obrazec za opis predmeta slo/eng progami... · aparati za ekstrakcijo tekočih zmesi. hitrost...

1

Termodifuzijska tehnika

UČNI NAČRT PREDMETA / COURSE SYLLABUS

Predmet: Termodifuzijska tehnika

Course title: Stagewise Processes

Študijski program in stopnja Study programme and level

Študijska smer Study field

Letnik Academic year

Semester Semester

Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level

1. zimski

Autumn

Vrsta predmeta / Course type: Obvezni / Obligatory

Univerzitetna koda predmeta / University course code:

Predavanja Lectures

Seminar Seminar

Sem. vaje Tutorial

Lab. vaje Laboratory

work

Teren. vaje Field work

Samost. delo Individ. work

ECTS

60 50 160 9

Nosilec predmeta / Lecturer: Željko Knez

Jeziki / Languages:

Predavanja / Lectures: slovenski / Slovene

Vaje / Tutorial: slovenski / Slovene

Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti:

Prerequisits:

Osvojeni pojmi in osnovna znanja s področij fizike, fizikalne kemije, termodinamike in prenosnih pojavov.

Basic knowledge of physics, physical chemistry, thermodynamics and transport phenomena.

Vsebina: Content (Syllabus outline):

Uparjanje. Procesni parametri. Tipi uparjalnikov. Postopki uparjanja. Dimenzioniranje uparjalnikov.

Kristalizacija. Osnove kristalizacije. Ravnotežje pri kristalizaciji. Hitrost tvorbe kristalnih jeder in rasti kristalov. Dimenzioniranje kristalizatorjev.

Destilacija. Ravnotežje pri destilaciji. Vrste destilacij. Rektifikacija. Vrste rektifikacij. Rektifikacijske naprave. Dimenzioniranje kolon.

Ekstrakcija trdno-tekoče. Hitrost ekstrakcije. Prenos snovi pri ekstrakciji trdnih snovi. Vrste ekstraktorjev. Dimenzioniranje ekstrakcijske baterije.

Ekstrakcija tekočih zmesi. Osnove. Postopki ekstrakcije tekoče-tekoče. Aparati za ekstrakcijo tekočih zmesi. Hitrost ekstrakcije.

Evaporation. Process parameters. Types of evaporators. Processes of evaporation. Design of evaporators.

Crystallization. Fundamentals of crystallization. Equilibrium in crystallization. The rate of crystal core formation and crystal growth. Design of crystallizators.

Distillation. Equilibrium in a distillation. Distillation types. Rectification. Rectification types. Rectification apparatus. Design of column.

Solid-liquid extraction. Extraction rate. Mass transfer in solid extraction. Extractor types. Design of extraction battery.

Extraction of liquid mixtures. Fundamentals. Processes of liquid-liquid extractions. Extraction apparatus for liquid mixtures. Extraction rate.

2

Dimenzioniranje protitočne ekstrakcijske baterije.

Tehnologije s fluidi nad kritično točko Ekstrakcijski procesi s superkritičnimi fluidi. Biokemijske reakcije v superkritičnih fluidih. Uporaba superkritičnih fluidov za mikronizacijo.

Sušenje. Namen in potek sušenja. Metode sušenja. Osnove psihrometrije. Mehanizem sušenja s hlapljenjem. Vrste sušilnikov. Dimenzioniranje sušilnikov.

Laboratorijske vaje: V okviru laboratorijskih vaj se izvaja tankoslojno uparjanje, diferencialna destilacija, rektifikacija, ekstrakcija trdno-tekoče, in sušenje.

Design of counter current extraction battery.

Technologies with fluids above critical point. Extraction processes with supercritical fluids Biochemical reactions in supercritical fluids. Application of supercritical fluids for micronization.

Drying. Purpose and procedure of drying. Drying methods. Fundamentals of psihrometry. The mechanism of drying with evaporation. Dryer types.

Laboratory work: Laboratory work includes thin-layer evaporation, differential distillation, rectification, solid-liquid extraction, and drying.

Temeljni literatura in viri / Readings:

Ž. Knez, M. Škerget, Termodifuzijski separacijski procesi, FKKT, Maribor, 2009.

Dodatna priporočena literatura:

K. Sattler, H. J. Feindt, Thermal Separation Processes: Principles and Design, VCH, Weinheim, 2007.

Paul T. Anastas, Carlos A. M. Afonso, João Pedro G. Crespo, Green Separation Processes: Fundamentals and Applications, VCH, Weinheim, 2005.

V. Anikeev, M. Fan, Supercritical Fluid Technology for Energy and Environmental Applications, Elsevier, 2014.

Cilji in kompetence: Objectives and competences:

Predmet sodi med osnovne kemijsko inženirske predmete. Kot sinteza kemijske in inženirske termodinamike, transportnih fenomenov ter masnih in toplotnih bilanc zagotovi osnovno znanje, ki ga inženir-tehnolog potrebuje pri vodenju in načrtovanju separacijskih procesov ter naprav. Predmet razvija študentu sposobnost analize in sinteze kompleksnih kemijsko tehnoloških sistemov.

The subject is one of the fundamental subjects in Chemical engineering. As synthesis of chemical and engineering thermodynamics, transport phenomena, as well as mass and heat balance, it assures the basic knowledge for an engineer-technologist, which is needed in control and design of separation processes and apparatus. The subject develops the student ability of analysis and synthesis of complex chemical technological systems.

Predvideni študijski rezultati:

Intended learning outcomes:

Znanje in razumevanje: Zmožnost načrtovanja destilacijskega, uprajalnega ali ekstrakcijskega sistema. Uporaba ustreznih procesnih parametrov v povezavi z načrtovanim sistemom.

Knowledge and understanding: Design of distillation, evaporation or extraction system. Application of proper process parameters for a defined process analysis.

Prenesljive/ključne spretnosti in drugi atributi: Vsebina predmeta je povezana z ostalimi predmeti na smeri Kemijska tehnika in podaja znanja, potrebna za razumevanje vsebin, ki so zajeta npr. pri predmetu Bioseparacijska tehnika in biokataliza.

Transferable/Key Skills and other attributes: The subject is connected to other subjects on the direction Chemical engineering and gives the knowledge which is necessary for understanding other subjects such as Bioseparation engineering and biocatalysis.

Metode poučevanja in učenja: Learning and teaching methods:

- predavanja - laboratorijske vaje

- lectures - laboratory work

3

Načini ocenjevanja:

Delež (v %) / Weight (in %)

Assessment:

Način (pisni izpit, ustno izpraševanje, naloge, projekt) Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti:

pisni izpit

ustni izpit

laboratorijske vaje

60 30 10

Type (examination, oral, coursework, project): Student has to pass successfully the following obligations:

written examination

oral examination

laboratory work

Reference nosilca / Lecturer’s references:

KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010, str. [3]-38.

REIBE, Christian, KNEZ, Željko, WEIDNER, Eckhard. A new high-pressure micronisation process for the gentle processing of high molecular mass gelatine. Food and bioproducts processing, ISSN 0960-3085, 2012, vol. 90, no. 2, str. 79-86, doi: 10.1016/j.fbp.2011.02.001.

KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca. Industrial applications of supercritical fluids : a review. Energy, ISSN 0360-5442, 2014, str. 1-9, doi: 10.1016/j.energy.2014.07.044.

KNEZ, Željko, MARKOČIČ, Elena, KNEZ HRNČIČ, Maša, RAVBER, Matej, ŠKERGET, Mojca. High pressure water reforming of biomass for energy and chemicals : a short review. The Journal of supercritical fluids, ISSN 0896-8446, 2014, vol. , str. 1-8, doi: 10.1016/j.supflu.2014.06.008.

RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from sunflower seeds with subcritical water. Food chemistry, ISSN 0308-8146, 2015, vol. 166, str. 316-323, doi: 10.1016/j.foodchem.2014.06.025.

4

Načrtovanje procesov


Predmet: Načrtovanje procesov

Course title: Process Design




Semester Semester


1. zimski

Autumn



Predavanja

Lectures Seminar Seminar

Sem. vaje Tutorial

Lab. vaje Labor work



ECTS

45 30 105 6

Nosilec predmeta / Lecturer: Zorka Novak Pintarič

Jeziki: Languages:

Predavanja / Lecture: slovenski / Slovene



Prerequisites:

Potrebno je znanje iz termodinamike, prenosa toplote in snovi ter osnovno znanje iz separacijske in reakcijske tehnike.

Knowledge about thermodynamics, heat and mass transfer and basic knowledge about separation and reaction engineering is required.

Vsebina:

Content (Syllabus outline):

Strategije načrtovanja in integracije kemijskih procesov (hierarhična, termodinamska, algoritemska). Modeli za oceno termofizikalnih lastnosti v simulatorjih. Načrtovanje in simulacija procesnih podsistemov:

- reakcijske poti, reaktorji in reaktorska omrežja, - separatorji in separacijska omrežja. - omrežje reaktor-separator-obtok.

Procesna integracija: - integrirana omrežja toplotnih prenosnikov, - toplotna integracija reaktorjev, separatorjev in

separacijskih omrežij, - toplotni stroji in toplotne črpalke, - vpliv toplotne integracije na obtok in celotno

presnovo reaktantov, - vodna integracija.

Načrtovanje šaržnih procesov. Načrtovanje integriranih, trajnostnih procesov.

Strategies for chemical process design and integration (hierarchic, thermodynamic, algorithmic). Models for thermophysical property data in process simulators. Design and simulation of process subsystems:

- reaction paths, reactors and reactor networks, - separators and separation sequencing, - reactor-separator-recycle networks.

Process integration: - heat exchanger networks, - heat integration of reactors, separators and

separation networks, - heat engines and heat pumps, - interactions of heat integration, purge-to-recycle

ratio and overall conversion of reactants, - water integration.

Design of batch processes. Design of integrated sustainable processes.

5

Sprotno reševanje domačih nalog. Računalniške vaje: Simulacije posameznih procesnih enot in procesnih podsistemov. Projektno delo z izdelavo projektnega poročila (proizvodnja specifične kemikalije, lastnosti in uporaba produkta, pregled tehnologij, varnost in okolje, cene, procesna shema).

Ongoing homework assignments. Computer Exercises: Simulation of process equipment and process subsystems. Project work including written report (production of specific chemical product, properties and use of product, overview of technologies, safety and environment, prices, process flow sheet).

Temeljni literatura in viri / Textbooks:

Z. Novak Pintarič, Načrtovanje in integracija procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014.

Z. Novak Pintarič, Simulacija kemijskih procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014.


R. Smith, Chemical Process Design and Integration, J. Wiley, 2005.

W. D. Seider, J. D. Seader, D. R. Lewin: Product and process design principles: synthesis, analysis, and evaluation. Second Edition, Wiley, New York, 2004.

J. J. Klemeš (Ed.), Handbook of Process Integration (PI), Woodhead Publishing, Cambridge, 2013.

Cilji in kompetence:

Objectives and competences:

Študent spozna konceptualno načrtovanje kemijskih procesov, osvoji osnove procesno sistemskega pristopa in integracije procesov s poudarkom na hierarhičnih in termodinamskih metodah.

To acquaint students with conceptual design of chemical processes. To acquire process system engineering approach to process design and integration, based on hierarchic and thermodynamic methods.



Znanje in razumevanje: Študent bo sposoben: - Uporabiti ustrezne metode in računalniške

programe za simulacijo in integracijo kemijskih procesov.

- Analizirati povezave med podsistemi: reakcija-separacija-obtok-toplotna integracija.

- Analizirati vplive toplotne integracije, obtoka in razmerja odtok/obtok na celotno presnovo reaktantov.

- Integrirati toplotne tokove v procesu in skonstruirati omrežje toplotnih prenosnikov.

- Integrirati vodne operacije v procesu in skonstruirati integrirano vodno omrežje.

- Načrtovati kontinuirne in šaržne kemijske procese na konceptualnem nivoju.

Knowledge and Understanding: Student will be able to: - Use appropriate methods and computer programs

for simulation and integration of chemical processes.

- Analyse interactions among subsystems: reaction-separation-recycle-heat integration.

- Analyse trade-offs between heat integration, recycle, purge to recycle ratio, and overall conversion of reactants.

- Integrate process heat streams and construct heat exchanger network.

- Integrate process water operations and construct integrated water network.

- Design continuous and batch processes on conceptual level.

Prenesljive/ključne spretnosti in drugi atributi: Računalniško načrtovanje reaktorjev, separatorjev, toplotnih strojev in črpalk, celotnih procesnih shem. Razvijanje sposobnosti za skupinsko in projektno delo.

Transferable/key skills and other attributes: Computer aided design and retrofit of reactors, separators, heat engines, heat pumps, and process flow sheets. Abilities to work in team. Experience in executing large projects.

6


Aktivno poučevanje in učenje. Individualne računalniške vaje. Uporaba tujih jezikov in literature. Skupinske računalniške vaje simuliranja, integriranja, načrtovanja. Pisanje in zagovor poročil iz posamičnih vaj in skupinskega projektnega poročila.

Active teaching and learning. Individual work using computers. Usage of foreign languages and literature. Team-work in process design, simulation and integration. Writing and defence of individual work as well as the team design report.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni računski izpit ali dva računska

testa izpit teorije ali dva testa teorije projektno poročilo domače naloge

Računski test in test teorije se izvajata hkrati. Vse domače naloge morajo biti rešene.

60

20 15 5

Student has to pass successfully the following obligations:

written exam (calculus) or two written tests (calculus)

Theory exam or two theory tests

project report

homeworks Calculus test and theory test are performed simultaneously. All homework assignments must be completed.


NOVAK-PINTARIČ, Zorka, KRAVANJA, Zdravko. Suitable process modelling for proper multi-objective optimization of process flow sheets. V: KLEMEŠ, Jiri (ur.), VARBANOV, Petar (ur.), LIEW, Peng Yen (ur.). 24th European Symposium on Computer Aided Process Engineering : [ESCAPE-24, 15 to 18 June 2014, Budapest, Hungary], (Computer aided chemical engineering, ISSN 1570-7946, 33). Amsterdam ... [et al.]: Elsevier, cop. 2014, str. 1388-1392. [COBISS.SI-ID 18172438]

NOVAK-PINTARIČ, Zorka, KASAŠ, Mihael, KRAVANJA, Zdravko. Sensitivity analyses for scenario reduction in flexible flow sheet design with a large number of uncertain parameters. AIChE journal, ISSN 0001-1541. [Print ed.], Avg. 2013, vol. 59, iss. 8, str. 2862-2871, doi: 10.1002/aic.14061. [COBISS.SI-ID 16795926]

TOKOS, Hella, NOVAK-PINTARIČ, Zorka, GLAVIČ, Peter. Energy saving opportunities in heat integrated beverage plant retrofit. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2010, vol. 30, no. 1, str. 36-44, doi: 10.1016/j.applthermaleng.2009.03.008. [COBISS.SI-ID 13122838]

TOKOS, Hella, NOVAK-PINTARIČ, Zorka. Synthesis of batch water network for a brewery plant. Journal of cleaner production, ISSN 0959-6526. [Print ed.], Nov. 2009, vol. 17, iss. 16, str. 1465-1479, doi: 10.1016/j.jclepro.2009.06.009. [COBISS.SI-ID 13317910]

NOVAK-PINTARIČ, Zorka. Načrtovanje in integracija procesov : zbrano gradivo za predmet Načrtovanje procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [145] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21344, http://dkum.uni-mb.si/IzpisGradiva.php?id=44461. [COBISS.SI-ID 17583638]

NOVAK-PINTARIČ, Zorka. Simulacija kemijskih procesov : zbrano gradivo za vaje pri predmetu Načrtovanje procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [37] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21375, http://dkum.uni-mb.si/IzpisGradiva.php?id=44466. [COBISS.SI-ID 17583894]

7

Kemijska reakcijska tehnika II


Predmet: Kemijska reakcijska tehnika II

Course title: Chemical Reaction Engineering II




Semester Semester


1. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

45 30 105 6

Nosilec predmeta / Lecturer: Andreja Goršek

Jeziki / Languages:




Prerequisites:

Potrebno je znanje iz materialov, termodinamike, prenosa toplote in snovi ter osnovno znanje iz separacijske in kemijske reakcijske tehnike.

Knowledge about materials engineering, thermodynamics, heat and mass transfer and basic knowledge about separation and reaction engineering is required.

Vsebina:


Predavanja: Heterogeni reakcijski sistemi. Bifluidne in fluosolidne reakcije. Katalizirane reakcije. Temperaturni učinki pri homogenih reakcijah in v stopenjskih reaktorjih z nasuto plastjo. Upor v porah katalizatorja in toplotni učinki. Reaktor s fluidizirano plastjo. Dezaktivirna kataliza. Biokemijski reakcijski sistemi. Načrtovanje reaktorjev (osnove, simulacija procesnih operacij, modeliranje reaktorjev). Izbira materialov (termodinamika in kinetika plinske in elektrolitske korozije, protikorozijska zaščita, pojavne oblike korozije).

Lectures: Heterogeneous reaction systems. Fluid-fluid and fluid-particle reactions. Solid catalyzed reactions. Temperature effects in homogeneous and packed-bed reactors. Catalyst pore resistance, heat effects. Fluidised bed reactor. Deactivating catalysis. Biochemical reaction systems. Reactor design (simulation of process operations, reactor modelling). Material selection (thermodynamics and kinetics of gaseous/electrolytic corrosion, corrosion prevention, and forms of corrosion).

8

Računalniške vaje: Modeliranje reaktorjev (mešalni, kaskadni, cevni), kinetika radikalov, heterogena kataliza, kopolimerizacija, porazdelitve bivalnih časov, dinamično modeliranje). Laboratorijske vaje: Korozijska odpornost gradiv Katalitski reaktor

Computer Exercises: Reactor modelling (mixed flow, in series, plug flow), kinetics of radicals, heterogeneous catalysis, copolymerization, residence time distribution, dynamic modelling. Laboratory Exercises: Corosion resistance of materials Catalytic reactor


P. Glavič, Kemijska reakcijska tehnika, zbirka nalog z navodili in rešitvami, UM FKKT, Maribor, 2007.

O. Levenspiel, Chemical Reaction Engineering, 3rd Ed., John Wiley and Sons, New York, 1999.


P. Glavič, Gradiva, UM, FKKT, Maribor, 2006.

H. Scott Fogler, Elements of Chemical Reaction Engineering, Prentice-Hall, London, 2005.



Študent se seznani s heterogenimi reakcijskimi sistemi. Dodatno spozna numerično modeliranje in načrtovanje kataliziranih in nekataliziranih reakcijskih sistemov, zahtevnejše vrste reaktorjev in toplotne učinke v njih. Izbira in uporaba gradiv v konstruiranju. Propadanje gradiv in obvladovanje hitrosti korozije. Sinteza znanj iz kemije, termodinamike, osnovnih pojavov in operacij, varnosti in okolja, ekonomike.

Student is introduced to heterogeneous reaction systems together with modelling of catalytic and non-catalytic reaction systems, more complex reactors and their heat effects. Selection and use of construction materials. Corrosion and corrosion prevention in materials. Synthesis of knowledge, acquired in: chemistry, basic phenomena, thermodynamics, unit operations, safety, environmental protection, economics.



Znanje in razumevanje: Razširitev znanja na kompleksne reakcijske sisteme (več vzporednih, zaporednih, ravnotežnih, kataliziranih reakcij), za katere so značilni komplicirani izrazi za proizvodnost in posebni načini kontaktiranja.

Knowledge and Understanding: Knowledge extension to complex reaction systems (more parallel, series, equilibrium, and catalyzed reactions) with more complicated rate expressions and contacting patterns.

Prenesljive/ključne spretnosti in drugi atributi: Razumevanje heterogenih reakcij, pravilna izbira reaktorjev in modeliranje osnovnih ter zahtevnejših tipov reaktorjev (prav tako osnovnih operacij).

Transferable/key skills and other attributes: Understanding of heterogeneous reactions, choice of right reactor and modelling of simple and more complex reactors (basic unit operations).

Metode poučevanja in učenja:

Learning and teaching methods:

Aktivno poučevanje in učenje. Individualne računalniške vaje. Uporaba tujih jezikov in literature. Računalniške vaje modeliranja. Laboratorijske vaje. Pisanje in zagovor poročil iz posamičnih vaj.

Active teaching and learning. Individual work using computers. Usage of foreign languages and literature. Computer exercises on modelling. Laboratory exercises. Writing and defence of individual work.

9



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - računalniške vaje - laboratorijske vaje - pisni izpit - ustni izpit

20 10 40 30

Student has to pass successfully the following obligations: - computer exercises - laboratory - writen exam (problem solving) - oral exam


KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN 1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249, ilustr., doi: 10.2478/s11532-013-0373-6. [COBISS.SI-ID 17373718].

PEČAR, Darja, GORŠEK, Andreja. Oxidation of menthol : reaction-rate determination based on thermodynamic profiles. Chemical engineering communications, ISSN 0098-6445, 2014, vol. 201, iss. 11, str. 1548-1554. http://www.tandfonline.com/doi/full/10.1080/00986445.2013.819353#.U6E-jU-KDq4. [COBISS.SI-ID 17918998].

ZAJŠEK, Katja, GORŠEK, Andreja, KOLAR, Mitja. Cultivating conditions effects on kefiran production by the mixed culture of lactic acid bacteria imbedded within kefir grains. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2013, vol. 139, iss. 1-4, str. 970-977, doi: 10.1016/j.foodchem.2012.11.142. [COBISS.SI-ID 16645142].

GORŠEK, Andreja, TRAMŠEK, Marko. Production of unique naturally immobilized starter : a fractional factorial design approach towards the bioprocess parameters evaluation. V: MATOVIC, Darko (ur.). Biomass - detection, production and usage. Rijeka: InTech, cop. 2011, str. 185-200. http://www.intechopen. com/source/pdfs/19074/InTech-Production_of_unique_naturally_immobilized_starter_a_fractional_factorial_design_approach_towards_the_bioproces s_parameters_evaluation.pdf. [COBISS.SI-ID 15454998].

LEŠER, Tadej, GORŠEK, Andreja. Study of enamel frit melting kinetics. Glass technology, ISSN 0017-1050, Oct. 2013, vol. 54, no. 5, str. 199-203. [COBISS.SI-ID 17385238].

10

Dinamika in optimiranje procesov


Predmet: Dinamika in optimiranje procesov

Course title: Process Dynamics and Optimization




Semester Semester


1. zimski

autumn



Predavanja


Sem. vaje Tutorial




ECTS

60 45 165 9

Nosilec predmeta / Lecturer: Zdravko Kravanja

Jeziki / Languages:




Prerequisites:

Osnove dinamike procesov, linearnega (LP) in nelinearnega programiranja (NLP).

Basic knowledge of process dynamics, linear (LP) and nonlinear programming (NLP).

Vsebina:


Matematično modeliranje in reševanje: dinamično modeliranje nekaterih osnovnih procesnih operacij, numerična integracija in reševanje diferencialno-algebrskih sistemov enačb, dinamična simulacija.

Dinamika procesov:

Uvod in načrtovanje sistemov z eno spremenljivko: povratnozančna regulacija in frekvenčna analiza, sistemi z velikim mrtvim časom in inverznim odzivom, večzančne strukture, vnaprejšnja in razmerna regulacija, adaptivna in inferenčna regulacija.

Načrtovanje sistemov z več spremenljivkami: alternativne regulcijske konfiguracije, medzančne interakcije in ukrepi, osnove načrtovanja regulacijskih sistemov za celotne obrate.

Osnove načrtovanja računalniških regulacijskih sistemov in optimiranja v realnem času.

Optimiranje in integracija procesov:

Mathematical modeling and solution: dynamic modeling of some basic process unit operations, numerical integration and solution of differential-algebraic systems of equations, dynamic simulation.

Process Dynamics:

Introduction and design of single variable control systems (SISO): feedback control and analysis of frequency response, systems with large dead time or inverse response, multiple loop configurations, feedforward control and ratio control, adaptive and inferential control.

Multivariable control systems (MIMO): alternative control configurations, interaction of control loops, relative-gain array and decoupling of the loops, basic aspects in designing a control system for overall plant.

Basic aspects in designing computer control systems and on-line optimization.

11

Uvod, namenska funkcija in optimizacijski kriteriji v procesnih industrijah.

Diskretno in zvezno optimiranje: mešano-celoštevilsko linearno programiranje (MILP) in algoritem vejanja in omejevanja, mešano-celoštevilsko nelinearno programiranje (MINLP) in algoritem zunanje poenostavitve.

Optimalno načrtovanje/sinteza toplotno integriranih omrežij toplotnih prenosnikov s sekvenčnim in simultanim pristopom.

Optimiranje procesnih shem: SQP – zaporedno kvadratično programiranje, optimiranje s procesnimi simulatorji, optimiranje z enačbnimi sistemi.

Načrtovanje in optimiranje saržnih procesov. Računalniške vaje: dinamične simulacije in optimiranje.

Process optimization and integration:

Introduction, objective function and optimization criteria in process industries.

Discrete and continuous optimization: mixed-integer linear programming (MILP) and branch-and-bound algorithm, mixed-integer nonlinear programming (MINLP) and outer-approximation algorithm.

Optimal design/synthesis of heat integrated heat exchanger networks with sequential and simultaneous approach.

Process flowsheet optimization: SQP – successive quadratic programming, optimization with process simulators, and optimization with equation oriented systems.

Design and optimization of batch processes. Computer room: dynamic simulation and optimization.


Zdravko Kravanja: Dinamika procesov, Zapiski predavanj. Zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2009.

Zdravko Kravanja in Zorka Novak Pintarič: Optimiranje procesov, Zapiski predavanj. Zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2006.


Seborg, D. E., T. F. Edgar in D. A. Mellichamp, Process Dynamics and Control (2nd ed.), John Wiley & Sons, New York, 2004.

Ravidran A., K. M. Ragsdell in G. V. Reklaitis, Engineering Optimization, Methods and Application (2nd ed.), John Wiley and Sons, New York, 2006.

Biegler L. T., I. E.Grossmann and A. W.Westerberg, Systematic Methods of Chemical Process Design, Prentice Hall, New Jersey, 1999.

Stephanopoulos G., Chemical Process Control: An Introduction to Theory and Practice, Englewood Cliffs, New Jersey, 1984.



Podati koncept dinamičnega modeliranja in regulacije (bio)kemijskih procesnih enot in obratov in spoznati diskretno-kontinuirno optimiranje oz. sintezo procesov.

The main is to give concept of dynamic modeling and control of process units and (bio)chemical plants, and to present knowledge of discrete-continuous process optimization and synthesis.

Predvideni študijski rezultati: Intended learning outcomes:

Znanje in razumevanje:

obvladovanje modeliranja, dinamike, regulacije in vodenja (bio)kemijskih procesov,

obvladovanje teorije in aplikacij matematičnega programiranja pri načrtovanju, planiranju in obratovanju (bio)kemijskih procesov.

Prenesljive/ključne spretnosti in drugi atributi: Imeti razumevanje o vplivu regulacijskih in optimizacijskih rešitev na varno, okolju prijazno in

Knowledge and Understanding:

to have knowledge of modeling, dynamics and control of (bio)chemical processes,

to understand theory and have knowledge of some practical applications of mathematical programming in designing, planning and operating (bio)chemical processes.

Transferable/Key Skills and other attributes: To have an understanding of the impact of control and optimization solutions on safe, environmentally

12

ekonomsko učinkovito delovanje kemijskih in biokemijskih procesov.

benign and economically effective operation of chemical and biochemical processes.


Predavanja, seminar, laboratorijske in računalniške vaje, samostojno delo študenta.

Lectures, seminar work, laboratory and computer practice, self-learning.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: teoretični del izpita računski del izpita Računski del izpita je mogoče nadomestiti z dvema računskima testoma. Teoretični del izpita je mogoče nadomestiti z dvema testoma teorije. Teoretični in računski del izpita/testa se izvajata sočasno.

30 70

Student has to pass successfully the following obligations: Theoretical part of exam Calculus part of exam Calculus part of the exam can be replaced by two calculus tests. Theoretical part of the exam can be replaced by two theoretical tests. Theory and calculus parts of the exam or test are performed simultaneously.


AHMETOVIĆ, Elvis, KRAVANJA, Zdravko. Simultaneous optimization of heat-integrated water networks involving process-to-process streams for heat integration. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2014, vol. 62, iss. 1, str. 302-217, doi: 10.1016/j.applthermaleng.2013.06.010.

