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Page 1: NTHB flipbook

TRANSCRIPTION

STARTS NOW

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RNA Polymerase

1. RNA polymerase binds to an unwound DNA and unwinds it. Creates initiation bubble. 2. RNA polymerase bonds to the promoter region of the DNA.

Coding region

Prompter Region

Termination Sequence

Start codon is AUGIn promoter region.

Nucleus

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A T G C T G G A T T G G C A A G C G A T T G G C A A G G C T

T A C G A C C T A A C C G T T C G C T A A C C G T T C A A G

RNA Polymerase

RNA goes through Nuclear pore

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A T G C T G G A T T G G C A A G C G A T T G G C A A G G C T

T A C G A C C T A A C C G T T C G C T A A C C G T T C A A G

RNA Polymerase

A U G C U G G A U U G G C A A G C G A U U G G C A A G U U C

RNA goes through Nuclear pore

3. RNA polymerase binds to DNA, and creates RNA.

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A T G C T G G A T T G G C A A G C G A T T G G C A A G G C T

T A C G A C C T A A C C G T T C G C T A A C C G T T C A A G

RNA Polymerase

A U G C U G G A U U G G C A A G C G A U U G G C A A G U U C

RNA goes through Nuclear pore

4. RNA hits stop codon and stops making RNA.

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A T G C T G G A T T G G C A A G C G A T T G G C A A G G C T

T A C G A C C T A A C C G T T C G C T A A C C G T T C A A G

RNA Polymerase

A U G C U G G A U U G G C A A G C G A U U G G C A A G U U C

RNA goes through Nuclear pore

5.RNA exits nucleus and enters cytoplasm.

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TRANSLATION

STARTS NOW

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1. mRNA forms to ribosome

Cytoplasm

mRNARibosome

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2. mRNA binds to ribosome and reads 1st codon (A-U-G)

A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

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3. tRNA brings anti-codon that is complementary.

A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

tRNAAnti-Codon

U A C

Amino Acid

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A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

4a. Amino Acid attaches and starts to form peptide chain with peptide bonds

U A C G A C C U A A C C G U U C G C U A A

Peptide Bond

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A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

4b. The tRNA and anti-codon falls off after a new tRNA comes.

U A C G A C C U A A C C G U U C G C U A A

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A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

After the last tRNA falls off, the Ribosome falls off with it.

U A C G A C C U A A C C G U U C G C U A A

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A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

After the last tRNA falls off, the Ribosome falls off with it.

U A C G A C C U A A C C G U U C G C U A A

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A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

After the last tRNA falls off, the Ribosome falls off with it.

U A C G A C C U A A C C G U U C G C U A A

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A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

After the last tRNA falls off, the Ribosome falls off with it.

U A C G A C C U A A C C G U U C G C U A A

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A U G C U G G A U U G G C A A G C G A U U G G C A A G G U C

U A C G A C C U A A C C G U U C G C U A A

Tyr Asp Leu Thr Val Arg STOP

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5. The amino acids form proteins.

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SummaryFirst, the RNA polymerase binds to an unwound DNA and unwinds it.

This creates the initiation bubble. Then, the polymerase binds to the promoter region of the DNA strand. Next, the polymerase reads the DNA and creates the mRNA. The RNA hits the stop codon, and stops making the mRNA. The mRNA leaves the nucleus and enters the cytoplasm.

Then we move on to translation. First, the rRNA forms to the ribosome. Then, the mRNA binds with the rRNA and reads the first codon in the strand. The tRNA brings in the anticodon, which is the opposite, or complementary, to the mRNA strand. The amino acids attach and start to form the polypeptide chain. Finally, the ribosome hits the stop codon on the mRNA and they form the proteins needed to survive.