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WORLD OF NANOCONSTRUCTS

Nanoconstructs involves the

manipulation and application ofengineered particles or systems that haveat least one dimension less than 100nanometers (nm) in length.

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TREE OF NANOCONSTRUCTS

Nanoemulsions

Nanoplexes

Liposomes

Nanovesicles

Nanotubes

Nanocomposites

SLN/NLC

Nanosomes

Nanoviscers

DendrimersNanoparticles

Nanoparticles

Nanoparticles

Nanoparticles

Nanoparticles

NanoparticlesNanoparticle

s

Nanoparticles

Nanoparticles

Nanoparticles

Nanoparticles

Nanoparticle

s

Nanoparticles

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WHAT DO YOU WISH FOR

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WHERE HAVE WE REACHED TODAY.

NANOROBOTICS

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OPPORTUNITIES:

Nanomaterials in used in consumer products Numerous applications are being reported in the biomedical

field, especially as drug-delivery agents, biosensors orimaging contrast agents .

The applications pertaining to drug delivery involve

deliberate direct ingestion or injection of nanoparticles intothe body. Nanomaterials for imaging and drug delivery are often

intentionally coated with biomolecules such as DNA,proteins, and monoclonal antibodies to target specific cells

Materials in this size range may approach the length scale atwhich some specific physical or chemical interactions withtheir environment can occur.

Apart from this, due to their extremely small size,nanomaterials possess extremely high surface area tovolume ratio which renders them highly reactive.

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THREATS:

High reactivity potentially could lead to

toxicity due to harmful interactions of

nanomaterials with biological systems and

the environment

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NANOTOXICOLOGY:

Nanotoxicology wasproposed as a new branchof toxicology to addressthe gaps in knowledge andto specifically address the

adverse health effectslikely to be caused bynanoconstructs.

Study of Nanotoxicologyrelates to

the development of asustainable and safe nano-constructs

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ISSUES OF TOXICITY OF NANOCONSTRUCTS

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NANOTOXICOLOGY INCLUDES:

Nanotoxicology encompasses the physicochemical determinants, routes of exposure, biodistribution, molecular determinants, genotoxicity, regulatory aspects.

In addition, nanotoxicology is involved inproposing reliable, robust, and data-assuredtest protocols for nanomaterials in human andenvironmental risk assessment

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PATHOLOGICAL EFFECTS OF NANOPARTICLES

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TOXICOLOGY TESTS:

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GAPS TO BE FILLED:

Nanotechnology is growing at anexponential rate and will undoubtedly haveboth beneficial and toxicological impact and

consequences on health and theenvironment.

The importance of nanotechnologies to ourwell being is beyond debate, but its potential

adverse impacts need to be studied all themore.

Nanotoxicology as a new discipline shouldmake an important contribution to the

development of a sustainable and safe

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THANK YOU