NEMET, Andreja, KLEMEŠ, Jiri, KRAVANJA, Zdravko. Designing a Total Site for an entire lifetime under fluctuating utility prices. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], Available online 18 July 2014, vol. , str. 1-24, doi: 10.1016/j.compchemeng.2014.07.004.

ČUČEK, Lidija, MARTÍN, Mariano, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Multi-period synthesis of optimally-integrated biomass and bioenergy supply network. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], 4 Jul. 2014, vol. 66, str. 57-70, doi: 10.1016/j.compchemeng.2014.02.020.

KRAVANJA, Zdravko, ČUČEK, Lidija. Multi-objective optimisation for generating sustainable solutions considering total effects on the environment. V: DUIĆ, Neven (ur.). Sustainable development of energy, water and environment systems, (Applied Energy, ISSN 0306-2619, Vol. 101, (2012)). Oxford: Elsevier, cop. 2012, vol. 101, str. 67-80, doi: 10.1016/j.apenergy.2012.04.025.

ČUČEK, Lidija, KLEMEŠ, Jiri, KRAVANJA, Zdravko. A Review of Footprint analysis tools for monitoring impacts on sustainability. Journal of cleaner production, ISSN 0959-6526. [Print ed.], Oct. 2012, vol. 34, str. 9-20, doi: 10.1016/j.jclepro.2012.02.036.

13

Razvoj produktov in procesov


Predmet: Razvoj produktov in procesov

Course title: Product and Process Development




Semester Semester


1. letni

Spring



Predavanja


Sem. vaje Tutorial




ECTS

30 15 135 6


Jeziki: Languages:




Prerequisites:

Pogojev ni. None.

Vsebina:


- Uporaba matematike v tehniški ekonomiki. - Stopnje v sistematičnem razvoju produktov in

procesov. - Dimenzioniranje in investicijsko vrednotenje

procesne opreme. Vpliv inflacije na ceno. - Ocenjevanje investicije osnovnih sredstev. - Amortizacija. - Prihodki in obratovalni stroški. - Ocenjevanje investicije obratnih sredstev. - Statični in dinamični kriteriji ekonomske

upravičenosti. - Analiza denarnih tokov. - Izbor med alternativami. - Inkrementalna ekonomska analiza. - Negotovost in tveganje pri ekonomski analizi. Vaje: - Priprava projektne dokumentacije. - Ocenjevanje investicije z računalniškimi

programi in literaturnimi viri.

- Mathematics in engineering economics. - Steps in systematic product and process

development. - Equipment sizing and costing. Effect of inflation. - Fixed capital cost estimation. - Depreciation. - Annual sales revenues and production costs. - Working capital and total capital investment. - Static and dynamic profitability measures. - Cash flow analysis. - Selection between alternatives. - Incremental analysis. - Uncertainty and risk in economic evaluation. Labor work: - Preparation of project documentation. - Evaluation of capital cost by applying advanced

software tools and literature. - Feasibility study of the selected production plant

including detailed economic analysis.

14

- Izdelava študije možnosti za izbrani proces s podrobno ekonomsko analizo.

- Analize občutljivosti.

- Sensitivity analyses.


Z. Novak Pintarič: Razvoj procesov v kemijski industriji, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014. http://www.fkkt.um.si/egradiva/fajli/Razvoj_procesov.pdf

Z. Novak Pintarič: Razvoj produktov in procesov: zbirka nalog za računske vaje. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. https://estudij.um.si/mod/resource/view.php?id=38331, http://dkum.uni-mb.si/IzpisGradiva.php?id=44464. [COBISS.SI-ID 17584150]


R. A. Brealey, S. C. Myers, A. J. Marcus: Fundamentals of Corporate Finance. Sixth Edition, McGraw Hill, New York, 2009.

W. D. Seider, J. D. Seader, D. R. Lewin: Product and process design principles: synthesis, analysis, and evaluation. Second Edition, Wiley, New York, 2004.

A. Chauvel, G. Fournier, C. Raimbault: Manual of Process Economic Evaluation. Editions Technip, Paris, 2003.



Cilji tega predmeta so: - integracija znanj, ki jih dobijo študentje

predhodno pri specifičnih tehniških predmetih, - obvladovanje stopenj v razvoju kemijskih in

biokemijskih produktov in procesov, - osvojitev metodologije za pripravo študije

možnosti in ocenjevanje ekonomske upravičenosti.

The objectives of this course are: - integration of students' knowledge and skills

acquainted by specific engineering subjects, - to acquire the steps in integral approach for

development of chemical and biochemical products and processes,

- to acquire the methodology for performing feasibility studies with economic evaluation.



Študent bo sposoben: - Oceniti vrednost investicije, prihodkov,

obratovalnih stroškov, amortizacije in drugih odhodkov procesa.

- Izračunati ekonomske kriterije za projekt (donosnost investicije, doba vračanja, neto sedanja vrednost, interna stopnja donosnosti itd.).

- Izvesti študije možnosti z uporabo metod tehniške ekonomike.

- Primerjati več alternativnih projektov z metodami inkrementalne analize in izbrati ekonomsko najugodnejšega.

- Izpeljati tehnološki projekt od ideje do realizacije.

Student will be able to: - Assess the values of investment, revenue,

operating cost, annual depreciation and other expenses of a process.

- Calculate the economic indicators of a project (return on investment, payback time, net present value, internal rate of return etc.).

- Prepare feasibility studies by using engineering economics methods.

- Compare several alternative projects by using incremental analysis, and choose economically the best option.

- Manage technical project from idea to realization.

Prenesljive/ključne spretnosti in drugi atributi: - kreiranje idej in inovativnih tehnoloških rešitev, - uporabo strokovnih in znanstvenih informacijskih

virov, - določevanje prioritet pri izvajanju projektov, - časovno planiranje in vodenje tehnoloških

Transferable/Key Skills and other attributes: The student is able to: - create ideas and solve problems inventively, - use technical and scientific information sources, - determine priorities by executing the projects, - plan and manage technological projects,

15

projektov, sprejemanje odločitev, - timsko delo pri razvoju tehnoloških projektov od

ideje do realizacije, - izdelavo projektnih poročil in ustno

komuniciranje o problematiki v globalnem tržnem okolju.

- team work for project development from idea to realization,

- write reports, - present material orally.


- predavanja, - računski in študijski primeri, domače naloge, - uporaba računalniških programov za ekonomske

analize, - aktivno skupinsko delo za izdelavo projektne

naloge s študijo možnosti.

- lectures, - calculating examples, case studies, homeworks, - use of computer tools in economic analyses - active team work for preparation of project with

feasibility study.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - pisni računski test ali izpit - izpit teorije - projektno poročilo Izpit teorije se lahko izvaja ustno ali pisno.

60 20 20

Student has to pass successfully the following obligations: - written test or examination (calculus) - theory examination - written report on project work Theory examination can be performed orally or in writing.


NOVAK-PINTARIČ, Zorka, IBRIĆ, Nidret, AHMETOVIĆ, Elvis, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Designing optimal water networks for the appropriate economic criteria. V: 21st International Congress of Chemical and Process Engineering CHISA 2014 [and] 17th Conference PRES 2014, 23 - 27 August 2014, Praha, Czech Republic. Praha: [s. n.], 2014, 1 str. [COBISS.SI-ID 18099478]

KASAŠ, Mihael, KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka. Achieving profitably, operationally, and environmentally compromise flow-sheet designs by a single-criterion optimization. AIChE journal, ISSN 0001-1541. [Print ed.], July 2012, vol. 58, iss. 7, str. 2131-2141, doi: 10.1002/aic.12747. [COBISS.SI-ID 15215126]

KASAŠ, Mihael, KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka. Suitable modeling for process flow sheet optimization using the correct economic criterion. Industrial & engineering chemistry research, ISSN 0888-5885. [Print ed.], 2011, vol. 50, iss. 6, str. 3356-3370, doi: 10.1021/ie101485z. [COBISS.SI-ID 14805526]

NOVAK-PINTARIČ, Zorka. Navodila za uporabo programa Aspen Process Economic Analyzer : za vaje pri predmetu Razvoj produktov in procesov. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [8] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=38332,http://dkum.uni-mb.si/IzpisGradiva.php?id=44462. [COBISS.SI-ID 17584406]

NOVAK-PINTARIČ, Zorka. Razvoj produktov in procesov: zbirka nalog za računske vaje. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [14] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=38331, http://dkum.uni-mb.si/IzpisGradiva.php?id=44464. [COBISS.SI-ID 17584150]

http://cobiss.izum.si/scripts/cobiss?command=DISPLAY&base=COBIB&RID=18099478

16

Procesne naprave


Predmet: Procesne naprave

Course title: Process Equipment


Študijska smer

Study field

Letnik

Academic year

Semester

Semester


1. letni

Spring



Predavanja

Lectures

Seminar

Seminar

Sem. vaje

Tutorial

Lab. vaje

Laboratory

work

Teren. vaje

Field work

Samost. delo

Individ. work ECTS

30

30 120 6

Nosilec predmeta / Lecturer: Darko Goričanec

Jeziki /

Languages:



Pogoji za vključitev v delo oz. za opravljanje

študijskih obveznosti:

Prerequisits:

Osnovno znanje mehanike fluidov in prenosa

toplote.

Basic knowledge of fluid mechanics and heat

transfer.


Posode: dimenzioniranje, prenos toplote v mešalnih posodah, padec tlaka fluida za gretje ali hlajenje.

Ločevalniki in zbirne posode: dimenzioniranje ločevalnikov in zbirnih posod.

Naprave za prenos kapljevin: cevovodi, regulacijski ventili, zaporni elementi, merjenje pretoka.

Črpalke: izbira črpalke, potrebna moč, dvig temperature kapljevine.

Naprave za prenos plinov: cevovodi, batni, vijačni in turbo kompresorji, pnevmatski transport, potrebna moč ventilatorja, padec tlaka.

Vessels: designing, heat transfer within the agitated vessels, pressure drop of the heating or cooling fluid,

Separators and accumulation tanks: dimensioning of separators and accumulation tanks,

Equipment for fluid transfer: piping, valves, flow measurements.

Pumps: pump selection, power calculation, temperature raise of the liquid.

Equipment for the transfer of gases: piping, reciprocating, piston, screw and turbo compressors, pneumatic transport, the necessary power of a ventilator, pressure drop.

Heat exchangers: dimensioning, heat transfer,

17

Prenosniki toplote: dimenzioniranje, prenos toplote, padec tlaka.

Kotli in kondenzatorji: dimenzioniranje, prenos toplote, padec tlaka.

Vakuumski sistemi: ejektorji, nepropustnost vakuumskega sistema.

Hladilna tehnika: procesi hlajenja, kompresijske in absorbcijske toplotne črpalke.

Prezračevanje: tehnološki postopki obdelave zraka, prezračevanje laboratorijev in industrijskih objektov.

Statična mešala: osnovne značilnosti in dimenzioniranje statičnih mešal.

Projektno delo temelji na primerih, ki se navezujejo na predmet in krajši projektni nalogi.

pressure drop.

Boilers and condensers: dimensioning, heat transfer, pressure drop.

Vacuum systems: ejectors, tightness of a vacuum system.

Cooling techniques: cooling processes, compression and absorption heat pumps.

Ventilation: air treatment techniques, ventilation of laboratories and industrial buildings.

Static mixers: basic properties and dimensioning of static mixers.

Project work is based on a chosen topic of the subject and short process design project.


Goričanec, Darko, Trop Peter Procesne naprave: zbrano gradivo pri predmetu Procesne naprave (dopolnjena izdaja). Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, 2016.


Charles E. Thomas: Process Technology Equipment and Systems, Cengage Learning; 4 edition, 2014.

CAPT: Process Technology Equipment, Prentice Hall; 1 edition, 2009.



Razviti sposobnost študentov za samostojno in kreativno reševanje inženirskih problemov.

Razumevanje delovanja procesnih sistemov.

Načrtovanje učinkovitejših procesnih sistemov.

To further develop student's capabilities of independent thinking and creative solution of engineering problems.

Understanding the functioning of process systems.

Designing more efficient process systems.



Razumevanje povezave različnih znanj in postopkov ter pomena uporabe strokovne literature za učinkovito reševanje inženirskih problemov.


Understanding of relationships between different skills and procedures and importance of professional literature for efficient solutions of process problems.

Prenesljive/ključne spretnosti in drugi atributi:

Kombinirana uporaba različnih naprednih znanj za reševanje inženirskih problemov

Z mentorskim reševanjem konkretnih primerov se oblikuje študentova kreativnost in logično razmišljanje, potrebno za uspešno delo v praksi.

Transferable/Key Skills and other attributes:

Combined use of different fundamental skills for solution of engineering problems.

Solving concrete examples under supervision and hence developing student’s creativity and logical thinking, needed for successful work in practice.



18

Predavanja: študent spozna teoretične vsebine predmeta. Laboratorijske vaje: študent utrdi teoretično znanje in spozna aplikativne možnosti reševanja primerov iz prakse, študent izdela krajšo študijo oz. projekt, ki se navezuje na tematiko predmeta.

Lectures: the student gets acquainted with theoretical content of the subject. Laboratory work: the student upgrades the theoretical knowledge with practical experience, conducting a short study or project regarding the thematic of the subject.


Delež (v %) /

Weight (in %)

Assessment:

Izpit je opravljen, če so pozitivno opravljene

vse naslednje obveznosti:

seminarska naloga

teoretični del izpita

računski del izpita Teoretični in računski del tvorita celoto in se preverjata hkrati.

20 30 50

Student has to pass successfully the

following obligations:

seminar

theoretical part of the exam

calculation part of the exam The theoretical and the calculus part of the exam are performed simultaneously.


GORIČANEC, Darko, POZEB, Viljem, TOMŠIČ, Ladislav, TROP, Peter. Exploitation of the waste-heat from hydro power plants. Energy, ISSN 0360-5442. [Print ed.], Available online 22 July 2014, str. 1-6.

ANICIC, B., TROP, Peter, GORIČANEC, Darko. Comparison between two methods of methanol production from carbon dioxide. Energy, ISSN 0360-5442. [Print ed.], 2014, 77, str. 279-289, doi: 10.1016/j.energy.2014.09.069. [COBISS.SI-ID 80681729].

DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Dryers for sewage sludge dehydration. International journal of energy and environment, 2012, vol. 6, iss. 6, str. 588-596. http://www.naun.org/multimedia/NAUN/energyenvironment/16-691.pdf. [COBISS.SI-ID 16535062].

KULČAR, Bojan, GORIČANEC, Darko, KROPE, Jurij. Economy of replacing a refrigerant in a cooling system for preparing chilled water = Remplacement du frigorigene dans un systeme utilisé pour préparer de l'eau glacée : impact financier. International journal of refrigeration, ISSN 0140-7007. [Print ed.], Aug. 2010, vol. 33, iss. 5, str. 989-994.

ŽLAK, Janez, AGREŽ, Marko, DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Rentability of rotary heat regenerator use in ventilating systems = Rentabilnost upotrebe regeneratora topline u ventilacijskom sustavu. Strojarstvo, ISSN 0562-1887, 2010, vol. 52, no. 6, str. 665-671. [COBISS.SI-ID 15454486].

Bioseparacijska tehnika in biokataliza


19


Predmet: Bioseparacijska tehnika in biokataliza

Course title: Bioseparation Processes and Biocatalysis




Semester Semester


1. letni

Spring



Predavanja


Sem. vaje Tutorial




ECTS

45 30 105 6

Nosilec predmeta / Lecturer: Željko Knez, Maja Leitgeb

Jeziki / Languages:




Prerequisites:

Potrebno je znanje separacijske tehnike ter osnovno znanje biokemije, biokemijske tehnike in biotehnologije.

Knowledge of separation processes and basic knowledge of biochemistry, biochemical engineering and biotechnooogy is needed.

Vsebina:


- Bioseparacijska tehnika: Separacija (flokulacija in flotacija, filtracija, centrifugiranje), koncentriranje (ekstrakcija, membranski procesi), sušenje.

- Biokataliza: kinetika biokataliziranih reakcij, določevanje kinetičnih parametrov, imobilizacija biokatalizatrojev, modeliranje biokataliziranih reakcij. Projektno delo bo potekalo na osnovi laboratorijskih eksperimentov s področja biokatalitičnih procesov, kjer bodo istočasno zajeti tudi bioseparacijski procesi.

- Bioseparation processes: Separation (flocculation and flotation, filtration, centrifugation), concentration (extraction, membrane processes), drying.

- Biocatalysis: kinetic of biocatalyzed reactions, determination of kinetic parameters,immobilization of biocatalysts, modelling of biocatalyzed reactions. Project will be based on experimental work from the field of biocatalytic processes, integrated with bioseparation processes.

20


B. Elvers, S. Hawkins, W. E Russey: Ullmann's encyclopedia of industrial chemistry, izbrana poglavja, Weinheim, Cambridge: Wiley-VCH, 2003.


M. C. Flickinger, Upstream and Downstream Industrial Biotechnology, 3V Bundle, Wiley, ISBN: 978-1-118-13125-1, 2014.

M. C. Flickinger, Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology , 7 Volume Set, Wiley, ISBN: 978-0-471-79930-6, 2010.

A. Illanes, L. Wilson, C. Vera, Problem Solving in Enzyme Biocatalysis, Wiley, ISBN: 978-1-118-34171-1, 2013.

J. A. Tao, R. J. Kazlauskas, Biocatalysis for Green Chemistry and Chemical Process Development, Wiley, ISBN: 978-0-470-43778-0, 2011.



Na osnovi projektnega dela spoznati bioseparacijske metode ter poglobljena znanja iz biokatalize.

On the basis of project work the sudets will get the knowledge about bioseparation processes, as well as advanced knowledge of biocatalysis.



Znanje in razumevanje: Zmožnost načrtovanja biokatalitskega sistema; uporaba ustreznih bioseparacijskih metod v povezavi z biokataliziranim sistemom.

Knowledge and Understanding: Design of biocatalytic systems; application of bioseparation processes for a defined biocatalytic system.

Prenesljive/ključne spretnosti in drugi atributi: Vsebina predmeta je povezana z ostalimi predmeti na smeri Biokemijska tehnika in podaja znanja, ki so nujno potrebna za razumevanje vsebin, ki so zajete pri predmetih Industrijska mikrobiologija in Bioreakcijska tehnika.

Transferable/Key Skills and other attributes: The subject is strongly connected to the other subjects on the direction Biochemical engineering and gives the knowledge which is necessarry for understanding other subjects, such as Industrial microbiology and Bioreaction engineering.



Predavanja v učilnici, ki je opremljena z avdio-vizualnimi pripomočki. Individualna priprava projektne naloge s predstavitvijo in diskusijo.

Lectures in lecture room, equipped with audio-visual equipment Individual preparation of project work with the presentation with discussion.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - ustni izpit - projektno poročilo - predstavitev projekta

50 25 25

Student has to pass successfully the following obligations: - oral examination - project written report - project oral presentation

21


KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja, LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102]

ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46 (3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598]

CSANÁDI, Zsófia, BÉLAFI-BAKÓ, Katalin, SZENTGYÖRGYI, Eszter, GUBICZA, László, KNEZ, Željko, LEITGEB, Maja. Enzymatic esterification of glycerol and stearic acid in non-conventional media. Acta chimica slovenica, ISSN 1318-0207. 2010, 57 (1), 244-249. COBISS.SI-ID 14029590]

ŠULEK, Franja, KNEZ, Željko, LEITGEB, Maja. Immobilization of cholesterol oxidase to finely dispersed silica-coated maghemite nanoparticles based magnetic fluid. Applied Surface Science, ISSN 0169-4332. 2010, 256 (14), 4596-4600. [COBISS.SI-ID 14055446]

THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology, ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222]

22

Bioreakcijska tehnika


Predmet: Bioreakcijska tehnika

Course title: Bioreaction Engineering




Semester Semester


1. letni

Summer



Predavanja


Sem. vaje Tutorial



amost. delo Individ. work

ECTS

30 30 120 6

Nosilec predmeta / Lecturer: Andreja Goršek

Jeziki / Languages: Predavanja / Lecture: slovenski / Slovene



Prerequisites:

Potrebna so osnovna znanja termodinamike, biokemije, biokemijske in reakcijske tehnike.

Basic knowledge about thermodynamics, biochemistry and reaction engineering is required.


Predavanja: Uvodni pojmi. Bioreakcijska kinetika (encimska in mikrobiološka). Tipi bioreaktorjev: osnovni (mešalni, kolonski, z dvigovanjem zraka) in posebni tipi. Tehnološke zahteve pri načrtovanju bioreaktorjev (mešanje, snovni in toplotni prenos). Modeliranje biokemijskih reakcijskih sistemov (šaržni, pretočni, kaskada pretočnih bioreaktorjev, šaržni z dotokom substrata). Ekonomika bioprocesov. Laboratorijske vaje: Poudarek je na načrtovanju bioreaktorjev:

aerobni reaktor

anaerobni reaktor

aeracijska enota

Lectures: Fundamentals. Bioreaction kinetics (enzymatic and microbial) Type of bioreactors: basic (mixed, bubble column, airlift) and special types. Technological requirements in bioreactor design (mixing, mass transfer, heat transfer). Modeling of biochemical reaction systems (batch, continuous, continuous in series, fed-batch). Bioprocess economics Laboratorial exercises: The main emphasis is focused on bioreactor design:

aerobic reactor

anaerobic reactor

aeration unit

23

Projektno delo: Študentje izberejo bioproces, ga analizirajo in pripravijo predstavitev.

Project work: Student choose a bioprocess, perform the analysis and prepare public presentation.


A. Goršek. Bioreakcijska tehnika: zbrano gradivo, http://www.fkkt.um.si/egradiva/fajli/brt.pdf, 2007.

M. Tramšek, A. Goršek, Bioreakcijska tehnika: navodila za laboratorijske vaje, UM FKKT, 2005.

Levenspiel, Chemical Reaction Engineering, John Wiley & Sons, New York, 1999.


P. M. Doran, Bioprocess Engineering Principles, Elsevier Ltd., London, 2004.

I. J. Dunnn, E. Heinzle, J. Ingham, J.E. Prenosil, Biological reaction Engineering, Dinamic Modelling Fundamentals with Simulation Examples, Wiley-VCH, Weinheim, 2003.



Vključevanje principov kemijske reakcijske tehnike v biokemijske sisteme. Predstavitev različnih tipov, konfiguracij in aplikacij bioreaktorjev ter fermentorjev. Seznanitev z osnovnimi in kompleksnejšimi biokinetičnimi modeli ter njihovo uporabo pri modeliranju šaržnih, semi-kontinuiranih in kontinuiranih bioreaktorskih sistemov.

Incorporating the principles of chemical reaction engineering in biochemical systems. Presenting the different types, configurations and applications of bioreactors and fermentors. Introducing the basic and complex biokinetic models and their application in modeling of batch, semi-continuous and continuous bioreactor systems.


Znanje in razumevanje: Razumevanje principov encimskih in mikrobnih reakcij. Poznavanje stehiometrije, in kinetike biokemijskih reakcij. Poznavanje snovnih bilanc bioprocesov v dinamičnem ter stacinarnem stanju. Dinamično modeliranje različnih tipov bioreaktorjev.

Knowledge and Understanding: Understanding the principles of enzymatic and microbial reactions. Knowledge the stehiometry and kinetics of biochemical reactions. Knowledge of the unsteady and steady-state material balances of bioprocesses. Dynamic modeling of different bioreactor types.

Prenesljive/ključne spretnosti in drugi atributi: Modeliranje mikrobiološke rasti in encimskih reakcij z ali brez inhibicije. Izvajanje osnovnih tehnoloških izračunov za načrtovanje bioreaktorjev, upoštevajoč velikost, mešalni režim in kapaciteto snovnega prenosa.

Transferable/Key Skills and other attributes: Modeling of microbial growth and enzymatic reactions with or without inhibition. Executing of basic reaction engineering calculations for bioreactors design including size, stirrer regime and mass transfer capacity.



Predavanja, obogatena z računskimi primeri, multimedijskim materialom (simulacije, slike, diagrami) in primeri iz industrije.

Pomoč pri reševanju računskih nalog.

Individualno delo – priprava projekta in javna predstavitev.

Pomoč pri iskanju biokemijskih informacij in podatkov na spletu ter drugih elektronskih virih.

Pisno reševanje nalog.

Lectures, enriched with numerical problems, multimedia material (simulations, pictures, diagrams) and case studies from industry

Helping students at solving numerical problems.

Individual work – project preparation and public presentation.

Helping students with biochemical data searching on internet and other electronic sources.

Written test on problem solving skills.

24



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti:

pisno poročilo o laboratorijskih vajah

projektno poročilo

pisni izpit

30 20 50


laboratory work written report

project report

written exam


ZAJŠEK, Katja, KOLAR, Mitja, GORŠEK, Andreja. Characterisation of the exopolysaccharide kefiran produced by lactic acid bacteria entrapped within natural kefir grains. International journal of dairy technology, ISSN 1364-727X, 2011, vol. 64, issue 4, str. 544-548, doi: 10.1111/j.1471-0307.2011.00704.x. [COBISS.SI-ID 15278870].

ZAJŠEK, Katja, GORŠEK, Andreja. Experimental assessment of the impact of cultivation conditions on kefiran production by the mixed microflora imbedded in kefir grains. V: 9th International Conference on Chemical and Process Engineering, 8-11 May, 2011, Florence, Italy. PIERUCCI, Sauro (ur.). ICheaP-10, (Chemical Engineering transactions, ISSN 1974-9791, Vol. 24). Milano: AIDIC, 2011, str. 481-486, doi: 10.3303/CET1124081. [COBISS.SI-ID 14955798].

PEČAR, Darja, SLEMNIK, Mojca, GORŠEK, Andreja. Testing the corrosion resistance of stainless steels during the fermentation of probiotic drink. Journal of the Science of Food and Agriculture, ISSN 0022-5142, May 2011, vol. 91, iss. 7, str. 1293-1297, doi: 10.1002/jsfa.4315. [COBISS.SI-ID 14809622].

ZAJŠEK, Katja, GORŠEK, Andreja, KOLAR, Mitja. Cultivating conditions effects on kefiran production by the mixed culture of lactic acid bacteria imbedded within kefir grains. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2013, vol. 139, iss. 1-4, str. 970-977, doi: 10.1016/j.foodchem.2012.11.142. [COBISS.SI-ID 16645142].

VNUČEC, Doroteja, GORŠEK, Andreja, KUTNAR, Andreja, MIKULJAN, Marica. A new method of physical modification of soy proteins for wood adhesives. V: International conference on wood adhesives : 9-11 october, 2013, Toronto, Ontario, Canada. [Madison]: Forest Products Society, 2014, str. 570-576, ilustr. [COBISS.SI-ID 1536529092].

http://dx.doi.org/10.1111/j.1471-0307.2011.00704.x


http://dx.doi.org/10.3303/CET1124081


http://dx.doi.org/10.1002/jsfa.4315


http://dx.doi.org/10.1016/j.foodchem.2012.11.142



25

Načrtovanje procesov - projekt


Predmet: Načrtovanje procesov - projekt

Course title: Process Design - Project Načrtovanje procesov - projekt




Semester Semester


Kemijska tehnika Chemical Engineering

1. letni

Spring



Predavanja


Sem. vaje Tutorial




ECTS

45 135 6


Jeziki / Languages:

Predavanja / Lecture:



Prerequisites:

Potrebno je znanje iz termodinamike, prenosa toplote in snovi ter osnovno znanje iz separacijske in reakcijske tehnike.

Knowledge of thermodynamics, heat and mass transfer and basic knowledge of separation and reaction engineering is required.

Vsebina:


Računalniške vaje - projekt: Izbor procesa, sinteza procesne sheme. Simulacija procesa z rigoroznimi modeli in termodinamiko. Termodinamska analiza, toplotna integracija, načrtovanje omrežja toplotnih prenosnikov. Ekonomsko in okoljsko vrednotenje procesa. Priprava razširjenega projektnega poročila. Ustna predstavitev projekta.

Computer Exercises - project: Selection of process, synthesis of process flow sheet. Process simulation using rigorous models and thermodynamics. Thermodynamic analysis, heat integration, Heat Exchanger Network design. Process economics and environmental evaluation. Preparation of extended written project report. Oral presentation of project.


