nehal n. mehta, md, msce, faha page 1 nehal n. mehta, md ... … · 2006 american college of...

Nehal N. Mehta, MD, MSCE, FAHA

National Institutes of Health, National Heart, Lung, and Blood Institute

Curriculum Vitae

Date: 3/2/2015


Address: 10 Center Drive CRC, Room 5-3140 National Institutes of Health

Bethesda, MD 20892 USA Phone: 301-827-0483 Fax: 301-827-0915 Email: [email protected]

Education: 1997 BA The George Washington University (Seven-Year Accelerated

Medical Program) (Neuropsychobiology) 1997 NA Oxford University (Biochemistry) 2001 MD The George Washington University Medical School

(Medicine) 2009 MSCE University of Pennsylvania, Center for Clinical Epidemiology

and Biostatistics (Genetic Epidemiology) Postgraduate Training and Fellowship Appointments: 2001-2002 Internship in Internal Medicine, Hospital of University of

Pennsylvania 2002-2004 Residency in Internal Medicine, Hospital of University of

Pennsylvania 2004-2005 Chief Medical Resident, Hospital of the University of

Pennsylvania 2005-2007 Fellow in Cardiovascular Medicine, Hospital of the University

of Pennsylvania 2006-2007 Chief Fellow in Cardiovascular Medicine, Hospital of the

University of Pennsylvania 2007-2009 Post-doctoral Research Fellow in Cardiovascular

Medicine/Fellow in Genetic Epidemiology, Center for Clinical Biostatistics and Epidemiology, University of Pennsylvania

2007 Course on Genetics of Diabetes, Columbia University 2007 Course on Complex Heart, Lung and Blood Disorders, The

Jackson Laboratory 2007 Course on Clinical Cardiovascular Genomics, Cold Spring

Harbor 2008 Cohort Study Conference on Cardiac Diseases, National Heart,

Lung and Blood Institute

mailto:[email protected]

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Faculty Appointments: 2004-2005 Clinical Instructor in Medicine, University of Pennsylvania

School of Medicine 2009-2012 Instructor A in Cardiovascular Medicine, University of

Pennsylvania School of Medicine 2009-present Adjunct Scholar, Center for Clinical Biostatistics and

Epidemiology, University of Pennsylvania School of Medicine 2012-present Adjunct Assistant Professor, University of Pennsylvania

School of Medicine 2013-present

2014-present

Clinical Associate Professor of Medicine, The George Washington University School of Medicine and Health Sciences Clinical Professor of Medicine, The George Washington University School of Medicine and Health Sciences

Hospital and/or Administrative Appointments: 2007-2012 Attending Physician, Division of Cardiology, Pennsylvania

Hospital 2008-2012 Attending Cardiologist, Pennsylvania Hospital, University of

Pennsylvania 2008-2012 Director, Cardiology Advanced Practitioner Services 2009-2012 Attending Cardiologist, Hospital of the University of

Pennsylvania 2009-present Director, Inflammatory Risk, Preventive Cardiology, Hospital

of the University of Pennsylvania 2012-present Chief, Section of Inflammation and Cardiometabolic Diseases,

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health

Specialty Certification: 2004 American Board of Internal Medicine (Internal Medicine) 2007 National Board of Echocardiography (Level II

Echocardiography) 2007 American Society of Nuclear Cardiology (Nuclear

Cardiology) 2008 American Board of Internal Medicine (Cardiovascular

Diseases) Licensure: 2005-Present Pennsylvania State Board of Medicine Awards, Honors and Membership in Honorary Societies: 1991 Eagle Scouts of America Award 1995 National Collegiate Scholar 1996 Psi Chi Psychology Honors Society, The George Washington

University


1996 Phi Beta Kappa, The George Washington University 1997 Summa Cum Laude, The George Washington University 1997 Hertford College Scholar Award, Oxford University 1998 WT Gill Research Fellowship, The George Washington

University 2000 William Beaumont Research Honors Society, The George

Washington University 2001 Kane King Dodek Obstetrical Honors Society The George

Washington University 2001 MD with Distinction, The George Washington University 2005 Edward W. Holmes Resident Research Award, Hospital of the

University of Pennsylvania 2006 American College of Cardiology/Merck Award for Metabolic

Syndrome Research 2006 Basic Science Teaching Award - Best Section Leader,

University of Pennsylvania School of Medicine 2007 Nominee, Best Section Leader, University Of Pennsylvania

School of Medicine 2007 Fellow, American College of Physicians 2008 Junior Investigators Pilot Grant Award, University of

Pennsylvania Clinical Translational Research Center 2008 Finalist, Northwestern University Young Investigators Forum 2008 Fellow, American College of Cardiology 2008 Fellow Research Award, Division of Cardiovascular

Medicine, Penn Cardiovascular Institute 2009 Best abstract, Gordon Conference on Atherosclerosis 2009 Future Leader in Cardiovascular Research Award 2009 Leadership Council in Cardiovascular Medicine National

Research Award (declined due to K23) 2009 Fellow, American Heart Association 2009 Dr. Madhukar Deshmukh Research Award, Best Abstract

Clinical Research in Preventive Cardiology, American Association of Cardiologists of Indian Origin

2009 First Prize, Northwestern University Young Investigators Forum, Best Clinical Research

2010 Jeremiah Stammler Research Award, Northwestern University Young Investigators Symposium, Best Faculty Research

2010 Bradley Award, Best Young Investigator, Junior Faculty, Department of Medicine, University of Pennsylvania

2012 2014

Lasker Clinical Research Scholar Award, The National Institutes of Health, National Heart, Lung, and Blood Institute IPC Councilor, International Psoriasis Council

Memberships in Professional and Scientific Societies and Other Professional Activities:

National: 1997-Present American Medical Association (Member)


1999-Present American College of Physicians (Member (1999-present); Fellow (2007-present) 2004-Present American Heart Association Council on Prevention/Epidemiology (Member); Chair,

Early Career Committee (2010-2012) 2005-Present American College of Cardiology (Fellow) 2005-Present American Society of Echocardiography (Member) 2007-Present American Society of Nuclear Cardiology (Member) 2010-Present American Heart Association Awards & Lectures Committee (Member) 2011-Present 2014-Present 2014-Present 2014-2016 2014-Present

American Heart Association Research Committee (Member) European Society for Translational Medicine (Member) National Psoriasis Foundation (NPF) Medical Board (Member) American Heart Association Awards & Lectures Committee (Chair) American College of Cardiology ACC.15 Program Committee (Member)

Local: 1997-2001 Medical Society of Washington DC (Member) 2001-2012 Pennsylvania Medical Society (Member) Reviewer/Editorial Positions: 2005-Present Editorial Staff, First Aid Clinical Cases, Cardiovascular Series 2006-Present Reviewer, Journal of the Cardiometabolic Syndrome 2006-Present Reviewer, International Journal of Cardiology 2006-Present Reviewer, Circulation 2006-Present Reviewer, American Journal of Cardiology 2006-Present Consulting Editor, Handheld Books, Cardiovascular Series 2008-Present Reviewer, Journal of American College of Cardiology 2008-Present Reviewer, Journal of Pharmacoepidemiology 2009-Present Reviewer, J of European Acad of Derm and Venereology 2009-Present Reviewer, Journal of Rheumatology 2009-Present Reviewer, Journal of Obesity 2009-Present Reviewer, Circulation CV Genetics 2009-Present Reviewer, PLoS One 2010-Present Reviewer, British Journal of Dermatology 2010-Present Reviewer, Abstracts of the American Heart Association 2010-Present Reviewer, Abstracts of the American College of Cardiology 2010-Present Reviewer, Atherosclerosis 2010-Present Reviewer, British Medical Journal 2010-Present Reviewer, American Heart Journal 2011-Present Reviewer, Journal of Clinical Lipidology 2011-Present Reviewer, JAMA 2011-Present Reviewer, Abstracts of the AHA Epidemiology Meeting 2011-Present Associate Editor, BMC Cardiovascular Diseases 2011-Present Associate Editor, Journal of Cardiovascular Diseases 2012-Present

Section Editor, Journal of Translational Medicine, Section of

Cardiovascular, Lipoprotein and Metabolic Translation 2012-Present Editorial Board Member, Heart Insight Magazine


2012-Present

2012

2013 Abstract Reviewer, American Heart Association: Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism Scientific Sessions (EPI/NPAM) Reviewer, ACC.14 Program Committee

2013

2013 National Psoriasis Foundation Discovery and Translational Grant Application Reviewer

2013 Editorial Board Member, JSM Genetics and Genomics, Journal of Immunology & Clinical Research

2013 2013-2015 2013-present 2013-present 2013-present 2013-present 2014-present 2014-present 2014-present 2014-present 2014-present 2014-present 2014-present 2014-present 2014-present 2014-present 2014-present 2014-present

