OBAT PSIKOTROPIK =PSIKOTROPIKA =PSIKOFARMAKAAdalah obat yang bekerja secara selektif pada susunan saraf pusat (SSP)dan mempunyai efek utama terhadap aktivitas mental dan prilakun (mind and behavior altering drugs), digunakan untuk terapi gangguan psikiatrik (psychotherapeutic medication).

Orientasi pada gejala sasaran (target syndrome oriented)JENIS OBAT GEJALA SASARANAnti psikosisPsikosis Anti depresi DepresiAnti mania ManiaAnti anxietas AnxietasAnti insomnia InsomniaAnti obsesif kompulsifObsesif kompulsifAnti panikPanik

WHO-REVISED LIST OF ESSENTIAL DRUGS 1994Section 24. Psychotherapeutic DrugsObat Psikotropik24.1.Drugs used in psychotic Anti - Psikoticdisordes24.2.Drugs used in moodAnti-depresidisorders Anti-mania 24.3. Drugs used in obsessive Anti-anxietas and generalised anxietyAnti-insomnia disorders 24.4. Drugs used in

Butir-butir yang harus selalu di-ingat dalam penggunaan klinis obat psikotripika Sesuai dengan situasi dan kondisi individual (tailored)Penyesuaian secara bertahap (stepwise)Pantau terus menerus (monitoring)Terencana dan terprogram (rational management)

I.OBAT-OBATA ANTI PSIKOSISNEUROLEPTICS, MAJOR TRANQUILLIZERS ANTARICTICS, ANTIPSYCHOTICS, ANTIPSYCHOTIC DRUGS, NEUROLEPTIKA

II. OBAT ANTI-PSIKOSIS TIPICAL (TYPICAL ANTI PSYCHOTICS)Phenotiazine * rantai Aliphatic: chlorpromazine (largactil)* rantai Piperazine: perphenazine (stelazine) trifluoperazine (antensol)*rantai Piperidine: thioridazine (melleril)2.Butyrophenone : haloperidol (haldol, serenace,dll)Diphenyl-butyl -: pimozide (Orap) piperidine

III.Obat anti-psikosis atipikal (atypical anti psychotics)Benzamide : Sulpiride (Dogmatil)Dibenzodiazepine : Clonzapine (Clozaril) Olanzapine (Zyprexal) Quetiapine (Seroquel) Zatepine (Lodopin)Benzisoxazole : irsperidon (Risperdal) Aripiprazole (Abilify)

OBAT ANTI DEPRESI 1.THYMOLEPTICS, PSYCHIC ENERGIZERS, ANTI DEPTRESSANTS, ANTIDEPRESAN

1. Tricyclic Compound : Amitriptyline (Amitriptyline) IMIPRAMINE (Tofrnil) Clomipramine (Anafranil) Tianeptine (Stablon)2. Tetracyclic Compound : Maprotinile (Ludionil) Mianseri (Tolvon) Amoxapine (Asendin)3. Mono-Amine-OxydaseInhibitor (MAO)-Reversible: Moclobemide (Aurorix)Selective Serotonin Re-uptake Inhibitors (SSRI) : Sertraline (Zoloft) Paroxetine (Seroxat) Fluvoxamine (Luvox) Fluoxetine (Prozac) Citalopram (Cipram) Duloxetine (Cymbalta)5. Atypical Antidepresants : Trazodone (Trazone) Mirtazapine (Remoron) Venlafaxine ( Efexor)

OBAT ANTI MANIAMOOD MODULATORS, MOOD STABILIZERS, ANTIMANICS Mania Akut : Haloperidol (haldol, serenace, dll) Carbamazepine (Tegretol) ; Vaproic (Depakene); Diivalproex (Depakote)Profilaksis Mania : Lithium Carbonate (Frimania)

OBAT ANTI ANXIETAS Psycholeptics, minor trnquillizers anxiolytics, antianxiety drugs, ansiolitika

1.BenzodiazepineDiazepam(Valium,Stesolit,dll) Chlordiazepoxide (Cetabrium, dll)Bromazepam (Lexotan)Lorazepam (Ativan, Renaquil, Merlopan)Alprazolam(Xanax, Alqanax, Calmlet,dll)Clobazam(Frisium, dll) 2.Non-BenzodiazepineBuspirone(Buspar, Tran-Q, Xiety)Sulpiride (Dogmatil-50)Hydroxyzine (Iterax)

OBAT ANTI INSOMNIA HYPNOTICS, SOMNIFACIENT, HIPNOTIKA BENZODIAZEPINE Nitrazepam ( Dumolid ) Flurazepam( Dalmadorm ) Estazolam ( Esilgan )

NON-BENZODIAZEPINEZolpidem( 0Stilnox,Zolmia )

1.Obat Anti-Obsesif Kompulsif Trisiklik Clompramine (Anafranil)Obat anti Obsesif KompulsifSetraline (Zolaft)Paroxetine (Seroxat)Fluvoxamine(Luvox)Fluoxetine(Prozac)Citalopram(Cipram)

OBAT ANTI-PANIKDRUGS USED IN PANIC DISORDER

Obat anti panik TRISIKLIKImipramine (Tofrani)Clomipramine (Anafrani)Obat anti-panik BENZODIAZEPINEAlprazolam (Xanaz, Alqanax,Calmlet, dll)Obat anti-panik RIMA (Reversible Inhibitors of Monoamine oxydase-A)Moclobemide (Aurorix)Obat anti-panik SSRISertralne (Zoloft)Paroxetine(Seroxat)Fluvoxetine(Luvox)Fluoxetine(Prazac)Citalopram(Cipram)