Z. Novak Pintarič, Načrtovanje in integracija procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014.

Z. Novak Pintarič, Simulacija kemijskih procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014.

M. Bogataj, A. Goršek, P. Glavič, Načrtovanje procesov, Navodila za vaje, Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2005.


26


J. J. Klemeš (Ed.), Handbook of Process Integration (PI), Woodhead Publishing, Cambridge, 2013.


Sinteza znanj iz kemije, termodinamike, osnovnih pojavov in operacij, varnosti in okolja, ekonomike

Synthesis of knowledge, acquired in: chemistry, basic phenomena, thermodynamics, unit operations, safety, environmental protection, economics, etc.



Študent bo sposoben: - Izvesti simulacijo in toplotno integracijo procesa

z uporabo računalniških programov. - Povezati znanja, pridobljena pri predhodnih

predmetih, in jih uporabiti pri načrtovanju kemijskih in drugih procesov.

- Izvesti konceptualno načrtovanje kontinuirnih in šaržnih procesov z uporabo metod kemijske procesne tehnike.

- Predlagati tehnološke in obratovalne izboljšave procesnih shem.

- Primerjati alternativne procesne načrte glede na tehnološko učinkovitost in enostavno ekonomsko oceno.

Student will be able to: - Make process simulation and heat integration by

using computer programs. - Combine knowledge gained through previous

courses and use it for designing chemical and other processes.

- Manage the conceptual design of continuous and batch processes by using chemical process engineering methods.

- Propose technical and operational improvements of process flow sheets.

- Compare alternative process designs according to technical efficiency and simplified economic assessment.

Prenesljive/ključne spretnosti in drugi atributi: Računalniško načrtovanje zahtevnejših celotnih procesnih shem. Razvijanje sposobnosti za skupinsko in projektno delo. Pisno in ustno izražanje.

Transferable/key skills and other attributes: Computer aided design and retrofit of more complex total process systems. Abilities to work in team. Experience in executing large projects. Written and oral communication.



Uporaba tujih jezikov in literature. Skupinske računalniške vaje simuliranja, integriranja, načrtovanja, optimiranja procesa, ekonomskega vrednotenja investicij. Pisanje in zagovor skupinskega projektnega poročila.

Usage of foreign languages and literature. Team-work in process simulation, integration, design, optimization, and economic evaluation of the investment. Writing and defence of the team design report.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - projektno delo - projektno poročilo - predstavitev projekta

10 60 30

Student has to pass successfully the following obligations: - project work - project report - project presentation


NOVAK-PINTARIČ, Zorka, KRAVANJA, Zdravko. Suitable process modelling for proper multi-objective optimization of process flow sheets. V: KLEMEŠ, Jiri (ur.), VARBANOV, Petar (ur.), LIEW, Peng Yen (ur.). 24th European Symposium on Computer Aided Process Engineering : [ESCAPE-24, 15 to 18 June 2014, Budapest, Hungary], (Computer aided chemical engineering, ISSN 1570-7946, 33). Amsterdam ... [et al.]: Elsevier, cop. 2014, str. 1388-

27

1392. [COBISS.SI-ID 18172438]

KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka, SIMONIČ, Marjana, ŠKOF, Gorazd. Optimizacija obstoječe in načrtovanje nove naprave za čiščenja odpadnih oljnih emulzij : zaključno poročilo projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, Laboratorij za procesno sistemsko tehniko in trajnostni razvoj, 2013. 53 str., ilustr. [COBISS.SI-ID 17120534]

TOKOS, Hella, NOVAK-PINTARIČ, Zorka, GLAVIČ, Peter. Energy saving opportunities in heat integrated beverage plant retrofit. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2010, vol. 30, no. 1, str. 36-44, doi: 10.1016/j.applthermaleng.2009.03.008. [COBISS.SI-ID 13122838]

NOVAK-PINTARIČ, Zorka. Načrtovanje in integracija procesov : zbrano gradivo za predmet Načrtovanje procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [145] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21344, http://dkum.uni-mb.si/IzpisGradiva.php?id=44461. [COBISS.SI-ID 17583638]

NOVAK-PINTARIČ, Zorka. Simulacija kemijskih procesov : zbrano gradivo za vaje pri predmetu Načrtovanje procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [37] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21375, http://dkum.uni-mb.si/IzpisGradiva.php?id=44466. [COBISS.SI-ID 17583894]

28

Industrijska mikrobiologija


Predmet: Industrijska mikrobiologija

Course title: Industrial Microbiology




Semester Semester


Biokemijska tehnika Biochemical Engineering

1. letni

Summer

Vrsta predmeta / Course type Obvezni / Obligatory


Predavanja


Sem. vaje Tutorial




ECTS

30 15 135 6

Nosilec predmeta / Lecturer: Maja Leitgeb

Jeziki / Languages:




Prerequisites:

Potrebno je znanje iz separacijske tehnike ter osnovno znanje mikrobiologije, biokemije, biokemijske tehnike in biotehnologije.

Knowledge of separation processes and basic knowledge of microbiology, biochemistry, biochemical engineering and biotechnology is needed.


Definicija industrijske mikrobiologije. Oprema za fermentacijo in njena uporaba. Rast in nastajanje produktov; gojenje celic, celična kinetika. Kinetka biokataliziranih reakcij z dvema ali več substrati. Detekcija in analiza fermentacijskih produktov (fizikalno-kemijske in biološke analize). Fermentacijski mediji: sestava, sterilizacija, kontaminacija, cepitev, analiza. Sterilizacija (šaržna, kontinuirana, sterilizacija zraka). Downstream processing (separacija, razbitje celic, izolacija produktov in njihovo čiščenje). Industrijski mikroorganizmi. Industrijski procesi in produkti: Mikrobni encimi.

Definition of industrial microbiology. Fermentation equipment and its use. Industrial microorganisms and products. Inoculum preparation. Kinetic of biocatalyzed reactions with two or more substrates. Detection and assay of fermentation products (physical – chemical assays and biological assays). Fermentation media (composition, sterilization and contamination, inoculum media). Sterilization (batch, continuous, sterilization of air). Industrial microorganisms. Downstream processing (separation, product isolation, ...). Industrial microorganisms. Industrial processes and products: Microbial enzymes.

29

Antibiotiki: penicilin, streptomicin, drugi antibiotiki. Anaerobne fermentacije. Glicerol. Vitamini. Indirektna in direktna fermentacija. Mikrobna oksidativna transformacija substrata: vinski kis, glukonska kislina. Mikrobne celice kot fermentacijski produkti (pekovski kvas, kvas za prehrano in krmo, bakterijski insekticidi, glive, alge). Organske kisline: citronska kislina, fumarna kislina. Genska kontrola metabolnih poti. Laboratorijske vaje s področja sterilizacije in fermentacijskih procesov.

Antibiotic fermentations (penicillin, streptomycin, and others). Anaerobic fermentations. Glycerol. Vitamins. Indirect and direct fermentation. Microbial oxidative transformations of substrate: vinegar, gluconic acid. Microbial cells as fermentation products (bakers’ yeast, food and feed yeasts, bacterial insecticides, mushrooms, algae). Organic acids (citric acid, fumaric acid). Genetic control of metabolic pathways. Laboratory work in the field of sterilization and fermentation processes.


M. J. Waites, N. L. Morgan, J. S. Rockey, G. Highton, Industrial Microbiology, Blackwell Publishing, London, 2004.


L. E. Casida, Industrial microbiology, John Wiley and Sons, New York, 2003. M. T. Madigar, J. M. Martinko, D. Stahl, D. P. Clark, Brock Biology of Microorganisms, 13th ed., Prentice

Hall, London, 2010.

Murray R. K., Granner D. K., Mayes P. A., Rodwell V. W. Harper’s Biochemistry, 24th ed. Prentice Hall, London, 2010.

G. Lear, G. D. Lewis, Microbial Biofilms: Current Research and Applications, Caister Academic Press, New Zealand, 2012.



Pregled znanj s področja industrijske mikrobiologije; od izolacije kultur, njihove ohranitve, proizvodnje določenih produktov, do načrtovanja fermentacijskih procesov.

Overview of knowledge in the field of industrial microbiology; from isolation of cultures, their preservation, production of desired products, to design of fermentation processes.


Znanje in razumevanje: Uporaba mikroorganizmov z njihovimi zelo različnimi metabolnimi aktivnostmi za industrijske aplikacije – procese in produkte z visoko ekonomskim, okoljskim in socialnim pomenom.

Knowledge and Understanding: The use of microorganisms, with their extremely diverse metabolic activities, for industrial applications – processes and products that are of major economic, environmental and social importance.

Prenesljive/ključne spretnosti in drugi atributi: Predmet se dopoljnjuje z ostalimi vsebinami smeri Biokemijska tehnika.

Transferable/Key Skills and other attributes: The subject is related to the other subjects on the study field Biochemical engineering.


Predavanja v učilnici, ki je opremljena z avdio-vizualnimi pripomočki. Individualna priprava seminarskih nalog s predstavitvijo in diskusijo. Laboratorijsko delo na izbranem primeru.

Lectures in lecture room, equipped with audio-visual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on selected case.

30



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje (dnevnik, kolokvij) - pisni izpit - ustni izpit

20 40 40

Student has to pass successfully the following obligations: - completed lab work (report, colloquium) - written examination - oral examination


LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SI-ID 16864790]

ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 0896-8446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462]



KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN 0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406]

31

Pripravljalni in zaključni procesi


Predmet: Pripravljalni in zaključni procesi

Course title: Upstream / Downstream Processes




Semester Semester


Kemijska tehnika Chemical engineering

2. zimski

Autumn



Predavanja Lectures

Seminar Seminar

Sem. vaje Tutorial


work



ECTS

30 30 120 6


Jeziki / Languages:




Prerequisits:

Pojmi in osnovna znanja s področij industrijske stehiometrije, energetske bilance kemijskih sistemov in proizvodnje produktov.

Basic knowledege in the field of industrial stochiometry, energetic balance of chemical systems and production of products.


Osnove industrijskih pripravljalnih in zaključnih procesov za različne vrste produktov.

Načrtovanje in razvoj strategij pripravljalnih in zaključnih procesov; Primerjava pripravljalnih in zaključnih procesov.

Različni separacijski tehnološki postopki (uparjanje, centrifugiranje, konvencionalna in membranska filtracija, postopki obarjanja, kristalizacija, procesna kromatografija, ...) in njihova učinkovitost.

Izhodišča raziskav (case study) in razvoj celotnega procesa.

V okviru laboratorijskih vaj se izvaja superkritična

General introduction to industrial downstream and upstream processes for different products.

Process design and development of downstream processing (upstream versus downstream).

Different separation technological processes (evaporation, centrifugation, conventional and membrane filtration, precipitation processes, crystallization, process chromatography,...) and their effectiveness.

Case studies and development of the complete process.

Laboratory work includes supercritical extraction, antimicrobial activity of extract, micronisation,

32

ekstrakcija, protibakterijsko delovanje ekstrakta, mikronizacija, superkritična kormatografija.

supercritical chromatography.


B. Elvers, S. Hawkins, W. E Russey: Ullmann's encyclopedia of industrial chemistry, izbrana poglavja, Weinheim, Cambridge: Wiley-VCH, 2003.


J. Nielsen, J. Villadsen, G. Liden, Bioreaction Engineering Principles, 2nd ed., Kluwer Academic/Plenum Publishers, 2003.

M. C. Flickinger, Downstream Industrial Biotechnology: Recovery and Purification, Wiley, 2013, ISBN: 978-1-118-13124-4.



- Priprava surovin in obdelava produktov v industriji.

- Pravilna razporeditev produktnih enot za obdelavo (čiščenje) določenega produkta.

- Povezava med pripravljalnimi in zaključnimi procesi.

- Pomembnost čistote produkta v razvoju in načrtovanju v pripravljalnih procesih.

- Obdelava (študij) rezultatov realnih primerov in njihova uporaba za izbiro procesnih pogojev za določeno operacijo.

- Izračun operativnih parametrov za določeno operacijsko enoto pripravljalnega procesa.

- Preparation of raw materials and product processing in industry.

- Appropriate arrangement of unit operations for the processing (purification) of a given type of a product.

- Interplay between upstream and downstream processes.

- Importance of product purity during development and planning of upstream processes.

- Results processing (study) of real examples and their use for the selection of process conditions for specific operation.

- Calculation of operating parameters for a given downstream unit operation process.


Znanje in razumevanje: Zmožnost načrtovanja pripravljalnih in zaključnih procesov za komercialno pomembne substance. Prenesljive/ključne spretnosti in drugi atributi: Vsebina predmeta je povezana z ostalimi predmeti na smeri Kemijska tehnika in podaja znanja, potrebna za lažje razumevanje vsebin, ki so zajete npr. pri predmetu Farmacevtska tehnika.

Knowledge and understanding: The ability to design of upstream / downstream processes for commercially important compounds. Transferable/Key Skills and other attributes: The subject is connected to other subjects on the direction Chemical engineering and gives the knowledge which is necessary for understanding other subjects such as Pharmaceutical technology.



- lectures - laboratory work



Assessment:


- pisni izpit - ustni izpit - laboratorijske vaje

60 30 10


- written examination - oral examination - laboratory work

33


KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010, str. [3]-38.

MARKOČIČ, Elena, ŠKERGET, Mojca, KNEZ, Željko. Polylactide and poly(lactide-co-glycolide) processed with supercritical CO2 for biomedical applications. V: FELTON, Gary P. (ur.). Biodegradable polymers : processing, degradation and applications. Hauppauge, N.Y.: Nova Science Publishers, 2011, str. [517]-543.

KNEZ, Željko, FRITSCH, Markus, SCHULZE, Joachim, LÜTGE, Christoph. Process for the purification of carboxylic acids by subcritical or supercritical fluid chromatography : European patent application no. 2745905 A1, date of publication: 25. 06. 2014 Bulletin 2014/26; appl. no.: 12008534.5, date of filling: 21. 12. 2012. Munich: Europäisches Patentamt: = European Patent Office: = Office européen des brevets, 2014.

KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental applications. Amsterdam: Elsevier, 2014, str. 31-67.

34

Energetski management procesov


Predmet: Energetski management procesov

Course title: Energy Management of Processes




Semester Semester



2. zimski

Autumn



Predavanja Lectures

Seminar Seminar

Sem. vaje Tutorials


work



ECTS

30 30 120 6


Jeziki / Languages:




Prerequisites:

Ni pogojev. None.


Energetske razmere v svetu

Vrste energije, namen uporabe, razlogi za varčevanje

Tehnični in praktični vidiki izkoriščanja virov energije

Aktivni sistemi za izkoriščanje virov energije

Racionalizacija uporabe energije v industriji

Energijske pretvorbe v tehnoloških procesih

Tehnologije za izkoriščanje odpadne toplote in vrednotenje investicij v smislu racionalizacije

Značilni primeri energetskih ukrepov v kemijski procesni industrij

Energetski pregledi

Možni ukrepi za zmanjšanje porabe energije (predlogi izboljšav sistemov oskrbe z energijo)

Analiza ukrepov za zmanjšanje porabe energije

Energy situation in the world

Energy types, purpose, reasons for energy savings

Technical and practical aspect of exploiting energy sources

Active systems for exploitation of energy sources

Rationalization of the use of energy in industry

Energy transformations during technological processes

Technology for exploiting waste heat and evaluating the rationality of investments

Significant examples for measures taken in chemical process industry

Energy revision

Measures taken to reduce the consumption of energy (suggestions to improve the systems for supply of energy)

35

(potrebna investicijska sredstva, prihranki, ekološka presoja, doba vračila, lista ukrepov)

Metode dinamičnega izračuna gospodarnosti energetskih postrojev

Vaje: Študent samostojno reši več praktičnih primerov in izdela krajšo projektno nalogo.

Analysis of measures to reduce consumption of energy (the investment assets needed, savings, ecological evaluation, list of measures)

Methods of dynamic calculation of economic efficiency energy systems

Exercises: Student individually solve the more practical examples and short process design formulation.


Capehart, B. L., Turner, W. C., Kennedy, W. J., Guide to energy management, 6th Edition, 2008.


A. P. Rossiter, B. P. Jones, Energy Management and Efficiency for the Process Industries, AIChE, 2015.

Turner W., Energy management handbook, Fairmont press, Liburn, 2001.

Aldo V da Rosa, Fundamentals of renewable energy processes, academic Press, august 3, 2005.

John Twidell, Renewable energy resources, Taylor&Francis. 2nd edition, December 16, 2005.



Študent se seznani s praktičnimi možnostmi za boljšo energetsko izobrazbo (npr. varčevanje z energijo, večji izkoristki v transformacijah energije) in izkoriščanje obnovljivih virov.

Razvoj strokovnih spretnosti – spretnosti pri skupinskem delu in reševanju problemov.

The student will acquire practical knowledge regarding the energy sector, such as saving the energy, increasing the efficiency while transforming the energy and using the renewable energy sources.

Development of professional skills – skills in team work and problem.



Možnost ocene primerjave količinskih in kakovostnih vplivov ukrepov na rabo energije in na emisije

Kaj je energetski pregled podjetja?

Katere spremembe v energetski porabi so nujne?

Razumevanje osnovnih principov o možnostih izkoriščanja obnovljivih virov energije


Learning how to evaluate and compare the quantitative and qualitative effects of measures taken for the se of energy and emissions

What is power assessment of a factory?

What changes in power use of an enterprise are mandated through an assessment?

Understanding the fundamental principles of the possibility of exploiting renewable energy sources


Sposobnost prenosa teoretičnih spoznanj na manj teoretično okolje in njihova uporaba za določitev primernih energetskih virov in njihove uporabe

Sposobnost spremljanja sprememb, ki nastaja pri izvajanju energetske zasnove in racionalne rabe energije


Ability to transfer theoretical knowledge in less theoretical environment and use of this knowledge to determine energy sources and sensible use of energy sources

Acquiring the knowledge to follow the changes arising when preparing the energy base and when using the energy rationally



predavanja

obravnava študijskih primerov

aktivno skupinsko delo

lectures

field work

active team work

http://cobiss6.izum.si/scripts/cobiss?ukaz=SEAL&mode=5&id=1014241182823280&PF=AU&term=%22Capehart,%20Barney%20L.%22

http://cobiss6.izum.si/scripts/cobiss?ukaz=SEAL&mode=5&id=1014241182823280&PF=AU&term=%22Turner,%20Wayne%20C.,%201942-%22

http://cobiss6.izum.si/scripts/cobiss?ukaz=SEAL&mode=5&id=1014241182823280&PF=AU&term=%22Turner,%20Wayne%20C.,%201942-%22

36



Assessment:


seminarska naloga

teoretični del izpita

računski del izpita Teoretični in računski del tvorita celoto in se preverjata hkrati.

20 30 50


seminar

theoretical part of the exam

calculation part of the exam The theoretical and the calculus part of exam are performed simultaneously.


DOBERŠEK, Danijela, GORIČANEC, Darko. An experimentally evaluated magnetic device's efficiency for water-scale reduction on electric heaters. Energy, ISSN 0360-5442. [Print ed.], Available online 27 September 2014, str. 1-8.

SORŠAK, Marko, ŽEGARAC LESKOVAR, Vesna, PREMROV, Miroslav, GORIČANEC, Darko, PŠUNDER, Igor. Economical optimization of energy-efficient timber buildings: Case study for single family timber house in Slovenia. Energy, ISSN 0360-5442. [Print ed.], Article in Press 2014, str. 1-9.

GORIČANEC, Darko, POZEB, Viljem, TOMŠIČ, Ladislav, TROP, Peter. Exploitation of the waste-heat from hydro power plants. Energy, ISSN 0360-5442. [Print ed.], Available online 22 July 2014, str. 1-6, doi: 10.1016/j.energy.2014.06.106. [COBISS.SI-ID 17986326].

KULČAR, Bojan, GORIČANEC, Darko, KROPE, Jurij. Economy of replacing a refrigerant in a cooling system for preparing chilled water = Remplacement du frigorigene dans un systeme utilisé pour préparer de l'eau glacée : impact financier. International journal of refrigeration, ISSN 0140-7007. [Print ed.], Aug. 2010, vol. 33, iss. 5, str. 989-994.

ŽLAK, Janez, AGREŽ, Marko, DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Rentability of rotary heat regenerator use in ventilating systems = Rentabilnost upotrebe regeneratora topline u ventilacijskom sustavu. Strojarstvo, ISSN 0562-1887, 2010, vol. 52, no. 6, str. 665-671.

37

Sinteza procesov


Predmet: Sinteza procesov

Course title: Process Synthesis




Semester Semester



2. zimski

autumn



Predavanja


Sem. vaje Tutorial




ECTS

30 30 120 6

Nosilec predmeta / Lecturer: Zdravko Kravanja

Jeziki / Languages:




Prerequisites:

Osnovna znanja iz načrtovanja in optimiranja procesov

Basic knowledge of process design and optimization


Osnovni koncepti algoritemskih metod:

predstavitev problema z drevesno in mrežno predstavitvijo,

alternativne formulacije za matematično programiranje,

modeliranje logičnih pogojev in disjunkcij.

Sinteza destilacijskih zaporedij:

linearni model kolon z ostro separacijo,

mešano-celoštevilski model za destilacijska zaporedja,

toplotno integrirana destilacijska zaporedja.

Sinteza reakcijskih omrežij:

koncept dosegljivega območja,

sinteza reakcijskih omrežij s ciljano formulacijo,

sinteza reakcijskega omrežja v celotni procesni shemi.

Basic concepts of algorithmic methods:

Tree and network problem representations.

Alternative mathematical programming formulations.

Modeling of logical constraints and disjunctives.

Synthesis of distillation sequences:

Linear model for sharp split columns.

Mixed-integer linear model for distillation sequences.

Heat integrated distillation sequences.

Reactor network synthesis:

Geometrical concept for attainable region.

Synthesis of reactor networks with a targeting formulation.

Reactor network synthesis in overall process scheme.

Synthesis of overall process schemes:

38

Sinteza celotnih procesnih shem:

definiranje superstrukture: - osnovnih podsistemov, - celotnih procesov,

procesni sintetizer MIPSYN.

Računalniške vaje iz sinteze procesnih sistemov.

Superstructure representation of: - basic subsystems, - overall process schemes.

Process synthesizer MIPSN.

Computer room: synthesis of process systems.


Biegler L.T., I.E.Grossmann and A.W.Westerberg, Systematic Methods of Chemical Process Design, Prentice Hall, New Jersey, 1999.

A. Brooke, D. Kendrick, A. Meeraus, R. Raman, GAMS - A user Guide, Scientific Press, GAMS Development Corporation, 2015. http://www.gams.com/dd/docs/bigdocs/GAMSUsersGuide.pdf



Cilj je podati podrobnejše znanje o sintezi procesov in procesnih podsistemov.

The aim is to give knowledge of synthesis of process schemes and their subsystems in more details.



Znanje in razumevanje: Obvladovanje teorije in aplikacij matematičnega programiranja (optimiranja) pri sintezi kemijskih in biokemijskih procesov ter njihovih podsistemov.

Knowledge and Understanding: Understand theory and have knowledge of some practical applications of mathematical programming in synthesizing (bio)chemical processes and their subsystems.

Prenesljive/ključne spretnosti in drugi atributi: Imeti razumevanje o vplivu sinteznih rešitev na varno, okolju prijazno in ekonomsko učinkovito delovanje kemijskih in biokemijskih procesov.

Transferable/Key Skills and other attributes: To have an understanding of the impact of synthesis solutions on safe, environmentally benign and economically effective operation of chemical and biochemical processes.


Predavanja, seminar in računalniške vaje. Samostojno delo študenta.

Lectures, seminar work, and computer practice. Self-learning.



Assessment:

Izpit je opravljen, če sta pozitivno opravljeni naslednji obveznosti:

seminarska naloga

predstavitev seminarske naloge

70 30


Seminar work

Presentation of the seminar work


AHMETOVIĆ, Elvis, KRAVANJA, Zdravko. Simultaneous optimization of heat-integrated water networks involving process-to-process streams for heat integration. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2014, vol. 62, iss. 1, str. 302-217, doi: 10.1016/j.applthermaleng.2013.06.010.

NEMET, Andreja, KLEMEŠ, Jiri, KRAVANJA, Zdravko. Designing a Total Site for an entire lifetime under fluctuating utility prices. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], Available online 18 July 2014, vol. , str. 1-24, doi: 10.1016/j.compchemeng.2014.07.004.

ČUČEK, Lidija, MARTÍN, Mariano, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Multi-period synthesis of optimally-integrated biomass and bioenergy supply network. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], 4 Jul. 2014, vol. 66, str. 57-70, doi: 10.1016/j.compchemeng.2014.02.020.

KRAVANJA, Zdravko, ČUČEK, Lidija. Multi-objective optimisation for generating sustainable solutions considering total effects on the environment. V: DUIĆ, Neven (ur.). Sustainable development of energy, water and environment systems, (Applied Energy, ISSN 0306-2619, Vol. 101, (2012)). Oxford: Elsevier, cop. 2012, vol. 101, str. 67-80, doi:

39

10.1016/j.apenergy.2012.04.025.

ČUČEK, Lidija, KLEMEŠ, Jiri, KRAVANJA, Zdravko. A Review of Footprint analysis tools for monitoring impacts on sustainability. Journal of cleaner production, ISSN 0959-6526. [Print ed.], Oct. 2012, vol. 34, str. 9-20, doi: 10.1016/j.jclepro.2012.02.036.

40

Procesne surovine za bio in prehrambeno industrijo


Predmet: Procesne surovine za bio in prehrambeno industrijo

Course title: Process Raw Materials for Bio and Food Industry




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

30 30 120 6

Nosilec predmeta / Lecturer: Zoran Novak

Jeziki / Languages:




Prerequisites:

Potrebno je znanje iz separacijske tehnike, mikrobiologije, biokemije, biokemijske tehnike, industrijske mikrobiologije in biotehnologije.

Knowledge of separation processes, microbiology, biochemistry, biochemical engineering, industrial microbiology and biotechnology is needed.

Vsebina:


- Uvod - Prevzem in skladiščenje surovin. - Priprava surovin (čiščenje, sortiranje, luščenje). - Surovine v biotehnoloških procesih za

proizvodnjo živil in krmil živalskega in rastlinskega izvora.

- Surovine v fermentacijski industriji. - Biomasa - biološka surovina, proizvedena iz

rastlin in živali. - Surovine za proizvodnjo biomase in njihova

priprava (surovine v trdnem, tekočem in plinastem stanju).

- Mikroorganizmi za proizvodnjo biomase. - Procesi in aparature. - Primeri.

Laboratorijske vaje iz področja kontrole surovin v bio industriji.

- Introduction - Raw materials in food industries - Storage of raw materials. - Preparation of raw materials. - Raw materials of animal and vegetal source in

biotechnological processes for production of food and feeding stuff.

- Raw materials in fermentation industry. - Biomass from plant and animal origin. - Raw materials for biomass production and their

preparation. - Microorganisms for biomass production. - Processes and apparatus. - Examples.

Laboratory work on the case of raw material control in bio-industry.

41


P. Fellows, Food Processing Technology: Principles and Practice, 3rd ed., CRC Press, USA, 2009.


S. Gad, Handbook of Pharmaceutical Biotechnology Pharmaceutical Development, Wiley-VCH, Weinheim, 2007.

M. C. Flickinger, Upstream and Downstream Industrial Biotechnology, 3V Bundle, Wiley, ISBN: 978-1-118-13125-1, 2014.




Razumevanje tehnik priprave surovin v industrijske namene.

Understanding of techniques for raw materials preparation in industrial use.



Znanje in razumevanje: Optimalna izbira surovin glede na zahteve nadaljne predelave oz. biosinteze ter ekonomike proizvodnje.

Knowledge and Understanding: Optimal selection of raw materials, considering further application or biosynthesis and economic of the process.

Prenesljive/ključne spretnosti in drugi atributi: Predmet se dopoljnjuje z ostalimi vsebinami na smeri Biokemijska tehnika.

Transferable/Key Skills and other attributes: The subject is related to the other subjects on the study feild Biochemical engineering.