Reviewer, American Heart Association’s Genomics & Translational Epidemiology & Observational Epidemiology – Population Science 1 Peer Review Committee, Fall 2013 Epidemiology & Prevention Council’s Prevention Science Committee (Member) Editorial Board Member, Insights of Translational Medicine Editorial Board Member, World Journal of Cardiology Editorial Board Member, Austin Journal of Immunology Editorial Board Member, Journal of Cardiology and Therapy Editorial Board Member, Journal of Geriatric Cardiology Grant reviewer, The Netherlands Organization for Health Research and Development (ZonMw) Editorial Board Member, International Scholarly Research Notices Editorial Board Member, International Journal of Cardiology and Research Editorial Board Member, Insight Knowledge Reviewer, American Heart Association for Strategically Focused Network on Prevention Editorial Board Member, Journal of Experimental Dermatology and Clinical Research Editorial Board Member, Journal of Medical Genomics and Biomarkers (MGB) Editorial Board Member, American College of Cardiology Prevention Clinical Topic Collection Editorial Board Member, Global Journal of Obesity, Diabetes, and Metabolic Syndrome Editorial Board Member, Journal of Immunology and Immunotherapeutics Editorial Board Member, CYTOKINE

Academic and Institutional Committees: 2001-2002 Intern Steering Committee, Department of Medicine, Hospital of the

University of Pennsylvania 2002-2005 Resident Steering Committee, Department of Medicine, Hospital of

the University of Pennsylvania 2008-Present Director, Cardiology Advanced Practitioner Service


Major Academic and Clinical Teaching Responsibilities: 2000-2001 Clinical instructor to 1st and 2nd year students in physical

examination and history taking. 2000 Internal Medicine Curriculum Committee representative to develop

clinical skills; reviewed a chest x-ray class and EKG class. 2001 EKG reading skills workshop for the 3rd year clinical clerks. 2002 Department of Medical Genetics Grand Rounds, University of

Pennsylvania, Conference on Hereditary Hemorrhagic Telangiectasia, "Pulmonary Venous Aneurysms Detected by Time-Resolved MRA"

2002 EKG digitizer for medical resident and cardiovascular fellow conferences under Ralph Verdino, MD.

2004-2012 Lecturer, Department of Ob/Gyn, peri-operative cardiac diseases 2004-2005 Chief Medical Resident, Hospital of the University of Pennsylvania 2005 Department of Medicine Grand Rounds, University of Pennsylvania.

"38th Tri-annual Chief Medical Resident Clinical Pathological Conference"

2005 Division of Cardiology and Cardiothoracic Surgery, University of Pennsylvania. "Massive Pericardial Effusion 3 months after aortic root surgery"

2005-2012 Medical student clinical cardiovascular auscultation seminar, "Harvey", School of Medicine, University of Pennsylvania

2006 Division of Cardiology and Cardiothoracic Surgery, University of Pennsylvania. "Atrioventricular Septal Defect"

2006 Division of Cardiology and Cardiothoracic Surgery, University of Pennsylvania. "Ischemic mitral regurgitation"

2006 Division of Cardiology and Cardiothoracic Surgery, University of Pennsylvania. "Management of Malignant Pericardial Effusion"

2006-2012 Small-group leader for 14 lectures yearly, Basic Science Cardiovascular Module, School of Medicine, University of Pennsylvania

2010-2012 Small-group leader, Penn Epidemiology course, first-year medical students

Lectures by Invitation: Jun, 2005 "Training at the Hospital of the University of Pennsylvania: Why

cardiology?", Penn Medicine Board of Trustees; Philadelphia, PA Jun, 2005 "Adiposity and pro-atherosclerotic responses to an Innate Immune

Challenges in Humans", University of Pennsylvania Holmes Research Day; Philadelphia, PA

Apr, 2006 "Modulation of the Insulin Signaling Pathway in Human Inflammation", Atherosclerosis, Thrombosis and Vascular Biology of the American Heart Association; Denver CO

Nov, 2006 "The Effect of PKC-Inhibition on Macrovascular Function in Patients with Type 2 Diabetes", American Heart Association; Chicago IL


Jun, 2007 "Understanding Diabetic Coronary Risk", Atlantic United Coder and

Abstracter Conference Keynote Speaker; Philadelphia, PA. Nov, 2007 "Very-low Dose Endotoxemia Induces Insulin Resistance in the

Absence of Clinical Inflammatory Responses", American Heart Association; Orlando FL

Jun, 2008 "Diabetic Coronary Disease and Complications", Atlantic City Medical Center Medical Grand Rounds; Atlantic City, NJ

Mar, 2009 "Human Translational Studies of a Novel Atherosclerosis Locus", Future Leaders of Cardiovascular Research; Orlando, FL

Jun, 2009 "A novel GWAS Atherosclerosis Locus Regulates Plasma CXCL12 levels", Gordon Conference on Atherosclerosis; Tilton NH

Jun, 2009 "Management of Cardiac Disease in Impaired Glucose Tolerance", Atlantic City Medical Center Medical Grand Rounds; Atlantic City, NJ

Oct, 2009 "Human Translational Studies of Inflammation, Insulin Resistance and Atherosclerosis", Cardiovascular Medicine Grand Rounds; Philadelphia PA

Oct, 2009 "Human Translational Studies of Inflammation, Psoriasis and Atherosclerosis", The Murdough Symposium on Psoriasis, Case Western University; Cleveland OH

Oct, 2009 "Psoriasis and Cardiovascular Care: An Innovative and Integrated Approach to Risk Stratification and Risk Reduction", Murdough Symposium on Psoriasis, Cleveland OH

Nov, 2009 "A novel GWAS Atherosclerosis Locus Regulates Plasma CXCL12 levels", American Heart Association' Orlando FL

Feb, 2010 "Human Translational Studies of CXCL12", Cardiovascular Institute, University of Pennsylvania, Philadelphia PA

Sep, 2010 "Convergence of CXCL12 and PHACTR-1: Novel GWAS Signals for MI", Northwestern Young Investigators Forum, Chicago, IL

Sep, 2010 "Cardiovascular Care of Patients with Psoriasis", Case Western University Murdough Symposium, Cleveland, OH

Oct, 2010 "Genomic Variation, Inflammation and Vascular Disease", Inflammation Symposium, University of Medicine and Dentistry of New Jersey, Newark, NJ

Nov, 2010 "Convergence of CXCL12 and PHACTR-1: Novel GWAS Signals for MI", Amaerican Heart Association Young Investigator Award Finalist, Chicago, IL

Mar, 2011 "Evidence Based Practice of Advanced Inflammatory and Lipoprotein Testing", American Occupational Medicine Conference, Washington, DC

Jun, 2011 "Detection of Subclinical Systemic and Vascular Inflammation in Psoriasis using FDG PET/CT", Division of Division of Allergy/Immunology, Rheumatology and Department of Dermatology (AIR) Grand Rounds, SUNY Rochester, Rochester, NY


Jun, 2011 "FDG PET/CT Detects Vascular Inflammation in Vivo in Psoriasis",

Updates in Dermatology, New York University Department of Dermatology, New York, NY

Jun, 2011 "In Vivo Modulation of CXCL12 in Adipose and Plasma", Gordon Conference on Atherosclerosis, Newport, RI

Sept, 2011 “Human Translational Studies of Inflammation and Cardiometabolic Diseases”, Lasker Scholar Seminar, National Institutes of Health

Oct, 2011 "Human Translational Studies of Inflammation and Atherosclerosis: From Epidemiology and Back", Johns Hopkins University Welch Center Grand Rounds, Baltimore, MD

Jul, 2012 “Psoriasis and Cardiovascular Risk”, Dermatology Resident Grand Rounds, National Navy Medical Center, Bethesda, MD

Sept, 2012 Oct, 2012 Oct, 2012 Jan, 2013

“Advanced Cardiometabolic Phenotyping in Psoriasis: Links between Psoriasis and CV Risk”, World Psoriasis Congress, Stockholm, Sweden “Understanding Psoriasis: Why a Cardiologist”, National Psoriasis Foundation, Bethesda Country Club, Bethesda, MD “Human Translational Studies of Inflammation and Cardiometabolic Diseases: From Epidemiology and Back”, Extramural NHLBI, Bethesda, MD “Inflammation and Cardiometabolic Diseases: Associative or Causal”, George Washington University CV Grand Rounds, Washington, DC


Jan, 2013

Jan, 2013 Jan, 2013 Jan, 2013 Feb, 2013 Mar, 2013 Mar, 2013 Mar, 2013 Apr, 2013 Apr, 2013 Jun, 2013 Jun, 2013 Jun, 2013 Jul, 2013

