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miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano, Gerard Nuovo, Sung-Suk Suh, Apollinaire Ngankeu, Cristian Taccioli, Flavia Pichiorri, Hansjuerg Alder, Paola Secchiero, Pierluigi Gasparini, Arianna Gonelli, Stefan Costinean, Mario Acunzo, Gerolama Condorelli, Carlo Maria Croce Cancer Cell Volume 16, Issue 6, Pages 498-509 (December 2009) DOI: 10.1016/j.ccr.2009.10.014 Copyright © 2009 Elsevier Inc. Terms and Conditions

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Page 1: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation 

Michela Garofalo, Gianpiero Di Leva, Giulia Romano, Gerard Nuovo, Sung-Suk Suh, Apollinaire Ngankeu, Cristian Taccioli, Flavia Pichiorri, Hansjuerg Alder, Paola Secchiero, Pierluigi Gasparini, Arianna Gonelli, Stefan Costinean, Mario Acunzo, Gerolama Condorelli,

Carlo Maria Croce 

Cancer Cell Volume 16, Issue 6, Pages 498-509 (December 2009)

DOI: 10.1016/j.ccr.2009.10.014

Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 2: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

Figure 1

Cancer Cell 2009 16, 498-509DOI: (10.1016/j.ccr.2009.10.014) Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 3: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

Figure 2

Cancer Cell 2009 16, 498-509DOI: (10.1016/j.ccr.2009.10.014) Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 4: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

Figure 3

Cancer Cell 2009 16, 498-509DOI: (10.1016/j.ccr.2009.10.014) Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 5: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

Figure 4

Cancer Cell 2009 16, 498-509DOI: (10.1016/j.ccr.2009.10.014) Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 6: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

Figure 5

Cancer Cell 2009 16, 498-509DOI: (10.1016/j.ccr.2009.10.014) Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 7: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

Figure 6

Cancer Cell 2009 16, 498-509DOI: (10.1016/j.ccr.2009.10.014) Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 8: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

Figure 7

Cancer Cell 2009 16, 498-509DOI: (10.1016/j.ccr.2009.10.014) Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 9: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation Michela Garofalo, Gianpiero Di Leva, Giulia Romano,

Figure 8

Cancer Cell 2009 16, 498-509DOI: (10.1016/j.ccr.2009.10.014) Copyright © 2009 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

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