Lectures in lecture room, equipped with audio-visual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on a selected case.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje (dnevnik, kolokvij) - pisni izpit - ustni izpit

20 60 20

Student has to pass successfully the following obligations: - laboratory work (report, colloquium) - written examination - oral examination


KNEZ, Željko, AIONICESEI, Elena, NOVAK, Zoran, KNEZ HRNČIČ, Maša. Processing polymeric biomaterials using supercritical CO[sub]2. Chemieingenieurtech., 2011, vol. 83, no. 9, str. 1371-1380. [COBISS.SI-ID 15347734]

VERONOVSKI, Anja, NOVAK, Zoran, KNEZ, Željko. Synthesis and use of organic biodegradable aerogels as drug carriers. Journal of biomaterials science, Polymer edition, ISSN 0920-5063, 2012, vol. 23, no. 7, str. 873-886., doi: 10.1163/092050611X566126. [COBISS.SI-ID 15819286],

VERONOVSKI, Anja, TKALEC, Gabrijela, KNEZ, Željko, NOVAK, Zoran. Characterisation of biodegradable pectin aerogels and their potential use as drug carriers. Carbohydrate polymers, ISSN 0144-8617. [Print ed.], 26 Nov. 2014, vol. 113, str. 272-278, doi: 10.1016/j.carbpol.2014.06.054. [COBISS.SI-ID 18000150]

HE, Li, ZHANG, Xiaofei, XU, Honggao, XU, Chao, YUAN, Fang, KNEZ, Željko, NOVAK, Zoran, GAO, Yanxiang. Subcritical water extraction of phenolic compounds from pomegranate (Punica granatum L.) seed residues and investigation into their antioxidant activities with HPLC-ABTS assay. Food and bioproducts processing, ISSN 0960-3085, Apr. 2012, vol. 90, iss. 2, str. 215-223, doi: 10.1016/j.fbp.2011.03.003. [COBISS.SI-ID 14920470]


http://dx.doi.org/10.1163/092050611X566126


http://dx.doi.org/10.1016/j.carbpol.2014.06.054


http://dx.doi.org/10.1016/j.fbp.2011.03.003


42

Sodobne procesne tehnike v živilstvu


Predmet: Sodobne procesne tehnike v živilstvu

Course title: Modern Process Operations in Food Engineering




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

30 30 120 6

Nosilec predmeta / Lecturer: Mojca Škerget

Jeziki / Languages:

Predavanja / Lecture: slovenski/Slovene

Vaje / Tutorial: slovenski/Slovene


Prerequisits:

Osnovno znanje prenosnih pojavov (prenos toplote in snovi) in osnovnih procesnih operacij.

Basic knowledge on transport phenomena (heat and mass transfer) and unit operations.

Vsebina:


Reologija živilskih izdelkov:osnovni pojmi, reološka klasifikacija fluidov, reološki modeli, vpliv temperature in vpliv koncentracije na viskoznost.

Termične lastnosti živilskih izdelkov: toplotna prevodnost, specifična toplotna kapaciteta, gostota, termična difuzivnost.

Načrtovanje postopkov termičnega procesiranja živil – sterilizacija: hitrost termične inaktivacije, procesiranje konzerviranih produktov, aseptični postopek procesiranja tekočin.

Načrtovanje postopkov konzerviranja živil s hlajenjem: zamrzovanje, temperatura zmrzišča, termične lastnosti zamrznjenih živil, čas zamrzovanja, načrtovanje zamrzovalnega sistema, hlajenje in hladilni sistemi.

Sodobni tehnološki postopki v predelavi živil: priprava snovi, membranske operacije,

Rheology of food products: fundamentals, rheological classification of food products, rheological models, influence of temperature and concentration on viscosity.

Thermal properties of food: thermal conductivity, specific heat, density, thermal diffusivity.

Thermal processing of foods: thermal death rate, treatment of canned products, aseptic processing of liquid products.

Food preservation by cooling: freezing, freezing temperature, thermal properties of frozen foods, freezing time, design of freezing systems, refrigeration and refrigeration systems.

Emerging technologies for food processing: Preparation of material, membrane processes, pasterization and sterilization by high pressure processing, encapsulation technologies for active food ingredients and functional foods,

43

pasterizacija in sterilizacija z visokimi tlaki, enkapsulacija komponent in vgradnja v funkcionalna živila, pridobivanje praškastih produktov s superkritičnimi fluidi.

vpliv procesiranja na kvaliteto prehrambenih izdelkov: kemijske spremembe pri procesiranju in načrtovanje končnih produktov.

pakiranje izdelkov, permeabilnost, pokvarljivost in rok trajanja: namen, nivoji pakiranja in embalažni materiali, načini pakiranja, prepustnost embalažnih materialov za pline in paro.

Proizvodne tehnologije izbranih skupin prehrambenih izdelkov.

Laboratorijske vaje: - Reološke lastnosti živilskih izdelkov, - Enkapsulacija aktivnih komponent in testi

stabilnosti.

production of powderous products by supercritical fluid technologies.

Effects of food processing on quality of foods: chemical changes during processing and design of products with tailor-made properties;

Food packing, permeability and Shelf-Life: functions of packing, levels of packing and materials, types of packing, permeability for gasses and vapour.

Procesing technology of selected food product groups.

Laboratory work:

Rheological properties of foods,

Encapsulation of active compounds and stability tests.


A. Ibarz, G.V. Barbosa-Cánovas, Unit Operations in Food Engineering, CRC Press, Boca Raton, 2003.

Emerging technologies for food processing, Ed.: D.-W. Sun, Elsevier Ltd., 2005.


Food Processing Handbook, Ed.: J. G.Brennan, Wiley-VCH Verlag GmbH, Weinheim, 2006.

Food processing Principles and Applications, Eds: J. S. Smith, Y. H. Hui, Blackvell Publishing, 2004

P. Fellows: Food Processing Technology: Principles and Practice, 2nd ed., Woodland Publishing; 2000.



Seznaniti študente s sodobnimi tehnološkimi postopki in principi in novimi tehnologijami, ki se uporabljajo za proizvodnjo prehrambenih izdelkov in sodobnih produktov, ki so narejeni po meri potrošnika. Študent bo poznal uporabnost različnih metod za različne skupine izdelkov in vpliv procesiranja na kvaliteto izdelka. Znal bo načrtovati in optimirati posamezne procesne operacije. Poznal bo zahteve in ukrepe, ki so potrebni za zagotavljanje varnosti živil v proizvodnji in prometu.

The objective is to introduce the student to the operations and principles in food processing, emerging technologies and production of products with tailor-made properties. The students should be able to evaluate different types of unit operations in connection with treatment of different types of foods and the effects of processing on quality of foods. They should be able to design and optimize specific process operations. They should know the measures and arrangements which are necessary to assure food safety in production process and in retail.



sodobnih operacij in principov procesiranja prehrambenih izdelkov;

vplivov procesiranja na kvaliteto izdelkov;

načrtovanje produktov po meri potrošnika;

načrtovanje in optimiranje posameznih procesnih operacij;

zahtev in ukrepov, ki so potrebni za


operations and principles of food processing;

effects of processing on quality of foods;

design of products with tailor-made properties;

design and optimization of process operations;

measures and arrangements necessary to assure food safety in production process and in retail.

44

zagotavljanje varnosti živil v proizvodnji in prometu.

Prenesljive/ključne spretnosti in drugi atributi: - znanja za inovativno delo v prehrambeni

industriji - razvoj novih produktov

Transferable/Key Skills and other attributes: - Achieving knowledge for inovative work in food

industry - Development of new products


Predavanja

Reševanje problemov

Laboratorijske vaje

Lectures

Solving problems

Laboratory work



Assessment:

Način (pisni izpit, ustno izpraševanje, naloge, projekt) Ustni izpit Pisni izpit Laboratorijske vaje

40 30 30

Type (examination, oral, coursework, project): Oral examination Written examination Labor work


RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from sunflower seeds with subcritical water. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2015, vol. 166, str. 316-323, doi: 10.1016/j.foodchem.2014.06.025. [COBISS.SI-ID 17908502],

PAVLOVIČ, Irena, KNEZ, Željko, ŠKERGET, Mojca. Hydrothermal reactions of agricultural and food processing wastes in sub- and supercritical water : a review of fundamentals, mechanisms, and state of research. Journal of agricultural and food chemistry, ISSN 0021-8561, 2013, vol. 61, no. 34, str. 8003-8025, doi: 10.1021/jf401008a. [COBISS.SI-ID 17077526],

KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010, str. [3]-38. [COBISS.SI-ID 14789910]

VATAI, Tünde, ŠKERGET, Mojca, KNEZ, Željko. Extraction of phenolic compounds from elder berry and different grape marc varieties using organic solvents and/or supercritical carbon dioxide. Journal of food process engineering, ISSN 0145-8876, 2009, vol. 90, iss. 2, str. 246-254. http://dx.doi.org/10.1016/j.jfoodeng.2008.06.028, doi: 10.1016/j.jfoodeng.2008.06.028. [COBISS.SI-ID 12483094],

MANDŽUKA, Zoran, ŠKERGET, Mojca, KNEZ, Željko. High pressure micronization of tristearate. Journal of the American Oil Chemists' Society, ISSN 0003-021X, Feb. 2010, vol. 87, no. 2, str. 119-125, doi: 10.1007/s11746-009-1482-4. [COBISS.SI-ID 13787670],

ŠKERGET, Mojca. Separacija naravnih učinkovin in formulacija produktov: zaključno poročilo o rezultatih znanstvenoraziskovalnega sodelovanja. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2012. [8] f. [COBISS.SI-ID 15903510]

45

Genomika v biomedicinski tehnologiji


Predmet: Genomika v biomedicinski tehnologiji

Course title: Genomics in Biomedical Technology




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

30 30 120 6

Nosilec predmeta / Lecturer: Uroš Potočnik

Jeziki / Languages:




Prerequisites:

Pogojev ni. None.


Osnove toksikologije in farmakogenomike tehnologije v genomiki: nanotehnologija, mikromreže (biočipi), tehnologija za avtomatsko gensko tipizacije enonukleotidnih polimorfizmov v celotnem genomu (SNPov), sekvenciranje celotnih genomov, Maldi-TOF, 2-D elektroforeza genomika in odkrivanje novih zdravil genomika raka asociacijske študija za odkrivanje novih genov povezanih s kompleksnimi boleznimi (avtoimunske bolezni, rak, astma, sladkorna…) funkcijska genomika transkriptomika fiziološka genomika primerjalna (komparativna ) genomika mikrobna genomika proteomika bioinformatika genetski testi v diagnostiki bolezni

Basics toxicology and pharmacogenomics genomic technologies: nanotechnology, microarrays (Biochips), whole genome genotyping of Single nucleotide Polymorphisms (SNPs), Maldi-TOF, 2-D electrophoresis genomics in drug discovery cancer genomics disease association study in common complex diseases (autoimmune diseases, cancer, asthma, diabetes…) functional genomics transcriptomics physiological genomics comparative genomics genomics of microorganisms proteomics bioinformatics statistical genetics and disease association analysis Genetics in diagnosis

46

genska terapija etika v genomiki Hibridizacije nukleinskih kislin, mikromreže Pomnoževanje molekul DNA v pogojih in vitro (PCR), Sekvenciranje DNA Dvohibridni kvasni sistem za določanje interakcij protein-protein Spreminjanje genov - in vitro mutageneza, živalski modeli z izbitim genom-pomen v funkcijski genomiki in bolezenskih modelih Preprečevanje izražanja genov - protismiselna tehnologija, siRNA Kloniranje človeških genov, reproduktivno kloniranje sesalcev, terapevtsko kloniranje Transgene rastline in živali Genska tehnologija pri proizvodnji zdravil in diagnostičnih sredstev Zakonodaja in varnostni predpisi za delo z genetsko spremenjenimi organizmi Vloga rekombinantne DNA tehnologije v sodobni družba: etični, sociološki in ekonomski vidiki Laboratorijske vaje:

Priprava genomskih in cDNA knjižnic

Kloniranje: Gostiteljski organizmi, vektorji, strategije kloniranja v prokariontske in evkariontske orgnizme, transformacija in transfekcija, ekspresija rekombinantnih proteinov

Preiskava DNA za tipizacijo tkiv in za osebno identifikacijo

Gene therapy Ethics in genomics Hybridization of nucleic acids, DNA micro arrays Polymerase DNA reaction (PCR), DNA sequencing Yeast two-hybrid system for identification of protein-protein interaction Site directed mutagenesis, knock-out technology and animal models-the role in functional genomics and animal disease models Silencing gene expression: RNAi, antisense RNA technology Cloning human genes, reproductive cloning of mammalians, therapeutic cloning Transgenic plants and animals Gene technology in drug production and diagnostics Low regulations and safety precautions for research and applications of genetic modified organisms Recombinant DNA technology and society: ethic and social economic issues Laboratory work:

preparation of genomic and cDNA libraries

Cloning: Host organisms, DNA cloning vectors, cloning strategy in eukaryotes and prokaryotes, transformation and transfect ion, expression of recombinant proteins

DNA fingerprinting in forensics


Thompson & Thompson: Genetics in Medicine, W.B.Saunders Company., 7the ISBN 0-7216-0244-4 and 7th ed. ISBN: 9781416030805, 2007.

Tom Strachan, Judith Goodship & Patrick Chinnery, Genetics and genomics in medicine, Garland Sc, ISBN 9780815344803, 2014.


Bernard R. Glick, Jack J. Pasternak: Principles and applications of recombinant DNA, 3rd edition, ASM Press, Washington, 2003.

Philip Benfey: Genomics, Prentice Hall, Inc., New Jersey , 2005.



Študenti bodo spoznali osnovne tehnike in uporabo rekombinantne DNA tehnologije v raziskavah in v praksi.

Students will be provided with basic techniques and applications of recombinant DNA technology in research and industry.


Znanje in razumevanje: tehnike in principi kloniranja DNA in ostalih

pristopov v rekombinanti DNA tehnologiji uporaba rekombinantne DNA tehnologije v

raziskavah in praksi


techiques and principles of DNA cloning and other recombinant DNA technology

applications of recombinant DNA technology in research and industry

Prenesljive/ključne spretnosti in drugi atributi: Transferable/Key Skills and other attributes:

47


Predavanja

Seminarske vaje

Laboratorijske vaje

Lectures

Tutorial

Laboratory work



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni izpit ustni izpit

60 40

Student has to pass successfully the following obligations: writen examination oral examination


JOSTINS, Luke, MITROVIČ, Mitja, POTOČNIK, Uroš. Host-microbe interactions have shaped the genetic architecture of inflammatorybowel disease. Nature (Lond.), 2012, vol. 491, no. 7422, str. 119-124, doi: 10.1038/nature11582. [COBISS.SI-ID 512230968],

LIU, Jimmy Z, MITROVIČ, Mitja, POTOČNIK, Uroš. Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nat Genet, 2013, 79 str., ilustr. http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2616.html, doi: 10.1038/ng.2616. [COBISS.SI-ID 512280376],

RIVAS, Manuel A, MITROVIČ, Mitja, POTOČNIK, Uroš. Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nat Genet, 2011, vol. 43, no. 11, str. 1066-1073, doi: 10.1038/ng.952. [COBISS.SI-ID 15421974],

ALMOUZNI, Geneviève, GRGUREVIČ, Neža, MAJDIČ, Gregor, POTOČNIK, Uroš, ILAŠ, Janez, et al. Relationship between genome and epigenome - challenges and requirements for future research. BMC genomics, ISSN 1471-2164, 2014, vol. 15, no. 487, str. 1-7. http://www.biomedcentral.com/1471-2164/15/487, doi: 10.1186/1471-2164-15-487. [COBISS.SI-ID 512412216],

REPNIK, Katja, POTOČNIK, Uroš. Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene. J Gastroenterol, 2011, vol. 46, no. 9, str. 1081-1091, doi: 10.1007/s00535-011-0426-6. [COBISS.SI-ID 15110422].

48

Okoljska biotehnologija


Predmet: Okoljska biotehnologija

Course title: Environmental Biotechnology



Letnik Academic

year

Semester Semester


2. zimski

Autumn

Vrsta predmeta / Course type: Izbirni / Elective


Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6


Jeziki / Languages:




Prerequisites:

Potrebno je znanje iz mikrobiologije, biokemije, industrijske mikrobiologije in separacijske tehnike.

Knowledge of microbiology, biochemistry, industrial microbiology and separation processes is needed.

Vsebina:


Odpadne vode (komunalne, industrijske, lastnosti). Čiščenje odpadnih vod z aerobnimi procesi (cilji in omejitve, vrste procesov). Čiščenje odplak z anaerobnimi procesi (biologija formiranja metana, vrste procesov, procesni pogoji). Biološko čiščenje odpadnega zraka in razgradnja trdnih odpadkov. Vzorčevanje, priprava vzorcev, ekstrakcija celic, detekcija funkcionalnih aktivnosti v vzorcih iz okolja. Bioremediacija. Kompostiranje. Bioinsekticidi.

Wastewater (communal sewage, industrial effluents, properties of the substrate wastewater). Purification of wastewater by aerobic processes (aims and limitations, purification processes). Purification of effluents by anaerobic processes (biology of formation of methane, technical processes, process conditions). Biological purification of waste air and degradation of solid wastes. Sampling, sample preparation, cell extraction, detection of functional activity in environmental samples. Bioremediation. Composting. Bioinsecticides.

49

Laboratorijske vaje iz področja detekcije funkcionalnih aktivnosti v vzorcih iz okolja.

Laboratory work from the field of detection of functional activity in environmental samples.


G. M. Evans, J. C. Furlang, Environmental Biotechnology: Theory and Applications, 2nd ed., Wiley Weinheim, 2010.

R. H. Baltz, A. L. Demain, J. E. Davies, Manual of Industrial Microbiology and Biotechnology, 3rd ed., ASM Press, Washington, D.C., 2010.


G. Lear, G. D. Lewis, Microbial Biofilms: Current Research and Applications, Caister Academic Press, New Zealand, 2012.



Uporaba bioloških snovi (organizmov ali njihovih delov), skupaj s kemijskimi, fizikalnimi in inženirskimi procesi, za zaščito in obnovo okolja.

Application of biological agents (organisms or their components), along with chemical, physical and engineering processes to protect and restore the environment.



Znanje in razumevanje: Poznavanje vloge »tehnične mikrobiologije« pri razvoju procesov čiščenja odpadnih vod in zraka ter tehnologij z uporabo bioloških sistemov za katalizo razpada ali transformacije raznih kemikalij v manj škodljive oblike.

Knowledge and Understanding: Understanding of the role of »technical microbiology« in the development of waste water and air purification processes and technologies that use biological systems to catalyze the destruction or transformation of various chemicals to less harmful forms.

Prenesljive/ključne spretnosti in drugi atributi: Predmet se dopoljnjuje z ostalimi vsebinami smeri Biokemijska tehnika.





Lectures in a lecture room, equipped with audio-visual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on a selected case.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje - ustni izpit

30 70

Student has to pass successfully the following obligations: - laboratory work - oral examination

50


LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The

Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SI-

ID 16864790]

ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 0896-

8446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462]

KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN

0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406]

THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology,

ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222]

KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca. Industrial applications of supercritical fluids : a review. Energy, ISSN 0360-5442. 2014, 1-9,

doi: 10.1016/j.energy.2014.07.044. [COBISS.SI-ID 18010134]

51

Priprava in čiščenje vod


Predmet: Priprava in čiščenje vod

Course title: Water Conditioning and Treatment




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Marjana Simonič

Jeziki / Languages:




Prerequisites:

Splošno znanje iz anorganske in analizne kemije General knowledge of Inorganic and Analytical Chemistry


Kemijska sestava in lastnosti vod: - pitnih - odpadnih

Evropska zakonodaja

Glavni onesnaževalci vod: težke kovine, pesticidi, PCB, motilci endokrinega sistema, antibiotiki

Mehansko in kemijsko čiščenje pitnih vod

Čiščenje komunalne odpadne vode (primarno, sekundarno, terciarno čiščenje)

Čiščenje industrijske odpadne vode

Napredni postopki čiščenja z membranami in ozonom z različnimi kombinacijami (UV, H2O2, katalizatorji)

Seminarska naloga: študentje samostojno obdelajo določen problem s področja čiščenja komunalnih in industrijskih odpadnih vod.

Chemical Water Characteristics - drinking water - wastewater

European Legislation

Main Water Pollutants: heavy metals, pesticides, PCB, endocrine disruptors, antibiotics

Mechanical and Chemical drinking water treatment

Municipal wastewater treatment (primary, secondary, tertiary treatment)

Industrial wastewater treatment

Advanced water treatment: membrane or using ozone in combination with UV irradiation, H2O2, catalysts

Seminar work: Students independently solve problems in the field of the municipal or industrial wastewater treatment and discuss the solutions.

52


Roš M., Simonič M., Šostar-Turk S., Priprava in čiščenje vod, Maribor: Fakulteta za strojništvo (Tiskarna tehniških fakultet), 2005.


Manahan S.E., Environmental Chemistry, 8th edition, CRC Press USA, 2005.

Wastewater Engineering, Treatment and Reuse, 4th edition. Mc Graw Hill Co, 2003.



Spoznati pomembnost priprave vod Spoznati fizikalno-kemijske tehnike priprave in čiščenja vod Osvojiti napredne tehnike čiščenja Sposobnost predlagati najprimernejšo tehnologijo čiščenja Sposobnost izboljšanja obstoječih tehnologij čiščenja vod Sposobnost preliminarnega načrtovanja naprav

To acquaint with water conditioning Understanding the physico-chemical techniques of water conditioning and treatment To acquaint advanced techniques of water treatment Ability to propose the solution for the best water treatment method Understanding of how to improve the existing technologies for water treatment Ability to design the treatment plants


Razumevanje priprave vod Razumevanje fizikalno-kemijskih tehnik čiščenja vod Napredne tehnike čiščenja Sposobnost predlagati najprimernejšo tehnologijo čiščenja Sposobnost izboljšanja obstoječih tehnologij čiščenja vod

Understanding of water treatment Understanding the physico-chemical techniques of water treatment Advanced techniques of water treatment Ability to propose the solution for the best water treatment method Ability to improve the existing technologies for water treatment

Prenesljive/ključne spretnosti in drugi atributi: - osvojiti znanje za dobro delo v praksi - pripraviti pisna poročila in drugo dokumentacijo, - pisno in ustno komunicirati o problematiki.

Transferable/Key Skills and other attributes: - achieving knowledge for good praxtice in

industry, - prepare written reports - discuss the problem.



predavanja, seminarska naloga, ustni zagovor

Lectures, Seminar work, Oral examinations



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: ustni izpit seminarska naloga aktivno delo na predavanjih

60 30 10

Student has to pass successfully the following obligations: oral examination seminar work active work during lectures

53


TEPUŠ, Brigita, SIMONIČ, Marjana, PETRINIĆ, Irena. Comparison between nitrate and pesticide removal from ground water using adsorbents and NF and RO membranes. Journal of hazardous materials, ISSN 0304-3894. [Print ed.], 2009, vol. 170, iss. 2/3, str. 1210-1217.

PETROVIČ, Aleksandra, SIMONIČ, Marjana. The efficiency of a membrane bioreactor in drinking water denitrification. Chemical industry & chemical engineering quarterly, ISSN 1451-9372, Online first 2014, vol. , no , str. 1-17.

KRIŽAN, Janja, MURIĆ, Arnela, PETRINIĆ, Irena, SIMONIČ, Marjana. Recent developments in membrane treatment of spent cutting-oils: a review. Industrial & engineering chemistry research, ISSN 0888-5885. [Print ed.], 2013, vol. 52, no. 23, str. 7603-7616.

KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN 1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249.

54

Nutracevtiki


Predmet: Nutracevtiki

Course title: Nutraceuticals




Semester Semester


2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6


Jeziki / Languages:




Prerequisites:

Pogojev ni. None.


prosti radikali in vloga antioksidantov v bioloških sistemih.

identifikacija naravnih spojin z antioksidativnim, antimikotičnim ali farmakološkim učinkom: vitamini, karotenoidi, n-3 poli nenasičene maščobne kisline, fenolne spojine, lipojska kislina, terpenoidi, steroidi, alkaloidi,...

naravni viri ter postopki izolacije in koncentriranja učinkovin: ekstrakcija, kromatografija,...

vpliv učinkovine na zdravje ter na pojav boleznini in možnosti zdravljenja.

metode določanja antioksidacijskega potenciala: in vitro testiranja (Rancimat test, peroksidno število, anizidinsko število, metoda s standardom TROLOX, BCB test (beta-carotene bleaching test), ORAC test (oxygen radical absorbance capacity), DPPH test (free radical

Free radicals and the role of antioxidants in biological systems;

identification of substances with antioxidative, antimicotic or pharmacological activity (vitamins, carotenoids, n-3 polyunsaturated fatty acids, phenolic compounds, Lipoic acid, terpenoids, steroids, alkaloids,...);

natural sources and isolation and concentration methods (extraction, chromatography,…);

influence of substances on health and occurrence of sickness, disease prevention;

methods for testing antioxidative activity: in vitro tests (Rancimat test,peroxide value, anisidine value, method with the standard TROLOX, BCB test (beta-carotene bleaching test), ORAC test (oxygen radical absorbance capacity), DPPH test (free radical scavenging capacity), test with the radical DMPD, determining the inhibition of human LDL,…),

55

scavening capacity), test s pomočjo radikala DMPD, določanje inhibicije oksidacije človeškega LDL, ....), biomarkerji oksidativnega stresa in vivo.

Vaje: laboratorijsko delo na izbranem primeru, uporaba tehnik za izolacijo in koncentriranje nutracevtika in testiranja aktivnosti in vitro.

oxidative stress biomarkers in vivo. Labor work: laboratory work on selected case, isolation and concentration of nutraceuticals, in vitro activity tests.


Handbook of Nutraceuticals and Functional Foods, R. E. C. WILDMAN (Ed.), 2nd Ed., CRC Press, Taylor & Francis Group, Boca Raton 2007.

K. Kramer, P.-P. Hoppe, L. Packer, eds., Nutraceuticals in Health and Disease Prevention. Marcel Dekker, Inc. New York, 2001.


D. Armstrong, ed., Oxidative Stress Biomarkers and Antioxidant Protocols. Humana Press Inc., New Jersey, 2002.

J. Buttriss, M. Saltmarsh, eds., Functional foods II: claims and evidence, Cambridge: Royal Society of Chemistry, 2000.

E. Cadenas, L. Packer, Handbook of Antioxidants, 2nd ed., Marcel Dekker, Inc. New York, 2002. Cilji in kompetence:


Spoznati naravne produkte, ki pozitivno vplivajo na človeško zdravje (nutracevtiki), metode njihove izolacije, področja uporabe, kot tudi njihove vplive na zdravje in testne metode.

To recognize natural products, which have positive influence on human health (nutraceuticals), the isolation methods, possible areas of application, as well as their influence on the health and test methods.



Vrst, virov, metod pridobivanja, lastnosti in delovanje naravnih bioaktivnih komponent z antioksidativnim, antimikrobiološkim in farmakološkim učinkom za uporabo v prehrambni, kozmetični, predvsem pa v farmacevtski oziroma fitofarmacevtski industriji;

In vitro in in vivo analiznih metod za testiranje antioksidacijskega potenciala


Types, sources, separation methods, properties and activity of natural bioactive compounds with antioxidative, antimicrobiological and pharmacological activity for the use in food, cosmetic and especially in pharmaceutical or phytopharmaceutical industry;

In vitro and in vivo analytical methods for testing antioxidative potential.


znanja za inovativno delo v prehrambni, kozmetični, predvsem pa v farmacevtski oziroma fitofarmacevtski industriji.


Achieving knowledge for inovative work in food, cosmetic and especially in pharmaceutical or phytopharmaceutical industry.



Predavanja,

Laboratorijsko delo na izbranem primeru.

Lectures,

Laboratory work on selected case.

