NATIONAL UNIVERSITY OF PHARMACYDiscipline «Pharmaceutical and medical merchandizing»

Department of Commodity Science

Goods of the limited pharmaceutical range

The commodities of a limit pharm assortment commodities are considered,

which specific weight in commodity turnover of pharmaceutical institutions very

it is small and makes no more than 1-2%.

At the same time they are necessary goods for the population,

treatment-and-prophylactic establishments, sanitary and epidemiologic

stations, control and analytical laboratories and others/

To these commodities behave:

Mineral waters

DetergentsCosmetic medical

preparations

Leeches medical and others

Disinfection and disinsection

meansChemical reagents

Mineral waters-these are the natural or artificial waters containing raised

quantity of mineral or organic substances and possessing specific physical and chemical properties,

which are used in the treatment-and-prophylactic purposes

The presence of biologically-active substances determines themcurative using for many diseases:

Gastrointestinal tract Buds

Cardiovascular system

At violation of exchange substances

Cardiovascular system

Livers

Classification of mineral waters

By origin

the natural

The artificial

on a mineralization (to the general to the contents

salts, g/l)

Low-mineralized (to 2 g/l)

onchemical

to composition

Low-mineralized (2-5 g/l)

Average mineralization (5-15 g/l)

chloride

hydrocarbonate (the carbonic)

sulphatic

mixed

Brine (35-150 g/l)

on maintenance salts and gases

Alkaline waters

Sulphureous watersLime or earthy waters

Waters of table salt

Iron waters

bitter waters

Chemically indifferent warm sources

Highly mineralized (15-35 g/l)

nitrate

waters of difficult structure

Classification of mineral waters

On application

Outward application

On a temperature source

Cold (to t 20 C)

The subthermal (t 20 - 37 ) C)

Thermal (t 37-42 ) C)

On treatment-and-prophylactic action

Medical (mineralization of 8-12 g/l)

Medical and dining rooms (mineralization of 2-8 g/l)

Dining rooms (mineralization of 1-2 g/l)

Internal consumption

The hyper thermal (t of over 42 2 C)

Ассортимент и применение минеральных водАссортимент и применение минеральных вод

Name of waterName of water CountryCountry Mineralization

g/l

Activity ApplicationApplication

Berezivska UkraineUkraine 0,80,8 Regulates a gastroenteric Regulates a gastroenteric secretion, increases a diuresis secretion, increases a diuresis

and strengthens a and strengthens a hematogenesis.hematogenesis.

Treatment of Treatment of gastrointestinal tract gastrointestinal tract and urinoexcretory and urinoexcretory

waysways

МиргородскаяМиргородская --||----||-- 2,82,8 Influences secretion and acidity Influences secretion and acidity of gastric juice, increases bile of gastric juice, increases bile

allocation, improves a allocation, improves a metabolism.metabolism.

Treatment of the Treatment of the digestive system, is digestive system, is inflammation of gall-inflammation of gall-bladder, metabolic bladder, metabolic

diseases.diseases.

NaftusyaNaftusya --||----||-- 0,80,8 Increases a diuresis, diminishes Increases a diuresis, diminishes inflammatory processes, inflammatory processes,

diuretic and selection of bile, diuretic and selection of bile, accelerates oxidizing accelerates oxidizing

processes.processes.

Treatment of urological Treatment of urological diseases, inflammations diseases, inflammations

of a gall bladder, of a gall bladder, hepatitises.hepatitises.

SvalavaSvalava --||----||-- 9,79,7 Influences on a gastric Influences on a gastric secretion and acidity, dilutes secretion and acidity, dilutes

mucus, strengthens the mucus, strengthens the leadingout of urinary sand.leadingout of urinary sand.

Treatment of Treatment of gastrointestinal tract, gastrointestinal tract, urinoexcretory ways, urinoexcretory ways,

liver, metabolic liver, metabolic disturbances.disturbances.

