monthly prostaglandin bibliography prepared by the university of sheffield biomedical information...

TWICE MONTHLY BIBLIOGRAPHY ON PROSTAGLANDINS BIOLOGY-EARLY DECEMBER PREPARED BY SHEFFIELD UNIYERSITY BIOMEDICAL INFORMATION SERVICE

SHEFFIELD SlO 2TN

2. GENERAL Wilson T. Gandendren Iv/ Univ Dundee, Ninewells Hcsp & Med Sch, Dept Obstet & Gvnaecol. Dundee DD19SY. Scotland PR%X&ANDINS 1992,44 (4) 373 Serum concentrations of secretory IgA in pregnancies delivering at term or preterm.

PRECURSORS 4. Arachidonic Acid Zlli D, Voelkeljohnson C, Skinner T, Laster SM// N Carolina State Univ, Dept Microbial, Raleigh, NC 27695, USA BIOCHEM BIOPHYS RES COMMUN 1992,188 (1) 177 The adenovirus E3 region 14.7 kDa protein, heat and sodium arsenite inhibit the TNF-induced release of arachidonic acid.

Schiess K, Kaszkin M, Jordan P, Seidler L, Kinzel V*// *German Cant Res Ctr, Dept Pa- thochem, Im Neuenheimer Feld 280, W-6900 Heidelberg, FRG BIOCHIM BIOPHYS ACTA 1992,1137 (1) . 82 Mobilization of diacylglycerol in intact HeLa cells by exogenous phospholipase C from Cl perfringens is accompanied by release of fatty acids including arachidonic acid.

McIearie J, Sinclair RS, Chacon JN, Smith FJ*// l Univ Paisley. Dept Chem & Chem Et& Paisley PAi2BE; Renfrew, Scotland CHEM PHYS LIPIDS 1992.62 (2) 165 Synthesis and characterisation of the photosensitized oxidation reaction products of phenyl esters of linolenic and arachidonic acids.

Arai H, Nagano Y, Narumiya S, Kita T// Kyoto Univ, Dept Geriatr Med 8 Pharma- col, 54 Kawahara Cho, Sakyo ku, Kyoto 606, Japan J BIOCHEM TOKYO 1992,l12 (4) 482 Decreased arachidonate metabolism in mouse peritoneal macrophages after foam cell transformation with oxidized low-density lipoproteins.

Addy ME, Schwartzman MU/ Univ Ghana, Dept B&hem, Legon, Ghana PHYTOTHER RES 1992,6 (5) 245 An extract of Desmodium adscendens inhibits NADPHdependent oxygenation of arachidonic acid by kidney cortical microsomes.

5. PROSTAGLANDINS E AND F Gobbetti A, Zerani M, Cardellini LB// Univ Camerino, Dept Molec Cellular gL Anim Biol, Via F Camerini 2, I-62032 Camerino, Italy PROSTAGLANDINS 1992,44 (4) 277 A possible role of prostaglandin E2 in repro- duction of the male water frog, Rana esculen- ta - in vivo and in vitro studies.

Mizugaki M, Nishikawa M, Hishinuma T, Ohvama Y. Ishibashi M// Tohoku Univ, De& Pharmceut Sci, l-l Seiryo Machi, Aoba ku, Sendai, Miyagi 980, Japan PROSTAGIANDINS 1992,44 (4) 317 Analysis of the eicosapentaenoic acid (EPA) metabolite dell7-6-keto-PGFlalpha in human plasma by GUSIM using [18O]del17-6- keto-PGFlalpha.

Hishinuma T, Shimomum K, Nishikawa M, Ohvama Y. Ishibashi M. Mizunaki M*// *To- hoku Univ; Dept Pharmceut S& l-l Seiryo Machi, Aoba ku, Sendai, Migi 988, Japan PROSTAGLANDINS 1992,44 (4) 329 Sepamtion and concentration of dell7-6-keto- PGFlalpha using monoclonal antibody to omega3-olefin structure of trienoic pmsta- noids.

Weems CW, Vincent DL, Weems YS// Univ Hawaii, Dept Anim Sci, Honolulu, Hi 96822, USA REPROD FERT DEVELOP 1992,4 (3) 289 Roles of prostaglandins (PG) FLalpha, El, E2, oestradiol-17beta, histone-H2A and progesterone of conceptus, uterine or ovarian origin during early and mid pregnancy in the ewe.

Silvia WJ// Univ Kentucky, Dept Anim Sci, Lexington, KY 48546, USA REPROD FERT DEVELOP 1992,4 (3) 307 Uterine secretion of prostaglandin F2alpha in the ewe - regulation at the cellular level by ovarian hormones and the conceptus.

Jenkin G// Monash Univ, Dept Phyaiol, Clay- ton, Vie 3168, Australia REPROD FERT DEVELOP 1992,4 (3) 321 Interaction between oxytocin and pmstaglandin F2alpha during luteal regression and early pregnancy in sheep.

Mazurov VI, Lila AM, Pmkopyev AA, Blokhin MP// SM Kimv Mil Med Acad, Chair Hematol & Clin Immunol, St Peters- burg, Russia TERAPEVT ARKH 1992,&l (5) 20 Alteration of monokines and prostaglandin- E2 production by peripheral blood monocytes in patients with different clinico-immu- nologic varieties of rheumatoid arthritis (Rus- sian)

Kawase T, Orikasa M, Suzuki Al/ Niigata Univ, Sch Dent, Dept Pharmacol, Gakkccho Dori, Niigata 951, Japan CELL SIGNAL 1992,4 (5) 479 Phorbol ester-like action of staumsporine on the CAMP response to prostaglandin E2 in 2 macrophage-like cell lines at distinct differentiation states.

Ballou LR, Chao CP, Holness MA, Barker SC. Raghow R// Univ Tennessee Ctr Hlth Sci; Deit Med, Div Connect Tissue Dis, 956 Court Ave, Rm G326, Memphis, Tn 38163, USA J BIOL CHEM 1992,267 (28) 20004 Interleukin-l-mediated PGE2 orcduction and sphingomyelin metabolism - evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide.

Goddard DH, Grossman SL, Newton R, Clark MA, Bomalaski JS// Winthrop Univ Hosp, Dept Med, Div Rheumatol Immunol Allergy, 222 Stn Plaza N, Suite 430, Mineola, NY 11501, USA CYTOKINE 1992,4 (5) 377 Regulation of synovial cell growth - basic fi- broblast growth factor synergizes with interleukin 1 beta stimulating phospholipase A2 enzyme activity, phospholipase A2 activating protein production and release of prostaglandin E2 by rheumatoid arthritis synovial cells

in culture.

Kristula M, Bartholomew R, Galligan D, Uhlinger CJ/ Univ Penn, Sch Vet Med, Dept Clin Studies, Kennett Sq, Pa 19348, USA J DAIRY SCI 1992,75 (10) 2713 Effects of a prostagfandin F-2-alpha syn- chronization program in lactating dairy cattle.

Claus R, Dimmick MA, Gimenez T, Hudson LW// Univ Hohenheim, Inst Anim Husb, W- 7000 Stuttgart 70, FRG THERIOGENOLOGY 1992,38 (4) 687 Estrogens and prostaglandin F2alpha in the semen and blood pIasma of stallions.

Hayashi T, Mori I, Yamamoto H// Yamagu- chi Univ, Fat Agr, Vet Path01 Lab, 1-1677 Yoshida, Yamaguchi 753, Japan INT J EXP PATHOL 1992,73 (5) 593 Lactic dehydmgenase virus infection prevents development of anti-nuclear antibody in (NZB x NZW)Fl mice - role of prostaglandin-E2 and macmphage-Ia antigen expression.

6. PROSTACYCLIN Nadasy GL, Szekacs B, Juhasz I, Monos E // Semmelweis Univ Med, Exptl Res Inst, Ulloi 78-A, H-1882 Budapest, Hungary PROSI’AGLANDINS 1992,44 (4) 339 Pharmacological modulation of pmstacyclin and thmmboxane production of rat and cat venous tissue slices.

Bull HA, Courtney PF, Rustin MHA, Dowd PM*// *Middlesex Hosp, Dept Dermatol, Mot-timer St, London WlN 8AA, England BRIT J PHARMACOL 1992,107 (2) 276 Characterization of histamine receptor sub-

~m;ee~~;~;~l;ose;~lin release from

Ito S, Hashimoto H, Negishi M, Suzuki M, Koyano H, Ncyori R, Ichikawa A// Osaka Biosci Inst, Dept Cell Biol, 6-24 Furuedai, Suita 565, Japan J BIOL CHEM 1992,267 (28) 20326 Identification of the prostacyclin receptor by use of [15-3H1]19-(3-azidophenyl)-20-noriso- car bacyclin, an irreversible specific photoaf- finity probe.

7. THROMBOXANES Shin Y, Romstedt KJ, Markovich KM, Miller DD, Feller DR*// *Div Pharmacol, Ohio State Univ, 500 West 12th Ave, Columbus, Oh 43210-1291, USA PHARMACOL COMMUN 1992,1’(4) 303 Stereospeciflc interactions of nonpmstanoid trimetoquinof analogs with thmmboxane AUprostaglandin H2 receptor sites in human and rat platelets, and rat vascular endothelial and smooth muscle cells.

MacLennan SJ, Martin GR// Wellcome Res Labs, Biochem Sci, Analyt Pharmacol Grp, Beckenham BR3 3BS, Kent, England BRJT J PHARMACOL 1992.107 (2) 418 Effect of the thmmboxane AZ&mimetic U46619 on 5-HTl-like and 5HI%eceotor- mediated contraction of the rabbit i&ted femoral artery.

Takiguchi Y, Wada K, Nakashima M/l Hama- matsu Univ, Sch Med, Dept Pharmacol, Ha-

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mamatsu, Shizuoka 43131, Japan THROMB HAEMOST 1992,68 (4) 460 Comparison of the inhibitory effects of the TXA(2) receptor antagonist, vapiprost, and other antiplatelet drugs on arterial thrombosis in rats - Possible role of TXA(2)

Landolfi R, Ciabattoni Cl, Patrignani P, Cas- tellana MAL, Pogliani E, Bii B, Patron0 C*// l Univ G Dannunzio, Dept Pharmacol, Via Vestini 31, I-66013 Chieti, Italy BLOOD 1992,80 (8) 1965 Increased thrombozane biosynthesis in pa tients with polycythemia vera - Evidence for aspirin-suppressible platelet activation in vivo.

8. LEUKOTRIENES Iacoviello L, Amore C, Decurtis A, Tacconi MT, Degaetano G, Cerletti C, Donati MB// Consorzio Mario Negri Sud, Ist Ric Farma- col Mario negri, Thrombosis Pharmacol Lab, Via Nazi, 1-66030 Santa Maria Imbar, Italy ARTERIOSCLER THROMB 1992,12 (10) 1191 Modulation of fibrinolytic response to venous occlusion in humans by a combination of low-dose aspirin and n-3 polyunsaturated fatty acids.

Kishikawa K, Tateishi N, Maruyama T, Seo R, Toda M, Miyamoto TN Ono Pharmaceut Co Ltd, Minase Res Inst, Mishima, Osaka 618, Japan PROSTAGLANDINS 1992,44 (4) 261 Ono4057, a novel, orally active leukotriene B4 antagonist - effects on LTB4-induced neutrophil functions.