56



Assessment:


ustni izpit

projektno poročilo

50 50


Oral examination

Project report


OMAN, Miha, ŠKERGET, Mojca, KNEZ, Željko. Application of supercritical fluid extraction for the separation of nutraceuticals and other phytochemicals from plant material. Macedonian journal of chemistry and chemical engineering, ISSN 1857-5552, 2013, vol. 32, no. 2, str. 183-226. [COBISS.SI-ID 17365014]

ĐILAS, Sonja, KNEZ, Željko, ČETOJEVIĆ-SIMIN, Dragana, TUMBAS, Vesna, ŠKERGET, Mojca, ČANADOVIĆ-BRUNET, Jasna, CETKOVIC, Gordana. In vitro antioxidant and antiproliferative activity of three rosemary (Rosmarinus officinalis L.) extract formulations. International journal of food science & technology, ISSN 0950-5423. [Print ed.], 2012, vol. 47, iss. 10, str. 2052-2062, doi: 10.1111/j.1365-2621.2012.03069.x. [COBISS.SI-ID 16125206],

RUŽIĆ, Iva, ŠKERGET, Mojca, KNEZ, Željko. Potential of phenolic antioxidants. Acta chimica slovenica, ISSN 1318-0207. [Tiskana izd.], 2010, vol 57, no. 2, str. 263-271. [COBISS.SI-ID 14214678].

RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from sunflower seeds with subcritical water. Food chemistry, 2015, vol. 166, str. 316-323. [COBISS.SI-ID 17908502].

ŠKERGET, Mojca. Separacija in koncentriranje naravnih učinkovin : znanstveno tehnološko sodelovanje z Republiko Madžarsko, 2008-2009 = Separation and concentration of active compounds : Slovenia-Hungary cooperation in science and technology, 2008-2009. Maribor: Fakulteta za kemijo in kemijsko tehnologijo; Budapest: Corvinus University of Budapest, Department of food Engineering, 2010. [5] f. [COBISS.SI-ID 15903254]

ŠKERGET, Mojca, MAJHENIČ, Lucija, BEZJAK, Miran, KNEZ, Željko. Antioxidant, Radical Scavenging and Antimicrobial Activities of Red Onion (Allium cepa L) Skin and Edible Part Extracts. Chemical and biochemical engineering quarterly, ISSN 0352-9568, 2009, vol. 23, no. 4, str. 435-444, ilustr. [COBISS.SI-ID 13799190]


57

Management inoviranja


Predmet: Management inoviranja

Course title: Innovation Management




Semester Semester


2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Dušan Klinar

Jeziki: Languages:

Predavanja / Lecture: slovensko / Slovene

Vaje / Tutorial: slovensko / Slovene


Prerequisites:

Pogojev ni. None.

Vsebina:


- Osnove inoviranja in inovacij - Povezave sistema inoviranja in sistema

kakovosti - Stategije in inoviranje - Potreba po raziskovanju in razvoju (RiR) - Management RiR (organiziranje, izvajanje,

nadzor in metrika) - Storitve in RiR - Etična vprašanja RiR - Odnosi RiR z zunanjim in notranjim okoljem - Izhodišča, pomen, in umestitev razvoja novih

produktov (RNP) - Pregled razvoja zamisli o RNP - Modeli in procesi RNP - Management RNP

Seminarske vaje:

- Obravnava primera dobre prakse - Analiza primera in primerjave

- Fundamentals and theory of Innovation - Relationship among Innovation and quality

systems - Strategy and Innnovation - Why Research and Development (R&D) - Management of R&D (organization,

implementation, controling and metrics) - Service R&D - Ethical considerations of R&D - Integration R&D in environment and

organization - Basics of the New Product Development (NPD)

process - Idea generation for NPD - Concepts and processes of the NPD - NPD Management

Tutorial: - Cases of good practise

58

- Program RNP - Case analysis and bench marking - NPD project


Borut Likar, O inovativnosti slovenske predelovalne in izbranih storitvenih dejavnosti, Univerza na Primorskem, Fakulteta za management Koper, 2014, izbrana poglavja.

Peter Fatur, Borut Likar, Ustvarjalnost zaposlenih za inovativnost podjetja: sistemski vidiki managementa idej kot gradnika uspešne organizacije, Univerza na Primorskem, Fakulteta za management Koper, 2009, izbrana poglavja.


Ettlie, J. E., Managing Innovation, Butterworth-Heinemann, 2006.

Ettlie, J. E., Managing Technological Innovation, John Wiley & Sons, 2000.

Rainey, D. L., Sustainable Business Development Inventing the Future Through Strategy, Innovation, and Leadership, Cambridge University Press, 2010.

Cooper, R.G., Winning at New Products: Creating Value Through Innovation, Basic Books, 2011.



Spoznati vsebino in pomen:

managementa inoviranja in inovacij

inoviranja in strateškega planiranja v podjetju

inoviranja in sistema kakovosti v podjetju

vloge RiR v podjetju

principov vodenja in upravljanja RiR

izhodišč, pomena in umestitve RNP

izvedbenega procesa RNP

To acquaint the content and meaning:

innovation management

innovations and strategic planning

innovations and quality management

R&D in business unit

management R&D

NPD processes

process of the implementation NPD



Znanje in razumevanje: - pomena in vsebine inoviranja, inovacijskih

procesov v podjetju in nacionalni ekonomiji - vodenja in upravljanja RiR - pomena managementa RNP


- razumevanje inovacijske verige in pomena managementa pri svojem delu

- zavedanje pomena RiR v podjetju - zavedanje pomena RNP

Knowledge and Understanding: - of the meaning of innovation, principles and

processes within the company and within national economy

- management of the R&D - the importance of NPD management

Transferable/Key Skills and other attributes: - to understand innovation chain and innovation

management - to understand meaning of RiR in the company - to understand meaning of the NPD proces



- predavanja - multimedijske predstavitve - obravnave primerov - obravnava aktualnega stanja inoviranja v

državi - delo na internetu - seminarske vaje - priprava elaborata

- lectures - multimedia presentations - case studies - discussion about the actual national innovation

system - online www search - seminar training - preparation of the expert's detail report



Assessment:


- predstavitev projekta

60

Student has to pass successfully the following obligations: - project presentation

59

- projektno delo - ustni izpit

20 20

- project work - oral examination


NAROBE, Miha, GOLOB, Janvit, KLINAR, Dušan, FRANCETIČ, Vojmir, LIKOZAR, Blaž. Co-gasification of biomass and plastics: pyrolysis kinetics studies, experiments on 100 kW dual fluidized bed pilot plant and development of thermodynamic equilibrium model and balances. Bioresource technology, ISSN 0960-8524. [Print ed.], Jun. 2014, vol. 162, str. 21-29. http://www.sciencedirect.com/science/article/pii/S096085241400426X, doi: 10.1016/j.biortech.2014.03.121. [COBISS.SI-ID 5457690]

LAH, Branko, KLINAR, Dušan, LIKOZAR, Blaž. Modeling, optimization and scale-up of waste tire pyrolysis. V: 6th Dubrovnik Conference on Sustainable Development of Energy, Water and Environment Systems, September 25 - October 29, 2011, Dubrovnik, Croatia. Conference proceedings. [S. l.: s. n.], 2011, str. [1-15], ilustr. [COBISS.SI-ID 4837146]

KLINAR, Dušan, BRENCELJ, Albin. Metoda za ciklično vakumiranje v šaržnem reaktorju : patent št. SI 23545 A, datum objave 31. 05. 2012; patentna prijava št. P-201000369 z dne 09. 11. 2010. Ljubljana: Urad RS za intelektualno lastnino, 2012. [5] str. [COBISS.SI-ID 16117782]

KLINAR, Dušan. Doseganje učinkovitosti rabe virov s kombiniranjem snovne in energetske izrabe = Resource efficiency by combination of material and energy recovery path. V: Strokovno posvetovanje 2014 Gospodarno in odgovorno!, Moravske Toplice, Hotel Ajda, 20. in 21. marec 2014. Ljubljana: Zveza ekoloških gibanj Slovenije, 2014, str. 115-121, ilustr. [COBISS.SI-ID 17909014]

HARB, Darja, SELINŠEK, Zdenka, KLINAR, Dušan, PETEK, Janez. Okoljska ekonomika in podjetništvo : sestavina študijskega programa. [Ljubljana: CPI, 2011]. http://www.cpi.si/files/cpi/userfiles/Datoteke/kurikulum/Programoteka/PROG-VIS/Bionika/Bionika_2011_P10_Bionska_ekonomika_in_podjetni%C5%A1tvo.doc [COBISS.SI-ID 356479]

http://www.sciencedirect.com/science/article/pii/S096085241400426X

http://dx.doi.org/10.1016/j.biortech.2014.03.121




http://www.cpi.si/files/cpi/userfiles/Datoteke/kurikulum/Programoteka/PROG-VIS/Bionika/Bionika_2011_P10_Bionska_ekonomika_in_podjetni%C5%A1tvo.doc

http://www.cpi.si/files/cpi/userfiles/Datoteke/kurikulum/Programoteka/PROG-VIS/Bionika/Bionika_2011_P10_Bionska_ekonomika_in_podjetni%C5%A1tvo.doc

60

Čistejša proizvodnja


Predmet: Čistejša proizvodnja

Course title: Cleaner Production




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6


Jeziki / Languages:




Prerequisites:

Načrtovanje procesov Razvoj produktov in procesov

Process Design Product and Process Development


Principi čistejše proizvodnje: - Hierarhija čistejše proizvodnje (preprečevanje

v fazi načrtovanja, zmanjševanje na viru, obtakanje, obdelava, uničevanje, odlaganje).

- Izbor surovin, katalizatorjev, topil, reakcijskih poti.

- Osnovne operacije in čistejša proizvodnja (kemijski reaktorji, separacija, obtakanje, obratovanje, pogonski sistemi).

Medprocesna integracija z uščipno metodo.

Modeliranje masnih prenosnikov in sinteza omrežij masnih prenosnikov za čiščenje odpadnih tokov.

Okoljski vplivi procesov in proizvodov z analizo življenjskega cikla.

Seminarske vaje: Reševanje primerov medprocesne toplotne integracije z uščipno metodo. Reševanje primerov

The principles of cleaner production: - Cleaner production hierarchy (prevention

during the design, source reduction, recycling, treatment and disposal).

- Selection of raw materials, catalysts, solvents, reaction pathways.

- Unit operations and cleaner production (chemical reactors, separation, recycling, process operation, utility systems)

Total Site Integration by Pinch method.

Modelling mass-exchange units, and synthesis of mass-exchange networks for treatment of waste streams.

Environmental impacts of processes and products by Life Cycle Analysis (LCA).

Seminar work: Case studies of total site integration by pinch method. Case studies of mass-exchange synthesis

61

sinteze masnih omrežij za okoljske aplikacije, ekonomske analize, optimizacija. Ocenjevanje okoljskih vplivov z metodo LCA. Individualno delo na primerih s področja čistejše proizvodnje in priprava pisnega poročila.

for environmental applications, economic analyses, optimization. Life Cycle Analysis of environmental impacts. Individual work on cleaner production case studies and preparation of written report.


El-Halwagi M. M. Sustainable Design Through Process Integration. Elsevier, Oxford, 2012.

Klemeš J., Friedler F., Bulatov I., Varbanov P., Sustainability in the Process Industry, Integration and Optimization, McGraw Hill, 2011.



Mulholland K. L. Identification of Cleaner Production Improvement Opportunities. John Wiley & Sons, New Jersey, 2006.

Azapagić A. Perdan S., Clift R. Sustainable development in practice. John Wiley & Sons, Chichester, 2004.

Allen D. T., Ahonnard D. R. Green Engineering – Environmentally Conscious Design of Chemical Processes. Prentice Hall, Upper Saddle River, 2002.



Razumevanje kompleksnejših metodologij in metod čistejše proizvodnje v procesih, storitvah, razumevanje nastajanja vplivov na okolje v vseh fazah življenjskega kroga, razviti celovit pogled na okoljski vpliv proizvoda v vseh fazah življenjskega kroga proizvoda in načini znižanja teh vplivov na obstoječih ali proizvodih v načrtovalni fazi.

Understanding complex cleaner production methodologies and techniques of the production processes and services. Understanding environmental impacts of the entire life cycle of products, knowing possibilities of the decreasing the environmental impacts of existing and new products during the design phase.


Študent bo sposoben: - Analizirati možnosti za toplotno integracijo med

procesi z uščipno metodo. - Analizirati možnosti za masno integracijo med

tokovi v procesu in predlagati omrežje masnih prenosnikov za odstranjevanje kontaminantov iz odpadnih tokov.

- Izvesti modeliranje in dimenzioniranje procesov za čistejšo proizvodnjo in oceniti ekonomiko alternativnih tehnologij.

- Oceniti okoljske vplive procesov in proizvodov v življenjskem ciklu.

- Primerjati alternativne tehnologije in izbrati najustreznejšo z upoštevanjem okoljskih in ekonomskih vidikov.

Prenesljive/ključne spretnosti in drugi atributi: Celostni pristop k okoljski analizi procesov. Uporaba tehnik in metodologij ČP, LCA in okoljskega načrtovanja.

Student will be able to: - Analyze targets for heat integration among several

processes (Total Site Integration) by Pinch method.

- Analyze mass integration targets for process streams, and propose mass-exchange networks for removal of contaminants from waste streams.

- Make modelling and sizing of cleaner production processes, and evaluate the economics of alternative technologies.

- Evaluate environmental impacts of processes and products through Life Cycle Analysis.

- Compare alternative technologies and choose the appropriate one by taking into account environmental and economic factors.

Transferable/Key Skills and other attributes: Integral approach to the process analysis. Application of the methodologies and techniques of CP, LCA and Eco-design.

62


Predavanja z diskusijo, izdelava posamičnega ali skupinskega seminarskega dela z uporabo ustrezne programske opreme.

Lecture with discussion of the practical problems, carrying out the individual or team seminar work.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - ustni izpit - seminarska naloga - predstavitev seminarske naloge

30 50 20

Student has to pass successfully the following obligations: - oral examination - seminar work - presentation of seminar work


TOKOS, Hella, NOVAK-PINTARIČ, Zorka, YANG, Yongrong. Bi-objective optimization of a water network via benchmarking. Journal of cleaner production, ISSN 0959-6526. [Print ed.], 2013, vol. 39, str. 168-179, doi: 10.1016/j.jclepro.2012.07.051. [COBISS.SI-ID 16240918]

KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka, SIMONIČ, Marjana, ŠKOF, Gorazd. Optimizacija obstoječe in načrtovanje nove naprave za čiščenja odpadnih oljnih emulzij : zaključno poročilo projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, Laboratorij za procesno sistemsko tehniko in trajnostni razvoj, 2013. 53 str., ilustr. [COBISS.SI-ID 17120534]

TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and benchmarking of breweries. Clean technologies and environmental policy, ISSN 1618-954X, 2012, vol. 14, no. 2, str. 173-193, doi: 10.1007/s10098-011-0390-0. [COBISS.SI-ID 15021334]

KRAVANJA, Zdravko, ROPOTAR, Marcel, NOVAK-PINTARIČ, Zorka. Two-step multiobjective synthesis of sustainable chemical processes. Theoretical foundations of chemical engineering, ISSN 0040-5795, 2012, vol. 46, no. 6, str. 689-698. [COBISS.SI-ID 16434710]

TOKOS, Hella, NOVAK-PINTARIČ, Zorka. Development of a MINLP model for the optimization of a large industrial water system. Optimization and engineering, ISSN 1389-4420, 2012, vol. 13, iss. 4, str. 625-662, doi: 10.1007/s11081-011-9162-2. [COBISS.SI-ID 15125014]

63

Mehanika fluidov II


Predmet: Mehanika fluidov II

Course title: Fluid Mechanics II




Semester Semester



2. zimski

Autumn



Predavanja Lectures

Seminar Seminar

Sem. vaje Tutorial


work



ECTS

15 15 150 6


Jeziki / Languages:




Prerequisits:

Osnovno znanje matematike. Basic knowledge of mathematics.


Ne–Newtonove tekočine: razvrstitev, napetosti in viskoznost v ceveh

Pretok skozi nanešene plasti: karakteristike plasti, izgube trenja, mehanska energijska bilanca

Pretok v fluidiziranih plasteh

Padajoči delci v fluidu

Dvofazni tok

Vodni in plinski pretočni sistemi: faktor istočastnosti, načrtovanje in dimenzioniranje, optimizacija, namestitev črpalk, tranzientni pojavi, izbira pretočnih poti.

Seminarske vaje: Vaje se navezujejo na tematiko predmeta

Študent samostojno reši deset praktičnih primerov

Non – Newton fluids: classification of fluids, shear stress and viscosity, flow in pipes

Flow through packed beds: characterization of a packed bed, frictional loss, and mechanical energy balance.

Flow in fluidized beds: the fluidized state, frictional loss and pumping requirement to fluidize a bed of solids, minimum fluidizing velocity

Solid particles falling through fluids

Two phase flow

Water and gas flow systems: factor of simultaneity, design and dimensioning, optimisation, location of pumps, transient phenomena

Tutorials will be based on chosen topic regarding the theme of the subject.

64

Students individually solve ten practical examples.


Frank M. White, Fluid Mechanics 6th edition, McGraw Hill, 2008.


James O. Wilkes: Fluid Mechanics for Chemical Engineers with Microfluids and CFD 2nd Edition, Prentice Hall, 2005.

Octave Levenspiel, Tracer Technology: Modeling the Flow of Fluids, Springer; 2012.

Pijush K. Kundu, Ira M. Cohen: Fluid Mechanics, Second Edition, Academic Press, 2001.

Joel H. Ferziger, Milovan Peric: Computational Methods for Fluid Dynamics, Springer Verlag, 2001.



Osnovne informacije o vrstah, pomenu in lastnostih vodnih in plinskih omrežij Osvojiti postopke modeliranja sistemov

Basic information about the types, meaning and the characteristics of water and gas networks



Znanje in razumevanje: • Slušatelji se seznanijo z nekaterimi temeljnimi in

praktičnimi znanji vezanimi na energetska omrežja.

Prenesljive/ključne spretnosti in drugi atributi: • Prenos teorije na reševanje praktičnih primerov

Knowledge and Understanding: • Of fundamental and practical knowledge

regarding energy networks Transferable/Key Skills and other attributes: • Using the theory to solve practical problems



Predavanja: študent spozna teoretične vsebine predmeta. Seminarske vaje: študent utrdi teoretično znanje in spozna aplikativne možnosti reševanja primerov iz prakse, študent izdela krajšo študijo oziroma projekt, ki se navezuje na tematiko predmeta.

Lectures: the student gets acquainted with theoretical content of the subject. Seminar: the student upgrades the theoretical knowledge with practical experience, conducting a short study or project regarding the thematic of the subject.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: • seminarska naloga • računski del izpita • teoretični del izpita Teoretični in računski del tvorita celoto in se preverjata hkrati.

30 40 30

Student has to pass successfully the following obligations: • individual paper • calculation part of the exam • theoretical part of the exam The theoretical and the calculus part of exam are performed simultaneously.

http://www.amazon.com/Octave-Levenspiel/e/B001H6IOJU/ref=dp_byline_cont_book_1

65


JOTANOVIĆ, Milovan, MIŠČEVIĆ, Mirko, KULČAR, Bojan, GORIČANEC, Darko. Optimal proportion of refrigerants in single- stage high-temperature heat pump. International journal of systems applications, engineering & development, ISSN 2074-1308. [Online ed.], 2012, vol. 6, iss. 6, str. 365-375. http://www.naun.org/multimedia/UPress/saed/16-565.pdf. [COBISS.SI-ID 16535830]

KROPE, Jurij, GORIČANEC, Darko, DOBERŠEK, Danijela. Optimizacija lokacije deponije, tehnologije transporta in doziranja komunalne biomase v sušilnik premoga TET : končno poročilo. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2012. 90 f., ilustr. [COBISS.SI-ID 16563222

DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Dryers for sewage sludge dehydration. International journal of energy and environment, 2012, vol. 6, iss. 6, str. 588-596. http://www.naun.org/multimedia/NAUN/energyenvironment/16-691.pdf. [COBISS.SI-ID 16535062]

ZORKO, Jerneja, GORIČANEC, Darko, KROPE, Jurij. Process of oxygen transfer and power requirements in activated sludge wastewater treatment plant. Research Journal of Chemistry and Environment, ISSN 0972-0626, 2011, vol. 15, no. 2, str. 1-3, graf. prikazi. [COBISS.SI-ID 15168534],

DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Use of drag-reducing additives in district heating systems. V: The fifth International Conference on Thermal Engineering: Theory and Applications [also] ICTEA, May 10-14, 2010, Marrakesh, Morocco. Proceeding. [S. l.]: ICTEA, cop. 2010, str. 231-234. [COBISS.SI-ID 14194454]

http://www.naun.org/multimedia/UPress/saed/16-565.pdf



http://www.naun.org/multimedia/NAUN/energyenvironment/16-691.pdf




66

Termodinamika zmesi


Predmet: Termodinamika zmesi

Course title: Solution Thermodynamics




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6


Jeziki / Languages:




Prerequisites:

Osnovno znanje termodinamike

Basic knowledge of thermodynamics

Vsebina:


Predavanja

Termodinamika faznih ravnotežij: osnovne enačbe in parcialni odvodi, lastnosti čistih snovi in realnih zmesi in metode določanja, enačbe stanja, fugativnost in fugativnostni koeficient, aktivnost in aktivnostni koeficient.

Termodinamski opis zmesi: Parcialne molarne količine, presežne količine, fugativnost, aktivnost in aktivnostni koeficient.

Večfazni sistemi: ravnotežje in stabilnost, fazni prehodi.

Fazni diagrami ter termodinamski in empirični modeli za opis ravnotežij v sistemih plin-tekoče, tekoče-tekoče, trdno-tekoče in sistemih pri visokih tlakih.

Računalniške vaje: Izračun faznih ravnotežij z uporabo programskih orodij (npr. Aspen Plus,…):

Lectures

Classical thermodynamics of phase equilibria: basic equations and partial derivatives, properties of pure substances and real mixtures and methods

for determination, equations of state, fugacity and activity.

The thermodynamic description of mixtures: partial molar properties, excess properties, fugacity, activity and activity coefficient.

Multiphase systems: Equilibrium and stability, phase transitions.

Phase diagrams, thermodynamic and empirical models for description of equilibria in systems Gas-liquid, Liquid-liquid, Solid-liquid, and systems at high pressure.

Computational work:

Calculation of phase equilibria using software (e.g Aspen Plus,…):

67

- Izračun ravnotežij v sistemih plin-tekoče, - Topnost plinov v tekočinah, - Topnost trdnih snovi v tekočinah, - Ravnotežja v sistemih pri visokih tlakih.

- Calculation of gas-liquid equilibria, - Solubility of gasses in liquids, - Solubility of solids in liquids, - High pressure equilibria,


J. V. Sengers, R. F. Kayser, C. J. Peters and H. J. White, Jr., Equations of State for Fluids and Fluid Mixtures, Elsevier Science B. V., 2000.

J. M.Prausnitz, R. N.Lichtenthaler, E. G. de Azevedo, Molecular thermodynamics of Fluid-Phase Equilibria, 3rd ed., Prentice Hall, New Jersey, 1998.


Stanley T. Sander, Chemical, Biochemical, and Engineering Thermodynymics, John Wiley&Sons, 2006. High-Pressure Fluid Phase Equilibria, Volume 2: Phenomenology and Computation (Supercritical Fluid

Science and Technology), Eds.: U. K Deiters, Thomas Kraska, Elsevier; 1 edition, 2012.



Uporaba termodinamike v mešanicah, s poudarkom na neidealnih mešanicah. Splošne metode, enačbe stanja in drugi termodinamski modeli, potrebni za kvantitativno obravnavanje mešanic in večkomponentnih zmesi.

Application of thermodynamics to mixtures (solutions), with emphasis on non-ideal mixtures. Generalized methods, equations of state and other thermodynamic models, needed for quantitative treatment of mixtures and multicomponent mixtures.


Znanje in razumevanje: Po zaključku tega predmeta bo študent sposoben

razumeti zakone termodinamike na višjem nivoju, predvsem za mešanice, večsnovne sisteme in večkomponentne raztopine;

uporabiti enačbe stanja za večsnovne sisteme;

obvladati termodinamske izračune za takšne sisteme.

Knowledge and Understanding: On completion of this course the student will be able to

understand laws of thermodynamics on a higher level, above all for mixtures, multicomponent mixtures and solutions;

use equations of state for multicomponent systems;

govern in a great extend thermodynamic calculations for such systems

Prenesljive/ključne spretnosti in drugi atributi: Spretnost komuniciranja, predvsem sposobnost zbiranja potrebnih informacij za termodinamske izračune v zmeseh. Reševanje bolj zapletenih termodinamskih problemov.

Transferable/Key Skills and other attributes: Communication skills, preferable the capability of collecting needed information's for thermodynamic calculations in mixtures. Solution of more sophisticated thermodynamic problems.


predavanja

računalniške vaje

Lectures

Computer work



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: Ocenjevanje predmeta

Projektno delo (računalniške vaje)

Ustni izpit

50 50

Student has to pass successfully the following obligations: Assessment of the subject

Project (computational work)

Defense of the project and oral exam

68


ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str. 129-136, [COBISS.SI-ID 18135574].

PERKO, Tina, KNEZ, Željko, ŠKERGET, Mojca. Phase equilibria of glycerol tristearate and glycerol trioleate in carbon dioxide and sulfur hexafluoride. Journal of chemical and engineering data, ISSN 0021-9568, 2012, vol. 57, no. 12, str. 3604-3610, [COBISS.SI-ID 16419350].

ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter. Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311 [COBISS.SI-ID 13799446].

ŠKERGET, Mojca. Phase equilibrium in supercritical fluids : invited lecture presented at the International scientific colloquium Center of applied spectroscopy, 29 - 30 September, 2011, UM FKKT, Maribor. 2011. [COBISS.SI-ID 15456534].

KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010, str. [3]-38. [COBISS.SI-ID 14789910].

PERKO, Tina, GUMZEJ, Jerneja, KNEZ, Željko, ŠKERGET, Mojca. Phase equilibria of flax seed oil - dense gases. V: 2nd Conference on Applied Biocatalysis and 7th Meeting of Students and University Professors from Maribor and Zagreb, November 7th and 8th 2011, Maribor, Slovenia. LEITGEB, Maja (ur.), PRIMOŽIČ, Mateja (ur.). 2nd Conference on "Applied Biocatalysis" and 7th Meeting of Students and University Professors from Maribor and Zagreb, November 7th and 8th 2011, Maribor, Slovenia. Maribor: Faculty of Chemistry and Chemical Engineering; Zagreb: Faculty of Chemical Engineering and Technology, 2011, 4 str. [COBISS.SI-ID 15534358].

69

Upravljanje z okoljem


Predmet: Upravljanje z okoljem

Course title: Environmental Management




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Damjan Krajnc

Jeziki / Languages:




Prerequisites:

Ni pogojev. None.


Predavanja: Okoljski vplivi tehnoloških sistemov Evropska zakonodaja in mednarodni standardi Koncept in razvoj upravljanja z okoljem Metode okoljskega in ekološkega pregleda Teorija in praksa upravljanja z okoljem Sistemi ravnanja z okoljem Družbena odgovornost Merjenje trajnostnega razvoja Vseživljenjsko vrednotenje stroškov, okoljska presoja Večkriterijsko odločanje Seminarske vaje: Osnovane na izbrani temi: okoljska zakonodaja in predpisi, vzpostavitev sistemov upravljanja z okoljem v izbranih podjetjih iz različnih sektorjev, pregled poročil o trajnostnem razvoju podjetij, primeri večkriterijskega odločanja pri upravljanju z okoljem, okoljskih vplivi proizvodnih procesov,

Lectures: Environmental impacts of technological systems Environmental law, regulations and organizations Concept and Development of Environmental Management Methods of Environmental and Ecological Auditing Theory and Practice of environmental management Environmental Management Systems Corporate Social Responsibility Measuring Sustainable Development Life cycle costing, environmental impact assessment Multi-criteria decision making Seminar work: Will be based on chosen topic: environmental laws and regulations, implementation of environmental management systems in chosen companies from different industrial sectors, review of sustainability reports of companies, examples of multi-criteria decision making, environmental impact of production processes, role of selected fields of technological

70

vloga in vpliv izbranih področij tehnološkega razvoja na globalni trajnostni razvoj.

development in global sustainable development.


Krajnc D. Upravljanje z okoljem (zbrano gradivo), 2009, Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, http://www.fkkt.um.si/egradiva/fajli/upravljanje_z_okoljem.pdf.


Weiß P., Bentlage J., Environmental Management Systems and Certification, The Baltic University Press, 2006.