Ассортимент и применение минеральных водАссортимент и применение минеральных вод

Name of waterName of water CountryCountry Mineralization g/l

Activity ApplicationApplication

TruskavetskayaTruskavetskaya UkraineUkraine 1,21,2 Regulates a gastroenteric Regulates a gastroenteric secretion, increases a secretion, increases a

diuresis and strengthens a diuresis and strengthens a hematogenesis.hematogenesis.

Treatment of gastrointestinal Treatment of gastrointestinal tract, operated concerning tract, operated concerning ulcerous illness, catarrhs ulcerous illness, catarrhs

and gastric ulcers.and gastric ulcers.

NarzanNarzan RussianRussian 2,32,3 Strengthens an intestines Strengthens an intestines vermicular movement, vermicular movement, promotes dissolution of promotes dissolution of

phosphates.phosphates.

Treatment of catarrhs of Treatment of catarrhs of stomach, urinary and stomach, urinary and

respiratory ways, organs of respiratory ways, organs of circulation of blood.circulation of blood.

EssentukiEssentuki

№№4 и №174 и №17

--||----||-- 8,3; 8,3; 11,311,3

Favourably influences on Favourably influences on the flow of exchange the flow of exchange

processes.processes.

Treatment of gastrointestinal Treatment of gastrointestinal tract, liver, gall-bladder and tract, liver, gall-bladder and urinoexcretory ways, gout urinoexcretory ways, gout

and diabetes.and diabetes.

BorjomiBorjomi GeorgiaGeorgia 66 Like the action " of Like the action " of ««SvalavaSvalava».».

Like the action " of Like the action " of ««SvalavaSvalava».».

Requirements to the mineral waters, poured out in bottles

For preservation of chemical properties and flavoring qualities water has to be saturated carbonic acid.

Bottles have to be hermetically corked

Water has to be colourless, transparent, without a foreign smell and taste

(except characteristic for this water).

For ferruterous waters it is allowed poorly the expressed yellowish shade

For some waters the insignificant deposit of mineral salts that makes a reservation the standard on this water is assumed

Packing of mineral waters

Glass bottles Bottles from РЕТ Packing "Tetra-Pak"

0,33; 0,5 l

and other0,33 – 2,5 l

0,1 – 1 l

Crown caps(tin covers) and

screw covers with the natural (cortical) or

polymeric laying.

Polyethylene corks

or lids with a break ring.Heat sealing

Corking Corking Corking

MarkingMarking

Each unit of a retail container with mineral water is marked by a label, and on packing "Tetra-Pak" marking is put directly on packing

whom have to be specified in Ukrainian:

–name of the enterprise of the manufacturer, his address and trademark;– name of water and its group;– mineralization, g/l;– chemical composition, mg/l (for medical table waters)– setting of water(table, curatively-table);– recommendations on curative application;– suitability term to the use;– date of overflow;– capacity, l;– terms of storage;– stroke-code of products;– standard designation;– sign of accordance (for the certificated products).

Storage of mineral waters

Store bottles with mineral water in horizontal situation

in boxes or stacks to 18 rows in dry aired rooms

at a temperature from 5 to 20 of 0C.

Production in capacities from RET and packing "Tetra-Pak"

it is stacked in the vertical situation no more than 5 ranks high.

Warranty period of storage – 1 year, for ferruterous waters – 4 months.

Portage of mineral waters

Mineral waters transport all types of transportin accordance with the rules of portage perishable

loads operating on this type of transport.During loading, portages and

unloading protect products from atmospheric fallouts.

Disinfectants

it is the chemicals applied for

eliminations(disinfestations)

morbific microorganisms on ways

their transition from the source of infection to the organism.

These substances are called as disinfectants..

Disinfection are exposed all products or materials participating in medical and diagnostic process,

and also rooms and medical equipment.

