new projects at embl approved in 2007 -...

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New Projects at EMBL Approved in 2007 (for the period 15.11.06-15.11.07) Protein Crystallography PX-06-382 Structure of plasminogen activator inhibitor-I (PAI-I) inhibiting antibody fragments (Fabs) Rabijns Leuven PX-06-383 Structural studies on E. coli Serine HydroxyMethyl Transferase (SHMT) mutants Ilari Rome PX-06-384 UDP-sugar-pyrophosphorylase Ficner Göttingen PX-06-385 Poly-A-specific Ribonuclease PARN Ficner Göttingen PX-06-386 Structure of interferon Lambda and its receptor Nissen Aarhus PX-06-387 Structure of malonate decarboxylase (AMDase) Sträter Leipzig PX-06-388 Finding new trypsin inhibitors Heine Marburg PX-06-389 Structure of Ecto-Nucleosidetriphosphate diphosphohydrolases (ENTPDase) Sträter Leipzig PX-06-390 Structural biology of bacterial disaccharide phosphorylases Savvides Ghent PX-06-391 tehA Schmitt Düsseldorf PX-06-392 Structure of sugar binding hydrolase enzymes DECLERCQ Louvain-la- Neuve PX-06-393 Crystallographic structure analyses of the nuclear import complexes ImpBeta/Imp7/H1 and ImpBeta/SPN1 Ficner Göttingen PX-06-394 Neutral protease from Bacillus polymyxa Wyns Brussel PX-06-395 L-carbamoylase from Sinorhizobium meliloti Wyns Brussel PX-06-396 Structure solution of Early B-Cell Factor (EBF), a transcription factor that contains a novel DNA binding domain bound to DNA Schulz Freiburg PX-06-397 Structure determination of Pex3, a human membrane protein involved in peroxisome biogenesis Schulz Freiburg PX-06-398 Structure of 2,6-Dihydroxypyridine 3- Hydroxylase from arthrobacter nicotinovorans Schulz Freiburg PX-06-399 Structure determination of a complex consisting of PEX19 and the membrane protein PEX3, two human proteins involved in peroxisome biogenesis Schulz Freiburg PX-06-400 Palmitylation of BET3 Heinemann Berlin PX-06-401 Reducion of metal centres by X-rays: Cu,Zn SOD Djinovic- Carugo Vienna PX-06-402 Reducion of metal centres by X-rays: Ni SOD Djinovic- Carugo Vienna PX-06-403 Reducion of metal centres by X-rays: SW myoglobin Djinovic- Carugo Vienna PX-06-404 Carbonic anhydrase:CO2 : does the pH in crystal change with deposited X-ray dose Djinovic- Carugo Vienna 653

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Page 1: New Projects at EMBL Approved in 2007 - DESYhasyweb.desy.de/science/annual_reports/2007_report/part2/...New Projects at EMBL Approved in 2007 (for the period 15.11.06-15.11.07) Protein

New Projects at EMBL Approved in 2007 (for the period 15.11.06-15.11.07)

Protein Crystallography

PX-06-382 Structure of plasminogen activator inhibitor-I

(PAI-I) inhibiting antibody fragments (Fabs)

Rabijns Leuven

PX-06-383 Structural studies on E. coli Serine HydroxyMethyl Transferase (SHMT) mutants

Ilari Rome

PX-06-384 UDP-sugar-pyrophosphorylase Ficner Göttingen

PX-06-385 Poly-A-specific Ribonuclease PARN Ficner Göttingen

PX-06-386 Structure of interferon Lambda and its receptor Nissen Aarhus

PX-06-387 Structure of malonate decarboxylase (AMDase) Sträter Leipzig

PX-06-388 Finding new trypsin inhibitors Heine Marburg

PX-06-389 Structure of Ecto-Nucleosidetriphosphate

diphosphohydrolases (ENTPDase)

Sträter Leipzig

PX-06-390 Structural biology of bacterial disaccharide phosphorylases

Savvides Ghent

PX-06-391 tehA Schmitt Düsseldorf

PX-06-392 Structure of sugar binding hydrolase enzymes DECLERCQ Louvain-la-

Neuve

PX-06-393 Crystallographic structure analyses of the nuclear import complexes ImpBeta/Imp7/H1 and

ImpBeta/SPN1

Ficner Göttingen

PX-06-394 Neutral protease from Bacillus polymyxa Wyns Brussel

PX-06-395 L-carbamoylase from Sinorhizobium meliloti Wyns Brussel

PX-06-396 Structure solution of Early B-Cell Factor (EBF), a transcription factor that contains a novel DNA

binding domain bound to DNA

Schulz Freiburg

PX-06-397 Structure determination of Pex3, a human

membrane protein involved in peroxisome

biogenesis

Schulz Freiburg

PX-06-398 Structure of 2,6-Dihydroxypyridine 3-Hydroxylase from arthrobacter nicotinovorans

Schulz Freiburg

PX-06-399 Structure determination of a complex consisting

of PEX19 and the membrane protein PEX3, two human proteins involved in peroxisome

biogenesis

Schulz Freiburg

PX-06-400 Palmitylation of BET3 Heinemann Berlin

PX-06-401 Reducion of metal centres by X-rays: Cu,Zn SOD Djinovic-

Carugo

Vienna

PX-06-402 Reducion of metal centres by X-rays: Ni SOD Djinovic-

Carugo

Vienna

PX-06-403 Reducion of metal centres by X-rays: SW myoglobin

Djinovic-Carugo

Vienna

PX-06-404 Carbonic anhydrase:CO2 : does the pH in crystal

change with deposited X-ray dose

Djinovic-

Carugo

Vienna

653

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PX-06-405 Phytase of klebsiella Heinemann Berlin

PX-06-406 Crystal structure of SnogD Schneider Stockholm

PX-06-407 Glutaconyl-CoA decarboxylase from Clostridium symbiosum

Essen Marburg

PX-06-408 Structure of 14-3-3 protein lambda Schomburg Cologne

PX-06-409 Structure of Pyrococcus furiosus MoaB Schomburg Cologne

PX-06-410 Cofactor Analysis of Arabidopsis thaliana Cnx1

G-Domain

Schomburg Cologne

PX-06-411 complex of chitinase B with inhibitory peptides Hoehne Berlin

PX-06-412 INH data collection PXInternal Hamburg

PX-06-413 Putative Heavy atom ATPase chaperone Nissen Aarhus

PX-06-414 Complexes of c-terminal tails of vps10 receptors and cytoplasmic factors