Moller JM, Svaneborg N, Lelvang HH, Varming K, Madsen P, Dyerberg J, Schmidt EB// Aalborg Hosp, Dept Endocrinol, DK- 9OOCl Aalborg, Denmark THROMB RES 1992,67 (5) 569 The acute effect of a single very high dose of n-3 fatty acids on coagulation and fibrinolysis.

Shirasaki H et al RHINOLOGY 1992,30 (1) 41-8 The roles of histamine, leukotriene C4 and bradykinin on nasal vascular permeability in experimental nasal allergy of guinea pigs.

Obata T, Kobayashi T, Okada Y, Nakagawa N. Terawaki T. Aishita H// Ono Pharmaceut Co Ltd, Minase Res Inst, Dept Preclin Res, 3- l-l Sakurai, Mishima, Osaka 618, Japan LIFE SC1 1992,51(20) 1577 Effect of a peptide leukotriene antagonist, ONO-1978 on antigen-induced airway micro- vascular leakage in actively sensitized guinea

pigs

Yoshimura Y, Nakamura Y, Ichikawa F, Oda T. Jinno M. Ando M. Kovama N. Shiokawa S /;Kyoiku &iv, Sch Med: Dept dbstet & Gynecol, 6-20-2 Shinkawa, Tokyo 160, Japan ACTA ENDOCRINOL 1992,127 (3) 246 Possible involvement of leukotrienes in human luteal function.

Malcolm KC, Fitzpatrick FA*// l Univ Colo- rado, Hlth Sci Ctr, Dept Pharmacol C 236, 4200 E 9th Ave, Denver, Co 88262, USA J BIOL CHEM 1992,267 (28) 19854 Epozyeicosatrienoic acids inhibit Ca2 + entry in platelets stimulated by thapsigargin and thrombin.

Chaney MO, Froelich LL, Gapinski DM, Mallett BE, Jackson WT’// *Eli Lilly % Co, Lilly Res Labs, Indianapolis, In 4628.5, USA

RECEPTOR 1992,2 (3) 169 Characterization of the spatial arrangement of the 2 acid-binding sites on the human neutrophil LTB(4) receptor.

Stratmann K, Boland W*, Muller DG// l Univ Karlsruhe, Inst Organ Chem, Richard Willstatter Allee 2, W-7500 Karlsruhe, FRG ANGEW CHEM INT ED 1992,31(9) 1246 Pheromones of marine brown algae - a new branch of the eicosanoid metabolism.

Habib A, Maclouf J*// *Hop Lariboisiere, INSERM, U348,8 Rue Guy Patin, F-75475 Paris 10, France ARCH BIOCHEM BIOPHYS 1992,298 (2) 544 Comparison of leukotriene-A4-metabolism into leukotrieneC4 by human platelets and endothelial cells.

Chaukin RS, Davidson LD. Davidson W/ Tex& A&M Univ Syat, Dept Anim Sci, Molec & Cell Biol Gro. Coil Stn. TX 77843, . USA BIOCHEM J 1992,287 (OCI-) Pl, 237 Phospholipid molecular species composition of mouse liver nuclei - influence of dietary n- 3 fatty acid ethyl esters.

Leier I, Muller M, Jedlitschv G, Keppler D// Deutsch Krebsforschuneszentrum. Div Tumor Biochem, Neuenheiker Feld 280, W- 6900 Heidelberg, FRG EUR J BIOCHEM 1992,209 (1) 281 Leukotriene uptake by hepatocytes and hepa- toma cells.

Aukema HM, Yamaguchi T, Takahashi H, Philbrick DJ. Holub BJ*// l Univ Guelnh. Dept Nutr S& Guelph, Ontario, Canada’ NlG 2Wl NUTR RES 1992,12 (11) 1383 Effects of dietary fish oil on survival and renal fatty acid composition in murine poly- cystic kidney disease.

Gertner DJ, Rampton DS*, Denucci G, Cynk E, Lennardjones JE// *Royal London Hosp, Dept Gastroenterol, Whitechapel, London El lBB, England EUR J GASIROENTEROL HEPATOL 1992,4 (10) 837 Eicosanoid release by rectal mucosa in vitro in ulcerative colitis - effects of conventional and potential new therapies.

Lehmann B, Kampf A, Barth J// Carl Gustav Carus Med Acad, Dept Dermatol, Fet- scherstr 74, W-8019 Dresden, FRG PHOTODERMATOL PHOTOIMMUNOL PH1992,9(1)8 Transformation and degradation of leuko- trieneB4, 12-hydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid induced by ultraviolet radiation.

Yamaguchi T, Kohrogi H’, Honda I, Kawa- no 0, Sugimoto M, Araki S, Ando M// *Ku- mamoto Univ, Sch Med, Dept Internal Med 1, l-l-l Honjo, Kumamoto 860, Japan AMER REV RESP DIS 1992,146 (4) 923 A novel leukotriene antagonist, ONO-1078, inhibits and reverses human bronchial contraction induced by leukotrienes-C4 and leukotrienes-D4 and antigen in vitro.

Miller RF, Lefferts PL, Snapper JR*// *Van- derbilt Univ, Med Ctr, Sch Med, Dept Med, Ctr Lung Res, B-1398 Med Ctr N, Nashville, Tn 37232, USA AMER REV RESP DIS 1992,146 (4) 997

Effect of sulfidopeptide leukotriene receptor antagonists on endotozin-induced pulmonary dysfunction in awake sheep.

Goodnight SH, Cairns JA, Fisher M, Fitzger- ald GA// Univ Orenon. Hlth Sci Ctr. Euaene. Or97403,USA ”

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CHEST 1992,102 (4) Suppl, S374 Assessment of the therapeutic use of n-3 fatty acids in vascular disease and thrombosis.

Rabinovici R, Yue TL, Krausz MM, Sellers TS, Lynch KM, Feuemtein G// Thomas Jef- ferson Univ, Jefferson Med Coil, Dept Surg, 1025 Walnut St, Philadelphia, Pa 19107, USA SURG GYNECOL OBSIET 1992,175 (4) 341 Hemodynamic, hematologic and eicosanoid mediated mechanisms in 7%percent sodium chloride treatment of uncontrolled hemor- rhagic shock.

Pendino KJ, Chepenik KP, Schmidt RR*// Thomas Jefferson Univ, Jefferson Med Coil, Dept Anat, JAH Room 526,102O Locust St, Philadelphia, Pa 19187, USA IMMUNOL CELL BIOL 1992,70 (4) 237 Differential eicosanoid synthesis by murine fetal thymic non-lymphoid cells.

9. PLATELET-ACTIVATING FACTOR Damtew B, Spagnuolo PJ// Case Western Reserve Univ, Metrohlth Med Ctr, Dept Med, Cleveland, Oh 44109, USA INFLAMMATION 1992,16 (5) 425 Platelet activating factor amplifies human neutrophil adherence to bovine endothelial cells - evidence for a lipoxygenase dependent mechanism.

Oneill c// Univ Sydney, Royal N Shore Hosp, Dept Physiol, Human Reprod Unit, St Leonards, NSW 206.5, Australia REPROD FERT DEVELOP 1992,4 (3) 283 Embryo-derived platelet activating factor.

Yara A, Noguchi K, Nakasone J, Kinjo N, Hirayama c Sakanashi M// Univ Ryijkyus, Fat Med. Sch Med. Dent Pharmacol, 207 Ue- hara, Nishihara, Okinawa 90301, Japan TOXICON 1992,30 (10) 1281 Cardiovascular effects of Acanthaster planci venom in the rat - possible involvement of PAF in its hypotensive effect.

Bautista AP, Spitzer JJ//Dept Physiol, LSU- Med Ctr, 1901 Perdido Street, New Orleans, La 70112, USA FREE RADICAL RES COMMUN 1992.17 (3) 195 Platelet activating factor stimulates and primes the liver, Kupffer cells and neutro- phils to release superoxide anion.

Willette RN, Feuerstein GZ, E!aser KM, Bar- tus JO, Mitchell MP, Shiloh AO// Dept Phar- macol, UW2510,709 Swedeland Road, King of Prussia, Pa 19406, USA PHARMACOL COMMUN 1992,1(4) 329 SK&F EZOO2, a dual lipoxygenase/cyclooxygenase inhibitor, prevents changes in body weight and serum tumor necrosis factor elicited by lipopolysaccharide and platelet activating factor.

Shimizu T, Honda Z, Nakamura M, Bito H, Izumi T//Univ Tokyo, Fat Med, Dept Biochem, Hongo 7-3-1, Bunkyo ku, Tokyo 113, Japan BIOCHEM PHARMA COL 1992,44 (6) 1001

B26

Platelet-activating factor receptor and signal transduction.

Tsangaris GT, Demopoulos CA, Tsoukatos DC, Kapoulas VM//Univ Athens, Dept Chem, Panepistimioupolis, GR-15771 At- hens, Greece COMP BIOCHEM PHYSIOL PT C 1992, 102 (3) 495 Study of the glycogenolytic action of platelet activating factor in Tetrahymena pyriformis.

Ortiz JL, Cortijo J, Valles JM, Bou J, Morcil- lo El// Univ Valencia. Fat Med Odontol. Dept Farmacol, AV Blasco I Banez 15, E- 46010 Valencia, Spain FUNDAM CLIN PHARMA COL 1992,6 (6) 247 Rolipram inhibits PAP-induced airway micro- vascular leakage in guinea pig - A comparison with milrinone and theophylline.

Rolapleszczynski M, Stankova J// Univ Sher- brooke, Fat Med, Dept Pediat, Div Immu- nol, Sherbrooke, Quebec, Canada JlH 5N4 J LEUKOCYTE BIOL 1992,51(6) 609 Differentiation-dependent modulation of TNF production by PAF in human HL-60 myeloid leukemia cells.

Kroegel c/1 Univ Freiburg, Med Clin, Dept Pneumol. Huestetter Str 55, W-7800 Frei- burg, FRG ” EUR RESP J 1992,5 (8) 915 Does airway smooth muscle care about platelet-activating factor (Editorial)

Johnson PRA, Black JL, Armour CL// Univ Sydney, Dept Pharmacol, Sydney, NSW 2006, Australia EUR RESP J 1992,5 (8) 970 Platelet-activating factor-induced contraction of human isolated bronchus.

Lee TC, Uemura Y, Snyder F// Oak Ridge Associated Univ, Div Med Sci, Oak Ridge, Tn 37831. USA J BIOL THEM 1992,267 (28) 19992 A novel CoA-independent transacetylase pro- duces the ethanolamine plasmalogen and acyl analogs of platelet-activating factor (PAF) as the acetate donor in HL-60 cells.

Kitagawa S, Kubota Y, Yamaguchi T. Fuiimu- ra f Binnaka T, Tani K, Ogi& M, M&o T. Inoue K// Kansai Med Univ. Deut Inter- nal Med 3,1 Fumizono Cho, Mori&chi, Osaka 570, Japan J GASTROENIEROL HEPATOL 1992,7 (5) 481 Role of endogenous platelet-activating factor (PAF) in endotoxin-induced portal hyperten- sion in rats.

Kimoto M, Javom MA, Ekholm J, Siafakaka- nadai A. Hanahan DJ*// l Univ Texas. Hlth *Sci Ctr, Dept B&hem, .7703 Floyd Curl Dr, San Antonio, TX 78284, USA ARCH BIOCHEM BIOPHYS 1992,2% (2) 471 Dual effects of oleic acid on Ca2 + mobilization and protein phosphorylation in human platelets in presence or absence of platelet activating factor.

