new toxicology database
DESCRIPTION
New Toxicology Database. Tracie Phillips, Ph.D. Toxicology Division Texas Commission on Environmental Quality Advanced Air Permitting Seminar-October 2014. Objectives. Introduce New Database Demo of Database Prototype Testing the Database. NEW. A new beginning. - PowerPoint PPT PresentationTRANSCRIPT
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New Toxicology Database
Tracie Phillips, Ph.D.Toxicology DivisionTexas Commission on Environmental QualityAdvanced Air Permitting Seminar-October 2014
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Objectives
• Introduce New Database• Demo of Database Prototype• Testing the Database
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THE NEW TOXICOLOGY DATABASE
A new beginning
NEW
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What is the new database?
Housed within the TAMIS database
One stop shop:• ESL List• AMCV List• Supporting
documents
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Why are we changing?
• Reduce errors• Proper database structure• More information/detail• Dynamic
Manual Spreadsheets
1000’s of Chemicals
Errors & Frustration
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What will be different?
1. No more “Published List” spreadsheets
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What will be different?
2. Information will be dynamic
Database
Updates
New Info
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What will be different?
3. ESL requests
• Consult the database 1st
• No verification for existing values
Database = Real Time
• At least a 2-week turnaround:• Each value documented
• Should be received early in the permitting process
New ESL Request
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What will be different?
4. All associated documentation will be linked:
• DSDs• Fact sheets• Public comments• Interim documentation
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What will be different?
5. Screening level reports
ReportsToxicology Reports
ESLEffects Screening Levels
SummaryValues used in
Permitting Only
DetailAll Values (Health &
Welfare)
AMCVAir Monitoring
Comparison Values
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What will be different?
6. More detail will be available:• Each value will be dated
Substance CASNo. Phase
Short-term ESL-
Health (ug/m3)
Short-term ESL-
Health (ppb)
Date Derived Status
Interim Source
Used for Air
Permitting Review
Short-term ESL-
Odor (ug/m3)
Short-term ESL -
Odor (ppb)
Date Derived Status
Odor Source
Used for Air
Permitting Review
antimony 7440-36-0 PM10 5 -- 10/1/2003 InterimNIOSH,
TLV, OSHA YES -- -- -- -- -- --benzene 71-43-2 -- 170 54 3/1/2011 Final -- YES 8700 2700 10/17/2007 Final -- --
cyclohexene 110-83-8 -- 600 180 6/28/2010 Interim
NIOSH, TLV, OSHA, FRG-MAK -- 10000 3000 6/28/2010 Interim Amoore YES
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What will be different?
7. Source codes
Odor Interim
Long-term Short-term
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What will be different?
8. List will be searchable by:
• Date• Substance:
• CAS#• Identified synonyms
• Substance type:• Alcohols• Surrogates
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What will be different?
9. Use of surrogates:• Promotes consistency
Children
Parent Chemical A
Chemical X
Chemical Z
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What will be different?
10. Identified synonyms
Styrene
Phenyl- ethylene
Vinyl benzene
Styrene Monomer
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What is the timeline?
(4) Full Production – No More Published List:Date TBD
(3) Transition
& Beta Testing: Date TBD
(2) External
User Testing:Date TBD
(1) Internal
User Testing:Date TBD
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PROTOTYPE DEMOTime for a conceptual demonstration
**For example purposes only, the following is not a true representation of the final product
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TAMIS Welcome Screen
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Login Screen
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Report Selection Screen – Wizard Mode
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Date Selection Screen
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Report Parameter Criteria Screen
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File Delimiter Selection Screen
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Report Generation Screen
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Report Output in Excel
Substance CASNo. Phase
Short-term ESL
(ug/m3)
Short-term ESL
(ppb)Date
Derived StatusChemical
BasisInterim Source Odor Source
Long-term ESL
(ug/m3)
Long-term ESL
(ppb)Date
Derived StatusChemical
BasisInterim Source
DSD derived date DSD Fact Sheet
Public comments Appendices
benzene 71-43-2 170 54 3/1/2011 Final Health 4.5 1.4 2/1/2011 Final Health 2/1/2011 http:/… http:/… http:/… http:/…
benzene polymer 71-43-2 MUST MEET
NAAQS
benzene resin 71-43-2 CONTACT
TOXICOLOGY
ethylene 71-85-1 1400 1200 4/15/2008 Final Odor PEL 34 30 4/15/2008 Final Health 4/15/2008 http:/… http:/… http:/… http:/…hydrogen fluoride
and soluble inorganic
fluorides, for permit reviews in
agricultural areas with cattle,
as HF 7664-39-3 3 3.7 (24 h) 9/15/2003 Final animal 0.75 0.91 9/15/2003 Final animal 9/15/2003 http:/… http:/… http:/… http:/…hydrogen fluoride
and soluble inorganic
fluorides, for permit reviews in
agricultural areas, as HF 7664-39-3 3 3.7 (24 h) 1/23/2013 Final vegetation 0.6 0.75 1/23/2013 Final vegetation 1/23/2013 http:/… http:/… http:/… http:/…
hydrogen fluoride and soluble
inorganic fluorides, as HF 7664-39-3 PM10 18 22 5/23/2007 Final Health 8.7 11 5/23/2007 Final Health 5/23/2007 http:/… http:/… http:/… http:/…
glycols, polyethylene, mono-(1,1,3,3-
tetramethylbutylphenyl) ether 9036-19-5 PM10 50 -- 1/23/2013 Interim Health NESCAUM 5 -- 1/23/2013 Interim Health 1/23/2013 http:/… http:/… http:/… http:/…
glycols, polyethylene, mono-(1,1,3,3-
tetramethylbutylphenyl) ether 9036-19-5 VAPOR 600 -- 5/23/2007 Interim Health Leonardos 60 -- 5/23/2007 Interim Health TLV-TD 5/23/2007
glycols, polypropylene,
2,3-epoxypropyl ether (DER 736 Epxoy Resin) 9072-62-2 PM10 50 -- 1/23/2013 Interim Odor Nader 5 -- 1/23/2013 Interim Health 1/23/2013
glycols, polypropylene,
2,3-epoxypropyl ether (DER 736 Epxoy Resin) 9072-62-2 VAPOR 1000 -- 5/23/2007 Interim Odor Leonardos 100 -- 5/23/2007 Interim Health 5/23/2007
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TESTING THE DATABASETesters Wanted!
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External Testing
If you would like to participate, send an email to:
• Tracie Phillips: [email protected]
-or-• Toxicology Division: [email protected]
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Tracie Phillips, [email protected]
To improve is to change; to be perfect is to change often.
-Winston Churchill