Nissen Aarhus

PX-06-415 Structure determination of the RACK1 protein Nissen Aarhus

PX-06-416 Biotin ligase Wyns Brussels

PX-06-417 Bacterial ferritin Wyns Brussels

PX-06-418 Acyl coA synthase FadD13 Wyns Brussels

PX-06-419 Transamidosome Nissen Aarhus

PX-06-420 Actin*Riz complex Heinz Braunschweig

PX-07-001 Non-receptor tyrosine kinase Fes catalitic domain Rosano Genova

PX-07-002 PPI, a new protease inhibitor from papaya Wyns Brussels

PX-07-003 Bacterial TA modules Wyns Brussels

PX-07-004 Bacterial fimbrial adhesins Wyns Brussels

PX-07-005 Crystal structure of IDC epimerase Schneider Stockholm

PX-07-006 Crystal structure of AknOx Schneider Stockholm

PX-07-007 Dehydropyrimidine dehydrogenase Schneider Stockholm

PX-07-008 Crystal structure of RdmE Schneider Stockholm

PX-07-009 Phospholipase A2 Schneider Stockholm

PX-07-010 Structural studies of plant pathogenesis-related

proteins

Jaskolski Poznan

PX-07-011 Structural biology of plant-bacterium symbiosis Jaskolski Poznan

PX-07-012 Protease inhibitors from pathogenic protozoa Jaskolski Poznan

PX-07-013 VHH antibody fragments from camels Wyns Brussels

PX-07-014 Mechanism of disulphide formation in Escherichia coli Ribonuclease 1

Wyns Brussels

PX-07-014 Mechanism of disulphide formation in

Escherichia coli Ribonuclease 1

Wyns Brussels

PX-07-015 T. cruzi Glucokinase Wyns Brussels

PX-07-016 Microbial nucleoside hydrolases Wyns Brussels

PX-07-017 IPDC/PPDC from Azospirillum brasilense Wyns Brussels

PX-07-018 Structure of enzymatic antioxidants Declerq Louvain-la-Neuve

PX-07-019 Complexes and mutants of apoferritin Declerq Louvain-la-

654

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Neuve

PX-07-020 BAS Schneider Stockholm

PX-07-021 MDH Schneider Stockholm

PX-07-022 SnogD Schneider Stockholm

PX-07-023 Directed evolution of enzymes Declerq Louvain-la-Neuve

PX-07-024 Microgravity grown crystals Declerq Louvain-la-

Neuve

PX-07-025 Structural Genomics Studies of S. mutans proteins

Su Beijing

PX-07-026 Structural anf functional studies on proteins

related to B. subtilis histidine degradation

Su Beijing

PX-07-027 Structural and functional studies of important human proteins

Su Beijing

PX-07-028 UDP-sugar-pyrophosphorylase Ficner Göttingen

PX-07-029 Class 2 histone deacetylase homologue (HDAH) Ficner Göttingen

PX-07-030 Crystal structure of mutants of Salicylate 1,2-

Dioxygenase from Pseudaminobacter

salicylatoxidans and of the complex with

substrates

Briganti Florence

PX-07-031 Crystallographic study of the substrate specificity of 4-chlorocatechol 1,2-dioxygenase from

Rhodococcus opacus 1CP

Briganti Florence

PX-07-032 Structural Characterization of intermediates in the catalytic pathway of Laccase from Trametes

trogii

Briganti Florence

PX-07-033 Crystallographic structure of Laccase from Trametes trogii complexed with natural mediator

Briganti Florence

PX-07-034 Alpha-1,3-Galactosyltransferase: Catalytic

Mechanism and Inhibitor Design

Acharya Bath

PX-07-035 Interferon-Inducible Protein 10 (IP-10):

Glycosaminoglycan and Receptor Interactions

Acharya Bath

PX-07-036 Streptococcus suis Dpr Papageorgiou Turku

PX-07-037 Glutathione transferase Papageorgiou Turku

PX-07-038 tehA Schmitt Düsseldorf

PX-07-039 The molecular determinats of OpuAC, the SBP of

the osmo-regulated ABC-transporter OpuA from B. subtilis

Schmitt Düsseldorf

PX-07-040 The nisin exporter complex of L. lactis Schmitt Düsseldorf

PX-07-041 An ABC-transporter specific protease domain Schmitt Düsseldorf

PX-07-042 ChoX, the SBP of an ectoine specific ABC-

importer

Schmitt Düsseldorf

PX-07-043 Na,K ATPase Nissen Aarhus

PX-07-044 Inhibitor complexes of SR Ca2+-ATPase Nissen Aarhus

PX-07-045 Structure of interferon Lambda and its receptor Nissen Aarhus

655

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PX-07-046 H+-ATPase from A. thaliana Nissen Aarhus

PX-07-047 Yeast Rrp6p Nissen Aarhus

PX-07-048 Structure of the Vps10p domain of human Sortilin

Nissen Aarhus

PX-07-049 IgA proteases Nissen Aarhus

PX-07-050 Derivatised cyclodextrins and inclusion

complexes of cyclodextrins

Mavridis Aghia Paraskevi

PX-07-051 Complexes of cyclodextrins with DNA and RNA Mavridis Aghia Paraskevi

PX-07-052 Structure of Ferredoxins Mavridis Aghia Paraskevi

PX-07-053 Depolymerase Papageorgiou Turku

PX-07-054 Structural investigation of PACSINs, adaptor proteins involved in endocytosis and actin

rearrangement

Wittmann Göttingen

PX-07-055 AOC I and II - two novel allene oxide cyclases Ficner Göttingen

PX-07-056 Novel Uracil-specific DNA repair enzyme Ficner Göttingen

PX-07-057 tRNA modifying enzyme ThiI from Thermotoga

maritima

Ficner Göttingen

PX-07-058 Carbonic anhydrase IX Brynda Prague

PX-07-059 Archaeal ExoIII homologue Ficner Göttingen

PX-07-060 Laccase from Melanocarpus albomyces Rouvinen Joensuu

PX-07-061 Tyrosinase from Trichoderma reesei Rouvinen Joensuu

PX-07-062 UsnRNA 5'-cap Dimethyltransferase TGS1 Ficner Göttingen

PX-07-063 Spliceosomal helicase Prp22 - Truncation H20 Ficner Göttingen

PX-07-064 Spliceosomal helicase Prp22 - Truncation H13 Ficner Göttingen

PX-07-065 Spliceosomal helicase Prp22 - Truncation H7 Ficner Göttingen

PX-07-066 NrfHA complex of W. succinogenes Einsle Göttingen

PX-07-067 Diheme cytochrome DHC2 Einsle Göttingen

PX-07-068 Acetylene hydratase of P. acetylenicus Einsle Göttingen

PX-07-069 Ammonium Transporter Einsle Göttingen

PX-07-070 Xanthomonas RoxA Einsle Göttingen

PX-07-071 Aquifex aeolicus Ferredoxin Einsle Göttingen

PX-07-072 Cytochrome c perxoidases Einsle Göttingen

PX-07-073 Aplysia amino acid oxidase Einsle Göttingen

PX-07-074 Nitrogenase Einsle Göttingen

PX-07-075 Structure-function studies of wild type and

mutant bacterial and human thiolases

Wierenga Oulu

PX-07-076 Structural studies of fatty acyl CoA thioesterases Wierenga Oulu

PX-07-077 protein engineering: towards a new substrate specificity of a monomeric variant of TIM

Wierenga Oulu

PX-07-078 Structural studies of the enzymes involved in

protein folding in ER

Wierenga Oulu

PX-07-079 Novel trypsin from crab Betzel Hamburg

PX-07-080 Important RNA's in biotechnology Betzel Hamburg

656

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PX-07-081 Glutathione S-transferases from helminths Betzel Hamburg

PX-07-082 Student course (Test data collection for different

protein crystals)

Betzel Hamburg

PX-07-083 Different complexes of ML1 with native

inhibitors

Betzel Hamburg

PX-07-084 New plant inhibitors for urease, acetylcholin esterase and glycosidase

Betzel Hamburg

PX-07-085 Crystallographic structure analyses of the nuclear

import complexes ImpBeta/Imp7/H1 and ImpBeta/SPN1

Ficner Göttingen

PX-07-086 Myosin-myosin receptor Niessing München

PX-07-087 Myosin-myosin receptor co-complex / different

crystal form

Niessing München

PX-07-088 RNA-binding by the novel type of RNA-binding

protein She2p

Niessing München

PX-07-089 Poly-A-specific Ribonuclease PARN Ficner Gttiöngen

PX-07-090 Spliceosomal helicase Prp28 Ficner Göttingen

PX-07-091 Crystal Structure Determination of Cyclodextrin

Inclusion Compounds with Substanses of Agricultural Interest

Hountas Athens

PX-07-092 Structural studies of a bacterial bifunctional

glutathione synthetase (gshF)

Savvides Ghent

PX-07-093 Structural studies of Old Yellow Enzyme from S.

Oneidensis at ultra-high resolution

Savvides Ghent

PX-07-094 Structural biology of bacterial disaccharide

phosphorylases

Savvides Ghent

PX-07-095 Structural studies of adenylate kinases from the malaria parasite

Savvides Ghent

PX-07-096 Structural studies of the membrane-associated

agglutination protein, AggA, from S. Oneidensis

Savvides Ghent

PX-07-097 Structural studies of paracoccus C551, a di-heme

cytochrome.

