Nanotechnology: The ability to observe, measure, study and create at the molecular

and atomic level.

Atomic (electronic) structure

Molecular structure

Physical characteristics Electrical characteristics Biological characteristics

Why is understanding the molecular or atomic level structure

of a material important?

Biological Systems

Nano materials

Tools of Nanoscience

System and interactionunderstanding

Bio mimicryDiagnosisTreatment

Using the Tools

To Understand, Measure and Study

Understanding and Imitating Nature

Nanoscale Concepts Directly Tie to Biology

Surface area to volume ratio

No giant cells!!!!

Nanoscale Concepts Directly Tie to Biology

Properties Dependent on Size

Nanoscale Concepts Directly Tie to Biology

Priorities of Forces and Interactions

Deposition of Unlabeled ProteinsN-Goat IgGN-Mouse IgGN- Rabbit IgG

Incubate with:Donkey anti-goat

488Chicken anti-mouse

547Chicken anti-Rabbit

657

Evolution of DNA Sequencing

What’s next?– Pacific

Biosciences—Web site touts the $100 genome, long reads

•http://www.pacificbiosciences.com/assets/files/pacbio_technology_backgrounder.pdf•http://www.pacificbiosciences.com/assets/files/pacbio_technology_backgrounder.pdf