Chuvilin AN, Trusov VG, Serebrennikova GA// MV Lomonosov Fine Chem Technol Inst, Moscow, Russia BIOORG KHIM 1992,18 (6) 862 Synthesis of phosphono analogues of phos- pholipidic platelet activating factor (Russian)

Liu HL, Chao W, Olson MS*// l Univ Texas, Hlth Sci Ctr, Dept B&hem, 7703 Floyd Curl Dr. San Antonio, TX 78284, USA J BIOL CHEM i992,267 (29) 20811 Regulation of the surface expression of the platelet-activating factor receptor in IC-21 peritoneal macrophages - effects of lipopolysaccharide.

Stock AE, Hansel W// New York State Cdl Vet Med, Dept Physiol, Ithaca, NY 14853,

USA THERIOGENOLOGY 1992,38 (4) 757 Assay of embryo-derived platelet activating factor (EDPAF) by an equine platelet aggregation assay - preliminary data concerning its presence in bovine embryo culture media.

Wells XE, Oneill CO// l Univ Sydney, Royal N Shore Hosp, Dept Physiol, Human Reprod Unit, St Leonards, NSW 2065, Australia J REPROD FERTIL 1992, % (1) 61 Biosynthesis of platelet-activating factor by 2- cell mouse embtyos.

Bensard DD, Anderson BO, Banerjee A, Nelson DW. Potnzetti RS. Berens RL. Har- ken AH// Univ Glorado; Hlth Sci Ctr, Dept Surg, Denver, Co 80262, USA J SURG RES 1992,53 (4) 321 Platelet activating factor alters receptor- coupled function in the isolated perfused rat heart.

Tan WC, Bethel RA// Natl Univ Singapore Hosp, Dept Med, Singapore, Singap& AMER REV RESP DIS 1992.146 (4) 916 The effect of platelet activating factor antagonist on ozone-induced airway inflammation and bronchial hyperresponsiveness in guinea pigs.

Tam FWK Clague J, Dixon CMS, Stuttle AWJ, Henderson BL, Peters AM, Lavender JP. Ind PW*// ‘Hammersmith Hosn. Roval Postgrad Med Sch, Dept Med, Dep’t’Diag- nost Radio& Resp Unit, Ducane Rd, London W12 OHS, England AMER REV RESP DIS 1992,146 (4) 1003 Inhaled platelet-activating factor causes pulmonary neutrophil sequestration in normal humans.

Taniguchi H, Iwasaka T, Takayama Y, Su- giura T, Inada M// Kansai Med Univ, CCU, 1 Fumizono Cho, Moriguchi, Osaka 570, Japan CHESI 1992,102 (4) 1245 Role of platelet-activating factor in pulmonary edema after coronary ligation in dogs.

Atochina EN, Heimisch HH, Muzykantov VR, Danilov SM*// ‘Inst Exptl Cardiol, 3rd Cherepkovskaja St, 15A, Moscow 121552, Russia LUNG 1992,170 (6) 349 Systemic administration of platelet-activating factor in rat reduces specific pulmonary uptake of circulating monoclonal antibody to angiotensin-converting enzyme.

Nguer CM, Pellegrini 0, Galanaud P, Ben- veniste J. Thomas Y. Richard Y*// *IN- SERM, U131,32 Rue Camets, FL92140 Cla- mart, France J IMMUNOL 1992, 149 (8) 2742 Regulation of PAF-acether receptor expression in human B-cells.

Hiraide A, Evans RD, Williamson DH*// *Radcliffe Infirm, Nuflield Dept Anesthesia, Metabol Res Lab, Woodstock Rd, Oxford OX2 6HE, England

CLIN SCI 1992,83 (4) 495 Platelet-activating factor causes hypoketo- naemia in starved rats.

10. METABOLITES Delvecchio RP, Matsas DJ. Inzana TJ, Sponenberg DP, Lewis GS// Louisiana State Univ, Dept Vet Sci, Baton Rouge, La 70803, USA J ANIM SCI 1992,70 (10) 3158 Effect of intrauterine bacterial infusions and subsequent endometritis on prostaglandin F2alpha metabolite concentrations in postpar- tum beef cows.

Wagner 8, Eichler HG, Schneider B, Bloehl- daum B, Brenner B, Gasic S, Lechner K, Kyrle PA*// l Univ Vienna, Dept Med 1, Div Hematol & Hemostaseol. Wahringergurtel 18-20, A-1000 Vienna, Austria NAUNYNSCHMIED ARCH PHARMA- COL 1992,346 (4) 453 Studies on the effect of 2 angiotensin-converting enzyme inhibitors, captopril and cilaza- pril, on platelet and vascular prostaglandin metabolism in vivo.

Wennmalm A, Benthin G, Granstrom EF, Persson L, Winell S// Gothenburg Univ, Sahlgrens Hosp, Dept Clin Physiol, S-41345 Gothenburg, Sweden CLIN SC1 1992,83 (4) 461 2,3dinor metabolites of thromboxane A2 and prostacyclin in urine from healthy human subjects - diurnal variation and relation to 24h excretion.

11. RELATED ENZYMES Pruxanski W, Scott K, Smith G, Rajkovic I, Stefanski E, Vadas P// Univ Toronto, Inflam- mat Res Grp, Toronto, Ontario, Canada M5S 1Al INFLAMMATION 1992,16 (5) 451 Enxymatic activity and immunoreactivity of extracellular phospholipaseA2 in inflammatory synovial fluids.

Pruranski W. Wilmore DW, Suffredini A, Matrich GD; Hoffman AGD, Browning JL, Stefanski E. Stembv B. Vadas P// Univ To- ronto, Inflammat Res Grp, Toronto, Onta- rio, Canada M5S 1Al INFLAMMATION 1992,16 (5) 561 HyperphcspholipasemiaA2 in human volun- teers challenged with intravenous endotoxin.

Toh H, Yokoyama C, Tanabe T, Yoshimoto T, Yamamoto S// Protein Engn Res Inst, Suita, Osaka 565, Japan PROSTAGLANDINS 1992,44 (4) 291 Molecular evolution of cyclooxygenase and lipoxygenase.

Basavarajappa BS, Gowda TV*// l Univ My- sore, Dept Studies Biochem, Mysore 57tJOO6, Kamataka, India TOXICON 1992,30 (10) 1227 Comparative characterization of 2 toxic phos- pholipasesA2 from Indian cobra (Naja naja naja) venom.

Malmberg AB, Yaksh Tu/ Dept Anesthesiol 0818, Univ Calif San Diego, La Jolla, Ca 92093-0!318, USA SCIENCE 1992,257 (5074) 1276 Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.

Ghassemi A, Rosenberg P*// ‘Univ Connecti- cut, Sch Pharm, Pharmacol 8c Toxicol Sect,

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U-92, Storm, Ct 06269, USA BIOCHEM PHARMA COL 1992,44 (6) 1073 Effects of snake venom phospholipase A2 toxins (beta-bungatotoxin, notexin) and enzymes (Naja-naja-atra, Naja-nigricollis) on aminophospholipid asymmetty in rat cerebro- cortical synaptosomes.

Pruzanski W, Greenwald RA, Street IP, La- liberte P, Stefanski E, Vadas P// Univ Toron- to, Inflammat Res Grp, Toronto, Ontario, Canada M5S 1Al BIOCHEM PHARMA COL 1992,44 (6) 1165 Inhibition of enzymatic activity of phospholi- pases A2 by minocycline and doxycycline.

Grimes HD, Koetje DS, Franceschi VR// Washington State Univ, Dept Bot, Pullman, Wa 99164, USA PLANT PHYSIOL 1992, loo (1) 433 JSpxession, activity, and cellular accumula- tion of methyl jasmonate-responsive lipoxygenase in soybean seedling.

Spaargaren M, Wissink S, Defiie LHK, De- laat SW, Boonstra J// Univ Utrecht, Dept Molec Cell Biol, Padualaan 83384 CH Utrecht, Netherlands BIOCHEM J 1992,287 (OCI’) Pl, 37 Characterization and identification of an epidermal-growth-factor-activated phospholi- paseX!.

Konrad RJ, Jolly YC, Major C, Wolf BA*// *Univ Penn, Dept Pathol & Lab Med, Philad- elphia, Pa 19104, USA BIOCHEM J 1992,287 (OCT) Pl, 283 Carbachol stimulation of phospholipase-A2 and insulin secretion in pancreatic islets.

Wells 1, Mamett LI*// *Vanderbilt Univ, Med Ctr, Sch Med, Dept B&hem, Ctr Molec Toxicol, AB Hancock Jr Mem Lab Cant Res, Nashville, Tn 37232, USA BIOCHEMISI’RY-USA 1992.31(40) 9520 Acetylation of prostaglandin &do&&de synthase by N-acetylimidazole - comparison to acetylation by aspirin.

Krook M, Prozorovski V, Atrian S, Gonzalez- duatte R Jomvall H*// ‘Karolinska Inst. Dept Chem 1, S-10401 Stockholm 60, Sweden EUR J BIOCHEM 1992.209 (1) 233 Short-chain dehydrogensses - pi&teolysis and chemical modification of ptokaryotic 3alphan0beta-hydroxysteroid, insect alcohol and human 15hydroxyprostaglandin dehy- drogenases.

Sierrahonigmann MR, Murphy PA// Johns Hopkins Univ, Sch Med, Dept Pediat, Div In- fect Dis, Baltimore, Md 21205, USA PEPI’IDE RES 1992,s (5) 258 Suppression of interleukin-1 action by phospholipase-A2 inhibitors in helper-T lympho- cytes.

Butovich IA, Parshikova TV, Babenko VM, Livarchuk LV, Kharchenko OV, Kukhar VP// Chem Inst Toxicol, POB 12137, Res Triangle Pk, NC 27709, USA BIOL MEMBRANY 1992,9 (6) 611 Regulation of S-lipoaygenase activity in the reaction of linoleic acid oxidation by phos- pholipids (Russian)

Chemy W, Sikharulidze MG, Mirsky VM, Sokolov VS// AN Frumkin Electrochem Inst, Moscow, Russia BIOL MEMBRANY 1992,9 (7) 733 Potential distribution on the lipid bilayer membrane due to the phospholipaseA2 ac-

tivity (Russian)

Letko G, Siech M// Med Acad Maadebure Div Exptl Surg, Surg Clin, Leipzig& Str 4?, O-3090 Maedebure FRG DIGESI’IGN lm:51(4) 193 Effect of phospholipase-A2 and ethanol on the survival of acinar cells isolated from the rat pancreas.

Sanz LC, Petez AG, Rios JJ, Olias JM*// ‘CSIC, Inst Grass & Derivados, Avda Padre Garcia Tejero 4, E41012 Seville, Spain PHYTOCHEMISTRY 1992,31(10) 3381 Physicochemical properties of chickpea lipox- ygenases.

12. PRODUCTION AND RELEASE Cmtizo AM. Besterman JM. Leitner PP. Chandrabose KA// Glaxo Ini, Res Inst, S Moore Dr. Res Trianele Pk. NC 27709. USA PROSTAGLANDIN: 1992; 44 (4) 357 Stimulated release of arachidonate and prostaglandins is vectorial in MDCK epithelial cells.