Classification of methods and means of disinfection

The mechanical

cleaning

damp cleaning

The physical

the thermal (high and low temperature, water vapor, drying, boiling, burning)

The chemical

radiation(direct sunshine, UF, X-ray, etc.)

ultrasound(for preparation of vaccines)

chlorine and hloraktivny connectionsiodine, bromine and their connections

Surfaceactive substances

washing

washable

airing

Chemicals in the form of gases and water solutions

acids, peracids and their saltslyesalcoholsphenols and

theirderivativessalts of heavy metals

Requirements to disinfecting solutions

Good solubility in water

Stability to light and to oxygen of air

Harmlessness for the person and animals

Lack of an unpleasant smell and damaging

actions on materials

Good wettability

Reliable and fast action on all pathogenic microorganisms

Classification of chemical disinfectants

Means of the rough strong disinfection

strongly muddy materials

Means of the thin soft disinfection

skin

Means of the chemical disinfection

surgical instruments

air in the closed rooms

to the shoe

to furniture

articles of care of patients

toiletsinsignificantly muddy linen

to furniture

equipments

lighting devices

Basic assortment of some Basic assortment of some chemical disinfectantschemical disinfectants

Hydrogen peroxide,

3% solution

Alcohol ethyl,

70% solution

Chloric lime

Neochlorine

Sterilium

Chloroaminum B

Lizoformin "Asepsises - Spetsial"

Aerodezin 2000

Chlorcin

Disinsection means

these are the chemicals applied to destruction of arthropods,

the insects carrying infectious diseases

(pincers, flies, mosquitoes, mosquitoes, cockroaches, housing ants, etc.).

These substances are called as insecticides.

Classification of insecticides in dependence of their penetration into an organism

The intestinal(through

the digestive system)

The contact(through

the external covers)

Fumigants(through

respiratory ways)

Range of disinsection means

On the basis oforganophosphorus

compounds

dichlophos

On the basis ofdimetildichlor-

venylphosfatas DDVF

«Neophos»

On the basisdiethyltoluamide

and dimetilphthalates 

(DMF)

(repellents)

carbophos

Vofotox SP18

Chlorophos and etc.

dophlox

«Nephrafos»

«Dichlophos»

«Molemor»

«Carbosol»

«Desmol»

«Rapthor»

«Zansarin»

«Anthikus»

«Rebeftal»

Rephtamid»

Maximal efficiency at minimum

norms of expense of preparation

Efficiency preservationunder the influence of factors

environment

Rather fastdecomposition in water

and the soil with education safe substances

The minimum negative impact on the person

and animals

Absence unpleasant smell and damaging operating on materials

Sufficient safety at storage, eliminating

possibility of poisoningauxiliary personnel

Main requirements to insecticides

Packing of disinfectants

PACK

drums for 25, 50, 100 l

glass large bottles on 20 – 40 l

polyethylene tanks and bulbs

to 50 л

barrels from 50 to 275 l

Capacities close hermetically jams, wax, wrap up a polyvinylchloride film

For a small retail container use plastic bags, polymeric and glass bottles and banks, aerosol cans, tubas

Marking of disinfectantsMarking of disinfectants

name of manufacturer and its trademark; name of a product and its grade; number of party and tare place; production date; mass of gross and net; denotation of normative documentation.

Transportation of the disinsection means

Disinsection means transport alltypes of the closed transport according to

requirements of standard documentation of a concrete product

Disinsection means store in hermetically corked container in the place protected from light,

in the isolated rooms and in the distance from rooms of storage of any kinds of production.

Bags, drums, boxes with disinsection means stack

on a wooden flooring in a stack no more than 3,5 m high.

Storage of disinsection means

CosmeticsCosmetics

Facilities that are used for the care of skin,

it is executed hair, nails, oral cavity

hygienical, medical and preventive

and aesthetic functions.

