6 diopters)
- improvement in unaided visual acuity- improvement in unaided visual acuity
Complications:Complications: - corneal haze- corneal haze - post op pain- post op pain - loss of best-corrected visual acuity- loss of best-corrected visual acuity - regression of effect- regression of effect
LASIKLASIKcorneal flap is created --- Excimer laser corneal flap is created --- Excimer laser reshapes the corneareshapes the cornea
reliable correction of low to high myopia (-2 to reliable correction of low to high myopia (-2 to -12 diopters)-12 diopters)
BenefitsBenefits
Clear vision in 24 hoursClear vision in 24 hours
Minimal post-op painMinimal post-op pain
LimitationLimitation
Additional surgical stepAdditional surgical step
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CORRECTION OF CORRECTION OF EOREOR
Intraocular lenses- phakic IOLsIntraocular lenses- phakic IOLs
Clear lens extraction for myopiaClear lens extraction for myopia
- extraction of non-cataractous lenses- extraction of non-cataractous lenses
- eyes must be highly myopic in order for - eyes must be highly myopic in order for the operation to be a success.the operation to be a success.
LensLens
LensLenstransparent, transparent, avascular, biconvexavascular, biconvex
Held in position by Held in position by zonules zonules
Surrounded by the Surrounded by the lens capsulelens capsule
1 of the main 1 of the main refracting surfaces of refracting surfaces of the eyethe eye
Has inherent Has inherent elasticityelasticity
LensLensCross sectionCross section
Causes of CataractCauses of CataractAge relatedAge related
50 % in 65 – 74 yo50 % in 65 – 74 yo
70 % in > 75 yo70 % in > 75 yo
3 main types3 main types
Subcapsular Subcapsular CataractCataract
Nuclear CataractNuclear Cataract
Cortical CataractCortical Cataract
CataractCataract
Subcapsular cataractSubcapsular cataract
May be anterior or posteriorMay be anterior or posterior
Anterior type is associated with Anterior type is associated with fibrous metaplasia of the fibrous metaplasia of the anterior epithelium of the lensanterior epithelium of the lens
Posterior type is associated Posterior type is associated with posterior migration of the with posterior migration of the epithelial cells of the lensepithelial cells of the lens
CataractCataractNuclear CataractNuclear Cataract
Sclerosis and yellowing of the lens Sclerosis and yellowing of the lens nucleusnucleus
Myopic shift “second sight”Myopic shift “second sight”
Advanced cases, nucleus becomes Advanced cases, nucleus becomes opaque and brown (brunescent opaque and brown (brunescent nuclear cataract)nuclear cataract)
CataractCataractCortical cataractCortical cataract
Hydropic swelling of the lens fibersHydropic swelling of the lens fibers
Due to ionic changes in the lens fibersDue to ionic changes in the lens fibers
Formation of radial cortical spokes.Formation of radial cortical spokes.
Mature CataractMature Cataract – Entire cortex becomes – Entire cortex becomes opaqueopaque
Hypermature CataractHypermature Cataract – Leakage of – Leakage of degenerated cortical material through the degenerated cortical material through the lens capsule leaving the capsule wrinkled and lens capsule leaving the capsule wrinkled and shrunken.shrunken.
Morgagnian CataractMorgagnian Cataract – further liquefaction of – further liquefaction of the cortex allows free movement of the the cortex allows free movement of the nucleusnucleus
CataractCataractMature Cortical CataractMature Cortical Cataract
CataractCataractHypermature CataractHypermature Cataract
CataractCataractMorgagnian CataractMorgagnian Cataract
Traumatic CataractTraumatic CataractDirect Penetrating Injury - Direct Penetrating Injury - lens capsule ruptured lens capsule ruptured with hydration of lens fiberswith hydration of lens fibers
Blunt injuryBlunt injury
stellate or rosette shaped opacificationstellate or rosette shaped opacification
Vossius ring – imprinting of iris pigment onto Vossius ring – imprinting of iris pigment onto the anterior lens capsulethe anterior lens capsule
Electric shockElectric shock – causes protein coagulation and – causes protein coagulation and cataract formationcataract formation
Ionizing radiation Ionizing radiation - damage to actively growing - damage to actively growing lens cells, younger patients more susceptiblelens cells, younger patients more susceptible
Traumatic CataractTraumatic CataractSevere penetrating traumaSevere penetrating trauma
Traumatic cataractTraumatic cataractVossius ringVossius ring
Metabolic CataractMetabolic CataractDiabetes MellitusDiabetes Mellitus
Inc. glucose in aqueous humor
Glucose enters lens by diffusion
Glucose converted to sorbitol
Influx of water in the lens
“Snow flake” Cataract