Thatcher WW, Danetdesnoyers G, Wetzels C // Univ Florida, Dept Dairy Sci, Gainesville, Fl32611, USA REPROD FERT DEVELOP 1992,4 (3) 329 Regulation of bovine endometrial prostaglandin secretion and the role of bovine tropho- blast protein-l complex.

Gibb W, Randall GCB// Univ Ottawa, Otta- wa Gen Hasp, Dept Obstet & Gynecol, Div Perinatol, 501 Smyth Rd, Ottawa, Ontario, Canada KlH 8L6 CAN J PHYSIOL PHARMA COL 1992,70

(7)990 Prostaglandin production by porcine allanto- chorion invitro - Effect of cortisol infusion in- vivo.

13. EFFECTS Molderings Cl, Malinowska B, Schlicker E* /I l Univ Bonn, Inst Pharmacol & Toxicol, Reu- tetstr 2 B, W-5300 Bonn 1, FRG BRlT J PHARMACOL 1992,107 (2) 3.52 Inhibition of noradrenaline release in the rat vena cava via prostanoid receptors of the EP3-subtype.

Bergasa NV, Borque MJ, Wahl LM, Rabin L, Jones EA// NIDDKD, Digest Dis Branch, Liver Dis Sect, Bldg 10,4-D 52, Bethesda, Md 20892, USA LIVER 1992,12 (4) Pl, 168 Modulation of thioacetamide-induced hepato- cellular necrosis by pmstaglandins is associated with novel histologic changes.

Tokuka A, Tanaka A, Fujita T, Hayashi M, Kitai T, Yamaoka Y, Ozaws K, Ohnishi ST // Kvoto Univ. Fat Med. Dept Surg 2,54 Kawa- ra’ Cho, Sakyo ku, Kyoto 806, Japan TRANSPLANT INT 1992.5 (4) 193 Protective effect of a pro&g&din oligomer on liver mitochondria in situ - time-shared measurements of fluorescence and reflect- ance in the cold-preserved rat liver.

Reddy BB, Murthy ASN*, Rao AVN, Rao VSN N *Co11 Vet Sci, Tirupati, Andhra Pradesh, India - ANIM REPROD XI 1992,29 (l-2) 117 Role of seminal prostaglandins on fertility of Murrah buffalws.

Gray SJ, Giles H’, Posner J/l *Wellcome Res Labs, Dept Biochem !Sci, Beckenham

BR3 3BS, Kent, England BRIT J CLIN PHARMA COL 1992,34 (4) 344 The effect of a prostaglandin DP-receptor partial agonist (192C86) on platelet aggregation and the cardiovascular system in healthy volunteer.

14. PROSTAGLANDINS IN MEDICINE Salamalekis E, Loghis C, Kassanos D, Traka A, Zourlas PA// 2nd Deut Obstet & Gvne- I&, Univ Athens, AreteLon Hosp, 76 V&rilis- sis Sophias Ave, GR-115 28 Athens, Greece J OBSIET GYNECOL 1992,12 (2) 118-119 Comparison of extra-amniotic prostaglandin F2alpha and dinoprostone use for labour induction after second trimester intrauterine fetal death.

Bigrigg A, Chui D, Chissel S, Read M*// l Dept Obstet & Gynecol, Gloucestershire Royal Hosp, Great Western Rd, Gloucester GL13NN, England J OBSIEI’ GYNECOL 1992,12 (2) 125-129 Laparoscopic treatment of tubal pregnancies with 15methyl-prostaglandin F2alpha.

Toppozada M, El-Ghazzawi E, Meleis M, Abd-Rabbo S/i Dent Obstet & Gvnecol, Shatby Hasp, AIex&dria, Egypt . J OBSI-ET GYNECOL 1992.12 (4) 228231 Effect of 9deoxy-16,16dimethyl-d-r;lethylene- pros taglandin E2 vaginal gel on the tissues of the pregnant unripe cervix at term.

Sawada Y, Yotsuyanagi T, Hatayama I, Sone K/I Hirosaki Univ, Sch Med, Dept Plast & Reconstruct Surg, 53 Hon Cho, Hirosaki, Aomori 036, Japan BRIT J PLASI- SURG 1992,45 (6) 46.5 The relationship between prostaglandin-El applied area and flap survival rate.

Allen RP, Engel RM, Smolev JK, Brendler CB// Johns Hopkins Univ Hosp, Dept Ural, Baltimore, Md 21205, USA J UROL 1992,148 (4) 1181 Objective double-blind evaluation of erectile function with intracorporeal papaverine in combination with phentolamine and/or prostaglandin-El.

Schouman M, Lacroix P, Amer M// Ctr Ex- plorat & Traitements Androl, 24 Rue Pier- ret, F-92200 Neuilly, France J UROL 1992,148 (4) 1266 Suppression of prostaglandin El-induced pain by dilution of the drug with lidocaine be- fore intracavemous injection (Letter)

Papageorgiou I, Tsionou C*, Minaretzis D, Michalas S, Aravantinos D/1 l Univ Athens, Alexandra Matem Hosp, Dept Obstet & Gynecol 1,80 Vas Sophias Ave, GR-11528 Athens, Greece GYNECOL OBSIEI INVEST 1992,34 (2) 92 Labor characteristics of uncomplicated pro- longed pregnancies after induction with in- tracervical pmstaglandin E2 gel vemus intravenous oxytocin.

15. PROSTAGLANDINS AS DRUGS Handschuh H PERFUSION 1992,s (4) 124 Misoprostol protects high-risk patients against NSAI-induced gastropathies (Con- ference report)

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16. INHIBITORS OF SYNTHESIS Shiraishi M, Terao S// Takeda Chem Ind Ltd, Div Res & Dev, Chem Res Labs, 17-85 Jusohonmachi 2 Chome, Yodogawa ku, Osaka 532, Japan J SYN ORG CHEM JPN 1992,SO (9) 786 Synthesis and biological evaluation of newly designed quinone derivatives - 5-lipoxygenase inhibitors and thromboxaneA2 receptor antagonists (Japanese)

Unangst PC, Shrum GP, Connor DT, Dyer RD, Schrier DJ// Warner Lambert Parke Davis, Dept Chem, Parke Davis Pharmaceut Res Div, 2llOO Plymouth Rd, Ann Arbor, Mi 48105, USA J MED CHEM 1992,35 (20) 3691 Novel 1,2,4_oxadiaxoles and 1,2,4-thiadiaxoles

as dual S-lipoxygenase and cyclooxygenase inhibitors.

Neu IS, Mallinger J, Wildfeuer A, Mehlber U/ Stadt Krankenhaus Sindelf’ineen. Neural Abt, Postfach 445, W-7932 Sindeifingen, FRG J NEUROL 1992.239 (8) 470 Suppression of experimental autoimmune encephalomyelitis by a new specific leukotriene biosynthesis inhibitor (Letter)

17. Indomethacin Lundholm CE, Bartonek MN Fat Hlth Sci, Dept Pharmacol, S-58185 Linkoping, Sweden COMP BIOCHEM PHYSIOL PI C 1992, 102 (3) 379 Inhibition of eggshell formation in domestic fowl by indomethacin - Relation to calcium

and prostaglandin metabolism in the eggshell gland mucosa.

18. CHEMICAL SYNTHESIS Takahashi T, Shimayama T, Miyaxawa M, Na kaxmva M, Yamada H, Takatori K, Kajiwara M// Tokyo Inst Technol, Dept Chem Engn, Meguro ku, Tokyo 152, Japan TETRAHEDRON LEIT 1992,33 (40) 5973 New chiral synthetic intermediate for prostaglandins.

Kovacs I, Hercxegh P*, Batta G, Jeko J, Re- naud A, Sxtaricskai FJ// l I.aios Kossuth Univ, Hungarian Acad Sci, Antibiot Res Gro. POB 70. H-4010 Debrecen. Hunsarv J CARBOHYD CHEM 1992, li (7) G7’ Tartraldehydes. 5. Syntheses of chiral synthetic building blocks for some intermediates of the arachidonic acid cascade.

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TWICE MONTHLY BIBLIOGRAPHY ON PROSTAGLANDINS BIOLOGY- LATE DECEMBER PREPARED BY SHEFFIELD UNIVERSITY BIOMEDICAL INFORMATION SERVICE

SHEFFIELD SlO 2TN

1. BOORS, REVIEWS, SYMPOSIA Ristimaki A, Viinikka L*// l Univ Helsinki, Biochem Pharmacol, SF-00290 Helsinki 29, Finland PROSTAGLAND LEUK ESSENT FATTY 1992,47 ( 2) 93 Modulation of prostacyclin production by cytokines in vascular endothelial cells (Review)

Simopoulos AP (Ed) Karger (Base]), 1992,170 pp ISBN 3-805.5- 5594-6 $188.00 Hardbound SFR 23S.OO/DM 281.00 Nutrients in the Control of Metabolic Dis- eases. Includes chapter on Long-chain omega3 fatty acids are the most effective polyunsaturated fatty acids for dietary prevention and treatment of cardiovascular risk factors - conclu- sions from clinical studies

PRECURSORS 4. Arachidonic Acid Motta A, Franchi AM, Faletti A, Gimeno AL, Gimeno MAF’// l Consejo Nacl Invest Cient & Teen, Ctr Estudios Farmacol & Bat, Serrano 66.5, RA-1414 Buenos Aires, Argenti-

ZOSTAG- LEUK ESSENT FATTY 1992,47 ( 2) 139 On the role of in vivo injected progesterone and of the in vitro presence of oxytocin, modulating Ca2 + uptake by the rat uteri from spayed animals and as controllers of the production of arachidonic acid metabolism.

Omar HA, Figueroa R, Omar RA, Wolin MS’ // *New York Med Coil, Dept Physiol, Valhalla. NY 10595. USA AMER j OBSTET’GYNECOL 1992,167 (4) 1064 Properties of an endogenous arachidonic acid elicited relaxing mechanism in human placental vessels.

Dray F, Vulliezlenormand B, Deroussent A, Briquet I, Gabellec MM, Nakamura S, Wahl LM. Gouvette A, Salahuddin ZS// CHU Co- chin Portkoyal, Dept Biophys, 24 rue Faub- oure St Jacaues, F-75014 Paris, France BIGCHIM BIOPHYS ACI-A 1992,1X30 (1) 83 Active metabolism of arachidonic acid by Ka- posi sarcoma cells cultured from lung bib- psies (KS-3) - identification by HPLC and MS/MS of the predominant metabolite se- creted as the 11,12-epoxy-eicosatrienoic acid.

Gong MC, Fuglsang A, Alessi D, Kobayashi S. Cohen P. Somlvo AV. Somlvo AP’II ‘Univ Virginia, &h Med, Dep’t Physiol, Box 449, Jordan Hall, Charlottesville, Va 22908, USA J BIOL CHEM 1992,267 (30) 21492 Arachidonic acid inhibits myosin light chain phosphatase and sensitizes smooth muscle to calcium.

Juergens UR, Christiansen SC, Stevenson DD, Zuraw BL’// ‘Scripps Clin & Res lnst, 10666 N Torrey Pines Rd, La Jolla, Ca 02037, USA J ALLERG CLIN IMMUNOL 1992,90 (4) 636 Arachidonic acid metabolism in monocytes

of aspirin-sensitive aasthmatic patients be- fore and after oral aspirin challenge.