Savvides Ghent

PX-07-098 Structural studies of hematopoietic cytokine-

receptor interactions

Savvides Ghent

PX-07-099 cytochromes P450 Podobnik Ljubljana

PX-07-100 Structural studies on phosphodiesterase from Mtb Podobnik Ljubljana

PX-07-101 Structure-function analysis of Fatty acyl synthases and polyketide synthases from

Mycobacterium tuberculosis

Rajan Hyderabad

PX-07-102 Peptide nucleic acid complexes Sheldrick Göttingen

PX-07-103 Tri- Peptidyl Peptidase Sheldrick Göttingen

PX-07-104 Beamline validation test crystal protocol Sheldrick Göttingen

PX-07-105 Antibiotics and their complexes Sheldrick Göttingen

PX-07-106 Fes kinase FCH domain Rosano Genova

PX-07-107 Structural basis of antibodies affinity maturation Rosano Genova

657

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PX-07-108 Structure of hydrolase enzymes Wouters Namur

PX-07-109 Human DNA Polymerase beta in complex with

resveratrol analogues

Rosano Genova

PX-07-110 GAL4_CRD1 Brynda Prague

PX-07-111 Carbonic anhydrase IX Brynda Prague

PX-07-112 Crystal structure of Pa5349 - a rubredoxin

reductase from Pseudomonas aeruginosa

Heinz Braunschweig

PX-07-113 PrfA / DNA Complex : PrfA, transcriptional regulator of virulence factor of Listeria

monocytogenes in complex with its cognate DNA

Heinz Braunschweig

PX-07-114 Strukturanalyse von SidA Heinz Braunschweig

PX-07-115 Modulation of Binding Strength in the complex of Internalin from L.monocytogenes and human

E-Cadherin

Heinz Braunschweig

PX-07-116 Structure of SdsA1(Pa0740) - an alkyl sulfatase from Pseudomonas aeruginosa

Heinz Braunschweig

PX-07-117 Crystal structure of the YopO/Actin complex Heinz Braunschweig

PX-07-118 Autolysin, a cell-wall modulating virulence factor

from Listeria monocytogenese

Heinz Braunschweig

PX-07-119 Functional and mutational analysis of the radical SAM enzyme HemN from E. coli

Heinz Braunschweig

PX-07-120 Structure of IPP isomerase Wouters Namur

PX-07-121 Crystal structure of pyruvamide activated

pyruvate decarboxylase from Kluyveromyces lactis

Koenig Halle/Saale

PX-07-122 InlB-Met complex Heinz Braunschweig

PX-07-123 Determination of the crystal structure of oxalyl

coenzyme A decarboxylase from Mycobacterium

tuberculosis and Escherichia coli in the presence

of subs

Koenig Halle/Saale

PX-07-124 Structure base of dephosphorylation catalyzed by

human protein phosphatase PP2C-beta

Essen Marburg

PX-07-125 Structural analysis of cyanobacterial

phytochromes

Essen Marburg

PX-07-126 Structural analysis of enzymes from the nicotinate degradation pathway of Eubacterium

barkeri

Essen Marburg

PX-07-127 Structural characterization of domains and bidomains from non-ribosomal peptide

synthetases (NRPS)

Essen Marburg

PX-07-128 Structural analysis of the plant cryptochrome cry3 Essen Marburg

PX-07-129 Structural studies of human and Chlamydomonas reinhardtii prolyl 4-hydroxylases

Wierenga Oulu

PX-07-130 Structural studies on domains of human collagen

prolyl 4-hydroxylase

Wierenga Oulu

658

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PX-07-131 atomic resolution crystallography of TIM-transition state complexes

Wierenga Oulu

PX-07-132 Structure investigation of L1-rRNA recognition Nikonov Pushchino,

Moscow region

PX-07-133 Structure investigation of archaeal initiation factor aIF2

Nikonov Pushchino, Moscow region

PX-07-134 High-resolution structures of L-methionine

gamma-lyase in complex with substrates and inhibitors

Nikonov Pushchino,

Moscow region

PX-07-135 Study of L-methionine gamma-lyase working

mechanism

Nikonov Pushchino,

Moscow region

PX-07-136 Crystal structure of mutant forms of Hfq protein Nikonov Pushchino, Moscow region

PX-07-138 Polyneuridine aldehyde esterase enzyme-ligand

complex

Stoeckigt Mainz

PX-07-139 Catalytic Mechanism and rational Modulation of Strictosidine Synthase

Stoeckigt Mainz

PX-07-140 Structure of raucaffricine glucosidase in complex

with substrate and inhibitors

Stoeckigt Mainz

PX-07-141 Strictosidine Glucosidase enzyme-substrate complex

Stoeckigt Mainz

PX-07-142 Vinorine synthase enzyme-substrate complex Stoeckigt Mainz

PX-07-143 Perakin reductase enzyme-substrate complex Stoeckigt Mainz

PX-07-144 SS_Sm1-RNA complex Suck Heidelberg

PX-07-145 SS_Sm2-RNA complex Suck Heidelberg

PX-07-146 Pop2-RNA complex Suck Heidelberg

PX-07-147 AF_Sm2-RNA complex Suck Heidelberg

PX-07-148 Structure of a polysaccharide deacetylase from

Bacillus cereus

Kokkinidis Heraklion

PX-07-149 DNA methyltransferase BseCI (apoenzyme /

protein-DNA complex)

Kokkinidis Heraklion

PX-07-150 Structure of berberine-bridge-forming-enzyme

(BBE) from Eschscholzia californica

Kratky Graz

PX-07-151 Crystal structure of D-threonine aldolase from Alcaligenes xylosoxidans

Kratky Graz

PX-07-152 Structure and mechanism of HNL from Adenia

racemosa

Kratky Graz

PX-07-153 Glutamate mutase from Clostridium cochlearium: mutants, variants with synthetically modified

cofactors, and enzyme-substrate complexes

Kratky Graz

PX-07-154 Complexes of the Fc domain of IgG with ligands Bujacz Lodz

PX-07-155 Neutral protease from Bacillus polymyxa Wyns Brussel

PX-07-156 Hydrophobin HFBII Rouvinen Joensuu

PX-07-157 Crystal structure of phosphoketolase Wille Frankfurt/M.

PX-07-158 Substrate binding in the active center and in an Wille Frankfurt/M.

659

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ancillary binding site of pyruvate oxidase

PX-07-159 Exploration of the incorporation of a new

antisense oligonucleotide on

d(CGCGAA*TTCGCG)

VanMeervelt Leuven

(Heverlee)

PX-07-160 Exploration of the conformation of a non-selfcomplementary modified

d(GCGT*GCG/CGCACGC) oligonucleotide

VanMeervelt Leuven (Heverlee)

PX-07-161 Structural investigation of the CeNA:RNA hybrid ce(GCGTAGCG):r(CGCAUCGC)

VanMeervelt Leuven (Heverlee)

PX-07-162 Hydrophobin HFBI Rouvinen Joensuu

PX-07-163 apo-vldl-2 Rouvinen Joensuu

PX-07-164 Rubredoxin from Pyrococcus abyssi Ladenstein Huddinge

PX-07-165 ESDM Rouvinen Joensuu

PX-07-166 Protein - ligand recognition Sevcik Bratislava

PX-07-167 Crystal structure of the S-layer protein

rSbsC(447-1099)

Kratky Graz

PX-07-168 Structure of the major mite allergen Der p 5 Kratky Graz

PX-07-169 Structure determination of timothy grass pollen

allergen Phl p 3

Kratky Graz

PX-07-170 Determination of the crystal structure of

tyrosinase from mushrooms

Krebs Muenster

PX-07-171 Determination of the crystal structure of aureusidin synthase from coreopsis lanceolata

Krebs Muenster

PX-07-172 Structure solution of the poreforming membrane

protein Porb from Corynebacterium glutamicum

Schulz Freiburg

PX-07-173 Structure solution of TAM from Chondromyces crocatus

Schulz Freiburg

PX-07-174 Structure solution of Early B-Cell Factor (EBF), a

transcription factor that contains a novel DNA binding domain bound to DNA

Schulz Freiburg

PX-07-175 Structure determination of Pex3, a human

membrane protein involved in peroxisome biogenesis

Schulz Freiburg

PX-07-176 Structure of 2,6-Dihydroxypyridine 3-

Hydroxylase from arthrobacter nicotinovorans

Schulz Freiburg

PX-07-177 Structure determination of a complex consisting

of PEX19 and the membrane protein PEX3, two

human proteins involved in peroxisome biogenesis

Schulz Freiburg

PX-07-178

Novel architectures of REs and their interaction with DNA

Grazulis

Vilnius

PX-07-179 NCCGGN recognising restriction endonucleases Grazulis Vilnius

PX-07-180 Interactions of restriction-modification systems

with modified targets and cofactors

Grazulis Vilnius

660

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PX-07-181 RE domain organization Grazulis Vilnius

