new product of selleck-quercetin(purity>>99%)
DESCRIPTION
Quercetin is a PI3K and PKC inhibitor with IC50 of 3.8 μM and 15µg/ml. It strongly abrogated PI3K and Src kinases, mildly inhibited Akt1/2, and slightly affected PKC, p38 and ERK1/2.TRANSCRIPT
Product Information
Quercetin is a PI3K and PKC inhibitor with IC50 of 3.8 μM and 15µg/ml. It strongly abrogated PI3K and Src kinases, mildly inhibited Akt1/2, and slightly affected PKC, p38 and ERK1/2. [1][2]
Quercetin is a naturally-occurring polar auxin transport inhibitor with IC50 of 0.8, 16.7, 6.1, 11.36 µM for the inhibition of LDH% release, the inhibition of TNF-induced PMN-EC adhesion, TNF-induced inhibition of DNA synthesis and proliferation. It is a type of plant-based chemical, or phytochemical, known as a flavonol and a plant-derived flavonoid found in fruits, vegetables, leaves and grains. It also may be used as an ingredient in supplements, beverages or foods. In several studies, it may have anti-inflammatory and antioxidant properties, and it is being investigated for a wide range of potential health benefits. [3][4]
Biological Activity
[1] Sidhu JS et al. Mol Pharmacol. 2001 May; 59(5):1138-46.
[2] Navarro-Núñez L et al. Fitoterapia. 2010 Mar; 81(2):75-80.
[3] Yu XB et al. Yao Xue Xue Bao. 1996; 31(3):176-81.
[4] http://en.wikipedia.org/wiki/Quercetin
References
S2391 Quercetin
Technical Data:M.Wt:Formula:Solubility:Purity:Storage:CAS No.:
302.24C15H10O7
Unknown99%at -20℃ 2 years117-39-5
Notes
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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Synonyms: Sophoretin, Meletin, Quercetine
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