Orourke AM, Mescher MF, Apgar JR*// *Med Biol Inst. Div Membrane Biol, 11077 N Torrey Pines Rd, La Jolla, Ca 92037, USA MOL IMMUNOL 1992,29 (11) 1299 IgE receptor-mediated arachidonic acid release by rat basophilic leukemia (RBL2H3) cells - possible role in activating degranula- tion.

Liu P, Kawada N, Mizoguchi Y*, Morisawa S// *Osaka City Univ, Sch Med, Dept Inter- nal Med 3, l-S-7 Asahi Machi, Abeno ku, Osaka 545, Japan GASTROENTEROL JPN 1992,27 (5) 624 Arachidonate metabolism in D-galacto- samine or carbon tetrachloride-induced acute and chronic liver injuries in rata.

Capdevila JH, Wei S, Yan J, Karara A, Jacobson HR Falck JR Gueneerich FP, Du- bois RN// Vanderbilt Univ, Mgd Ctr, North S-223, Nashville, Tn 37232, USA J BIOL CHEM 1992,267 (30) 21720 Cytochrome-P 450 arachidonic acid epoxyge- nase - regulatory control of the renal epox- ygenase by dietary salt loading.

Strijbos PJ, Hardwick Al, Relton JK, Carey F, Rothwell NJ*// l Univ Manchester, Dept Physiol Sci, Manchester Ml3 9FT, England AMER J PHYSIOL 1992,263 (4) Pl, E632 Inhibition of central actions of cytokines on fever and thermogenesis by lipocortin-1 in- volves CRF.

Beckman B.S. Despinasse BP, Spriggs I.// Tu- _ -- lane Univ, Sch Mid, Dept Pharmacol, 1430 Tulane Ave. New Orleans. La 70112, USA PR~~SO~EXP BIOL M~~1992,201(2) 169 Actions of lipoxins-A4 and lipoxinsB4 on signal transduction events in Friend erythro- leukemia cells.

Thomas DW, Vankuijk FJGM, Stephens RI*// ‘SRI Int, Div Life Sci, Menlo Pk, Ca 9402.5, USA ANAL BIOCHEM 1992,206 (2) 353 Quantitative determination of hydroxy fatty acids as an indicator of in vivo lipid peroxida- tion - oxidation products of arachidonic and docosapentaenoic acids in rat liver after expo- sure to carbon tetrachloride.

Choi D, Ward BL, Bostock RM’// *Univ Calif Davis, Dept Plant Pathol, Davis, Ca 95616, USA PLANT CELL 1992,4 (10) 1333 Differential induction and suppression of po- tato 3-hydrov-3-methylglutatyl coenxyme-A reductase genes in response to Phytophthora infestans and to its elicitor arachidonic acid.

Tence M, Cordier J, Glowinski J, Premont J// Coil France, INSERM, U 114, Neurophar- macol Lab, 11 PI Marcelin Berthelot, F- 75231 Paris 05, France EUR J NEUROSCI 1992,4 (10) 993 Endothelincvoked release of arachidonic

Kunievsky B, Bazan NG, Yavin E*// *Weir- mann Inst Sci, Dept Neutobiol, IL-76100

Rehovot, Israel J NEUROCHEM 1992,59 (5) 1812 Generation of arachidonic acid and dia- cyglycerol2nd messengers from polyphos- phoinositides in ischemic fetal brain.

5. PROSTAGLANDINS E AND F Schmid C, Schlapfer I, Waldvogel M, Zapf J, Froesch EIU/ Med Hsch Hannover. Zen&urn Chirurg, Abdominal & Transplantat Chirurg Klin, Konstanty Gutschow Str 8, W-8000 Han- never 61, FRG J BONE MINER RES 1992,7 (10) 1157 ProstaglandinE(2) stimulates synthesis of insulin-like growth factor binding protein-3 in rat bone cells in vitro.

Katz IA, Jee WSS, Joffe II, Stein B, Takira- wa M, Jacobs TW, Setterberg R, Lin BY, Tang LY, Ke HZ, Epstein S* et al// *Albert Einstein Med Ctr, No Div, Div Endocrinol & Metab. York & Tabor Rd. Philadelphia, Pa 19141, ‘USA J BONE MINER RES 1992.7 (101 1191 ProstaglandinE(2) alleviates c&sporin-A- induced bone loss in the rat.

Khoury SJ, Hancock WW, Weiner HI.// Har- vard Univ, Brigham & Womens Hosp, Sch Med, Dept Med, Ctr Neurol Dis, Multiple Sclerosis Unit, Boston, Ma 02115, USA J EXP MED 1992,176 (5) 1355 Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated wtih downregulation of inflammatory cytokines and differential upregulation of transforming growth factor-beta, interleukin-l, and prostaglandin-E expression in the brain.

Schmidley JW, Dadson J, Iyer RS, Salomon RG// Case Western Res Univ, Dept Neurol, Room S404,3395 Scranton Rd, Cleveland, Oh 44106, USA PROSTAGLAND LEUK ESSENT FATIY 1992,47 ( 2) 105 Brain tissue injury and blood-brain barrier ;g.eFg induced by injection of LGE2 or

Chen HW, Duitsman P, Cook L, Hendrich S* // *Iowa State Univ Sci & Technol, Dept Food Sci & Human Nutr, Ames, Ia 50011, USA PROSTAGLAND LEUK ESSENT FATTY 1992,47 ( 2) 143 Sex and dietary fat modulate hepatic prostaglandin-F-@alpha) in F344/N rats.

Vaillier D, Daculsi R, Gualde N/I Univ Bor- deaux 2, CNRS, URA 1456,146 rue Leo Saig- nat, F-33076 Bordeaux, France CANCER IMMUNOL IMMUNOTHER 1992,35 (6) 395 Effects of lipopolysaccharide on interleukin9- induced cytotoxic activity of murine spleno- cyte cultures - Role of prostaglandinE2 and interferons.

Roper RL, Phipps RP*// l Univ Rochester, Sch Med. Ctr Cant, Box 704,601 Elmwood Ave, Rochester, NY 14642, USA J IMMUNOL 1992.149 (9) 2984 ProstaglandinE2 and CAMP inhibit lympho- cyte-B activation and simultaneously pro- mote IgE and IgGl synthesis.

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Kimura J. Nakaiima Y, Ohmura T, Ito K, Ta- naka Y, I&h&&a M, Takahashi M, Matsue H. Ishimura H. Isai H et aI// Hokkaido Univ. Sch Med, Dept Anim Sci, Kita 15 Nishi 7, Kita ku, Sapporo, Hokkaido 060, Japan TRANSPLANT PROC 1992,24 (5) 1992 Changes in prostaglandin E2 during and after liver transplantation in pigs.

Koh II-II, Kim PCW, Chung SW, Waddell T, Wont PY. Gorczvnski R Levv GA*, Cohen Z // ;Tor&rto G&r Hasp, zod Elizabth St, GWE 3-538. Toronto. Ontario. Canada M5G

?&NSPLANTATION l992,54 (4) 592 The effects of 16,16 dimethyl prostaglandin- E2 theram alone and in combinations with low-dose+ cyclosporine on rat small intestinal transplantation.

Ke HZ, Li M, Jee WSS*// l Univ Utah, Sch Med, Div Radiobiol, Bldg 586, Sait Lake City, Ut 84112, USA BONE MINER 1992,19 (1) 45 Pmstaglandin-E.2 prevents ovariectomy-induced cancellous bone loss in rats.

Matsuo K, Kushima H, Noguchi M, Sakagu- chi Y, Fujiwara TN Shinshu Univ, Sch Med, Dept Plast & Reconstruct Surg, 3-l-l Asahi, Matsumoto, Nagano 390, Japan ANN PLASTIC SURG 1992,29 (4) 314 Continuous intraarterial infusion of pmstaglandin-El and heparin to extend and im- prove the survival of pedicled musculocuta- neous flaps through unusual routes - a dini- cal preliminaty report.

Grataroii R Vamecq J, Poupaert JH, Leonar- di J, Termine E, Lafont H, Nalbone G/l IN- SERM, Unite 130,18 Ave Mozart, F-13689 Marseille, France J LIPID MEDIATOR 1992,s (3) 227 Effects of dietary n-6/n-3 ratios on lipid and prostaglandinE2 metabolism in rat gastric mucosa.

Sun YO, Lu SB. Wang JF// Peoples Liberat Armygen Hosp,‘Dept-Orthopaeb, Beijing 100853. Peov1e.s R China CHIN MEd J 1992,105 (9) 742 In vitro and in vivo effects of PGE2 on ce- mentless fixation of implant.

Schimpl G, Sauer H, Deutsch J, Schober PH, Becker H/1 Gras Univ. Sch Med. Dent Pediat

- Surg, A-8010 Gras, Austria PEDIAT SURG INT 1992.7 16) 438 Efficacy of prostagiandin I?? and ursodeoxy- cholic acid after portoenterostomy in the prognostically unfavorable type-III biliary at- resia.

Mccoshen JA, Bose R, Embree JE// Univ Manitoba, Dept Obstet Gynecol & Reprod Sci, 59 Emily St, Winnipeg, Manitoba, Cana- da R3E lY9 SEMIN REPROD ENDOCR 1992,lO (3) 294 Uterine prolactin and labor - modulation by human chorionic gonadotropin affects pmstaglandin-(PG)-E2 and PGF2a production.

Ling BN, Kokko KE, Eaton DC// Emory Univ, Sch Med, Dept Med, Div Renal, 1364 Clifton Rd NE, Atlanta, Ga 38322, USA J CLIN INVESI- 1992,% (4) 1328 Inhibition of apical Na+ channels in rabbit cortical collecting tubules by basolateral pros- taglandinE2 is modulated by protein kinase- C.

Sorokin Y, Hallak M, Klein 0, Kalderon I, Abramovici II// Wavne State Univ. Hutzel Hasp, Sch Med, D&t Obstet & G&ml, Div Maternal Fetal Med, Detroit, Mi 48281, USA OBSI’ET GYNECOL 1992,80 (5) 788 Effects of induction of labor with prostaglandin-E2 on fetal breathing and body move- ments - controlled, randomized, double-blind study.

Borasio PG, Cervellati F, Fabbri EJ/ Univ Ferrara, lnst Gen Physiol, Via L Borsari 46, 144100 Ferrara, Italy NEUROSCI LEIT 1992,145 (1) 105 Sulmazole effects on PGE2 and D-AIa2-met- enkephalinamide modulation of cyclic AMP synthesis and neurotransmitter release in a sympathetic ganglion.

6. PROSTACYCLIN Smith JS, Wey HE, Leikauf GD, Baxter CS* 11 l Univ Cincinnati, Med Ctr, Dept Envi- mnm Hlth, 3223 Eden Ave, ML 56, Cincinna- ti, Oh 45267, USA CARCINOGENESIS 1992,13 (10) 1859 Carbaprostacyclin inhibits 12-O-tetradeca- noylphorbol-13-acetate @PA)-induced transformation in sensitive murine epidermal JB6 cells.

Yee ES, Hsieh WR// Dept Cardiovasc Surg, 311 Straight St, Cincinnati, Oh 45219, USA VASC SURG 1992,26 (8) 605 Modification of myocardial reperfusion by exogenous prostacyclin.

Erbrich AC, Church DJ, Vallotton MB, Lang U*// l Univ Geneva, Hop Cantonal, Dept Med, Div Endocrinol, 24 Rue Micheli Du Crest, CH-1211 Geneva 4, Switzerland AMER J PHYSIOL 1992,263 (4) Pl, E800 Regulation of pmstacyclin production by ICa2 + ]i and protein kinase-C in aortic smooth muscle cells.