Metabolic CataractMetabolic CataractGalactosemiaGalactosemia
Autosomal recessiveAutosomal recessive
Inability to convert galactose to glucoseInability to convert galactose to glucose
Symptoms of Malnutririon,hepatomegaly, Symptoms of Malnutririon,hepatomegaly, jaundice and mental deficiencyjaundice and mental deficiency
75 % develops cataract few weeks after birth75 % develops cataract few weeks after birth
Inc. galactose and glactiol in the lens cellsInc. galactose and glactiol in the lens cells
Nucleus and deep cortex opacifiedNucleus and deep cortex opacified
““Oil dropletOil droplet” cataract” cataract
Metabolic CataractMetabolic Cataract
Wilson’s diseaseWilson’s disease
Autosomal recessiveAutosomal recessive
Disorder in copper metabolismDisorder in copper metabolism
Cuprous oxide (reddish brown pigment) Cuprous oxide (reddish brown pigment) is deposited in the anterior lens capsuleis deposited in the anterior lens capsule
““sunflower cataractsunflower cataract””
Toxic CataractToxic CataractSteroid induced cataractSteroid induced cataract
Posterior subcapsular cataractPosterior subcapsular cataract
PhenothiazinesPhenothiazines
Yellow brown granules on the anterior capsuleYellow brown granules on the anterior capsule
Visually insignificantVisually insignificant
Miotics - cholinesterase inhibitorsMiotics - cholinesterase inhibitors
Anterior subcapsular vacuolesAnterior subcapsular vacuoles
Amiodarone Amiodarone
anterior subcapsular lens opacitiesanterior subcapsular lens opacities
Visually InsignificantVisually Insignificant
Secondary CataractSecondary Cataract
Chronic Anterior UveitisChronic Anterior Uveitis
Most common cause of secondary cataractMost common cause of secondary cataract
Formation of posterior synechiaeFormation of posterior synechiae
Thickening of anterior lens capsuleThickening of anterior lens capsule
Formation of fibrovascular membraneFormation of fibrovascular membrane
Chronic Anterior Uveitis
Secondary CataractSecondary CataractAcute angle closure glaucomaAcute angle closure glaucoma
glaukomfleckenglaukomflecken
Congenital Cataract
lens opacity present at birth
Rubella
Maternal infection with rubella virus
Cardiac defects, deafness, mental retardation
Cataracts are characterized by pearly white nuclear opacification
Abnormalities of Lens Shape Abnormalities of Lens Shape and Positionand Position
Coloboma-congenital absence of an eye Coloboma-congenital absence of an eye structurestructure
Lenticonus-cone formation in the anterior Lenticonus-cone formation in the anterior or posterior pole of the lensor posterior pole of the lens
Microphakia-lens with a smaller than Microphakia-lens with a smaller than normal diameternormal diameter
Microsherophakia-not only small but Microsherophakia-not only small but sphericalspherical
Ectopia LentisEctopia LentisMarfan Syndrome’sMarfan Syndrome’s
Widespread abnormality of connective tissue
Autosomal Dominant
Cardiac anomalies - aneurysm of the ascending aorta.
Skeletal anomalies – limbs are inappropriately long.
Arachnodactyly - excessively long fingers
Muscular underdevelopment
Zonular attachment of the lens usually are intact but become stretched and elongated
Marfan’s SyndromeMarfan’s Syndrome
Marfan’s SyndromeMarfan’s SyndromeOcular featureOcular feature
Bilateral lens subluxation – 80 % of Bilateral lens subluxation – 80 % of casescases
Ectopia Lentis
HomocystinuriaAutosomal recessive
Error of methionine metabolism
Lenses are usually subluxated inferiorly
Zoules have high levels of cysteine and tend to be brittle
Management of Management of CataractCataract
Cataract SurgeryCataract Surgery
Intracapsular Cataract SurgeryIntracapsular Cataract Surgery
Extracapsular Cataract SurgeryExtracapsular Cataract Surgery
PhacoemulsificationPhacoemulsification
Extracapsular Cataract Extracapsular Cataract ExtractionExtraction
PhacoemulsificationPhacoemulsification
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After CataractAfter Cataract
YAG laser capsulotomy
Complications of Cataract Complications of Cataract SurgerySurgery
EarlyEarly
Inc intraocular pressureInc intraocular pressure
Iris prolapseIris prolapse
Wound leakWound leak
Acute Bacterial EndophthalmitisAcute Bacterial Endophthalmitis
Pupil BlockPupil Block
Iris ProlapseIris Prolapse
Wound LeakWound Leak
Bacterial Bacterial EndophthalmitisEndophthalmitis
Complications of Cataract Complications of Cataract SurgerySurgery
LateLate
Toxic suture syndromeToxic suture syndrome
Corneal DecompensationCorneal Decompensation
Irvine-Gass SyndromeIrvine-Gass Syndrome
Toxic Suture Toxic Suture SyndromeSyndrome
Corneal Corneal DecompensationDecompensation
Irvine-Gass SyndromeIrvine-Gass Syndrome
Cystoid Cystoid macular edemamacular edema
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