nadh:fmn- oxidoreductase
DESCRIPTION
NADH:FMN- oxidoreductase. from Vibrio Fischeri Выполнила Кириллова Мария ФБ0801с. http://www.rcsb.org/pdb/explore/explore.do?structureId=1VFR. Aliivibrio fischeri. Bacteria; Proteobacteria ; Gammaproteobacteria ; Vibrionales ; Vibrionaceae ; Aliivibrio . - PowerPoint PPT PresentationTRANSCRIPT
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NADH:FMN-oxidoreductase
from Vibrio Fischeri
Выполнила Кириллова МарияФБ0801с
1http://www.rcsb.org/pdb/explore/explore.do?structureId=1VFR
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Aliivibrio fischeriBacteria;Proteobacteria; Gammaproteobacteria; Vibrionales;Vibrionaceae;Aliivibrio.
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NADH:FMN-оксидоредуктаза катализирует реакцию:
NADH + FMN → NAD+ FMNH2
Является гомодимером, и каждый мономер связывается с FMN как с кофактором
EC 1.6.8.1
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FMNNADPH
FMNH2NADP+
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http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?Dopt=s&uid=96435
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NAD(P)H\:FMN OXIDOREDUCTASE
flavin mononucleotide
http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?Dopt=s&uid=96436
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217 аминокислотных остатков:48% спирали (14 спиралей; 106 остатков)16% β-листов(8 нитей; 35 остатков)
7http://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=1VFR¶ms.annotationsStr=DSSP%2CSCOP¶ms.showJmol=false
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FMN
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=444243http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=444243 8
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FMNComputed Properties:
• Molecular Formula C17H21N4O9P+
• Molecular Weight 457.351741 [g/mol]
• H-Bond Donor 7• H-Bond Acceptor 10• Heavy Atom Count 31• Formal Charge 1• Covalently-Bonded Unit Count 1
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10http://www.rcsb.org/pdb/explore/explore.do?structureId=1VFR
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NADPH
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5886
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http://www.brenda-enzymes.org/Mol/Mol.php4?n=14331
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NADPH• Computed Properties:
• Molecular Weight 744.412943 [g/mol]• Molecular Formula C21H29N7O17P3+
H-Bond Donor 9• H-Bond Acceptor 17• Heavy Atom Count 48• Formal Charge 1 • Covalently-Bonded Unit Count 1•
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Где изучают ЯпонияСШАРоссияКитайВеликобритан
ияФинляндия
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• Houston • Tokyo • Yokohama• Kyoto • Shizuoka, Japan • Krasnoyarsk • Moscow, Russia • Zhongxing • Athens, USA • London • Turku • College Station
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14http://gopubmed.org/web/gopubmed/1?WEB01418s2w7gmm65IiIxI0
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Кто изучает Zenno S Saigo K Tu S Tanokura M Inouye S Lei B Jeffers C Koike H Sasaki H Koike H Hirayama S Karatani H Izuta T Maruhashi K Ishii Y Konishi J Suzuki M Van Hoek A Vetrova E Kudryasheva N Visser A
Wang H Yu Y Tang C Nichols J Danilov V Mazhul' M Zavil'gel'skiĭ G Zarubina A Iudina Nohmi T Watanabe M Nishino T Takio K Sofuni T Kobori T Murphy M Adman E Weng S Lin J Chao Y Lee J
Petushkov V Li W Parry R Nakamura H Kanoh H Rabin B Harbron S Eggelte H Benson S Ståhlberg T Lavi J Raunio R Baldwin T Daubner S Astorga A Leisman G Hjertén S Brolin S DeLuca M Jablonski E
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Где об этом пишут Biochemistry-us J Bacteriol Photoch Photobio Sci Arch Biochem Biophys Biochem Bioph Res Co J Biolumin Chemilumin J Biosci Bioeng Luminescence Mikrobiologiia J Biol Chem J Mol Biol Eur J Biochem J Biochem J Struct Biol Febs Lett P Natl Acad Sci Usa Mol Cell Biochem
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Используемые базы данных
http://www.rcsb.org/pdbhttp://www.ncbi.nlm.nih.gov/pubmed http://www.gopubmed.org
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