Mulder K. Sustainable Development for Engineers – A Handbook and Resource Guide. Greenleaf Publishing Ltd, Sheffield UK, 2006.



Razumevanje okoljskih vidikov in predpisov, razvoja okoljskih strategij, poročanja o okoljskem in trajnostnem delovanju, sistemov upravljanja z okoljem, okoljskega računovodstva in pregledov, večkriterijskega odločanja pri upravljanju z okoljem

Understanding of environmental issues and regulations, development of environmental strategies, environmental and sustainability performance reporting, environmental management systems, environmental accounting and auditing, multi-criteria decision making.


Znanje in razumevanje: Po opravljenem predmetu bo študent sposoben prepoznati in razumeti pomembnost upravljanja z okoljem za stanje podjetja glede okoljskih izzivov in konkurenčnosti. Študent bo sposoben uporabljati metode okoljskih pregledov v podjetju in bo seznanjen s teorijo in postopki vpeljevanja sistemov upravljanja z okoljem v podjetju. Sposoben bo razviti okoljske strategije, uporabljati okoljske in trajnostne kazalce, izvajati okoljsko merjenje in preglede ter vključevati večkriterijsko odločanje v sistem upravljanja z okoljem. Pridobil bo znanje o konceptih, teorijah, metodah in orodjih pri industrijskem upravljanju z okoljem. Prenesljive/ključne spretnosti in drugi atributi: Po opravljenem predmetu bo študent pridobil naslednje spretnosti:

predlagati pristope k uvajanju upravljanja z okoljem v podjetju,

uporabljati metode okoljskega in ekološkega pregleda,

načrtovati in voditi projekte, uporabljati metode večkriterijskega odločanja,

uporabljati informacijske tehnologije.

nowledge and Understanding: Completing the course the student will be able to recognize and understand the importance of environmental management for the situation of the company regarding environmental challenges and competitiveness. The student should be able to use methods of environmental and ecological auditing and be acquired with the theory and implementation procedure for environmental management systems in companies. The student will be able to use environmental and sustainability performance indicators, environmental accounting and auditing and implement multi-criteria decision making in the environmental management. The student will acquire the knowledge of the concepts, theories, methods and tools of industrial environmental management. Transferable/Key Skills and other attributes: On the completion of the course the student will acquire the following skills:

propose approaches for environmental management implementation in company,

use methods of environmental and ecological auditing,

plan and manage projects, use methods of multi-criteria decision making,

use information technologies.

71


Predavanja, vaje, samostojni študij problema, izdelava posamične ali skupinske seminarske naloge.

Lectures, exercises, independent problem study, carrying out the individual or team seminar work.



Assessment:


pisni izpit

seminarska naloga

predstavitev seminarske naloge

50 40 10


written examination

seminar work

seminar work presentation


TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and benchmarking of breweries. Clean technologies and environmental policy, 2012, vol. 14, no. 2, str. 173-193.

CZEKAJ, Marta, KRAJNC, Damjan. Sustainability assessment regarding the regional development of Sucha Beskidzka County, Poland. Polish journal of environmental studies, ISSN 1230-1485, 2011, vol. 20, no. 4A, str. 50-56.

KOLETNIK, Damijan, LUKMAN, Rebeka, KRAJNC, Damjan. Environmental management of waste based on road construction materials. Aplinkos tyrimai, inžinerija ir vadyba, ISSN 1392-1649, 2012, vol. 59, no. 1, str. 42-46.

72

Eko-dizajn in ocena življenjskega cikla


Predmet: Eko-dizajn in ocena življenjskega cikla

Course title: Eco-design and life cycle assessment




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Damjan Krajnc

Jeziki / Languages:




Prerequisites:

Ni pogojev None


Uvod v industrijsko ekološko načrtovanje: definicija in vloga v kemijski in procesnih industrijah,

Snovni tokovi in eko-načrtovanje (vplivi na okolje in dileme, razpoložljivost in izčrpanost surovinskih virov),

Strategije in koncepti eko-načrtovanja razvoj novega koncepta, raba materialov in vsebnost kemikalij, zmanjšanje snovnih tokov in porabe energije, načrtovanje za proizvodnjo, distribucijo, uporabo, odstranitev, podaljševanje življenjske dobe),

Določitev ciljev in področja (ozadje analize, zahteve glede modeliranja, načrtovanje študije LCA),

Inventarizacija (priprava diagrama poteka, zbiranje podatkov, postopek izračuna, alokacija),

Analiza življenjskega cikla (okoljski vplivi, različne faze LCIA, metode karakterizacije)

- Introduction to Industrial Eco-Design: definition and role in chemical and process industries,

- Resources flow and eco-design (environmental impact and dilemma of resource flows, resource availability and depletion),

- Strategies and concepts of eco-design new concept development, materials application and chemical content, reducing material flows, reduction of energy consumption, design for production, distribution, use, end-of-life, product lifetime extension),

- Goal and scope definition (context of the study, modelling requirements, planning of an LCA study),

- Inventory analysis (construction of a flowchart, data collection, calculation procedure, allocation),

- Life cycle impact assessment (what is an environmental impact, different phases of life cycle impact assessment, characterisation

73

Razlaga in prikaz rezultatov (kvantitativni rezultati, testiranje robustnosti rezultatov),

Kritični pregled LCA,

Upravljanje podatkov LCA (programski paketi, baze podatkov, dokumentiranje LCA),

Zeleno oglaševanje, nabavljanje in okoljsko označevanje,

Okoljska politika do proizvodov. Seminarske vaje: študent bo z metodologijo, orodji in programsko opremo obdelal določen problem iz področja eko-dizajna in metode ocenjevanja življenjskega cikla.

methods), - Interpretation and presentation of results

(quantitative results, testing the robustness of the results),

- Critical review of LCA, - LCA data management (software packages,

databases, documentation of LCA) - Green marketing, procurement and eco-

labelling; - Product-oriented environmental policies.

Seminar work: Student will independently solve problem in the field of eco-design and life cycle assessment using methodology, tools and software.


Krajnc D. 2014. Eko-dizajn - Okoljsko načrtovanje, razvoj in analiziranje proizvodov in procesov. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo.


Zbiciński I., Stavenuiter J., Kozlowska B., van de Coevering H.P.M. 2006. Product Design and Life Cycle Assessment. The Baltic University Press.

Bauman H., Tillman A.M. 2004. The Hitch Hiker's Guide to LCA. Studentlitteratur AB. European Commission - Joint Research Centre - Institute for Environment and Sustainability:

International Reference Life Cycle Data System (ILCD) Handbook - General guide for Life Cycle Assessment - Detailed guidance. First edition March 2010. EUR 24708 EN. Luxembourg. Publications Office of the European Union; 2010.

74


Razumevanje metodologije okoljskega načrtovanja, poznavanje metod ocenjevanja vplivov na okolje v celotnem življenjskem ciklu proizvoda, metod načrtovanja posameznih faz življenjskega cikla, poznavanje in uporaba ustrezne programske opreme za okoljsko načrtovanje proizvodov.

Understanding the eco (re)design methodologies and tools, understanding environmental impact assessment methods, be able to design life cycle phases of products, and use the eco design and LCA software.


Znanje in razumevanje: Študent mora biti sposoben izvesti analizo življenjskega cikla proizvoda, z obstoječimi orodji in programsko opremo ovrednotiti vplive na okolje v vseh fazah življenjskega cikla, obvladati tehnike izboljšanja obstoječih in načrtovanja novih proizvodov ter procesov, ki bodo imeli ekonomsko in okoljsko sprejemljive vplive na okolje in stroške. Prenesljive/ključne spretnosti in drugi atributi: Celostni pristop k načrtovanju proizvodov in/ali storitev. Poznavanje metodologij okoljskega načrtovanja proizvodov in storitev. Uporaba osnovnih metod okoljskega izboljšanja obstoječih in načrtovanja novih procesov.

Knowledge and Understanding: Student should be able to perform the LCA of a product, with the help of existing tools and software to carry out environmental impact assessment of all product life cycle phases, be able to develop new concepts of products (existing and/or new ones) and processes with environmentally and economically acceptable impacts on the environment and costs Transferable/Key Skills and other attributes: Integral approach to the eco (re)design of products and services. Knowledge of the methodologies to be used in eco (re)design. Application of the basic methods and environmental improvements of the existing and new processes.



Predavanja, vaje, samostojni študij problema, izdelava posamične ali skupinske seminarske naloge.

Lectures, exercises, independent problem study, carrying out the individual or team seminar work.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - pisni - seminarska naloga - predstavitev seminarske naloge

50 40 10

Student has to pass successfully the following obligations: - written examination - seminar work - seminar work presentation


KRAJNC, Damjan. Okoljski vplivi različnih nagrobnih sveč in metoda LCA. Embalaža, okolje, logistika, ISSN 1855-4849, nov. 2010, št. 54.

KRAJNC, Damjan. Vzpostavljanje ekoindustrijskih sistemov z načeli industrijske simbioze = The establishment of eco-industrial systems including the principles of industrial symbiosis. V: VOLFAND, Jože (ur.), ČERNUTA, Uroš. Odpadki v Sloveniji = Waste in Slovenia, (Zbirka Zelena Slovenija). Celje: Fit media, 2010.

RADONJIČ, Gregor, PISNIK, Aleksandra, KRAJNC, Damjan. Product ecodesign in companies with ISO 14001 certified environmental management system. Environmental engineering and management journal, ISSN 1582-9596. Jan. 2015, vol. 14, no. 1, str. 176-181.

TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and benchmarking of breweries. Clean technologies and environmental policy, 2012, vol. 14, no. 2, str. 173-193.

ZHOU, Li, TOKOS, Hella, KRAJNC, Damjan, YANG, Yongrong. Sustainability performance evaluation in industry by composite sustainability index. Clean technologies and environmental policy, Oct. 2012, vol. 14, iss. 5, str. 789-803.

75

Surovine in proizvodnja premazov


Predmet: Surovine in proizvodnja premazov

Course title: Raw Materials and Manufacture of Coatings




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6


Jeziki / Languages:




Prerequisites:

Osnovno znanje organske kemije z dodiplomskega študija.

Basic knowledge of organic chemistry from undergraduate study.

Vsebina:


kaj so premazi: definicije, sestava.

veziva: naravna, modificirana naravna, sintetična.

topila: klasifikacija in definicije, karakterizacija topil, lastnosti, topila v premaznih materialih.

pigmenti in polnila: definicije in klasifikacija, fizikalne, beli pigmenti, črni pigmenti, anorganski barvni pigmenti, organski barvni pigmenti, sijajni pigmenti, funkcionalni pigmenti, polnila, barve.

aditivi: definicije in klasifikacija, površinsko aktivni aditivi, reološki aditivi, stabilizatorji svetlobe, biocidi, močljivci in dispergirna sredstva, katalizatorji in sušilna sredstva.

zakonodaja.

barve in premazni sistemi, formulacija, tvorba filma (sušenje, zamreženje):

sestava barv, osnovni parametri formuliranja, lastnosti filma.

What are coatings: definitions, composition.

Film formers: Natural, Modified natural, Synthetic.

Solvents: Classification and definitions, Characterisation of solvents, Properties, Solvents in coating materials.

Pigments and fillers: Definitions and classification, pigment physic, White pigments, Black pigments, Inorganic coloured pigments, Organic coloured pigments, Lustre pigments, Functional pigments, Fillers, Dyes.

Additives: Definitions and classification, Interface-active additives, Rheological additives, Light stabilizers, Biocides, Wetting and dispersing agents, Catalysts and driers, Flatting agents.

Legislative Framework.

Paint systems, formulation, film-forming (drying and curing, crosslinking):

76

barve na osnovi topil, barve na vodni osnovi, radikalsko zamrežljivi premazni materiali, praškasti premazi, anorganski premazni materiali.

tvorba filma, sušenje in zamreženje.

proizvodnja barv in premazov:

procesne stopnje v proizvodnji premazov, naprave, formuliranje obdelovalne osnove, mešanje in raztapljanje, dispergiranje, drobljenje in gnetenje, filtracija, dispergiranje efektnih pigmentov, šaržni testi

Specifične lastosti proizvodnje vodnih lakov.

Proizvodnja praškastih premazov. Vaje: primeri premaznih sistemov, študij njihovih fizikalno kemijskih lastnosti ter vpliva na lastnosti premaza in možne napake, formulacije, sušenja in zamreženja premazov.

Composition of paints, Basic formulating parameters film properties.

Solvent-based paints, Waterborne paints, Radically-curing coating materials, Coating powders, Inorganic coating materials.

Film-forming, drying, curing (crosslinking).

Manufacture of paints and coatings:

Process stages in the manufacture of coatings, Configuration of equipment, Formulating the mill base, Mixing and dissolving, Dispersion, Grinding and kneading, Filtration, Dispersing effect pigments, Batch tests.

Special features of the production of waterborne enamels.

Manufacture of coating powders. Tutorial: Case study of coating types, their physical and chemical properties and influence on coating properties and common failure modes, formulation and film-forming (drying and curing, crosslinking).


Goldschmidt, H. J. Streitberger: BASF-Handbuch Lackiertechnik, Vincentz, Hannover, 2002.

B. Müller, U. Poth: Coatings formulation, Hannover: Vincentz, 2006.


K. Hunger (Ed.): Industrial Dyes, Chemistry, Properties, Applcations, Wiley-VCH, Weinheim, 2003.

H. Kittel, J. Spille (Hrsg.): Lehrbuch der Lacke und Beschichtungen, Bd. 5.; Hirzel, Stuttgart, 2003.

T. Brock, M. Groteklaes, P. Mischke: European Coatings Handbook, Curt R. Vincentz Verlag, Hannover 2000.



Cilj tega predmeta je osvojiti znanja o vrstah premaznih sistemov in njihovih surovinah ter o formuliranju, lastnostih ter procesnih stopnjah.

The objective of this course is to achieve knowledge of the coating systems, raw materials for coatings, formulation, properties, and process stages.



Poznavanje surovin za premaze in njihove lastnosti ter vpliv na lostnosti premaza;

Poznavanje zakonodaje;

Osnovne sestave in formuliranja premaznih sistemov, tipov premaznih materialov in njihovih lastnosti, tehnologij sušenja in zamreženja, mešanje in dispergiranje v proizvodnji barv.


Knowledge of raw materials for coatings, properties of specific compounds and the influence on the coating properties;

Legislation;

Basics of composition and formulations of paints, types of coating materials and their properties, technology of drying and curing, mixing and grinding (dispersing).


osnovna predznanja za delo v industriji barv in lakov


Achieving basic knowledge for the work in the industry of paints and coatings

77


Predavanja, seminarske vaje, strokovna ekskurzija v industrijo. Seminarska naloga: študent izdela krajšo študijo oz. projekt, ki se navezuje na tematiko predmeta.

Lectures, tutorial, visit to the industry. Individual project work: conducting a short study (project) regarding the thematic of the subject.



Assessment:


pisni izpit

seminarska naloga 60 40


written examination

Seminar work report


ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str. 129-136, doi: 10.1016/j.supflu.2014.08.019. [COBISS.SI-ID 18135574]

ČUČEK, Denis, PERKO, Tina, ILIĆ, Ljiljana, ZNOJ, Bogdan, VENTURINI, Peter, KNEZ, Željko, ŠKERGET, Mojca. Phase equlibiria[!] and diffusivity of dense gases in various polyethylenes. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], June 2013, vol. 78, str. 54-62, doi: 10.1016/j.supflu.2013.03.020. [COBISS.SI-ID 16830998],

ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter. Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311, doi: 10.1016/j.supflu.2009.10.013. [COBISS.SI-ID 13799446]

KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental applications. Amsterdam: Elsevier, 2014, str. 31-67, doi: 10.1016/B978-0-444-62696-7.00002-2. [COBISS.SI-ID 17592854]

ŠKERGET, Mojca. Formuliranje prašnih lakov z visokotlačnim postopkom : zaključno poročilo o rezultatih raziskovalnega projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2011. loč. pag. [COBISS.SI-ID 14953238]


78

Aplikacija, lastnosti in testiranje premazov


Predmet: Aplikacija, lastnosti in testiranje premazov

Course title: Application, Properties and Testing of Coatings




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 7,5 7,5 150 6


Jeziki / Languages:




Prerequisites:

Osnovno znanje organske in analizne kemije z dodiplomskega študija.

Basic knowledge of organic and analytical chemistry from undergraduate study.

Vsebina:


substrati in predobdelava: kovinski substrati, substrati iz umetnih mas, substrati iz lesa, mineralni substrati.

aplikacija in sušenje: metode uporabe in pogoji, ročni nanos, nanos s polivanjem, nanos z valji, potopno in poplavno barvanje in sorodne tehnike, razpršilno barvanje (metode z in brez elektrostatičnega naboja), praškasti premazi, razpršilne komore, sušilne naprave.

primeri procesov barvanja (avtomobilska industrija, umetne mase, lesna industrija in ostali industrijski procesi).

okolju prijazne barve in premazi (premazi s povišano vsebnostjo trdne snovi, vodni

Substrates and pretreatment: Metal substrates, Plastic substrates, Wood substrates, Mineral substrates.

Application and drying: Methods of application and criteria for use, Manual application by brushing, rolling, trowelling, wiping, Curtain coating, Roller coating, Dipping, flow coating and related applications, Electrodeposition coating, Spray application (methods without and with electrostatic charging), Powder coating, Spray booths, Drying installations.

Examples of coatings processes (automotive, car refinishing, plastic coating, other industrial processes, wood coating).

79

premazi, suspenzije, praškasti premazi, z radiacijo zamrežljive barve in laki, ostali premazni sistemi).

reologija in reometrija: osnove reologije, meritve pretočnih lastosti, viskoelastičnost.

značilnosti tekočih in trdnih produktov.

analitske vrednosti za trdne produkte.

testiranje tekočih barv in premazov: optične lastnosti, emisija, tvorba filma, tečenje in zamreženje, obstojnost.

specifični testi za praškaste premaze.

lastnosti premazov po aplikaciji: merjenje debeline filma, optične lastnosti filma, barva in kolorimetrija, Mehanske lastnosti filma, svetlobna obstojnost in vodoodpornost.

obstojnost premazov in premaznih sistemov. Vaje:

uporaba standardnih analiznih metod za testiranje premaznih sistemov in premazov: testiranje mehanskih lastnosti, reoloških lastnosti, kemijske obstojnosti, obstojnosti na zunanje vplive.

ekskurzija v industrijo.

Environment Compatible Paints and Coatings (High Solids, Waterborne Paints, Slurry, Powder Coatings, Radiation Curable Paints and Coatings, Other Coating Systems).

Rheology and rheometry: Rheological principles, Measuring flow behaviour, Viscoelasticity.

Characteristics of solvents and liquid products:

Analytical values for solids.

Testing of liquid paints and coatings: Optical properties, Emissions, Film-forming, flow and crosslinking, Ring circuit stability.

Specific tests for coating powders.

Features of coatings after application: Film thickness measurement, Optical film properties, colour and colorimetry, Mechanical film properties, Light stability and weather resistance.

Durability of coatings and coating systems. Labor work:

Application of standard analytical methods for testing of coating systems and coatings: testing of mechanical properties, rhheological properties, chemical resistance, weathering resistance.

Visit to the industry.


P. A. Schweitzer, Paint and Coatings: Applications and Corrosion Resistance, Taylor & Francis Group Boca Raton, 2006.

D. G. Weldon, Failure Analysis of Paints and Coatings, John Wiley & Sons Inc., 2001.


R. Dietrich, Paint Analysis, Vincentz Network, Hannover, 2009.

T. Brock, M. Groteklaes, P. Mischke: European Coatings Handbook, Curt R. Vincentz Verlag, Hannover 2000. [ISBN: 3-87870-559-X].

Goldschmidt, A; Streitberger: H.-J., BASF-Handbuch Lackiertechnik, Vincentz: Hannover, 2002.


Osvojiti znanja o optimalnih tehnikah nanosa in sušenja za različne premazne sisteme ter znanja o lastnostih premaznih sistemov, možnih napakah in analiznih metodah.

Achieving knowledge about optimal application and drying techniques of different coating systems and properties of coating systems, possible failures and analytical methods.



Poznavanje različnih tehnik nanosa tekočih in praškastih premazov.

Sposobnost izbire najboljše tehnike nanosa za dan primer kot tudi najboljše tehnike sušenja oz zamreženja z vidika kvalitete, ekonomike in ekologije.

Poznavanje lastnosti premaznih sistemov.


Variety of applications of fluid and powderous coating materials;

Selecting best method for a given challenge as well as the best drying resp. curing way depending on quality, economical and ecological view points;

Of properties of coating systems;

80

Poznavanje merilnih tehnik in analiznih metod za testiranje premazov.

Of analytical methods and measuring technics for testing coatings.

Prenesljive/ključne spretnosti in drugi atributi: osnovna predznanja za delo v industriji barv in lakov oz. na področjih njihove uporabe.

Transferable/Key Skills and other attributes: Achieving basic knowledge for the work in the industry of paints and coatings and areas of their application.


predavanja

strokovna ekskurzija v industrijo

laboratorijske vaje

Lectures

Visit to the industry

Laboratory work



Assessment:


laboratorijske vaje

pisni izpit 30 70


Laboratory work

Written examination


ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str. 129-136, doi: 10.1016/j.supflu.2014.08.019. [COBISS.SI-ID 18135574]

ČUČEK, Denis, PERKO, Tina, ILIĆ, Ljiljana, ZNOJ, Bogdan, VENTURINI, Peter, KNEZ, Željko, ŠKERGET, Mojca. Phase equlibiria[!] and diffusivity of dense gases in various polyethylenes. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], June 2013, vol. 78, str. 54-62, doi: 10.1016/j.supflu.2013.03.020. [COBISS.SI-ID 16830998],

ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter. Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311, doi: 10.1016/j.supflu.2009.10.013. [COBISS.SI-ID 13799446]

KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental applications. Amsterdam: Elsevier, 2014, str. 31-67, doi: 10.1016/B978-0-444-62696-7.00002-2. [COBISS.SI-ID 17592854]

ŠKERGET, Mojca. Formuliranje prašnih lakov z visokotlačnim postopkom : zaključno poročilo o rezultatih raziskovalnega projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2011. loč. pag. [COBISS.SI-ID 14953238]

http://dx.doi.org/10.1016/j.supflu.2014.08.019






http://dx.doi.org/10.1016/B978-0-444-62696-7.00002-2



81

Teorija membranskih transportov


Predmet: Teorija membranskih transportov

Course title: Theory of Membrane Transport




Semester Semester


2. Zimski

Autumn

Vrsta predmeta / Course type: Izbirni / Optional


Predavanja Lectures

Seminar Seminar

Sem. vaje Tutorial


work



ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Irena Petrinić

Jeziki / Languages:

Predavanja / Lectures: slovenščina / Slovene

Vaje / Tutorial: slovenščina / Slovene


Prerequisits:

Splošno znanje fizike, kemije in matematike. General knowledge of chemistry, physics and mathematics

Vsebina:


Membranski proces je proces separacije, ki zajema širok spekter problemov, od delcev do molekul. Na voljo so različne membrane za izvedbo procesov. Četudi so membrane lahko iz različnih materialov(organskega ali anorganskega izvora) in različne strukture ( porozne ali nepozorne), je osnovni princip ločevanja enak. Ta predmet vključuje:

Zgodovinski pregled razvoja membran

Membrane in klasifikacija membranskih procesov

Pretok skozi porozne/neporozne membrane

Mehanizmi mašenja

Upad pretoka

Membranski procesi v okoljski tehnologiji: proizvodnja pitne vode, recikliranje odpadne vode, dodatno čiščenje vode

A membrane process is a separation process that covers a broad range of problems from particles to molecules and a wide variety of membranes are available to design a process. Although the membranes may vary in material (organic, inorganic) and structure (porous, nonporous) the basic principle of membrane separation is the same. This course covers:

An overview of the historical development of membranes

Membranes and classification of membrane processes

Transport through porous/nonporous membranes

Fouling mechanisms

Flux decline

Membrane processes in environmental

82

Seminarske vaje: Vaje se navezujejo na tematiko predmeta. Študent samostojno reši nekaj praktičnih primerov

technology: production of drinking water, recycling of wastewater, additional polishing

Tutorials will be based on chosen topic regarding the theme of the subject. Students individually solve several practical examples.


Mulder, Marcel, Basic Principles of Membrane Technology, Kluwer Academic Publishers, Dordrecht, Netherlands, 2003.

Baker, R.W., Membrane technology and applications, 2nd ed., John Wiley, 2012.


Judd, S. Jefferson, B. Membranes for Industrial Wastewater Recovery and re-use. New York: Elsevier Advanced Technology, 2003.

Noble, Richard D., Stern, S. Alexander (Eds), Membrane Separations Technology - Principles and Applications, Elsevier, 1995.

Primarna literatura (npr. članki) s tematiko glede na študentovo področje raziskovanja /Primary literature (e.g. papers) corresponding to the student’s research interest.



Cilj predmeta je, da študentje pridobijo:

Pregled osnov membranske filtracijske tehnologije, membrane, in oblike membranskih modulov, membranskih filtracijskih sistemov in uporabo membranskih filtracij na področju obdelave odpadne vode

Pridobili bodo znanje membranske tehnologije in membranskih procesov ter njihovih aplikacij

Študenti bodo razvili sposobnost oblikovanja in reševanja inženirskih problemov, ki vključuje oblikovanje membran in membranskih modulov

Zagotoviti razumevanje splošnih načel separacijskih procesov, da študent vidi možnosti na dejanskih primerih separacijskih procesov

This course aims to give students:

An overview of the fundamentals of membrane filtration technology, membranes and membrane modules configuration, membrane filtration system configurations and membrane applications in the field of wastewater treatment

They will get the knowledge of membrane technology, membrane processes and applications

To develop the student's ability to formulate and solve engineering problems involving design of membranes and membrane modules

To provide an understanding of the general principles of separation processes to allow students to make sensible options given a separation task




S pridobitvijo znanja teorije, mehanizma delovanja in tehnološkega razvoja bo študentom dalo orodje za uporabo te relativno nove tehnologije tekom svojih raziskovanj in tudi na njihovih prihodnjih delovnih mestih.

Študent bo pridobil izkušnje in znanje na osnovi individualnega raziskovalnega dela.


Sposobnost izbrati optimalni membranski proces in napovedati mehanizem mašenja membran gleda na specifičnost odpadne vode.

Knowledge and understanding:

By getting knowledge on the theory, mechanism and technology development, this will give the students new tools in using this relatively new technology in their research and also in their future jobs.

The student shall gain experience and knowledge with regard to individual, scientific work.


Ability to determine the optimal membrane process, and predict membrane fouling for specific wastewater treatment

83


Pristop temelji na samostojnem delu študenta ob sodelovanju učiteljev (priprava na seminarske naloge, predstavitev seminarskih nalog, konzultacije z učitelji, priprava na izpit in izpit).

The approach is based on the student's own work in cooperation with teachers (preparation for the seminar, seminar presentations, consultations with teachers, preparing for the exam and the exam).



Assessment:


seminarska naloga

pisni izpit

ustni izpit

30 40 30


individual paper

written examination

oral examination


KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN 1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249

BAUMAN, Maja, KOŠAK, Aljoša, LOBNIK, Aleksandra, PETRINIĆ, Irena, LUXBACHER, Thomas. Nanofiltration membranes modified with alkoxysilanes : surface characterization using zeta-potential. Colloids and surfaces. A, Physicochemical and Engineering Aspects, ISSN 0927-7757. [Print ed.], 5. Apr. 2013, vol. 422, str. 110-117

VERLIEFDE, A. R. D., CORNELISSEN, E. R., HEIJMAN, S. G. J., PETRINIĆ, Irena, LUXBACHER, Thomas, AMY, Gary L., BRUGEN, B. van der, DIJK, J. C. van. Influence of membrane fouling by (pretreated) surface water on rejection of pharmaceutically active compounds (PhACs) by nanofiltration membranes. Journal of membrane science, ISSN 0376-7388. [Print ed.], Mar. 2009, vol. 330, iss. 1/2, str. 90-103

84

Transportni pojavi v bioloških sistemih in tehnologija biomimetike


Predmet: Transportni pojavi v bioloških sistemih in tehnologija biomimetike

Course title: Transport phenomena in biological systems and biomimetic technology




Semester Semester


2. Zimski

Autumn



Predavanja Lectures

Seminar Seminar

Sem. vaje Tutorial


work



ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Claus Hélix-Nielsen

Jeziki / Languages:

Predavanja / Lectures: angleščina / English

Vaje / Tutorial: angleščina / English


Prerequisits:

Osnovno znanje splošne in anorganske kemije, matematike in fizike.