PX-07-182 Glycogen phosphorylase is employed as a

molecular target for the discovery of new potent

hypoglycaemic agents

Oikonomako

s

Athens

PX-07-183 Structure-assisted inhibitor design on Ribonucleases

Oikonomakos

Athens

PX-07-184 Structural characterisation of human pancreatic

glucokinase in complex with potent activators

Oikonomako

s

Athens

PX-07-185 Structure determination of the Alocasia Macrorhiza lectin (AML)

Oikonomakos

Athens

PX-07-186 Interaction of drug design targets with small

molecules

Grazulis Vilnius

PX-07-187 Structures of bacterial Type III Secretion System proteins

Kokkinidis Heraklion

PX-07-188 Crystal structure analysis of a picornaviral

protease

Curry London

PX-07-189 Structural Analysis of Ligand Binding to Mammalian Serum Albumins and albumin-heme

complexes

Curry London

PX-07-190 Crystallographic analysis of La-RNA interactions Curry London

PX-07-191 Structural studies on antimicrobial RNases Boix Bellaterra

PX-07-192 Structure determination of the EstA from Burgholderia gladioli

Kratky Graz

PX-07-193 3D structure of the K5 lyase from E.coli Kratky Graz

PX-07-194 PTP-BL catalytic domain Scheidig Homburg

PX-07-195 Protein Engineering of RedOx proteins Scheidig Homburg

PX-07-196 Testosterone binding FAB fragment mutants Rouvinen Joensuu

PX-07-197 Hevein-binding FAB-fragment of IgE antibody Rouvinen Joensuu

PX-07-198 M1 Fab-fragment Rouvinen Joensuu

PX-07-199 Beta-lactoglobulin binding Fab-fragment of IgE

antibody

Rouvinen Joensuu

PX-07-200 Diketone cleaving enzyme DKE2 from Burkholderia xenovorans

Kratky Graz

PX-07-201 T3 Fab fragment Rouvinen Joensuu

PX-07-202 Protein structure determination of the SOX gene

cluster

Scheidig Homburg

PX-07-203 Determination of substrat-enzyme complexes of dioxygenase from Acinetobacter johnsonii

Kratky Graz

PX-07-204 Structure of the membrane bound light harvesting

complex of Amphidinium carterae

Hofmann Bochum

PX-07-205 Structural study of glycosyl hydrolases Sevcik Bratislava 45

PX-07-206 Influence of mutations on crystallization, protein stability and flexibility

Sevcik Bratislava 45

PX-07-207 The soluble Peridinin Chlorophyll a Protein from

Amphidinium carterae

Hofmann Bochum

661

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PX-07-208 Refolded Peridinin Chlorophyll a Proteins from Dinoflagellates

Hofmann Bochum

PX-07-209 The crystal structure of the extracellular lipase

LipA from serratia marcescens

Baumann Bern

PX-07-210 crystal structure of the membrane-standing metalloprotease FtsH with different nucleotides

and inhibitors

Baumann Bern

PX-07-211 Mutants of the bacterial reaction center from Rhodobacter sphaeroides

Hofmann Bochum

PX-07-212 Mutants of bacteriorhodopsin Hofmann Bochum

PX-07-213 Alleneoxide cyclase from Arabidopsis thaliana Hofmann Bochum

PX-07-214 Membrane bound Alleneoxide Synthase from

Arabidopsis thaliana

Hofmann Bochum

PX-07-215 Structure of the membrane bound CPx-ATPase

CopB from Sulfolobus solfataricus, soluble

domains and holoprotein

Hofmann Bochum

PX-07-216 Rubisco aus Thermosynechoccus elongatus Hofmann Bochum

PX-07-217 Pex15P aus Saccharomyces cerevisiae Hofmann Bochum

PX-07-218 Structure of Ecto-Nucleosidetriphosphate diphosphohydrolase (ENTPDase)

Straeter Leipzig

PX-07-219 Structure of malonate decarboxylase (AMDase) Straeter Leipzig

PX-07-220 Structure and Function of PDE4A Straeter Leipzig

PX-07-221 The crystal structure of hypethermophilic nitrilase

from archaea

Rypniewski Poznan

PX-07-222 Unravelling trinucleotide repeat disorders in humans

Rypniewski Poznan

PX-07-223 The structure of phosphofructokinase from O.

cuniculus

Rypniewski Poznan

PX-07-224 Structures of Engineered Variants of the ColE1 Repressor of Primer Protein (Rop)

Kokkinidis Heraklion

PX-07-225 Structural study of a novel flavodoxin-like

protein WrbA from Escherichia coli

Kuta-

Smatanova

Nove Hrady

PX-07-226 Complexes of tethering factors at the cis-Golgi involved in vesicle transport and membrane

fusion.

Heinemann Berlin

PX-07-227 Complexes of tethering factors at the cis-Golgi

involved in vesicle transport and membrane

fusion.

Heinemann Berlin

PX-07-228 Methenyltetrahydrofolate synthetase/substrat/inhibitor complex

Heinemann Berlin

PX-07-229 Human p97/VCP/Ataxin-3 complex Heinemann Berlin

PX-07-230 Mycobacterium tuberculosis Antigen 85 secreted

enzyme

Heinemann Berlin

PX-07-231 KorB/KorA/ATPase IncC2 complex structure and

Y-BOX1, Y-BOX2 DNA binding proteins

Heinemann Berlin

662

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PX-07-232 Pontin/reptin complex Heinemann Berlin

PX-07-233 Nuclear receptor PPARgamma heterocomplexes Heinemann Berlin

PX-07-234 Capside binding domain P22TSP with ILE-zipper Heinemann Berlin

PX-07-235 Cocrystallization of SF6-/HK620TSP and O-Antigen oligosaccharides

Heinemann Berlin

PX-07-236 Targets of calmodulin in the nervous system Kursula Oulu

PX-07-237 MOBP, a key autoantigen in multiple sclerosis Kursula Oulu

PX-07-238 Adaptor/scaffolding proteins Gajhede Copenhagen

PX-07-239 Ionotropic glutamate receptors Gajhede Copenhagen

PX-07-240 Cell adhesion molecules Gajhede Copenhagen

PX-07-241 Functional domains of the myelin-associated

glycoprotein

Kursula Oulu

PX-07-242 Capsid binding domains from Sf6- and HK620TSP

Heinemann Berlin

PX-07-243 A comparative structural analysis of human

profilin isoforms

Kursula Oulu

PX-07-244 Fatty acid 2-hydroxylase in the synthesis of

myelin lipids

Kursula Oulu

PX-07-245 Cathepsin D Brynda Prague

PX-07-246 Stability matrices in P22TSP Heinemann Berlin

PX-07-247 SCP-2L (sterol carrier protein-2 like domain of

MFE-2)

Glumoff Oulu

PX-07-248 Multifunctional enzyme type 2 (mammalian) Glumoff Oulu

PX-07-249 Multifunctional enzyme type 2 (yeast) Glumoff Oulu

PX-07-250 Structure of a sucrose:fructan-6-fructosyltransferase from Pachysandra terminalis

Rabijns Leuven

PX-07-251 The structure of a cell wall invertase from

Arabidopsis thaliana (in complex with ligands)

Rabijns Leuven

PX-07-252 Structure of a taumatin-like xylanase inhibitor Rabijns Leuven

PX-07-253 Structure determination of an arabinofuranosidase

of glycoside hydrolase family 43

Rabijns Leuven

PX-07-254 Structure of an inactivated xylanase in complex

with different (arabino)xylan ligands

Rabijns Leuven

PX-07-255 The structure of plasminogen activator inhibitor-1

in complex with a Fab

Rabijns Leuven

PX-07-256 Structure of plasminogen activator inhibitor-I

(PAI-I) inhibiting antibody fragments (Fabs)

