obat imunosupresan kel 1 ppt.pptx

7/25/2019 Obat imunosupresan kel 1 ppt.pptx

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OBATIMUNOSUPRESANDISUSUN OLEH:

Kelompok 1

ABDUL NASIR (2015001183 AP!IA SERUNI (20150012"2 DIMPOS #ULTOM (2015001203

ANITA $HOERUNNISA (20150011%3 DE&I 'ERIANTI (20150012)2 !ATHIMAH A**AHRA (2015001282


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PENDAHULUAN

Imunosupresan

kelompok o+,- .,/ /,k,//-k me/ek,/ 4epo/ m/ epe4-pe/6e,7 pe/ol,k,/ -4,/p,l,/

me/,-, pe/.,k- ,-om/ ,/me/6e,7 7emol 47e ,//eo/,-9 Se+,,/ ,4 kelompok

+e4,- -o-ok ,/ /,k,/e+,, ,/-k,/ke4

Imm/op4e,/ me4p,k,/ ;,--, -em

m/ e/,/ =,l,/ /-e4,k +e4+,, --k ,4 -em -e4e+-9


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IMUNITAS

IMUNITAS SPIMUNITAS

NONSPESI!IK


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Im/-, pe?kMemlk k,4,k-e4, k7 ,/-,4, l,/ kem,mp,//., /-k+e4e,k e6,4, pe?k e/,/ ,/-e/ -e4-e/-@ kem,mp,/mem+e,k,/ ,/-e/ ,/ e/,/ ,/-e/ e/4 (/o/el-e47,,p el @ ,/ kem,mp,/ /-k +e4e,k le+7 6ep,- ,/le+7 eee/ -e47,,p ,/-e/ .,/ ,7 ke/,l e+elm/.,9Repo/ m/ pe?k / -e44 ,4 , -em m/ .,- m/-,elle4 ,/ m/-, 7mo4,l9 Im/-, ele4 mel+,-k,/ ellmpo- T e,/k,/ m/-, 7mo4,l mel+,-k,/ lmpo- B ,/el pl,m, .,/ +e4/ memp4ok ,/-+o9

Im/-, /o/pe?k9

Me4p,k,/ mek,/me pe4-,7,/,/ -e4ep,/ .,/ melp

?k +e4p, ke-7,/ kl- ,/ mko,@ kompo/e/ +ok

,,m l,m+/ lo;m komplome/- @ ,/ kompo

/o/pe?k epe4- /e-4o?l ,/ m,k4o,9 Ne-4o?l

mel,kk,/ ,o-o -e47,,p +e/, ,/ ,/

+e4+,, me,-o4 /-k me/,4k el


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PENGOBATAN

,9 Repo/ m/ p4me4 le+7 m,7 ke/,lk,/ ,/ +,//k,/ e/,/ 4epo/ m/ ek/e49 T,7,p ,,l 4epo/

me/6,kp: pe/ol,7,/ ,/-e/ ole7 AP$ /-e lmok/ p4o,/ e4e/, el


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TERDAPAT EMPAT KELOMPOK OBAT IMUNOSUPRDIGUNAKAN DI KLINIK :

1. KORTIKOSTEROID

Ko4-ko-e4o (lkoko4-ko /,k,/ e+,, o+,- -/,l ,-, ,l,m kom+/,m/op4e,/ l,/ /-k me/6e,7 4e,k pe/ol,k,/ -4,/pl,/-, ,/ /-k mpe/.,k- ,-om/9 P4e/o/ ,/ p4e/olo/ me4p,k,/ lkoko4-ko .,/ p,l/

/,k,/9Mean!sme er"a : lkoko4-ko ,p,- me/4/k,/ =ml,7 lmo- e6,4-e4-,m, ,l,m o +e,49 Eek / .,/ +e4l,// +e+e4,p, =,m , -e4=,4e-4+ lmo- S- -e4+,4 me//=kk,/ +,7, ko4-ko-e4o me/7,m+,- pel lmo- T m/-, elle4 ,/ ekp4e e/ .,/ me/.,/ +e4+,, -ok/ (IIL


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&. PENGHAMBAT KALSINE

a.S!$ospor!n

Mean!sme Ker"a : me/7,m+,- k,l/e4/9 D,l,m -opl,m, lmo- T ($D

+e4k,-,/ e/,/ klo?l/9 Ik,-,/ / el,/=-/., me/7,m+,- / k,l/e4/9 K,,,l,7 e/;m o,-,e epe/e/- k,lm ,/ meme,/ pe4,/,/ k/6 ,l,m e(,k->, p4o-e/ 4el,-o4 -ool Se-el,7 me/,l,m eoo4l, kem,/ m-4,/lok, ke ,l,m /kle /-k me/,k-k,/ e/ .,/ +e4-,// =,,/-e -ok/ -e4-,m, IL