(ДСТУ 2472 -94)

Classification of cosmetics

To destination and to structure

the hygienic

On consistences

liquid (lotions, emulsions, shampoos, paints, solvents)

On sexual andto the age

to sign

pasty (creams, toothpastes, body scrubs)

for women

the treatment-and-prophylactic

the decorative

powdered (powder, dusting powders, tooth powders)

for men

for youth

for children

solid (compact powder, lipsticks, deodorants)

protective( hand cream, antisun etc.)

medical (applied by the medical personnel)

theatrical(make-up)

General requirements to cosmetics

Constancy of quality inflow of warranty term

Safety of allthe ingredients entering

in structure of the cosmetic means

High degree efficiency of action

cosmetic

Stability to the action microorganisms

and to development oxidizing processes

Esthetic appearance, the corresponding art

and advertizing registration of packing

Marking consumer packing of cosmetics

Product name

Production date (year, month)

Period of storageStandard designation

on a product

Number of tone or color (for the products which are issued

on tones);

Name and address enterprises of the manufacturer,

its trademark

Packing of cosmetic productsPacking of cosmetic products

Name of Name of containercontainer

Material CosmeticsCosmetics CorkingCorking

JarsJars glass, polymeric, cryolite, glass, polymeric, cryolite, metal, combinedmetal, combined

creams fatty, hair creams fatty, hair preparations, fat blush, preparations, fat blush, vaselinevaseline

Polymeric or metal Polymeric or metal coverscovers

Tubas polymeric, aluminum, polymeric, aluminum, laminatnylaminatny

creams, toothpastes, creams, toothpastes, vaseline, etc.vaseline, etc.

Polymeric dispersersPolymeric dispersers

Cases metal, plastic, combinedmetal, plastic, combined lipstick, pencils for lipstick, pencils for eyebrows and eyelids, eyebrows and eyelids, paint for eyebrowspaint for eyebrows

Dispersers from the Dispersers from the same materialssame materials

Boxes cardboard, plastic, metal, cardboard, plastic, metal, combinedcombined

dental and soapy dental and soapy powders, powdery powders, powdery shampoos, powdershampoos, powder

The top of box is glued The top of box is glued up by a paper or delays up by a paper or delays a cellophanea cellophane

Bottles glass, porcelain, polymericglass, porcelain, polymeric liquid creams, lotions, liquid creams, lotions, dental elixirs, liquid dental elixirs, liquid facilities on the care of facilities on the care of skin and hair, nail polish skin and hair, nail polish and otherand other

Ground-in glass corks, Ground-in glass corks, screw-on lids, screw-on lids, dispersers with a dispersers with a locking conelocking cone

Cosmetic products store in pure, well ventilated warehouse with relative humidity no more than 70% and at a temperature from 50 with to 250 C, direct sunshine protected from action.

To the location and piling of commodity at storage next requirements are produced:

-commodities must take place so that round them there was circulation of air and overhead commodities did not cause spoilage of wares being below;

-- the labels of all commodities must be extrorse;-- all commodities in jars or small bottles must take place corking up;-- products have to be stored far from heating devices.-Warranty period of storage of the majority of cosmetic products at which it

shouldn't be observed noticeable change of quality – 12 months from the moment of release; powdery and compact products of decorative cosmetics, and also decorative cosmetics on a fatty basis – 18 months, liquid and biological creams – 6 months.

Storage of cosmetic productsStorage of cosmetic products

Leeches ((HirudineaHirudinea)) – – class of invertebrates of animals of type of annlidess,

that is divided by 2 subclasses - old leeches and real. The body of leech is extended

(to 150 mm), dense, flat or

cylindrical, greenish, brown or black color.

2 forms are known:

Leeches medical

pharmaceutical the medical

They differ in colouringand by the form of different lines on a body

Leeches medical, used in medical aims,

Ukraine Leech medical

Европа Bloodsucker dappled

Japan Bloodsucker Japanese

Storage of bloodsuckers

Leeches medical keep in a clean, light apartment, avoiding direct sunbeams at an optimal temperature

18-200 С. Indoors any smells aren't allowed. The container has to be pure, convenient for the washing, harmless.

It is better to use 3-5 one-liter glass jars with a wide throat or open cylindrical vessels.

For storage of bloodsuckers use pure, defended (two days) tap water,

which change daily.In a 3-one-liter jar place from 50 to 100 individuals.

At the disease of leeches(languor) and in hot weather water change twice in a day.

Expiration date of bloodsuckers: before preservation of biological full value.