“Human Translation of Inflammation and Cardiovascular Disease”, George Washington University Grand Rounds, Washington, DC “Human Translational Studies of Inflammation and Cardiometabolic Diseases: In Vivo Studies and Beyond”, Weekly Inflammation and Immunity Seminar Series, Center for Cancer Research, Frederick, MD “Human Translational Studies of Inflammation and Cardiometabolic Disease”, Eli Lilly and Company, Indianapolis, IN “Human Translational Studies of Inflammation and Cardiometabolic Disease”, Novartis Pharmaceuticals Co., East Hanover, NJ “Human Translational Studies of Inflammation and Cardiometabolic Disease”, Johns Hopkins University Dermatology Grand Rounds, Baltimore, MD “A Comparison of Vascular Inflammation in Rheumatoid Arthritis, Psoriasis and Healthy Controls by FDG-PET/CT: A Pilot Study,” American College of Cardiology 62nd Annual Scientific Session, San Francisco, CA “Human Translational Studies of Inflammation and Cardiometabolic Disease”, University of Maryland Dermatology Grand Rounds, College Park, MD “Human Translational Studies of Inflammation and Cardiometabolic Disease”, Baylor University Dermatology Grand Rounds, Dallas, TX “Human Translational Studies of Inflammation and Cardiometabolic Disease”, George Washington University Nephrology Grand Rounds, Washington, DC “Human Translational Studies of Inflammation and Cardiometabolic Disease”, NEDS Didactic Symposium, University of Connecticut Health Center Department of Dermatology, Farmington, CT “Human Translational Studies of Inflammation and Cardiometabolic Disease”, Case Western University, Cleveland, OH “Human Translational Studies of Inflammation and Cardiometabolic Disease”, Cardiovascular Imaging Research Seminar, University of Pennsylvania, Philadelphia, PA “Psoriasis and Cardiometabolic Disease: Inflammation at the Heart of the Matter?”, Canadian Dermatology Association 2013 Annual Meeting, Toronto, CA “Human Translational Studies of Inflammation and Cardiometabolic Disease”, Visiting Professor, Northwestern University Department of Dermatology Grand Rounds, Chicago, IL


Jul, 2013

Jul, 2013 Sept, 2013 Oct, 2013 Nov, 2013 Feb, 2014 Feb, 2014 March, 2014 April, 2014 June, 2014 Oct, 2014 Oct, 2014 Oct, 2014 Nov, 2014 Dec, 2014

Keynote Speaker, NHLBI K Award Investigator’s Meeting, Bethesda, MD Persistent Inflammation and Immune Activation in HIV-Infected Children and Youth on Effective ART, NICHD Offices, NIH, Rockville, MD Pennsylvania Regional Occupational Medicine Meeting, Philadelphia, PA Androgen Excess Meeting, Newport, RI Key Note: “Inflammation and Cardiometabolic Diseases”, International Psoriasis Council, Boston, MA “Inflammation and Cardiometabolic Diseases: An Attempt to Dissect Causality and Association”, University of Michigan Grand Rounds, Ann Arbor, MI National Institute of Arthritis and Musculoskeletal and Skin Diseases Fellows talk "Impact of psoriasis severity on hypertension control: a population-based study in the United Kingdom", American Academy of Dermatology Meeting, Denver, CO “Inflammation and Cardiometabolic Diseases: An Attempt to Dissect Causality and Association”, University of Pittsburgh Medical Center Grand Rounds, Pittsburgh, PA “Incidence of Major Adverse Cardiovascular Events with Secukinumab: A Pooled Analysis of Data from Phase 2 and 3 Clinical Trials in Psoriasis”, Federation of Clinical Immunology Societies, Chicago, IL “Psoriasis, a systemic disease: What are the practical consequences?”, European Academy of Dermatology and Venereology, Amsterdam, Netherlands “Inflammation and Cardiometabolic Diseases”, Androgen Excess and PCOS Society Annual Meeting, Kauai, HI “Inflammation and Cardiovascular Disease” University of Hawaii Grand Rounds, Honolulu, HI “Human Translational Studies of Inflammation and Cardiometabolic Diseases” and “Psoriatic Diseases as a Human Model to Study Inflammatory Cardiometabolic Diseases,” Cleveland Clinic Grand Rounds, Cleveland, OH “In-vivo characterization of vascular diseases in psoriasis through implementation of a multi-modal imaging program”, 7th International Psoriasis: From Gene to Clinic Congress, London, UK


Jan, 2015 “Human Translational Studies of Inflammation and Cardiometabolic Disease”, Vanderbilt University Grand Rounds, Nashville, TN Apr, 2015 “Inflammation and Cardiometabolic Diseases: Translational Imaging”, Montefiore Medical Center Grand Rounds, Bronx, NY May, 2015 TBD, New York University, New York, NY July, 2015 TBD, National Psoriasis Foundation 2015 Research Symposium, San Francisco, CA July, 2015 “Cardiovascular Disease and Psoriasis” , 4th World Psoriasis and Psoriatic Arthritis Conference, Stockholm, Sweden Organizing Roles in Scientific Meetings: 2008 American College of Physicians Pennsylvania State Chapter

Executive Committee Harrisburg, PA

Nov, 2009 American Heart Association Council of Epidemiology and Prevention, Early Career Symposium Booth Orlando FL

2009 American Heart Association, Council on Epidemiology and Prevention 39th Annual Meeting, Early Career Annual Meeting Planning Committee Marlton, FL

Nov, 2010 Moderator, Early Career Committee Workshop, American Heart Association Scientific Sessions Chicago, IL

Mar, 2011 Moderator, Obesity and Cardiovascular Disease, American College of Cardiology Sessions New Orleans, LA

Nov, 2011 Moderator, Functional Genomics and Translational Biology (FGTB) of the American Heart Association Early Career Session Orlando, FL

2012 Organizing Member, American Heart Association NPAM/Epidemiology Annual Meeting Sessions 2012 TBD

Nov, 2012 Moderator, Early Career Session, American Heart Association Mar, 2013 Moderator, Traditional or New Risk Factors, NPAM/Epidemiology

Annual Scientific Sessions, New Orleans, LA Mar, 2013 Moderator, “Acute Coronary Syndromes: Basic II”, American

College of Cardiology 62nd Annual Scientific Sessions, San Francisco, CA

Bibliography: Research Publications, peer reviewed (print or other media): 1. Windsor J, Santoian EC, Tarazona N, Mehta NN, Malosky SA and Dennis CA: Local

and Systemic Steroids in a Swine Model of Arterial Injury. Journal of Investigative Medicine 43(2): 271-3, Apr 1995.


2. Ferrari VA, Mehta NN, Soulen M, Roberts DA, St John SM: Images in cardiovascular

medicine. Pulmonary venous aneurysms in hereditary hemorrhagic telangiectasia detected by 3-dimensional magnetic resonance angiography. Circulation 108(17): e122-3, Oct 2003. PMCID: PMC1470768

3. Mehta NN, Loria PM, Hobert O: A genetic screen for neurite outgrowth mutants in

Caenorhabditis elegans reveals a new function for the F-box ubiquitin ligase component LIN-23. Genetics 166(3): 1253-67, Mar 2004. PMCID: PMC1470768

4. Mehta, NN. Romanelli, J. Sutton, M, Graham St J.: Native aortic valve vegetative

endocarditis with Cunninghamella. European Journal of Echocardiography 5(2): 156-8, Mar 2004. PMCID: PMC1470768

5. Reilly MP, Wolfe ML, Rhodes T, Girman C, Mehta NN, Rader DJ: Measures of

insulin resistance add incremental value to the clinical diagnosis of metabolic syndrome in association with coronary atherosclerosis. Circulation 110(7): 803-9, Aug 2004. PMCID: PMC2218847

6. Mehta NN and Reilly MP. : Assessment of Cardiovascular Risk in the HAART-

Treated HIV-1 Population. HIV Clinical Trials 6(1): 5-24, Jan/Feb 2005. 7. Chokshi, R. Openshaw, J. Mehta, NN. Mohler, E 3rd.: Purple glove syndrome

following intravenous phenytoin administration. Vascular Medicine 12(1): 29-31, Feb 2007. PMCID: PMC2218847

8. Anderson PD, Mehta NN, Wolfe ML, Hinkle ChC, Pruscino L, Comiskey LL, Tabita-

Martinez J, Sellers KF, Rickels MR, Ahima RS, Reilly MP: Innate immunity modulates adipokines in humans. The Journal of clinical endocrinology and metabolism 92(6): 2272-9, Jun 2007. PMCID: PMC2218847