Rabijns Leuven

PX-07-257 Poplar Thioredoxin PtTrxh4 Aubry Nancy

PX-07-258 Zn-binding Thioredoxin 2 from E. coli Aubry Nancy

PX-07-259 Allosteric coupling in revTetR Muller Erlangen

PX-07-260 Crystal strcuture of a de novo designed heterodimeric TetR protein

Muller Erlangen

PX-07-261 AF-Hjc Suck Heidelberg

PX-07-262 CCE1 from Candida glabrata Suck Heidelberg

663

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PX-07-263 Structure determination of yeast Hcr1 in complex with its interaction partners Tif32 and Prt1

Ficner Göttingen

PX-07-264 Tet Repressor in complex with different

tetracyclines

Hinrichs Greifswald

PX-07-265 Finding new lead structures for HIV-Protease Heine Marburg

PX-07-266 De novo structure determination of Prephenate Dehydratase (PDT)

Heine Marburg

PX-07-267 finding new thrombin inhibitors Heine Marburg

PX-07-268 Catalysis and domain motion of K. lactis

hexokinase

Straeter Leipzig

PX-07-269 Structure determination of aldose reductase mutant inhibitor complexes

Heine Marburg

PX-07-270 X-ray structures of substrate-enzyme complexes

in bacterial transketolase

Tittmann Halle/Saale

PX-07-271 Structural characterization of the molecular interactions of protein kinase CK2 and its

subunits

Niefind Cologne

PX-07-272 Structures of shikimate dehydrogenase

isoenzymes from Corynebacterium glutamicum

Niefind Cologne

PX-07-273 Structural studies on activated pyruvate oxidase

from E.coli in complex with quinone 0

Tittmann Halle/Saale

PX-07-274 CCR4-NOT complex Suck Heidelberg

PX-07-275 Sirv2-DNA complex Suck Heidelberg

PX-07-276 Resuscitation promoting factors Berisio Naples

PX-07-277 Ribosome inactivating proteins Berisio Naples

PX-07-278 Structural studies of myosin J Fedorov Hannover

PX-07-279 Structural studies of UDP-glucose complexed with inhibitors

Fedorov Hannover

PX-07-280 UDP-glucose pyrophosphorylase (UGP) in

complex with Glucose-1-phosphate and UTP-

gamma-S

Fedorov Hannover

PX-07-281 UDP-glucose pyrophosphorylase (UGP) in

complex with Glucose-1-phosphate and UMP.V2O6

Fedorov Hannover

PX-07-282 Structural studies of myosin 1C motor in apo-

form and in complex with substrates and substrate

analogs

Fedorov Hannover

PX-07-283 Structural studies of UDP-glucose

pyrophosphorylase mutants

Fedorov Hannover

PX-07-284 Structural studies of myosins in complex with isoform-specific inhibitors

Fedorov Hannover

PX-07-285 Structural studies of plant myosins (class XI). Fedorov Hannover

PX-07-286 Structure and function of NADH oxidase (NOX)

from Lactobacillus brevis

Niefind Cologne

PX-07-287 Structure determination of Single-Stranded DNA- Fedorov Hannover

664

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binding protein complexes.

PX-07-288 Structural studies of myosin 1B in native and

mutant forms in complex with non-hydrolysable

ATP analogs.

Fedorov Hannover

PX-07-289 Structural studies of myosin J fused with 2R alpha-actinin repeats complexed with AMP,

dimer of meta-vanadate and blebbistatin

Fedorov Hannover

PX-07-290 Structural studies of myosin mutants. Fedorov Hannover

PX-07-291 Structural studies of EVH2 domain of actin-bundling protein from mouse

Fedorov Hannover

PX-07-292 Protein complexes of bacterial polymerase III Fedorov Hannover

PX-07-293 Hydrogenase maturation protein HypF1 Hoehne Berlin

PX-07-294 Bacterial phytochromes Hoehne Berlin

PX-07-295 Cytosolic 5'-nucleotidase II Nordlund Stockholm

PX-07-296 UDP-glucose pyrophosphorylase (UGP) in

complex with Glucose-1-phosphate and UppNHp

(UMPPNP)

Fedorov Hannover

PX-07-297 Copper chaperones of CCO Mangani Siena

PX-07-298 Phospholipid hydroperoxide glutathione

peroxidase (GPx4)

Hoehne Berlin

PX-07-299 Class D Bel-1 OXA beta-lactamase Mangani Siena

PX-07-300 Class D OXA Ges beta-lactamase Mangani Siena

PX-07-301 Bacterial Thymidylate Synthases Mangani Siena

PX-07-302 outer membrane protein G (OmpG) Kuehlbrandt Frankfurt

PX-07-303 carnitine transporter from E.coli Kuehlbrandt Frankfurt

PX-07-304 Structural investigation of the Betaine carrier BetP from C. bacterium glutamicum

Kuehlbrandt Frankfurt

PX-07-305 Plasma membrane protein ATPase Kuehlbrandt Frankfurt

PX-07-306 Noradrenaline transporter from M. jannasschii Kuehlbrandt Frankfurt

PX-07-307 Natrium-Proton-Antiporter from M. Jannaschii Kuehlbrandt Frankfurt

PX-07-308 light-harvesting chlorophyll a/b protein complex

from plant chloroplasts

Kuehlbrandt Frankfurt

PX-07-309 MMP-12 Matrix metalloproteinase complexes Mangani Siena

PX-07-310 Structural studies of actin assembly regulatory

proteins

Fedorov Hannover

PX-07-311 Cytosolic 5'-nucleotidase III Nordlund Stockholm

PX-07-312 Matrix metalloproteinases 7, 19, 20 Mangani Siena

PX-07-313 ZnuABC proteins Mangani Siena

PX-07-314 RPTP alfa complexes Mangani Siena

PX-07-315 S100 protein and complexes Mangani Siena

PX-07-316 Mammalian phosphodiesterases Podobnik Ljubljana

PX-07-317 Structural studies of dynamin fusion constructs Fedorov Hannover

PX-07-318 Structural investigations of KstD4 Dijkstra Groningen

PX-07-319 Ultra high resolution of human CuZn superoxide Hasnain Cheshire

665

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dismutase and mutants

PX-07-320 Crystallographical study of structure and function

of metalloenzyme hydrogenase

Kuta-

Smatanova

Nove Hrady

PX-07-321 ectoine binding protein Kuehlbrandt Frankfurt am

Main

PX-07-322 Modification in structure and function of haloalkane dehalogenase enyzmes from

Mycobacterium tuberculosis

Kuta-Smatanova

Nove Hrady

PX-07-323 Crystal structure of the TTSS translocator chaperone SycD

Heinz Braunschweig

PX-07-324 NAD-dependent formate dehydrogenase (FDH) Popov Moscow

PX-07-325 Nitrite reductase Popov Moscow

PX-07-326 Light harvesting complexes Popov Moscow

PX-07-327 Crystal structure of TetX monooxygenase Hinrichs Greifswald

PX-07-328 Cross-Linking Drug Interactions with Duplex

DNA

Cardin Reading

PX-07-329 The structure and function of higher order DNA interactions with cytotoxic agents and heavy

metal binding

Cardin Reading

PX-07-330 Protein Crystal Engineering for Drug Delivery Cardin Reading

PX-07-331 X-ray Crystallography of human poly(A)-specific ribonuclease

Song Singapore

PX-07-332 Structural studies of EDC3, a decapping

enhancing protein

Song Singapore

PX-07-333 Acyl-coA synthetase from mycobacterium tuberculosis

Tyagi New Delhi

PX-07-334 bacterioferritin from mycobacterium tuberculosis Tyagi New Delhi

PX-07-335 birA from mycobacterium tuberculosis Tyagi New Delhi

PX-07-336 Determination of the reaction mechanism of

leucine aminopeptidase (ppLAP) from P. putida

Dijkstra Groningen

PX-07-337 Structure determination of mushroom Agaricus

bisporus (champignon) tyrosinase

Dijkstra Groningen

PX-07-338 Structure determination of native, DNA and

inhibitor bound YdaF from L. lactis

Dijkstra Groningen

PX-07-339 Structure of L-Threonine aldolase from Pseudomonas putida

Kratky Graz

PX-07-340 Development of Elogbook and statistics Unge Mikkeli

PX-07-341 Structure of DPP-III from yeast Kratky Graz

PX-07-342 Systematic Study of Protein Crystal Growth -

acquiring baseline dataset for model protein (glucose isomerase)