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(. Taro$!mus

Mean!sme Ker"a : T,k4olm ,/ klopo4/ memlk -4k-4 km, +e4+e,

+eke4=, e/,/ mek,/me .,/ ,m, .,- me/7,m+,- k,l/e4/9 Pe4+ee/,/ klopo4/ ,l,m -opl,m, lmo- T ($D -,k4olm +e4k,-,/ e/,+// p4o-e/ (!KBP9 Ik,-,/ / el,/=-/., me/7,m+,- / k,l/e4/9 K,,,l,7 e/;m o,-,e epe/e/- k,lm ,/ meme,/ pe4,/,/ k/6eoo4l, (,k->, p4o-e/ 4el,-o4 -ool .,- N!AT6 (Nuclear factor of accell9 Se-el,7 me/,l,m eoo4l, N!AT6 / me/,l,m -4,/lok, ke ,l,m/-k me/,k-k,/ e/ .,/ +e4-,// =,,+ ,l,m /-e -ok/ -e4-,,/ +e4+,, p4o-oo/koe/ epe4- 6


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). SITOTOKSIa. A*%!opr!n

Mean!sme Ker"a : ,;,-op4/ ,,l,7 me-,+ol- olo/,/ p4/ .,/ me

p4ek4o4 "


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(. M!o'eno$a% Mo'e%!$

Mean!sme Ker"a : mkoe/ol,- moe-l me4p,k, e4>,- em,,m mkoe/ol,-9 A,m mkoe/ol,- ,,l,7 pe/7,m+,- k,-mo/oo,- e74oe/,e e/;m pe/-/ p,, /-e e /o>oLmo- B ,/ T -e4,/-/ p,, e/;m / /-k /-e pe7/, o+,- / me/7,m+,- ,k->, lmo- B ,/ T9 Mkome/ek,/ p4ole4, lmo- ,/ pem+e/-k,/ ,/-+o ole7 el B/ =, me/7,m+,- pe/ol,k,/ -4,/pl,/-, /=,l mempe4ppe/e4m,,/ -4,/pl,/-, ,/ me/4,/ pe/ol,k,/ ,k- ,/ k4

E'e Samp!n# :eek ,mp/ melp- m,l m/-,7 ,4e ,k-,/ melop4e9In%eras! : pe//,,/ mkoe/ol,- moe-l +e4,m, ,/-,,me/,// Al OH ,/ m,/em ,k,/ me/4/k,/ ,+o4p9


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+. S!$o'os'am!,E'e Samp!n# : pem+e4,/ o +e,4 k,-k,/ e/,/ eek ,mp/7emo4,k k,4o-ok-, ,/ p,/-ope/, +e4,-9Mean!sme Ker"a : kloo,m me4p,k,/ ,lkl,-o4 olo/,/ m-,4

.,/ me/.e+,+k,/ ,lkl, p,, DNA e7/, me/7,m+,- /-e ,/ /Sel B ,/ T ,m,


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. ANTIBODI

a. An%!(o,! po$!$ona$ :.ATG /An%!%0mo+%e2

Mean!sme Ker"a : Me4p,k,/ ,/-+o polklo/,l .,/ +e4k,-,/ p,, +e4+,, molekl pe4mk,,/ lmo- T ,/ mkel, HLA kel, I ,/ II9

E'e Samp!n# :Eek ,mp/ .,/ 4el,- e4/ serum si,/ /e4-9 Eek ,mp/ l,/ em,m me/l leko

-4om+o-ope/, ,/ 4,m kl-9

In,!as! :Me/o+,- 4e,k pe/ol,k,/ -4,/pl,/-, /=,l =,/-/ ,-,l,/9 ', /,k,/ e+,, p4o?l,k e+elm -4,/pl,/-,


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IGI3 /Imuno#$o(u$!n I32.

Mean!sme Ker"a : Mek,/me ke4=,/., +e4,,4k,/ pe/4,/,/ =ml,7 el T 7elpe4 pe//

=ml,7 el T p4eo4 ,/ me/4,/ p4om/olo+l/9

In,!as! :

Pe/o+,-,/ respiratory sinotitial virus sitomegalovaricella zoster human herpes virus 3 7ep,-- B 4,/ -e-,/


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a. An%!(o,! mono$ona$ :.An%! 4D)

In,!as! :D/,k,/ p,, -4,/pl,/-, /=,l 7,- ,/ =,/-/9 Sel,/ -/,k,/ /-k me/4,/ =ml,7 el T e+elm -4,/pmm -l,/9Mean!sme er"a :Be4k,-,/ e/,/ molekl $D3 .,- kompo/e/ 4eep-o4 el