9. Nolan A, Weiden M, Kelly A, Hoshino Y, Hoshino S, Mehta NN, Gold JA: CD40 and

CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis. American journal of respiratory and critical care medicine 177(3): 301-8, Feb 2008. PMCID: PMC2218847

10. Qasim A, Mehta NN, Tadesse MG, Wolfe ML, Rhodes T, Girman C, Reilly MP:

Adipokines, insulin resistance, and coronary artery calcification. Journal of the American College of Cardiology 52(3): 231-6, Jul 2008. PMCID: PMC2712798

11. Mehta NN, Sheetz M, Price K, Comiskey L, Amrutia S, Iqbal N, Mohler ER,

Reilly MP: Selective PKC Beta Inhibition with Ruboxistaurin and Endothelial Function in Type-2 Diabetes Mellitus. Cardiovasc Drugs Ther 23(1): 17-24, Feb 2009. PMCID: 18949545


12. Mehta NN, Sheetz M, Price K, Comiskey L, Amrutia S, Iqbal N, Mohler ER, Reilly

MP: Selective PKC beta inhibition with ruboxistaurin and endothelial function in type-2 diabetes mellitus. Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 23(1): 17-24, Feb 2009. PMCID: PMC3088108

13. Martin SS, Qasim AN, Mehta NN, Wolfe M, Terembula K, Schwartz S, Iqbal N,

Schutta M, Bagheri R, Reilly MP: Apolipoprotein B but not LDL cholesterol is associated with coronary artery calcification in type 2 diabetic whites. Diabetes 58(8): 1887-92, Aug 2009. PMCID: PMC2712798

14. Shah R, Lu Y, Hinkle CC, McGillicuddy FC, Kim R, Hannenhalli S, Cappola TP,

Heffron S, Wang X, Mehta NN, Putt Mary, Reilly Muredach P: Gene profiling of human adipose tissue during evoked inflammation in vivo. Diabetes 58(10): 2211-9, Oct 2009. PMCID: PMC2750231

15. Mehta NN, McGillicuddy FC, Anderson PD, Hinkle CC, Shah R, Pruscino L, Tabita-

Martinez J, Sellers KF, Rickels MR, Reilly MP: Experimental endotoxemia induces adipose inflammation and insulin resistance in humans. Diabetes 59(1): 172-81, Jan 2010. PMCID: PMC2797919

16. Mehta NN, McGillicuddy F, Anderson P, Hinkle C, Shah R, Pruscino L, Tabita-

Martinez J, Sellers K, Rickels MR, Reilly MP : Experimental Endotoxemia Induces Adipose Inflammation and Insulin Resistance in Humans. Diabetes 59(1): S1-8, Jan 2010 Notes: Supplemental data. PMCID: 19794059

17. Eraso LH, Ginwala N, Qasim AN, Mehta NN, Dlugash R, Kapoor S, Schwartz S,

Schutta M, Iqbal N, Mohler ER, Reilly MP: Association of lower plasma fetuin-a levels with peripheral arterial disease in type 2 diabetes. Diabetes care 33(2): 408-10, Feb 2010. PMCID: PMC2809293

18. Qasim AN, Martin SS, Mehta NN, Wolfe ML, Park J, Schwartz S, Schutta M, Iqbal

Nayyar, Reilly MP: Lipoprotein(a) is strongly associated with coronary artery calcification in type-2 diabetic women. International journal of cardiology 150(1): 17-21, Mar 2010. PMCID: PMC2988112

19. Gelfand JM, Azfar RS, Mehta NN: Psoriasis and cardiovascular risk: strength

innumbers. Journal of Investigative Dermatology 130(4): 919-922, April 2010. 20. Mehta NN, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM: Patients with

severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the General Practice Research Database. European heart journal 31(8): 1000-6, Apr 2010. PMCID: PMC2894736


21. Bagheri R, Qasim AN, Mehta NN, Terembula K, Kapoor S, Braunstein S, Schutta M,

Iqbal N, Lehrke M, Reilly MP: Relation of plasma fatty acid binding proteins 4 and 5 with the metabolic syndrome, inflammation and coronary calcium in patients with type-2 diabetes mellitus. The American journal of cardiology 106(8): 1118-23, Oct 2010. PMCID: PMC3086062

22. Shen H, Bielak LF, Ferguson JF, Streeten EA, Yerges-Armstrong LM, Liu J, Post W,

O'Connell JR, Hixson JE, Kardia SL R, Sun YV, Jhun MA, Wang X, Mehta NN, Li M, Koller DL, Hakonarson H, Keating BJ, Rader DJ, Shuldiner AR, Peyser PA, Reilly MP, Mitchell BD: Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification. Arteriosclerosis, thrombosis, and vascular biology 30(12): 2648-54, Dec 2010. PMCID: PMC2988112

23. Qasim AN, Budharaju V, Mehta NN, St Clair C, Farouk S, Braunstein S, Schutta M,

Iqbal N, Rader DJ, Reilly MP: Gender differences in the association of C-reactive protein with coronary artery calcium in type-2 diabetes. Clinical endocrinology 74(1): 44-50, Jan 2011. PMCID: PMC3005137

24. Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney

JM, Knouff CW, Thompson JR, Horne BD, Stewart AFR, Assimes TL, Wild PS, Allayee H, Nitschke PL, Patel RS, Martinelli N, Girelli D, Quyyumi AA, Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S, Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ: Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Lancet 377(9763): 383-92, Jan 2011. PMCID: PMC3086062

25. Wade AN, Fedyna S, Mehta NN, St Clair C, Ginwala N, Krishna RK, Qasim AN,

Braunstein S, Iqbal N, Schutta MH, Reilly MP: Type 2 diabetes does not attenuate racial differences in coronary calcification. Diabetes research and clinical practice 91(1): 101-7, Jan 2011. PMCID: PMC3086062

26. Martin SS, Qasim AN, Wolfe M, St Clair C, Schwartz S, Iqbal N, Schutta M, Bagheri

R, Mehta NN, Rader DJ, Reilly MP: Comparison of high-density lipoprotein cholesterol to apolipoprotein A-I and A-II to predict coronary calcium and the effect of insulin resistance. The American journal of cardiology 107(3): 393-8, Feb 2011. PMCID: PMC3086062

27. Mehta NN, Krishnamoorthy P, Martin SS, St Clair C, Schwartz S, Iqbal N,

Braunstein S, Schutta M, Rader DJ, Reilly MP: Usefulness of insulin resistance estimation and the metabolic syndrome in predicting coronary atherosclerosis in type 2 diabetes mellitus. The American journal of cardiology 107(3): 406-11, Feb 2011. PMCID: PMC3040419


28. Mehta NN, Li M, William D, Khera AV, Derohannessian S, Qu L, Ferguson JF,

McLaughlin C, Shaikh LH, Shah R, Patel PN, Bradfield JP, He J, Stylianou IM, Hakonarson H, Rader DJ, Reilly MP: The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels. European heart journal 32(8): 963-71, Apr 2011. PMCID: PMC3076669

29. Beheshti M, Saboury B, Mehta NN, Torigian DA, Werner T, Mohler E, Wilensky R,

Newberg AB, Basu S, Langsteger W, Alavi A: Detection and global quantification of cardiovascular molecular calcification by fluoro18-fluoride positron emission tomography/computed tomography--a novel concept. Hellenic journal of nuclear medicine 14(2): 114-20, May-Aug 2011. PMCID: PMC3146037

30. Mehta NN, Yu Y, Saboury B, Foroughi N, Krishnamoorthy P, Raper A, Baer A,

Antigua J, Van Voorhees AS, Torigian DA, Alavi A, Gelfand JM: Systemic and Vascular Inflammation in Patients With Moderate to Severe Psoriasis as Measured by [18F]-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG-PET/CT): A Pilot Study. Archives of dermatology. 147(9): 1031-9, 2011 Sept. Notes: e pub ahead of print May 2011. PMCID: PMC3158301

31. Shah R, Hinkle CC, Ferguson JF, Mehta NN, Li M, Qu L, Lu Y, Putt ME, Ahima RS,

Reilly MP: Fractalkine is a novel human adipochemokine associated with type 2 diabetes. Diabetes 60(5): 1512-8, May 2011. PMCID: PMC3292325

32. Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB,

Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann H, Diemert P, Cupples AL, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE, Voight BF, Kuulaasma K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB, Demissie S, Proust C, König IR, Wichmann H-E, Reinhard W, Hoffmann MM, Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu LL, El Mokthari NE, Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W, Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H, Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T, Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JCM, Uitterlinden AG, Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP, O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L, Salomaa V, Munzel T, Ziegler A, Blankenberg S: A Genome-wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease. Circulation. Cardiovascular genetics 4(4): 403-12, May 2011. PMCID: PMC3157552


33. Hasan R, GN, Shah R, KD, Wilensky R, Mehta NN: Quantitative Angiography of

Coronary Artery Disease in South Asians Reveals Differences in Vessel Size and Disease Severity Compared to Caucasians. American Journal of Cardiovascular Diseases 1(1), Jun 2011 Notes: in press.