Wyns Brussel

PX-07-343 Putative Heavy atom ATPase chaperone Nissen Arhus

PX-07-344 Complexes of c-terminal tails of vps10 receptors

and cytoplasmic factors

Nissen Arhus

PX-07-345 Structure determination of the RACK1 protein Nissen Arhus

666

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PX-07-346 transamidosome Nissen Arhus

PX-07-347 Neuronal RNA-Binding Proteins Niessing München

PX-07-348 Structure determination of human Hsps Rabijns Leuven

PX-07-349 Mechanism of Action of HIV Integrase Inhibitors Cherepanov London

PX-07-350 S. aureus thioredoxin Wyns Brussel

PX-07-351 Crystal Structure Determination of Cyclodextrin Inclusion Compounds with Substanses of

Agricultural Interest

Hountas Athens

PX-07-352 Structural determination of the EcoR124I restriction enzyme (HsdR, HsdM and HsdS

subunits)

Kuta-Smatanova

Nove Hrady

PX-07-353 DNA repair protein Jiang Beijing

PX-07-354 Structural Analysis of Bacteriophage Endolysin KMV36C

VanMeervelt Leuven

PX-07-355 Structural Analysis of Bacteriophage Endolysin

EL188

VanMeervelt Leuven

PX-07-356 Synthetic inhibitors of metallocarboxypeptidases Boix Bellaterra

PX-07-357 Struture and function of suppressors of RNA

interference

Chen Frankfurt

PX-07-358 Nucleic acid complexes of Argonaute, the central

enzymatic component of RNAi

Chen Frankfurt

PX-07-359 Elucidation of the 3D structure of murine PAI-1 Rabijns Leuven

PX-07-360 Structures of fructosyltransferases of Cichorium

intybus

Rabijns Leuven

PX-07-361 MASP-1active fragment structure (chimerical) Harmat Budapest

PX-07-362 MASP-1 active fragment Harmat Budapest

PX-07-363 Calmodulin-sphingolipid complex Harmat Budapest

PX-07-364 Crayfish trypsin - BPTI complex Harmat Budapest

PX-07-365 Trypsin proenzyme-like mutant Harmat Budapest

PX-07-366 Two-component regulator protein Jiang Beijing

PX-07-367 Structural investigation with the Cnx1G protein

from Arabidopsis thaliana

Niefind Cologne

PX-07-368 Structure determination of Met2 esterase from Corynebacterium glutamicum

Niefind Cologne

PX-07-369 Fragment-based lead discovery: Screening and

evolving fragments for the inhibition of

thermolysin

Heine Marburg

PX-07-370 Sirtuin Hofmann Bochum

PX-07-371 Carboanhydrase Hofmann Bochum

PX-07-372 Phosphodiesterase Hofmann Bochum

PX-07-373 Cya2 Hofmann Bochum

PX-07-374 CyaC Hofmann Bochum

PX-07-375 Klebsiella phytase Heinemann Berlin

PX-07-376 LlpA, a bacteriocin from Pseudomonas Wyns Brussel

667

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PX-07-377 Dihidropyrimidinase from Sinorhizobium meliloti Wyns Brussel

PX-07-378 PDZ domains from H. sintenyn 1 Wyns Brussel

PX-07-379 Matrix metalloproteinases complexes Mangani Siena

PX-07-380 Novel TGT Inhibitors Heine Marburg

PX-07-381 Novel metal binding sites in CAII and ligand complexes

Heine Marburg

Small Angle X-Ray Scattering SAXS-06-021 SAXS study of conformational changes upon

ligand binding to heterotrimeric 5'-AMP activated

protein kinase

Wallimann Zürich

SAXS-06-104 Structural Studies of the Mycobacterial ACCase Complexes

Wilmanns Hamburg

SAXS-06-105 SAXS studies of the bacteriophage T7

dodecameric portal protein

Vega Barcelona

SAXS-06-106 Effect of site-directed mutations on the domain closure of 3-phosphoglycerate kinase.

Vas Budapest

SAXS-06-107 SAXS studies of the nucleosome remodeling

factor ISWI

Muller Grenoble

SAXS-06-108 Small-angle X-ray scattering studies of Tryptophan Synthase from MTb and its A and B2

subunits

Bartunik Hamburg

SAXS-06-109 Proteins involved in DNA repair Hopfner München

SAXS-06-110 Proteins involved in DNA damage recognition / Checkpoint proteins

Hopfner München

SAXS-06-111 Proteins involved in DNA double strand break

repair

Hopfner München

SAXS-06-112 Prion proteins and its fragments Betzel Hamburg

SAXS-06-113 Solution structure of rubredoxin reductase from Pseudomonas aeruginosa

Heinz Braunschweig

SAXS-07-001 Solution SAXS of mammlian tolloid and bone

morphogenetic protein-1, essential extracellular matrix enzymes

Baldock Manchester

SAXS-07-002 SAXS studies of the nucleosome remodeling

factors ISWI and ACF

Muller Grenoble

SAXS-07-003 SAXS study of the conformational changes of

human 3-phosphoglycerate kinase caused by the

non-natural L-enantiomer of nucleoside diphosphate substrate

Vas Budapest

SAXS-07-004 Effect of site-directed mutations on the domain

closure of 3-phosphoglycerate kinase.

Vas Budapest

SAXS-07-005 SAXS measurement of KorB and its interactions with KorA and with DNA

Scott Sutton Bonington

SAXS-07-006 CtBP/BARS: a dual-function protein involved in

transcription co-repression and Golgi membrane

Bolognesi Milano

668

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fission

SAXS-07-007 Structural analysis of nuclear receptor in complex

with DNA and coactivators

Moras Illkirch

SAXS-07-008 archaeal exosome Hopfner München

SAXS-07-009 Proteins involved in DNA damage recognition /

Checkpoint proteins

Hopfner München

SAXS-07-010 Proteins involved in DNA repair Hopfner München

SAXS-07-011 Proteins involved in DNA double strand break repair

Hopfner München

SAXS-07-012 Using Small Angle X-ray Scattering to study

phosphorylase kinase

Oikonomako

s

Athens

SAXS-07-013 Structural characterisation of human Glucokinase in complexes with natural modulators and

synthetic activators

Oikonomakos

Athens

SAXS-07-014 Determination of the multidomain structure of Amalgam, a soluble neural cell adhesion

molecule

Sussman Rehovot

SAXS-07-015 Solution scattering studies of human cystatin C

(hCC)

Kozak Poznan

SAXS-07-016 The effect of selected cationic surfactants on

formation of DMPC-based bicellar forms

Kozak Poznan

SAXS-07-017 Conformational studies on bacterial virulence factors and interaction with binding proteins and

antimicrobial peptides

Brandenburg Borstel

SAXS-07-018 Solution structures of small heat shock protein and endoglin

Kim Suwon

SAXS-07-019 Structure of a new Ca-dependent lipid-binding C2

domain protein

Gessner Erlangen

SAXS-07-020 Chaperonin GroEL quaternary structure rearrangements and allosteric properties

modifications induced by temperature changes.

Guerin Bilbao

SAXS-07-021 Investigation of solute-solute interactions in aqueous solutions of native and methylated

cyclodextrins

Saenger Berlin

SAXS-07-022 Mammalian lipoxygenases - low resolution structure of native enzyme(s), its mutants and

complexes.