Basic knowledge of general and inorganic chemistry, mathematics and physics.

Vsebina:


Predmet zajema tri glavne teme z naslovi:

Biomolekule (sestava beljakovin in membrane) in njihovo delovanje

Celice: lastnosti in delovanje izbranih celic, celična mehanika

Transport fluidov in osmozni pojavi v nano območju, biomembrane in prenos snovi skozi membrano

Računalniške vaje: Izračuni transportov fluidov in osmoznih pojavov v nano območju bioloških sistemov. Projektna naloga.

The course includes three main thematic topics:

Biomolecules (protein and membrane components) and their function.

Cells: properties and function of selected cells, cellular mechanics.

Transport of fluidics and osmotics phenomenom in nanoscale size, biomembranes and membrane transport.

Computer Exercises: Calculation of fluid transport and osmotic phenomenon in nanoscale size of biological systems. Project assignment.

85


Claus Hélix-Nielsen, Biomimetic membranes for sensor and separation applications. Chapters 2, 3, 4, 7, and 9. Springer Verlag, 2012. http://link.springer.com/book/10.1007%2F978-94-007-2184-5.


Julian Lewis, Peter Walter, Alexander Johnson, Keith Roberts, Martin Raff & Bruce Alberts, Molecular Biology of the Cell. Chapters 3, 10 and 11. Garland Science, 2008.

Rodney Cotterill, Biophysics – an Introduction. Chapters 5, 6, 8, and 11. Wiley, 2002.



Predmet predstavi izbrane sodobne teme, ki povezujejo področja med biofiziko, mikro in nano-velikostjo fizike. V Laboratoriju za vodno biofiziko in membranske procese (LWB) bomo uvedli nove raziskovalne dejavnosti. V beljakovinah, celicah, biomembranah in organizmih se bodo proučevale kompleksne biološke strukture in njihovo delovanje. Obravnavani bodo nanotehnološki in biomimetični pristopi za testiranje biofizikalnih struktur in procesov. Študenti bodo pridobili osnovna znanja in izkušnje pri iskanju strokovne literature v nastajajočem interdisciplinarnem področju, kar jim bo omogočilo nadaljnje raziskovanje/nadgrajevanje z izvedbo lastnih raziskovalnih projektov.

The course introduces selected contemporary topics at the interface between biophysics and micro- and nanoscale physics. At the same time, research activities at the Laboratory for Water Biophysics and membrane processes (LWB) are introduced. Complex biological structures and their function are studied, ranging from proteins, cells, biomembranes to organisms. Nanotechnological and biomimetic approaches for probing biophysical structures and processes will be discussed. Participants will obtain the basic knowledge and skills for understanding the research literature in an emerging interdisciplinary field and will be able to consider and perform future research projects of their own.



Znanje in razumevanje: Z osvojenimi cilji bo študent lahko:

• razumel in uporabljal podatkovne baze biomolekurnih struktur in zaporedij

• pojasnil celično sestavo odgovorno za mehanske lastnosti celic

• opredelil strukturne in funkcionalne elemente biomembran

• obrazložil transportne pojave skozi membrano, vključno z difuzijo, aktivnim transportom, pospešenim transportom in osmotskim transportom

• pojasnil osnovni koncept toka tekočine v mikro-merilu

bral, razumel in predstavil sodobne interdisciplinarne raziskovalne članke s področja biofizike, biotekočin in biomimetike

A student who has met the objectives of the course will be able to: • Understand and use databases of bio-molecular

structures and sequences • Explain the cellular constituents responsible for

mechanical properties of cells • Explain defining structural and functional

elements of biomembranes • Explain membrane transport phenomena

including barrier diffusion, active transport, facilitated transport and osmotic transport

• Explain the basic concepts of fluid flow at the micrometer scale

Read, understand and present contemporary interdisciplinary research articles in the field of biophysics, biofluidics, and biomimetics.

86


Predavanja, učenjev skupinah na določenih nalogah/problemih in pisanje poročil.

Lectures, problem based learning in groups, and writing report.



Assessment:


Ustni izpit

Projektno poročilo

50 50


Oral exam

Project report


Nielsen, C.H. Biomimetic membranes for sensor and separation applications. Anal. Bioanal. Chem. 395, 697-718, 2009.

Nielsen, C.,H. Protein-lipid interactions in Biological Membranes. In Bohr, H. (ed.) Handbook of Molecular Biophysics, 329-358, Wiley-VC Berlin, Germany, 2009. ISBN-10: 3527407022.

Hélix-Nielsen, C. Biomimetic membranes for sensor and separation applications. Springer Verlag ISBN 978-94-007-2183-8, 2012.

87

Novi biotehnološki pristopi in aplikacije


Predmet: Novi biotehnološki pristopi in aplikacije

Course title: Novel Biotechnological Approaches and Applications




Semester Semester


2. Zimski

Autumn



Predavanja Lectures

Seminar Seminar

Sem. vaje Tutorial


work



ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Martin Koller

Jeziki / Languages:

Predavanja / Lectures: angleščina / English

Vaje / Tutorial: angleščina / English


Prerequisits:

Ni. None.

Vsebina:


Izbrana poglavja iz mikrobiologije in osnov tehnologije čistih prostorov (Cleanroom)

Mikrobiološki razvoj in mikrobiološka sistematika; “Drevo življenja”

Gibljivost mikrobov (kemotaksa, aerotaksa, magnetotaksa, bički itd.

Mikrobiološke strategije za pridobivanje biomase in energije (autotrofni in heterotrofni organizmi, metabolične poti itd.)

Vloga mikrobov pri naravnem ciklu kemijskih elementov (C, O, N, P, S)

Antibiotiki: razredi, različni akcijski mehanizmi, tveganja in izzivi

Principi načrtovanja čistih prostorov (Clean-rooms): definicija, različni razredi in nivoji istih prostorov

Rizične skupine mikrobov: ravnanje in zakonski predpisi

Selected Chapters of Microbiology and Basics of Cleanroom Engineering

Microbial evolution and microbial systematic;

Tree of Life

Motility of microbes (chemotaxis, aerotaxis, magnetotaxis, flagellates, etc.)

Microbial strategies for biomass- and energy generation (autotrophic and heterotrophic organisms, metabolic pathways, etc.)

The role of microbes in the natural cycles of the chemical elements (C, O, N, P, S)

Antibiotics: Classes, different mechanisms of action, risks and challenges

Principles of Cleanroom Engineering: Definition and different classes and levels of cleanrooms

Risk groups of microbes: Handling, Legislative conditions

New Approaches to Industrial Biotechnology

88

Novi pristopi k Industrijski biotehnologji (“Bela biotehnologija”)

Izbrani biotehnološki produkti narekujejo uporabo industrijskih odpadkov in presežnih materialov, kot npr. sirotke iz mlečne industrije, stranskih produktov iz proizvodnje biodizla, odpadnih maščob rastlinskega in živalskega izvora, (ligno)celuloza

Podrobnosti: razpoložljivost surovin v odvisnosti od globalne regijske in sezonske razpoložljivosti, izzivi in posebnosti pri njihovi pripravi in presnovi, ter perspektive tržnega uvajanja produktov

Poli(hidroksialkanoati) (PHA) kot biotehno-logična alternativa za sodobno proizvedene tehnomere (termoplaste in elastomere): genetske, encimske, metabolične in tehnološke osnove, tehnike; izzivi pri separacijah teh materialov in njihova uporaba za specialne produkte (farmacevtske, medicinske, agro-industrijske itd…) - posebno poglavje: autotrofna, miksotrofna

in heterotrofna proizvodnja poli(hidroksi-alkanoatov) z izbranimi fototrofnimi mikrobi

- posebno poglavje: pilotna in industrijska proizvodnja PHA iz različnih biogenih surovin; primeri različnih globalnih regij

- posebno poglavje: novi procesno tehnološki pristopi za proizvodnjo PHA za izboljšanje kvalitete in kvantitete proizvodnje biopolimerov (npr. večstopenjski kontinuirni procesi) in razvoj novih vrst biogenih tehnomerov, npr. blok polimerov

Primarni in sekundarni produkti iz extremophile archaea (pigmenti, specialni ogljikovodiki, inertni citoplazmatski produkti, halocini)

Prokariotski mikrobi s sposobnostjo tvorjenja spor kot proizvajalci različnih ciljnih produktov (biotehnološki aceton, izopropanol, nastanek butanola, proizvodnja insekticidov z bacilli) Podrobnosti: posebnosti gojenja takšnih sevov, kinetične značilnosti tvorbe produktov, prednosti in slabosti v primerjavi s kemijsko proizvodnjo

Biovodik kot nosilec prihodnje zelene energije: Biotehnološka proizvodnja, izzivi, perspektiva in primerjava z drugo, tretjo in četrto generacijo biogoriv

Napredne filtracijske tehnike za industrijske biotehnološke aplikacije (membrane iz votlih vlaken za mikro-, ultra-, nanofiltracijo in reverzno ozmozo)

(White Biotechnology)

Selected biotechnological products form the application of industrial waste- and surplus materials feedstock, namely: whey from dairy industry, side streams from the biodiesel production, waste lipids of phytal and animal origin, (Ligno)cellulosics Details: Availability of the raw materials in dependence on the global region and seasonal availability, challenges and particularities in their upstream processing and conversion, and perspectives of market penetration of the products

Poly(hydroxyalkanoates) (PHAs) as biotechno-logical alternative for contemporarily produced technomers (thermoplasts and elastomers): Genetic, enzymatic, metabolic and engineering Fundamentals, techniques; challenges in downstream processing of these materials, and their application for bulk and niche products (packaging, pharmaceutical, medical, agro-industrial, etc.). - Special section about: Autotrophic,

mixotrophic and heterotrophic production of poly(hydroxyalkanoates) by selected phototrophic microbes

- Special section about: Pilot- and industrial scale production of PHA starting from different biogenic feedstocks; case studies from different global regions

- Special section about: New process engineering aproaches for PHA production to enhance quality and quantity of biopolymer production (e.g. multistage-continuous processes), and to design new types of biogenic technomers (e.g. blockpolymers)

Primary and secondary products from extremophile archaea (pigments, special carbohydrates, inert cytoplasmatic compounds, halocins)

Sporeforming prokaryotic microbes as producers of various bulk- and niche products (biotechnological acetone, isopropanol, butanol formation, production of insecticides by Bacilli. Details: Particularities in the cultivation of such production strains; kinetic particularities of product formation, advantages and disadvantages in comparison to chemical production.

Biohydrogen as a future-oriented »green energy carrier«: Biotechnological production, challenges, prospective, and comparison to other 2nd, 3rd, and 4th generation biofuels.

Advanced filtration techniques for large-scale biotechnological application (Hollow fiber

89

Laboratorijske vaje:

Splošno ravnanje z bioreaktorji

Gojenje kvasovk v bioreaktorju (regulacija procesa in analiza kinetike)

Gojenje izbranega biopoliestra (PHA) za proizvodnjo prokariontskih vrst v bioreaktorju (regulacija in zaključni procesi za čiščenje produkta, analiza kinetike)

Gojenje fototrofnih mikroalg v fotobioreaktorju (regulacija, analiza kinetike, zaključni procesi za čiščenje olj iz mikroalg kot potencialne surovine za biodizel 3. generacije)

Določanje celične mase v tekočih kulturah (centrifuguranje, filtracija, liofilizacija, infrardeča bilanca itd.)

Barvanje celic za ponazoritev organel in inkluzij (jedra, spore, inertne citoplazemske inkluzije, bički)

membranes for micro-, ultra-, nanofiltration and reversed osmosis)

Labor work

General handling of bioreactors

Cultivation of yeast in bioreactor (together with process control, and kinetic analysis)

Cultivation of a selected biopolyester (PHA) producing prokaryotic species in bioreactor (together with process control, downstream processing for product recovery, and kinetic analysis)

Cultivation of a selected phototrophic microalgal species in photobioreactor (together with process control, kinetic analysis, and downstream processing for recovery of microalgal oil as potential 3rd-generation biodiesel feedstock

Determination of cell mass in liquid cultures (centrifugation, filtration, lyophylization, infrared balance etc.)

Cell staining for visualization of organelles and inclusions (nucleus, spores, inert cytoplasmatic inclusions, flagella)


Scriptum provided by lecturer

Selected original (primary and secondary) literature provided by lecturer (also own publications)

Koller, M.: Designs of Closed Photobioreactors for Algal Cultivation. – in: Algal Biorefeneries Vol. II (submitted; publication expected in 2015) (Springer; book chapter)


Koller, M.; Salerno, A.; Braunegg, G. (2013): Polyhydroxyalkanoates: Basics, Production and Applications of Microbial Biopolyesters. - book: Bio-based Plastics: Materials and Applications, pp. 137 – 170 (Wiley)

Koller, M.; Salerno, A.; Muhr, A.; Reiterer, A.; Braunegg, G. (2013): Polyhydroxyalkanoates: Biodegradable polymeric materials from renewable resources. Materiali in Tehnologije = Materials and Technology 47(1), 5–12



Študent bo pridobil naslednja znanja:

pilotna in idustrijska biotehnologija za veliko-kapacitetne in nišne produkte

obnovljive surovine za industrijske bioproizvode in uporaba industrijskih presežkov v biotehnologiji

analize kinetike na osnovi podatkov, pridobljenih v bioprocesu in končna ocena procesa

zaključni procesi za pridobivanje industrijsko pomembnih intracelularnih bioproduktov.

The main objective is devoted to knowledge in

Pilot- and Industrial scale biotechnology for bulk- and niche products

Renewable raw materials for industrial bioprodcts with special emphasis on industrial surplus streams to be upgraded to feedstocks for biotechnology

Kinetic analysis of own elaborated raw data from bioprocess and final process evaluation

Downstream processing for recovery of industrially relevant intracellular bioproducts

90




Vrste bioproduktov in substratov ter mikrobov za njihovo proizvodnjo

Mikrobne strategije za proizvodnjo biomase in energije

Osnovno znanje o antibiotikih

Gojenje različnih mikrobov v laboratorijskem bioreaktorju, spremljanje, nadzor in ocean vrednotenje procesa


razumevanje prednosti, slabosti in izzivov bioproizvodnje

razumevanje celovitih okoljskih in ekonomskih vplivov kemijske in biokemijske proizvodnje

razumevanje različnih zahtev različnih mikrobov

seznanitev z industrijsko pomembnimi mikroorganizmi.


Range of different bioproducts and accessible substrates and microbes to produce them

Microbial strategies for biomass- and energy production

Basic knowledge about antibiotics

Performing cultivation of different microbes in laboratory bioreactors with accompanying process monitoring and subsequent process evaluation


Understanding the advandages, drawbacks, and challenges of bio-based production.

Understanding the holistic environmental and economic impacts of chemical vs. biochemical production strategies

Understanding different requirements of different microbes

Getting familiar with industrially relevant microorganisms


predavanja

samostojno seminarsko delo za končno ustno predstavitev laboratorijskih rezultatov (skupinsko ali posamezno)

samostojno seminarsko delo za ustno predstavitev izbrane izvirne literature (skupinsko ali posamezno)

samostojno učenje

Lectures

Independent seminar work for final oral presentation of laboratory results (group or single)

Independent seminar work for oral presentation of selected original literature (group or single)

Self-learning



Assessment:


Pisni izpit

Ustna predstavitev laboratorijskih rezultatov

Ustna predstavitev izbranih tem

Izvedba kinetične analize eksperimentalnih podatkov, pridobljenih v izvedenem bioprocesu

Aktivno sodelovanje

25 12,5

12,5 25

25


Final written examination

Oral presentation of own laboratory results

Oral presentation on selected topics

Evaluation of kinetic analysis of own experimental raw data from the accomplished bioprocesses

Active collaboration


Koller, M.; Chiellini, E., Braunegg, G. (2015): Study on the production and re-use of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and extracellular polysaccharide by the archaeon Haloferax mediterranei strain DSM 1411 Chemical and Biochemical Engineering Quarterly 29(2); in press.

Koller, M.; Muhr, A., Braunegg, G. (2014): Microalgae as versatile cellular factories. Algal Research 6(A), 53-63.

Koller, M.; Bona, R.; Braunegg, G.; Hermann, C.; Horvat, P.; Kroutil, M.; Martinz, J.; Neto, J.; Varila, P.; Pereira, L. (2005): Production of polyhydroxyalkanoates from agricultural waste and surplus materials. Biomacromolecules 6(2), 561–565.

91

FP 7 EU-Project ANIMPOL ‘Biotechnological conversion of carbon containing wastes for eco-efficient production of high added value products’ (Grant number 245084): Coordinator and Person in charge for the administrative, financial, scientific and technical aspects of the project (2010-2013): Most relevant references:

Muhr, A.; Rechberger, E. M.; Salerno, A.; Reiterer, A.; Schiller, M.; Kwicien, M.; Adamus, G.; Kowalczuk, M.; Strohmeier, K.; Schober, S.; Mittelbach, M.; Koller, M. (2013): Biodegradable latexes from animal-derived waste: Biosynthesis and characterization of mcl-PHA accumulated by Ps. citronellolis. Reactive & Functional Polymers 73(10), 1391–1398

Shahzad, K.; Kettl, K.-H.; Koller, M.; Titz, M.; Schnitzer, H.; Narodoslawsky, M. (2013): Comparison of ecological footprint for biobased PHA production from animal residues utilizing different energy resources. Clean Technologies and Environmental Policy 15(3), 525–536

92

Encimske tehnologije


Predmet: Encimske tehnologije

Course title: Enzyme Technologies




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6


Jeziki / Languages:




Prerequisites:

Potrebno je znanje iz bioseparacijske tehnike in biokatalize ter industrijske mikrobiologije.

Knowledge of bioseparation processes and biocatalysis and industrial microbiology is needed.

Vsebina:


Izolacija in priprava encimov. Imobilizacija. Uporaba encimov (detergenti, tekstilije, papir, živalska krma). Encimi kot biokatalizatorji (osnovne kemikalije, fine kemikalije, hrana, farmacevtske učinkovine). Farmacevtska aplikacija biokatalize (inhibicija encimov za boj proti boleznim, specifične biokatalizne reakcije v farmaciji). Sintetični encimi. Laboratorijske vaje na konkretnem primeru biokatalizirane proizvodje osnovnih in finih kemikalij ter postopka priprave encimov.

Isolation and preparation of enzymes. Imobilization. Application of enzymes (detergents, textilles, pulp and paper, animal feed). Application of enzymes as biocatalysts (basic chemicals, fine chemicals, food, pharmaceuticals). Pharmaceutical application of biocatalysis (enzyme inhibition for the fight against disease, specific biocatalytic reactions in pharma). Artificial enzymes. Laboratory work on the case of biocatalytic production of basic and fine chemicals, as well as on preparation of enzymes.

93


S. Bommarius, B. R. Riebel-Bommarius, Biocatalysis: Fundamentals and Applications, 1st ed., Wiley-VCH; Darmstadt, 2004.

Liese, K. Seelbach, C. Wandrey, Industrial Biotransformations, Wiley-VCH, Weinheim, 2000.


J. A. Tao, R. J. Kazlauskas, Biocatalysis for Green Chemistry and Chemical Process Development, Wiley, ISBN: 978-0-470-43778-0, 2011.


A. Illanes, L. Wilson, C. Vera, Problem Solving in Enzyme Biocatalysis, Wiley, ISBN: 978-1-118-34171-1, 2013.



Pregled metod izolacije in čiščenja encimov ter aplikacija posameznih encimov v biotransformacijah.

Overview of enzyme isolation and purification methods and application of enzymes in biotransformations.



Znanje in razumevanje: Poznavanje proizvodnje encimov, njihove stabilnosti in produktivnosti ter uporabe v biosintezi.

Knowledge and Understanding: Knowledge of enzyme production, their stability and productivity, as well as their application in biosynthesis.






Lectures in lecture room, equipped with audio-visual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on a selected case.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijsko delo - seminarska naloga - ustni izpit

30 30 40

Student has to pass successfully the following obligations: - laboratory work - seminary work - oral examination

94





ŠULEK, Franja, KNEZ, Željko, LEITGEB, Maja. Immobilization of cholesterol oxidase to finely dispersed silica-coated maghemite nanoparticles based magnetic fluid. Applied Surface Science, ISSN 0169-4332. 2010, 256 (14), 4596-4600. [COBISS.SI-ID 14055446]


95

Sodobna biokataliza


Predmet: Sodobna biokataliza

Course title: Modern biocatalysis




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6


Jeziki / Languages:




Prerequisites:

Potrebno je znanje iz bioseparacijske tehnike in biokatalize ter industrijske mikrobiologije.

Knowledge of bioseparation processes, biocatalysis and industrial microbiology is needed.

Vsebina:


Encimi v organskih topilih (prednosti, bifazne reakcije, separacija, stabilnost encimov, selektivnost encimov). Prednosti biokatalize v organskih topilih. Korelacija med delovanjem encimov in parametri topila (variacija hidrofobnosti – log P, enantioselektivnost in polarnost topila ter hidrofobost). Optimalno rokovanje z encimi v organskih topilih. Novejši reakcijski mediji za biokatalizo (substrat kot topilo, superkritični fluidi, ionske tekočine, emulzije, mikroemulzije, tekoči kristali). Topilo kot parameter za optimiranje reakcije (»medium engineering«). Laboratorijske vaje iz področja encimsko kataliziranih reakcij v nekonvencionalnih medijih, npr. v plinih visoke gostote, ionskih tekočinah, …

Enzymes in organic solvents (advantages, biphasic reactions, separation, enzyme stability, selectivity of enzymes). Advantages of biocatalysis in organic solvents. Correlation between enzyme performance and solvent parameters (variation of hydrophobicity – log P, enantioselectivity and solvent polarity and hydrophobicity). Optimal handling of enzymes in organic solvents. Novel reaction media for biocatalysis (substrate as a solvent, supercritical fluids, ionic liquids, emulsions, microemulsions, liquid crystals). Solvent as a parameter for reaction optimization (»medium engineering). Laboratory work in the field of enzymatic reactions in nonconventional media, e.g. supercritical fluids, ionic liquids, etc.

96


A. S. Bommarius, B. R. Riebel-Bommarius, Biocatalysis: Fundamentals and Applications, 1st ed., Wiley-VCH; Darmstadt, 2004.

K. Faber, Bio-transformations in Organic Chemistry, 6th ed., Springer-Verlag, Berlin, 2011.


P.G. Jessop, W. Leitner, Chemical Synthesis Using Supercritical Fluids, Wiley-VCH, Weinheim, online 2007.

P. Wasserscheid, T. Welton, Ionic Liquids in Synthesis, 2nd ed., Wiley-VCH, Weinheim, 2007.


Pregled možnih alternativnih topil za biokatalitične transformacije.

Overview of possible alternative solvents for biocatalytical transformations.



Znanje in razumevanje: Zmožnost načrtovanja biokataliziranih reakcij v topilih, ki niso voda.

Knowledge and Understanding: Design of biocatalytical reactions in solvents, others than water.






Lectures in a lecture room, equipped with audio-visual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on selected case.



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje - ustni izpit

40 60

Student has to pass successfully the following obligations: - laboratory work - oral examination





KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN 0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406]

97

Farmacevtske učinkovine


Predmet: Farmacevtske učinkovine

Course title: Active Pharmaceutical Ingredients




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Igor Simonič

Jeziki / Languages:




Prerequisites:

Pogojev ni. None.


- Farmacevtske učinkovine – neformulirana zdravila; klasifikacije in terminologija.

- Ekonomski, socialni in strateški vidiki zdravil oz. farmacevtskih učinkovin.

- Posebne zahteve in predpisi – učinkovitost, varnost; sistemi kakovosti, dobre prakse v razvoju, proizvodnji in kontroli farmacevtskih učinkovin, validacijske tehnologije; registracijske zahteve in dokumentacija.

- Pomen in vplivi fizikalno-kemijskih lastnosti na učinkovitost in varnost; specifikacije kakovosti; vsebnost, čistota, viri in vrste nečistot, strategije obvladovanja nečistot, fizikalni in drugi parametri, stabilnost.

- Principi razvoja proizvodnih in kontrolnih tehnologij za farmacevtske učinkovine.

- Trendi v razvoju in proizvodnji farmacevtskih učinkovin.

- Principi, značilnosti in pomen patentne zaščite

- Active pharmaceutical ingridients (API) – nonformulated drugs; clasifications and terminology.

- Economic, social and strategic aspects of drugs, including API.

- Specific requirements and regulations – efficacy and safety; quality systems, good practices in development, production and quality control of API, validation technologies; requirements for registrations and documentation.

- Significance of physico-chemical parameters on efficacy and safety; quality specifications; assay, purity, sources and types of impurities, strategies of mastering impurities, physical and other parameters, stability.

- Principles of development of production and quality control technologies for API.

- Trends in development and production of API. - Principles, characteristics and significance of

98

za farmacevtske učinkovine. - Biotehnološke – klasične in rekombinantne,

sintetske in polsintetske učinkovine – značilni primeri učinkovin in tehnologij; značilni terapevtski in strukturni tipi.

patent protection of API. - Biotechnological – classic and recombinant,

synthetic and semisynthetic API – characteristic examples of substances and technologies; characteristic therapeutic and structural types.


B. Štrukelj (ur.), J. Kos (ur.), Biološka zdravila: od gena do učinkovine, Slovensko farmacevtsko društvo, Ljubljana, 2007.


J. J. Li, D. S. Johnson, D. Sliskovic, B. D. Roth: Contemporary drug synthesis, John Wiley & Sons, Inc., Hoboken, New Jersey, 2004.

O. Repič: Principles of process research and chemical development in the pharmaceutical industry, John Wiley & Sons, Inc., New York, Chichester, Weinheim, Brisbane, Singapore, Toronto, 1998.

M. M. Amiji, B. J. Sandmann: Applied physical pharmacy, McGraw-Hill Co. Inc., New York, 2003.

European Pharmacopoeia, 4th Edition, EDQM, Strasbourg, 2004 (in druge izdaje ter dodatki).



Študent spozna in razume specifične zahteve za farmacevtske učinkovine ter multidisciplinarnost obvladovanja tega področja; pridobi ključna znanja za načrtovanje in razvoj proizvodnih in kontrolnih tehnologij ter obvladovanje proizvodnje farmacevtskih učinkovin. Usposobi se za delo v timih s strokovnjaki na področju zdravil.

Student acknowledges and understands specific requirements for API and multidisiplinariness of the field; acquires crucial expertise for planning and developing production and quality control technologies, as well as mastering API production. Student gets qualified for team work in the field of drugs.


Znanje in razumevanje: Študent pozna osnovno terminologijo in klasifikacije, ključne strukturne in terapevtske tipe učinkovin ter značilne tehnologije. Pozna principe in postopke razvoja tehnologij za učinkovine. Razume pomen in medsebojne vplive parametrov kakovosti in jih zna specificirati. Razume principe sistemov kakovosti v razvoju, kontroli kakovosti in proizvodnji. Pozna osnovne predpise za učinkovine ter osnove zaščite intelektualne lastnine in pomen za delo na področju zdravil.

Knowledge and Understanding: Student is familiar with basic terminology and clasifications, crucial structural and therapeutic types of API, as well as characteristic technologies; knows principles and procedures of production and quality control technologies development for API. Uderstands signifiacance and correlations of quality parameters, and is familiar with approaches to determine them. Student understands principles of quality sistems in development, quality control and production of API, and is aware of relevant regulations, as well as of IPR and its relevance for working in the field.

Prenesljive/ključne spretnosti in drugi atributi: Študent razvije sposobnost integracije znanj ter reševanja kompleksnih interdisciplinarnih problemov.

Transferable/Key Skills and other attributes: Student develops ability to integrate his knowledge, and to solve complex interdisciplinary problems.



Predavanja, seminarske vaje, projektno delo. Lectures, tutorial and project work.