7. THROMBOXANES Lasserre B, Huu AP, Navarrodelmasure C, Dossougbete V// lnst Physiol, 2 F Magendie, F-31400 Toulouse, France PROSIAGLAND LEUK ESSENT FATTY 1992,47 ( 2) 153 Binding of a thmmboxane-A(2) (lXA(2))/pmstaglandin-H(2) (PGHZ) receptor antagonist to rabbit and pig heart membrane protein.

Walsh SW, Wang YP, Kay HH, McCoy MC// Virginia Commonwealth Univ, Med Co11 Vir- ginia, Dept Obstet & Gynecol, Box 34, MCV Stn, Richmond, Va 23298, USA AMER J OBSIEI GYNECOL 1992,167 (4) 926 Low-dose aspirin inhibits lipid peroxides and thmmboxane but not prostacyclin in pregnant women.

Wang YP, Walsh SW’, Kay HH// *Virginia Commonwealth Univ, Med Co11 Virginia, Dept Obstet & Gynecol, Box 34, MCV Stn, Richmond, Va 23298, USA AMER J OBSIEI GYNECOL 1992,167 (4) 946 Placental lipid peroxides and thmmboxane are increased and ptostacyclin is decreased in women with preeclampsia.

Dim EM, Gabbe SG, Moore JW, Kniss DA*// *Ohio State Univ, Coil Med, Dept Obstet & Gynecol, Div Maternal Fetal Med, 16.54 Upham Dr, Menas Hall, Columbus, Oh 43210, USA

AMER J OBSIET GYNECOL 1992,167 (4) 1046 Study of thmmboxane and pmstacyclin metabolism in an in vitro model of lst-trimester human tmphoblast.

Ogletree ML, Okcefe EH, Durham SK, Rubin B, Aberg G// Bristol Myers Squibb Pharmaceut Rea Inst. Deut Pharmacol. Princeton, NJ 08543,‘USA J PHARMACOL EKP THER 1992,263 (1) 374 Gastmpmtective effects of thmmboxane receptor antagonists.

Santillandoherty P, Jassovictoria R, Sotresve- ga A, Iopezmedrano R Santibanez A, An- drade R, Arreola JL, Oimos R, Villaba J, Garcia D// lnst Nacl Enfermedades Resp, Dept Exptl Surg, Calrada Tialpan 4502, Tial- pan 14080, DF, Mexico TRANSPLANT PROC 1992,24 (5) 2022 Urinary thmmboxane 82 excretion during acute rejection in cyclosporine-treated experimental lung allotransplantation.

Polette A, Blache D*// *Hop Bccage, Bio- chim Lipoproteins Lab, F-21034 Dijon, France ATHEROSCLEROSIS 1992, % (2-3) 171 Effect of vitamin-E on acute iron load-poten- tiated aggregation, secretion, calcium uptake and thmmboxane biosynthesis in rat platelets.

Wikstmm E, Westlund P, Nicolaou KC, Dahlen SE// Kamlinska Inst, Dept Physiol, S- 10401 Stockholm 60, Sweden J LIPID MEDIATOR 1992,s (3) 205 Lipoxin All-induced release of thmmboxane in the guinea pig lung - studies of its characteristics using lipoxin M-methyl ester.

Faull AW, Gaskin H, Hadfield PS, Jessup R Russell K, Watkins WJ’, Wayne MI/ ‘ICI Pharmaceut PLC, Dept Chem 2, Mereside, Alderley Pk, Macclesfield SK10 4TG, Che- shire, England BIOORG MEDICINAL CHEM LEFIER 1992,2 (10 ) 1181 Dual-acting thromboxane receptor antagonist synthase inhibitors - heterocyclic wari- ations.

8. LEUKOTRIENES Boberg M, Pollare T, Siegbahn A, Vessby B’N ‘Univ Uppsala, Dept Geriatr, POB 2151, S-75002 Uppsala, Sweden EUR J CLIN INVEST 1992,22 (10) 645 Supplementation with n-3 fatty acids reduces triglycerides but increases PAI- in non-insulin-dependent diabetes-mellitus.

Nielsen GL, Faarvang KL, Thomsen BS, Te- glbjaerg KL, Jensen LT, Hansen TM, Ler- vang HH, Schmidt EB, Dyerberg J, Ernst I!.// Aalborg Hosp, Dept Rheumatol, Carsten Hauchsvej 11, DK-9000 Aalborg, Denmark EUR J CLIN INVEST 1992,22 (10) 687 The effects of dietaty supplementation with n-3 polyunsaturated fatty acids in patients with rheumatoid arthritis - A randomized, double blind trial.

Birch EE, Birch DC, Hoffman DR, Uauy R// Retina Fdn SW, 9900 N Cent Expy, Suite 400, Dallas, TX 75231, USA INVESI OPHTHALMOL VISUAL SC1 1992,33 ( 11) 3242 Dietary essential fatty acid supply and visual acuity development.

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Wuwang CY, Wang SL, Lim C, Milles M, Slomiany A, Slomiany BW Univ Med &

and colonic mum.

Dent New Jersey, New Jew Dent Sch. Res Ctr, Newark, Nj 07103, USi PROSTAG- LEUK ESSENT FATI-Y

Bell JG, Dick JR Sareent JR. Mcvicar AH // Univ Stirling, Sch Nat-&i, *RC, Aquat Biochem Unit. Stirlinn FK9 4LA. Scotland

1992,47 ( 2) 101 COMP BIOCiiEM P-mSIOL P? A 1992, Cigarette smoking reduces human salivary ei- 103 (2) 337 cosanoids. Dietary linoleic acid affects DhospholiDid

Lee HC, Yamaguchi M, Ikenoue T, Miyaka- wa I, Mori N// Miyazaki Med Coil, Dept Ob- stet & Gynecol, Kihara 5200, Miyazaki 88916, Japan PROSTAGLAND LEUK ESSENT FATIY 1992,47 ( 2) 117 Amniotic fluid embolism and leukotrienes - The role of amniotic fluid surfactant in leukotriene production.

Smuts CM, Kruger M, Vanjaarsveld PJ, Fin- cham JE, Schall R, Vandermelwe KJ. Be- nade AJill S African MRC, Natl P&gram Nutr Intelwnt, POB 19070, mrberg 7505, South Africa PROSTAGLAND LEUK ESSENT FAlTY 1992,47 ( 2) 129 Tbe influence of fish oil supplementation on plasma lipoproteins and arterial lipids in ver- vet monkeys with established atherosclerosis.

Williams LL, Kiecoltglaser JK, Horrocks LA, Hillhouse JT, Glaser IU/ Ohio State Univ, Med Ctr, Dept Pediat, 700 Childrens Dr, Col- umbus, Oh 43205, USA PROSTAGIAND LEUK ESSENT FATIY 1992,47 ( 2) 165 Quantitative association between altered plasma esterified omega-6 fatty acid proportions and psychological stress.

Deterding LI, Curtis JF, Tomer KB// NIEHS, Molec Biophys Lab, POB 12233, Res Triangle Pk, NC 27709, USA BIOL MASS SPECI-ROM 1992,21 (11) 597 Tandem mass spectrometric identification of eicosanoids - leukotrienes and hydroxyeicosatetraenoic acids.

Huanp: YS, Redden PR, Horrobin DF, Chur- chill S: Parker B, Ward RP, Mills DE // Efa- mol Res Inst. Kentville. NS. Canada B4N 4H8 BRIT J Nti 1992,& (2 j 337 Effects of repeated gestation and lactation on milk N-6 fatty acid composition in rats fed on a diet rich in 18/2n-6 or 18/3n-6.

Nozaki S, Matsuzawa Y, Hirano K, Sakai N, Kubo M, Tarui S// Osaka Univ, Sch Med, Dept Internal Med 2, Fukushima ku, Osaka 553, Japan INT J VITAM NUTR RES 1992,62 (3) 256 Effects of purified eicosapentaenoic acid ethyl ester on plasma lipoproteins in primary hypercholesterolemia.

Werner SA, Luedecke LO, Shultz TD’// ‘Washineton State Univ. DeDt Food Sci & Human I&tr, Pullman, $a 6164, USA J AGR FOOD CHEM 1992.40 (10‘) 1817 Determination of conjugated lin&eic acid content and isomer distribution in 3 cheddar- type cheeses - effects of cheese cultures, pro- cessing, and aging.

Gael RK, Tavares IA, Bennett A*// *Kings C&l, Sch Med & Dent, Rayne Inst, Dept Surg, 123 Coldharbour Lane, London SE9 9NU, England J PHARM PHARMACOL 1992,44 (10) 862 Effects of cupric chloride and tamrabhasma, a traditional Indian preparation of copper, on eicosanoid production by human gastric

fatty acid composition in he& and e&a- noid production by cardiomyocyte-s from at- lantic salmon (Salmo s-alar)

Roach PD, Dowling K, Balasubramaniam S, Illman RJ, Kambouris AM, Nestel PJ, Top- ping DU/ CSIRO, Div Human Nutr, POB 10041, Gouger St, Adelaide, SA 5000, Austra- lia ATHEROSCLEROSIS 1992, % (2-3) 219 Fish oil and oat bran in combination effec- tively lower plasma cholesterol in the rat.

Espersen GT, Ngrunnet N, Lervang HH, Nielsen GL. Thomsen BS. Faarvann KL. Dyerberg J,‘Emst E// Stroybergsveil9, DK- 9000 Aalborg, Denmark CLIN RHEUMATOL 1992,ll (3) 393 Decreased interleukin-l-beta levels in plasma from rheumatoid arthritis patients after dietary supplementation with n-3 polyunsaturated fatty acids.

Nielsen H// Aarhus Univ, Inst Med Biochem, DK-8000 Aarhus. Denmark J SC1 FOOD A6R 1992,59 (4) 559 n-3 polyunsaturated fish fatty acids in a fish- oil-supplemented bread.

Neu IS, Wildfeuer A, Mallinger J, Mehlber U/ Stadt Krankenhaus Sindelfingen, Neurol Abt, Arthur Gruber Str 70, W-7023 Sindelfin- gen, FRG ARZNEIN-FORSCH-DRUG RES 1992,42- 2 (9) 1083 Suppression of experimental autoimmune encephalomyelitis by a new specific inhibitor of leukotriene biosynthesis.

Depre M, Margolskee DJ, Hsieh JYK, Van- hecken A, Buntinx A, Delepeleire I, Rogers JD, Deschepper PJ*// *Caiholic Univ - Leuven. Sch Med. Dent Pharmacol. Campus Gasthuisberg O&N, ierestr 49, B-&O0 I&I- vain, Belgium EUR J CLIN PHARMACOL 1992,43 (4) 427 Plasma drug profiles and tolerability of MK- 571 (L-660,711), a leukotriene D4 receptor antagonist, in man.

Depre M, Margolskee DJ, Vanhecken A, Hsieh JSY, Buntinx A, Deschepper PJ’, Ro- gers JDN *Catholic Univ Leuven, Sch Med, Dept Pharmacol, Hercstr 49, B-3000 Lou- vain, Belgium EUR J CLIN PHARMACOL 1992,43 (4) 431 Dose-dependent kinetics of the enantiomers of MK-571, and LTD4-receptor antagonist.