+e4pe4,/ p,, ,e pe/e/,l,/ ,/-e/9E'e samp!n# :Cytokine release syndrome .,/ ,p,- -e4=, p,, o ,+e4>,4, ml, ,4 u like syndrome ,mp, .ok +e4,-me/,/6,m /.,,9


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Tras%u*uma(

In,!as! :D/,k,/ p,, k,/ke4 p,.,4, me-,-,-k p,, p,e/ ekp4e HER


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ANALISIS RESEIm/op4e


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RS A%ma"aa

'l9 Pl- R,., No9 2',k,4-, U-,4,

Telp (021 ""0"12)

',k,4-, 1 3 201"Ale4 O+,- : TIDAK A

A : 9999999999999999999999999999999Dok-e4 : 49 ,7. Sp9 PD

R $ell6ep- 500 m NoS 2 1 p6

R Ne4o+o/ 500 mI&

S 1 1R Me-7.l p4e/olo/

S


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Sk4// Am/-4,-Ke$en#apan

Resep

Ke%eran#an

N,m, Dok-e4 49 ,7. Sp9 PD

SIP 4 Kol-e4,m/ &,k/

Pem(er!an O(a%

Se+,k/., +e4k,/ p,, ,,- pe4- koo/9

P,, p,e/ pe/e4m, -4,/pl,/-, /=,l .,/ -,+

+e4k,/ +e4,m, m,k,/,/ +l, pe4l9


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Ne4o+o/ 5000Pa(r!

Mer+

In,ones!aGo$on#an Be(a

Ben%u Se,!aan T,+le- HNA5%a( Rp 292

Kompos!s! &- B1 100 m &- B" 100 m &- B12 5000 m6

In,!as!

Pe/o+,-,/ >-,m/ B1 B" ,/ B12 epe4- p,, +e

pol/e4- /e4- pe4e4 ,/ /e4,l,9 Mem+,/-

me/6e,7 komplk, /e4op,- pe4e4 ,+e-k9

Dos!s Se7,4 1 -,+le- e-el,7 m,k,/

In%eras! O(a% Le>oop,

Pem(er!an O(a% Se+,k/., +e4k,/ +e4,m, m,k,/,/

Me-7.l


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Me-7.lP4e/olo/Pa(r! He6p0arm 7aa Go$on#an OKeua%an m 1" m HNA5%a( R

Kompos!s! Me-7.l P4e/olo/e

In,!as!

Kel,/,/ e/ok4/ pe/. ,-om/ pe/. 4em,-k .,/ mem+e4 4

-e4,p ko4-ko-e4o pe/. kol,e/ pe/. kl- ,le4 /,m, pe

/,, kel,/,/ 7em,-olo /eopl,m, eem, / ,l pe/6e4/,,,4 ml-ple kle4o me//- -+e4klo, /4om, /e4o-k

Kon%ra In,!as! I/ek =,m4 -emk 7e4pe mplek DM m/, >,4el, o

Per0a%!an

K0usus

Pe//,,/ =,/k, p,/=,/ ,/ o -/ >,k/, TB 4o

ke6e/e4/,/ pko /?e/ /=,l lk pep-k 7,ml ,/

E'e Samp!n#

#/ elek-4ol- ,/ 6,4,/ -+7 (4e-e/ N, ,/ 6,4,/ / pe/.e

me-,+olme k,4+o74,- lem,7 o-o- / pe/6e4/,,/ ke4/,- +e

o-eopo4o pe//k,-,/ -ek,/,/ /-4,k4,/,l / kl me/-4pe4-m+7,/ p,, ,/,k k,-,4,k l,kom, ,/,?l,k

Dos!s

A,l: Se7,4


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Pe47-/,/ DoNama O(a% Dos!s

La*!m

/50ar!2

Dos!s

16

Dos!s 10r

M!o'eno$a%

mo'e%!$

/4e$$+ep%2

2 1 500 m 1

Neuro(!on 8999 1 -,+ 1 -,+ 1 -,+

Me%0$

pre,n!so$on

m#


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Pe47-/,/H,4,Nama I%em 7m$

%a(

HNA 5%a( Per0!%un#an

4e$$+ep%

/M!o'eno$a%

mo'e%!$2

15

-,+

Rp

219%3%0"

15 21%3%90"

191 1925 1000

Neuro(!on 8999 15

-,+Rp 292%0%2

15 22%09%2

191 1925 1000

Me%0$pre,n!so$

on m#30

-,+Rp 800

30 800 191

1925 1000

P$as%! $!p3 p6 Rp 100 3 100

P$as%! pu%!0

$o#o1 p6 Rp 200 1 200

To%a$


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PENIAPANRESEP


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Pe/.,p,/ Reep

Am+l o+,- e=ml,7 4eep .,/ +-7k,/:

