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Nate johnson. Biology Honors 10 April 29, 2014 Mrs. Pedzisa. Rheumatoid Arthritis. Rheumatoid arthritis. - PowerPoint PPT Presentation

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Biology Honors 10April 29, 2014Mrs. Pedzisa Nate johnsonRheumatoid Arthritis

Rheumatoid arthritisRheumatoid arthritis (RA) is an autoimmune disease that results in a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks flexible (synovial) joints. It can be a disabling and painful condition, which can lead to substantial loss of functioning and mobility if not adequately treated.

The process involves an inflammatory response of the capsule around the joints (synovium) secondary to swelling (turgescence) of synovial cells, excess synovial fluid, and the development of fibrous tissue (pannus) in the synovium. The pathology of the disease process often leads to the destruction of articular cartilage and ankylosis (fusion) of the joints. RA can also produce diffuse inflammation in the lungs, the membrane around the heart (pericardium), the membranes of the lung (pleura), and white of the eye (sclera), and also nodular lesions, most common in subcutaneous tissue.3CAUSE of raThe causes of Arthritis is unknown unfortunately. Even though infectious agents such as viruses, bacteria, and fungi have long been suspected, none has been proven as the cause. The cause of rheumatoid arthritis is a very active area of worldwide research. It is believed that the tendency to develop rheumatoid arthritis may be genetically inherited (hereditary). It is also suspected that certain infections or factors in the environment might trigger the activation of the immune system in susceptible individuals. This misdirected immune system then attacks the body's own tissues. This leads to inflammation in the joints and sometimes in various organs of the body, such as the lungs or eyes.Effects of raEffect #1

Rheumatoid arthritis often starts in the small joints of the hands and feet but can progress to other parts of the body. Pain is often worse in the morning and is sometimes symmetrical.EFFECT #2

People with RA have twice the risk of having a heart problem as those without it. The condition creates a chronic, low-grade inflammation that damages blood vessels and increases the risk of heart attack, stroke, heart disease, and heart failure.Effect #3

Up to 10% of RA patients develop serious lung problems. The most common conditions are inflammation in the lungs' lining (pleurisy), which causes pain when breathing; scarring of the tissue in the lungs (pulmonary fibrosis); and an increased chance of emphysema, even in nonsmokers8conclusionRA is an autoimmune disease that results in a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks flexible (synovial) joints. The cause of RA is unknwn unfortunately. However, it can affect your heart, joints, and lungs

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