Lane GE, Deutsch E, Bove AA// Mayo Clin Jacksonville, Div Cardiovasc. 4500 San Pablo Rd, Jacksonville, Fl 32224, USA CORONARY ARTERY DIS 1992,3 (10) 973 Leukotriene-mediated coronary vasoconstriction in the closed-chest dog - augmented ar- teriolar vasoconstriction after proximal endothelial damage.

Nagai H, KGa A// Gifu Pharmaceut Univ, Miura T, lnagaki N, Goto S, Yoshida K,

Dept Pharmacol, 5-6-l Mitahorahigashi, Gifu 502, Japan

EUR J PHARMACOL 1992,221(2-3) 333 Leukotriene receptors in the skin of rats dif- fer from those of mouse skin or rat stomach strip.

Zamboni R, Fklley M, Champion E. Cha- rette L, Dehaven k, I&enett;R, Gauthier JY, Jones m Leger S, Masson P et al// Merck Fro& Ctr Therapeut Res, POB 1005, Pointe Claire. Quebec. Canada H9R 4P8 J MED CHEti 1992,& (21) 3832 Development of a novel series of sty-rylqui- noline compounds as high-affinity leukotriene-D4 receptor antagonists - synthetic and structure activity studies leading to the discovexy of (+/-)3-[[[3-[2-(7shlom-2qui- nolinyl) -(E)-ethenyl]phenyl]([3-(dimeth ylamino)3_oxopmpyl]thio]methyl]thio]p m- pionic acid.

Holden WE, Bumham EM, Lee MA, Bagby SP N Portland Vet Affairs Med Ctr, Med Serv, 3710 SW US Vet Hosp Rd, Portland, Or 97207, USA AMER J PHYSIOL 1992,263 (4) Pl, l&4 Influence of growth oxygen level on eicosanoid release from lung endothelial cells during hypoxia.

Prescott SM// Univ Utah. Deut Med. Bide 500 CVRTI, Salt Lake City, tit 8411i, USI AMER J CLIN NUTR 1992.56 141 S. S801 What are the effects of diet& fa& acid modification on platelet eicosanoid metabolism, platelet-activating factor, and platelet function - how might these metabolic alter- ations influence thrombosis.

Harker LA// Emory Univ, Sch Med, Div He- matol & Oncol, Drawer AR, Atlanta, Ga 30322, USA AMER J CLIN NUTR 1992,56 (4) S, S817 What are the effects of dietary n-3 fatty acids on vascular thmmbus and lesion formation in nonhuman primates.

Shimizu T, Beijer E, Standvik B// Gothen- bure Univ. DeDt Paediat. S41124 Gothen- burg, Sweden _ J PEDIAT GASIROENTEROL NUTR 1992.15 (4) 461 Capacity bf small intestinal mucosa to pm- duce leukotrienes B-4 and C4 in children with celiac disease (Letter)

Branski D, Weidenfeld J// Shaare Zedek Med Ctr, Dept Pediat, Jerusalem, Israel J PEDIAT GASTROENTEROL NUTR 1992, 15 (4) 461 Capacity of small intestinal mucosa to pm- duce leukotriene B-4 and C4 in children with celiac disease (Reply)

Dufh 0, Menez JF, Leonard BE// Fat Med Bresi, !&XV Biochim, F-29285 Brest, France DRUG ALCOHOL DEPENDENCE 1992. 31 (1) 85 Attenuation of the effects of chronic ethanol administration in the brain lipid content of the developing rat by an oil enriched in gamma-linolenic acid.

Brenner T, Boneh A, Shohami E, Abramsky 0, Weidenfeld JN Hadassah Univ Hosp, Dept Neuml, POB 12000, Ein Karem, Jerusa lem, Israel J NEUROIMMUNOL 1992,40 (2-3) 273 Glucocorticoid regulation of eicosanoid pm- duction by glial cells under basal and stimulated conditions.

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9. PLATELET-ACTIVATING FACTOR Ichimaru T, Tai HI-I’// l Univ Kentucky, Coil Pharm, Div Med Chem & Pharmaceut, Lex- ington, Ky 40536, USA PROSTAGLAND LEUK ESSENT FATIY 1992,47 ( 2) 123 Alteration of platelet activating factor (PAF) metabolism in rat pulmonary alveolar macrophages and plasma by cigarette smoking.

Rvan JP. Oneill C. Ammit AJ, Roberts CG // Royal N.Shore Hasp, Human Reprod Unit, St Leonards. NSW 2865. Australia REPROD FERT DEVELOP 1992,4 (4) 387 Metabolic and developmental responses of preimplantation embryos to platelet activating factor (PAF)

Pike IL, Ammit AJ, Oneill U/ Royal N Shore Hosp, Human Reprod Unit, St Leo- nards, NSW 2865, Australia REPROD FERT DEVELOP 1992,4 (4) 399 Actions of platelet activating factor (PAF) on gametes and embryos - Clinical aspects.

Sobhani I, Denixot Y, Vissuzaine C, Vatier J, Benveniste J, Lewin MJM, Mignon M// CHU Bichat, Serv Hepatogastroenterol, 46 Rue Henri Huchard, F-74877 Paris 18, France DIGEST DIS SC1 1992,37 (10) 1583 Significance and regulation of gastric secretion of platelet-activating factor (PAF- acether) in man.

Foster AP, Lees P, Cunningham FM// Royal Vet Coil, Dept Vet Basic Sci, Hawkshead Lane, N .Mymms AL9 7TA, Herts, England RES VET SC1 1992.53 (2) 223 Platelet activating factor.& a mediator of equine neutrophil and eosinophil migration in vitro.

Qian CG, Liu CT*, Peters CJ// *USA, Med Res Inst Infect Dis, Dept Physiol & Pharma- col, Div Toxicol, Ft Detrick, Frederick, Md 21702, USA J LIPID MEDIATOR 1992,5 (3) 261 Increased platelet-activating factor (PAF) concentrations in hearts and lungs of pi- chinde virus-infected guinea pigs.

Kudolo GB, Harper MJK*// l Univ Texas, Hlth Sci Ctr, Dept Obstet & Gynecol, 7703 Floyd Curl Drive, San Antonio, TX 78284, USA J LIPID MEDIATOR 1992,5 (3) 271 Pregnancy-associated remodeling of rabbit endometrial platelet-activating factor-receptors.

Burgers JA, Akkerman JWN’// l Univ Hosp Utrecht, Dept Haematol, Huispostnr G03- 647, POB 85500,3508 GA Utrecht, Nether- lands J LIPID MEDIATOR 1992,5 (3) 289 Effect of platelet agonists on the binding of platelet-activating factor to human platelets.

Eldar M, Lysko PG, Schulhoff N, Gagnon RC, Feuerstein G, Sham J// Chaim Sheba Univ Ctr, Inst Heart, IL-52621 Tel Ha- shomer, Israel J LIPID MEDIATOR 1992,s (3) 313 Effects of coronary angioplasty on plasma platelet-activating factor in man.

Kester M, Thomas CP, Wana J. Dunn MJ// Case Western Reserve. Unit,-&% Med, Dept Med. Cleveland. Oh 44106. USA J CELL PHYSIOL1992,153 (2) 244

Platelet-activating factor stimulates multiple signaling pathways in cultured rat mesangial cells.

Denizot Y, Chaussade S, Nathan N, Coutu- rier D, Benveniste J// Fat Med Limoges, IN- SERM 8883,2 rue Docteur Marcland, F- 87825 Limoges, France EUR J GASIROENTEROL HEPATOL 1992,4 (11) 871 PAF-acether and the gastrointestinal tract.

Reme C, Wei Q, Munr K, Jung H, Doly M, Droylefaix MT// Univ Hosp Zurich, Dept Ophthalmol, CH-8091 Zurich, Switzerland GRAEF ARCH CLIN EXP OPHTHAL 1992,230 (6 ) 580 Light and lithium effects in the rat retina - modification by the PAP antagonist BN 52021.

Vleeming W, Werner J, Pomius AJ// Univ Utrecht, Fat Pharm, Dept Pharmacotherapy, POB 80082,3508 TB Utrecht, Netherlands J CARDIOVASC PHARMA COL 1992,20 (5) 790 Modulation of antigen-induced and ischemia- induced effects by the platelet-activating factor antagonist WEB-2986 in isolated sensitized rat hearts.

Sieunarine K, Lawrencebrown MM, Good- man MA, Prednergast FJ, Rocchetta S// Univ Nedlands, Sir Charles Gairdner Hosp, Dept Surg, Nedlands, WA 6009, Australia VOX SANG 1992,63 (3) 168 Plasma levels of the lipid mediators, leukotriene B4 and lyso platelet-activating factor, in intmopcrative salvaged blood.

Chu M, Pate1 MG, Gullo VP, Truumees I, Puar MS, Mcphail AT// Schering Plough Carp, Res Inst, 60 Orange St, Bloomfield, NJ 07003, USA J ORG CHEM 1992,57 (22) 5817 Sch47918 - a novel PAP antagonist from the fungus Phoma sp.

11. RELATED ENZYMES Ronkko S// Univ Kuooio. Deot Anat. POB 1627, SF-70211 Kuopib, Finland IN-I J ANDROL 1992.15 (5) 3W Purification and character&ion of phos- pholipaseA2 from bovine prcetate.

Pruranski W, MacKensen A, Engelhardt R, Stefanski E, Vadas P// Univ Toronto, Welles- ley Hasp, Inflammat Res Grp, 160 Wellesley St E, Room 104 Jones Bldg, Toronto, Onta- rio, Canada M4Y 133 J IMMUNOTHER 1992,12 (4) 242 Induction of circulating phospholipaseA2 activity by intravenous infusion of endotoxin in patients with neoplasia.

Aldigier JC, Cook J, Delebassee S, Guibert F, Touchard G, Juzan M, Gualde N*// l CHU Dupuytren, Dept Nephrol, F-87033 Li- moges, France PROSI-AGLAND LEUK ESSENT FATIY 1992,47 ( 2) 159 NZB/NZW-Fl mouse nephritis and immune response arc not changed by treatment with a 15-lipoxygenase derivative.

Peters AR Dekker N, Vandenberg L, Boelens R, Kaptein R’, Slotboom AJ, De- haas GH// l Univ Utrecht, Bijvoet Ctr Biomo- let Res, POB 80054,3584 CH Utrecht, Netherlands BIOCHEMISIRY-USA 1992,31 (41) 10024

Conformational changes in phospholipase- A2 upon binding to micellar interfaces in the absence and presence of competitive inhibitors - A H-l and N-15 NMR study.

Wijkander J, Sundler R*// l Univ Lund, Dept Med & Physiol Chem, POB 94, S-22100 Lund, Sweden FEBS LETT 1992,311(3) 299 Regulation of arachidonate-mobilizing phos- pholipaseA2 by phosphorylation via protein kinase-C in macrophages.

Lathrop BK, Biltonen RL*// l Univ Virginia, Hlth Sci Ctr, Dept Biochem, Charlottesville, Va 22998, USA J BIOL CHEM 1992,267 (30) 21425 Calcium and magnesium dependence of phos- pholipaseA2catalyxed hydrolysis of phos- phatidylcholine small unilamellar vesicles.