Skrzypczak-Jankun

Toledo

SAXS-07-023 SAXS studies of proteins from the P. syringae Type III Secretion System: folding and

supramolecular structures

Kokkinidis Heraklion

SAXS-07-024 Low resolution structure determination of the complex Fe/S flavoprotein glutamate synthase

and of Mycobacterium tuberculosis glutamyl tRNA synthase

Vanoni Milano

SAXS-07-025 Functional conformational changes of signalling

proteins

Arold Montpellier

669

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SAXS-07-026 Solution structure of p53 and p53/DNA-complex investigated by small-angle X-ray scattering

(SAXS)

Fersht Cambridge

SAXS-07-027 Solution structure of full-length ASPP2 investigated by small-angle X-ray scattering

(SAXS)

Fersht Cambridge

SAXS-07-028 FVII and specific antibody – physiologically and formulation relevant complexes

Vestergaard Copenhagen

SAXS-07-029 Influence of the allosteric inhibitor valine on the

solution structure of acetohydroxyacid synthase from E. coli in dependence on enzyme and proton

co

König Halle/Saale

SAXS-07-030 Effect of phosphate and pyruvamide on the oligomer structure of pyruvate decarboxylase

from N. crassa

König Halle/Saale

SAXS-07-031 Influence of effectors and temperature on the scattering behaviour of oxalyl coA decarboxylase

from E. coli and M. tuberculosis in solution

König Halle/Saale

SAXS-07-032 SAXS Measurements on metallothionein from Triticum durum and G-protein subunits from A.

Thaliana

Sayers Istanbul

SAXS-07-033 Structural Characterization of the Low Molecular Weight Protein Tyrosine Phosphatase oligomeric

species using small-angle x-ray scattering

Bernado Barcelona

SAXS-07-034 Analysis of the lmwPTP equilibrium under the influence of point mutations and small ligands

Bernado Barcelona

SAXS-07-035 Protein fibrillation Vestergaard Copenhagen

SAXS-07-036 Conformational changes of EB1 in protein

interactions regulating microtubule dynamics

Receveur-

Brechot

Marseille

SAXS-07-037 Solution structure of rubredoxin reductase from

Pseudomonas aeruginosa

Heinz Braunschweig

SAXS-07-038 Structures of Engineered Variants of the ColE1

Repressor of Primer Protein (Rop)

Kokkinidis Heraklion

SAXS-07-039 A SAXS study of albumins with antidenaturant agents

Pavel Roma

SAXS-07-040 Adaptor Proteins Vestergaard Copenhagen

SAXS-07-041 Calreticulin functional complexes and tertiary

structural changes

Vestergaard Copenhagen

SAXS-07-042 Structure and conformation of tau protein in solution

Mandelkow Hamburg

SAXS-07-043 Molecular conformation of fractionated

polyphenols from apples and grapes

Zanchi Paris

SAXS-07-044 Solution structure of human collapsin response mediator protein 2

Kursula Oulu

SAXS-07-045 SRB2m Structure Hahn Hamburg

SAXS-07-046 Solution structures of amyloidogenic and non- Damas Porto

670

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amyloidogenic/protective transthyretin variants

SAXS-07-047 SAXS studies of the DNA methyltransferase

MBseCI complexed with DNA

Kokkinidis Heraklion

SAXS-07-048 Structural analysis of RNA binding by PTB and

La

Curry London

SAXS-07-049 Recognition of nervous system-specific targets by calmodulin

Kursula Oulu

SAXS-07-050 Structural characterization of subunit b of the

F1FO ATP synthase from Escherichia coli

Grüber Singapore

SAXS-07-051 Structural investigation of magnetic Co nanoparticle dispersions

Sager Jülich

SAXS-07-052 SAXS analysis of PAMAM dendrimers and

PAMAM dendrimer-Poly U complexes

Bonnete Marseille

SAXS-07-053 SAXS characterization of the cytoplasmic domain

of Neurotactin (Nrt), a natively unfolded protein

Sussman Rehovot

SAXS-07-054 SAXS studies of HDL, a two component system Lee Cleveland

SAXS-07-055 Solution structure of Polo kinases Perrakis Amsterdam

SAXS-07-056 Solution structure of JBP Perrakis Amsterdam

SAXS-07-057 The complex between Geminin and Cdt1 Perrakis Amsterdam

SAXS-07-058 Proteins of the human myelin sheath Kursula Oulu

SAXS-07-059 Using synthetic and natural peptides to control the

structure, assembly and equilibrium of proteins aggregates

Raviv Jerusalem

SAXS-07-060 HSA-insulin complex formation and structure

carboproteins

Arleth Frederiksberg

SAXS-07-061 Solution Structure of PEG Conjugated Hemoglobin

Ekström Umeå

SAXS-07-062 Structural studies of the protein-protein and

protein-ligand complexes involved in translation termination and mRNA decay

song Singapore

SAXS-07-063 MutS and MutL complexes in DNA mismatch

repair

Perrakis Amsterdam

SAXS-07-064 Characterization of microemulsions as precipitatin media for inorganic nanoparticles

Sager Jülich

SAXS-07-065 Structural characterization of NGF-TrkA

interaction in solution

Krastanova Trieste

SAXS-07-066 scPvuII and mutants complexed with DNA Kokkinidis Heraklion

SAXS-07-067 Studies of microbial secreted and surface-associated proteins

Brown London

SAXS-07-068 Morphology of Release Factors (RFs) from

Thermus thermophilus and E.coli

Betzel Hamburg

SAXS-07-069 Solution structure of cell-adhesion proteins from enteropathogenic E. coli and S. pyogenes

Solovyova Newcastle upon Tyne

SAXS-07-070 LcrV, LcrG, Syc's Wilharm Wernigerode

SAXS-07-071 Packing of C-terminal domains of Filamin A Ylanne Jyväskylä

671

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SAXS-07-072 Investigation of the structural organization of complezes of proNGF and some of its binding

partners

Paoletti Rome

SAXS-07-073 Kinesin hetero-tetramers Vestergaard Copenhagen

SAXS-07-074 Solution structure and mechanism of dimerisation of the MET receptor

Gherardi Cambridge

SAXS-07-075 Small angle X-ray scattering study of marine

model proteins

Czjzek Roscoff

SAXS-07-076 S-layer proteins Keller Graz

SAXS-07-077 Manganese stabilizing protein of photosystem II Slowik Berlin

SAXS-07-078 Conformational analysis of oligomers derived from recombinant prion proteins

Betzel Hamburg

SAXS-07-079 Regulation of the Na+/Ca2+ exchanger Hilge Nijmegen

SAXS-07-080 Structure and confomational changes of alpha-

actinins

Djinovic-

Carugo

Vienna

SAXS-07-081 Molecular architecture of focal adhesion adaptor

protein FAP52 and its complex with filamin A

domains 14-16

Djinovic-

Carugo

Vienna

SAXS-07-082 ICBP Samama Illkirch

SAXS-07-083 SAXS studies of NlaX and SsoII (C5-MTases). Bartunik Hamburg

SAXS-07-084 Nanostructured materials based on magnetic core-shell particles and solid polymer electrolytes

Bronstein Bloomington

SAXS-07-085 Structure and characterization of the RuvBL1/2

complex

Carrondo Oeiras

SAXS-07-086 Conformational changes in the Vaccinia virus mRNA capping enzyme upon substrate binding

Cusack Grenoble

SAXS-07-087 Study of Macromolecular Complexes of the Actin

Cytoskeleton Using SAXS

Dominguez Philadelphia

SAXS-07-088 The oligomeric states of Rv0765c from M. tuberculosis

Weiss Hamburg

SAXS-07-089 HsETHE1 Meyer-

Klaucke

Hamburg

SAXS-07-090 Slit and Robo proteins Cusack Grenoble

SAXS-07-091 Effects on single mutations on the structure of the myomesin domains My9-My13

Wilmanns Hamburg

SAXS-07-092 Structural chracterization of type III secretion

translocator chaperone SycD from Yersinia enterocolitica

Heinz Braunschweig

SAXS-07-093 Nano order structure in human bone Bisoyi Rourkela

SAXS-07-094 Global structural study of a fullength GH84

enzyme alone and in complex with its dockerin from C. perfringens using SAXS experiments

Czjzek Roscoff

SAXS-07-095 The Polycomb proteins Ring1b and Bmi1 Perrakis Amsterdam

SAXS-07-096 Plant SCF E3 ligase Perrakis Amsterdam

SAXS-07-097 DNA interactions of RepB Coll Barcelona

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SAXS-07-098 Aerobic T4 RNR Thelander Umea

SAXS-07-099 Solution structures of Reptin Kim Suwon

SAXS-07-100 Solution structure of Z-DNA bound Z-DNA binding domains

Kim Suwon

SAXS-07-101 SAXS solution structures of proteins involved in

human pathogenesis

vanAalten Dundee

SAXS-07-102 ScCHS2 and hOGT vanAalten Dundee

SAXS-07-103 Studies of the structure of eRF1•eRF3, eRF1•eRF3•GTP and eRF1•eRF3•GDP

complexes.