99



Assessment:


- projektno poročilo - pisni izpit

50 50

Student has to pass successfully the following obligations: - project report - written examination


1. SIMONIČ, Igor, BENKIČ, Primož, ZUPET, Rok, SMRKOLJ, Matej, ŠTUKELJ, Mitja. Process for the synthesis of clopidogrel and new forms of pharmaceutically acceptable salts thereof : EP2078025 B1. München: European Patent Office, 2016. 9 str., ilustr. https://worldwide.espacenet. com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20090715&CC=EP&NR=2078025A2&KC=A2#. [COBISS.SI-ID 4281969] patentna družina: Application number: 07820533.3; Int. appl. no.: PCT/EP2007/060127; Int. appl. no.:WO 2008/034912

2. SIMONIČ, Igor, BENKIČ, Primož, VAJS, Anamarija, KRAMAR, Andrejka, ŠTIMAC, Anton. Process for preparing crystalline form II of orlistat : EP1973893 B1. München: European Patent Office, 2016. 9 str., ilustr. https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=EP&NR=1973893B1&KC=B1&FT=D&ND=&date=20150429&DB=&locale=#. [COBISS.SI-ID 4284529] patentna družina: Application number: EP20060841172 20061227; Int. appl. no.: PCT/EP2006/012544; Int. appl. no.:WO 2007/073937

3. SIMONIČ, Igor. Izvajanje uredbe CLP v farmacevtski industriji : Primerjava razvrščanja in označevanja nekaterih farmacevtskih učinkovin = The Implementation of CLP in the pharmaceutical industry : Comparison of classification and labelling of certain pharmaceutical ingredients. V: GORENC ZORAN, Annmarie (ur.). Tehnologija v dobi trajnostnega razvoja : zbornik povzetkov = Technology in the era of sustainable development : conference proceedings abstracts. Novo mesto: Fakulteta za industrijski inženiring. 2016, str. 25-26. http://rii.fini-unm.si/wp-content/uploads/2016/04/Zbornik-povzetkov-konference_FINAL-WEB.pdf. [COBISS.SI-ID 1181942]

4. SIMONIČ, Igor. The Implementation of CLP in the pharmaceutical industry : Comparison of classification and labelling of certain pharmaceutical ingredients = Izvajanje uredbe CLP v farmacevtski industriji : Primerjava razvrščanja in označevanja nekaterih učinkovin. V: CROITORESCU, Valerian, GORENC ZORAN, Annmarie. Technology in the era of sustainable development : scientific monograph = Tehnologije v dobi trajnostnega razvoja : znanstvena monografija. Novo mesto: Fakulteta za industrijski inženiring: = Faculty of Industrial Engineering. 2016, str. 130-144, tabele. [COBISS.SI-ID 1225462]

5. KOTAR-JORDAN, Berta, LENARŠIČ, Roman, GRČMAN, Marija, SMRKOLJ, Matej, MEDEN, Anton, SIMONIČ, Igor, ZUPET, Rok, GNIDOVEC, Jože, BENKIČ, Primož. Isopropanol water solvate of olanzapine : US7906642 B2 - 2011-03-11. [Alexandria]: United States Patent and Trademark Office, 2011. 10 str., ilustr. https://www.google.ch/patents/US7906642. [COBISS.SI-ID 4281201] patentna družina: PCT No.: PCT/EP2005/002389; PCT Pub. No.: WO2005/085256; Patent No.: US 7,906,642 B2; Appl. No.: 10/591,831; EP 1730153 (B1), 2011-07-20

6. KOTAR-JORDAN, Berta, LENARŠIČ, Roman, GRČMAN, Marija, SMRKOLJ, Matej, MEDEN, Anton, SIMONIČ, Igor, ZUPET, Rok, GNIDOVEC, Jože, BENKIČ, Primož. Isopropanol water solvate of olanzapine : EP1730153 (B1). München: European Patent Office, 2011. 18 str., ilustr. https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=EP&NR=1730153B1&KC=B1&FT=D&ND=&date=20110720&DB=&locale=#. [COBISS.SI-ID 4281713] patentna družina: Application number: EP20050707723 20050307; Appl. no.: 05707723.2; Int. appl. no.: PCT/EP2005/002389; US 7906642 (B2), 2011-03-11

7. KOTAR-JORDAN, Berta, SIMONIČ, Igor, ZUPET, Rok, RUŽIČ, Miloš, GRČMAN, Marija, PEČAVAR, Anica. Crystallisation of solid forms of clopidogrel addition salts : EP 1656381 B1 : patent. München: European Patent Office, 2011. 15 str., ilustr. https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110616&DB=EPODOC&locale=en_EP&CC=PT&NR=1656381E&KC=E&ND=4#. [COBISS.SI-ID 4281457] patentna družina: International publication number: WO2005016931 (A2); Application number: PCT/EP2004/008989; Original document: SI1656381 (T1) - 2011-07-29

100

8. ZUPANČIČ, Vinko, SMRKOLJ, Matej, BENKIČ, Primož, SIMONIČ, Igor, PLEVNIK, Miha, RITLOP, Gregor, KRISTL, Albin, VREČER, Franc. Preformulation investigation of some clopidogrel addition salts. Acta chimica slovenica, ISSN 1318-0207. [Tiskana izd.], 2010, vol. 57, no. 2, str. 376-385. [COBISS.SI-ID 2822769]

9. SIMONIČ, Igor. Photochemical aromatization of Hantzsch by nitrats. V: STANOVNIK, Branko (ur.), SVETE, Jurij (ur.). Program. Abstracts of papers. List of participants, 13th Blue Danube Symposium on Heterocyclic Chemistry, Bled, September 20-23 2009, Slovenia. Ljubljana: Organizing Committee of the 13th Blue Danube Symposium on Heterocyclic Chemistry. 2009, str. 125. [COBISS.SI-ID 3193457]

10. SIMONIČ, Igor, ZUPANČIČ, Silvo, GOLOBIČ, Amalija, GOLIČ, Ljubo, STANOVNIK, Branko. The crystal structure of lacidipine phototransformation product. Acta chimica slovenica, ISSN 1318-0207. [Tiskana izd.], 2008, vol. 55, no. 2, str. 458-461. http://acta.chem-soc.si/55/55-2-458.pdf. [COBISS.SI-ID 29570053]

11. ZUPANČIČ, Vinko, SMRKOLJ, Matej, BENKIČ, Primož, SIMONIČ, Igor, RITLOP, Gregor, KRISTL, Albin, VREČER, Franc. Characterization of different clopidogrel addition salts. V: MRHAR, Aleš (ur.), BAUMGARTNER, Saša (ur.). 7th Central European Symposium on Pharmaceutical Technology and Biodelivery Systems, September 18-20, 2008, Hotel Mons, Ljubljana, Slovenia : Proceedings from the Symposium, (Farm. vestn., ISSN 0014-8229, Let. 59, special iss.). Ljubljana: Slovenian Pharmaceutical Society. 2008, str. 308-309. [COBISS.SI-ID 2751857]

101

Farmacevtska tehnika


Predmet: Farmacevtska tehnika

Course title: Pharmaceutical Technology




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6


Jeziki / Languages:




Prerequisites:

Znanje iz splošne kemije, analizne in fizikalne kemije. Osnove iz mehanike fluidov in prenosnih pojavov.

Knowledge on basic chemistry, analytical and physical chemistry. Basics of fluid mechanics and mass transfer.


Farmacevtsko tehnološke operacije:

fizikalno kemijske osnove pri načrtovanju farmacevtske oblike (difuzija, adhezija, kohezija, absorpcija, porazdelitev in sproščanje, prenos snovi idr.),

osnovne tehnološke operacije (mešanje, mletje, postopki s superkritičnimi fluidi, filtriranje, suspendiranje, steriliziranje, liofiliziranje idr.),

splošni vidiki pri načrtovanju farmacevtske oblike (stabilnost in stabilizacija, nekompatibilnosti, materiali in postopki za embalažo, sterilizacija),

razvite farmacevtske operacije,

stabilnost zdravil. Farmacevtske oblike:

Pharmaceutical technology operations:

Physico-chemical basics of designing pharmaceutical forms (diffusion, adhesion, cohesion, absorbtion, distribution and elimination of drugs, mass transfer and others),

Basic technology operations (mixing, grinding, processes with supecritical fluids, filtration, suspension, sterilization, liophilization and others),

Basic aspects for designing pharmaceutical forms (stability and stabilization, uncompatibility, materials and processes for packaging, sterilization),

Advanced pharmaceutical operations,

Drug stability. Pharmaceutical forms:

102

teoretične osnove farmacevtskih oblik kot aplikacijskega in disperzijskega sistema (osnovne in pomožne substance pri načrtovanju farmacevtskih oblik),

statične metode pri načrtovanju farmacevtkih oblik,

osnove biofarmacije, farmacevstke oblike: trdne, poltrdne, tekoče,

plinaste (oblike za inhaliranje), rastlinski izvlečki idr.,

sodobne oblike zdravil in tendenca razvoja (terapevtski sistemi, potencialne oblike zdravil).

Laboratorijske vaje: Študentje spoznajo osnovne farmacevtsko tehnološke operacije (mešanje, mletje, drobljenje, postopki s superkritičnimi fluidi, kompaktiranje, emulgiranje…) in sodobno načrtovanje, oblikovanje in vrednotenje trdnih oblik s poudarkom na izboru pomožnih snovi.

Theoretical basics of pharmaceutical forms as an application and dispersion system (basic and auxiliary substances at design of pharmaceutical forms),

Static methods for designing pharmaceutical forms,

Basics of biopharmacy, Pharmaceutical forms: solids, semi-solids,

liquids, gasses (inhalation forms), natural material extracts and others,

Modern forms of pharmaceutics and development tendency (therapeutic systems, potential pharmaceutical forms).

Laboratory work: Students become familiar with basic pharmaceutical technological operations (mixing, grinding, crushing, processes with supercritical fluids, compaction, emulsification,…) and modern designing, formulation and evaluation of solid forms with emphasis on suppository substance selection.


Voigt R., Pharmazeutische Technologie für Studium und Beruf, 11., durchgesehene und ergänzte Auflage 2010. XXIII, 746 S., 317 s/w Abb., 110 s/w Tab., gebunden, Deutscher Apotheker Verlag, ISBN 978-37692-5003-9, 2010.


Roshni L. Dutton, Jeno M. Scharer, Jeno M. Scharer, Advanced Technologies for Biopharmaceutical Processing, Blackwell Pub Professional, ISBN-10: 0813805171, 2006.



Znanje o novih materialih, tehnoloških pristopih in farmacevtskih oblikah.

Knowledge on new materials, technology approaches in pharmaceutical forms.



Znanje in razumevanje: Znanje s področja osnovnih tehnoloških operacij in formuliranja farmacevtskih oblik.

Knowledge and Understanding: Knowledge in the field of basic technological operations and formulation of pharmaceutical forms.

Prenesljive/ključne spretnosti in drugi atributi: Vsebina predmeta je povezana z ostalimi predmeti na smeri Biokemijska tehnika.

Transferable/Key Skills and other attributes: The subject is connected to other subjects in the option Biochemical engineering.




- lectures - laboratory work.

103



Assessment:


- laboratorijske vaje - pisni izpit - ustni izpit

10 50 40


- laboratory work - written examination - oral examination


VERONOVSKI, Anja, NOVAK, Zoran, KNEZ, Željko. Synthesis and use of organic biodegradable aerogels as drug carriers. Journal of biomaterials science, Polymer edition, ISSN 0920-5063, 2012, vol. 23, no. 7, str. 873-886.

LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko. Biocompatible nanomaterials : synthesis, characterization and applications. V: ACKLIN, Beate (ur.), LAUTENS, Edon (ur.). Magnetic nanoparticles : properties, synthesis and applications, (Physics research and technology), (Nanotechnology science and technology). New York: Nova Science Publishers, 2012, str. 135-156.

CÖR, Darija, BOTIĆ, Tanja, KNEZ, Željko, BATISTA, Urška, GREGORI, Andrej, POHLEVEN, Franc, BONČINA, Tonica. Two-stage extraction of antitumor, antioxidant and antiacetylcholinesterase compounds from Ganoderma lucidum fruiting body. The Journal of supercritical fluids, ISSN 0896-8446, 2014, vol. 91, str. 53-60, doi: 10.1016/j.supflu.2014.04.006.

LEITGEB, Maja, HOJNIK PODREPŠEK, Gordana, KNEZ, Željko. Magnetic nanocarriers for targeted drug delivery. V: SABBAS, Nora P. (ur.). Magnetic nanoparticles : synthesis, physicochemical properties and role in biomedicine, (Nanotechnology science and technology). New York: Nova Science Publishers, 2014, str. 201-230.

KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca. Industrial applications of supercritical fluids: a review. Energy, ISSN 0360-5442, 2014, str. 1-9, doi: 10.1016/j.energy.2014.07.044.

104

Biokemija, mikrobiologija in molekularna biologija


Predmet: Biokemija, mikrobiologija in molekularna biologija

Course title: Biochemistry, Microbiology and Molecular biology




Semester Semester



2. zimski

Autumn



Predavanja


Sem. vaje Tutorial




ECTS

15 15 150 6

Nosilec predmeta / Lecturer: Uroš Potočnik, Maja Leitgeb

Jeziki / Languages:

Predavanja / Lecture: slovenščina / Slovene

Vaje / Tutorial: slovenščina / Slovene


Prerequisites:

Osnovna znanja iz mikrobiologije. Basic knowledge of microbiology.


Morfologija mikroorganizmov. Celična struktura. Struktura in funkcija celičnih membran. Celična stena prokariot. Struktura in funkcija subcelularnih organel. Razmnoževanje mikroorganizmov. Komunikacija med celicami in prenos signalov Proteini: struktura in vloga v bioloških procesih, analiza plazemskih proteinov za diagnosticiranje bolezni, analiza aminokislin za diagnosticiranje bolezni, povezave med strukturo in funkcijo v proteinskih družinah, Naddružina imunoglobulinov, DNA vezavni proteini Biološke membrane: zgradba in biološka vloga, aktivni in pasivni transport, liposomi kot prenašalci zdravil in encimov, bolezni, ki so posledica izgube fluidnosti celične membrane in okvare membranskih transportnih sistemov Metabolizem ogljikovih hidratov: glavne metabolne poti in njihova kontrola, posebne metabolne poti, sladkorna bolezen

Morphology of microorganisms. Cell structure. Structure and function of cell membranes. Cell wall of prokaryotes. Structure and functional role of subcellular organelles Microbial growth. Cell communication and signal transduction Proteins: Architecture and Biological Function, Plasma Proteins in Diagnosis of Disease, Use of Amino Acid Analysis in Diagnosis of Disease, Structure Function Relationships in Protein Families, The Immunoglobulin Superfamily, DNA-Binding Proteins Biological Membranes: Structure and biological function, Active and passive Membrane Transport, Liposomes as Carriers of Drugs and Enzymes, Diseases Due to Abnormalities of Cell Membrane Fluidity and Loss of Membrane Transport Systems Carbohydrates Methabolism: Major Metabolic Pathways and Their Control, Special Pathways,

105

Osnove molekularne genetike: DNA struktura in lastnosti, replikacija (prokarionti, eukarionti), rekombinacija DNA, DNA popravljalni, mehanizmi, mehanizem nastanka DNA mutacij, organizacija, struktura in funkcija genov, struktura genoma (rastlinski, živalski in človeški), transkripcija, translacija, regulacija genske ekspresije Osnove dedovanja, kromosomska teorija dednosti, Mendlovo dedovanje, poligensko dedovanje Rak Imunski sistem Uporaba mikroorganizmov v raziskavah in industriji Laboratorijske vaje: Karakterizacijske in separacijske metode v

mikrobiologiji Izolacija in analiza bakterijske DNA, RNA in

proteinov

Diabetes Mellitus Basic molecular genetics: DNA structure and characteristics, replication (prokaryotes, eukaryotes), recombination, repair and mutations, organization, structure and function of genes and chromosomes, genome structure (plant, animal, human) transcription (prokaryotes, eukaryotes), translation, regulation of gene expression Chromosomal basis of heredity, Mendelian inheritance, polygenic inheritance Cancer Immune system Microorganisms as tools for research and industry Laboratory work:

Characterization and separation methods in microbiology

Isolation of bacterial DNA, RNA and proteins


Madigan, T.M., Martinko, J.M., Parker, J.: Brock Biology of Microorganisms, 11th Ed., Prentice Hall, Inc., New Jersey, 2006.

Voet, Donald: Fundamentals of biochemistry: life at the molecular level, 2nd ed., J. Wiley & sons, Hoboken (New Jersey), 2006.


Nelson D. L., Cox M. M.; Lehninger Principles of Biochemistry, 4th ed, W.H. Freeman and Company, New York, 2004.

Strachan T., Read A. P.: Human Molecular genetics, Gerland Publish, Inc., New York, 3rd ed., 2004. Lodish H., Baltimore D., Berk A., Zipursky S.L., Matsudaira P., Darnell J.: Molecular Cell Biology, 6th Ed.,

Scientific American Books, Freeman and Co., New York, 2008.


Študenti bodo razumeli strukturne značilnosti in lastnosti glavnih skupin biomolekul ter njihovo vlogo v metabolizmu in ostalih bioloških procesih.

Students will understand structural characteristics of major groups of biomolecules and their role in cell metabolism and other important biological processes.



Znanje in razumevanje: Študenti bodo razumeli strukturne značilnosti in lastnosti glavnih skupin biomolekul ter njihovo vlogo v metabolizmu in ostalih bioloških procesih:

zakonitosti prenosa genetske informacije med generacijami

povezave med genotipom in fenotipom


pristopi in orodja statistične genetike

Knowledge and Understanding: Students will understand structural characteristics and properties of main groups of biomolecules, and their role in the methabolism and other biological processes:

principles of heredity and transfer of genetic information between generations

correlations genotype-phenotype Transferable/Key Skills and other attributes:

approaches and program tools for statistical genetics

106


predavanja

seminarske vaje

laboratorijske vaje

Lectures

Tutorial

Laboratory work



Assessment:

Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni izpit ustni izpit

60 40

Student has to pass successfully the following obligations: written examination oral exemination


JOSTINS, Luke, MITROVIČ, Mitja, POTOČNIK, Uroš, et al. Host-microbe interactions have shaped the genetic architecture of inflammatorybowel disease. Nature, ISSN 0028-0836, 2012, vol. 491, no. 7422, str. 119-124, doi: 10.1038/nature11582. [COBISS.SI-ID 512230968]

REPNIK, Katja, POTOČNIK, Uroš. Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene. Journal of gastroenterology, ISSN 0944-1174, 2011, vol. 46, no. 9, str. 1081-1091, doi: 10.1007/s00535-011-0426-6. [COBISS.SI-ID 15110422]

PERIN, Petra, POTOČNIK, Uroš. Polymorphisms in recent GWA identified asthma genes CA10, SGK493, and CTNNA3 are associated with disease severity and treatment response in childhood asthma. Immunogenetics, ISSN 0093-7711, 2014, vol. 66, issue 3, str. 143-151, doi: 10.1007/s00251-013-0755-0. [COBISS.SI-ID 17472790]

LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The

Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SI-

ID 16864790]

ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 0896-

8446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462]

KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja, LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of

supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102]

ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46

(3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598]

KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN

0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406]

107

Industrijski projekt


Predmet: Industrijski projekt

Course title: Industrial Project




Semester Semester


2. letni

Spring



Predavanja


Sem. vaje Tutorial




ECTS

150 5

Nosilec predmeta / Lecturer: Koordinator praks / Coordinator of industrial projects

Jeziki / Languages:

Predavanja / Lecture: Slovenski/Slovene

Vaje / Tutorial: Slovenski/Slovene


Prerequisites:

Pogojev ni. None.

Vsebina:


Študent izvaja industrijski projekt s polnim delovnim časom v (industrijski) organizaciji s področja kemije, kemijske in biokemijske tehnike ali drugih procesnih panog. Izjemoma lahko študent izvaja industrijski projekt tudi na fakulteti ali inštitutu, če je zaradi narave projekta to primerneje. Študentu sta dodeljena mentor v organizaciji in na Fakulteti za kemijo in kemijsko tehnologijo, ki je praviloma tudi mentor študentovega magistrskega dela. V času izvajanja industrijskega projekta se študent seznani z organiziranostjo, obratovanjem in poslovanjem organizacije. V okviru projekta obravnava specifični problem v organizaciji. Mentor v organizaciji vodi študenta pri izvajanju aktivnosti, ki pripeljejo do uspešnega zaključka projekta. Študent o izvajanju in rezultatih industrijskega projekta napiše poročilo.

Student works full-time in an (industrial) organization in the field of chemistry, chemical and biochemical engineering or other process related industries. The industrial project could be exceptionally carried out at the Faculty or Institute if this is required by the nature of project work. Two mentors are appointed to student: one in the organization, and the other one at the Faculty of Chemistry and Chemical Engineering, who is, as a rule, mentor of student’s Master Thesis. Student becomes acquainted with the structure, production process and management in the organization. Within the industrial project, student deals with the specific problem in the organization. Mentor in the organization leads student’s activities to the successful finish of the project. Student prepares a written report about the execution and results of the industrial project.

108


Specifično literaturo bodo študentom posredovali mentorji.



Namen industrijskega projekta je, da študent:

določen čas dela v (industrijski) organizaciji s področja kemijske in biokemijske tehnike ali druge procesne panoge

spozna organiziranost, obratovanje in poslovanje neakademske organizacije

uporabi teoretično znanje, pridobljeno med študijem, za reševanje konkretnega problema v praksi

pridobi specifične spretnosti, ki jih ne more pridobiti na fakulteti

The aim of the industrial project is to: work for the specified time period in an industrial

chemical, biochemical or other process related organization

become familiar with the structure as well as with production and management processes in non-academic organization

apply knowledge gained during the study for solving practical problem

acquire skills different from the ones taught at the Faculty




poznavanje organiziranosti, obratovanja in poslovanja neakademskih organizacij

boljše poznavanje zaposlitvenih možnosti po zaključku študija

boljše poznavanje in razumevanje nalog in odgovornosti v poklicnem okolju


to understand the structure, production and management process in non-academic organization

to increase understanding of employment options after graduation

to get a better perception of tasks and responsibilities within a professional environment

Prenesljive/ključne spretnosti in drugi atributi: prilagajanje obnašanja in ravnanja v različnih

poklicnih okoljih širši pogled na položaj organizacije v določeni

panogi in globalnem gospodarstvu (konkurenčnost)

pridobljene nove spretnosti, ki so potrebne za uspešno izvajanje in zaključek praktičnega projekta


to learn a different way of behavior, suitable for different professional environments

to obtain a better view of the position of a company compared to other companies and global economy (competition)

to obtain new skills that are necessary to successfully accomplish practical project



samostojno delo

konzultacije z mentorjem v organizaciji

priprava pisnega poročila

independent work

consultations between student and mentor in the organization

preparation of written report



Assessment:

Industrijski projekt je zaključen, če so pozitivno opravljene naslednje obveznosti:

pisno poročilo industrijskega projekta

100


written report of industrial project

Reference nosilca / Lecturer's references:

109

Magistrsko delo


Predmet: Magistrsko delo

Course title: Master Thesis




Semester Semester


2. letni

Spring



Predavanja


Sem. vaje Tutorial


Drugo* Other


ECTS

20 730 25

*Individualne kontaktne ure s profesorjem/Individual contact hours with lecturer

Nosilec predmeta / Lecturer: Vsi habilitirani visokošolski učitelji / All lecturers holding valid habilitation

Jeziki / Languages:

Predavanja / Lecture:



Prerequisites:


Priprava magistrskega dela poteka kot samostojno delo študenta na raziskovalnem projektu s področja kemijske ali biokemijske tehnike. Magistrsko delo je lahko tudi skupni raziskovalni projekt več študentov. Teme projektov za magistrska dela razpišejo mentorji v okviru raziskovalnih laboratorijev Fakultete za kemijo in kemijsko tehnologijo ali jih predlagajo študentje. Študent pridobi soglasje predvidenega mentorja, ki ga usmerja in svetuje pri izvedbi magistrskega dela. Formalni postopek priprave in zagovora magistrskega dela poteka v skladu s Pravilnikom o postopku priprave in zagovora magistrskega dela na študijskem programu 2. stopnje, Univerze v Mariboru. Predvidene aktivnosti študenta pri pripravi in zagovoru magistrskega dela so naslednje: formulacija problema

The student has to work independently on a research project concerning chemical or biochemical engineering problem. Master thesis can be a common research project of several students. The research topics are issued by the mentors in the research laboratories of the Faculty of Chemistry and Chemical Engineering or could be initiated by students. Consent of mentor is required. Mentor guides the student through the research work of Master Thesis. The formal procedure for Master Thesis preparation and defence is regulated by the “Pravilnik o postopku priprave in zagovora magistrskega dela na študijskem programu 2. stopnje” of the University of Maribor. The preparation and defence of Master Thesis usually include the following activities of student: problem formulation

110

pregled in analiza dosedanjih raziskav in relevantne literature

postavitev raziskovalnih hipotez definiranje metod dela časovni načrt izvedbe projekta praktično delo v enem od raziskovalnih

laboratorijev fakultete interpretacija in kritična presoja rezultatov priprava pisnega izdelka ustna predstavitev.

state-of-the-art in the proposed field of research and survey of the relevant literature

definition of research hypotheses definition of research methods time plan of project practical work in one of the Faculty research

laboratories interpretation and evaluation of the results written presentation of the work oral presentation of the work.


Kravanja Zdravko, Navodila za kvalitetno izvajanje magistrskega dela. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014.

http://www.fkkt.um.si/sites/default/files/Navodila%20za%20kvalitetno%20magistrsko%20delo_0.pdf

Novak Pintarič Zorka, Kravanja Zdravko, Predloga z navodili za pisanje magistrskega dela. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2015. http://www.fkkt.um.si/sites/default/files/Predloga_MAG_KT-2015.docx

Univerza v Mariboru, Pravilnik o postopku priprave in zagovora magistrskega dela na študijskem programu 2. stopnje. Obvestila UM št. XXX-5-2012, Univerza v Mariboru, 2012. http://www.um.si/univerza/dokumentni-center/akti/Strani/podrobnosti.aspx?iddok=150.


Peter Glavič: Navodila za izdelavo diplomskega dela. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2008.

Specifično literaturo bodo študentom posredovali mentorji.



Cilj je, da študent doseže: sposobnost branja in razumevanja mednarodne

literature o določenem problemu sposobnost samostojnega raziskovalno-

razvojnega dela z namenom reševanja določenega problema

sposobnost dela v interdisciplinarni skupini strokovnjakov

sposobnost predstavitve rezultatov dela strokovni javnosti v obliki pisnega poročila, predavanja, diskusije.

The student would be able to: read and understand international literature of a

specific topic work independently in a research and

development environment in order to solve specific problem

work in an interdisciplinary team of experts present the results to a professional audience by

means of a a written report, oral presentation and discussion.



poglobljeno obvladanje znanj in izrazoslovja s strokovnega področja magistrskega dela

poznavanje sistematike, metod in pristopov raziskovalno-razvojnega dela

sposobnost identifikacije, formulacije in reševanja problemov s področja kemijske in biokemijske tehnike

Prenesljive/ključne spretnosti in drugi atributi: sposobnost samostojnega raziskovalnega dela,

reševanja strokovnih problemov, kritičnega razmišljanja in razumevanja strokovne literature

sposobnost učinkovite komunikacije o strokovni problematiki


mastery of knowledge and terminology in the specific professional field of Master Thesis

knowledge of systematics, methods and approaches of research and development work,

ability of identification, formulation and solution of problems in the field of Chemical and Biochemical Engineering


ability to independently accomplish the research work, solve the professional problems, understand the literature and to think critically

ability to efficiently communicate about

111

sposobnost učinkovite predstavitve in interpretacije rezultatov dela.

problematics,

ability to efficiently present and interpret the results of work.


konzultacije in diskusije študenta z mentorjem o vsebinskem poteku dela

priprava pisnega izdelka in ustne predstavitve

consultations and discussions between student and mentor about the content and progress of the work

preparation of written report and oral presentation



Assessment:

Magistrsko delo je zaključeno, če so pozitivno opravljene naslednje obveznosti:

magistrsko delo

ustni zagovor magistrskega dela 50 50


master thesis work

master thesis oral presentation

Reference nosilca / Lecturer's references:

obrazec za opis predmeta slo/eng progami... · aparati za ekstrakcijo tekočih zmesi. hitrost...

Documents