nhgri gwa catalog hcorrada/cmsc858b/lectures/lect16/gwas_2010_4.pdf · o aids progression o alcohol...

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NHGRI GWA Catalog www.genome.gov/GWAStudies Published Genome-Wide Associations through 12/2010, 1212 published GWA at p< 5x10 -8 for 210 traits

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Page 1: NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O AIDS progression O Alcohol dependence Alopecia areata O Alzheimer disease O Amyloid A levels O Amyotrophic

NHGRI GWA Catalogwww.genome.gov/GWAStudies

Published Genome-Wide Associations through 12/2010, 1212 published GWA at p<5x10-8 for 210 traits

Page 2: NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O AIDS progression O Alcohol dependence Alopecia areata O Alzheimer disease O Amyloid A levels O Amyotrophic

CMSC858B: Computational systems biology and functional ...users.umiacs.umd.edu/~hcorrada/CMSC858B/lectures/lect1/CMSC858P_Lecture1.pdfCMSC858B: Computational systems biology and functional

Take a read: mRNA abundance - University Of Marylandhcorrada/CMSC858B/lectures/lect12/RNAseqI.pdf · mRNA abundance estimation with RNAseq Hector Corrada Bravo CMSC858B Spring 2012

bwt and fm indexusers.umiacs.umd.edu/~hcorrada/CMSC423/lectures/CMSC423... · 2015. 12. 10. · Burrows-Wheeler Transform Characters of the BWT are sorted by their right-context This

Second-Generation Sequencing Introduction to second-generation sequencing …users.umiacs.umd.edu/~hcorrada/CMSC858B/lectures/lect22... · 2012-02-27 · ionTorrent 21 Oxford Nanopore

Stanford University · O o o o o o o O o o o o o o o o o o o o o O o o o O o o o o O O o O o o . o o o o o O o o o o o o O o o o O o n o O o o o o o o o o o O o o o O o

PATTERN’RECOGNITION’’ AND’MACHINE’LEARNING’cbcb.umd.edu/~hcorrada/PML/pdf/lectures/prml-slides-8.pdf · prml-slides-8.ppt Author: Hector Corrada Bravo Created Date: 11/26/2012

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Ensemble(Methods( - users.umiacs.umd.eduusers.umiacs.umd.edu/~hcorrada/PML/pdf/lectures/EnsembleMethods.pdfgot wrong, you study more. Then you take the exam again and repeat this process

Gene expression analysis with R and Bioconductorusers.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21... · Gene expression analysis with R and Bioconductor: from measurements to annotated

NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010...O LP (a) levels O LpPLA(2) activity and mass Lung cancer Magnesium levels Major mood disorders Malaria O Male pattern

Chapter(03(–Linear(Regression( - UMIACSusers.umiacs.umd.edu/~hcorrada/IntroDataSci/lectures/Regression.pdf · Chapter(03(–Linear(Regression(Slides(by(ZiaKhan(Simple(Linear(Regression(0

PATTERN’RECOGNITION’’ AND’MACHINE’LEARNING’users.umiacs.umd.edu/~hcorrada/PML/pdf/lectures/prml-slides-8.pdf · The(SumPProductAlgorithm((8)(To(compute(local(marginals:(•

Lecture 7: Smoothingusers.umiacs.umd.edu/~hcorrada/PracticalML/pdf/lectures/smoothing.pdf · Lecture 7: Smoothing Rafael A. Irizarry and Hector Corrada Bravo March, 2010 Kernel Methods

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Gene Expression Analysis with R and Bioconductor: …legacydirs.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21...Gene Expression Analysis with R and Bioconductor: from measurements to

… · O O o o O o o o o O o o o o o O 0 o o o o o o o o O o o o o o O o o o o . o O o O o o o o O o O o o O o o o o o O O O o O O o o O o o o O o o o o

Cluster Analysis of Genomic Data - University Of Marylandcbcb.umd.edu/~hcorrada/CFG/readings/Solutions_ch13.pdf · Cluster Analysis of Genomic Data ... we generalize the output of

CMSC702: Computational systems biology and functional …users.umiacs.umd.edu/~hcorrada/CFG/lectures/lect1_Intro/CMSC702_Lecture1.pdfD. Minden7, Stephen E. Sallan1,3,4, Eric S. Lander5,

Analysis of Diﬀerential Gene Expression Studieshcorrada/CMSC858B/readings/Solutions_ch14.pdf · a case study of the estrogen data in Section 14.3.1. 14.2 Diﬀerential expression

Ensemble(Methods( - CBCBcbcb.umd.edu/~hcorrada/PracticalML/pdf/lectures/EnsembleMethods.… · Ensemble(Methods(Adapted(from(slides(by(Todd ... models(are(linearly(combined,(we

Examining the relative inﬂuence of familial, genetic, and ...hcorrada/CMSC858B/readings/bdes.pdf · risk models Héctor Corrada Bravoa,1, ... Sudha K. Iyengarc, and Grace Wahbad,1

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Transcription factors Transcription Factor Analysis - …hcorrada/CMSC858B/lectures/lect23_transfac/lect...Transcription Factor Analysis 5 The challenges: 1.Complexity: hundreds of

NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O LP (a) levels O LpPLA(2) activity and mass Lung cancer Magnesium levels Major mood disorders Malaria O Male

A,) \.l~'~ vw \\ dt~-\-0S'--\-,U0 (r,~0)The" href="https://vdocuments.mx/0-uj-hcorradacfglectureslect7differentialexpressionii-loj1-r-vrj.html">~0( UJ - CBCBcbcb.umd.edu/~hcorrada/CFG/lectures/lect7_DifferentialExpressionII/... · \L{(_oJ1 r-vrJ~ ~"J~ ~ \:)(\ ~0(./'(bJ ~J::: UJ II> A,) \.l~'~ vw \\ dt~-\-0S'--\-,U0 (r,~0)The

A statistical framework for modeling gene expression …hcorrada/CMSC858B/readings/svmIntegrate.pdf · A statistical framework for modeling gene expression using chromatin features

Gene Expression Analysis with R and Bioconductor: …cbcb.umd.edu/~hcorrada/CFG/lectures/lect21_bioc/bioconductor.pdf · Gene Expression Analysis with R and Bioconductor: from measurements

q-value - CBCBcbcb.umd.edu/~hcorrada/CFG/lectures/student_presentations/qvalue.pdf · set q-value cutoff at .05, and be sure that only 5% of the significant genes found are likely

Gene Expression Analysis with R and Bioconductor: from ...users.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21_bioc/bioconductor.pdf · postulated that gene expression profiles of the

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A super quick introduction to molecular biology and genomicsusers.umiacs.umd.edu/~hcorrada/CMSC423/lectures/... · A super quick introduction to molecular biology and genomics Héctor

Cluster Analysis of Genomic Datausers.umiacs.umd.edu/~hcorrada/CFG/readings/Solutions_ch...clustering algorithm, consider the output if the algorithm were applied to the data generating

LWF-Fläche Chironico...o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o

RNAseq: isoform expression quantiﬁcation and transcript …users.umiacs.umd.edu/~hcorrada/CMSC858B/lectures/lect13/... · 2012. 3. 5. · transcript assembly Slides courtesy from