Pestova Brooklyn

SAXS-07-104 SAXS analysis of recombinant proteins from HCV and HIV

LaPlante Laval

SAXS-07-105 Resuscitaion Promoting Factors from M.

tuberculosis

Berisio Napoli

SAXS-07-106 SAXS study of the LysR Transcriptional Regulator TsaR

Uson Barcelona

SAXS-07-107 heparin-binding hemagglutinin adhesin Berisio Napoli

SAXS-07-108 Transient Protein Interactions: Cytochrome c and

Flavodoxin

Crowley Dublin

SAXS-07-109 Structural characterization of Fatty Acid Amide Hydrolase in Solution

Dainese Teramo

SAXS-07-110 Structural characterization of matrix

Metalloproteinases

Bertini Sesto Fiorentino

SAXS-07-111 Structural Characterization of Human Menkes ATPase ATP7A

Bertini Sesto Fiorentino

SAXS-07-112 Structural studies on the HsdR DEAD-box

subunit of the EcoR124I endonuclease

Kuta-

Smatanova

Nove Hrady

SAXS-07-113 Characterization of the structure of FMRP Pastore London

SAXS-07-114 Cold denatiration studies of YFH1 Pastore London

SAXS-07-115 SAXS structure of the GRD-Sec-PH portion of

neurofibromin

Scheffzek Heidelberg

SAXS-07-116 Structure of the p110/p85 heterodimeric

phosphoinositide 3-kinase (PI3K)

Williams Cambridge

SAXS-07-117 Stucture analysis of the chemokines SDF-1 and MCP-1 in complex with their Spiegelmers

Betzel Hamburg

SAXS-07-118 Solution structure of two DegP-OmpC complexes Clausen Vienna

SAXS-07-119 AMIGO and RAGE solution studes Kajander Helsinki

SAXS-07-120 Soy Glycinin (11S) and the effect of

concentration, pH and anion type.

Gilbert Sydney

SAXS-07-121 Comparitive structure of single stranded DNA binding proteins from different Herpes Virus

families

Tucker Hamburg

SAXS-07-122 Structural studies of human ATP-citrate lyase Savvides Ghent

SAXS-07-123 Solution structure of truncated- and single-

enzyme-human PDC core

Byron Glasgow

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SAXS-07-124 SAXS analysis of the oligomerization process in the human Ca(2+)-ATPase

Benetti Padua

SAXS-07-125 Salting in effect on rasburicase observed via

interaction measurements

Bonnete Marseille

SAXS-07-126 The MIP1-MLP complex Wilmanns Hamburg

SAXS-07-127 Protein-protein interactions in plant fatty acid metabolism

Henriksen Valby

SAXS-07-128 Interactions between Nucleoplasmin and Histones Taneva Leioa

SAXS-07-129 Polymerization of Yersinia enterocolitica

virulence protein YscY

Wilharm Wernigerode

SAXS-07-130 Complement C3 Convertase Formation Gros Utrecht

SAXS-07-131 The quaternary structure of the coupling protein TrwB and ClpB chaperone

Guerin Bilbao

SAXS-07-132 Structural studies of the Mediator complex Cramer Munich

X-Ray Spectroscopy XAS-06-039 Structural studies of the iron-pyoverdine outer

membrane receptor from Pseudomonas

aeruginosa

Cobessi Illkirch

XAS-06-040 Mutants of membrane-bound Ni-Fe hydrogenase with increased H2 production activity and

enhanced O2 tolerance studied by Ni XAS

Haumann Berlin

XAS-06-041 Analysis of the mechanism of CO oxidation at the [Ni-4Fe-5S] active site of the CO

dehydrogenase II from Carboxydothermus hydrogenoformans by EXAFS

Meyer Bayreuth

XAS-06-042 Interaction of cyanide and cyanate with the [Ni-

4Fe-5S] active site cluster of CO dehydrogenase from Carboxydothermus hydrogenoformans

Meyer Bayreuth

XAS-07-001 The binuclear active site of ElaC1: selectivity of

metal binding and catalysis

Achard Hamburg

XAS-07-002 Mn-Ribonucleotide reductase of Corynebacterium ammoniagenes

Auling Hannover

XAS-07-003 Biological EXAFS studies at the Br and I K edge

of organic halogen pooling processes in a marine brown algal pathosystem

Kuepper Oban

XAS-07-004 Identifying the active site of Human Prolidase Morante Roma

XAS-07-005 Functional and structural characterization of the

zinc high-affinity binding site in rhodopsin by

EXAFS and XANES

Sepulcre Barcelona

XAS-07-006 Ligand system of iron center in iron/sulfur

cluster-free hydrogenase (Hmd)

Shima Marburg

XAS-07-007 XAS of KP46 (Ga tumor inhibiting compound) to

study its coordination in cells

Rompel Münster

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XAS-07-008 Platinum cellular transport: the interaction of Pt-drugs with intra-cellular platinophiles and

proteins involved in copper trafficking.

Borghi Rome

XAS-07-009 KP1019 a Ru containing tumor inhibiting

compound and its coordination in cells studied by X-ray absorption spectroscopy

Rompel Münster

XAS-07-010 The Mn-complex of oxygenic photosynthesis

studied by extended-range EXAFS on unidirectionally oriented PSII-particles

Dau Berlin

XAS-07-011 Ligands involved in plant copper resistance Küpper Konstanz

XAS-07-012 Role of Nicotianamine in heavy metal

detoxification

Küpper Konstanz

XAS-07-013 Oncoproteins E6&E7 Görlach Jena

XAS-07-014 Structural properties of miniaturized metalloproteins

Lombardi Naples

XAS-07-015 Zinc sensors and zinc chaperones Mangani Siena

XAS-07-016 Copper trafficking proteins Mangani Siena

XAS-07-017 Prion proteins and its fragments Betzel Hamburg

XAS-07-018 XAS on Zincosomes in Marcophages Haase Aachen

XAS-07-019 EXAFS Studies on the Diiron Centre of

Escherichia coli YtfE

Saraiva Oeiras

XAS-07-020 Structural studies of the iron-pyoverdine outer membrane receptor from Pseudomonas

aeruginosa

Cobessi Illkirch

XAS-07-021 Interaction of cyanide and cyanate with the [Ni-4Fe-5S] active site cluster of CO dehydrogenase

from Carboxydothermus hydrogenoformans

Meyer Bayreuth

XAS-07-022 Interaction of methyl group, CO, and coenzyme A with the Ni-Ni-[4Fe-4S] active site cluster of

acetyl-CoA-synthase from Carboxydothermus hydrogenoform

Meyer Bayreuth

XAS-07-023 The chelation properties of an iron binding

periplasmic protein.

Schalk Illkirch

XAS-07-024 UreG, a metallochaperone in the urease in vivo

assembly

Ciurli Bologna

XAS-07-025 Human Primase p58 Görlach Jena

XAS-07-026 Molybdate and tungstate binding proteins with

octahedral metal sites

Feiters Nijmegen

XAS-07-027 XAFS characterization of novel mixed

manganese-iron site of Chlamydia rinucleotide

reductase

Dau Berlin

XAS-07-028 Evaluation of metal ion coordination spheres in plant metallothioneins

Freisinger Zürich

XAS-07-029 Exploring the metal binding site of non-heme

iron dependent enzymes

Straganz Graz

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XAS-07-030 Oxo Transfer Catalytic Mechanism of Molybdewnum Cofactor Models

Schulzke Göttingen

XAS-07-031 Mutants of membrane-bound Ni-Fe hydrogenase

with increased H2 production activity and enhanced O2 tolerance studied by Ni XAS

Haumann Berlin

XAS-07-032 Directed Evolution of Hybrid Catalysts Podtetenieff Mülheim an der

Ruhr

676