Generic Name

Brand Name

Classification

Indication Action Adverse Reaction

Time & Dosage

Nursing Consideration

omeprazolesodium

Antiulcer

Proton pumpinhibitorPregnancy risk category C

-Symptomatic gastroesophageal refluxdisease (GERD) without esophageallesions

-Erosive esophagitis and accompanyingsymptoms caused by GERD

-Maintenance of healing erosiveesophagitis

Inhibits proton pump activity by bindingto hydrogen-potassium adenosine triphosphatase,located at secretory surface ofgastric parietal cells, to suppress gastric acidsecretion.

CNS: asthenia, dizziness, headache.GI: abdominal pain, constipation, diarrhea,flatulence, nausea, vomiting.Musculoskeletal: back pain.Respiratory: cough, upper respiratory tractinfection.Skin: rash.

4g IM

IVTT

• Dosage adjustments may be necessaryin Asians and patients with hepatic impairment.Alert: Amoxicillin may trigger anaphylaxisin patients with a history of penicillinhypersensitivity.• Drug increases its own bioavailabilitywith repeated doses. Drug is unstable ingastric acid; less drug is lost to hydrolysisbecause drug increases gastric pH.• Gastrin level rises in most patients duringthe first 2 weeks of therapy.• Look alike–sound alike: Don’t confusePrilosec with Prozac, Prilocaine, or Prinivil

Generic

Brand

Classification

Indication Action Adverse Reactio

Time & Dosag

Nursing Consideration

Name Name n e

Acetaminophen

paracetamol

Analgesic

Para-aminophenolderivativePregnancy risk category B

-Mild pain or fever

Thought to produce analgesia by inhibitingprostaglandin and other substances that sensitizepain receptors. Drug may relieve feverthrough central action in the hypothalamicheat-regulating center.

Hematologic: hemolytic anemia, leukopenia,neutropenia, pancytopenia.Hepatic: jaundice.Metabolic: hypoglycemia.Skin: rash, urticaria.

50mg

Q4

IVTT

Alert: Many OTC and prescriptionproducts contain acetaminophen; be awareof this when calculating total daily dose.• In children, don’t exceed five doses in24 hours.

Generic Name

Brand Name

Classification Indication Action Adverse Reaction

Tramadol Analgesics

Synthetic, centrally active analgesics

Pregnancy risk category C

-Moderate to moderately severe chronic pain

Unknown. Thought to bind to opioid receptorsand inhibit reuptake of norepinephrineand serotonin.

CNS: dizziness, headache, somnolence,vertigo, seizures, anxiety, asthenia, CNSstimulation, confusion, coordination

disturbance,euphoria, malaise, nervousness,sleep disorder.CV: vasodilation.EENT: visual disturbances.GI: constipation, nausea, vomiting, abdominalpain, anorexia, diarrhea, dry mouth,dyspepsia, flatulence.GU: menopausal symptoms, proteinuria,urinary frequency, urine retention.Musculoskeletal: hypertonia.Respiratory: respiratory depression.Skin: diaphoresis, pruritus, rash.

Generic Name

Brand Name

Classification Indication Action Adverse Reaction

Nicardipine

2mg

IVTT

Antihypertensive

Calcium Channel Blocker

Pregnancy risk category C

-Chronic Angina (used alone with other antianginals)

Inhibits calcium ion influx across cardiacand smooth muscle cells but is moreselective to vascular smooth muscle than cardiac muscle. Drug also dilates coronaryarteries and arterioles.

CNS: headache, dizziness, lightheadedness,asthenia.CV: peripheral edema, palpitations, flushing,angina, tachycardia.GI: nausea, abdominal discomfort, drymouth.Skin: rash.

Generic Name

Brand Name

Classification Indication Action Adverse Reaction

metoprolol

1mg

IVTT

Antihypertensive

Selective Beta Blocker

Pregnancy risk category C

-Hypertension-Early intervention in acute MI

Unknown. A selective beta blocker thatselectively blocks beta1 receptors; decreasescardiac output, peripheral resistance, andcardiac oxygen consumption; and depressesrenin secretion.

CNS: fatigue, dizziness, depression.CV: hypotension, bradycardia, heartfailure, AV block, edema.GI: nausea, diarrhea, constipation, heartburn.Respiratory: dyspnea, wheezing.Skin: rash.