molecular and biomedical sciences at the university of nebraska-lincoln
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Molecular and Biomedical Sciences at the University of Nebraska-Lincoln
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Areas of Strength at UNL
MicrobiologyVirologyBacteriology
Redox BiologyBiochemistry
Vet Biomedicine
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MICROBIOLOGY at UNL
HIVHSVEBVKSHVVSVPRRSVHPVBacteriaFungi
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Funded by NIH Grant Number P20 RR15635 from theCOBRE Program of the National Center for ResearchResources
Anisa Angeletti Herpesvirus replication and host shutoffPeter Angeletti Human papillomavirus replicationRoy French Molecular biology of wheat virus diseasesClinton Jones Latency of alpha-herpesviruses, apoptosisEugene Martin Extreme halophiles, cyanophagesJack Morris Plant virology and biotechnologyFernando Osorio Animal virus pathogenesisAsit Pattnaik Gene expression of RNA virusesJames VanEtten Molecular characterization of algal virusesRobert Weldon Retrovirus assembly & pathogenesisCharles Wood HIV & herpesvirus molecular pathogenesisLuwen Zhang Herpes virus latency; interferonTom Petro Theilers Virus
Nebraska Center for Virology
40 Members on 3 campuses
UNL
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Funded by Grant P20RR15635 from the COBRE of the National Center for Research Resources$10,950,000/ 5yrs (2005-2010)
Extramural Funding by NCV members since year 2000 Over 39 million (PHS funding) since incept.
NIH Graduate Student and Postdoc Training Grant T32 - Training grant in Virology (UNL)
Fogarty International Training Grant $2, 100,000
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New Virology Building
Groundbreaking October 4th, 2006
Ken Morrison Research Building
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What’s Going on in the Beadle Center?
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In the Beadle Center
BiologyNebraska Center for VirologyBiochemistryCenter for Redox BiologyPlant ScienceBiotech Center
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Dr. James Alfano Dr. Marjorie LouDr. Ruma Banerjee Dr. Stephen RagsdaleDr. Joseph Barycki Dr. Ashraf RazaDr. Donald Becker Dr. George RozanskiDr. Liang-cheng Du Dr. Harold SchultzDr. Howard Gendelman Dr. Greg SomervilleDr. Vadim Gladyshev Dr. Julie StoneDr. Jonathan Kipnis Dr. Mark ThomasDr. Jaekwon Lee Dr. Mark WilsonDr. Ming-Fong Lin
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Microscopy Core Facility
Dr. Joe Zhou, Director
• microscopy imaging systems • technical support in bio-imaging • state-of-the-art equipment
three new electron microscopesa BioRad MRC1024ES confocal laser scanning microscopetwo advanced fluorescence microscopes with video
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Biosafety Level 3 Facilities
Live HIV and other virus studies
East Campus
Soon to be commissioned
Beadle Center
Ken Morrison Building
Future
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Flow Cytometry
Danielle Shea
Director: Dr. Charles Kuszynski
Beadle
East Campus
2 Locations:
Facscalibur
Bead-Array
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UNL Genomics Facility
Gene-chipsDNA SequencingHybridization
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Structural/Protein Core UNL Department of Chemistry Director: Dr. Ronald Cerny
• Exact Mass Measurement – Electron Ionization MS• Low Resolution Fast Atom Bombardment (FAB) MS• Exact Mass Measurement – FAB MS• Direct Injection (single component) Electrospray Ionization (ESI)• Liquid Chromatography – Mass Spectrometry (LC/MS)• Matrix Assisted Laser Desorption Ionization MS (MALDI) Peptide
Chrystallography Core
H. Moriyama
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VBMSBiomedical Sciences (Animals and Humans)
Epidemiology
Bacteriology
Virology
Cell Biology
Parasitology
ToxicologyBarletta, Raul Duhamel, Gerald E., Jones, Clinton J.Lou, Marjorie F.Moxley, Rodney A.Osorio, Fernando A.Pattnaik, Asit K., Somerville, Greg,
Herpesvirus
PRRSV
Bacterial Path
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Etsuko MoriyamaSteve Ladunga
Computer Science Mike Fromm
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Pesticide Absorption into the BodyFuzzy Modeling of Skin Permeability CoefficientsTransdermal Delivery of Antisense Oligonucleotides Biosignals & SystemsMedical ImagingBiomedical imagingNoninvasive blood flow velocity measurementSingle molecule imaging and trackingDNA sequencing instrumentation
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The Future at UNL?
Areas of Collaboration?Cross-field: Nanotechnology and molecular biology, Computer modelling; complex systemsMicrobiology of pathogens, drug and vaccine development (Strong Chemistry and Animal Sciences).
Multidisciplinary Cross-department, Cross-campusCollaborations. More Growth in Funding (despite recent NIH budget dips).Unique Niches.