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ACC New York, Dec 10, 2017 No Disclosures New Frontiers in CVD Aging / Disease - Youth / Health Science Health Education

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Page 1: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

ACC New York, Dec 10, 2017 No Disclosures

New Frontiers in CVD Aging / Disease - Youth / Health

Science Health Education

Presenter
Presentation Notes
Page 2: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

Aging / Disease - Youth / Health

B

B

BProm.

HealthSubcl.

DiseaseStable

Disease

WindowYoung

Our Future

Behav.Change

AdherenceSimplicity

25 50 100

25 50 100

A

Present

Too Late Earlier

1. EconomicA

A0

2. Scientific

V Fuster, JACC 2015; 66: 1627

EnvironmentHealth Policy

3. Educational

0

Presenter
Presentation Notes
0
Page 3: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

Primordial

SecondaryPrimary

50/50

From Aging / Disease to Youth / Health

6) SHE

7) HARLEMVILLAGEMEXICO

4) 1)

2)

5) IIIP

HRP

Surgery InterventionPharmacology.ImagingGenetics/Tr

PESA AWHS TANSNIP

3) AGING )

NHLBI $-1

50-100 yrs

25-50 yrs

00-25 yrs

Page 4: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

JN Giedd. Scientific American 2015;312:32

6). Child’s Brain Development Less Networking Brings Atention

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GENERALPUBLIC

3-5CHILDREN 6-8 9-14

EDUCATIVE GOAL: HEALTHY HABITS FOR CHILDREN BETWEEN 3 & 5 YRS

6a).COLOMBIA – CHILDREN’S PROGRAM

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In Children’s KAH Mean Scores*

40.0

50.0

60.0

70.0

80.0

90.0

100.0

0 18 36

Scor

e (m

ean)

Knowledge Attitudes Habits (physical activity)

p< 0.001p< 0.001

p< 0.001

p< 0.001

p< 0.001

The Amer J of Med 2012; 126, 27The Amer J of Med 2013;126:1122Bogota – 25,000

Presenter
Presentation Notes
Adjusted by sex and age of children, group, socioeconomic status, age of parents, age and educational level of teachers . Ɨ Habits in physical activity. ǂ Standard error
Page 7: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

JL Peñalvo, V Fuster et. al. JACC 2015;65:1065. - 10,000,

6b). Changes In Anthropometric Variables At Each FU In Overweight Children

Body Mass Index (BMI)

Waist Circumference (WC)

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CHILDREN’S – BOGOTA, SPAIN, NEW YORK – N = 50,000

The Amer J of Med 2013;126:1122 - J. Amer. Coll. Card. 2015;65:1065J. Amer. Coll. Card. 2017(In Press)

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Page 10: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

CHILDREN’S PROGRAM - SPAIN

10

Page 11: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

Primordial

SecondaryPrimary

50/50

From Aging / Disease to Youth / Health

6) SHE

7) HARLEMVILLAGEMEXICO

4) 1)

2)

5) IIIP

HRP

Surgery InterventionPharmacology.ImagingGenetics/Tr

PESA AWHS TANSNIP

3) AGING )

NHLBI $-1

50-100 yrs

25-50 yrs

00-25 yrs

Page 12: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

BARRIERS TO IMPLEMENTATION OF A HEALTH PROMOTION PROGRAM IN HARLEM, NY

THE FAMILIA STUDYAn AHA Strategically Focused Research Network Study

Sameer Bansilal, MD, MS, Rajesh Vedanthan, MD, MPH, Risa Jaslow, MS, RDN, Martha Hadley, PhD, Amy Siskind, PhD, Carmina Marcial, MA, Ana Victoria Soto,

MD, Claire Kofler, BS, Zahi A Fayad, PhD, Valentin Fuster, MD,PhD

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O

Start

Start

Children3 Groups

Caregivers3 Groups

PPP

PPP

Teachers

OI I

IOO

OO O

O

OOO

O

KAH-BEAMol. Genomics KAH-BEA S-KAH-BEA

BEWATPoint of Care.

3D-USMol. Genomics

OIPII II

O

IP

Contr./Interv.

