MINERALS IODINE

Dr. Vijay Marakala, MBBS, MD.

Assistant professor BIOCHEMISTRY SIMS & RC

IODINE

SOURCE RDA METABOLISM

FUNCTION DEFICIENCY

IODINE - SOURCES

Sea foods

Egg

Dairy products

Iodized salt

Drinking water

Vegetables

IODINE - RDA

150 µg/da

y

IODINE - METABOLISMAbsorptio

n

Upper small

intestine

Transport

Binding loosely

to plasma protein

s

Storage

80% in thyroid gland

Excretion

2/3rd in urine

IODINE - FUNCTION

Required for the synthesis of thyroid

hormonesT4 and T3

IODINE DEFICIENCY - CAUSES

DIETARY DEFECIENCY• Goitre belt

GOITROGENS• Thiocyanates • Thiourea

IODINE DEFICIENCY - FEATURES

Goiter

IODINE DEFICIENCY

Potassium iodideTreatmen

t

MAGNESIUM

MAGNESIUM

Sources RDA Distribution

Functions Disorders

MAGNESIUM - SOURCES

Green leafy

vegetables

Cereals

Nuts

Sea foods

MAGNESIUM - RDA

300-400

mg/day

MAGNESIUM - DISTRIBUTION

Total body magnesium is 25gm

67% in

bone

32% in

cells

Extra cellular magnesium is 1%Plasma magnesium

1.8 – 2.5mg/dl

MAGNESIUM - FUNCTIONSActivator of

many enzymesMaintain normal

muscle and nerve functionNeeded for

healthy bones and teeth

MAGNESIUM - DISORDERS

Hypomagnesaemia

Hypermagnesaemia

HYPOMAGNESAEMIA

CAUSES

Malnutrition, alcoholism

Malabsorption

Renal tubular acidosis

Toxemia of pregnancy

Drugs - diuretics

HYPOMAGNESAEMIA-FEATURESMuscle

cramps and tetanyCardiac

arrhythmias

Ataxia, tremor

HYPERMAGNESAEMIACAUSES Chronic renal failure

Rhabdomyolysis FEATURES Muscle weakness

Hypotension