34. Mehta NN & Rader DJ: Imaging with Indocyanine Green: Light at the End of the

Catheter? Cell Metabolism Jul 2011 Notes: in press, accepted June 18th, 2011. 35. Beheshti M, Saboury B, Mehta NN, Torigian DT, Werner T, Mohler ER, Wilensky R,

Newberg A, Basu S, Langsteger W, Alavi A: Detection and Global Quantification of Cardiovascular Molecular Calcification by 18F-Fluoride PET/CT: A Novel Concept Hellenic Journal of Nuclear Medicine Aug 2011 Notes: in press, accepted June 15, 2011.

36. Mehta NN, Yu Y, Pinnelas R, Krishnamoorthy P, Shin DB, Troxel AB, Gelfand JM:

Attributable risk estimate of severe psoriasis on major cardiovascular events. The American journal of medicine 124(8): 775.e1-6, Aug 2011. PMCID: PMC3146037

37. Mehta NN, Yu Y, Pinnelas R, Krishnamoory PK, Shin DB, Troxel AB, Gelfand JM:

Attributable Risk Estimate of Psoriasis on Major Adverse Cardiovascular Events. American Journal of Medicine Aug 2011 Notes: in press August 2011, accepted May 20, 2011.

38. Kimball AB, Szapary P, Mrowietz U, Reich K, Langley RG, You Y, Hsu Yielding

NM, Rade DJ, Mehta NN: Underdiagnosis and undertreatment of cardiovascular risk factors in patients with moderate-to-severe psoriasis. Journal of the American Academy of Dermatology 67(1):76-85, Jul 2012. Notes: Epub ahead of print Oct 2011.

39. Kimball AB, Szapary P, Mrowietz U, Reich K, Langley RG, You Y, Hsu M-C,

Yeilding N, Rader DJ, Mehta NN: Underdiagnosis and undertreatment of cardiovascular risk factors in patients with moderate to severe psoriasis. Journal of the American Academy of Dermatology 67(1): 76-85, Oct 2011. PMCID: PMC3278499

40. Hasan RK, Ginwala NT, Shah RY, Kumbhani DJ, Wilensky RL, Mehta NN:

Quantitative angiography in South Asians reveals differences in vessel size and coronary artery disease severity compared to Caucasians. American journal of cardiovascular disease 1(1): 31-7, 2011. PMCID: PMC3253512

41. Langan SM, Seminara, NM, Shin, DB, Troxel A, Kimmel SE, Mehta NN, Margolis

DJ, and Gelfand JM. : Prevalence of metabolic syndrome in patients with psoriasis: A population-based study in the United Kingdom. Journal of Investigative Dermatology 132(3 Pt 1):556-62, Mar 2012. Notes: Epub ahead of print Nov 2011.


42. Ferguson JF, Hinkle CC, Mehta NN, Bagheri R, Derohannessian SL, Shah R,

Mucksavage MI, Bradfield JP, Hakonarson H, Wang X, Master SR, Rader DJ, Li M, Reilly MP: Translational studies of lipoprotein-associated phospholipase Aâ‚in inflammation and atherosclerosis. Journal of the American College of Cardiology 59(8): 764-72, Feb 2012. PMCID: PMC3285416

43. de la Llera MM, McGillicuddy FC, Hinkle CC, Byrne M, Joshi MR, Nguyen V,

Tabita-Martinez J, Wolfe ML, Badellino K, Pruscino L, Mehta NN, Asztalos BF, Reilly MP: Inflammation modulates human HDL composition and function in vivo. Atherosclerosis 222(2): 390-4, Jun 2012. Notes: Epub ahead of print Feb 2012. PMCID: PMC3361641

44. Langan SM, Seminara NM, Shin DB, Troxel AB, Kimmel SE, Mehta NN, Margolis

DJ, Gelfand JM: Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United Kingdom. The Journal of investigative dermatology 132(3 Pt 1): 556-62, Mar 2012. PMCID: PMC3278499

45. Mehta NN, Torigian DA, Gelfand JM, Saboury B, Alavi A: Quantification of

Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT). Journal of visualized experiments (63):e3777, May 2012.

46. Mehta NN, Heffron SP, Patel PN, Ferguson J, Shah RD, Hinkle CC, Krishnamoorthy

P, Shah R, Tabita-Martinez J, Terembula K, Master SR, Rickels MR, Reilly MP: A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial. Journal of Translational Medicine 10(1): 124, Jun 2012.

47. Mehta NN, Krishnamoorthy P, Yu Y, Khan O, Raper A, Van Voorhees A, Troxel

AB, Gelfand JM: The impact of psoriasis on 10-year Framingham risk. Journal of the American Academy of Dermatology 67(4):796-8, Oct 2012. Notes: Epub ahead of print Jun 2012.

48. Baker JF, Mehta NN, Baker DG, Toedter G, Shults J, Von Feldt JM, Leonard MB:

Vitamin D, Metabolic Dyslipidemia, and Metabolic Syndrome in Rheumatoid Arthritis. The American Journal of Medicine 125(10):1036.e9-1036.e15, Oct 2012. Notes: Epub ahead of print Jul 2012.

49. Gaieski DF, Goldman JD, Holtzman DL, Shoff WH, Shepherd SM, Mehta NN, Goyal

M: Algid malaria treated with early goal-directed therapy. The American Journal of Emergency Medicine 31(1):263.e5-263.e10, Jan 2013. Notes: Epub ahead of print Jul 2012.


50. Mehta NN, Li R, Krishnamoorthy P, Yu Y, Farver W, Rodrigues A, Raper A, Wilcox

M, Baer A, Derohannesian S, Wolfe M, Reilly MP, Rader DJ, Vanvoorhees A, Gelfand JM: Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis. Atherosclerosis 224(1):218-21, Sept 2012. Notes: Epub ahead of print Jul 2012.

51. Shah R, Hinkle CC, Haris L, Shah R, Mehta NN, Putt ME, Reilly MP: Adipose

Genes Down-Regulated During Experimental Endotoxemia Are Also Suppressed in Obesity. The Journal of clinical endocrinology and metabolism 97(11):E2152-9, Nov 2012. Notes: Epub ahead of print Aug 2012.

52. Mulvey CK., Ferguson JF., Tabita-Martinez J, Kong S, Shah RY., Patel PN., Master

SR., Usman MHU., Propert KJ., Shah R, Mehta NN., Reilly MP.: Peroxisome Proliferator–Activated Receptor-α Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia. J Am Heart Assoc 1(4):e002923, Aug 2012.

53. Mehta NN. Journal of Translational Medicine introduces a new section of

Cardiovascular, Metabolic and Lipoprotein Translation. J of Translational Medicine 10(1):203, Sept 2012. Epub Ahead.

54. Yu Y, Sheth N, Krishnamoorthy P, Saboury B, Raper A, Baer A, Ochotony R, Doveikis J, Derohannessian S, Voorhees AS, Torigian DA, Alavi A, Gelfand JM, Mehta NN. Aortic vascular inflammation in psoriasis is associated with HDL particle size and concentration: a pilot study. Am J Cardiovasc Dis 2(4):285-92, Oct 2012.

55. Ogdie A, Langan S, Love T, Haynes K, Shin D, Seminara N, Mehta NN, Troxel A,

Choi H, Gelfand JM. Prevalence and treatment patterns of psoriatic arthritis in the United Kingdom. Rheumatology (Oxford) Dec 2012. Epub Ahead.

56. Mehta NN. Large-scale association analysis provides insights into the genetic

architecture and pathophysiology of type 2 diabetes mellitus. Circ Cardiovasc Genet 5(6):708-10, Dec 2012.

57. Bose S, Krishnamoorthy P, Varanasi A, Nair J, Schutta M, Braunstein S, Iqbal N,

Schwartz S, Clair CS, Master SR, Rader DJ, Reilly MP, Mehta NN. Measurement of waist circumference predicts coronary atherosclerosis beyond plasma adipokines. Obesity 21(1):E118-23, Jan 2013.


58. Ferguson JF, Patel PN, Shah RY, Mulvey CK, Gadi R, Nijjar PS, Usman HM, Mehta NN, Shah R, Master SR, Propert KJ, Reilly MP. Race and gender variation in response to evoked inflammation. J Transl Med 11(1):63, Mar 2013. Epub ahead.