S-BEWATPoint of Care

BEWATPoint of Care

3D-US Mol. Genomics

1st Yr 2nd Yr 3rd Yr 4th Yr

Intervention.Intervention

Control

IIIPPPPI

KAH-BEA = Knowledge, Attitude, Habit, -BMI, Exercise, Alimentation ; FUSTER-BEWAT = BP, Exercise, Weight, Alimentation, Tobacco; S=Sustained

(1)

(2)

(3)

(3)(1)

(2)

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Lanzamiento de la versión internacional THE CIRCLE OF HEALTH

Actividades previstasInteractive “Circle of Health” - App

www.thecircleofhealth.org

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Children’s Health & Biology: The Effect of DisparitiesIcahn School of Medicine at Mount Sinai ( ISMMS)

December 13th, 2017

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16

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Project I: Background

17

Fuster V et al. Am Heart J. 2017;187:170-181

Har

lem

, NY

Colo

mbi

a

Fuster V et al. Am J Med. 2013;126(1):27-35

Spai

n

Fuster V et al. J Am Coll Cardiol.2015;66(14):1525-34

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Project I: Aims

18

Objective: The effect of disparities on CHILDREN's HEALTHoutcomes following a health promotion educational intervention in preschool children.

Variables modulating such outcomes:Aim 1. Impact of socio-economic differences at the family level.

Aim 2. Factors that impact the teachers’ efficacy in implementing the educational intervention and health outcomes in children.

Aim 3. Effect of school environment in implementing the educational intervention and health outcomes in children.

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Project I: Methods and Feasibility

19

CHILDREN´SHEALTH

Socio-economic (Family)

SchoolTeachers

• Prospective educational intervention• Public preschools in all five boroughs of NYC• Children between 3 and 5 years of age• Evidence-based health promotion

educational curriculum• Duration of intervention: 5 months• Follow-up: 24 months

• Variables impacting children´s health1. Socio-economic 2. Teachers 3. School environment

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Primordial

SecondaryPrimary

50/50

From Aging / Disease to Youth / Health

6) SHE

7) HARLEMVILLAGEMEXICO

4) 1)

2)

5) IIIP

HRP

Surgery InterventionPharmacology.ImaginGenetics/Tr

PESA AWHS TANSNIP

3) AGING )

NHLBI $-1

50-100 yrs

25-50 yrs

00-25 yrs

Page 21: New Frontiers in CVD Aging / Disease - Youth / Health › ~ › media › Non-Clinical › Files-PDFs-Excel... · 2017-12-10 · ACC New York, Dec 10, 2017 No Disclosures New Frontiers

21Confidential, for Internal and Investigator use only

CARDONA MEXICO

PERU ?

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EDUCATION (7)CARDONA – MEXICO – PERU ?

HARLEM

US -SPAINGRENADA - SPAIN

KENYA

SPAINBOGOTA

Con

tinu

ity

Villages(3)

Family (1)

Adults (5)

Children (2)

CONCEPTS, SCIENTIFIC STUDIES, NPOs

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Global Health Future Role of the United States

National Academies of Sciences, Engineering & MedicineNew Engl. J. Med. 2017; 377:1292 - JACC 2017 (In Press)

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Report Conceptual Model

26Maximizing Return

Catalyzing Innovation G.H. Leadership Smart Financing

Global Health

Security

Continuous Communicable

Threats

Saving and

Improving the Lives of Women

and Children

Promoting Cardiovascular

Health and Preventing

Cancer

SECURING AGAINST GLOBAL THREATS

ENHANCING PRODUCTIVITY AND ECONOMIC GROWTH

Presenter
Presentation Notes
10 chapters, 14 recommendations Introduction and Rationale for Investing in Global Health, Chapter 1 & 2 Securing Against Global Threats (Acute and Continuous), Chapter 3 & 4 Enhancing Productivity and Economic Growth, Chapter 5 & 6 Maximizing Returns, Chapter 7, 8, 9 Summary and Conclusion, Chapter 10
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Lancet 2017; 389: 77

Lancet 2017; 389: 91

Lancet 2017; 389: 103

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1. Nutrition & Diet 2. Healthy Weight 3. Exercise & Physical Activity 4. Tobacco-Free Lifestyle 5. Blood Pressure 6. Cholesterol7. Blood Sugar8. Psychological Health

Cardiovascular Health PromotionEight Factors to be Addressed

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Cardiovascular Health PromotionFour Questions to be Answered

1. Pathophysiological Effects: Detrimental impact that adverse RFs & behaviors can cause to the CV system, from molecular to clinical levels

2. Mechanistic/Triggering Factors: Desmotivators of good health: at personal, community or societal levels.

3. Role of Preventive Action: Motivators of good health: at personal, community/educational or societal/authoritative

4. Competencies for training: Standarized methods of education that impact on health promotion.

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ACC New York, Dec 10, 2017 No Disclosures

New Frontiers in CVD Aging / Disease to Youth / Health

Science Health Education

Presenter
Presentation Notes