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    MONSOONMONSOON

    DISEASESDISEASES

    Dr. K.V. PRABHAKARANDr. K.V. PRABHAKARAN

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    Common diseases during monsoon

    Leptospirosis

    Dengue fever

    Chikungunya

    Viral hepatitis

    Diarrhea

    Common cold

    Typhoid fever etc..

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    Leptospirosis (Rat fever)

    Caused by Leptospira (diff serotypes)

    L.icterohaemorrhagiae-Weils disease

    Some serotypes are harmless

    Leptospirosis varies from asymptomaticillness to severe disease and may be fatal

    too.

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    Leptospires are spiral bacteria(6-20micronsx0.1micron)

    Actively motile

    With one both ends hooked

    Usually seen by dark ground m/e

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    Where do Leptospires thrive Every mammal has the potential

    to become carrier.

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    Infected animals may not develop the

    disease but become long term carriers

    They harbour leptospires in theirkidneys and shed in urine,

    contaminating the environment

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    Leptospires can survive for weeks inwater or mud.

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    How does man get infected ??

    by direct or indirect contact with

    infected urine,tissues or secretions.

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    Leptospira gain entry through

    Small areas of damage on the skin or

    via mucus membranes.

    Rarely enters through waterloggedskin

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    Infection more common in certain

    occupational groups

    Farmers

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    Slaughter house workers

    Veterinarians etc

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    Flooded roadsFlooded roads

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    However It is not spread by animal bites or

    insect vectors

    Man to man spread (very rare)

    Congenital leptospirosis rarely occur

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    ClinicalClinical featuresfeatures

    AsymptomaticAsymptomatic

    Simple fever, body acheSimple fever, body ache

    JaundiceJaundice

    severe fatal illness with renal failuresevere fatal illness with renal failure

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    Laboratory diagnosisLaboratory diagnosis

    Detection of antibodies to leptospiraDetection of antibodies to leptospira(Igm)(Igm)

    Dark ground m/eDark ground m/e

    Culture of bacteriaCulture of bacteria

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    PreventionPrevention

    Rodent controlRodent control Appropriate waste disposalAppropriate waste disposal

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    Use of protective foot wear

    Cover cuts and abrasions Appropriate disinfection of

    contaminated water

    Vaccination of livestock pets

    Antimicrobial prophylaxis

    (doxycycline) in high risk exposurecases.

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    Dengue fever (break bone fever)Dengue fever (break bone fever)))

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    Highest incidence in SE Asia, India etc

    Dengue from Swahili Ki denga pepo(sudden seizure by demon)

    Caused by dengue virus (4 serotypes)

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    Dengue fever is transmitted byDengue fever is transmitted by

    Bite ofBite of A. aegyptiA. aegypti mosquitoesmosquitoes

    rarelyrarely A albopictusA albopictus..

    Day biting mosquitoDay biting mosquito

    Abundant in and around habitationAbundant in and around habitation

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    Dengue viruses are transmitted fromDengue viruses are transmitted from

    person to person by Aedes mosquitoes.person to person by Aedes mosquitoes.

    (mosquito can infect another person only 3(mosquito can infect another person only 3--10 day after10 day after

    blood meal)blood meal)

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    Why more dengue following rainfallWhy more dengue following rainfall

    Peak breeding timePeak breeding time

    Aedes mosquitoes breed in smallAedes mosquitoes breed in small

    collection and puddles of watercollection and puddles of water

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    Coconutshells DiscardedtyresCoconutshells Discardedtyres

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    Incubation periodIncubation period 22--7 day7 day Simple dengue feverSimple dengue fever Complicated dengue fever withComplicated dengue fever with

    hemorrhageshemorrhages

    Clinical features

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    Laboratory diagnosisLaboratory diagnosis

    Antibodies to dengue virusAntibodies to dengue virus

    IgM and IgG antibodiesIgM and IgG antibodies

    ELISA testELISA test

    Immunochromatographic testImmunochromatographic test

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    Control mosquitoControl mosquitopopulationpopulation

    Patients withPatients with

    suspected denguesuspected dengueshould beshould be

    preventedprevented

    from mosquitofrom mosquito

    bitesbites

    (under mosquito(under mosquitonet)net)

    Prevention & ControlPrevention & Control

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    Infection is rather spread by

    movement of personsand not much of mosquitoes

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    Viral hepatitisViral hepatitis

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    Man gets Infected byMan gets Infected by

    Ingestion of contaminated water,Ingestion of contaminated water,food (Shell fish) or milk .food (Shell fish) or milk .

    Over crowding and poor sanitationOver crowding and poor sanitation

    favors spreadfavors spread

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    Viral hepatitisViral hepatitis

    Virus multiplies in the intestinesVirus multiplies in the intestines

    through bloodthrough blood

    Reaches liverReaches liver

    HepatitisHepatitis

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    Contd..Contd..

    Virus is shed in feces of infectedVirus is shed in feces of infected

    personspersons

    Contaminates water and foodContaminates water and food

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    Prevention& ControlPrevention& Control

    Improved sanitary practiceImproved sanitary practice

    (prevention of fecal contamination of(prevention of fecal contamination of

    water and food )water and food )

    Effective vaccine is available forEffective vaccine is available forhepatitis A (Two dose 1M)hepatitis A (Two dose 1M)

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    Hepatitis E Infection is generallyHepatitis E Infection is generally

    mild.mild.

    HoweverHowever

    It has 20It has 20--40% fatality rate in40% fatality rate in

    pregnant womanpregnant woman

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    Lab Diagnosis of hepatitisLab Diagnosis of hepatitis

    Detection of Ab to Hep A and Hep EDetection of Ab to Hep A and Hep E

    Liver Function TestLiver Function Test

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    Enteric fever (Typhoid)Enteric fever (Typhoid)

    Occurs throughout the yearOccurs throughout the year

    Seasonal variations may occurSeasonal variations may occur

    Caused byCaused by Salmonella typhiSalmonella typhi &&

    paratyphiparatyphi A,B&CA,B&C

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    S

    ource of InfectionS

    ource of Infection

    A patient or a carrier.A patient or a carrier.

    Mode of infectionMode of infection

    Via contaminated water ,Milk & foodVia contaminated water ,Milk & food

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    Lab DiagnosisLab Diagnosis Culture of organisms fromCulture of organisms from

    blood,feces etcblood,feces etc

    Serological test for detection of AbSerological test for detection of Ab--

    WI

    DAL testWI

    DAL test

    ControlControl Hygienic measuresHygienic measures

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    DiarrheaDiarrhea

    In tropical countriesIn tropical countries

    Bacterial and protozoal diarrhea tendBacterial and protozoal diarrhea tendto occur in wetter seasonto occur in wetter season

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    BacterialBacterial

    CholeraCholera -- Via contaminated waterVia contaminated water Rice water stoolsRice water stools

    May be rapidly fatalMay be rapidly fatal

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    TreatmentTreatment

    Prompt rehydration is essentialPrompt rehydration is essential ORS (Oral rehydration solution)ORS (Oral rehydration solution) I/v fluids if necessaryI/v fluids if necessary

    Antibiotics like doxycyclineAntibiotics like doxycycline

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    Other pathogens

    Entamoeba Giardia

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