59. Ferguson JF, Matthews GJ, Townsend RR, Raj DS, Kanetsky PA, Budoff M, Fischer

MJ, Rosas SE, Kanthety R, Rahman M, Master SR, Qasim A, Li M, Mehta NN, Shen H, Mitchell BD, O’Connell JR, Shuldiner AR, Ho WK, Young R, Rasheed A, Danesh J, He J, Kusek JW, Ojo AO, Flack J, Go AS, Gadegbeku CA, Wright JT, Saleheen D, Feldman HI, Rader DJ, Foulkes AS, Reilly MP. Candidate Gene Association Study of Coronary Artery Calcification in Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort Study. J Am Coll Cardiol. S0735-1097(13)02075-5, May 2013.

60. Blomberg BA, Akers SR, Saboury B, Mehta NN, Cheng G, Torigian DA, Lim E, Del

Bello C, Werner TJ, Alavi A. Delayed time-point 18F-FDG PET CT imaging enhances assessment of atherosclerotic plaque inflammation. Nucl Med Commun. June 24, 2013 [Epub ahead of print].

61. Mulvey CK, McNeill AM, Girman CJ, Churchill TW, Terembula K, Ferguson JF, Shah R, Mehta NN, Qasim AN, Rickels MR, Reilly MP. Differential Associations of Oral Glucose Tolerance Test-Derived Measures of Insulin Sensitivity and Pancreatic Beta-Cell Function with Coronary Artery Calcification and Microalbuminuria in Type 2 Diabetes. Diabetes Care. 2013 Aug 15. [Epub ahead of print]

62. Mehta NN, Li K, Szapary P, Krueger J, Brodmerkel C. Modulation of

cardiometabolic pathways in skin and serum from patients with psoriasis. J Transl Med. 2013 Aug 22;11(1):194. [Epub ahead of print]

63. Rose S, Sheth N, Baker J, Ogdie A, Raper A, Saboury B, Werner TJ, Thomas P,

Vanvoorhees A, Alavi A, Torigian D, Gelfand J, Mehta NN. A comparison of vascular inflammation in psoriasis, rheumatoid arthritis, and healthy subjects by FDG-PET/CT: a pilot study. Am J Cardiovasc. 2013 [Epub ahead of print]

64.Yueng H, Takeshita J, Mehta NN, Kimmel SE, Ogdie A, Margolis DJ, Shin DB, Attor

R, Troxel AB, Gelfand JM. Psoriasis severity and the prevalence of major medical comorbity: a population-based study. JAMA Dermatol. 2013.

65. Ferguson JF, Mulvey CK, Patel PN, Shah RY, Doveikis J, Zhang W, Tabita-Martinez

J, Terembula K, Eiden M, Koulman A, Griffin JL, Mehta NN, Shah R, Propert KJ, Song WL, Reilly MP. Mol Nutr Food Res. 2013 Nov 5.

66. Mehta NN, Matthews GJ, Krishnamoorthy P, Shah R, McLaughlin C, Patel P, Budoff

M, Chen J, Wolman M, Go A, He J, Kanetsky PA, Master SR, Rader DJ, Raj D, Gadegbeku CA, Shah R, Shreiber M, Fischer MJ, Townsend RR, Kusek J,

http://www.ncbi.nlm.nih.gov/pubmed/23949560







Feldman HI, Foulkes AS, Reilly MP; the Chronic Renal Insufficiency Cohort

(CRIC) Study Investigators. Higher plasma CXCL12 levels predict incident myocardial infarction and death in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort study. Eur Heart J. 2013 Dec 4.

67. Li RC, Krishnamoorthy P, DerOhannessian S, Doveikis J, Wilcox M, Thomas P, Rader DJ, Reilly MP, Van Voorhees A, Gelfand JM, Mehta NN. Psoriasis is associated with decreased plasma adiponectin levels independently of cardiometabolic risk factors. Clin. Exp. Dematol. 2014 vol. 39(1) pp. 19-24.

68. Dave J, Ahlman M, Lockshin B, Mehta NN. Vascular inflammation in psoriasis

localizes to the arterial wall using a novel imaging technique. JAAD. E-pub ahead.

69. Roe A, Hillman J, Butts S, Smith M, Rader D, Playford M, Mehta NN, Dokras A.

Decreased cholesterol efflux capacity and atherogenic lipid profile in young women with PCOS. J. Clin. Endocrinol. Metab., 2014.

70. Mehta NN, Gelfand JM. High-density lipoprotein cholesterol function improves after

successful treatment of psoriasis: a step forward in the right direction. J. Invest. Dermatol., 2014. Vol. 134(3) pp. 592-5.

71. Ferguson JF, Mulvey CK, Patel PN, Shah RY, Doveikis J, Zhang W, Tabita-Martinez

J, Terembula K, Eiden M, Koulman A, Griffin JL, Mehta NN, Shah R, Propert KJ, Song WL, Reilly MP. Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers. Mol. Nutr. Food. Res. 2014. Mar, 58(3) 601-3.

72. Dominic EA, Ramezani A, Anker SD, Verma M, Mehta N, Rao M. Mitochondrial

cytopathies and cardiovascular disease. Heart. 2014 Jan 21. 73. Takeshita J, Mohler ER, Krishnamoorthy P, Moore J, Rogers WT, Zhang L, Gelfand

JM, Mehta NN. Endothelial cell-, platelet-, and monocyte/macrophage-derived microparticles are elevated in psoriasis beyond cardiometabolic risk factors. J Am Heart Assoc. 2014 Feb 28; 3(1).

74. Mehta N, Qamar A, Qu L, Qasim AN, Mehta NN, Reilly MP, Rader DJ. Differential association of plasma angiopoitin-like proteins 3 and 4 with lipid and metabolic traits. Arterioscler Thromb Vasc Biol. 2014 May; 34(5).

75. Mehta NN, Dagur PK, Rose SM, Naik HB, Stansky E, Doveikis J, Biancotto A,

Playford MP, McCoy JP Jr. IL-17A production in human psoriatic blood and


lesions by CD146+ T cells. J Invest Dermatol. 2014 July 24.

76. Subramanain S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG,

Cheng S, Wang TJ, Mehta NN, Levy D. Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk. Arterioscler Thromb Vasc Biol. 2014 Jul 24.

77. Rose S, Dave’ J, Millo C, Naik HB, Siegel EL, Mehta NN. Psoriatic arthritis and sacroiliitis are associated with increased vascular inflammation by 18fluorodeoxyglucose positron emission tomography computed tomography: baseline report from the Psoriasis Atherosclerosis and Cardiometabolic Disease Initiative. Arthritis Res Ther. 2014 Jul 30; 16(4):R161 [Epub ahead of print].

78. Shlyankevich J, Mehta NN, Krueger JG, Strober B, Gudjonsson JE, Qureshi AA,

Tebbey PW, Kimball AB. Accumulating evidence for the association and shared pathogenic mechanisms between psoriasis and cardiovascular-related comorbidities. Am J Med. 2014 Dec; 127(12): 1148-1153.

79. Rose S, Stansky E, Dagur PK, Samsel L, Weiner E, Jahanshad A, Doveikis J, Naik

HB, Playford MP, McCoy J, Mehta NN. Characterization of immune cells in psoriatic adipose tissue. J Transl Med. 2014 Sep 16: 12(1): 258.

80. Takeshita J, Wang S, Shin DB, Mehta NN, Kimmel SE, Margolis DJ, Troxel AB,

Gelfand JM. Effect of psoriasis severity on hypertension control: a population-based study in the United Kingdom. JAMA Dermatol. 2014 Oct 15.

81. Ogdie A, Yu Y, Haynes K, Love TJ, Maliha S, Jiang Y, Troxel AB, Hennessy S,

Kimmel SE, Margolis DJ, Choi H, Mehta NN, Gelfand JM. Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a population-based cohort study. Ann Rheum Dis. 2014 Oct 28.

82. Khera AV, Mehta NN. Single-cell transcriptomics: an emerging tool in the study of

cardiometabolic disease. J Transl Med. 2014 Nov 6: 12(1):312. 83. Munger A, Chow D, Playford M, Parikh N, Gangcuanco LM, Nakamoto B,

Kallianpur K, Ndhlovu L, Shikuma C, Mehta N. Characterization of lipid composition and high-density lipoprotein (HDL) function in HIV-infected individuals on stable antiretroviral regimens. AIDS Res Hum Retroviruses. 2014 Nov 21.

84. Parikh NI, Gershenson M, Bennett K, Gangcuangco LM, Lopez MS, Mehta NN,

Playford MP, Nakamoto BK, Seto TB, Chow, DC, Shikuma CM. Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort. Atherosclerosis. 2014 Dec 20; 239(1): 50-54.


