mother and child health: research methods
DESCRIPTION
Mother and Child Health: Research Methods. G.J.Ebrahim Editor Journal of Tropical Pediatrics, Oxford University Press. Programmes Menu of Epi-Info. The Normal Distribution. A histogram provides a view of how the values of a variable are distributed. Number of values and the Gausian shape. - PowerPoint PPT PresentationTRANSCRIPT
Mother and Child Health: Research Methods
G.J.Ebrahim
Editor
Journal of Tropical Pediatrics, Oxford University Press.
Programmes Menu of Epi-Info
The Normal Distribution
• A histogram provides a view of how the values of a variable are distributed.
Number of values and the Gausian shape
• All these histograms illustrate a Normal distribution. As the number increases the Gausian shape becomes more obvious
Scatterplot to show relationship between two numeric variables
• A scatterplot of dose of anaesthetic and time to recover from anaesthesia, with a regression line and 95% confidence intervals as well as outliers.
Outliers
• An outlier is an unusually high value of Y for a given value of X. Outliers exert an influence on the regression line.
Rates, Proportions and Ratios
Is numerator included in the denominator?
Yes No
Is time included in denominator?
Yes No
MEASURE: Rate Proportion Ratio
EXAMPLE: Incidence Prevalence Maternal Mortality
Rate Rate ratio
Absolute risk, Probability of survival and Odds ratio
Absolute Risk Survival Probability
Odds
0.90 1−0.90 = 0.10 0.90÷(1−0.9) =9.0
0.75 1−0.75 = 0.25 0.75÷(1−0.75) = 3.0
0.50 1−0.50=0.50 0.50÷(1−0.50)=1.0
0.25 1−0.25=0.75 0.25÷(1−0.25)=0.33
0.10 1−0.10=0.90 0.10÷(1−0.10)=0.11
0.01 1−0.01=0.99 0.01÷(1−0.01)=0.01
Calculating Numbers Needed to Treat (NNT)
• Calculate the proportion of people who have the outcome in the intervention group. (Exp.Grp.Evnt Rate; EGER )
• Calculate the proportion of people who have the outcome in the control (placebo) group. (Cntrl. Grp.Event Rate; CGER)
• Calculate the difference between EGER and CGER to obtain Absolute Risk Reduction (ARR)
• Then NNT = 1÷ARR