Holtzman MJ, Turk J, Shomick LP// Wash- ington Univ, Sch Med, Dept Med, 660 S Eu- clid Ave. Box 8052. St Louis. MO 63110. USA J BIOL CHEM 1992,267 (3b) 21438 ’ Identification of a pharmacologically distinct prostaglandin-H synthase in cultured epithelial cells.

Meshulam T, Herscovitr H, Casavant D, Ber- nardo J, Roman R, Haugland RP, Strohmeier GS, Diamond RD, Simons ER*// *Boston Univ, Sch Med, Dept B&hem, Bos- ton, Ma 02118, USA J BIOL CHEM 1992,267 (30) 21465 Flow cytometric kinetic measurements of neutrophil phospholipase-A activation.

Wilkes BM, Hollander AM, Sung SY, Mento PF// N Shore Univ Hosp, Dept Med, Div Ne- phrol & Hypertens, 300 Community Dr, Man- hasset, NY 11030, USA AMER J PHYSIOL 1992,263 (4) Pl, E718 Cyclooxygenase inhibitors blunt thromboxane action in human placental arteries by block- ing thromboxane receptors.

Timar J, Chen YQ, Liu B, Barax R, Taylor JD, Honn KV’// *Wayne State Univ, Dept Radiat Oncol, Div Cant Biol, 431 Chem, De- troit, Mi 48292, USA INT J CANCER 1992,52 (4) 594 The lipoxygenase metabolite 12(s)-HEIE promotes-alphallbbeta3 integrin-mediated tumor-cell spreading on fibronectin.

Brooks DW, Schmidt SP, Dyer RD, Young PR Carter GW// Immunosci Res, Dept 47K, Abbott Labs, Abbott Pk, II 60064, USA BIOORG MEDICINAL CHEM LEPI’BR l!xz,2 (10 ) 1309 Structural analysis of 2-aryl-1,3dione compounds as inhibitors of 5-lipoxygenase.

Thomas SB, Surber BW, Fitzeerald M// Ab- bott Labs, Dept Drug Metabrl Abbott Pk Rd, N Chicago, II 60064, USA J CHROMATOGR 1992,623 (2) 390 Preparative separation and analysii of the enantiomers of [C-14]zileuton, a 5-lipoxygenase inhibitor.

Piec G, Jakob A*// l Univ Base& Dept Biochem, Vesalgasse 1, CH-4051 Bascl, Swit- zerland BIOCHIM BIOPHYS ACTA 1992,llll (1) 27 Vasopressin stimulation of vanadate-sensitive Na + transport by liver plasma membrane vesicles - evidence for regulation via phospholipase-C and protein kinase-C activities.

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12. PRODUCTION AND RELEASE Lee M, Aldmd K, Lee E, Prince MD, Feld-

Albrightson CR, Nambi P, Zabkopotapovich man M// Dept Vet Affairs Med Ctr. 4500 S

B, Dytko Cl, Groom T// Smithkline Beecham Lancaster Rd, Dallas, TX 75216, USA Pharmaceut, Dept Pharmacol, I521, POB GASIROENTEROLOGY 1992.103 (5) 1467

1539, King of Prussia, Pa 19406, USA Importance of gastric acid in gastric ul& for- J PHARMACOL EXP THER 1992,263 (1) mation in rabbits with antibody-induced pros- 404 taglandin deficiency. Effect of thrombin on proliferation, contraction and prostaglandin production of rat glomendar mesangial cells in culture.

14. PROSTAGLANDINS IN MEDICINE

Goda Y, Fiuchi F, Shibuva M, Sankawa U* N l Univ Tokyo, Fat Pharmaceut Sci, 73 1 Honno. Bunkvo ku. Tokvo 113. Janan CHEM PHARM BULLTOICYO-1992,40 (9) 2452 Inhibitors of prostaglandin biosynthesis from Dalbergia odorifera.

Tancharoen S, Jones RM, Angus PW, Mi- chell ID, Mcnicol L, Hardy IU// Austin Hosp Natl Liver Transplant Univ, Heidelberg, Vie 3084, Australia TRANSPLANT PROC 1992,24 (5) 2248 Prostaglandin-El therapy in orthopic liver transplantation recipients - indications and outcome.

Roy AC, Ratnam SS// Nat Univ Singapore Hosp, Dept Obstet & Gynaecol, Lower Kent Ridge Rd, Singapore 0511, Singapore MOL REPROD DEV 1992,33 (3) 303 Biosynthesis of prostaglandins by human spermatozoa in vitro and their role in acro- some reaction and fertilization.

13. EFFECTS Chen J, Woodward DF*// *Allergan Pharma- ceut Inc, Discovery Res LSOA, 2525 Dupont Dr, POB 19534, Irvine, Ca 92713, USA 1NVEST0PHTHAL MOL VISUAL SC1 1992,33 ( 11) 3195 Prostanoid-induced relaxation of precon- tracted cat ciliaIy muscle is mediated by EP2 and DP receptors.

Spisni E, Manica F, Tomasi V// Univ Bolog- na, Dept Exptl Biol, 8 Via Belmeloro, I- 40126 Bologna, Italy PROSTAGLAND LEUK ESSENT FATI-Y 1992,47 ( 2) 111 Involvement of prostanoids in the regulation of angiogenesis by polypeptide growth factors.

Stewart P, Spiby H, Greer I// No Gen Hosp, Dept Obstet & Gynaecol, Sheffield S5 7AU, England BRIT J OBSIEI GYNAECOL 1992,99 (10) 861 Role of prostaglandin in the management of prelabour rupture of the membanes at term (Letter)

Word R4, Kamm KE, Casey MU/ Univ Texas, SW Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Dallas, TX 75235, USA J CLIN ENDOCRINOL METAB 1992.75 (4) 1027 Contractile effects of prostaglandins, oxytocin, and endothelin-1 in human myome- trium in vitro - refractoriness of myometrial tissue of pregnant women to pmstaglandin- E2 and prostaglandinF2alpha.

Mamett U/1 Vanderbilt Univ Med Ctr. Sch Med, Ctr Molec Toxicol, Dept B&hem, AB Hancock Jr Mem Lab Cant Res, Nashville, Tn 37232, USA CANCER RES 1992,52 (20) 5575 Aspirin and the potential role of pmstaglandins in colon cancer.

Neiko EM, Mishchuk VG, Botsiurko VI// lvano Frankovsk Med Inst, Chair Internal Med 2, Ivano Frankovsk, Ukraine VRACH DEL0 1992 (7) 30 State of immunity and level of prostaglandins in gastritis-B (Russian)

15. PROSTAGLANDINS AS DRUGS Fukushima R, Gianotti L, Alexander JW*, Pyles T// l Univ Cincinnati, Med Ctr, Dept Surg, DivTransplant, 231 Bethesda Ave, Cin- cinnati, Oh 45267, USAc ANN SURG 1992,216 (4) 438 The degree of bacterial translocation is a determinant factor for mortality after bum injury and is improved by prostaglandin analogs.

Pollak R, Knight R, Mozes MF, Maddux M, Veremis S. Vanburen C, Lewis R Scott E, Cole M, Hyndman V et al// Univ Illinois, Dept Surg, Div Transplantat, Box 6998, M-C 958, Chicago, II 60680, USA AMER J KIDNEY DIS 1992,20 (4) 336 A trial of the prostaglandin-El analogue, eni- soprost, to reverse chronic cyclosporine-associated renal dysfunction.

Leike J, Huhn U// Mittenwalder Str 22, O- 1152 Berlin. FRG BERL MUN TIERARZTL WO- CHENSCHR 1992.105 (10’) 345 Investigations on the &ch&tization of par- turition in sows with combined treatment with cloprostenol jenapharm and depotocin spofa (German)

Fretland DJ, Widomski DL, Anglin CP, Walsh RE, Levitt S, Gasiecki AF, Collins PW// Searle Res & Dev, Dept lmmunoin- flammatory Dis Res, 4901 Searle Pkwy, Skokie, II 60077, USA INFLAMMATION 1992,16 (6) 623 Mucosal protective activity of ptostaglandin analogs in rodent colonic inflammation.

Holm L, Jagare A// Univ Uppsala, Dept Physiol & Med Biophys, Box 572, S-75123 Uppsala, Sweden AMER J PHYSIOL 1992,263 (4) Pl, G446 Role of prostaglandins in regulation of gastric mucosal blood flow and acid secretion.

16. INHIBITORS OF SYNTHESIS Weinblatt ME, Kremer JM, Coblyn JS, Helf- gott S, Maier AL, Petrillo G, Henson B, Rubin P, Sperling R// Harvard Univ, Brig- ham & Womens Hosp, Sch Med, Dept Rheu- matol & Immunol, 75 Francis St, Boston, Ma 02115, USA J RHEUMATOL 1992,19 (10) 1537 Zileuton - a 5lipoxygenase inhibitor in rheumatoid arthritis.

Kanzik I, Cakici I, Ersoy S, Ark M, Abacio- glu N, Zengil H// Gaxi Univ, Fat Pharm, Dept Pharmacol, 06330 Etiler, Turkey

PHARMACOL RES 1992,26 (3) 305 Effects of qclooxygenase and lipoxygenase in hibitors on digoxin-induced arrhythmias and haemodynamics in guinea-pigs.

Lasfargues JJ, Saffar JL*// *Univ Paris 05, Fat Chirurg Dent, Biol & Biomat Milieu Buccal & Osseux Lab, 1 rue M Amoux, F- 92120 Montrouge, France ANAT REC 1992,234 (3) 310 Effects of prostaglandin inhibition on the bone activities associated with the sponta- neous drift of molar teeth in the rat.

18. CHEMICAL SYNTHESIS Witkowski S, Rao YK, Premchandran RI-I, Halushka PV, Fried J’// *Unit Chicago, Dept Chem, Chicago, II 68637, USA J AMER CHEM SOC 1992,114 (22) 8464 Total synthesis of (+)-lO,lOdifluorothrom- boxaneA2 and its 9,ll and 15 stereoisomers.

Kanger T, Lopp M’, Muraus A, Lohmus M, Kobxar G, Pehk T, Lille U// *Estonian Acad g’,:“,’ Chem, Akad Tee 15, Tallinn 200108,

SYNTHESIS-SI-UTIGART 1992 (10) 925 Synthesis of a novel, optically active 15-non- steroidogenic carbaprostacyclin.

Ono N, Tsuboi M, Okamoto S, Tanami T, Sato F’// *Tokyo Inst Technol, Dept Biomo- let Engn, Ookayama, Meguro ku, Tokyo 152, Japan CHEM LETI 1992 (10) 2095 Synthesis of ally1 ester of prostaglandin-E and the conversion of the ally1 ester moiety into carboxylic acid by chemical method - A highly practical synthesis of natural PGEl and limaprost.

19. TECHNIQUES Zublke CE, Anthuber M, Pratschke E. Merkle R, Briegel J// Klinikum Grosshadem, Chirurn Klin, Rardinominster 15. W-8000 Munich 70, FRG TRANSPLANT PROC 1992,24 (5) 1985 Color flow Doppler imaging during epopros- tenol (PG12) therapy of primaty nonfunction following liver transplantation.

The bibliography which sppesrs in this journal is also available on subscription, on a fortnightly basis, from Sheffteld University Biomedical Information Service, ShetIield SIO 2TN. UK. It is entitled ‘Prostaglandins - Biology’ (ISSN 0142-8284) and costs f76.00 (also available on diskette at f60.00).

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monthly prostaglandin bibliography prepared by the university of sheffield biomedical information...

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