85. Ferguson JF, Shah RY, Shah R, Mehta NN, Rickels MR, Reilly MP. Activation of innate immunity modulates insulin sensitivity, glucose effectiveness and pancreatic β-cell function in both African ancestry and European ancestry healthy humans. Metabolism. 2014 Dec 26.

86. Liao KP, Playford MP, Frits M, Coblyn JS, Inannaccone C, Weinblatt ME, Shadick

NS, Mehta NN. The association between defuction in inflammation and changes in lipoprotein levels and HDL cholesterol efflux capacity in rheumatoid arthritis. J Am Heart Assoc. 2015 Jan 30; 4(2).

87. Zidar DA, Juchnowski S, Ferrari B, Clagett B, Pilch-Cooper HA, Rose S, Rodriguez

B, McComsey GA, Sieg SF, Mehta NN, Lederman MM, Funderburg NT. Oxidized LDL levels are increased in HIV infection and may drive monocyte activation. J Acquir Immune Defic Syndr. 2015 Feb 2.

Research Publications, peer-reviewed reviews: 1. Mehta NN, Reilly M: Atherosclerotic cardiovascular disease risk in the HAART-treated HIV-1 population. HIV clinical trials 6(1): 5-24, Jan-Feb 2005. PMCID: PMC2218847 2. Mehta NN, and Reilly MP.: Mechanisms and Components of the Metabolic Syndromes. Drug Discovery Today: Disease Mechanisms. 1(1): 1-16, Mar 2005.

3. Shah A, Mehta NN, Reilly MP: Adipose inflammation, insulin resistance, and

cardiovascular disease. JPEN. Journal of parenteral and enteral nutrition 32(6): 638-44, Nov-Dec 2008. PMCID: PMC2712798

4. Gelfand JM, Azfar RS, Mehta NN: Psoriasis and cardiovascular risk: strength in

numbers. The Journal of investigative dermatology 130(4): 919-22, Apr 2010. PMCID: PMC2866113

5. Farouk SS, Rader DJ, Reilly MP, Mehta NN: CXCL12: a new player in coronary

disease identified through human genetics. Trends in cardiovascular medicine 20(6): 204-9, Aug 2010. PMCID: PMC3235407

6. Gelfand JM, Mehta NN, Langan SM: Psoriasis and Cardiovascular Risk: Strength in

Numbers, Part II. The Journal of investigative dermatology 131(5): 1007-10, May 2011. PMCID: PMC3292325

7. Mehta NN: Large-scale association analysis identifies 13 new susceptibility Loci for

coronary artery disease. Circulation. Cardiovascular genetics 4(3): 327-9, Jun 2011. PMCID: PMC3125595


8. Mehta NN, Rader DJ: Fluorescent green plaques: light at the end of the catheter? Cell

metabolism 14(1): 7-8, Jul 2011. PMCID: PMC3138117 9. Mehta NN: A genome-wide association study in europeans and South asians identifies

5 new Loci for coronary artery disease. Circulation. Cardiovascular genetics 4(4): 465-6, Aug 2011. PMCID: PMC3190399

10. Mehta NN: Large-scale gene-centric analysis identifies novel variants for coronary

artery disease. PLoS genetics 7(9): e1002260, Sep 2011. PMCID: PMC3178591 11. Mehta, NN.: A GWAS of South Asians and Europeans Detects Five Novel CAD

Loci. Circulation. Cardiovascular Genetics in press: accepted 7/6/11, September 2011.

12. Farouk S, Rader DJ, Reilly MP, Mehta NN: CXCL12: A New Player in Coronary

Disease Identified through Human Genetics Trends in Cardiovascular Medicine 2011 Notes: in press.

13. Mehta NN: The effect of chromosome 9p21 variants on cardiovascular disease may

be modified by dietary intake. Circulation. Cardiovascular genetics 5(1): 148-50, 2012 Feb 1. PMCID: PMC3285416

14. Mehta NN, Reilly Muredach P: Monocyte mayhem: do subtypes modulate distinct

atherosclerosis phenotypes? Circulation. Cardiovascular genetics 5(1): 7-9, 2012 Feb 1. PMCID: PMC3285416

Research Publications, non-peer reviewed: 1. Mehta, NN.: Novel Risk Factors and Primary Prevention of Coronary Artery Disease.

Hospital Physician Page: 1-9, Aug 2006. Abstracts: 1. Mehta, NN, Schutta, M, Wolfe, ML, Iqbal, N, Kimmel, SE, Rader, DJ, Reilly, MP:

Plasma adiponectin levels, cardiovascular risk factors, and coronary atherosclerosis in type 2 diabetes. Arteriosclerosis Thrombosis And Vascular Biology 24(5): P243, May 2004.

2. Reilly MP, Wolfe M, Rhodes T, Girman C, Mehta NN, Rader DJ.: Measures of Insulin

Resistance Add Incremental Value to the NCEP Metabolic Syndrome Criteria in the Association with Coronary Artery Calcification. Circulation 110(7), Aug 2004.

3. Anderson, PD, Mehta, NN, Wolfe, ML, McMahon, K, Hinkle, C, Comiskey, L,

Tabita-Martinez, J, Sellers, K, Ahima, BS, Rader, DJ, Reilly, MP: Adipokines in human endotoxemia. Journal Of Investigative Medicine 53(2): S388, Mar 2005.


4. Mehta, NN, Anderson, PD, Wolfe, M, Rickels, M, Zemel, B, Hinkle, C, Comiskey,

L, Tabita-Martinez, J, Ahima, R, Rader, DJ, Reilly, MP: Adiposity and pro-atherosclerotic responses to innate immune challenge in humans. Journal Of Investigative Medicine 53(2): S391, Mar 2005.

5. Anderson, P, Mehta, NN, Wolfe, ML, Hinkle, CC, Tabita-Martinez, JJ, Sellers, KF,

Rader, DJ, Reilly, MP: Atherogenic changes in apo-B lipoproteins during human inflammation. Circulation 112(17 Suppl. S): 1215 Oct 2005.

6. Anderson, PD, Mehta, NN, Wolfe, ML, McMahon, KE, Hinkle, CC, Comiskey, L,

Tabita-Martinez, JJ, Sellers, KF, Ahima, RS, Rader, DJ, Reilly, MP: Pathophysiology of insulin resistance in human inflammation. Circulation 112(17 Suppl. S): 3821, Oct 2005.

7. Anderson, P.A., Mehta, N., wolfe, M.L., McMahon, K., Hinkle, C., Comiskey, L.,

Tanbita-Marinez, J., Sellers, K., Ahima, R. S., Rader, D.J., Reilly, M.P.: Pathophysiology of insulin resistance in human inflammations. Circulation 112(II): 827, 2005.

8. Mehta, NN, Anderson, P, Wolfe, M, Rickels, M, Zemel, B, Hinkle, C, Tabita-

Martinez, J, Ahima, R, Sellers, K, Rader, DJ, Reilly, MP: Adiposity and atherogenic inflammatory response to endotoxin in humans. Journal Of The American College Of Cardiology 47(4 Suppl. A): 308A, Feb 2006.

9. Mehta, NN, Anderson, PD, Hinkle, C, Tabita-Martinez, J, Rickels, MR, Reilly, MP:

Modulation of the insulin signaling pathway in human inflammation. Arteriosclerosis Thrombosis And Vascular Biology 26(5): E49, May 2006.

10. Mehta, Nehal N, Mohler, Emile R, III, Amrutia, Shirsh, Reilly, Muredach P:

Abstract 3923: The Effect of Selective PKC-Inhibitor Ruboxistaurin on Endothelial Function and Oxidant Stress in Patients with Type 2 Diabetes Mellitus. Circulation 114: II_843-c- 2006.

11. de la Llera-Moya, Margarita, Pruscino, Leticia, Wolfe, Megan L, Nguyen, Vihn,

Mehta, Nehal, Reilly, Muredach P: Abstract 670: Serum Amyloid A May Attenuate the Loss of HDL Efflux Capacity During Human Endotoxemia. Circulation 114: II_112-b- 2006.

12. Heffron, SP, Mehta, NN, de la Llera-Moya, M, Pruscino, L, Tabita-Martinez, J,

Wolfe, M, Badelino, K, Rader, DJ, Reilly, MP: Degree of acute phase response predicts extent of HDL remodeling in human inflammation. Arteriosclerosis Thrombosis And Vascular Biology 27(6): E68, Jun 2007.