Cellcept 500 mg ta ! "5 ta

Neuroion 5000 ta ! "5 ta

#ethyl $rednisolon % mg ta! 30 ta

M,kk,/ m,/


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Pem+e4,/E-ke-

APOTEK ;ARMASI PAN4ASILA

'l9 S4e/e/ S,,7 ',,k,4,Telp9 )8" )2)

No: 01 Tl: 3005201"

T/9 T= M,/ L

2 e7,4 1 -,+Se+elm m,k,/

$ell6ep- 500m

e: M,4 Q18

APOTEK ;ARMASI PAN4ASILA'l9 S4e/e/ S,,7 ',,k,4,

Telp9 )8" )2)No: 01 Tl: 3005201"

T/9 T= M,/ L

1 e7,4 1 -,+15 me/- e+elm m,k,/

Ne4o+o/5000

e: '/ Q18

APOTEK ;ARMASI PAN4ASILA'l9 S4e/e/ S,,7 ',,k,4,

Telp9 )8" )2)No: 01 Tl: 3005201"

T/9 T= M,/ L

2 e7,4 -,+ (p,


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Pe/.e4,7,/ ,/ Pem+e4,/I/o4m, $ell6ep- : O+,- / me4p,k,/ o+,- /-k me/6e,7 pe/ol,k,/

o4,/ .,/ ,k,/ -4,/pl,/-,9 Dm/m 2 e7,4 1 -,+le-

e+elm m,k,/9 U,7,k,/ m/m p, ,/ m,l,m +e4el,/ 12=,m m,l/., =,m 8 p, ,/ =,m 8 m,l,m9

Ne4o+o/ 5000 : Me4p,k,/ pleme/ +e4 >-,m/9 Dm/m1 e7,4 1 -,+le- 15 me/- e+elm m,k,/9 Se+,k/., m/mp, 7,4 ,,4 +,,/ -e4,, e,4 e+elm +e4,k-?-,9

Me-7.l P4e/olo/ m : O+,- .,/ mem+,/- $ell6ep- ,,4o4,/ .,/ l,m, ,p,- le+7 m,7 me/e4m, o4,/ .,/ ,k,/

-4,/pl,/-,9 Dm/m 2 e7,4 15 me/- e+elm m,k,/p, ,/ m,k,/ ,/9 Dm/m ek,l -,+le-9

Bl, pe4l /,k,/ pe//,- ,-, p,,/ ,l,4m 7,/p7o/e,,4 -,k -e4lp, m/m o+,-

I-4,7,- 6kp ,/ +,/.,k m/m ,,4 -,k kek4,/,/ 6,4,/9


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DRU# RELATEDPROBLEM

RESEP IMUNOSUPRES

l 7


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K$as!


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Pe/.e+,+M,,l,7

K$as!


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SIMPULANIm/op4e,/ ,,l,7 kelompok o+,- .,/ /,k,/ /-k m

4epo/ m/ epe4- pe/6e,7 pe/ol,k,/ -4,/p,l,/ me/,-, ,-om/ ,/ me/6e,7 7emol 47e ,/ /eo/,-9 Im/o/,k,/ /-k -, /k, -,m, .,- -4,/pl,/,-, o4,/ ,-om/ ,/ pe/6e,7,/ 7emol R7e p,, /eo/,-9P4/p mm pe//,,/ m/op4e,/ /-kme/6,p, 7,.,/ op-m,l ,,l,7 e+,, +e4k-:19 Repo/ m/ p4me4 le+7 m,7 ke/,lk,/ ,/

+,//k,/ e/,/ 4epo/ m/ ek/e4929 O+,- m/op4e,/ mem+e4k,/ eek .,/ +e4+e, -e47,,p

.,/ +e4+e,939 Pe/7,m+,-,/ 4epo/ m/ le+7 +e47,l +l, o+,- m/o

+e4k,/ e+elm p,p,4,/ -e47,,p ,/-e/9


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D,-,4 p-,k,

A/o/m9 20009 nformatorium )at Nasional ndonesia ()N*+ D4e

Pe/,,,/ O+,- ,/ M,k,/,/ Dep,4-eme/ Kee7,-,/ Rep+lk I/o/e Dep,4-eme/ !,4m,kolo ,/ Te4,pe-k !K UI9 200)9 ,armakologi dan

',k,4-,: B,,/ !,4m,kolo !K UI9

El/ 9 S9 kk9 20089 .) ,armakoterapi9 ',k,4-, : PT9 IS!I9

See-m,/ S e- ,l9 200%9 #artindale 3"-7 The Complete /rug P7,4m,6e-6,l P4e9 Lo/o/9

Me6,pe9 20119 D4 I/-e4,6-o/ $7e6ke49 (7--p:94ee4e/6e9me6,pe96om4


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obat imunosupresan kel 1 ppt.pptx

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