13. Heffron, SP, Mehta, NN, de la Llera-Moya, M, Terembula, K, Hinkle, C, Wolfe,

M, Reilly, MP: Abstract 1097: Very-low Dose Endotoxemia Induces High Density Lipoprotein Remodeling and Reduces Cholesterol Efflux in the Absence of a Clinical Inflammatory Response. Circulation 116: II_220-a- 2007.

14. Mehta, NN, Heffron, SP, Rickels, MR, Terembula, K, Ginwala, NT, Hinkle, C,

Wolfe, ML, Rader, DJ, Reilly, MP: Abstract 3593: Very-low Dose Endotoxemia Induces Insulin Resistance in the Absence of Clinical Inflammatory Responses. Circulation 116: II_814- 2007.

15. Varanasi, A, Mehta, NN, Hinkle, C, Udupa, J, Ginwala, NT, Reilly, MP:

Relationship between visceral adiposity, inflammatory markers, and insulin resistance following human endotoxemia. Arteriosclerosis Thrombosis And Vascular Biology 28(6): P507, Jun 2008.

16. Qasim, AN, Martin, SS, Mehta, NN, Rader, D, Reilly, MP: Abstract 3210: Lp(a) is

Strongly Associated with Coronary Artery Calcification in Type 2 Diabetic Women. Circulation 118: S_1113-c- 2008.

17. Mehta NN, William D, Khera A, Edmondson , Qasim A, Restine S, Pruscino L,

Hinkle C, He J, Stylianou I, Li M, Rader DJ, Reilly MP: A Novel GWAS Atherosclerosis Locus Regulates Plasma Levels of CXCL12. Gordon Conference Journal June 2009.

18. Mehta NN, Li M, Epstein S, Keating B, Hakonarson H, Rader DJ, Reilly MP.: The

ITMAT/Broad/CARE (IBC) Candidate Gene Array Identifies Novel Type 2 Diabetes Gene Associations with Coronary Artery Disease: The GRAND-CAD Consortium. American Society of Human Genetics Nov 2009 Notes: (presentation American Society of Human Genetics, 2008).

19. Martin SS, Rader DJ, Mehta NN, Wolfe M, Terembula K, Schwartz S, Iqbal N,

Schutta M, Bagheri R, Reilly MP, Qasim AN: Abstract 1618: High-Density Lipoprotein Cholesterol but Not Apolipoprotein A-I or -II is Associated With Coronary Calcium in Type 2 Diabetes. Circulation 120(18_MeetingAbstracts): S531- 2009.

20. Mehta, NN, Azfar, RS, Shin, DB, Neimann, AL, Troxel, AB, Gelfand, JM:

Abstract 1640: Patients With Severe Psoriasis and No History of Cardiovascular Disease Are at Increased Risk of Cardiovascular Mortality. Circulation 120: S536-b- 2009.

21. Mehta, NN, William, D, Pruscino, L, Khera, A, Edmondson, A, Qasim, A,

Restine, S, Hinkle, C, He, J, Stylianou, I, Li, M, Rader, DJ, Reilly, MP: Abstract 2077: A Novel GWAS Atherosclerosis Locus Regulates Plasma Levels of CXCL12. Circulation 120: S589-a- 2009.


22. Varanasi, A, Bose, S, Udupa, J, Duglash, R, Chandrupatla, H, Iqbal, N, Schutta,

M, Reilly, MP, Mehta, NN: Abstract 1623: Quantification of Visceral Adipose Tissue Adds Value to BMI and Metabolic Syndrome in Prediction of Subclinical Atherosclerosis in Men With Type 2 Diabetes. Circulation 120: S532- 2009.

23. Ferguson J, William D, Wang X, Qu L, Mehta NN, Reilly MP: Genetic variation in

CRP and PLA2G7 has differential associations with subclinical coronary atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2010.

24. Eraso LH, Ferguson J, Mehta NN, Li M, Keating B, Mohler III ER, Reilly MP:

Candidate Gene Association Study of Peripheral Arterial Disease in Type 2 Diabetes. Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2010.

25. Mehta, NN, Reilly, M, Rader, D, Mohler, E, VanVoorhees, A, Gelfand, J: Abstract

P040: Advanced cardiometabolic phenotyping in psoriasis links between psoriasis and cardiovascular disease? 3rd World Psoriasis & Psoriatic Arthritis Conference 2012.

26. Mehta NN, Matthews G, Budoff M, Chen J, Glenn M, Go A, He J, Kanetsky P,

Master S, Rader DJ, Raj D, Shah R, Screiber M, Fischer M, Townsend R, Kusek J, Feldman H, Foulkes A, Reilly MP: Higher Plasma CXCL12 Levels Predict Incident Cardiovascular Disease Events: Findings from the Chronic Renal Insufficiency Cohort Study. American Heart Association Scientific Sessions 2012.

27. Sheth N, Baker J, Ogdie A, Roper A, Saboury B, Werner T, Thomas P, Van Voorhees A, Alavi A, Torigian D, Gelfand J, Mehta NN: A Comparison of Vascular Inflammation in Rheumatoid Arthritis, Psoriasis and Healthy Controls by FDG-PET/CT: A pilot Study. American College of Cardiology Annual Meeting 2013.

28. Mehta NN, Dagur PK, Stansky S, Rose S, Biancotto A, Sonti K, Playford M, McCoy J.P.: CD146 expression identifies Th17 and Tc17 subsets in psoriatic blood and skin. International Investigative Dermatology Conference 2013.

29. Rose S, Sonti K, Dagur P, Lee P, Playford M, Celi F, Mehta NN: Characterization of adipose tissue inflammation may link psoriasis and cardiometabolic disease. International Investigative Dermatology Conference 2013.

30. Sheth, NH, Baker J, Ogdie A, Roper A, Saboury B, Van Voorhees A, Alavi A, Torigian D, Gelfand J, Mehta NN: The Use of FDG-PET/CT to Evaluate Vascular Inflammation in Inflammatory Diseases Compared to Healthy Controls: A Pilot Study. SNMMI Annual Meeting 2013.


31. Takeshita J, Saboury B, Salavati A, Torigian DA, Van Voorhees A, Mehta NN,

Alavi A, Gelfand JM: 18-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG PET-CT) as a Novel Tool for Quantification of Psoriasis Disease Activity: Proof of Concept from the Vascular Inflammation in Psoriais (VIP) Trial. Journal of Investigative Dermatology. 133(1): S177, May 2013.

32. Krishnamoorthy P, Rader DJ, Reilly M, Mehta NN: Advanced Lipid Testing Predicts Subclinical Atherosclerosis in Low Risk Population Beyond Traditional Risk Factors. International Academy of Cardiology 2013.

33. Griffiths C, Reich K, Leonardi C, Blauvelt A, Mehta NN, Tsai T-F, Gong Y, Huang

J, Fox: Secukinumab Demonstrates an Acceptable Safety Profile in Moderate to Severe Plaque Psoriasis: Pooled Analysis of 10 Phase 2/3 Studies. European Academy of Dermatology and Venereology Congress 2014 Late Breaking Abstract.

34. Salahuddin T, Natarajan B, Selwaness M, Sadek A, Playford M, Doveikis J,

Bleumke D, Mehta NN: Reduced High-Density Lipoprotein Efflux in Psoriasis Relates to Increased Coronary Plaque Burden by Quantitative CT Angiography. American Heart Association EPI/Lifestyle 2015 Scientific Sessions 2015.

35. Natarajan B, Salahuddin T, Sadek H, Nanda N, Playford M, Doveikis J, Hirscovitch

P, Mehta NN: Insulin Resistance Determines Severity of Vascular Inflammation by 18-Fluorodeoxy Glucose PET-CT in Psoriasis. American Heart Association EPI/Lifestyle 2015 Scientific Sessions 2015.

36. Powell-Wiley T, Krishnamoorthy P, Natarajan B, Playford M, Doveikis J, Ng Q,

Yao J, Mehta NN: Directly Quantified Visceral Adipose Tissue Predicts Vascular Inflammation Beyond Traditional Anthropometric Measures. American Heart Association EPI/Lifestyle 2015 Scientific Sessions 2015.

Books: 1. Christopher P. Cannon, MD and Nehal N. Mehta, MD, FACP: Contemporary

Guide to Cardiovascular Therapy. (First Edition), July 2008 Notes: ISBN 9781931981880.

2. Stephen Pan, MD, MS, Juyong Brian Kim, MD, MPH, Nehal N. Mehta, MD, MSCE, FAHA, Joshua W. Knowles, MD, PhD, FAHA, FACC: “Genetic Applications in Coronary Artery Disease,” in Cardiovascular Genetics and Genomics in Clinical Practice. 2014.

nehal n. mehta, md, msce, faha page 1 nehal n. mehta, md ... … · 2006 american college of...

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